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Search Results for " alp "

266

抑制剂 & 化合物

143

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T29906	Alprenolol-nbd Alp-NBD
	Alprenolol-nbd is a fluorescent beta-adrenoceptor probe that binds irreversibly to beta-adrenoceptors and non-receptor binding sites.
T83137	ALP/Carbonic anhydrase-IN-1	Carbonic Anhydrase	Metabolism
	ALP/Carbonic anhydrase-IN-1（Compound 1e）为碳酸酐酶（CA）与碱性磷酸酶（ALP）的双效抑制剂。对CA-II、CA-IX、CA-XII和ALP具有显著抑制活性，其IC50值分别为0.44 µM、1.61 µM、0.51 µM和0.107 µM。
T19758	D-alpha-Methylbenzyl isothiocyanate	Others	Others
	D-alpha-Methylbenzyl isothiocyanate 是一种抗氧化剂和手性试剂，可诱导 II 期酶活性。
TP2056L	Acetyl-Calpastatin (184-210)(human) acetate Acetyl-Calpastatin (184-210) (human) acetate(123714-50-1 Free base )	Cysteine Protease	Proteases/Proteasome
	Acetyl-Calpastatin (184-210)(human) acetate 是一种有效，选择性和可逆的钙蛋白酶 (calpain) 抑制剂，对 μ-钙蛋白酶和组织蛋白酶 L 的 Ki 值分别为 0.2 nM 和 6 μM。
T21511L	alpha-Endorphin acetate α-内啡肽,alpha-Endorphin acetate (59004-96-5 Free base)	Others	Others
	alpha-Endorphin acetate 是具有特征生物活性的原阿片黑皮质素家族的相关肽，从单个人类垂体中纯化至同质。
T20889	AalphaC 2-Amino-alpha-carboline,Aalpha C,2-氨基-9H-吡啶[2,3-b]吲哚,Aalpha-C	Others	Others
	AalphaC (2-Amino-alpha-carboline) 是一种潜在的致癌物质。
T1602	Valproic acid sodium salt 丙戊酸钠,Sodium Valproate	Mitophagy; Gamma-secretase; HIV Protease; GABA Receptor; HDAC; Autophagy	Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Proteases/Proteasome; Stem Cells
	Valproic acid sodium salt (Sodium Valproate) 是一种HDAC 抑制剂，可抑制HDAC1的活性，诱导HDAC2的降解。它激活Notch1信号并抑制小细胞肺癌细胞的增殖。它可研究癫痫、偏头痛和双相情感障碍等。
T11630	IFN alpha-IFNAR-IN-1 hydrochloride	Others; IFNAR	Immunology/Inflammation; Others
	IFN alpha-IFNAR-IN-1 hydrochloride 是 IFN-α 和 IFNAR 相互作用的抑制剂。 IFN alpha-IFNAR-IN-1 hydrochloride 抑制 BM-pDCs 的 MVA 诱导的 IFN-α 反应，IC50 为 2-8 μM。
T10290L	Alpertine HCl Win 31665 HCl,Alpertine HCl（27076-46-6 Free base）	Others	Others
	Alpertine HCl 是一种小分子化合物，具有抗神经病作用。
T0355	Valpromide Depamide,Valpramide,丙戊酰胺,Dipropylacetamide,2-propylpentanamide	Epoxide Hydrolase; HSV	Metabolism; Microbiology/Virology
	Valpromide (Dipropylacetamide) 是丙戊酸的羧酰胺衍生物，用于治疗癫痫和一些情感障碍。
T9259	Alpha-calcium ketoglutarate monohydrate	Others	Others
	Alpha-calcium ketoglutarate monohydrate 是 α-酮戊二酸的钙盐形式，参与生物体内的三羧酸循环。
T6432	Calpeptin	Apoptosis; Cysteine Protease; Proteasome	Apoptosis; Proteases/Proteasome; Ubiquitination
	Calpeptin 是一种具有细胞穿透性的calpain 抑制剂，也是cathepsin K 抑制剂，其对人血小板 Calpain I 的ID50值为40 nM。
T9636	Dalpiciclib SHR-6390	CDK	Cell Cycle/Checkpoint
	Dalpiciclib (SHR-6390) 是一种高选择性、口服生物利用度和相当效力的 CDK4 和 CKD6 抑制剂，IC50 分别为 12.4 nM 和 9.9 nM。它通过抑制磷酸化 Rb 蛋白和诱导 G1 细胞周期阻滞在食管鳞状细胞癌中发挥有效的抗肿瘤活性。
T21253	5-alpha-Hydroxy-Laxogenin	Others	Others
	5-alpha-Hydroxy-Laxogenin 是一种应激激素皮质醇抑制剂。
T18916	ALPS N-Ethyl-N-sulfopropylaniline sodium salt	Others	Others
	ALPS (N-Ethyl-N-sulfopropylaniline sodium salt) 是一种生化显色剂。
T76698	Rovalpituzumab	Gamma-secretase	Neuroscience; Proteases/Proteasome; Stem Cells
	Rovalpituzumab 是一种靶向 delta 样蛋白 3 (DLL3) 的人源化单克隆抗体。Rovalpituzumab 可用于合成抗体-活性分子偶联物 (ADC)。Rovalpituzumab 具有抗癌活性，可用于治疗小细胞肺癌 (SCLC)。
TP1909L1	CALP2 acetate(261969-04-4 free base)	CaMK; PDE	Metabolism; Neuroscience
