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Targets Recommended: ASK GSK-3

611

抑制剂 & 化合物

45

天然产物

1

化合物库

2

TargetMol 试剂盒

56

重组蛋白

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Cat. No. Product Name
L1310 细胞骨架化合物库

759 compounds
759 种细胞骨架相关的化合物,可以用于高通量和高内涵筛选;

化合物库

细胞骨架化合物库
Cat.No: L1310
Compounds: 759
Cat. No. Product Name Form Specificity Of Inhibition
CL0063 Cytoskeleton pathway inhibitor kit

Cytoskeleton pathway inhibitor kit

CL0092 GSK-3 inhibitor kit

GSK-3 inhibitor kit

TargetMol 试剂盒

Cytoskeleton pathway inhibitor kit
Cat.No: CL0063
GSK-3 inhibitor kit
Cat.No: CL0092
Cat. No. Product Name Target Signaling Pathways
T69596 SK-575

SK-575 is a Highly Potent and Efficacious Proteolysis-Targeting Chimera Degrader of PARP1 for Treating Cancers. SK-575 potently inhibits the growth of cancer cells bearing BRCA1/2 mutations and induces potent and specific degradation of PARP1 in various human cancer cells even at low picomolar concentrations. SK-575 achieves durable tumor growth inhibition in mice when used as a single agent or in combination with cytotoxic agents, such as temozolomide and cisplatin.
T24797 SK609 HCl

SK-609 HCl,SK609 hydrochloride,SK 609 HCl,SK 609 hydrochloride,SK-609 hydrochloride

SK609 HCl is a selective dopamine D3 receptor agonist. It also has atypical signaling properties.
T34650 SK&F 107461

SK&F107461,SK&F-107461

F 107461 is a hydroxyethylene dipeptide isostere.
T12928 SK33

Androgen Receptor Endocrinology/Hormones
SK33 是一种有效的组织选择性抗雄激素药物,是一种肌醇类似物,能够降低雄激素受体 (AR) 的转录活性。
T24798 SK-7041

SK 7041

SK-7041 is an effective HDAC inhibitor that acts by preferentially inhibiting class I HDAC1 and HDAC2.
T26191 SK&F 104976

SK&F104976,Skf104976,Skf 104976,SK&F-104976,Skf-104976

SK&F 104976 is a 32-carboxylic acid derivative of lanosterol. It was found to be a potent lanosterol 14 alpha-demethylase (14 alpha DM) inhibitor.
T7524 Metiamide

甲硫米特,SK&F 92058

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Metiamide (SK&F 92058) 是一种组胺H2受体拮抗剂。
T29067 Upacicalcet

PLS-240,SK-1403,AJT-240

Calcium Channel Membrane transporter/Ion channel; Metabolism
Upacicalcet (AJT-240) 是一种静脉内拟钙剂,是一种可用于人血液透析的 SHPT, 通过直接作用于甲状旁腺细胞膜钙敏感受体来抑制过量的甲状旁腺激素 (PTH) 分泌,从而降低血液中的 PTH 水平。 3 Upacicalcet 是钙敏感受体的正变构调节剂,可预防大鼠腺嘌呤诱导的继发性甲状旁腺功能亢进模型中的血管钙化和骨骼疾病。
T26644 Apomine

SK&F-99085,APB-231-A2,APB-231-A-2,SR-9223i,SK&F-99085,SR-45023A

HMG-CoA Reductase Metabolism
Apomine (SR-9223i) 是一种 HMG-CoA-还原酶抑制剂,可在体外促进骨髓瘤细胞的凋亡,并与体内骨髓瘤的调节有关。 Apomine 加速 3-羟基-3-甲基戊二酰-CoA 还原酶的降解并刺激低密度脂蛋白受体活性。 Apomine 通过下调 3-羟基-3-甲基戊二酰-CoA 还原酶来增强洛伐他汀对骨髓瘤细胞的抗肿瘤作用。
T7133 Anagliptin

SK-0403,阿拉格列汀

Proteasome; DPP-4 Proteases/Proteasome; Ubiquitination
Anagliptin (SK-0403) 是一种选择性的二肽酰肽酶 4 抑制剂,IC50=3.8 nM,对 DPP-8/9 的选择性相对较弱,IC50分别为 68 和 60 nM。
T34651 SK&F 108361

Skf-108361,SK&F-108361,Skf 108361,SK&F108361,Skf108361

SK&F 108361 is a symmetric diol that binds HIV-1 protease symmetrically.
T20641 Propagermanium

Dipropanoic acid germanium sequioxide,SK-818,Ge 132,二羧乙基三氧化二锗,Ge132,SK 818,Ge-132

Others Others
Propagermanium (Ge132) 是一种锗的有机金属化合物,在日本已被用作治疗慢性乙型肝炎的药物。
T34652 SK&F 39728-A

SK&F39728-A,SK&F 1-39728,SK&F-39728-A,Skf 39728-A

SK&F 39728-A is a bioactive chemical.
T24795 SK&F 103784

Skf 103784,Skf-103784,Skf103784

SK&F 103784 is a vasopressin antagonist.
TQ0126 Mirodenafil dihydrochloride

SK-3530 dihydrochloride,米罗那非二盐酸盐

PDE Metabolism
Mirodenafil dihydrochloride 是一种磷酸二酯酶5(PDE-5)抑制剂,可作用于勃起功能紊乱的研究。
T28787 SK&F-95601

SK&F 95601,SKF95601,SKF 95601,SKF-95601

F-95601 is a proton pump inhibitor.
T26190 SK&F 106760

SK&,F-106760,SKF 106760,SKF-106760,F106760,SKF106760,F 106760

SKF 106760 is used as a glycoprotein IIb/IIIa antagonist.
T41273 Phen Green SK diacetate

Phen Green SK diacetate 在生命科学相关研究中具有广泛的应用。
T28788 SK-216

SK216.Plasminogen activator inhibitor-1 (PAI-1) inhibitor

SK-216 is a specific PAI-1 inhibitor. SK-216 reduced the extent of angiogenesis in the tumors and inhibited VEGF-induced migration and tube formation by human umbilical vein endothelial cells in vitro. SK-216 reduced the degree of bleomycin-induced pulmon
T24796 SK&F 107260

Skf107260,Skf-107260,Skf 107260

SK&F 107260 is an RGD-containing peptide. It is a potent GP IIb/IIIa antagonist and a vitronectin antagonist.
T23761 Atiprimod dimaleate

SK&F-106615,SK&F 106615,SK&F106615

Atiprimod Dimaleate is a JAK2 inhibitor.
T70618 SK609

SK609 is a selective dopamine D3 receptor agonist which significantly improves the performance of the impaired paw and normalizes the bilateral asymmetry associated with the hemiparkinson rat.
T35203 Xylonidine

SK&F-35866,SK&F35866,SK&F 35866

Xylonidine is a biochemical.
T28796 SKI2852

SK I2852,SKI-2852

SKI2852 is a highly Potent, selective, and orally bioavailable inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1). hHSD1 IC50 = 2.9nM; mHSD1 IC50 = 1.6nM.
T70283 SK 946

SK 946 is a cognition activator.
T33740 NSC 157449

SK&F-83589,SK&F 83589,NSC157449,NSC-157449

NSC 157449 is a bioactive chemical.
T23883 Chlorasquin

Ccnsc-529,861,Ccnsc 529,861,SK 29861,Ccnsc529,861,SK-29861

Chlorasquin is a dihydrofolate reductase inhibitor.
T74558 SK-575-NEG

SK-575-NEG(化合物28)是SK-575的甲基化对应物,通过对SK-575中的哌啶-2,6-二酮氨基进行甲基化合成而得,用作对照化合物。SK-575-NEG强效结合PARP1,IC50值仅为2.64 nM。在1 μM浓度下,SK-575-NEG对MDA-MB-436和Capan-1细胞中PARP1的降解完全无效。
T81151 SK-MLCK M13

