首页工具

登录

搜索结果

Search Results for " anti-allergic "

47

抑制剂 & 化合物

35

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T5424	Etosalamide 依托柳胺,Ethosalamide	Others	Others
	Etosalamide (Ethosalamide) 是一种解热缓解疼痛的试剂。它具有抗炎作用，可用于研究过敏性疾病。
T21404	Fluticasone furoate Veramyst,Allermist,Avamys,糠酸氟替卡松,Fluticasone furoate	Glucocorticoid Receptor	Endocrinology/Hormones
	Fluticasone furoate (Avamys) 是一种合成的三氟化皮质类固醇，衍生自氟替卡松，Kd 为 0.3 nM。Fluticasone furoate 具有有效的抗炎、抗哮喘活性和低全身暴露。Fluticasone furoate 可用作过敏性鼻炎治疗研究的鼻喷雾剂。
T4348	Syk Inhibitor II	5-HT Receptor; Syk	Angiogenesis; GPCR/G Protein; Neuroscience; Tyrosine Kinase/Adaptors
	Syk Inhibitor II 是一种可渗透细胞、具有 ATP 竞争性的嘧啶-甲酰胺化合物，可选择性且可逆地抑制 Syk，IC50为 41 nM。
T5449	Bamaquimast F 10126,L 0042,巴马司特	Proton pump	Membrane transporter/Ion channel
	Bamaquimast (L 0042) 是一种抗哮喘药。
T12412L	PDK4-IN-1 hydrochloride	Apoptosis; PDK	Apoptosis; PI3K/Akt/mTOR signaling
	PDK4-IN-1 hydrochloride 是一种蒽醌衍生物，对丙酮酸脱氢酶激酶 4有抑制作用，IC50为 84 nM，具有口服活性。它抑制细胞转化和细胞增殖并诱导细胞凋亡。它具有抗过敏，抗糖尿病和抗癌作用。
T0147	Clemastine fumarate HS-592 (fumarate),富马酸氯马斯汀,Meclastine fumarate,Meclastine (fumarate)	Autophagy; Histamine Receptor	Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Clemastine fumarate (Meclastine (fumarate)) 是一种合成乙醇胺，具有抗胆碱能、镇静和组胺 H1 拮抗作用。
T0188	Fluticasone (propionate) 丙酸氟替卡松,CCI-187881,氟替卡松丙酸酯,Fluticasone propionate	Glucocorticoid Receptor; Virus Protease; Estrogen/progestogen Receptor; Phospholipase; Endogenous Metabolite	Endocrinology/Hormones; Metabolism; Microbiology/Virology
	Fluticasone propionate (CCI-187881) 是一种选择性糖皮质激素受体激动剂，是一种局部抗炎激素，亲和力KD 为 0.5 nM。具有抗病毒活性。
T15772	Lodoxamide tromethamine U-42585E	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Lodoxamide tromethamine 是一种的肥大细胞稳定剂，具有抗过敏特性，可用于治疗哮喘和过敏性结膜炎的研究。
T7812	Acitazanolast MTCC,阿扎司特,WP-871	Others	Others
	Acitazanolast (WP-871) 是一种抗过敏候选药物。
T27159	DF-1111301 DF1111301,DF 1111301	Platelet aggregation; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience; Others
	DF-1111301 是一种具有抗组胺 H1和抗PAF活性的新型抗过敏化合物。
T10945	D18024	Others	Others
	D18024 是一种酞嗪酮的衍生物，显示出抗过敏和抗组胺活性。
T1531	Mometasone furoate 糠酸莫美他松,糠酸莫米松,Sch32088	Glucocorticoid Receptor	Endocrinology/Hormones
	Mometasone furoate (Sch32088) 是糖皮质激素受体激动剂，具有抗炎和抗过敏作用。它是皮质固醇类试剂，动物模型中，可局部应用于气道炎症、慢性皮肤湿疹、哮喘。
T21361	Alclometasone dipropionate Vaderm,Sch 22219,Aclovate,Delonal	Others	Others
	Alclometasone dipropionate （Sch 22219）是一种人工合成的糖皮质激素，属于类固醇化合物，具有抗增生、抗炎、抗过敏、止痒和收缩血管的作用，可用于研究皮肤炎症。
T68094	Lodoxamide ethyl	Others	Others
	lodoxamide ethyl 是一种新的口服活性抗过敏化合物，可用于预防抗原诱导的支气管收缩和阻断皮肤过敏反应。
T0298	Dimenhydrinate 茶苯海明,Dramamine,Chloranautine,乘晕宁,Vomex A	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Dimenhydrinate (Vomex A) 是一种乙醇胺和组胺拮抗剂，具有抗过敏活性，可作为抗催吐剂。
T11581	HSR6071	Others	Others
	HSR6071 是一种新型具有口服活性和有效性的抗过敏制剂，能抑制被动皮肤过敏反应 (PCA)。HSR6071 在大鼠实验性哮喘模型中显示出抗哮喘活性。
T50001	Tinoridine ethyl 2-amino-6-benzyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylate,替诺立定	P450	Metabolism
	Tinoridine 通过抑制环氧合酶-2（COX-2）的产生来发挥作用，具有抗炎、抗过敏和抗凝血等活性。
T3979	Emedastine LY188695,依美斯汀,Emadine	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Emedastine (LY188695) 是一种可口服的，选择性和高亲和力的组胺 H1受体拮抗剂，Ki 值为 1.3 nM。它是苯并咪唑衍生物，可用于过敏性鼻炎、过敏性皮肤疾病和过敏性结膜炎的研究。