	CALP2 acetate 是一种钙调蛋白拮抗剂，对与 CaM EF-hand/Ca2+-结合位点具有高亲和力，Kd 为 7.9 µM。它有效抑制粘附和脱粒。它也是肺泡巨噬细胞的强激活剂。它抑制 CaM 依赖性磷酸二酯酶活性并增加细胞内 Ca2+ 浓度。
T124500	Alpha-Amyrone Urs-12-en-3-one,Alfa-Amyrenone	Others	Others
	Alpha-Amyrone (Alfa-Amyrenone) 是一种存在于植物 Inula candida (L.) Cass. subsp.地上部分的化合物，Alpha-Amyrone 是一种抗肿瘤化合物。
T6474	Divalproex Sodium Valproate semisodium,Epival,双丙戊酸钠	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Divalproex Sodium (Valproate semisodium) 结合并抑制 γ-氨基丁酸 (GABA) 转氨酶，其抗惊厥活性可通过增加 GABA 脑浓度和抑制分解 GABA 或阻止 GABA 再摄取到神经胶质和神经末梢的酶来发挥。它也是一种 HDAC 抑制剂。由丙戊酸钠和丙戊酸组成，具有抗惊厥和抗癫痫活性。 Divalproex 还可以通过抑制电压敏感的钠通道来抑制重复的神经元放电。
TP1910L1	CALP1 acetate CALP1 acetate(145224-99-3 free base)	CaMK	Neuroscience
	CALP1 acetate 是一种钙调蛋白 (CaM) 激动剂（Kd 为 88 µM），可与 CaM EF-hand/Ca2+ 结合位点结合。 CALP1 通过抑制钙通道的开放来阻断钙流入和细胞凋亡（IC50 为 44.78 µM）。 CALP1 阻断谷氨酸受体通道并阻断储存操作的非选择性阳离子通道。 CALP1 激活依赖于 CaM 的磷酸二酯酶活性。
T22774L	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)	Others	Others
	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) 是延伸因子 1 亚基。真核翻译延伸因子 1 alpha 1 (EEF1A1) 编码延伸因子 alpha 亚基的同种型- 1 复合物，负责将氨酰 tRNA 酶促递送至核糖体。这种亚型（α 1）在脑、胎盘、肺、肝、肾和胰腺中表达，另一种亚型（α 2）在脑、心脏和骨骼肌中表达。这种亚型在 66% 的 Felty 综合征患者中被鉴定为自身抗原。已发现该基因在许多染色体上具有多个拷贝，其中一些（如果不是全部）代表不同的假基因。
T26600	Alpidem Ananxyl,阿尔吡登	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Alpidem (Ananxyl) 可以选择性结合含有α1β2γ2 亚单位的GABAA 受体，具有抗焦虑作用。
T3223	16beta-Methyl-16alpha,17alpha-epoxypregnenolone	Others	Others
	16beta-Methyl-16alpha,17alpha-epoxypregnenolone 用作药物中间体。
T1921	Alpelisib BYL-719	PI3K	PI3K/Akt/mTOR signaling
	Alpelisib (BYL-719) 是一种 PI3Kα 抑制剂 (IC50=5 nM)，具有选择性、有效性和口服活性。Alpelisib 以较低活性抑制 PI3Kβ/γ/δ (IC50=250/290/1200 nM)。Alpelisib 具有抗肿瘤活性，对 PIK3CA 突变肿瘤具有靶向性。
T20489	Benzalphthalide NSC2824,NSC-2824,亚苄基酞,NSC 2824	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Benzalphthalide (NSC-2824) 是一种具有抗 HIV 活性的化合物。
T126521	alpha-Hexylcinnamaldehyde
	alpha-Hexylcinnamaldehyde 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126521，CAS号为 101-86-0。
T22236	Alprenolol hydrochloride 阿普洛尔盐酸盐,盐酸阿普洛尔	5-HT Receptor	GPCR/G Protein; Neuroscience
	Alprenolol hydrochloride 是一种非选择性β受体阻滞剂，也是5-HT1A 受体拮抗剂。
TP1911L	CALP3 acetate(261969-05-5 free base)	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	CALP3 acetate(261969-05-5 free base) 是一种有效的 Ca2+ 通道阻滞剂，可激活 Ca2+ 结合蛋白的 EF 手基序。它可以通过调节钙调蛋白 (CaM)、Ca2+ 通道和泵的活性在功能上模拟增加的 [Ca2+]i。
T19825	X-alpha-Gal	Others	Others
	X-alpha-Gal 是 α-半乳糖苷酶的底物。它用于区分酵母的α-半乳糖苷酶阳性菌株。
T16169	N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride	Others; Proteasome; COX	Immunology/Inflammation; Neuroscience; Others; Proteases/Proteasome; Ubiquitination
	N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride (N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride) 是胰蛋白酶样蛋白酶的抑制剂。 N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride 对 IFN-γ 活性具有抑制作用。
T17326	2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide 2-3-4-6-tetra-o-acetyl-alpha-galactosylpyranosyl-bromide	Others; PROTAC Linker	Others; PROTAC
	2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide (2-3-4-6-tetra-o-acetyl-alpha-galactosylpyranosyl-bromide) 是一种属于 alkyl chain 类的 PROTAC linker，可用于 PROTAC 分子的合成。
T7859	3-Isopropenyl-alpha,alpha-dimethylbenzyl	Others	Others
