146
63
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39
Cat. No. | Product Name | ||
---|---|---|---|
L7600 | 趋化因子抑制剂库 | 59 compounds | |
59 种趋化因子或其受体抑制剂的独特集合,可用于高通量筛选和高内涵筛选; | |||
L3600 | 细胞因子抑制剂库 | 604 compounds | |
604 个与细胞因子紧密相关的化合物集合,是高通量、高内涵筛选的良好载体; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T68192 | OK-1035 | ||
OK-1035 is a potent and selective DNA-PK inhibitor. When a synthetic peptide was used as a substrate, OK-1035 caused 50% inhibition of DNA-PK activity at 8 microM. OK-1035 inhibited the phosphorylation by DNA-PK of consensus peptide as well as that of recombinant human wild type-p53. Kinetic studies indicated that OK-1035 inhibited DNA-PK activity in an ATP-competitive manner. | |||
T80220 |
OK2
|
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
OK2为CCN2/EGFR交互作用的特异性抑制剂,其通过结合CCN2的CT结构域,有效阻断了CCN2/EGFR的交互作用。该化合物适用于肾纤维化与慢性肾脏疾病研究。 | |||
TP2419 |
V-9-M Cholecystokinin nonapeptide
V 9 M,Prepro CCK Fragment V-9-M,Val-pro-val-glu-ala-val-asp-pro-met,Cholecystokinin Precursor (24-32),V9M,V-9-M |
Beta Amyloid | Neuroscience |
V-9-M Cholecystokinin nonapeptide (Prepro CCK Fragment V-9-M) 是胆囊收缩素(CCK)的前体化合物。胆囊收缩素(CCK)是一种刺激胆囊收缩和胰腺外分泌的脑肠肽,可从狗和猫的小肠中提取的,可以引起胆囊收缩。 | |||
T15654 |
Ketohexokinase inhibitor 1
PF-06835919 |
Others | Others |
Ketohexokinase inhibitor 1 是一种酮己糖激酶抑制剂(对 KHK-C 和 KHK-A 的 IC50:分别为 8.4 nM 和 66 nM)。 | |||
T15286 |
Flindokalner
BMS-204352 |
Potassium Channel | Membrane transporter/Ion channel |
Flindokalner (BMS-204352) 是一种钾离子通道调节剂。它是大电导钙激活 K 通道正向调节剂。它是在 HEK293 细胞中表达的所有神经元 Kv7通道亚型的正调节剂。它在 Kv7.1 通道 (Ki=3.7 μM) 处显示负调节活性,并充当 GABAA 受体的负调节剂。它在体内显示出抗焦虑功效。 | |||
TP2500 |
Cholecystokinin (26-33) free acid
CCK (26-33) free acid |
cholecystokinin | GPCR/G Protein |
Cholecystokinin (26-33) free acid 是胆囊收缩素 (CCK) 的一部分, 是脊椎动物中枢神经系统中存在的 CCKB 型受体的高选择性配体,可诱导大鼠轻度味觉厌恶条件反射。 | |||
T70540 |
Pinokalant
LOE-908 |
SARS-CoV; TRP/TRPV Channel | Membrane transporter/Ion channel; Microbiology/Virology |
Pinokalant (LOE-908) 是一种新型非选性阳离子通道抑制剂。Pinokalant 在体内实验中可显著减少皮质梗死体积,可改善缺血半影区的代谢和电生理状态,可减少大鼠大脑中动脉闭塞后急性期磁共振图像上的病变大小。Pinokalant是一种潜在的SARS-CoV-2蛋白酶抑制剂,可用于研究脑卒中。 | |||
TP1899L1 |
Hemokinin 1 (human) acetate(491851-53-7 free base)
|
Neurokinin receptor | GPCR/G Protein; Neuroscience |
Hemokinin 1 (human) acetate(491851-53-7 free base) 是一种内源性 P 物质同系物,是速激肽 NK1 受体的选择性激动剂(NK1、NK3 和 NK2 受体的 IC50 值分别为 1.8、370 和 480 nM)。在体外对 B 细胞具有增殖和抗凋亡作用,在体内具有抗高血压作用。 | |||
TP1363L |
Neurokinin B acetate(86933-75-7 free base)
神经激肽 B醋酸盐,Neurokinin K |
Neurokinin receptor | GPCR/G Protein; Neuroscience |
Neurokinin B acetate(86933-75-7 free base) 是属于速激肽家族的神经激肽 B 的醋酸盐形式。神经激肽与神经激肽受体 1 (NK1R)、nk2r 和 NK3R 结合,并介导其生物学效应。 | |||
TP1008 |
Neurokinin A
α-Neurokinin,Substance K,神经激肽A,Neuromedin L |
Neurokinin receptor | GPCR/G Protein; Neuroscience |
Neurokinin A (NKA) 是速激肽家族的一种肽类神经递质,是人体气管道和胃肠道组织中的主要介体,可通过 NK-2受体发挥作用。 | |||
T13180 |
TOK-8801
|
Others | Others |
TOK-8801 是一种合成的二氢咪唑噻唑羧酰胺,具有免疫调节活性,通过去除 T 细胞消除抗体产生的刺激作用。 | |||
TP1114L |
Leucokinin VIII acetate
Leucokinin 8 |
Others | Others |
Leucokinin VIII acetate (Leucokinin 8) 是一种从蟑螂头部提取物中分离的利尿八肽。 | |||
T23077L |
Novokinin acetate
Novokinin acetate (358738-77-9 free base) |
RAAS | Endocrinology/Hormones |
Novokinin acetate 对 AT2 受体表现出亲和力,Ki 为 7 nM,其抗高血压和血管舒张活性被 AT2 受体拮抗剂 PD123319 阻断。 | |||
T20688L |
Leucokinin I acetate
Leucokinin I acetate(104600-89-7 Free base) |
Others | Others |
Leucokinin I acetate 是一种抗昆虫肌肽的抗血清。 | |||
T10056 |
Neurokinin antagonist 1
|
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
Neurokinin antagonist 1是一种有效的是神经肽拮抗剂,可用于研究神经系统疾病。 | |||
T76704 |
Tralokinumab
CAT-354,LP 0162 |
IL Receptor | Immunology/Inflammation |
Tralokinumab 是一种全人源 IgG4 单克隆抗体,对单独的 IL-13 亲和力较高。Tralokinumab 具有潜在的抗炎活性,可预防IL-13与受体相互作用和随后的下游信号传导,可用于研究特应性皮炎 (AD) 。 | |||
T11076 |
Dooku1
|
Others | Others |
Dooku1 是Yoda1 的类似物,是一种内源性Piezo1通道的选择性拮抗剂,能够抑制Yoda1 诱导的主动脉舒张。它在HEK 293 细胞以及HUVEC 中测得对2 μM Yoda1 诱导的钙离子流的IC50值分别为1.3 μM 和1.5 μM。 | |||
TP1772L |
Hemokinin 1 (mouse) acetate(208041-90-1 free base)
|
Neurokinin receptor | GPCR/G Protein; Neuroscience |
Hemokinin 1 (mouse) acetate(208041-90-1 free base) 是一种选择性兴奋剂 1 受体激动剂,对人 NK1 受体的 Ki 值为 0.175 nM,对人 NK2 受体的 Ki 值为 560 nM。 | |||