T0217L	(+)-Dropropizine (+)-Dropropizine,左羟丙哌嗪	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	(+)-Dropropizine 可以抑制组胺受体，抗过敏，并通过调节参与咳嗽反射的神经肽和干扰感觉神经末梢的刺激激活来减少咳嗽。
T0219	Valdecoxib 伐地考昔,代他考昔,SC 65872	COX	Immunology/Inflammation; Neuroscience
	Valdecoxib (SC 65872) 是可口服的高选择性 COX-2抑制剂，对 COX-2 和 COX-1 的 IC50值分别为 5 nM 和 140 μM，可用于治疗骨关节炎、类风湿性关节炎以及痛经和经期症状。
T0977	Medrysone Gimeracil,6α-Methyl-11β-hydroxyprogesterone,6A-甲基-11B-羟孕酮,甲羟松	Glucocorticoid Receptor; Others	Endocrinology/Hormones; Others
	Medrysone (6α-Methyl-11β-hydroxyprogesterone) 是局部合成的糖皮质激素，具有代谢、抗炎和抗过敏特性，有潜力用于眼科的眼炎症研究。
T0094	Budesonide Entocort,Pulmicort,布地奈德,Rhinocort	Glucocorticoid Receptor	Endocrinology/Hormones
	Budesonide (Pulmicort) 是吸入型糖皮质类固醇，是一种口服具有活性的糖皮质激素受体激动剂。它能够减小肺部肿瘤的体积，逆转 DNA 低度甲基化，调节基因的 mRNA 表达。它是能够用于哮喘的抗炎药。
T25360	Eclazolast RHC2871,RHC-2871,REV2871,REV 2871,RHC 2871	Others	Others
	Eclazolast (RHC 2871) 是一种亲脂性抗过敏化合物，在肥大细胞模型中抑制介质释放。Eclazolast 通过在细胞内只影响与Fc(epsilon)RI 相关的直接过程而抑制细胞外分泌。Eclazolast 的效果高度依赖于触发细胞的抗原浓度。
T41303	Isoflupredone Delta-Fluorocortisone,Isoflupredona,异氟泼尼松,Isoflupredonum,9-Fluoroprednisolone	Others	Others
	Isoflupredone (Isoflupredonum) 是一种合成的皮质类固醇，通过与动物 (如马) 的糖皮质激素和矿皮质激素受体结合抑制炎症细胞和抑制炎症介质的表达在生物体内发挥作用。Isoflupredone 具有抗炎和免疫抑制作用，可应用于治疗各种肌肉骨骼、过敏性和全身炎症性疾病。
T26341	Y 9000 Y9000,Y-9000
	Y 9000 has anti-allergic activity.
T25605	Lambertianic acid
	Lambertianic acid is a bioactive chemical that has anti-allergic and antibacterial effects.
T26582	AIM-102
	AIM-102, a nonsteroidal, immune modulating, anti-inflammatory drug, is used potentially for the treatment of allergic asthma.
T63766	MrgprX2 antagonist-7
	MrgprX2 antagonist-7 是一种抗过敏剂，具有明显的抗过敏效果，能够抑制肥大细胞脱颗粒。
T30927	CI-959 free acid UNII-Y8M8A93SU8
	CI-959 Free Acid is an orally effective inhibitor of cell activation in vitro and in animal models and also has anti-allergic/anti-inflammatory properties.
T69301	Picumast dihydrochloride
	Picumast dihydrochloride is a prophylactically active anti-allergic compound which combines inhibition of mediator release and action. The activity profile of PDH differs clearly from that of known prophylactic anti-allergic drugs such as DSCG and ketotifen.
T34307	Revenast
	Revenast 是一种强效抗过敏新化合物。该物质能在人体中迅速而广泛地代谢，从而产生抗过敏作用。
T21388	Emedastine Difumarate Rapimine,DSSTox_CID_26911,AL-3432A,富马酸依美斯汀,KB-2413,Emedastine fumarate,KB 2413
	Emedastine Difumarate is a selective histamine H1 receptor antagonist with anti-allergic activity, prescribed for allergic conjunctivitis. Upon ocular administration, emedastine causes a dose-dependent inhibition of histamine-stimulated vascular permeabil
T27388	FR-A 19 FR-A-19,FRA19
	FR-A 19, a Histamine H2 agonist, inhibits the release of IgE-mediated human basophil histamine in a nanomolar range. It has additional potent anti-allergic properties.
T38127	pNPS-DHA
	pNPS-DHA is an arylamide derivative of docosahexaenoyl ethanolamide that has anti-allergic activity.1It inhibits degranulation of RBL-2H3 mast cells (IC50= 15 μM).pNPS-DHA (1,000 mg/kg) inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) in mice. 1.Kim, I.-H., Kanayama, Y., Nishiwaki, H., et al.Structure-activity relationships of fish oil derivatives with anti-allergic activity in vitro and in vivoJ. Med. Chem.62(21)9576-9592(2019)