SK-MLCK M13,作为具生物活性的肽类化合物,代表着钙调蛋白(CaM)靶标蛋白的CAM结合域,其中CaM为广泛存在的Ca2+结合蛋白。
T16079 Mirodenafil

米罗那非,SK3530

PDE Metabolism
Mirodenafil 是一种磷酸二酯酶5(PDE-5)抑制剂,可用于勃起功能紊乱的研究。
T25453 Glaspimod

F 107647,SK&,F-107647,F107647

Glaspimod is a synthetic hematoregulatory peptide. It shares biological and/or modulatory activities with natural hematopoetic cytokines.
T33787 Olaflur

SKF 38095,GA 297,SK&F 38095

Olaflur is a compound that prevents dental caries.
T31364 Dehydelone

KOS1584,SK-10088,KOS-1584,R-1645,SK10088,R1645

Dehydelone(KOS-1584, R-1645, SK-10088) is a microtubule stabilizer that may be used in the treatment of non-small cell lung cancer.
T32834 Lobendazole

SK&F 24529,SKF 24529,NSC-42044,NSC42044,NSC 42044

Lobendazole is a metabolite of thiophanate.
T28794 SKF-97574 HCl

SKF97574,SKF-97574,B-9937-051,BY 574,SKF 97574,SK&F-97574

SKF-97574 is proton pump inhibitor.
T68818 Icotidine

Icotidine is an antagonist of histamine at both H1 and H2 receptors.
T34653 SK1071

SK1071 is a novel migrastatin analogs, which demonstrated improved performance over migrastatin, with nanomolar IC50 values in chamber cell migration assays with tumor cells and human umbilical vein endothelial cells (HUVECs), and in wound healing assays.
T9033 BTYNB

MDK6620,BTYNB IMP1 Inhibitor

Others; c-Myc; NF-κB Cell Cycle/Checkpoint; NF-κB; Others
BTYNB (MDK6620) 是IMP1结合 c-Myc mRNA 的有效选择性抑制剂,IC50为 5 μM。它下调 β-TrCP1 mRNA 并减少NF-κB 的激活。它通过损害 IGF2 mRNA 结合蛋白 1 结合来破坏这种增强子功能,可用于癌症研究。
T71174 PBT434 HBr

PBT434 is a novel, brain-penetrant, small molecule inhibitor of α-synuclein aggregation. In transgenic animal models of Parkinson disease (A53T) and MSA (PLP-α-Syn), PBT434 reduced α-synuclein aggregation, preserved neurons and improved motor function. Glial cell inclusions were also reduced in a murine MSA model. PBT434 is thought to act by redistributing reactive iron across membranes, thereby blocking intracellular protein aggregation and oxidative stress. The affinity of PBT434 for iron is g...
T9522 Rimtuzalcap

CAD-1883

Potassium Channel Membrane transporter/Ion channel
Rimtuzalcap (CAD-1883) 是首创的,选择性的小电导钙激活钾通道 (SK 通道) 正变构调节剂。Rimtuzalcap 可用于运动障碍的研究,包括脊髓小脑性共济失调 (SCA)和特发性震颤 (ET)。
T70282 Drofenine

Drofenin is an anticonvulsant. It is an anticholinergic that acts both at the level of the nerves and the muscle fibers (neurotropic musculotropic effect). Drofenin also acts as FIASMA (functional inhibitor of acid sphingomyelinase )
T70616 ACT-672125

ACT-672125 is a Potent CXCR3 Antagonist with Therapeutic Potential in Autoimmune Diseases. ACT-672125 showed good physicochemical properties and safety profile. In a proof-of-mechanism model of lung inflammation, ACT-672125 inhibited the recruitment of CXCR3 expressing T cells into the inflamed lung in a dose-dependent manner.
T68587 Oxmetidine mesylate

Oxmetidine mesylate is an antagonist to Histamine H2 Receptors
T12927 SK1-IN-1

S1P Receptor GPCR/G Protein
SK1-IN-1 is a potent inhibitor of sphingosine kinase 1 (SPHK1)(IC50 of 58 nM).
T60798 SK1- I hydrochloride

SK1-I hydrochloride (BML-258 hydrochloride) 是鞘氨醇类似物,能够增强细胞自噬并显示抗癌活性。SK1-I hydrochloride 是同工酶特异性SPHK1竞争抑制剂 (Ki = 10 μM)。
T70252 RU1968 bis-TFA salt

RU1968 bis-TFA salt is an inhibitor of the sperm-specific Ca2+ channel CatSper, thereby inhibiting human Slo3 with about 15-fold lower potency than CatSper.
T61605 SK3 Channel-IN-1

SK3 Channel-IN-1 (compound 7a) is a powerful and selective modulator of the SK3 channel. It demonstrates significant efficacy in inhibiting breast cancer MDA-MB-435 cell migration while maintaining low cytotoxicity in other cell lines. Furthermore, SK3 Channel-IN-1 exhibits the ability to modulate ion channel activity in cancer cells [1].
T30485 SK1-I

BML 258,BML-258,BML258,BML-258 HCl

BML-258 HCl was removed and discontinued.
T0143 Bisoprolol hemifumarate

富马酸比索洛尔,(±)-Bisoprolol hemifumarate,Bisoprolol fumarate,Bisoprolol hemifumarate salt,EMD33512,(±)-Bisoprolol (hemifumarate)

Adrenergic Receptor GPCR/G Protein; Neuroscience
Bisoprolol hemifumarate 是一种 β1 肾上腺素受体阻断剂。
T8461 SKI V

Apoptosis; PI3K; S1P Receptor Apoptosis; GPCR/G Protein; PI3K/Akt/mTOR signaling
SKI V 是一种非竞争性非脂质鞘氨醇激酶抑制剂,对 GST-hSK 的IC50为 2 μM。 它减少有丝分裂的第二信使鞘氨醇-1-磷酸的形成,可诱导细胞凋亡并具有抗肿瘤活性。它还抑制PI3K,对 hPI3k 的IC50为 6 μM。