	3-Isopropenyl-alpha,alpha-dimethylbenzyl 一种生物活性化学品。
T23709	alphaSYN-IN-NAB2 alphaSYN inhibitor NAB2,alphaSYNINNAB2,alphaSYN-IN-NAB2,NAB2,alphaSYN inhibitor-NAB2
	alphaSYN-IN-NAB2 是一种神经元保护剂，是一种由 NAB2基因编码的蛋白质。NAB2 高效且具有选择性地保护多种细胞免受 α-syn 毒性。NAB2 对依赖于 E3 泛素连接酶 Rsp5/Nedd4 的内体转运具有促进作用。NAB2 确定 α-syn 生物学中的一个可活性分子节点，该节点可以纠正其潜在病理学的多个方面，包括功能失调的内体和内质网到高尔基体囊泡的运输。NAB2参与细胞分化、凋亡和应激反应等细胞过程，可用来研究癌症、神经发育和神经元活动。
TNU1627	1-(3’-O-[4,4’-dimethoxytrityl]-alpha-L-threofuranosyl)uridine
	1-(3’-O-[4,4’-dimethoxytrityl]-alpha-L-threofuranosyl)uridine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TNU1627，CAS号为 325683-90-7。
T25056	Alphostatin
	Alphostatin is an alkaline phosphatase inhibitor isolated from Bacillus megaterium.
T63218	Encephalitic alphavirus-IN-1
	Encephalitic alphavirus-IN-1 能够抑制委内瑞拉马脑炎病毒 (VEEV) (EC50: 0.24 μM)和东部马脑炎病毒 (EEEV) (EC50: 0.16 μM)的活性。Encephalitic alphavirus-IN-1 没有明显的细胞毒性，而且表现出较强的小鼠血浆稳定性。
TNU0639	2’,3’-O-Isopropylidene-4’-alpha-azido-uridine
	Nucleoside-Azido-nucleoside
T33529	m-Toluidine, alpha-(methylsulfonyl)-4-(nonyloxy)-
	m-Toluidine, alpha-(methylsulfonyl)-4-(nonyloxy)- is a bioactive chemical.
TNU1228	1,2,3,5-Tetra-O-benzoyl-4-alpha-C-vinyl-D-ribofuranose
	Carbohydrate Derivatives
T123978	trans-3-Oxo-alpha-ionol
	trans-3-Oxo-alpha-ionol 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T123978。
T126303	10alpha-Hydroxyepigambogic acid
	10alpha-Hydroxyepigambogic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126303。
TNU1336	1-(alpha-L-Threofuranosyl)thymine
	Nucleoside Derivatives - L-Nucleosides
T123925	Antibiotic LL-D253alpha
	Antibiotic LL-D253alpha 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T123925，CAS号为 92589-99-6。
T75418	alpha-1,3-Galactosyltransferase (GTB)
	Alpha-1,3-Galactosyltransferase (GTB) 催化异种抗原或 α-半乳糖 (α-Gal) 表位的合成，通过将 UDP-Gal 中的半乳糖转移到类型1或类型2的 αFuc1→2βGal-R (H)-终止受体上。
T80181	MitTx-alpha	Sodium Channel	Membrane transporter/Ion channel
	MitTx-alpha为MitTx的亚基，该化合物为一高效、持久、选择性酸敏感离子通道(ASIC)激动剂。该化合物在中性pH条件下优先选择ASIC1亚型，而在更酸性条件(pH<6.5)时，可显著增强(>100倍)质子诱导的ASIC2a通道活性。
T75794	Acetyl-Calpastatin(184-210)(human) TFA
	Acetyl-Calpastatin(184-210)(human) TFA 是一种有效，选择性和可逆的钙蛋白酶 (calpain) 抑制剂，对 μ-钙蛋白酶和组织蛋白酶 L 的Ki 值分别为 0.2 nM 和 6 μM。
TP1533	HIF-1 alpha (556-574) HIF-1 alpha 556-574
	HIF-1 alpha (556-574) is a hypoxia-inducible factor-1 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1subunit is stabilized in response to a lack of oxygen. Thi
TP2217	alpha-1 antitrypsin fragment	Others	Others
	Alpha-1 antitrypsin (A1AT) is known as a serum trypsin inhibitor and is a protease inhibitor belonging to the serpin superfamily. Alpha-1 antitrypsin is a single-chain glycoprotein consisting of 394 amino acids in the mature form and exhibits a number of
TP2056	Acetyl-Calpastatin(184-210)(human) Acetyl-Calpastatin (184-210) (human)
	Selective calpain inhibitor. Strongly inhibits calpain I (Ki = 0.2 nM) and II but does not inhibit papain, trypsin and cathepsin L (Ki = 6 μM). Increases secretion of amyoid β-protein (Aβ) 42, Aβ40 and Aβ42 ratio.
T75790	CALP2 TFA
	CALP2 TFA 是一种钙调蛋白 (CaM) 拮抗剂 (Kd 为 7.9 µM)，以亲和力结合CaMEF-hand/Ca2+结合位点。CALP2 TFA 抑制CaM 依赖性磷酸二酯酶 (phosphodiesterase) 活性并增加细胞内 Ca2+浓度。CALP2 TFA 有效抑制粘附和脱粒。CALP2 TFA 还是肺泡巨噬细胞的强激活剂。