T26628	Andolast CR2039,CR-2039,CR 2039
	Andolast, also known as CR-2039, an anti-allergic agent for the treatment of bronchial asthma, chronic obstructive pulmonary disease (COPD). Andolast acts at different cellular levels to inhibit immunoglobulin E synthesis. Andolast proved to be significan
T60498	Chlorpheniramine
	Chlorpheniramine 是一种 H1 抗组胺药，用于治疗 IgE 介导的炎症，通常用于治疗过敏性疾病。
T63825	Antiallergic agent-1
	Antiallergic agent-1 是 Src 家族激酶抑制剂，是一种新的有价值的先导化合物，具有作为抗过敏剂的潜力。
T15503	HQL-79	Others	Others
	HQL-79 is a selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor. It inhibits the synthesis of PGD2 and acts as an anti-allergic agent (Kd: 0.8 μM and IC50: 6 μM). It also shows no obvious effect on COX-1, COX-2, m-P
T73972	Fexofenadine Impurity F
	Fexofenadine Impurity F 是 Fexofenadine 的杂质。 Fexofenadine 是一种H1R 拮抗剂，可用于研究季节性过敏性鼻炎和慢性特发性荨麻疹。
T76320	FIZZ-1 (32-51) (mouse)
	FIZZ-1 (32-51) (mouse) 是一种富含半胱氨酸的分泌性蛋白，主要在过敏性气道炎症中被巨噬细胞、支气管上皮细胞及II型肺泡上皮细胞高度表达，具有对肺成纤维细胞的抗凋亡功能，广泛应用于过敏性肺炎的研究领域。
T60590	Chloropyramine
	Chloropyramine 是竞争性可逆 H1 受体拮抗剂，可用于过敏性疾病的研究，例如结膜炎和支气管哮喘。Chloropyramine 表现出抗乳腺癌活性。
T62691	Syk Inhibitor II dihydrochloride dihydrate
	Syk Inhibitor II dihydrochloride dihydrate 是一种高度选择性的、有效的、ATP 竞争性 Syk 抑制剂 (IC50: 41 nM)。Syk Inhibitor II dihydrochloride dihydrate 抑制 RBL 细胞释放 5-HT (IC50: 460 nM)，对其他激酶的作用较弱。Syk Inhibitor II dihydrochloride dihydrate 表现出抗过敏作用。
T74118	Roxatidine
	Roxatidine 是 Roxatidine acetate 的活性代谢产物，是组胺 H2受体拮抗剂。Roxatidine 是抗溃疡药，抑制组胺释放（从而抑制质子分泌）并抑制炎症和血管生成的重要标志物 VEGF-1 的产生。具有抗过敏性炎症作用。
T36713	Streptochlorin
	Streptochlorin is a bacterial metabolite originally isolated from Streptomyces sp. SF2583 that has diverse biological activities, including antiangiogenic, antiproliferative, and anti-allergic properties. It inhibits TNF-α-induced NF-κB transcriptional activity and decreases proliferation of human umbilical vein endothelial cells (HUVECs) when used at concentrations ranging from 5 to 20 μM. Streptochlorin (12 μg/ml) decreases viability of, as well as induces apoptosis and increases the productio...
T73666	Proglumetacin
	Proglumetacin 是一种口服有效的环加氧酶 (cyclo-oxygenase) 抑制剂。Proglumetacin 可以抑制 SARS-CoVMpro(新冠病毒的主要蛋白酶)，其 AC50为 8.9 μM。Proglumetacin 具有抗炎活性，可用于炎症(如类风湿关节炎、过敏性气囊炎)的研究。
T60496	Ketorolac hemicalcium
	Ketorolac (RS37619) hemicalcium 是一种非选择性的 COX 抑制剂，对 COX-1 的 IC50 为 20 nM，对 COX-2 的 IC50 为 120 nM。 Ketorolac hemicalcium 是一种非甾体类抗炎药 (NSAID)，可用作 0.5% 滴眼液，用于研究过敏性结膜炎、黄斑囊样水肿、术中瞳孔缩小和术后眼部炎症和疼痛等。 Ketorolac hemicalcium 也是一种可用于癌症研究的 DDX3 抑制剂 [1] [4]。
T38350	TAS 205
	TAS 205 is an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS; IC50= 55.8 nM).1It is selective for H-PGDS over lipocalin-type PGDS (L-PGDS) at 100 μM, as well as over enzyme and receptor panels at 10 μM. TAS 205 inhibits production of prostaglandin D2induced by A23187 in KU812 human and RBL-2H3 rat basophils with IC50values of 78.3 and 181.3 nM, respectively. It inhibits ovalbumin-induced nasal lavage fluid eosinophil infiltration and late-phase nasal obstruction in an ovalbumin-sens...