T22517 |
5,7-Dichlorokynurenic acid
5,7-二氯犬尿喹啉酸,5,7-dichlorokynurenic acid sodium,5,7-DCKA |
NMDAR | Neuroscience |
5,7-Dichlorokynurenic acid (5,7-dichlorokynurenic acid sodium) 是一种专门针对于NMDA 受体甘氨酸位点的竞争性拮抗剂(KB:65 nM)。它是犬尿酸的衍生物,可降低大鼠皮质细胞培养物中 NMDA 诱导的神经元损伤程度。 | |||
TP1385 |
Neurokinin A(4-10) TFA(97559-35-8 free base)
Neurokinin A(4-10) TFA |
Neurokinin receptor | GPCR/G Protein; Neuroscience |
Neurokinin A(4-10) TFA(97559-35-8 free base) 是一种速激肽 NK2 受体激动剂。 | |||
T76744 |
Enokizumab
MEDI-528 |
IL Receptor | Immunology/Inflammation |
Enokizumab (MEDI-528) 是一种针对白介素 IL-9 的单克隆抗体。Enokizumab 可用于研究哮喘疾病。 | |||
T32626 | Leiokinine A | ||
Leiokinine A is a novel 4-quinolinone alkaloid. | |||
T124484 | Kanokoside D | ||
Kanokoside D 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124484,CAS号为 64703-88-4。 | |||
T124485 | Kanokoside A | ||
Kanokoside A 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124485,CAS号为 64703-85-1。 | |||
T64680 | Neurokinin A trifluoroacetate | ||
Neurokinin A trifluoroacetate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64680。 | |||
T76885 | Sonelokimab | ||
Sonelokimab (ALX 0761; M 1095) 是三价纳米抗体,特异性结合人白介素(IL)-17A、IL-17F及人血清白蛋白VHH,由单价骆驼来源纳米抗体构成,展现于斑块型银屑病研究中的应用潜力。 | |||
T76731 | Gevokizumab | ||
Gevokizumab 是一种有效的抗 IL-1β抗体,通过变构机制负向调节 IL-1β信号。Gevokizumab 降低 IL-1β对 IL-1受体 I 型 (IL-1RI) 信号受体的结合亲和力,而不影响 IL-1反调节诱饵受体 (IL-1 受体 II 型)。 | |||
T75404 | Galcuronokinase (AtGalAK) | ||
Galcuronokinase (AtGalAK)属于GHMP激酶家族,催化ATP依赖的α-d-半乳糖醛酸(d-GalA)向α-d-半乳糖醛酸-1-磷酸(GalA-1-P)的转化。 | |||
T76427 |
(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B
|
||
(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B 是 Neurokinin B(Neurokinin Receptor) 的竞争性拮抗剂,pA2 为 5.5,对 Substance P 或 Neurokinin A 没有影响。 | |||
T76655 |
Prokineticin 2 Isoform 2 (human)
|
||
Prokineticin 2 Isoform 2 (human) 为一下丘脑神经肽,能减少食物摄入,并在啮齿动物的体温调节与能量代谢中发挥作用。此外,Prokineticin 2 对高血糖、代谢综合征 (MetS) 及肥胖研究具有潜在价值。 | |||
T80566 |
Temtokibart
|
||
Temtokibart为一种IgG1λ2抗体,靶向IL22RA1并进行人源化处理,由剔除谷氨酰胺合成酶基因的细胞所表达。 | |||
T126070 |
Epimedokoreanoside I
|
||
Epimedokoreanoside I 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126070,CAS号为 130756-11-5。 | |||
T126073 |
2-Oxokolavenol
|
||
2-Oxokolavenol 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T126073。 | |||
T24670 |
Protokylol
JB-251,Protokylolum,JB 251,JB251,Protoquilol |
||
Protokylol is a β-adrenergic receptor agonist. | |||
T33653 |
Neurokinin A (4-10), nle(10)-
10-Nle-neurokinin A (4-10) |
||
Neurokinin A (4-10), nle(10)- is a neurologically active peptide translated from the pre-protachykinin gene. Neurokinin A has many excitatory effects on mammalian nervous systems and on the mammalian inflammatory and pain responses. | |||
T30904 |
Cholecystokinin-J
CCK-J |
||
Cholecystokinin-J can be used in cholecystography, radiomanometry and biliary cinematography. | |||
T124931 |
Dihydroflavokawin B
|
||
T124612 |
Kusunokinin
|
||
Kusunokinin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124612。 | |||
T124999 |
Tsaokoin
|
||
Tsaokoin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124999。 | |||
T126549 |
Danshinspiroketallactone
|
||
Danshinspiroketallactone 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T126549。 | |||
TP2204 |
Cholecystokinin Octapeptide, desulfated
CCK Octapeptide, non-sulfated |
Others | Others |
Non-sulfated form of the C-terminal octapeptide of CCK | |||
TP2060 |
Conantokin G
|
||
GluN2B (formally NR2B) selective, competitive antagonist of the NMDA receptor. Blocks NMDA-evoked current in mouse cortical neurons (IC50 = 480 nM); also inhibits NMDA-evoked responses in oocytes expressing GluN2B (formally NR2B), but not GluN2A (formally | |||
T125690 |
Epimedokoreanin C
|
||
Epimedokoreanin C 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125690。 | |||
TP1772 |
Hemokinin 1 (mouse)
|
||
Hemokinin 1 (mouse) is a selective excitogen 1 receptor agonist with a Ki value of 0.175 nM for the human NK1 receptor and 560 nM for the human NK2 receptor. | |||
T83167 |
Adipokinetic Hormone (AKH) (24-32), locust TFA
|
||
Adipokinetic Hormone (AKH) (24-32), locust (TFA),是从蝗虫心脏分离的一种神经激素,调节飞行过程中的脂质利用。 | |||