化合物

Alprenolol-nbd

Cat.No: T29906

Synonym: Alp-NBD

ALP/Carbonic anhydrase-IN-1

Cat.No: T83137

Target: Carbonic Anhydrase

D-alpha-Methylbenzyl isothiocyanate

Cat.No: T19758

Target: Others

Acetyl-Calpastatin (184-210)(human) acetate

Cat.No: TP2056L

Synonym: Acetyl-Calpastatin (184-210) (human) acetate(123714-50-1 Free base )

Target: Cysteine Protease

alpha-Endorphin acetate

Cat.No: T21511L

Synonym: α-内啡肽,alpha-Endorphin acetate (59004-96-5 Free base)

Target: Others

Cat.No: T20889

Synonym: 2-Amino-alpha-carboline,Aalpha C,2-氨基-9H-吡啶[2,3-b]吲哚,Aalpha-C

Target: Others

Valproic acid sodium salt

Cat.No: T1602

Synonym: 丙戊酸钠,Sodium Valproate

Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, HDAC, Autophagy

IFN alpha-IFNAR-IN-1 hydrochloride

Cat.No: T11630

Target: Others, IFNAR

Alpertine HCl

Cat.No: T10290L

Synonym: Win 31665 HCl,Alpertine HCl（27076-46-6 Free base）

Target: Others

Cat.No: T0355

Synonym: Depamide,Valpramide,丙戊酰胺,Dipropylacetamide,2-propylpentanamide

Target: Epoxide Hydrolase, HSV

Alpha-calcium ketoglutarate monohydrate

Cat.No: T9259

Target: Others

Cat.No: T6432

Target: Apoptosis, Cysteine Protease, Proteasome

Cat.No: T9636

Synonym: SHR-6390

Target: CDK

5-alpha-Hydroxy-Laxogenin

Cat.No: T21253

Target: Others

Cat.No: T18916

Synonym: N-Ethyl-N-sulfopropylaniline sodium salt

Target: Others

Cat.No: T76698

Target: Gamma-secretase

CALP2 acetate(261969-04-4 free base)

Cat.No: TP1909L1

Target: CaMK, PDE

Alpha-Amyrone

Cat.No: T124500

Synonym: Urs-12-en-3-one,Alfa-Amyrenone

Target: Others

Divalproex Sodium

Cat.No: T6474

Synonym: Valproate semisodium,Epival,双丙戊酸钠

Target: HDAC

Cat.No: TP1910L1

Synonym: CALP1 acetate(145224-99-3 free base)

Target: CaMK

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)

Cat.No: T22774L

Target: Others

Cat.No: T26600

Synonym: Ananxyl,阿尔吡登

Target: GABA Receptor

16beta-Methyl-16alpha,17alpha-epoxypregnenolone

Cat.No: T3223

Target: Others

Cat.No: T1921

Synonym: BYL-719

Target: PI3K

Benzalphthalide

Cat.No: T20489

Synonym: NSC2824,NSC-2824,亚苄基酞,NSC 2824

Target: HIV Protease

alpha-Hexylcinnamaldehyde

Cat.No: T126521

Alprenolol hydrochloride

Cat.No: T22236

Synonym: 阿普洛尔盐酸盐,盐酸阿普洛尔

Target: 5-HT Receptor

CALP3 acetate(261969-05-5 free base)

Cat.No: TP1911L

Target: Calcium Channel

Cat.No: T19825

Target: Others

N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride

Cat.No: T16169

Synonym: N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride

Target: Others, Proteasome, COX

2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide

Cat.No: T17326

Synonym: 2-3-4-6-tetra-o-acetyl-alpha-galactosylpyranosyl-bromide

Target: Others, PROTAC Linker

3-Isopropenyl-alpha,alpha-dimethylbenzyl

Cat.No: T7859

Target: Others

alphaSYN-IN-NAB2

Cat.No: T23709

Synonym: alphaSYN inhibitor NAB2,alphaSYNINNAB2,alphaSYN-IN-NAB2,NAB2,alphaSYN inhibitor-NAB2

1-(3’-O-[4,4’-dimethoxytrityl]-alpha-L-threofuranosyl)uridine

Cat.No: TNU1627

Cat.No: T25056

Encephalitic alphavirus-IN-1

Cat.No: T63218

2’,3’-O-Isopropylidene-4’-alpha-azido-uridine

Cat.No: TNU0639

m-Toluidine, alpha-(methylsulfonyl)-4-(nonyloxy)-

Cat.No: T33529

1,2,3,5-Tetra-O-benzoyl-4-alpha-C-vinyl-D-ribofuranose

Cat.No: TNU1228

trans-3-Oxo-alpha-ionol

Cat.No: T123978

10alpha-Hydroxyepigambogic acid

Cat.No: T126303

1-(alpha-L-Threofuranosyl)thymine

Cat.No: TNU1336

Antibiotic LL-D253alpha

Cat.No: T123925

alpha-1,3-Galactosyltransferase (GTB)

Cat.No: T75418

Cat.No: T80181

Target: Sodium Channel

Acetyl-Calpastatin(184-210)(human) TFA

Cat.No: T75794

HIF-1 alpha (556-574)

Cat.No: TP1533

Synonym: HIF-1 alpha 556-574

alpha-1 antitrypsin fragment

Cat.No: TP2217

Target: Others

Acetyl-Calpastatin(184-210)(human)

Cat.No: TP2056

Synonym: Acetyl-Calpastatin (184-210) (human)