化合物

SK-575
Cat.No: T69596
Synonym:
Target:
SK609 HCl
Cat.No: T24797
Synonym: SK-609 HCl,SK609 hydrochloride,SK 609 HCl,SK 609 hydrochloride,SK-609 hydrochloride
Target:
SK&F 107461
Cat.No: T34650
Synonym: SK&F107461,SK&F-107461
Target:
SK33
Cat.No: T12928
Synonym:
Target: Androgen Receptor
SK-7041
Cat.No: T24798
Synonym: SK 7041
Target:
SK&F 104976
Cat.No: T26191
Synonym: SK&F104976,Skf104976,Skf 104976,SK&F-104976,Skf-104976
Target:
Metiamide
Cat.No: T7524
Synonym: 甲硫米特,SK&F 92058
Target: Histamine Receptor
Upacicalcet
Cat.No: T29067
Synonym: PLS-240,SK-1403,AJT-240
Target: Calcium Channel
Apomine
Cat.No: T26644
Synonym: SK&F-99085,APB-231-A2,APB-231-A-2,SR-9223i,SK&F-99085,SR-45023A
Target: HMG-CoA Reductase
Anagliptin
Cat.No: T7133
Synonym: SK-0403,阿拉格列汀
Target: Proteasome, DPP-4
SK&F 108361
Cat.No: T34651
Synonym: Skf-108361,SK&F-108361,Skf 108361,SK&F108361,Skf108361
Target:
Propagermanium
Cat.No: T20641
Synonym: Dipropanoic acid germanium sequioxide,SK-818,Ge 132,二羧乙基三氧化二锗,Ge132,SK 818,Ge-132
Target: Others
SK&F 39728-A
Cat.No: T34652
Synonym: SK&F39728-A,SK&F 1-39728,SK&F-39728-A,Skf 39728-A
Target:
SK&F 103784
Cat.No: T24795
Synonym: Skf 103784,Skf-103784,Skf103784
Target:
Mirodenafil dihydrochloride
Cat.No: TQ0126
Synonym: SK-3530 dihydrochloride,米罗那非二盐酸盐
Target: PDE
SK&F-95601
Cat.No: T28787
Synonym: SK&F 95601,SKF95601,SKF 95601,SKF-95601
Target:
SK&F 106760
Cat.No: T26190
Synonym: SK&,F-106760,SKF 106760,SKF-106760,F106760,SKF106760,F 106760
Target:
Phen Green SK diacetate
Cat.No: T41273
Synonym:
Target:
SK-216
Cat.No: T28788
Synonym: SK216.Plasminogen activator inhibitor-1 (PAI-1) inhibitor
Target:
SK&F 107260
Cat.No: T24796
Synonym: Skf107260,Skf-107260,Skf 107260
Target:
Atiprimod dimaleate
Cat.No: T23761
Synonym: SK&F-106615,SK&F 106615,SK&F106615
Target:
SK609
Cat.No: T70618
Synonym:
Target:
Xylonidine
Cat.No: T35203
Synonym: SK&F-35866,SK&F35866,SK&F 35866
Target:
SKI2852
Cat.No: T28796
Synonym: SK I2852,SKI-2852
Target:
SK 946
Cat.No: T70283
Synonym:
Target:
NSC 157449
Cat.No: T33740
Synonym: SK&F-83589,SK&F 83589,NSC157449,NSC-157449
Target:
Chlorasquin
Cat.No: T23883
Synonym: Ccnsc-529,861,Ccnsc 529,861,SK 29861,Ccnsc529,861,SK-29861
Target:
SK-575-NEG
Cat.No: T74558
Synonym:
Target:
SK-MLCK M13
Cat.No: T81151
Synonym:
Target:
Mirodenafil
Cat.No: T16079
Synonym: 米罗那非,SK3530
Target: PDE
Glaspimod
Cat.No: T25453
Synonym: F 107647,SK&,F-107647,F107647
Target:
Olaflur
Cat.No: T33787
Synonym: SKF 38095,GA 297,SK&F 38095
Target:
Dehydelone
Cat.No: T31364
Synonym: KOS1584,SK-10088,KOS-1584,R-1645,SK10088,R1645
Target:
Lobendazole
Cat.No: T32834
Synonym: SK&F 24529,SKF 24529,NSC-42044,NSC42044,NSC 42044
Target:
SKF-97574 HCl
Cat.No: T28794
Synonym: SKF97574,SKF-97574,B-9937-051,BY 574,SKF 97574,SK&F-97574
Target:
Icotidine
Cat.No: T68818
Synonym:
Target:
SK1071
Cat.No: T34653
Synonym:
Target:
BTYNB
Cat.No: T9033
Synonym: MDK6620,BTYNB IMP1 Inhibitor
Target: Others, c-Myc, NF-κB
PBT434 HBr
Cat.No: T71174
Synonym:
Target:
Rimtuzalcap
Cat.No: T9522
Synonym: CAD-1883
Target: Potassium Channel
Drofenine
Cat.No: T70282
Synonym:
Target:
ACT-672125
Cat.No: T70616
Synonym:
Target:
Oxmetidine mesylate
Cat.No: T68587
Synonym:
Target:
SK1-IN-1
Cat.No: T12927
Synonym:
Target: S1P Receptor
SK1- I hydrochloride
Cat.No: T60798
Synonym:
Target:
RU1968 bis-TFA salt
Cat.No: T70252
Synonym:
Target:
SK3 Channel-IN-1
Cat.No: T61605
Synonym:
Target:
SK1-I
Cat.No: T30485
Synonym: BML 258,BML-258,BML258,BML-258 HCl
Target:
Bisoprolol hemifumarate
Cat.No: T0143
Synonym: 富马酸比索洛尔,(±)-Bisoprolol hemifumarate,Bisoprolol fumarate,Bisoprolol hemifumarate salt,EMD33512,(±)-Bisoprolol (hemifumarate)
Target: Adrenergic Receptor
SKI V
Cat.No: T8461
Synonym:
Target: Apoptosis, PI3K, S1P Receptor
Cat. No. Product Name Target Signaling Pathways
T2218 8-Azaguanine

Azaguanine-8,SK 1150,8-氮鸟嘌呤,NSC-749,SF-337

Nucleoside Antimetabolite/Analog; Others; Endogenous Metabolite Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
8-Azaguanine (SK 1150) 是一种具有潜在抗肿瘤活性的嘌呤类似物。它易于掺入核糖核酸中,干扰正常的生物合成途径,从而抑制细胞生长,可作为抗代谢药。
T75634 Demycarosyl-3D-β-D-digitoxosylmithramycin SK

Demycarosyl-3D-β-D-digitoxosylmithramycin SK 为Mithramycin类似物,展现出显著的抗肿瘤活性。该化合物通过与DNA结合蛋白结合并抑制其功能,有效阻断肿瘤细胞的增殖与生长。
TN1520 Isoforskolin

Coleonol B

IL Receptor; TNF Apoptosis; Immunology/Inflammation
Isoforskolin 源自毛喉鞘蕊花,可减少人单核白细胞中 TNF-α、IL-1β、IL-6 和 IL-8 的分泌。Isoforskolin 可用于治疗莱姆关节炎的研究。
TN1040 Skullcapflavone II

COX; Antibacterial; TGF-beta/Smad Immunology/Inflammation; Microbiology/Virology; Neuroscience; Stem Cells
Skullcapflavone II 是从黄芩中提取的黄酮,具有抗炎作用。它对 M. aurum 和 M. bovisBCG 具有较强的抗菌活性。它还调节破骨细胞的分化、存活和功能。
T3869 Skimmin

茵芋苷,Skimmine

Others Others
Skimmin (Skimmine) 是一种香豆素类物质。存在于圆锥绣球中,能够抑制免疫复合物的沉积,具有抗炎作用。
T2939 Forskolin

毛喉素,Coleonol,Colforsin

FXR; Adenylyl cyclase; AChR; Autophagy Autophagy; Metabolism; Neuroscience
Forskolin (Coleonol) 属于天然产物,是一种腺苷酸环化酶激活剂 (EC50=0.5 μM)。Forskolin 可以增加 cAMP 水平,可以激活 PXR 和 FXR,也可以诱导细胞自噬。Forskolin 对心脏产生正性肌力作用,具有血小板抗凝集和降压作用。
T2S2109 Skimmianine

beta-Fagarine,Skimmianin,茵芋碱,Chloroxylonine,Skimmiamine

Others Others
Skimmianine (Chloroxylonine) 是一种呋喹啉类生物碱,主要存在于芸香科,具有抗炎、抗痉挛和抗血小板聚集活性。它对多种癌细胞系具有细胞毒性和基因毒性。
T5654 Musk ketone

Others Others
Musk ketone 可诱导癌细胞生长抑制和凋亡。它增加谷胱甘肽 S-转移酶的活性,因此可能被证明是有用的癌症化学保护剂。
T5281 Skatole