T26116 |
Rokitamycin
|
||
Rokitamycin is a macrolide antibiotic produced from strains of Streptomyces kitasatoensis. | |||
T80915 |
Tyr0-Neurokinin A
|
||
Tyr0-Neurokinin A,一种神经肽,隶属于速激肽家族,作为Tacr2的激动剂,适用于胰岛素抵抗、肥胖和糖尿病研究领域。 | |||
T82470 |
Endokinin C
|
||
Endokinin C作为内皮激肽系列中的肽类成分,在疼痛途径中扮演神经递质或调节剂的角色。该化合物的预处理能有效抑制endokinin A/B引发的小鼠划痕行为以及对热的过敏反应。 | |||
T41029 |
Streptokinase
|
||
Streptokinase is a bacterial protein that acts as a plasminogen activator, commonly employed in the investigation of blood-clotting disorders. Its application extends to enhancing reperfusion blood flow after coronary artery occlusion. | |||
T125620 | Abbeokutone | ||
Abbeokutone 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125620,CAS号为 16836-28-5。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN2029 |
p-Hydroxy-5,6-dehydrokawain
4'-Hydroxydehydrokawain,4'-羟基-5,6-脱氢醉椒素 |
Others | Others |
p-Hydroxy-5,6-dehydrokawain (4'-Hydroxydehydrokawain) 是一种分离自 Kawain 的天然产物。 | |||
T3S0737 |
Flavokawain A
2'-羟基-4,4',6'-三甲氧基查耳酮,Flavokavain A |
Apoptosis; p38 MAPK | Apoptosis; MAPK |
Flavokawain A (Flavokavain A) 是 kava 提取物中的查耳酮,是一种抗癌试剂,具有抗肿瘤活性。它通过 Bax 蛋白依赖和线粒体依赖的凋亡途径诱导细胞凋亡,有潜力用于膀胱癌的相关研究。 | |||
TN1204 |
2,3-Dehydrokievitone
2,3-脱氢维酮 |
Antifungal | Microbiology/Virology |
2,3-Dehydrokievitone 是一种从刺桐属植物 Erythrina sacleuxii 中提取的一种异黄酮,具有抗菌活性,可通过降低α-溶血素表达来对抗耐甲氧西林金黄色葡萄球菌感染。 | |||
T4S0181 |
Hinokiflavone
日本扁柏黄酮,扁柏双黄酮 |
MMP; BCL; E1/E2/E3 Enzyme | Apoptosis; Proteases/Proteasome; Ubiquitination |
Hinokiflavone 是pre-mRNA 剪接活性的新型调节剂,通过抑制剪接体装配来阻止pre-mRNA 底物的剪接,特别是阻止 B complex 的形成。它是SUMO protease 蛋白酶抑制剂,能够抑制前哨蛋白特异性蛋白酶 1 的活性。 | |||
TN2008 |
Okanin
|
NF-κB; TLR | Immunology/Inflammation; NF-κB |
Okanin 是鬼针草中的一种有效成分,可通过抑制TLR4/NF-κB 信号通路减弱 LPS 诱导的小胶质细胞活化。 | |||
T5753 |
Flavokawain C
黄卡瓦胡椒素 C,卡瓦胡椒素C |
Apoptosis | Apoptosis |
Flavokawain C 是存在卡瓦胡椒根中的一种天然查尔酮,具有发展成为治疗结肠腺癌的化疗药物的潜力。它对 HCT 116 细胞作用的 IC50值为 12.75 μM。 | |||
TN1781 |
Isokurarinone
|
Others | Others |
Isokurarinone 是一种来自苦参的天然产物。 | |||
T3717 |
Hinokitiol
4-Isopropyltropolone,桧木醇,β-thujaplicin,β-桧木醇 |
DNA Methyltransferase; Virus Protease; Estrogen/progestogen Receptor; Nrf2 | Chromatin/Epigenetic; Endocrinology/Hormones; Immunology/Inflammation; Microbiology/Virology |
Hinokitiol (4-Isopropyltropolone) 是从日本扁柏中分离到的一种挥发油成分,可抑制紫外线 B 诱导的角质形成细胞凋亡,可调节雌激素受体信号传导并抑制人乳腺癌细胞的增殖。它具有抗感染、抗氧化及抗肿瘤等活性。 | |||
TN1788 |
Isookanin
|
Amylase | Metabolism |
Isookanin 在多种疾病领域有研究价值,包括肿瘤,皮疹,蛇和昆虫叮咬,糖尿病,腹泻。它可作为抗病毒剂对抗 HSV 和水痘带状疱疹病毒。它也具有抗氧化特性。 | |||
T3001 |
Honokiol
和厚朴酚,NSC 293100 |
ERK; HCV Protease; MEK; Akt; Autophagy | Autophagy; Cytoskeletal Signaling; MAPK; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome |
Honokiol (NSC-293100) 是厚朴提取物的活性成分,靶向多种信号分子,具有抗氧化,抗炎,抗血管生成和抗癌活性。它可抑制 Akt 的激活并增强 ERK1/ERK2 的磷酸化。 | |||
TN3972 |
Epimedokoreanin B
|
Apoptosis; Others; Antibacterial | Apoptosis; Microbiology/Virology; Others |
Epimedokoreanin B (EKB) 是一种从韩国淫羊藿中分离出的异戊烯化类黄酮,在人非小细胞肺癌(NSCLC)A549和NCI-H292细胞中展现出抗癌活性。Epimedokoreanin B 还具有抗炎和抗菌活性,可有清除 DPPH 自由基的活性,能以剂量依赖的方式抑制 MCF-7 和 HepG2 的增殖。Epimedokoreanin B 能显著抑制 N (δ) -(羧甲基)赖氨酸(CML)和 N (Ï) -(羧甲基)精氨酸(CMA)的形成,可通过抑制高级糖化终产物(AGEs)预防糖尿病的临床并发症。 | |||
T6S0735 |
Flavokawain B
黄卡瓦胡椒素B,Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone |
Apoptosis; Others | Apoptosis; Others |
Flavokawain B (Flavokavain B) 是从卡瓦醉椒的根提取物中,分离出的查尔酮。它是一种凋亡诱导剂,可抑制各种癌细胞株生长。它以极低的无毒浓度抑制人脑内皮细胞的迁移和血管形成,具有抗血管生成活性。 | |||
T10191L |
7-Chlorokynurenic acid
7-chloro-4-hydroxy-2-carboxyquinoline,7-氯犬尿酸,7-CKA |
GluR; NMDAR | Neuroscience |
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) 是一种有效的选择性 NMDA 受体拮抗剂,对甘氨酸 B 激动剂位点的 IC50 为 0.56 μM。 7-Chlorokynurenic acid 抑制谷氨酸再摄取到突触小泡中,Ki 为 0.59 μM,并在神经轴输送后显示出镇痛作用。 | |||
T4591 |
Dihydrokavain
Marindinin,二氢醉椒素,7,8-Dihydrokavain,7,8-Dihydrokawain |
Others | Others |
Dihydrokavain (Marindinin) 是一种具有抗焦虑作用的天然化合物。 | |||
TN7231 |
Di-O-methylhonokiol
Honokiol dimethyl ether |
Antioxidant | oxidation-reduction |
Di-O-methylhonokiol (Honokiol dimethyl ether) 是Magnolia grandiflora L 的酚类成分,具有抗微生物活性,对革兰氏阳性和抗酸细菌和真菌具有显著的抗氧化活性。 | |||
TN1406 |
Dihydrokaempferol
香橙素,Aromadendrin |
Apoptosis; BCL | Apoptosis |