化合物

Cat.No: T5424

Synonym: 依托柳胺,Ethosalamide

Target: Others

Fluticasone furoate

Cat.No: T21404

Synonym: Veramyst,Allermist,Avamys,糠酸氟替卡松,Fluticasone furoate

Target: Glucocorticoid Receptor

Syk Inhibitor II

Cat.No: T4348

Target: 5-HT Receptor, Syk

Cat.No: T5449

Synonym: F 10126,L 0042,巴马司特

Target: Proton pump

PDK4-IN-1 hydrochloride

Cat.No: T12412L

Target: Apoptosis, PDK

Clemastine fumarate

Cat.No: T0147

Synonym: HS-592 (fumarate),富马酸氯马斯汀,Meclastine fumarate,Meclastine (fumarate)

Target: Autophagy, Histamine Receptor

Fluticasone (propionate)

Cat.No: T0188

Synonym: 丙酸氟替卡松,CCI-187881,氟替卡松丙酸酯,Fluticasone propionate

Target: Glucocorticoid Receptor, Virus Protease, Estrogen/progestogen Receptor, Phospholipase, Endogenous Metabolite

Lodoxamide tromethamine

Cat.No: T15772

Synonym: U-42585E

Target: Histamine Receptor

Cat.No: T7812

Synonym: MTCC,阿扎司特,WP-871

Target: Others

Cat.No: T27159

Synonym: DF1111301,DF 1111301

Target: Platelet aggregation, Histamine Receptor

Cat.No: T10945

Target: Others

Mometasone furoate

Cat.No: T1531

Synonym: 糠酸莫美他松,糠酸莫米松,Sch32088

Target: Glucocorticoid Receptor

Alclometasone dipropionate

Cat.No: T21361

Synonym: Vaderm,Sch 22219,Aclovate,Delonal

Target: Others

Lodoxamide ethyl

Cat.No: T68094

Target: Others

Cat.No: T0298

Synonym: 茶苯海明,Dramamine,Chloranautine,乘晕宁,Vomex A

Target: Histamine Receptor

Cat.No: T11581

Target: Others

Cat.No: T50001

Synonym: ethyl 2-amino-6-benzyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylate,替诺立定

Target: P450

Cat.No: T3979

Synonym: LY188695,依美斯汀,Emadine

Target: Histamine Receptor

(+)-Dropropizine

Cat.No: T0217L

Synonym: (+)-Dropropizine,左羟丙哌嗪

Target: Histamine Receptor

Cat.No: T0219

Synonym: 伐地考昔,代他考昔,SC 65872

Target: COX

Cat.No: T0977

Synonym: Gimeracil,6α-Methyl-11β-hydroxyprogesterone,6A-甲基-11B-羟孕酮,甲羟松

Target: Glucocorticoid Receptor, Others

Cat.No: T0094

Synonym: Entocort,Pulmicort,布地奈德,Rhinocort

Target: Glucocorticoid Receptor

Cat.No: T25360

Synonym: RHC2871,RHC-2871,REV2871,REV 2871,RHC 2871

Target: Others

Cat.No: T41303

Synonym: Delta-Fluorocortisone,Isoflupredona,异氟泼尼松,Isoflupredonum,9-Fluoroprednisolone

