168
20
2
2
63
Cat. No. | Product Name | ||
---|---|---|---|
L9001 | 食品添加剂化合物库 | 425 compounds | |
425种食品添加剂的集合 | |||
L6030 | 天然产物衍生物虚筛化合物库 | 163000 compounds | |
16.3万种天然产物衍生物,并且在持续增加中; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0002 |
Phosphatase Inhibitor Cocktail I (100× ddH2O)
磷酸酶抑制剂 Cocktail I (100× ddH2O) |
Solution (100× in <em>dd</em>H2O) | Acid Phosphatase, Alkaline phosphatase, PTPs, ATPases |
C0046 |
RIPA Lysis Buffer (Middle)
RIPA裂解液(中) |
Solution in bottle |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8978 |
DD1
3,3'-Diamino-4'-methoxyflavone,HUN85111 |
Proteasome | Proteases/Proteasome; Ubiquitination |
DD1 (HUN85111) 是一种蛋白酶体抑制剂,可诱导人髓系肿瘤选择性凋亡。 | |||
T69274 |
DD-161515
|
||
DD-161515 is a VR1 antagonist. | |||
T31229 |
DD-3305
|
||
DD-3305 is a biochemical. | |||
T35481 |
DD 03-171
|
||
Potent and selective BTK Degrader (IC50 = 5.1 nM); degrades BTK in a proteasome- and CRBN-dependent manner. Suppresses BTK signaling and proliferation in mantle cell lymphoma (MCL) cells by degrading BTK, IKFZ1, and IKFZ3 (3 validated targets in B-cell malignancies). Also degrades Ibrutinib (Cat. No. 6813) -resistant C481S-BTK mutant cancer cells. Exhibits no binding against a panel of 468 kinases at 1 μM. Reduces tumor burden and extends survival in lymphoma patient-derived xenograft models. | |||
T71246 |
DD04107
|
||
DD04107 is a novel inhibitor of α-calcitonin gene-related peptide (α-CGRP) exocytotic release from primary sensory neurons, selectively interacting with Synaptotagmin 1. | |||
T74102 | DD-03-156 | ||
DD-03-156 是 CDK17和LIMK2的有效选择性降解剂。DD-03-156的选择性和效力非常好,为开发降解CDK17的化学探针提供了一个先进的起点。DD-03-156 是CDK17和LIMK2的有效选择性降解剂。DD-03-156的选择性和效力非常好,为开发降解CDK17的化学探针提供了一个先进的起点。 | |||
T19688 |
Lodenosine
FddA,3'-dideoxyarabinosyladenine,Fddl,2'-F-dd-ara-A,2'-Fluoro-2',DDG-1 |
||
Lodenosine is an inhibitor of RNA-directed DNA polymerase, and potentially for the treatment of HIV. | |||
T71244 | AM-461 | ||
AM-461 is a DP2 receptor antagonist. | |||
T10984 |
DDR-TRK-1
|
Discoidin Domain Receptor (DDR) | Tyrosine Kinase/Adaptors |
DDR-TRK-1 是 DDR1的一个选择性抑制剂,其 IC50 值为 9.4 nM。DDR-TRK-1 也抑制 TRK 激酶家族。 | |||
T27583 |
IDD388
IDD-388,IDD 388 |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
IDD388 是一种具有选择性和高效性的醛糖还原酶 (ALR2) 抑制剂,具有抗肿瘤活性,抑制 ALR1 受体。 | |||
T23973 |
DDD100097
DDD 100097,DDD-100097 |
Others | Others |
DDD100097 是一种有效的 N-肉豆蔻醇转移酶抑制剂,对布氏锥虫具有潜在的抑制作用,可用于研究神经系统疾病。 | |||
T39030 |
HBDDE
|
Apoptosis; PKC | Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling |
HBDDE 是一种具有选择型号的同工酶 PKCα 和 PKCγ 抑制剂,其 IC 50 s 分别为 43 μM 和 50 μM。HBDDE 对 PKCα/PKCγ 的亲和力高于 PKCδ、PKCβI 和 PKCβII 同工酶。HBDDE 是鞣花酸的一种衍生物,可诱导神经细胞凋亡。 | |||
T73253 |
EIDD-2749
4'-Fluorouridine,4'-FlU ; 4'-Fluorouridine,4'-FlU |
||
EIDD-2749 (4'-Fluorouridine) 是一种口服有效的RdRp 抑制剂。EIDD-2749 能有效抑制RSV 和SARS-CoV-2的复制。EIDD-2749 还表现出抗HCV 和淋巴细胞性脉络丛脑膜炎病毒 (LCMV) 的活性。EIDD-2749 是一种很有潜力的COVID-19口服治疗候选剂,也适用于其他 RNA 病毒的研究。 | |||
T13601 |
CDD3506
1-TRITYL-1H-IMIDAZOL-4-AMINE |
P450 | Metabolism |
CDD3506 (1-TRITYL-1H-IMIDAZOL-4-AMINE) 能够诱导肝CYP3A 的活动,增强高密度脂蛋白胆固醇的水平。 | |||
T7440 |
p,p'-DDE