Dihydrokaempferol (Aromadendrin) 是从紫荆花中分离得到的一种天然产物,诱导凋亡并抑制 Bcl-2 和 Bcl-xL 的表达,可以作为抗关节炎的良好新药候选。 | |||
T5715 |
(E)-Flavokawain A
(E)-1-(2-羟基-4,6-二甲氧基苯基)-3-(4-甲氧基苯基)-2-丙烯-1-酮,FLAVOKAVAIN A(P),卡瓦胡椒素A |
Apoptosis; P450 | Apoptosis; Metabolism |
(E)-Flavokawain A 是一种来自卡瓦提取物的新型查尔酮,通过参与 Bax 蛋白依赖性和线粒体依赖性凋亡途径诱导膀胱癌细胞凋亡,并抑制小鼠肿瘤生长,具有抗癌作用。 | |||
T75890 |
Conantokin G TFA
|
||
Conantokin G TFA 是一种 17 个氨基酸的肽,是一种有效,选择性和竞争性的 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂。Conantokin G TFA 抑制鼠皮质神经元中NMDA 诱发的电流,IC50为 480 nM,具有神经保护作用。 | |||
TN2697 |
2,3-Dihydrohinokiflavone
|
MMP; Parasite; Antifection | Microbiology/Virology; Proteases/Proteasome |
2,3-Dihydrohinokiflavone 是基质金属蛋白酶 (MMP) 基因表达的抑制剂,对利什曼原虫具有很强的活性,IC50 为 1.6 μM。 | |||
TN4302 |
Isokadsurenin D
|
Others | Others |
Isokadsurenin D是一种天然产物,属于五味子科南五味子属,其产品编号为 TN4302,CAS号为 147976-35-0。Isokadsurenin D可用作对照参考。 | |||
TN3954 |
ent-7alpha,9-Dihydroxy-15-oxokaur-16-en-19,6bet-olide
|
Others | Others |
ent-7alpha,9-Dihydroxy-15-oxokaur-16-en-19,6bet-olide 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3954,CAS号为 59885-89-1。 | |||
TN4089 |
Futokadsurin C
|
Others | Others |
Futokadsurin C can inhibit nitric oxide production by a murine macrophage-like cell line (RAW 264.7), which is activated by lipopolysaccharide and interferon-gamma. | |||
TN3946 |
ent-3-Oxokaurane-16,17-diol
|
Others | Others |
AKaurane-3,16,17-triol,ent-kaurane-3-oxo-16α,17-diol,and ent-16α,17-dihydroxyatisan-3-one are three kinds of toxic diterpenoids isolated from the roots of genus Euphorbia. | |||
T72901 |
Indolokine A5
|
||
Indolokine A5, L-半胱氨酸的分解代谢物, 是一种有效的AhR 激动剂。 | |||
TN6655 |
(1S,2S)-threo-Honokitriol
|
||
(1S,2S)-threo-Honokitriol是一种天然产物,属于木兰科木兰属,其产品编号为 TN6655,CAS号为 1099687-80-5。(1S,2S)-threo-Honokitriol可用作对照参考。 | |||
T16381 |
Okadaic acid
|
Others | Others |
Okadaic acid is a non-comepetitive, selective and reversible serine/threonine-specific protein phosphatases 1 (PP1), PP2A, and PP3 inhibitor (IC50s: 10-15 nM, 0.5 nM, and 4 nM, respectively). Okadaic acid is extracted from black sponges of the genus Halic | |||
TN6363 |
Tsaokoarylone
|
||
Tsaokoarylone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6363,CAS号为 811471-20-2。 | |||
TN3945 |
ent-3-Oxokauran-17-oic acid
|
Others | Others |
ent-3-Oxokauran-17-oic acid 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3945,CAS号为 151561-88-5。 | |||
TN5577 |
ent-9-Hydroxy-15-oxokauran-19-oic acid
|
||
ent-9-Hydroxy-15-oxokauran-19-oic acid 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5577,CAS号为 77658-45-8。 | |||
TN5172 |
Trichokaurin
|
Others | Others |
Trichokaurin是一种天然产物,属于唇形科香茶菜属,其产品编号为 TN5172,CAS号为 23811-50-9。Trichokaurin可用作对照参考。 | |||
T83309 |
5,22-Dioxokopsane
|
||
5,22-Dioxokopsane为源自Kopsia officinalis的单萜类吲哚生物碱。 | |||
TN1645 |
Flavokawain C
|
NADPH-oxidase; MAPK; AChR | Immunology/Inflammation; MAPK; Neuroscience |
Flavokawain C is a melanogenesis inhibitor, it inhibited melanogenesis with IC50 values of 6.9 μM. Flavokawain C has anti-tumor activity, it inhibited cell cycle and promoted apoptosis, associated with endoplasmic reticulum stress and regulation of MAPKs and Akt signaling pathways in HCT 116 human colon carcinoma cells. | |||
T82024 |
Isovaleroyl oxokadsuranol
|
||
Isovaleroyl oxokadsuranol为从Kadsura longipedunculata中提取的一种木脂素化合物。 | |||
TN2791 |
2-Oxokolavelool
|
Others | Others |
2-Oxokolavelool 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2791,CAS号为 221466-41-7。 | |||
TN6383 |
(+)-Hannokinol
|
||
(+)-Hannokinol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6383,CAS号为 408324-76-5。 | |||
T33786 |
Okilactomycin
YP 02908L-A,YP02908L-A,YP-02908L-A |
||
Okilactomycin is a biochemical. | |||
TN2964 | 3'-Methylflavokawin | Others | Others |
3'-Methylflavokawin shows cytotoxicity against HeLa cells, the IC 50 value comparable to xanthohumol (8.2-19.2 microM). | |||
TN5039 |
Sorokinianin
|
Antifection | Microbiology/Virology |
Sorokinianin is a phytotoxin, it has antifungal activity, it is highly effective in suppressing spore germination of F. solani (75%) at 100 ug/ml concentration. | |||
TN4303 |
Isokaempferide
|