Cat.No: T75790

Cat. No.	Product Name	Target	Signaling Pathways
T4852	Trimyristin Trimyristoylglycerol,Tritetradecanoin,三肉豆蔻酸甘油酯,Glyceryl trimyristate,甘油三肉豆蔻酸酯,1,2,3-Tritetradecanoylglycerol	Phosphatase; Endogenous Metabolite; AChE	Metabolism; Neuroscience
	Trimyristin (Tritetradecanoin) 是一种 Myristica fragransHoutt 的有效成分，能够显著抑制乙酰胆碱酯酶 (AChE)，酸性和碱性磷酸酶 (ACP/ALP) 特性。它对 AChE，ACP 和 ALP 的 IC50分别为 0.11、0.16 和 0.18 mM。
TN6785	Dihydrocatalpol (2S,3R,4S,5S,6R)-2-[[(1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-2,4,5,5a,6,6a-hexahydro-1bH-oxireno[5,6]cyclopenta[1,3-c]pyran-2-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol	Others	Others
	Dihydrocatalpol ((2S,3R,4S,5S,6R)-2-[[(1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-2,4,5,5a,6,6a-hexahydro-1bH-oxireno[5,6]cyclopenta[1,3-c]pyran-2-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol) 是一种从地黄中提取的天然产物。
T2O2744	alpha-Naphthoflavone 苯并黄素；α-萘黄酮；7,8-苯并黄酮,7,8-benzoflavone,α-萘黄酮	Aromatase	Endocrinology/Hormones
	alpha-Naphthoflavone (7,8-benzoflavone) 是合成的黄酮类化合物，是一种竞争性芳香酶抑制剂，其IC50=0.5 μM，Ki=0.2 μM。
T3248	alpha-Boswellic acid α-Boswellic acid,α-乳香酸	Others	Others
	alpha-Boswellic acid (α-Boswellic acid) 是一种从乳香中提取得到的五环三萜类天然产物，具有抗惊厥和抗癌作用。在动物体内，它是预防和减少阿尔茨海默病标志物，可用于阿尔茨海默病的研究。
TN2216	Alpha-Solamarine Solamarine,奥洲边茄碱,澳洲茄边碱
	Alpha-Solamarine (Solamarine) 是从 Solanum nigrum 中分离得到的一种糖苷生物碱。Alpha-Solamarine 对 Globodera pallid 具有抑制作用，可能用于植物防御。
TN7228	11-oxo-alpha-amyrin Neoilexonol
	11-oxo-alpha-amyrin (Neoilexonol) 是一种从Leonurus japonicus (Lamiaceae) 提取出的三萜化合物，是一种天然化合物。
TN3609	Catalposide Hydroxybenzoyl catalpol	ERK; IL Receptor; TNF; NOS; NF-κB; NO Synthase; PPAR; Autophagy	Apoptosis; Autophagy; DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Metabolism; NF-κB
	Catalposide 是一种有效的 (HO)-1 诱导剂，从 Catalpa ovate G. Don（紫葳科）中分离出来。 Catalposide 具有抗氧化、抗细胞凋亡、抗微生物、抗肿瘤和抗炎特性。
T4884	alpha-D-glucose α-D-Glucose,α-葡萄糖,alpha-Glucose,α-Dextrose	Others; Endogenous Metabolite	Metabolism; Others
	alpha-D-glucose (α-Dextrose) 是内源性代谢产物的一种。
TN3396	Alpinumisoflavone acetate 4'-O-Acetylalpinumisoflavone	Others	Others
	Alpinumisoflavone acetate (4'-O-Acetylalpinumisoflavone) 是一种新的alpinumisoflavone 衍生物。Alpinumisoflavone 在0.63 ug/disc 时强烈抑制生殖管生长。
T7050	alpha-Tocopherolquinone 托可醌,Metarene	Antioxidant	oxidation-reduction
	alpha-Tocopherolquinone (Metarene) 会下调线粒体的呼吸活动。在还原为生育酚氢醌后，它还显示出抗氧化活性。在大鼠缺氧期间，已发现它的水平升高。
T1717	alpha-Mangostin α-倒捻子素,α-Mangostin,Mangostin	Apoptosis; Virus Protease; Dehydrogenase; Reactive Oxygen Species; Antibacterial; Antifungal	Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	alpha-Mangostin (Mangostin) 是有多种生物活性的膳食呫吨酮。它是一种IDH1突变体的抑制剂，Ki 值为 2.85 μM。
TMA2394	DL-alpha-Tocopherol DL-α-生育酚,消旋-α-生育酚,DL-α-Tocopherol,Alpha-Tochopherol,Ephanyl	Antioxidant; Ferroptosis	Apoptosis; oxidation-reduction
	DL-alpha-Tocopherol (Ephanyl) 是一种合成维生素 E，能保护皮肤成纤维细胞免受紫外线的细胞毒性作用，具有抗氧化作用。
T3378	Alpha-Estradiol α-雌二醇,Alfatradiol,雌二醇,17α-Estradiol,Epiestrol,Epiestradiol	Estrogen/progestogen Receptor; Reductase; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Alpha-Estradiol (Epiestradiol) 是一种雌性激素，可抑制5α-reductase，在雄原性脱发的研究中有潜力。
T4768	Diethyl oxalpropionate 草酰丙酸二乙酯,HYL 2-METHYL-3-OXOSUCCINATE	Others; Endogenous Metabolite	Metabolism; Others
	Diethyl oxalpropionate (HYL 2-METHYL-3-OXOSUCCINATE) 是一种合成 PDMMLA 的中间体。其中 PDMMLA 的衍生物可用于纳米粒子的合成和研究。