Target: Others

Cat.No: T26341

Synonym: Y9000,Y-9000

Lambertianic acid

Cat.No: T25605

Cat.No: T26582

MrgprX2 antagonist-7

Cat.No: T63766

CI-959 free acid

Cat.No: T30927

Synonym: UNII-Y8M8A93SU8

Picumast dihydrochloride

Cat.No: T69301

Cat.No: T34307

Emedastine Difumarate

Cat.No: T21388

Synonym: Rapimine,DSSTox_CID_26911,AL-3432A,富马酸依美斯汀,KB-2413,Emedastine fumarate,KB 2413

Cat.No: T27388

Synonym: FR-A-19,FRA19

Cat.No: T38127

Cat.No: T26628

Synonym: CR2039,CR-2039,CR 2039

Chlorpheniramine

Cat.No: T60498

Antiallergic agent-1

Cat.No: T63825

Cat.No: T15503

Target: Others

Fexofenadine Impurity F

Cat.No: T73972

FIZZ-1 (32-51) (mouse)

Cat.No: T76320

Cat.No: T60590

Syk Inhibitor II dihydrochloride dihydrate

Cat.No: T62691

Cat.No: T74118

Cat.No: T36713

Cat.No: T73666

Ketorolac hemicalcium

Cat.No: T60496

Cat.No: T38350

Cat. No.	Product Name	Target	Signaling Pathways
T12651	Rabdosiin (+)-Rabdosiin	Others	Others
	Rabdosiin ((+)-Rabdosiin) 是一种分离自 Rabdosia japonicaHara 中的咖啡酸四聚体，具有抗过敏、抗 HIV 和抑制 DNA 拓扑异构酶作用。
T2982	Xanthone Genicide,呫吨酮,氧杂蒽酮,Xanthenone,Benzophenone oxide	Apoptosis; Others; Influenza Virus; Antibacterial; Antifungal	Apoptosis; Microbiology/Virology; Others
	Xanthone (Xanthenone) 是一种从山竹果中分离得到的天然产物，具有抗炎，抗氧化，抗肿瘤，抗过敏，抗细菌，抗真菌和抗病毒活性。在癌变的不同阶段可控制细胞分裂和生长，凋亡，炎症和转移。
T2902	Costunolide Costus lactone,NSC 106404,Costunolid,(+)-Costunolide,木香烃内酯	Apoptosis; Endogenous Metabolite; Telomerase	Apoptosis; DNA Damage/DNA Repair; Metabolism
	Costunolide (Costus lactone) 是一种天然的倍半萜内酯，具有抗氧化、抗炎、抗过敏、骨重塑、神经保护、促进毛发生长、抗癌和抗糖尿病的特性，可诱导乳腺癌细胞周期阻滞和凋亡。
T2S0504	Ilexoside D	Others	Others
	Ilexoside D has ant-allergic, and anti-coagulant activities, it shows anti-tissue factor activity as well as the antithrombotic activity.
T5666	Dipotassium glycyrrhizinate	Virus Protease	Microbiology/Virology
	Dipotassium glycyrrhizinate 是一种具有抗过敏和抗炎活性的阴离子表面活性剂。
T3872	Nodakenin 紫花前胡苷,(+)-Marmesinin	AChE	Neuroscience
	Nodakenin ((+)-Marmesinin) 是一种Peucedanum decursivum Maxim 根中的主要香豆素苷。它能够抑制乙酰胆碱酯酶活性，IC50=84.7 μM。
T4S2164	Narirutin Naringenin-7-O-rutinoside,Isonaringin,芸香柚皮苷,柚皮芸香苷	Others; Antibacterial	Microbiology/Virology; Others
	Narirutin (Naringenin-7-O-rutinoside) 是从Citrus unshiu 中分离的活性成分之一，具有抗氧化和抗炎活性。它是一种具有抗结核效力的shikimate 激酶抑制剂。
TMA1570	Sappanone A	NF-κB; Nrf2	Immunology/Inflammation; NF-κB
	Sappanone A 是一种高异黄烷酮，通过调节 Nrf2 和 NF-κB 表现出抗炎作用。Sappanone A 可以减轻卵清蛋白引起的哮喘中的过敏性气道炎症。
T2S2362	Dehydrocorydaline nitrate 去氢延胡索甲素硝酸盐,硝酸脱氢紫堇碱	BCL; Others; PARP; p38 MAPK; Caspase; Parasite; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK; Microbiology/Virology; Others; Proteases/Proteasome
	Dehydrocorydaline nitrate 是生物碱。Dehydrocorydaline 调节 Bax，Bcl-2蛋白表达，激活 caspase-7，caspase-8，并使 PARP 失活。它能增强 p38 MAPK 活化，具有抗炎、抗癌、抗疟疾等功效。
TN1088	3,5,6,7,8,3',4'-Heptemthoxyflavone 3,3',4',5,6,7,8-heptamethoxyflavone,3,5,6,7,8,3',4'-七甲氧基黄酮	Others	Others
	3,5,6,7,8,3',4'-Heptemthoxyflavone 是来自蜜柑皮中的黄酮，具有抗肿瘤起始活性和抗神经炎症作用。它能通过 cAMP/ERK/CREB 信号诱导脑源性神经营养因子表达，降低 C6 细胞磷酸二酯酶活性。它能抑制胶原酶的活性，增加人真皮成纤维细胞新生细胞中 I 型前胶原含量。