粪臭素,Scatole,3-Methylindole,3-​Methylindole,3-甲基吲哚,3-Methyl-1H-indole,beta-Methylindole

AhR; p38 MAPK; Aryl Hydrocarbon Receptor; Endogenous Metabolite; Antibacterial; Autophagy; Antifungal Autophagy; Immunology/Inflammation; MAPK; Metabolism; Microbiology/Virology
Skatole (3-Methyl-1H-indole) 是由肠道菌群产生的,通过激活芳基烃受体和 p38调节肠上皮细胞功能。
TN2112 Przewalskinic acid A

Others Others
Przewalskinic acid A is a rare, water-soluble, and highly biologically active ingredient found, thus far, only in the Salvia przewalskii Maxim herb.
TN4827 Preskimmianine

Others Others
Preskimmianine is the biogenetic precursor of skimmianine.It can significantly inhibit nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 cells.
TN6197 8,8''-Biskoenigine

8,8''-Biskoenigine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6197,CAS号为 477890-82-7。
TN4835 Przewalskin

HIV Protease Microbiology/Virology; Proteases/Proteasome
Przewalskin A and Przewalskin B showed modest anti-HIV-1 activity with EC50 = 41 and 30 microg/mL, respectively.
TN1001 Apiosylskimmin

Others Others
Apiosylskimmin is a natural product from Angelica gigas.
T16160 Musk tibetene

Musk tibetine

Others Others
Musk tibetine reveals no genotoxicity in the micronucleus test with human lymphocytes and human hepatoma cell lines. Musk tibetene is a nitro musk compound with carcinogenic activity.
T75545 PCSK9-IN-9

PCSK9-IN-9 是一种天然来源的异香豆素。PCSK9-IN-9 可抑制原蛋白转化酶枯草菌素 kexin 型 9 (PCSK9)、IDOL 和 SREBP2的 mRNA 表达水平。PCSK9-IN-9 抑制 PCSK9的 IC50为 11.9 μM。
TN4073 Forskolin G

Others Others
Forskolin is known to elevate intracellular cAMP levels.
TN5019 Siegeskaurolic acid

TNF; NOS; NF-κB; COX; NO Synthase; Prostaglandin Receptor Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuroscience; NF-κB
Siegeskaurolic acid 是一种具有抗炎活性的天然产物。
TN4074 Forskolin J

Others Others
Forskolin J 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4074,CAS号为 81873-08-7。
TN5033 Skullcapflavone I

IL Receptor; Caspase; Prostaglandin Receptor Apoptosis; GPCR/G Protein; Immunology/Inflammation; Proteases/Proteasome
Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dependent manner. Skullcapflavone I se
T3S1589 Notoginsenoside Fa

Others Others
Notoginsenoside Fa 是一种原人参二醇型皂苷,从P. notoginseng 提取出来得到,有激活和恢复退化脑功能的潜能。
TN1516 Cnidicin

蛇床素,4,9-双[(3-甲基-2-丁烯-1-基)氧基]-7H-呋喃并[3,2-G][1]苯并吡喃-7-酮

NOS; NO Synthase Immunology/Inflammation
Cnidicin 是一种香豆素,对肥大细胞脱颗粒及 RAW 264.7 细胞产生一氧化氮具有抑制作用。
TN2256 Taccalonolide B

根薯酮内酯B,根薯酮内酯 B

Microtubule Associated Cytoskeletal Signaling
Taccalonolide B 是从广西裂果薯中分离得到的一种微管稳定剂,具有抗肿瘤活性。它抑制 SK-OV-3 细胞的生长,IC50 为 208 nM,在体外对过表达 P-糖蛋白 (Pgp) 和多药耐药蛋白 (MRP7) 的细胞系有效。
TN2097 Pomolic acid

坡模酸

Apoptosis; Caspase; HIV Protease; AMPK Apoptosis; Chromatin/Epigenetic; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Pomolic acid 是从野鸦椿中分离出来的一种五环三萜烯。它抑制肿瘤细胞的生长,诱导细胞凋亡,有用于前列腺癌的潜力。
TN2254 Taccalonolide A

根薯酮内酯A,根薯酮内酯 A

Apoptosis; Microtubule Associated Apoptosis; Cytoskeletal Signaling
Taccalonolide A 是从水田七根茎中分离得到的一种类固醇,具有细胞毒性和抗疟活性。它在体外对过表达 p 糖蛋白、多药耐药蛋白 7 细胞系有抑制作用,抑制 SK-OV-3 细胞生长的 IC50值为 622 nM。它是微管稳定剂,能引起 G2-M 期滞留、Bcl-2 磷酸化,并引发细胞凋亡。
T2850 Bicuculline

荷包牡丹碱,(+)-Bicuculline,d-Bicuculline

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Bicuculline ((+)-Bicuculline) 是从东北延胡索中提取的一种生物碱,能阻断 Ca2+激活钾 (SK) 通道。它是一种竞争性的神经递质 GABAA 受体拮抗剂,IC50为 2 μM。
T6S1487 Ginsenoside Rg5

人参皂苷Rg5,人参皂甙 Rg5

NF-κB; COX; IGF-1R Immunology/Inflammation; Neuroscience; NF-κB; Tyrosine Kinase/Adaptors
Ginsenoside Rg5 是红参的主要成分,可阻断IGF-1与其受体的结合,IC50约为90 nM。它还通过抑制NF-κB p65的 DNA 结合活性来抑制COX-2的 mRNA 表达。它可促进血管生成和改善高血压,具有抗炎和治疗阿尔茨海默病的潜力。
T3932 Viscidulin I

Others Others
Viscidulin I 存在于黄芩中,是一种天然产物。
TN2666 1alpha-Hydroxytorilin

Others Others
1alpha-Hydroxytorilin exhibits cytotoxicity against human A549, SK-OV-3, SK-MEL-2, and HCT15 tumor cells.
TN4959 Schizandriside

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Schizandriside may have anti-inflammatory effects, it has inhibitory activities against nitric oxide and prostaglandin E(2) production in IFN-γ- and lipopolysaccharide-stimulated RAW 264.7 cells. It shows significant cytotoxicity against A549, SK-OV-3, SK
TN4373 Kaempferol tetraacetate

Antifection Microbiology/Virology
Kaempferol tetraacetate is a potent antiplatelet agent. It exhibits significant cytotoxicity in vitro against three human cell lines HL-60, U937 and SK-MEL-1.
TN3832 Deoxyflindissone

Others Others
Deoxyflindissone exhibits significant cytotoxic activity against the A549, SK-OV-3, SK-MEL-2, and XF498 cell lines.
TN2669 1beta-Hydroxytorilin

Others Others
1beta-Hydroxytorilin exhibits cytotoxicity against human A549, SK-OV-3, SK-MEL-2, and HCT15 tumor cells.
TN4146 Glutinol acetate

TNF Apoptosis
Glutinol acetate shows significant cytotoxic activity against four human cancer cell lines (HL-60, SK-OV-3, A549, and HT-29), with GI(50) in the range of 11.1-17.9microM; it also has anti-inflammatory effect, exhibits moderate inhibitory activity of TNF-alpha secretion in the lipopolysaccharide (LPS)-stimulated murine RAW264.7 macrophage cell line.
TN3007 4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan

Others Others
4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan shows cytotoxic activities against four tumor cell lines (A549, SK-OV-3, SKMEL-2 and HCT15).
T82298 Glucozaluzanin C

Glucozaluzanin C,一种木脂素类化合物,由菊科鸢尾根的MeOH提取物中分离得到,显示出对多种细胞系具有显著的生物活性。具体而言,其在A549、SK-OV-3、SK-MEL-2、XF498和HCT15细胞上的ED50值依次为2.45 μg/mL、1.37 μg/mL、0.40 μg/mL、1.41 μg/mL、1.43 μg/mL。
TN6014 Norcepharadione B