ATPase; Potassium Channel; Calcium Channel; TNF; Prostaglandin Receptor | Apoptosis; GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism |
Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by reducing neutrophil degranulation, myeloperoxidase activity, mediators as well as TNF-alpha secretion. Isokaempferide is used as a bronchodilator, can induce relaxation of guinea-pig isolated trachea. | |||
TN6358 |
meso-Hannokinol
|
||
meso-Hannokinol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6358,CAS号为 79055-11-1。 | |||
TN5021 |
Sikokianin C
|
||
Sikokianin C 是一种从 Wikstroemia sikokiana 中分离得到的双黄酮类化合物。Sikokianin C 是一种选择性胱硫硫氨酸β-合成酶抑制剂,具有抗肿瘤活性,可用于治疗人结肠癌。 | |||
TN3931 |
ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid
|
ERK; BCL; p38 MAPK; NF-κB; Caspase; JNK; p53 | Apoptosis; MAPK; NF-κB; Proteases/Proteasome |
Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid has anti-cancer activity, it induces apoptosis of human malignant cancer cells, it also inhibits hepatocellular carcinoma in vitro and in vivo via stabilizing IkBα. | |||
TN5164 |
trans-Hinokiresinol
|
IL Receptor; TNF; NOS; LTR | Apoptosis; Immunology/Inflammation |
Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils, it has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphylaxis reaction. Hinokiresinol (trans-hinokiresinol) and nyasol (cis-hinokiresinol) are estrogen | |||
TN2987 |
3Alaph-Tigloyloxypterokaurene L3
|
Others | Others |
3Alaph-Tigloyloxypterokaurene L3 is a natural product from Wedelia trilobata. | |||
TN4182 |
Hannokinol
|
Others | Others |
(+)-Hannokinol and MESO-hannokinol can significantly inhibit lipopolysaccharide-induced nitric oxide production in BV2 microglial cells at concentrations ranging from 1 microM to 100 microM. | |||
TN1228 |
25S-Inokosterone
|
TNF | Apoptosis |
25S-Inokosterone exhibits potent inhibition against TNF-expression levels in A23187 plus phorbol-myrisrate acetate-induced RBL-2H3 cells. 25S-Inokosterone has excellent anti-atopy activity, thus 25S-Inokosterone could be used to a large range of functional anti-atopy cosmetics. | |||
TN2921 |
3alpha-Cinnamoyloxypterokaurene L3
|
Others | Others |
3alpha-Cinnamoyloxypterokaurene L3 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2921,CAS号为 79406-13-6。 | |||
TN3054 |
4-O-Demethylisokadsurenin D
|
Others | Others |
4-O-Demethylisokadsurenin D 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3054,CAS号为 89104-59-6。 | |||
TN2920 |
3alpha-Angeloyloxypterokaurene L3
|
Others | Others |
3alpha-Angeloyloxypterokaurene L3 is a natural product from Wedelia trilobata. | |||
TN4854 |
Pterokaurene L3
|
Others | Others |
Pterokaurene L3 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4854,CAS号为 77658-38-9。 | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-06019 |
EMMPRIN/CD147 Protein, Cynomolgus, Recombinant (His)
basigin (Ok blood group) |
Cynomolgus | HEK293 Cells |
EMMPRIN/CD147 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.4 kDa and the accession number is XP_005587354.1. | |||
TMPY-00684 |
EMMPRIN/CD147 Protein, Human, Recombinant (hFc)
EMMPRIN,CD147,OK,M6,TCSF,Basigin,5F7,basigin (O... |
Human | HEK293 Cells |
EMMPRIN/CD147 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is P35613-2. | |||
TMPY-00685 |
EMMPRIN/CD147 Protein, Human, Recombinant
CD147,TCSF,5F7,Basigin,OK,M6,basigin (Ok b... |
Human | HEK293 Cells |
EMMPRIN/CD147 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.7 kDa and the accession number is P35613-2. | |||
TMPK-01334 |
EMMPRIN/CD147 Protein, Canine, Recombinant (His)
Basigin,BSG,M6,OK,5F7,TCSF,CD147 |
Canine | HEK293 Cells |
CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation of extracellular matrix (ECM) remodeling during physiological and pathological processes including wound healing, inflammatory diseases, and cancer. CD147 is a diagnostic and therapeutic target in cancer and inflammatory diseases, either directly or indirectly, by targeting CD147 partners. | |||
TMPY-01315 |
EMMPRIN/CD147 Protein, Mouse, Recombinant (His & hFc)
AI325119,CD147,basigin (Ok blood group),HT-7,AI1154... |
Mouse | HEK293 Cells |