TN1040	Skullcapflavone II	COX; Antibacterial; TGF-beta/Smad	Immunology/Inflammation; Microbiology/Virology; Neuroscience; Stem Cells
	Skullcapflavone II 是从黄芩中提取的黄酮，具有抗炎作用。它对 M. aurum 和 M. bovisBCG 具有较强的抗菌活性。它还调节破骨细胞的分化、存活和功能。
TN1516	Cnidicin 蛇床素,4,9-双[(3-甲基-2-丁烯-1-基)氧基]-7H-呋喃并[3,2-G][1]苯并吡喃-7-酮	NOS; NO Synthase	Immunology/Inflammation
	Cnidicin 是一种香豆素，对肥大细胞脱颗粒及 RAW 264.7 细胞产生一氧化氮具有抑制作用。
T4S1943	Kirenol 奇壬醇,奇任醇,Kirel	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	Kirenol (Kirel) 是分离自 Siegesbeckia orientalis 中的，具有抗氧化、抗炎、抗过敏、抗关节炎活性，可用于缓解疼痛的研究。
T6S0117	Avicularin Fenicularin,扁蓄苷	ERK	MAPK
	Avicularin (Fenicularin) 具有抗过敏、抗炎、保肝、抗氧化、抗肿瘤等活性。它能通过调节 NF-κB(p65)、COX-2 和 PPAR-γ 的活性来改善人类肝细胞癌。在 LPS 刺激的 RAW 264.7 巨噬细胞中，它通过抑制 ERK 信号通路产生抗炎活性。
TN1470	Cassiaside B2 决明子苷B2	Phosphatase; MAO; 5-HT Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Cassiaside B2 是蛋白酪氨酸磷酸酶1B (PTP1B) 和人单胺氧化酶A (hMAO-A) 的抑制剂。Cassiaside B2是 5-HT2C 受体的激动剂，具有抗过敏活性。Cassiaside B2 是萘吡喃酮参比提取物（NRE）的有效成分之一。
TN1712	Gossypin	NF-κB; S6 Kinase	MAPK; NF-κB; PI3K/Akt/mTOR signaling
	Gossypin 是一种从Hibiscus vitifolius 中分离得到的黄酮，能够抑制NF-κB 和 NF-κB 的调节基因表达。在小鼠原代骨髓细胞和 RAW264.7 细胞中，它也可抑制 RANKL 诱导的破骨细胞形成。它具有抗氧化、抗炎、抗癌、抗衰老、抗糖尿病和保护肝脏的活性。
T17214	Valencene NSC 148969,NSC-148969,NSC148969	Others; Antioxidant; NF-κB	NF-κB; Others; oxidation-reduction
	Valencene (NSC-148969) 是一种从 Cyperus rotundus 中分离出来的倍半萜类化合物，是柑橘类水果和柑橘类衍生气味的香气成分。ValenceneValencene 具有抗过敏、抗炎、抗黑色素生成、和抗氧化活性。通过阻断 NF-κB 通路，Valencene 通过阻断 NF-κB 通路抑制 Th2 趋化因子和促炎性趋化因子的过度表达。
T5S1285	(+)-(3R,8S)-Falcarindiol Falcarindiol,镰叶芹二醇	Others	Others
	(+)-(3R,8S)-Falcarindiol 是一种从胡萝卜中得到的聚乙炔，有抗炎、抗肿瘤和抗脂质过氧化活性。它具有抗分歧杆菌作用，对Mycobacterium tuberculosisH37Ra 的 MIC 和 IC50值分别为 24 μM 和 6 μM。
T4518	Licochalcone D	ERK; NF-κB	MAPK; NF-κB
	Licochalcone D 是一种 NF-κB p65的有效抑制剂，是一种存在于 Glycyrrhiza inflate 中的黄酮类化合物，具有抗氧化、抗炎、抗癌等作用。
T5S1286	(+)-Columbianetin 二氢山芹醇,(S)-Columbianetin,Columbianetin	Antifungal	Microbiology/Virology
	(+)-Columbianetin ((S)-Columbianetin) 是 Columbianetin 的异构体。其中Columbianetin 是一种植物抗毒素，与芹菜贮藏过程中对病原体的抗性有关，具有良好的抗真菌和抗炎作用。
T3S1612	kuwanon G 桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G	Phosphatase; Antibacterial; Bombesin Receptor; AChR; AChE; Glucosidase	GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
	Kuwanon G (Moracenin B) 是一种从桑树中得到的黄酮类蛙皮素受体拮抗剂，具有杀菌作用。
TN5062	Stigmast-4-ene-3,6-dione
	Stigmast-4-ene-3,6-dione has anti-inflammatory and anti-allergic properties.
T39570	Cycloartenyl ferulate Cycloartenolferulate,Cycloartenolferulicacidester,环木菠萝烯醇阿魏酸酯
	Cycloartenyl ferulate (also known as cycloartenol ferulate) is a representative triterpene alcohol with diverse biological properties, such as antioxidant, anti-allergic, anti-inflammatory, and anticancer activities.
TN3483	Bakkenolide D	IL Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Bakkenolide D has anti-allergic effect, it and bakkenolide D demonstrates inhibitory effect on the trachea contraction induced by histamine in vitro, they have obvious anti-histamine activities.
TN4429	Leucodin	MMP; TNF	Apoptosis; Proteases/Proteasome