鱼腥草

Norcepharadione B shows good inhibitory activity against the replication of HSV-1, it also shows antimalarial activity with EC50 values of 7.5mug/ml. Norcepharadione B exhibits significant cytotoxicity against five human tumor cell lines (A-549, SK-OV-3,
TN3862 Dihydroprehelminthosporol

Others Others
Dihydroprehelminthosporol is a strongly phytotoxic metabolite, it exhibits cytotoxicity towards two human cancer cell lines, A549 and SK-OA-3.
T37543 Anhydroepiophiobolin A

Anhydroepiophiobolin A is a sesterterpenoid fungal metabolite that has been found in B. oryzae. It is cytotoxic to HepG2 and K562 cells (IC50s = 47.1 and 35.6 μM, respectively) as well as A549, SKOV3, SK-MEL-2, XF498, and HCT15 cells (IC50s = 1.6-1.9 μg/ml). Anhydroepiophiobolin A is phytotoxic to S. viridis and D. erucoides in a leaf puncture assay.
T83597 (+)-Menthyl acetate

(+)-Menthyl acetate是一种从Cunila angustifolia Benth精油中分离得到的化学化合物。它对MCF-7细胞株具有较高的选择性,其半抑制浓度(IC50)为34.0 μg/mL,而对SK-Mel-28细胞株的选择性较低,IC50为279.9 μg/mL,并且对A549细胞没有致死作用。
T35483 19,20-Epoxycytochalasin D

19,20-Epoxycytochalasin D is a fungal metabolite that has been found in the endophytic fungus Nemania sp. UM10M. It is active against the chloroquine-sensitive and -resistant strains of P. falciparum (MIC = 0.4 ng/ml for both) without inducing cytotoxicity in Vero cells. It is cytotoxic to BT-549, LLC-PK11, and P388 cells (IC50s = 7.84, 8.4, and 0.16 &#181M, respectively) but not SK-MEL, KB, or SKOV3 cells up to a concentration of 10 &#181M.
TN2977 3-O-trans-p-Coumaroyltormentic acid

Caspase; Antifection Apoptosis; Microbiology/Virology; Proteases/Proteasome
3-O-(E)-p-coumaroyl tormentic acid may be promising lead compound for developing an effective drug for treatment of leukemia, it induces apoptotic cell death in human leukemia (HL60) via mainly mitochondrial pathway by, at least in part, Topo I inhibition. 3-O-trans-p-coumaroyltormentic acid shows cytotoxicity against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15) in vitro, the IC50 values of 13.72, 14.29,14.61, 14.04 uM, respectively. 3beta-O-cis-p-Coumaroyltormentic acid, an...
T37452 Stephacidin B

Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, including testosterone-independent PC3 and -sensitive LNCaP prostate cancer cells (IC50s = 0.37 and 0.06 μM, respectively) and estradiol-independent SK-BR-3 and -sensitive MCF-7 breast cancer cells (IC50s = 0.32 and 0.27 μM, respectively).1It induces apoptosis in HepG2 and Huh7 hepatoc...
T36749 Herboxidiene

Herboxidiene is a polyketide originally isolated from S. chromofuscus that has diverse biological activities.[1],[2,][3],[4],[5] It inhibits growth of HeLa S3, SK-MEL-2, PC3, A549, and EBC-1 cells with GI50 values ranging from 7.4 to 62 nM.3 Herboxidiene is cytostatic against human umbilical vein endothelial cells (HUVECs; (IC50 = 26 nM)) and inhibits VEGF-induced invasion and tube formation of serum-starved HUVECs in a concentration-dependent manner, indicating antiangiogenic activity.[4] Herbo...
T36954 Nemorosone

Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma cells (IC50s = 3.1-6.3 μM), including several drug-resistant clones, but not MRC-5 human embryonic fibroblasts (IC50 = >40 μM).2 It increases DNA fragmentation in LAN-1 cells in a dose-dependent manner, and decreases N-Myc protein levels and phosphorylation of ERK1/2 by MEK1/2. Nem...

天然产物

8-Azaguanine
Cat.No: T2218
Synonym: Azaguanine-8,SK 1150,8-氮鸟嘌呤,NSC-749,SF-337
Target: Nucleoside Antimetabolite/Analog, Others, Endogenous Metabolite
Demycarosyl-3D-β-D-digitoxosylmithramycin SK
Cat.No: T75634
Synonym:
Target:
Isoforskolin
Cat.No: TN1520
Synonym: Coleonol B
Target: IL Receptor, TNF
Skullcapflavone II
Cat.No: TN1040
Synonym:
Target: COX, Antibacterial, TGF-beta/Smad
Skimmin
Cat.No: T3869
Synonym: 茵芋苷,Skimmine
Target: Others
Forskolin
Cat.No: T2939
Synonym: 毛喉素,Coleonol,Colforsin
Target: FXR, Adenylyl cyclase, AChR, Autophagy
Skimmianine
Cat.No: T2S2109
Synonym: beta-Fagarine,Skimmianin,茵芋碱,Chloroxylonine,Skimmiamine
Target: Others
Musk ketone
Cat.No: T5654
Synonym:
Target: Others
Skatole
Cat.No: T5281
Synonym: 粪臭素,Scatole,3-Methylindole,3-​Methylindole,3-甲基吲哚,3-Methyl-1H-indole,beta-Methylindole
Target: AhR, p38 MAPK, Aryl Hydrocarbon Receptor, Endogenous Metabolite, Antibacterial, Autophagy, Antifungal
Przewalskinic acid A
Cat.No: TN2112
Synonym:
Target: Others
Preskimmianine
Cat.No: TN4827
Synonym:
Target: Others
8,8''-Biskoenigine
Cat.No: TN6197
Synonym:
Target:
Przewalskin
Cat.No: TN4835
Synonym:
Target: HIV Protease
Apiosylskimmin
Cat.No: TN1001
Synonym:
Target: Others
Musk tibetene
Cat.No: T16160
Synonym: Musk tibetine
Target: Others
PCSK9-IN-9
Cat.No: T75545
Synonym:
Target:
Forskolin G
Cat.No: TN4073
Synonym:
Target: Others
Siegeskaurolic acid
Cat.No: TN5019
Synonym:
Target: TNF, NOS, NF-κB, COX, NO Synthase, Prostaglandin Receptor
Forskolin J
Cat.No: TN4074
Synonym:
Target: Others
Skullcapflavone I
Cat.No: TN5033
Synonym:
Target: IL Receptor, Caspase, Prostaglandin Receptor
Notoginsenoside Fa
Cat.No: T3S1589
Synonym:
Target: Others
Cnidicin
Cat.No: TN1516
Synonym: 蛇床素,4,9-双[(3-甲基-2-丁烯-1-基)氧基]-7H-呋喃并[3,2-G][1]苯并吡喃-7-酮
Target: NOS, NO Synthase
Taccalonolide B
Cat.No: TN2256
Synonym: 根薯酮内酯B,根薯酮内酯 B
Target: Microtubule Associated
Pomolic acid
Cat.No: TN2097
Synonym: 坡模酸
Target: Apoptosis, Caspase, HIV Protease, AMPK
Taccalonolide A
Cat.No: TN2254
Synonym: 根薯酮内酯A,根薯酮内酯 A
Target: Apoptosis, Microtubule Associated
Bicuculline
Cat.No: T2850
Synonym: 荷包牡丹碱,(+)-Bicuculline,d-Bicuculline
Target: GABA Receptor
Ginsenoside Rg5
Cat.No: T6S1487
Synonym: 人参皂苷Rg5,人参皂甙 Rg5
Target: NF-κB, COX, IGF-1R
Viscidulin I
Cat.No: T3932
Synonym:
Target: Others
1alpha-Hydroxytorilin
Cat.No: TN2666
Synonym:
Target: Others
Schizandriside
Cat.No: TN4959
Synonym:
Target: Prostaglandin Receptor
Kaempferol tetraacetate
Cat.No: TN4373
Synonym:
Target: Antifection
Deoxyflindissone
Cat.No: TN3832
Synonym:
Target: Others
1beta-Hydroxytorilin
Cat.No: TN2669
Synonym:
Target: Others
Glutinol acetate
Cat.No: TN4146
Synonym:
Target: TNF
4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan
Cat.No: TN3007
Synonym:
Target: Others
Glucozaluzanin C
Cat.No: T82298
Synonym:
Target:
Norcepharadione B
Cat.No: TN6014
Synonym: 鱼腥草
Target:
Dihydroprehelminthosporol
Cat.No: TN3862
Synonym:
Target: Others
Anhydroepiophiobolin A
Cat.No: T37543
Synonym:
Target:
(+)-Menthyl acetate
Cat.No: T83597
Synonym:
Target:
19,20-Epoxycytochalasin D
Cat.No: T35483
Synonym:
Target:
3-O-trans-p-Coumaroyltormentic acid
Cat.No: TN2977
Synonym:
Target: Caspase, Antifection
Stephacidin B
Cat.No: T37452
Synonym:
Target:
Herboxidiene
Cat.No: T36749
Synonym:
Target:
Nemorosone
Cat.No: T36954
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-00775 DKK1 Protein, Human, Recombinant (His)