EMMPRIN/CD147 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 48.6 kDa and the accession number is P18572-2. | |||
TMPY-01316 |
EMMPRIN/CD147 Protein, Mouse, Recombinant (His)
CD147,HT-7,AI115436,AI325119,EMMPRIN,basigin (Ok bl... |
Mouse | HEK293 Cells |
EMMPRIN/CD147 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30 kDa and the accession number is P18572-2. | |||
TMPH-00262 |
Bovine coronavirus (strain OK-0514) Spike glycoprotein (Yeast, His)
E2,Spike glycoprotein,Peplomer protein,S,S glycoprotein |
BCoV | P. pastoris (Yeast) |
Bovine coronavirus (strain OK-0514) Spike glycoprotein (Yeast, His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 36.5 kDa and the accession number is Q9QAQ8. | |||
TMPH-00263 |
Bovine coronavirus (strain OK-0514) Spike glycoprotein (His)
Peplomer protein,S,S glycoprotein,E2,Spike glycoprotein |
BCoV | HEK293 Cells |
Bovine coronavirus (strain OK-0514) Spike glycoprotein (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 37.2 kDa and the accession number is Q9QAQ8. | |||
TMPH-00251 |
Bovine coronavirus (strain OK-0514) Nucleoprotein/NP Protein (His)
Protein N,Nucleocapsid protein,N,NC,Nucleoprotein |
BCoV | E. coli |
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Bovine coronavirus (strain OK-0514) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 50.3 kDa and... | |||
TMPH-00244 |
Bovine coronavirus (strain OK-0514) Non-structural Protein 4b (His & SUMO)
4.8 kDa accessory protein,ns4.8,Non-structural protein of 4.... |
BCoV | E. coli |
Bovine coronavirus (strain OK-0514) Non-structural Protein 4b (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 17.9 kDa and the accession number is P0C2R8. | |||
TMPH-00242 |
Bovine coronavirus (strain OK-0514) Non-structural Protein 5a (His)
ns12.7,12.7 kDa accessory protein,Non-structural protein of ... |
BCoV | E. coli |
N/A. Bovine coronavirus (strain OK-0514) Non-structural Protein 5a (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 15.1 kDa and the accession number is Q9QAQ5. | |||
TMPJ-00160 |
EMMPRIN/CD147 Protein, Human, Recombinant (His)
5F7,TCSF,OK Blood Group Antigen,Tumor Cell-Derived ... |
Human | HEK293 Cells |
Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane glycoprotein with different forms, resulting from different modes of glycosylation and N-terminal sequence variants. EMMPRIN can be expressed in breast cancer, oral squamous cell carcinoma, glioma, lymphoma, lung, bladder, and melanoma carcinomas cells. EMMPRIN promotes invasion,... | |||
TMPY-00904 |
Urokinase/uPA Protein, Human, Recombinant (His)
u-PA,QPD,BDPLT5,ATF,UPA,plasminogen activator, urok... |
Human | HEK293 Cells |
Urokinase/uPA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is A0A024QZM9. | |||
TMPY-04394 |
Glucokinase Protein, Human, Recombinant
glucokinase (hexokinase 4),HXKP,MODY2,FGQT... |
Human | E. coli |
Glucokinase belongs to the bacterial glucokinase family. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but ... | |||
TMPK-01192 |
Varicella-zoster virus (strain Oka vaccine) Envelope glycoprotein E Protein (His)
Envelope glycoprotein E,ORF68,gE |
Varicella-zoster virus (strain Oka vaccine) | HEK293 Cells |
VZV glycoprotein E (gE) is most abundantly expressed on the surface of infected cells, and is an essential component for virus replication and cell-to-cell transmission. It is also the main target of virus-specific antibodies and T cell responses that is often selected as vaccine candidate antigen. | |||
TMPH-02385 |
Lake Victoria marburgvirus (MARV) (strain Musoke-80) VP30 Protein (His & Myc)
|
MARV | E. coli |
Acts as a transcription anti-termination factor immediately after transcription initiation, but does not affect transcription elongation. This function has been found to be dependent on the formation of an RNA secondary structure at the transcription start site of the first gene. | |||
TMPH-01211 |
DGUOK Protein, Human, Recombinant (His & SUMO)
Deoxyguanosine kinase, mitochondrial,Deoxyadenosine kinase, ... |
Human | E. coli |
Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs. Widely used as target of antiviral and chemotherapeutic agents. | |||
TMPH-02383 |