TN3847	Dihydroalpinumisoflavone
	Dihydroalpinumisoflavone 是一种从 Crotalaria madurensis 的叶子和茎中提取的天然产品。
TN7047	6-O-Methylcatalpol	Others	Others
	6-O-Methylcatalpol 是从 S. ningpoensis 的根中分离得到的天然产物。
T3867	Alpinetin 山姜素,(-)-alpinetin	BCL; PPAR	Apoptosis; DNA Damage/DNA Repair; Metabolism
	Alpinetin ((-)-alpinetin) 是从草豆蔻中分离得到的一种黄酮类天然产物，能够活化PPAR-γ，具有抗炎、抗菌活性。它通过抑制增殖、调节 Bcl-2 家族和 XIAP 表达、释放细胞色素 c 和激活 caspase 具有很强的抗肝癌和胰腺癌细胞作用。
T2780	Catalpol 梓醇,Catalpinoside,Digitalis purpurea L	Others; HBV	Microbiology/Virology; Others
	Catalpol (Catalpinoside) 是一种在Rehmannia glutinosa 中发现的鸢尾花苷，具有神经保护、降血糖、抗癌、抗痉挛、抗氧化、抗HBV 和抗肝炎病毒作用。
T3368	Alpha-Hederin α常春藤皂甙,Helixin,Tauroside E,α-Hederin,Hederoside C	Apoptosis; Others	Apoptosis; Others
	Alpha-Hederin (Tauroside E) 是存在于黑种草种子中的一种单桥糖三萜皂苷，具有抗肿瘤作用。它可通过激活线粒体依赖性途径抑制胃癌细胞增殖，诱导凋亡，并有活性氧生成和谷胱甘肽减少。
TN1372	Alpha-Amyrin alpha-Amyrenol,α-Amyrin,alpha-Amyrine,Viminalol,α-香树脂醇	P450; Serine Protease; ROS	Immunology/Inflammation; Metabolism; Proteases/Proteasome
	Alpha-Amyrin (alpha-Amyrine) 是一种具有抗肿瘤作用的胰蛋白酶和糜蛋白酶抑制剂。 alpha-Amyrin 可用于作为肝调节剂的研究。
T5S1981	alpha-Cyperone (+)-α-Cyperone,α-香附酮,α-Cyperone	Others; Endogenous Metabolite	Metabolism; Others
	alpha-Cyperone (α-Cyperone) 与 IL-6, Cox-2, Cdc42, Nck-2, Rac1 的表达下调相关,从而能够抑制炎症反应。
T3698	alpha-Asarone α-Asarone,trans-Asarone,α-细辛脑	P450; GABA Receptor; HMG-CoA Reductase	Membrane transporter/Ion channel; Metabolism; Neuroscience
	alpha-Asarone (trans-Asarone) 是来自胡萝卜的一种天然产物，具有抗抑郁等功效。
T7064	Valproic Acid Sodium valproate,2-Propylpentanoic Acid,丙戊酸,VPA,Depakine,2-Propylvaleric Acid	Mitophagy; Gamma-secretase; HIV Protease; GABA Receptor; Sodium Channel; HDAC; Autophagy	Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Proteases/Proteasome; Stem Cells
	Valproic Acid (2-Propylpentanoic Acid) 是一种 HDAC 抑制剂，可抑制 HDAC1 活性，诱导 HDAC2 降解，具有口服活性。Valproic Acid 可以用于癫痫和躁郁症的研究。
TN3397	Alpinumisoflavone	ERK; LDL; NF-κB; MEK; MAPK; Antifection	MAPK; Metabolism; Microbiology/Virology; NF-κB
	Alpinumisoflavone has atheroprotective effects, may result from their ability to upregulate mechanisms promoting HDL-cholesterol and bile acid formation, it is endowed with estrogenic properties accounting, at least in part, for E. lysistemon effects. Alp
TN3332	9alpha,11-Dihydroxydrim-7-en-6-one	Others	Others
	9alpha,11-Dihydroxydrim-7-en-6-one 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3332，CAS号为 127681-58-7。
TN1379	Alphitolic acid 麦珠子酸	NF-κB; Akt; p53	Apoptosis; Cytoskeletal Signaling; NF-κB; PI3K/Akt/mTOR signaling
	Alphitolic acid is a potent Hh/GLI signaling inhibitor, it shows an important relationship between Hh/GLI signaling inhibition, the decrease of BCL2, and cytotoxicity against cancer cells.
TN3199	6alpha-Hydroxymaackiain	Others	Others
	6alpha-Hydroxymaackiain is a natural product from Derris robusta.
TN3375	alpha-Conidendrin	Others	Others
	alpha-Conidendrin是一种天然产物，属于松科铁杉属，其产品编号为 TN3375，CAS号为 85699-62-3。alpha-Conidendrin可用作对照参考。
TN4030	Eudesm-4(15)-ene-3alpha,11-diol
	Eudesm-4(15)-ene-3alpha,11-diol 是一种来源于Eudesm-4(15)-ene-3alpha,11-diol 的化合物。
TMA2419	Catalponol	cAMP	GPCR/G Protein
	Catalponol can enhance dopamine biosynthesis by inducing TH activity and protect against L-DOPA-induced cytotoxicity in PC12 cells, which was mediated by the increased levels of cyclic AMP.
TN3390	alpha-Peltatin	Others	Others