dickkopf WNT signaling pathway inhibitor 1,SK,DKK-1

Human HEK293 Cells
DKK1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.22 kDa and the accession number is I1W660.
TMPY-05579 PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated

PRR1,ED4,PVRR,nectin-1,OFC7,SK-12,CD111,CLPED1,HVEC...

Human HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1.
TMPK-00155 DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi)

hDkk-1,Dickkopf-1,Dkk1,hDkk1,SK,Dkk-1,Dickkopf-rela...

Human HEK293 Cells
Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 38.69 kDa and the accession number is O94907.
TMPY-05479 DKK1 Protein, Human, Recombinant (hFc)

dickkopf WNT signaling pathway inhibitor 1,DKK-1,SK

Human HEK293 Cells
DKK1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.5 kDa and the accession number is I1W660.
TMPK-00157 DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated

hDkk-1,SK,Dkk1,Dickkopf-related 1,Dickkopf-1,Dkk-1,...

Human HEK293 Cells
Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 38.69 kDa and the accession number is O94907.
TMPK-00156 DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi)

Dickkopf-1,Dkk1,hDkk-1,hDkk1,Dkk-1,SK,Dickkopf-rela...

Human HEK293 Cells
Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 40.25 kDa and the accession number is O94907.
TMPK-00158 DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated

hDkk1,Dkk1,Dickkopf-1,Dkk-1,Dickkopf-related 1,SK,h...

Human HEK293 Cells
Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 40.25 kDa and the accession number is O94907.
TMPK-00313 Nectin-1 Protein, Human, Recombinant (His & Avi), Biotinylated

HIgRPVRR,OFC7,CLPED1,SK-12,MGC142031,HIgR,PVRL1,HVE...

Human HEK293 Cells
Nectin-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 36.9 kDa and the accession number is Q15223-1.
TMPK-00312 Nectin-1 Protein, Human, Recombinant (His & Avi)

PVRR1,HIgRPVRR,PVRL1,CLPED1,MGC142031,SK-12,HVEC,PR...

Human HEK293 Cells
Nectin-1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 36.9 kDa and the accession number is Q15223.
TMPY-01572 PVRL1/NECTIN1 Protein, Human, Recombinant (His)

HVEC,ED4,PRR1,PVRR1,nectin-1,HIgR,poliovirus receptor-relate...

Human HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.4 kDa and the accession number is Q15223-1.
TMPY-01571 PVRL1/NECTIN1 Protein, Human, Recombinant (hFc)

HV1S,ED4,poliovirus receptor-related 1 (herpesvirus entry me...

Human HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1.
TMPY-00162 Influenza A H7N3 (A/chicken/SK/HR-00011/2007) Hemagglutinin/HA1 Protein (His)

Harvey rat sarcoma viral oncogene homolog

H7N3 HEK293 Cells
Influenza A H7N3 (A/chicken/SK/HR-00011/2007) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.7 kDa and the accession number is B6CU21.
TMPY-00408 PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His)

FH3,proprotein convertase subtilisin/kexin type 9,LDLCQ1,HCH...

Human HEK293 Cells
PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.6 kDa and the accession number is AAV67948.1.
TMPY-04966 PCSK9 Protein, Human, Recombinant (D374Y, His)

LDLCQ1,NARC-1,PC9,NARC1,HCHOLA3,proprotein convertase subtil...

Human HEK293 Cells
PCSK9 Protein, Human, Recombinant (D374Y, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.5 kDa and the accession number is Q8NBP7-1.
TMPY-05131 PCSK9 Protein, Human, Recombinant (His & Avi), Biotinylated

NARC-1,PC9,LDLCQ1,NARC1,FH3,proprotein convertase subtilisin...

Human HEK293 Cells
PCSK9 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 74.3 kDa and the accession number is Q8NBP7-1.
TMPY-04356 GSK3B Protein, Human, Recombinant (His)

glycogen synthase kinase 3 beta,glycogen synthase kinase 3 β

Human Baculovirus Insect Cells
GSK3B Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is P49841-2.
TMPK-00687 keratin, type I cytoskeletal 19 (310-399) Protein, Canine, Recombinant (His)

KRT19,CK-19,K19,Keratin-19,CK19,Keratin19,Cytokeratin19,Cyto...

Canine E. coli
Keratin 19 (K19) belongs to the keratin family of proteins, which maintains structural integrity of epithelia. In cancer, K19 is highly expressed in several types where it serves as a diagnostic marker.
TMPY-04563 CASK Protein, Human, Recombinant (His & GST)

calcium/calmodulin-dependent serine protein kinase (MAGUK fa...

Human Baculovirus Insect Cells
CASK Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 130 kDa and the accession number is O14936-4.
TMPY-05114 PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His), Biotinylated

LDLCQ1,NARC-1,PC9,FH3,NARC1,HCHOLA3,proprotein convertase su...

Human HEK293 Cells
PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.6 kDa and the accession number is Q8NBP7-1.
TMPH-00471 PSK-alpha Protein, Daucus carota, Recombinant (His & KSI)

Daucus carota E. coli
PSK-alpha Protein, Daucus carota, Recombinant (His & KSI) is expressed in E. coli.
TMPY-04383 CSK Protein, Human, Recombinant (GST)

c-src tyrosine kinase

Human Baculovirus Insect Cells
CSK Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 77 kDa and the accession number is P41240.
TMPY-04414 MUSK Protein, Human, Recombinant (aa 433-783, His & GST)

FADS,CMS9,muscle, skeletal, receptor tyrosine kinas...