p,p'-dichlorodiphenyldichloroethylene,4,4'-DDE,Dichlorodiphenyldichloroethylene,2,2-双(4-氯苯基)-1,1-二氯乙烯 |
Androgen Receptor; Drug Metabolite | Endocrinology/Hormones; Metabolism |
p,p'-DDE (p,p'-dichlorodiphenyldichloroethylene) 是持久性 DDT 的主要代谢物。4,4'-DDE 是一种有效的雄激素受体拮抗剂,IC50=5 μM,Ki=3.5 μM。 | |||
T10985 |
DDR Inhibitor
|
Discoidin Domain Receptor (DDR) | Tyrosine Kinase/Adaptors |
DDR Inhibitor 是一种高效的盘状结构域受体 (discoidin domain receptor) 抑制剂,对 DDR2 的 IC50 值为 3.3 nM,在浓度为 1.5 nM 时,对 DDR1 有 53% 的抑制作用。 | |||
T80662 |
CDD0102 HCl
CDD0102A HCl |
AChR | Neuroscience |
CDD0102 HCl 是一种具有选择性和有效的 M1 毒蕈碱 (Muscarinic) 受体激动剂,可用于治疗阿尔兹海默症。 | |||
T3337 |
Ddr1-In-1
|
Discoidin Domain Receptor (DDR) | Tyrosine Kinase/Adaptors |
DDR1-IN-1 是一种特异性的 DDR1 受体酪氨酸激酶抑制剂,选择性是 DDR2 的 3 倍左右。 | |||
T13602 |
CDDO-2P-Im
CDDO-2-P-Im |
Others | Others |
CDDO-2P-Im 在小鼠肺癌模型中显示出化学预防作用并降低了肺肿瘤的大小和严重程度。 | |||
T60487 |
DDO-7263
|
Nrf2 | Immunology/Inflammation |
DDO-7263 是一种 1,2,4-Oxadiazole 衍生物, 通过与 Rpn6 结合上调 Nrf2,从而阻断 26S 蛋白酶体的组装和随后Nrf2 的泛素化降解。DDO-7263 是一种有效的Nrf2激活剂,能够激活 Nrf2-ARE 信号通路并发挥抗炎活性。 | |||
TQ0120 |
CDDO-Im
RTA-403,CDDO-Imidazolide,TP-235 |
Others; Ferroptosis; Nrf2; PPAR | Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Others |
CDDO-Im (TP-235) 是一种 Nrf2和 PPAR 的激活剂,对 PPARα 和 PPARγ 的 Ki 分别为232 nM 和 344 nM。 | |||
T5700 |
PDD00017273
|
Others | Others |
PDD00017273 是一种有效的放射增敏作用(二磷酸腺苷核糖)的水解酶 (PARG) 抑制剂,具有抗肿瘤或活性。PDD00017273 具有放射增敏作用,可用于研究上皮性卵巢。 | |||
T13600 |
CDD3505
4-nitro-1-trityl-1H-imidazole |
P450 | Metabolism |
CDD3505 (4-nitro-1-trityl-1H-imidazole) 能够诱导肝CYP3A 的活动,增强高密度脂蛋白胆固醇的水平。 | |||
T72058L |
CDD-1102 HCl
CDD-1102 HCl(2757619-84-2 Free base) |
Epigenetic Reader Domain | Chromatin/Epigenetic |
CDD-1102 HCl 是一种新型BRDT-BD4 / BRD2-BD1302选择性抑制剂,在体内外实验中显示出非激素避孕潜力。 | |||
T39356 |
PDD00017272
PDD-00017272 |
Others | Others |
PDD00017272 (34f) 是一种高效的聚(ADP-核糖)糖水解酶 (PARG)抑制剂,在生化测定中的 EC50 值为 4.8 nM,在细胞 POM 中的 EC50 值为 9.2 nM。 | |||
T8334 |
CADD522
MFCD00167693,3-{[(3,4-二氯苯基)氨基]羰基}二环[2.2.1]庚-5-烯-2-羧酸 |
Others | Others |
CADD522 (MFCD00167693) 是 runt 相关转录因子-2 (RUNX2)-DNA 结合的抑制剂(IC50:10 nM),具有抗肿瘤作用。 | |||
T11095L |
DREADD agonist 21
|
5-HT Receptor; Adrenergic Receptor; AChR; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
DREADD agonist 21 是一种人毒蕈碱乙酰胆碱 M3 受体激动剂,EC50为 1.7 nM。 | |||
T26726 |
AzddMeC
CS-92,Azidodideoxymethylcytidine,Az-Dcme |
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
AzddMeC (Az-Dcme) 是一种具有口服活性、高效性和选择性的 HIV-1 逆转录酶和 HIV-1 复制抑制剂,具有抗逆转录病毒活性。AzddMeC 可用于研究 HIV-1 感染。 | |||
T69757 |
PDDC inhibitor
|
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
PDDC inhibitor (Phenyl (R)-(1-(3-(3,4-dimethoxyphenyl)-2,6-dimethylimidazo[1,2-b]pyridazin-8-yl)pyrrolidin-3-yl)carbamate) 是一种具有选择性和高效性的 nSMase2 抑制剂 ,可用于研究 HIV 感染。 | |||
T5402 |
DDR1-IN-2
DDR1 inhibitor 7rh |
Discoidin Domain Receptor (DDR) | Tyrosine Kinase/Adaptors |
DDR1-IN-2 (DDR1 inhibitor 7rh) 是盘状结构域受体 1 抑制剂 (IC50:13.1 nM),对 DDR2 的抑制作用相对较弱 (IC50:203 nM)。 | |||
T67797 |
DDG-39
1-(2,3-dideoxy-2-fluoropentofuranosyl)cytosine |
Antiviral; HBV; HIV Protease | Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome |
DDG-39 (1-(2,3-dideoxy-2-fluoropentofuranosyl)cytosine)具有抗病毒活性,在细胞培养中具有有效的选择性抗 HIV-1 和HBV 活性。平均抗病毒 IC50为0.61μM。 | |||
T15082 |
DDAO
|
Others | Others |
DDAO 是有潜在用途的近红外红色荧光探针,其激发波长 (600-650 nm) 和长发射波长 (λem = 656 nm)可以调节。它可用于不同酶活性的检测,如 β-半乳糖苷酶,羧酸酯酶 2,硫酸酯酶,蛋白质磷酸酶 2A,人白蛋白和酯酶。 | |||
T27135 |
DDD85646
DDD 85646,DDD-85646 |
Parasite | Microbiology/Virology |
DDD85646 是 T. brucei N-myristoyltransferase 的抑制剂,Ki 为 1.44 nM,IC50 为 2 nM,EC50 为 2 nM。 hNMT 的 IC50 为 4 nM。 | |||
T23974 |
DDRI-18
DDRI18,DDRI 18 |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
DDRI-18 是一种调节 DNA 损伤反应的新型小分子抑制剂,具有增敏活性和抗癌活性,抑制非同源末端连接 (NHEJ) DNA 修复过程,增强抗癌 DNA 损伤化合物的细胞毒性作用。 | |||
T8498 |
EIDD-1931
Beta-d-N4-hydroxycytidine |
Virus Protease; HCV Protease; SARS-CoV; Topoisomerase | DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome |
EIDD-1931 (Beta-d-N4-hydroxycytidine) 是一种核苷类抗病毒试剂 ,可抑制丙型肝炎病毒、基孔肯亚病毒和委内瑞拉马脑炎病毒的复制活性。 | |||
T11279 |
FGFR1/DDR2 inhibitor 1
|
Discoidin Domain Receptor (DDR); FGFR; Others | Angiogenesis; Others; Tyrosine Kinase/Adaptors |
FGFR1/DDR2 inhibitor 1 是一种具有口服活性的成纤维细胞生长因子受体 1 和盘状蛋白域受体 2 的抑制剂,能够抑制 FGFR1 (IC50:31.1 nM) 和 DDR2 (IC50:3.2 nM),具有抗肿瘤作用。 | |||
T10733 |
CDDO-EA
TP319,CDDO ethyl amide,RTA 405 |
Nrf2 | Immunology/Inflammation |
CDDO-EA (CDDO ethyl amide) 是 Nrf2/抗氧化反应元件的激活剂。 | |||
T9202 |
DDO-5936
|
HSP | Cytoskeletal Signaling; Metabolism |
DDO-5936 是一种特异性Hsp90-Cdc37 PPI 抑制剂,可研究大肠癌。 | |||
T13603 |
CDDO-3P-Im
|
Necroptosis | Apoptosis |
CDDO-3P-Im 是一种具有口服活性的坏死性凋亡抑制剂,具有化学预防作用。 CDDO-3P-Im 可用于有关缺血/再灌注的研究。 | |||
T13604 |
CDDO-dhTFEA
|
Others; NF-κB; Nrf2 | Immunology/Inflammation; NF-κB; Others |
CDDO-dhTFEA 是合成的齐墩果烷三萜化合物,可有效激活Nrf2并抑制促炎转录因子NF-κB。 它可以恢复高血压 (MAP),提高 Nrf2 及其靶基因的表达,抑制 NF-κB 的活化和转化生长因子-β 途径,并减少慢性肾病 (CKD) 大鼠的肾小球硬化,间质纤维化和炎症。 | |||
T10983L |
DDP-38003 dihydrochloride
|
Histone Demethylase | Chromatin/Epigenetic |
DDP-38003 dihydrochloride 是具有口服活性的KDM1A/LSD1抑制剂,IC50 值为 84 nM。 | |||
T37818 |
bPiDDB
N,N'-Dodecylbis-Picolinium Bromide |
AChR | Neuroscience |
bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) 是一种烟碱样受体 (nAChR) 拮抗剂。 | |||
T64346 |
DDAC
Quaternium 12 |
Antibacterial | Microbiology/Virology |
DDAC (Quaternium 12), also known as Didecyldimethylammonium chloride, is a dialkyl-quaternary ammonium compound widely utilized in various products due to its bactericidal, virucidal, and fungicidal characteristics. | |||
TP1545L1 |
FFAGLDD amine salt
|
Others | Others |
FFAGLDD amine salt 是MMP9选择性裂解肽,用于多柔比星(DOX)的胞浆递送,实现时间和空间可控的缓慢药物递送和释放。 | |||
T8309 |
EIDD-2801
Molnupiravir |
SARS-CoV | Microbiology/Virology |
EIDD-2801 (Molnupiravir) 是核糖核苷类似物 N 4-羟基胞苷 (EIDD-1931) 的异丙酯前药,已显示出广泛的流感病毒和多种冠状病毒活性。 | |||
T10986 | DDX3-IN-1 | Others | Others |
DDX3-IN-1 is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC50 of 50 and 36 μM for HIV and HCV, respectively. Antiviral activity. | |||
T10731 |
CDD0102
CDD0102A |
AChR | Neuroscience |
CDD0102 is a potent agonist of M1 Muscarinic receptor. | |||
T74500 | FSDD3I | ||
FSDD3I 是一种配体,特别是针对白蛋白结合成纤维细胞活化蛋白 (FAP) 的。它能够以68Ga 和177Lu 进行标记,进而应用于单光子发射计算机断层扫描 (SPECT) 成像技术。 | |||
T74498 | FSDD0I | ||