	alpha-Peltatin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3390，CAS号为 568-53-6。
TN2604	12alpha-Hydroxyevodol	Others	Others
	12alpha-Hydroxyevodol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2604，CAS号为 120722-04-5。
TN1590	DL-alpha-Tocopherylacetate
	Dl-alpha-tocopheryl acetate is a dietary supplement.
TN4526	Methyl 2alpha-hydroxyhardwickiate	Others	Others
	Methyl 2alpha-hydroxyhardwickiate 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4526，CAS号为 50428-93-8。
TN5602	Neocaesalpin L
	Neocaesalpin L is a natural product from Caesalpinia minax HANCE.
TN2557	1-O-Deacetyl-2alpha-hydroxykhayanolide E	Others	Others
	1-O-Deacetyl-2alpha-hydroxykhayanolide E是一种天然产物，属于楝科桃花心木属，其产品编号为 TN2557，CAS号为 1189801-51-1。1-O-Deacetyl-2alpha-hydroxykhayanolide E可用作对照参考。
TN2655	17alpha-Neriifolin	Others	Others
	17alpha-Neriifolin and 17alpha-Deacetyltanghinin have little anti-proliferative activity, indicating that the 17beta configuration is critical for the anti-proliferative activity of these compounds.
TN2590	11alpha,12alpha-Oxidotaraxerol palmitate	Others	Others
	11alpha,12alpha-Oxidotaraxerol palmitate shows selective cytotoxicity against HCT-8, Bel-7402, BGC-823, A549 and A2780.
TN2988	3alpha-Acetoxy-20(29)-lupene-23,28-dioic acid	Others	Others
	3alpha-Acetoxy-20(29)-lupene-23,28-dioic acid 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2988，CAS号为 83725-41-1。
T83467	10-O-Trans-p-methoxycinnamoylcatalpol
	10-O-Trans-p-methoxycinnamoylcatalpol 表现出抗氧化特性，DPPH 自由基清除实验中显示其 IC50 为 0.37 μM/mL。
TN3294	8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate	NADPH-oxidase; P450; MAO	Immunology/Inflammation; Metabolism; Neuroscience
	8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes.
TN3197	6alpha-Hydroxycleroda-3,13-dien-16,15-olid-18-oic acid	Others	Others
	(-)-6β-Hydroxy-5β,8β,9β,10α-cleroda-3,13-dien-16,15-olid-18-oic acid is one alpha- glucosidase inhibitory constituent from Duranta repens.
TN3932	ent-11alpha-Hydroxyabieta-8(14),13(15)-dien-16,12alpha-olide	Others	Others
	ent-11alpha-Hydroxyabieta-8(14),13(15)-dien-16,12alpha-olide shows significant cytotoxic activity against ANA-1 and Jurkat cells with IC50 values 7.12 x 10(-3) and 1.79 x 10(-2) microM.
TN4719	Otophylloside B 4'''-O-alpha-L-cymaropyranoside	Others	Others
	Otophylloside B 4'''-O-alpha-L-cymaropyranoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4719，CAS号为 171422-82-5。
TN2843	2alpha-Hydroxyeupatolide 8-O-angelate	Others	Others
	2alpha-Hydroxyeupatolide 8-O-angelate is a natural product from Eupatorium chinense var. tozanense.
TN3954	ent-7alpha,9-Dihydroxy-15-oxokaur-16-en-19,6bet-olide	Others	Others
	ent-7alpha,9-Dihydroxy-15-oxokaur-16-en-19,6bet-olide 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3954，CAS号为 59885-89-1。
TN2664	19alpha-Hydroxyfern-7-ene	Others	Others
	19alpha-Hydroxyfern-7-ene 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2664，CAS号为 70588-12-4。
TN3384	alpha-Epoxydihydroartemisinic acid	Others	Others
	alpha-Epoxydihydroartemisinic acid 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3384，CAS号为 380487-65-0。
TN2402	Catalponol methylthiomethyl ether	Others	Others
	Catalponol methylthiomethyl ether is a natural product from plants
TN3565	Caesalpine A	Others	Others
	Caesalpine A is a natural product from Caesalpinia minax.
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天然产物