Human Baculovirus Insect Cells
Muscle, skeletal receptor tyrosine-protein kinase, also known as Muscle-specific tyrosine-protein kinase receptor, Muscle-specific kinase receptor, and MUSK, is a single-pass type I membrane protein that belongs to the protein kinase superfamily and tyr protein kinase family. MUSK contains one FZ (frizzled) domain, three Ig-like C2-type (immunoglobulin-like) domains, and one protein kinase domain. This protein is a muscle-specific tyrosine kinase receptor and it may play a role in clustering of ...
TMPH-02790 MUSK Protein, Mouse, Recombinant (His & Myc & SUMO)

Mouse E. coli
MUSK Protein, Mouse, Recombinant (His & Myc & SUMO) is expressed in E. coli.
TMPY-05199 PCSK9 Protein, Human, Recombinant (D374Y, mFc)

PC9,proprotein convertase subtilisin/kexin type 9,FH3,NARC1,...

Human HEK293 Cells
PCSK9 Protein, Human, Recombinant (D374Y, mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 97.5 kDa and the accession number is Q8NBP7-1.
TMPK-00483 PCSK9 Protein, Cynomolgus, Recombinant (His)

PCSK9

Cynomolgus HEK293 Cells
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1.The first two PCSK9 inhibitors, alirocumab and evolocumab, were approved as once every two week injections, by the U.S. Food and Drug Administration in 2015 for lowering LDL-particle concentrations when statins and other drugs were not sufficiently effective or poorly tolerated.
TMPY-05906 Influenza A H1N1 (A/swine/Saskatchewan/SD0056/2014) Hemagglutinin/HA Protein (His)

Harvey rat sarcoma viral oncogene homolog

H1N1 HEK293 Cells
Influenza A H1N1 (A/swine/Saskatchewan/SD0056/2014) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is A0A0U4T2C2.
TMPY-05218 PCSK9 Protein, Human, Recombinant (mFc)

HCHOLA3,PC9,proprotein convertase subtilisin/kexin type 9,FH...

Human HEK293 Cells
PCSK9 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 97.4 kDa and the accession number is Q8NBP7-1.
TMPJ-00369 PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated

Subtilisin/Kexin-Like Protease PC9,PCSK9,NARC1,Prop...

Human HEK293 Cells
PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-8xHis-HA-Avi tag. The predicted molecular weight is 18 and 58-70 and 90-150 KDa and the accession number is Q8NBP7.
TMPY-04439 GSK3B Protein, Mouse, Recombinant (His)

GSK-3,7330414F15Rik,C86142,glycogen synthase kinase...

Mouse Baculovirus Insect Cells
GSK3B Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49 kDa and the accession number is Q9WV60.
TMPY-06712 Tssk3 Protein, Mouse, Recombinant (GST)

Stk22d,Stk22c

Mouse Baculovirus Insect Cells
Tssk3 Protein, Mouse, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 56.37 kDa and the accession number is NP_536690.1.
TMPY-00995 PCSK9 Protein, Rhesus, Recombinant (His)

proprotein convertase subtilisin/kexin type 9

Rhesus HEK293 Cells
PCSK9 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.7 kDa and the accession number is A8T666.
TMPY-05217 PCSK9 Protein, Mouse, Recombinant (mFc)

HCHOLA3,Narc1,AI415265,AI747682,FH3,proprotein convertase su...

Mouse HEK293 Cells
PCSK9 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 97.6 kDa and the accession number is Q80W65.
TMPH-03422 Rotavirus A (strain Nebraska calf diarrhea virus) VP7 Protein (His & Myc)

RV-A E. coli
Rotavirus A (strain Nebraska calf diarrhea virus) VP7 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 36.2 kDa and the accession number is P04511.
TMPY-04392 RSK3 Protein, Human, Recombinant (GST)

HU-2,ribosomal protein S6 kinase, 90kDa, polypeptide 2,S6K-α...

Human Baculovirus Insect Cells
Ribosomal protein S6 kinase alpha-2, also known as 9 kDa ribosomal protein S6 kinase 2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, Ribosomal S6 kinase 3, RSK-3, RPS6KA2 and MAPKAPK1C, is a nucleus protein that belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family and S6 kinase subfamily. RPS6KA2 / RSK-3 is expressed in many tissues. Highest expression is in lung and skeletal muscle. The expression of RPS6KA2 reduced proliferation, caused G1 a...
TMPY-04754 CASK Protein, Human, Recombinant

CMG,LIN2,MRXSNA,CAMGUK,calcium/calmodulin-dependent serine p...

Human Baculovirus Insect Cells
CASK Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 102.1 kDa and the accession number is O14936-4.
TMPY-01565 PCSK9 Protein, Rat, Recombinant (His)

proprotein convertase subtilisin/kexin type 9

Rat HEK293 Cells
PCSK9 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.8 kDa and the accession number is A6JYM6.
TMPH-00470 PSKR Protein, Daucus carota, Recombinant (His)

Daucus carota P. pastoris (Yeast)
PSKR Protein, Daucus carota, Recombinant (His) is expressed in Yeast.
TMPY-01245 PCSK9 Protein, Mouse, Recombinant (His)

proprotein convertase subtilisin/kexin type 9,AI747682,Narc1...

Mouse HEK293 Cells
PCSK9 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.6 kDa and the accession number is Q80W65.
TMPH-00034 ASFV (isolate Tick/South Africa/Pretoriuskop Pr4/1996) p12 Protein (His)

Protein p12,Pret-110,Inner membrane protein p12

ASFV E. coli
Virus attachment protein. ASFV (isolate Tick/South Africa/Pretoriuskop Pr4/1996) p12 Protein (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 12.7 kDa and the accession number is P0C9Y3.
TMPH-02131 SKP2 Protein, Human, Recombinant (His & SUMO)

Human E. coli
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1, CDT1, RBL2, KMT2A/MLL1, CDK9, RAG2, FOXO1, UB...
TMPY-05270 PCSK9 Protein, Human, Recombinant (D374Y, mFc), Biotinylated

FH3,NARC-1,PC9,LDLCQ1,proprotein convertase subtilisin/kexin...

Human HEK293 Cells
PCSK9 Protein, Human, Recombinant (D374Y, mFc), Biotinylated is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 97.5 kDa and the accession number is Q8NBP7-1.
TMPJ-00368 PCSK9 Protein, Human, Recombinant (Avi), Biotinylated

Subtilisin/Kexin-Like Protease PC9,PC9,NARC-1,Proprotein Con...

Human HEK293 Cells
PCSK9 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 19&65 KDa and the accession number is Q8NBP7.
TMPK-00045 SKP1 Protein, Human, Recombinant (His, Avi), Biotinylated

SIII,OCP-2,TCEB1L,EMC19,OCP-II,OCP2,SKP1A,p19A

Human HEK293 Cells
The S-phase Kinase-Associated Protein 1 (SKP1) is a core component of the SKP1, Cullin 1, F-box protein (SCF) complex, an E3 ubiquitin ligase that serves to poly-ubiquitinate a vast array of protein targets as a signal for their proteasomal degradation, thereby playing a critical role in the regulation of downstream biological processes. SKP1 Protein, Human, Recombinant (His, Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His and C-Avi tag. The predicted molecular weight is 21....
TMPH-01405 GSK3B Protein, Human, Recombinant (E. coli, His)

Human E. coli
GSK3B Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 50.7 kDa and the accession number is P49841.
TMPY-01635 PCSK1 Protein, Human, Recombinant (His)

proprotein convertase subtilisin/kexin type 1,SPC3,PC1,BMIQ1...