FSDD0I为一种与白蛋白结合的成纤维细胞活化蛋白(FAP)配体,能够与68Ga和177Lu标记,用于单光子发射计算机断层扫描(SPECT)成像。 | |||
TP1545 |
FFAGLDD
|
Others | Others |
FFAGLDD 是 MMP9 选择性切割肽,用于多柔比星 (DOX) 的胞浆递送,实现时间和空间控制的缓慢药物递送和释放。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3878 |
Raddeanin A
NSC382873,竹节香附素A,Anemodeanin A,Raddeanin R3 |
Apoptosis; HDAC | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair |
Raddeanin A (NSC-382873) 是竹节香附中的一种天然三萜皂苷,可抑制组蛋白去乙酰化酶,具有很强的抗血管生成能力和抗肿瘤活性。 | |||
T5797 |
Raddeanoside R8
多被银莲花皂苷R8 |
Others | Others |
Raddeanoside R8 是一种分离自多被银莲花新鲜的根茎中的皂苷。 | |||
TN7021 |
Ent-toddalolactone
|
Others | Others |
Ent-toddalolactone 是一种天然化合物,属于香豆素类,来源于两面针,具有抗炎、抗癌活性。 | |||
T3S0601 |
Buddlejasaponin IVb
醉鱼草皂苷IVb,Saikosaponin 1b |
Others | Others |
Buddlejasaponin IVb (Saikosaponin 1b) 是一种三萜皂苷,从Clinopodium chinense (Benth.) O. Kuntze 中分离得到,能够缩短凝血时间,具有止血作用。 | |||
T4S0592 |
Toddalolactone
(+)-Toddalolactone,飞龙掌血内酯,毛两面针素 |
PAI-1 | Metabolism |
Toddalolactone ((+)-Toddalolactone) 是一种Toddalia asiatica 的主要成分,能够抑制重组人纤溶酶原激活物抑制物-1(PAI-1)的活性, IC50=37.31 μM。 | |||
TN5894 |
Toddanol
(-)-Toddanol,(-)-飞龙掌血烯醇内酯 |
Others | Others |
Toddanol ((-)-Toddanol) 是一种从 Toddalia 根中提取的香豆素。 | |||
TN5888 |
Toddaculin
|
Others | Others |
Toddaculin 是一种天然香豆素,抑制过度的破骨细胞活性并增强成骨细胞分化和矿化。它可诱导白血病细胞分化和凋亡,具有抗炎活性。 | |||
TN5150 |
Toddalosin
|
Others | Others |
Toddalosin是一种天然产物,属于芸香科飞龙掌血属,其产品编号为 TN5150,CAS号为 137182-37-7。Toddalosin可用作对照参考。 | |||
TN5889 |
(-)-Toddalolactone 3′-O-β-D-glucopyranoside
|
||
(-)-Toddalolactone 3′-O-β-D-glucopyranoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5889,CAS号为 1176645-57-0。 | |||
TN4863 |
Raddeanoside R17
Pulchinenoside E3,白头翁皂苷E3 |
Others | Others |
Raddeanoside R17 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4863,CAS号为 824401-07-2。 | |||
T80969 |
Toddanone
|
||
Toddanone是从积雪草(Toddalia asiatica)的根部分离出的香豆素类化合物。 | |||
T75486 |
Toddacoumalone
|
||
Toddacoumalone 是一种天然PDE4 (磷酸二酯酶 4) 抑制剂,效力中等,活性分子特性不完善。具有研究银屑病等炎症性疾病潜力。 | |||
TN5895 |
Toddalosin ethyl ether
|
||
Toddalosin ethyl ether 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5895,CAS号为 1538607-31-6。 | |||
TN5893 |
Toddalolactone 3′-O-ethyl ether
|
||
Toddalolactone 3′-O-ethyl ether 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5893,CAS号为 1538607-30-5。 | |||
T81315 |
Raddeanoside R16
|
||
Raddeanoside R16,一种齐墩果烷型皂苷,可从Anemone raddeana根茎中分离。 | |||
TN1458 |
Buddlejasaponin IV
|
PARP; Akt; Chk | Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling |
Buddlejasaponin IV has analgesic and anti-inflammatory effects, the inhibitions of the expressions of iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 by blocking NF-kappaB activation. | |||
TN4913 |
Riddelline
|
VEGFR; DNA/RNA Synthesis | Angiogenesis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Tyrosine Kinase/Adaptors |
Riddelline is a potent genotoxic agent in vitro and induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver. | |||
TN2134 | Raddeanoside 20 | Others | Others |
Raddeanoside 20 can slightly suppress the superoxide generation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP) in a concentration dependent manner. | |||