Lake Victoria marburgvirus (MARV) (strain Musoke-80) VP35 Protein (His)
|
MARV | E. coli |
Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling. | |||
TMPY-01502 |
Influenza A H5N3 (A/duck/Hokkaido/167/2007) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H5N3 | HEK293 Cells |
Influenza A H5N3 (A/duck/Hokkaido/167/2007) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is B1AHS0. | |||
TMPY-06867 |
Varicella-zoster virus (VZV) (strain Oka vaccine) gH & gL Heterodimer Protein
|
VZV | CHO Cells |
Varicella-zoster virus (VZV) (strain Oka vaccine) gH & gL Heterodimer Protein is expressed in CHO mammalian cells. The predicted molecular weight is 85.17 kDa. | |||
TMPH-02335 |
RIOK3 Protein, Human, Recombinant (E. coli, His)
|
Human | E. coli |
RIOK3 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 62.7 kDa and the accession number is O14730. | |||
TMPY-01503 |
Influenza A H5N3 (A/duck/Hokkaido/167/2007) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H5N3 | HEK293 Cells |
Influenza A H5N3 (A/duck/Hokkaido/167/2007) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is B1AHS0. | |||
TMPY-04407 |
LOK Protein, Human, Recombinant (His)
serine/threonine kinase 10,PRO2729,LOK |
Human | E. coli |
Serine / threonine-protein kinase 1, also known as Lymphocyte-oriented kinase, STK1 and LOK, belongs to the protein kinase superfamily, STE Ser / Thr protein kinase family and STE2 subfamily. Protein kinases constitute a large superfamily of enzymes with key regulatory functions in nearly all signal transmission processes of eukaryotic cells. The Ste2 family of serine/threonine kinases plays an important role in numerous cellular functions such as growth, apoptosis, and morphogenesis. STK1 is si... | |||
TMPH-02747 |
Ketohexokinase/KHK Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Ketohexokinase/KHK Protein, Mouse, Recombinant (His) is expressed in E. coli. | |||
TMPH-03160 |
Glucomannokinase Protein, Prevotella bryantii, Recombinant
|
Prevotella bryantii | E. coli |
The enzyme has great affinity for glucose and mannose. Glucomannokinase Protein, Prevotella bryantii, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 2.7 kDa and the accession number is P82680. | |||
TMPH-02093 |
RIOK3 Protein, Human, Recombinant (His)
|
Human | Baculovirus Insect Cells |
RIOK3 Protein, Human, Recombinant (His) is expressed in Baculovirus. | |||
TMPY-00519 |
Gastrokine 1 Protein, Human, Recombinant (His)
UNQ489/PRO1005,CA11,foveolin,BRICD1,AMP18,gastrokin... |
Human | Baculovirus Insect Cells |
Gastrokine 1 (GKN1) belongs to the BRICHOS domain family and plays a major role in maintaining gastric mucosa integrity. GKN1 is highly expressed in gastric tissue and is secreted into the stomach but is not expressed in gastric cancer. GKN1-mediated inhibition of APP processing might represent a new approach for the prevention and therapy of Alzheimer's disease (AD). In the presence of GKN2, GKN1 loses its ability to decrease cell proliferation, induce apoptosis, and inhibit epigenetic alterati... | |||
TMPK-00972 |
PK-1/PROK1 Protein, Mouse, Recombinant (hFc)
PROK1,Mambakine,Prokineticin-1,EG-VEGF |
Mouse | HEK293 Cells |
PK-1 (Ac10) is a baculovirus-encoded serine/threonine kinase,a pk-1 knockout AcMNPV failed to produce infectious progeny, while the pk-1 repair virus could rescue this defect.the kinase activity of PK-1 is essential in regulating viral propagation. Electron microscopy revealed that pk-1 deletion affected the formation of normal nucleocapsids.PK-1 appears to phosphorylate some viral or cellular proteins that are essential for DNA packaging to regulate nucleocapsid assembly. | |||
TMPH-00726 |
Ribokinase Protein, E. coli, Recombinant (His)
|
E. coli | E. coli |
Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | |||
TMPY-00274 |
Enterokinase Protein, Bovine, Recombinant (His)
transmembrane protease, serine 15 |
Bovine | P. pastoris (Yeast) |
Enterokinase Protein, Bovine, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 27.1 kDa and the accession number is P98072-1. | |||
TMPY-06855 |
Varicella-zoster virus (VZV) (strain Oka vaccine) Glycoprotein B/gB Protein
|