Cat.No: T4852

Synonym: Trimyristoylglycerol,Tritetradecanoin,三肉豆蔻酸甘油酯,Glyceryl trimyristate,甘油三肉豆蔻酸酯,1,2,3-Tritetradecanoylglycerol

Target: Phosphatase, Endogenous Metabolite, AChE

Dihydrocatalpol

Cat.No: TN6785

Synonym: (2S,3R,4S,5S,6R)-2-[[(1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-2,4,5,5a,6,6a-hexahydro-1bH-oxireno[5,6]cyclopenta[1,3-c]pyran-2-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

Target: Others

alpha-Naphthoflavone

Cat.No: T2O2744

Synonym: 苯并黄素；α-萘黄酮；7,8-苯并黄酮,7,8-benzoflavone,α-萘黄酮

Target: Aromatase

alpha-Boswellic acid

Cat.No: T3248

Synonym: α-Boswellic acid,α-乳香酸

Target: Others

Alpha-Solamarine

Cat.No: TN2216

Synonym: Solamarine,奥洲边茄碱,澳洲茄边碱

11-oxo-alpha-amyrin

Cat.No: TN7228

Synonym: Neoilexonol

Cat.No: TN3609

Synonym: Hydroxybenzoyl catalpol

Target: ERK, IL Receptor, TNF, NOS, NF-κB, NO Synthase, PPAR, Autophagy

alpha-D-glucose

Cat.No: T4884

Synonym: α-D-Glucose,α-葡萄糖,alpha-Glucose,α-Dextrose

Target: Others, Endogenous Metabolite

Alpinumisoflavone acetate

Cat.No: TN3396

Synonym: 4'-O-Acetylalpinumisoflavone

Target: Others

alpha-Tocopherolquinone

Cat.No: T7050

Synonym: 托可醌,Metarene

Target: Antioxidant

alpha-Mangostin

Cat.No: T1717

Synonym: α-倒捻子素,α-Mangostin,Mangostin

Target: Apoptosis, Virus Protease, Dehydrogenase, Reactive Oxygen Species, Antibacterial, Antifungal

DL-alpha-Tocopherol

Cat.No: TMA2394

Synonym: DL-α-生育酚,消旋-α-生育酚,DL-α-Tocopherol,Alpha-Tochopherol,Ephanyl

Target: Antioxidant, Ferroptosis

Alpha-Estradiol

Cat.No: T3378

Synonym: α-雌二醇,Alfatradiol,雌二醇,17α-Estradiol,Epiestrol,Epiestradiol

Target: Estrogen/progestogen Receptor, Reductase, Endogenous Metabolite

Diethyl oxalpropionate

Cat.No: T4768

Synonym: 草酰丙酸二乙酯,HYL 2-METHYL-3-OXOSUCCINATE

Target: Others, Endogenous Metabolite

Dihydroalpinumisoflavone

Cat.No: TN3847

6-O-Methylcatalpol

Cat.No: TN7047

Target: Others

Cat.No: T3867

Synonym: 山姜素,(-)-alpinetin

Target: BCL, PPAR

Cat.No: T2780

Synonym: 梓醇,Catalpinoside,Digitalis purpurea L

Target: Others, HBV

Alpha-Hederin

Cat.No: T3368

Synonym: α常春藤皂甙,Helixin,Tauroside E,α-Hederin,Hederoside C

Target: Apoptosis, Others

Cat.No: TN1372

Synonym: alpha-Amyrenol,α-Amyrin,alpha-Amyrine,Viminalol,α-香树脂醇

Target: P450, Serine Protease, ROS

alpha-Cyperone

Cat.No: T5S1981

Synonym: (+)-α-Cyperone,α-香附酮,α-Cyperone

Target: Others, Endogenous Metabolite

alpha-Asarone

Cat.No: T3698

Synonym: α-Asarone,trans-Asarone,α-细辛脑

Target: P450, GABA Receptor, HMG-CoA Reductase

Cat.No: T7064

Synonym: Sodium valproate,2-Propylpentanoic Acid,丙戊酸,VPA,Depakine,2-Propylvaleric Acid

Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, Sodium Channel, HDAC, Autophagy

Alpinumisoflavone

Cat.No: TN3397

Target: ERK, LDL, NF-κB, MEK, MAPK, Antifection

9alpha,11-Dihydroxydrim-7-en-6-one

Cat.No: TN3332

Target: Others

Alphitolic acid

Cat.No: TN1379

Synonym: 麦珠子酸

Target: NF-κB, Akt, p53

6alpha-Hydroxymaackiain

Cat.No: TN3199

Target: Others

alpha-Conidendrin

Cat.No: TN3375

Target: Others

Eudesm-4(15)-ene-3alpha,11-diol

Cat.No: TN4030

Cat.No: TMA2419

Target: cAMP

alpha-Peltatin

Cat.No: TN3390

Target: Others

12alpha-Hydroxyevodol

Cat.No: TN2604

Target: Others

DL-alpha-Tocopherylacetate

Cat.No: TN1590

Methyl 2alpha-hydroxyhardwickiate

Cat.No: TN4526

Target: Others

Cat.No: TN5602

1-O-Deacetyl-2alpha-hydroxykhayanolide E

Cat.No: TN2557

Target: Others

17alpha-Neriifolin

Cat.No: TN2655

Target: Others

11alpha,12alpha-Oxidotaraxerol palmitate

Cat.No: TN2590

Target: Others

3alpha-Acetoxy-20(29)-lupene-23,28-dioic acid

Cat.No: TN2988

Target: Others

10-O-Trans-p-methoxycinnamoylcatalpol

Cat.No: T83467

8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate

Cat.No: TN3294

Target: NADPH-oxidase, P450, MAO

6alpha-Hydroxycleroda-3,13-dien-16,15-olid-18-oic acid

Cat.No: TN3197

Target: Others

ent-11alpha-Hydroxyabieta-8(14),13(15)-dien-16,12alpha-olide

Cat.No: TN3932

Target: Others

Otophylloside B 4'''-O-alpha-L-cymaropyranoside

Cat.No: TN4719

Target: Others

2alpha-Hydroxyeupatolide 8-O-angelate

Cat.No: TN2843

Target: Others

ent-7alpha,9-Dihydroxy-15-oxokaur-16-en-19,6bet-olide

Cat.No: TN3954

Target: Others

19alpha-Hydroxyfern-7-ene

Cat.No: TN2664

Target: Others

alpha-Epoxydihydroartemisinic acid

Cat.No: TN3384

Target: Others

Catalponol methylthiomethyl ether

Cat.No: TN2402

Target: Others

Cat.No: TN3565

Target: Others

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