TN3545 | Buddlenoid A | Tyrosinase | Proteases/Proteasome |
Buddlenoid A shows high inhibition of mushroom tyrosinase. | |||
TN5896 |
Toddalolactone 3′-O-methyl ether
|
||
Toddalolactone 3′-O-methyl ether 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5896,CAS号为 143614-35-1。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03497 |
AKR1C2 Protein, Human, Recombinant (His)
AKR1C2,HBAB,SRXY8,AKR1C-pseudo,aldo-keto reductase family 1,... |
Human | E. coli |
AKR1C2 is a member of the aldo/keto reductase superfamily, which consists of more than 4 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. AKR1C2 gene shares high sequence identity with three other gene ... | |||
TMPJ-00207 |
AKR1C2 Protein, Human, Recombinant
3-Alpha-HSD3,Chlordecone Reductase Homolog HAKRD,2-Diol Dehy... |
Human | E. coli |
Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol). | |||
TMPY-00481 |
AKR1C4 Protein, Human, Recombinant (His)
aldo-keto reductase family 1, member C4,3-alpha-HSD,DD |
Human | E. coli |
Aldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. there is a strong correlation between the expression levels of these family members and the malignant transformation as well as the resistance to cancer therapy. Type I human hepatic 3alpha-hydroxysteroid dehydrogenase (AKR1C4) plays a significant role in bile acid biosynthesis, steroid hormone metabolism, an... | |||
TMPY-02461 |
AKR1A1 Protein, Human, Recombinant (His)
DD3,ALDR1,HEL-S-6,aldo-keto reductase family 1, mem... |
Human | E. coli |
Aldehyde reductase (AKR1A1) is a member of the aldo-keto reductase superfamily, which consists of more than 40 known enzymes and proteins that includes variety of monomeric NADPH-dependent oxidoreductases, such as aldehyde reductase. Aldehyde reductase has wide substrate specificities for carbonyl compounds. These enzymes are implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Aldehyde reductase possess a structure with a beta-alpha-beta fo... | |||
TMPY-01289 |
DDR1 Protein, Human, Recombinant (His)
RTK6,DDR,TRKE,PTK3,NTRK4,NEP,PTK3A,MCK10,EDD |
Human | HEK293 Cells |
DDR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is A0A024RCQ1. | |||
TMPY-00981 |
ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480,DDDDK)
CD54,ICAM-1,intercellular adhesion molecule 1,P3.58,BB2 |
Human | HEK293 Cells |
ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480,DDDDK) is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.2 kDa and the accession number is A0A384MEK5. | |||
TMPY-02213 |
RAIDD Protein, Human, Recombinant (His)
RAIDD,MRT34,CASP2 and RIPK1 domain containing adapt... |
Human | E. coli |
Death domain-containing protein CRADD, also known as Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CRADD and RAIDD, is a protein which is constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney. CRADD / RAIDD contains oneCARD domain and onedeath domain. CRADD / RAIDD contains a death domain involved in the binding of RIP protein. The CARD domain mediates the ... | |||
TMPY-02050 |
DDOST Protein, Human, Recombinant