Human HEK293 Cells
Neuroendocrine convertase 1, also known as Prohormone convertase 1, Proprotein convertase 1, PCSK1 and NEC1, is an enzyme which belongs to the peptidase S8 family and Furin subfamily. PCSK1 is an enzyme that performs the proteolytic cleavage of prohormones to their intermediate (or sometimes completely cleaved) forms. It is present only in neuroendocrine cells such as brain, pituitary and adrenal, and most often cleaves after a pair of basic residues within prohormones but can occasionally cleav...
TMPK-00044 SKP1 Protein, Human, Recombinant (His, Avi)

OCP-II,TCEB1L,SIII,p19A,OCP-2,EMC19,OCP2,SKP1A

Human HEK293 Cells
The S-phase Kinase-Associated Protein 1 (SKP1) is a core component of the SKP1, Cullin 1, F-box protein (SCF) complex, an E3 ubiquitin ligase that serves to poly-ubiquitinate a vast array of protein targets as a signal for their proteasomal degradation, thereby playing a critical role in the regulation of downstream biological processes. SKP1 Protein, Human, Recombinant (His, Avi) is expressed in HEK293 mammalian cells with N-His and C-Avi tag. The predicted molecular weight is 21.43 kDa and the...
TMPH-03424 Rotavirus A (strain Nebraska calf diarrhea virus) VP4 Protein (His & Myc)

RV-A E. coli
Rotavirus A (strain Nebraska calf diarrhea virus) VP4 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.2 kDa and the accession number is P17465.
TMPH-01718 MUSK Protein, Human, Recombinant (His)

Human P. pastoris (Yeast)
MUSK Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 53.8 kDa and the accession number is O15146.
TMPH-03417 Rotavirus A (strain Nebraska calf diarrhea virus) VP6 Protein (His)

RV-A E. coli
Rotavirus A (strain Nebraska calf diarrhea virus) VP6 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 50.8 kDa and the accession number is A7J3A1.
TMPY-04760 CSK Protein, Mouse, Recombinant

c-src tyrosine kinase,AW212630,p50CSK

Mouse Baculovirus Insect Cells
CSK Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 50.9 kDa and the accession number is P41241.
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重组蛋白

DKK1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00775
Species: Human
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05579
Species: Human
Expression System: HEK293 Cells
DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi)
Cat.No: TMPK-00155
Species: Human
Expression System: HEK293 Cells
DKK1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05479
Species: Human
Expression System: HEK293 Cells
DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPK-00157
Species: Human
Expression System: HEK293 Cells
DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi)
Cat.No: TMPK-00156
Species: Human
Expression System: HEK293 Cells
DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPK-00158
Species: Human
Expression System: HEK293 Cells
Nectin-1 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00313
Species: Human
Expression System: HEK293 Cells
Nectin-1 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00312
Species: Human
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01572
Species: Human
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01571
Species: Human
Expression System: HEK293 Cells
Influenza A H7N3 (A/chicken/SK/HR-00011/2007) Hemagglutinin/HA1 Protein (His)
Cat.No: TMPY-00162
Species: H7N3
Expression System: HEK293 Cells
PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His)
Cat.No: TMPY-00408
Species: Human
Expression System: HEK293 Cells
PCSK9 Protein, Human, Recombinant (D374Y, His)
Cat.No: TMPY-04966
Species: Human
Expression System: HEK293 Cells
PCSK9 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05131
Species: Human
Expression System: HEK293 Cells
GSK3B Protein, Human, Recombinant (His)
Cat.No: TMPY-04356
Species: Human
Expression System: Baculovirus Insect Cells
keratin, type I cytoskeletal 19 (310-399) Protein, Canine, Recombinant (His)
Cat.No: TMPK-00687
Species: Canine
Expression System: E. coli
CASK Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04563
Species: Human
Expression System: Baculovirus Insect Cells
PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His), Biotinylated
Cat.No: TMPY-05114
Species: Human
Expression System: HEK293 Cells
PSK-alpha Protein, Daucus carota, Recombinant (His & KSI)
Cat.No: TMPH-00471
Species: Daucus carota
Expression System: E. coli
CSK Protein, Human, Recombinant (GST)
Cat.No: TMPY-04383
Species: Human
Expression System: Baculovirus Insect Cells
MUSK Protein, Human, Recombinant (aa 433-783, His & GST)
Cat.No: TMPY-04414
Species: Human
Expression System: Baculovirus Insect Cells
MUSK Protein, Mouse, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-02790
Species: Mouse
Expression System: E. coli
PCSK9 Protein, Human, Recombinant (D374Y, mFc)
Cat.No: TMPY-05199
Species: Human
Expression System: HEK293 Cells
PCSK9 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00483
Species: Cynomolgus
Expression System: HEK293 Cells
Influenza A H1N1 (A/swine/Saskatchewan/SD0056/2014) Hemagglutinin/HA Protein (His)
Cat.No: TMPY-05906
Species: H1N1
Expression System: HEK293 Cells
PCSK9 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05218
Species: Human
Expression System: HEK293 Cells
PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated
Cat.No: TMPJ-00369
Species: Human
Expression System: HEK293 Cells
GSK3B Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04439
Species: Mouse
Expression System: Baculovirus Insect Cells
Tssk3 Protein, Mouse, Recombinant (GST)
Cat.No: TMPY-06712
Species: Mouse
Expression System: Baculovirus Insect Cells
PCSK9 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-00995
Species: Rhesus
Expression System: HEK293 Cells
PCSK9 Protein, Mouse, Recombinant (mFc)
Cat.No: TMPY-05217
Species: Mouse
Expression System: HEK293 Cells
Rotavirus A (strain Nebraska calf diarrhea virus) VP7 Protein (His & Myc)
Cat.No: TMPH-03422
Species: RV-A
Expression System: E. coli
RSK3 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04392
Species: Human
Expression System: Baculovirus Insect Cells
CASK Protein, Human, Recombinant
Cat.No: TMPY-04754
Species: Human
Expression System: Baculovirus Insect Cells
PCSK9 Protein, Rat, Recombinant (His)
Cat.No: TMPY-01565
Species: Rat
Expression System: HEK293 Cells
PSKR Protein, Daucus carota, Recombinant (His)
Cat.No: TMPH-00470
Species: Daucus carota
Expression System: P. pastoris (Yeast)
PCSK9 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01245
Species: Mouse
Expression System: HEK293 Cells
ASFV (isolate Tick/South Africa/Pretoriuskop Pr4/1996) p12 Protein (His)
Cat.No: TMPH-00034
Species: ASFV
Expression System: E. coli
SKP2 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02131
Species: Human
Expression System: E. coli
PCSK9 Protein, Human, Recombinant (D374Y, mFc), Biotinylated
Cat.No: TMPY-05270
Species: Human
Expression System: HEK293 Cells
PCSK9 Protein, Human, Recombinant (Avi), Biotinylated
Cat.No: TMPJ-00368
Species: Human
Expression System: HEK293 Cells
SKP1 Protein, Human, Recombinant (His, Avi), Biotinylated
Cat.No: TMPK-00045
Species: Human
Expression System: HEK293 Cells
GSK3B Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01405
Species: Human
Expression System: E. coli
PCSK1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01635
Species: Human
Expression System: HEK293 Cells
SKP1 Protein, Human, Recombinant (His, Avi)
Cat.No: TMPK-00044
Species: Human
Expression System: HEK293 Cells
Rotavirus A (strain Nebraska calf diarrhea virus) VP4 Protein (His & Myc)
Cat.No: TMPH-03424
Species: RV-A
Expression System: E. coli
MUSK Protein, Human, Recombinant (His)
Cat.No: TMPH-01718
Species: Human
Expression System: P. pastoris (Yeast)
Rotavirus A (strain Nebraska calf diarrhea virus) VP6 Protein (His)
Cat.No: TMPH-03417
Species: RV-A
Expression System: E. coli
CSK Protein, Mouse, Recombinant
Cat.No: TMPY-04760
Species: Mouse
Expression System: Baculovirus Insect Cells
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