	Leucodin shows high anti-hypercholesterolemic potential. Leucodin may have anti-allergic activity, it shows a potent inhibitory activity upon the beta-hexosaminidase release from RBL-2H3 cells in a dose-dependent manner with IC50 of 80 microM.
TN3513	Bis-5,5-nortrachelogenin	Others	Others
	Bis-5,5-nortrachelogenin has anti-allergic activity, it inhibited NO production with IC50 value of 48.6 microM.
TN3836	Desacetylmatricarin	Others	Others
	Desacetylmatricarin has anti-allergic property, it shows a potent inhibitory activity upon the beta-hexosaminidase release from RBL-2H3 cells in a dose-dependent manner and the IC50 of 7.5 microM.
TN1845	Kushenol N	Others	Others
	Kushenol N may have anti-allergic activity, it demonstrates significant inhibition of the release of beta-hexosaminidase from cultured RBL-2H3 cells .
TN3936	ent-16-Kaurene-3beta,15beta,18-triol	Others	Others
	ent-16-Kaurene-3beta,15beta,18-triol, ent-16-kaurene-3beta,15beta-diol,abbeokutone,and helioscopinolide A possess appreciable anti-allergic activities in RBL-2H3 cells model with IC50 values ranging from 22.5 to 42.2 microM.
TN4392	Koaburaside	IL Receptor; TNF; Influenza Virus	Apoptosis; Immunology/Inflammation; Microbiology/Virology
	Koaburaside exhibits antioxidant activity with an IC50 value of 9.0μM, it shows weak inhibitory activity against influenza A neuraminidase. Koaburaside may have anti-allergic inflammatory activity, it can suppress histamine release from mast cells.
TN5033	Skullcapflavone I	IL Receptor; Caspase; Prostaglandin Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; Proteases/Proteasome
	Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dependent manner. Skullcapflavone I se
TN3325	9-O-Feruloyl-5,5'-dimethoxylariciresinol	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	(+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol may have anti-allergic inflammatory effect, it can inhibit release of histamine from mast cells. It shows cytotoxicity against a small panel of human tumor cell lines, with ED50 values of 9.86 to approxi
TN2511	Britannilactone diacetate 1,6-O,O-Diacetylbritannilactone	IL Receptor; PARP; ROS; MAPK; Caspase; JAK; JNK; STAT	Angiogenesis; Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; JAK/STAT signaling; MAPK; Proteases/Proteasome; Stem Cells
	1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airway disease as a lead compound. OODBL has anti-asthmatic activity, it reduces leukotriene C4 pro
TN3870	Iriflophenone 2-O-Rhamnoside Dimethylmatairesinol	Others	Others
	Dimethylmatairesinol can reduce the amount of Immunoglobulin E (IgE) secreted by human myeloma U266 cells, it has potential as an anti-allergic agent. Dimethylmatairesinol also exhibits significant cytotoxicity against three human tumor cells(A-549 lung c
TN4489	Manassantin A	ERK; cAMP; TNF; NF-κB; MAPK; COX; HIF; Prostaglandin Receptor; JNK; STAT	Angiogenesis; Apoptosis; Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; JAK/STAT signaling; MAPK; Neuroscience; NF-κB; Stem Cells
	Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effects might be associated with COX/PGE2 stimulation, inhibition of iNOS production and NF-ÎºB act