CDG1R,OST48,OKSWcl45,AGER1,OST,dolichyl-diphosphooligosaccha... |
Human | E. coli |
The enzyme oligosaccharyltransferase (dolichyl-diphosphooligosaccharide-protein glycosyltransferase) (DDOST), or 48-kDa subunit (OST48) is one of the catalytic subunits in this complex, exerts a typical type I membrane topology, containing a large luminal domain, a hydrophobic transmembrane domain and a short cytosolic peptide tail. DDOST/OST48 catalyzes the transfer of a high-mannose oligosaccharide (GlcNac2Man9Glc3) from a dolichol-linked oligosaccharide donor (dolichol-P-GlcNac2Man9Glc3) onto... | |||
TMPH-00578 |
NrdD Protein, E. coli, Recombinant (His)
|
E. coli | E. coli |
Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair. NrdD Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 84.0 kDa and the accession number is P28903. | |||
TMPY-03352 |
Influenza A H7N2 (A/ruddy turnstone/New Jersey/563/2006) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H7N2 | Baculovirus Insect Cells |
Influenza A H7N2 (A/ruddy turnstone/New Jersey/563/2006) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is C6KLK6. | |||
TMPY-03313 |
DDR1 Protein, Rat, Recombinant (His)
discoidin domain receptor tyrosine kinase 1,Drd1,PTK3D,Cak |
Rat | HEK293 Cells |
DDR1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.3 kDa and the accession number is Q6MG19. | |||
TMPH-01206 |
DDTL Protein, Human, Recombinant (His & Myc)
D-dopachrome tautomerase-like protein,DDTL,D-dopach... |
Human | E. coli |
May have lyase activity. | |||
TMPY-03593 |
DDR2 Protein, Rhesus, Recombinant (His)
discoidin domain receptor tyrosine kinase 2 |
Rhesus | HEK293 Cells |
DDR2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.1 kDa and the accession number is XP_001118219.1. | |||
TMPY-04361 |
DDR2 Protein, Human, Recombinant (aa 422-855, His & GST)
discoidin domain receptor tyrosine kinase 2,NTRKR3,CD167,TYR... |
Human | Baculovirus Insect Cells |
DDR2 Protein, Human, Recombinant (aa 422-855, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 77.1 kDa and the accession number is Q16832. | |||
TMPK-00311 |
APCDD1 Protein, Human, Recombinant (His)
HHS,B7323,Apcdd1,Drapc1,HYPT1,HTS,FP7019 |
Human | HEK293 Cells |
APCDD1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 54.4 kDa and the accession number is Q8J025. | |||
TMPK-00864 |
DDT Protein, Human, Recombinant (His)
Phenylpyruvate tautomerase II,D-dopachrome tautomerase,D-DT,... |
Human | E. coli |
D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT protein also is present in most tissues and circulates in serum at similar concentrations as MIF. D-DT binds the MIF cell surface receptor complex, CD74/CD44, with high affinity and induces similar cell signaling and effector functions. DDT Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predict... | |||
TMPH-02996 |
KsdD Protein, Mycobacterium smegmatis, Recombinant (His & Myc)
|
Mycolicibacterium smegmatis | E. coli |
Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids. Is also involved in the formation of 1,4-androstadiene-3,17-dione (ADD) from 4-androstene-3,17-dione (AD) to. KsdD Protein, Mycobacterium smegmatis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 68.9 kDa and the accession number is A0R4S9. | |||