VZV | CHO Cells |
Varicella-zoster virus (VZV) is a highly fusogenic virus, but the degree of fusion is dependent on the cell substrate in which the virus is propagated. Varicella-zoster virus (VZV) is classified as an alphaherpesvirus based on its growth characteristics and its ability to become latent in the nervous system of the host. Like all known herpesviruses, VZV encodes a homolog of glycoprotein B (gB). Glycoprotein B (gB) is the most conserved entry glycoprotein among herpesviruses with an amino acid se... | |||
TMPY-04626 |
Enterokinase/EK Protein, Bovine, Recombinant
EK, Enterokinase, PRSS7, Enteropeptidase, EC 3.4.21... |
Bovine | P. pastoris (Yeast) |
Enterokinase is a member of the trypsin family of serine proteases. The precursor protein is cleaved into two chains which then forms a heterodimer linked by a disulfide bond. The heavy chain anchors enterokinase in the intestinal brush border membrane and the light chain is the catalytic subunit, which initiates conversion activation of a subset of pancreatic proteolytic proenzymes. Enterokinase is the physiological activator of trypsinogen and has a specificity for the sequence (Asp)4-Lys-Ile.... | |||
TMPY-04770 |
RIOK1 Protein, Human, Recombinant (His & GST)
AD034,RRP10,bA288G3.1,RIO kinase 1 |
Human | Baculovirus Insect Cells |
RIOK1, also known as RIO kinase 1, is a member of the RIO family of atypical serine protein kinases first characterized in yeast. RIOK1 and RIOK2 proteins are present in organisms from Archaea to humans. RIOK1 functions as a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity. RioK1 and pICln bind to PRMT5 in a mutually exclusive fashion. This results in a PRMT5-WD45/MEP5 core structure ... | |||
TMPH-01585 |
Ketohexokinase/KHK Protein, Human, Recombinant (GST)
|
Human | E. coli |
Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate. Ketohexokinase/KHK Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 59.7 kDa and the accession number is P50053. | |||
TMPY-04399 |
TAOK3 Protein, Human, Recombinant (aa 1-411, His & GST)
DPK,MAP3K18,TAO kinase 3,JIK |
Human | Baculovirus Insect Cells |
Serine/threonine-protein kinase TAO3, also known as cutaneous T-cell lymphoma-associated antigen HD-CL-9, CTCL-associated antigen HD-CL-9, Dendritic cell-derived protein kinase, JNK / SAPK-inhibitory kinase, Jun kinase-inhibitory kinase, Kinase from chicken homolog A, Thousand and one amino acid protein 3, JIK, TAOK3 and MAP3K18, is cytoplasm and peripheral membrane protein which belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE2 subfamily. Protein kinases are ... | |||
TMPY-04504 |
Urokinase/uPA Protein, Rat, Recombinant (His)
plasminogen activator, urokinase |
Rat | HEK293 Cells |
Urokinase/uPA Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.3 kDa and the accession number is A6KKR2. | |||
TMPH-03683 |
Varicella-zoster virus (strain Oka vaccine) glycoprotein H/gH Protein (His)
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HHV-3 | E. coli |
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. Varicella-zoster virus (strain Oka vaccine) glycoprotein H/gH Protein (His) is expressed in E... | |||
TMPH-03685 |
Varicella-zoster virus (strain Oka vaccine) glycoprotein L/gL Protein (His & Myc)
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HHV-3 | E. coli |
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form. Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH. Varicella-zoster virus (strain Oka vaccine) glycoprotein L/gL Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The... | |||
TMPY-02945 |
Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His)
PK1,EGVEGF,PRK1,prokineticin 1 |
Human | Baculovirus Insect Cells |
EG-VEGF, also known as prokineticin-1, is a member of the AVIT (prokineticin) family. Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. EG-VEGF can be detected in the steroidogenic glands, ovary, testis, adrenal and placenta. EG-VEGF has little or no effect on a variety of other endothelial and non-endothelial cell types. It induces proliferation, migration and fenestration (the formation of membrane discontinuities) i... |