天然产物

Cat.No: T12651

Synonym: (+)-Rabdosiin

Target: Others

Cat.No: T2982

Synonym: Genicide,呫吨酮,氧杂蒽酮,Xanthenone,Benzophenone oxide

Target: Apoptosis, Others, Influenza Virus, Antibacterial, Antifungal

Cat.No: T2902

Synonym: Costus lactone,NSC 106404,Costunolid,(+)-Costunolide,木香烃内酯

Target: Apoptosis, Endogenous Metabolite, Telomerase

Cat.No: T2S0504

Target: Others

Dipotassium glycyrrhizinate

Cat.No: T5666

Target: Virus Protease

Cat.No: T3872

Synonym: 紫花前胡苷,(+)-Marmesinin

Target: AChE

Cat.No: T4S2164

Synonym: Naringenin-7-O-rutinoside,Isonaringin,芸香柚皮苷,柚皮芸香苷

Target: Others, Antibacterial

Cat.No: TMA1570

Target: NF-κB, Nrf2

Dehydrocorydaline nitrate

Cat.No: T2S2362

Synonym: 去氢延胡索甲素硝酸盐,硝酸脱氢紫堇碱

Target: BCL, Others, PARP, p38 MAPK, Caspase, Parasite, Autophagy

3,5,6,7,8,3',4'-Heptemthoxyflavone

Cat.No: TN1088

Synonym: 3,3',4',5,6,7,8-heptamethoxyflavone,3,5,6,7,8,3',4'-七甲氧基黄酮

Target: Others

Skullcapflavone II

Cat.No: TN1040

Target: COX, Antibacterial, TGF-beta/Smad

Cat.No: TN1516

Synonym: 蛇床素,4,9-双[(3-甲基-2-丁烯-1-基)氧基]-7H-呋喃并[3,2-G][1]苯并吡喃-7-酮

Target: NOS, NO Synthase

Cat.No: T4S1943

Synonym: 奇壬醇,奇任醇,Kirel

Target: Wnt/beta-catenin

Cat.No: T6S0117

Synonym: Fenicularin,扁蓄苷

Target: ERK

Cat.No: TN1470

Synonym: 决明子苷B2

Target: Phosphatase, MAO, 5-HT Receptor

Cat.No: TN1712

Target: NF-κB, S6 Kinase

Cat.No: T17214

Synonym: NSC 148969,NSC-148969,NSC148969

Target: Others, Antioxidant, NF-κB

(+)-(3R,8S)-Falcarindiol

Cat.No: T5S1285

Synonym: Falcarindiol,镰叶芹二醇

Target: Others

Cat.No: T4518

Target: ERK, NF-κB

(+)-Columbianetin

Cat.No: T5S1286

Synonym: 二氢山芹醇,(S)-Columbianetin,Columbianetin

Target: Antifungal

Cat.No: T3S1612

Synonym: 桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G

Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase

Stigmast-4-ene-3,6-dione

Cat.No: TN5062

Cycloartenyl ferulate

Cat.No: T39570

Synonym: Cycloartenolferulate,Cycloartenolferulicacidester,环木菠萝烯醇阿魏酸酯

Cat.No: TN3483

Target: IL Receptor, Histamine Receptor

Cat.No: TN4429

Target: MMP, TNF

Bis-5,5-nortrachelogenin

Cat.No: TN3513

Target: Others

Desacetylmatricarin

Cat.No: TN3836

Target: Others

Cat.No: TN1845

Target: Others

ent-16-Kaurene-3beta,15beta,18-triol

Cat.No: TN3936

Target: Others

Cat.No: TN4392

Target: IL Receptor, TNF, Influenza Virus

Skullcapflavone I

Cat.No: TN5033

Target: IL Receptor, Caspase, Prostaglandin Receptor

9-O-Feruloyl-5,5'-dimethoxylariciresinol

Cat.No: TN3325

Target: IL Receptor, TNF

Britannilactone diacetate

Cat.No: TN2511

Synonym: 1,6-O,O-Diacetylbritannilactone

Target: IL Receptor, PARP, ROS, MAPK, Caspase, JAK, JNK, STAT

Iriflophenone 2-O-Rhamnoside

Cat.No: TN3870

Synonym: Dimethylmatairesinol

Target: Others

Cat.No: TN4489

Target: ERK, cAMP, TNF, NF-κB, MAPK, COX, HIF, Prostaglandin Receptor, JNK, STAT

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