TMPH-01900 |
DDX5 Protein, Human, Recombinant (His & Myc)
HELR,RNA helicase p68,HLR1,G17P1,DEAD box protein 5,Probable... |
Human | E. coli |
DDX5 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 74.1 kDa and the accession number is P17844. | |||
TMPY-03625 |
DDR2 Protein, Human, Recombinant (His)
MIG20a,CD167,discoidin domain receptor tyrosine kinase 2,TKT... |
Human | HEK293 Cells |
DDR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.1 kDa and the accession number is Q16832. | |||
TMPY-04442 |
DDR1 Protein, Mouse, Recombinant (His & GST)
6030432F18,Nep,Cak,AI323681,CD167a,discoidin domain receptor... |
Mouse | Baculovirus Insect Cells |
DDR1 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.8kDa and the accession number is Q03146-2. | |||
TMPJ-01133 |
NEDD8 Protein, Human, Recombinant (His & SUMO)
Neddylin,Ubiquitin-like protein Nedd8,NE |
Human | E. coli |
Human NEDD8 shares 60% amino acid sequence identity to ubiquitin. The only known substrates of NEDD8 modification are the cullin subunits of SCF ubiquitin E3 ligases. The NEDDylation of cullins is critical for the recruitment of E2 to the ligase complex, thus facilitating ubiquitin conjugation. NEDD8 modification has therefore been implicated in cell cycle progression and cytoskeletal regulation. NEDD8 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHi... | |||
TMPY-03098 |
DDR2 Protein, Rat, Recombinant (hFc)
discoidin domain receptor tyrosine kinase 2 |
Rat | HEK293 Cells |
DDR2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69.5 kDa and the accession number is B1WC09. | |||
TMPY-03655 |
GADD45G Protein, Human, Recombinant
GADD45γ,growth arrest and DNA-damage-inducible, γ,<... |
Human | E. coli |
GADD45G, also known as CR6, is part of the nuclear proteins to interact with various proteins whose transcript levels are raised after stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G reacts to environmental stresses by mediating activation of the p38/JNK pathway which is mediated through their protein binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. GADD45G acts as a new-age tumor suppressor however is being fr... | |||
TMPH-01902 |
DDX60 Protein, Human, Recombinant (His)
Probable ATP-dependent RNA helicase DDX60,DEAD box ... |
Human | E. coli |
Positively regulates DDX58/RIG-I- and IFIH1/MDA5-dependent type I interferon and interferon inducible gene expression in response to viral infection. Binds ssRNA, dsRNA and dsDNA and can promote the binding of DDX58/RIG-I to dsRNA. Exhibits antiviral activity against hepatitis C virus and vesicular stomatitis virus (VSV). DDX60 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.1 kDa and the accession number is Q8IY2... | |||
TMPH-01732 |
DDAH1 Protein, Human, Recombinant (His & Myc)
DDAHI,N(G),N(G)-dimethylarginine dimethylaminohydro... |
Human | E. coli |
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. DDAH1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 38.4 kDa and the accession number is O94760. | |||
TMPJ-00711 |
GADD45G Protein, Human, Recombinant (His)
Cytokine-Responsive Protein CR6,Growth Arrest and DNA Damage... |
Human | E. coli |
Growth Arrest and DNA Damage-Inducible Protein GADD45 Υ (GADD45G) is a nuclear protein which belongs to the GADD45 family. GADD45G is highly expressed in placenta. GADD45G interacts with various proteins whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. GADD45G is also involved in the regulation of growth and apo... | |||
TMPH-02133 |
DDX39B Protein, Human, Recombinant (GST)
UAP56,HLA-B-associated transcript 1 protein,DDX39B,... |
Human | E. coli |
Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it fun... | |||
TMPY-02150 |
GADD45A Protein, Human, Recombinant (His & GST)
GADD45,growth arrest and DNA-damage-inducible, alph... |
Human | Baculovirus Insect Cells |
GADD45A is a member of the GADD45 Family, and has been found to associate with several cytoplasmic and nuclear factors and has been implicated in several cellular functions, including MAPK signaling, cell cycle regulation, DNA repair and genomic stability, apoptosis, and immune responses. The GADD45 Family of genes is rapidly induced by different stressors, including differentiation-inducing cytokines, and there is a large body of evidence that their cognate proteins are key players in cellular ... | |||
TMPY-03046 |
APCDD1 Protein, Human, Recombinant (hFc)
HYPT1,B7323,adenomatosis polyposis coli down-regulated 1,HTS... |
Human | HEK293 Cells |
Osteosarcoma (OS) is the most common type of bone tumor in children and adults. The expression of APCDD1, a Wnt antagonist, was reduced in OS tissues and cells compared to adjacent normal tissue and osteoblast cells, respectively. Mechanistically, this was due to increased levels of methylation in the promoter region of the APCDD1 gene. Consistently, the DNA methyltransferase inhibitor 5-AZA-dC, reduced DNA methylation in the APCDD1 promoter, and restored APCDD1 expression in OS tissue and cells... | |||
TMPY-03541 |
DDR1 Protein, Rat, Recombinant (hFc)
Drd1,Cak,discoidin domain receptor tyrosine kinase 1,PTK3D |
Rat | HEK293 Cells |
DDR1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.9 kDa and the accession number is Q6MG19. | |||
TMPH-03533 |
Ddl Protein, S. aureus, Recombinant (His & Myc)
ddl,D-alanylalanine synthetase,D-Ala-D-Ala ligase,D... |
Staphylococcus aureus | E. coli |
Cell wall formation. Ddl Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 47.7 kDa and the accession number is P63891. | |||
TMPH-00979 |
DDX3Y Protein, Human, Recombinant (His & Myc)
DDX3Y,DBY,DEAD box protein 3, Y-chromosomal,ATP-dep... |
Human | Baculovirus Insect Cells |
DDX3Y Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus. | |||
TMPH-00524 |
ATP-dependent DNA helicase dda Protein, Enterobacteria phage T4, Recombinant (His)
ATP-dependent DNA helicase dda,dda,sud |
Enterobacteria phage T4 | E. coli |
DNA helicase that stimulates viral DNA replication and recombination. Plays a role in T4 DNA replication initiation by selecting and activating DNA origins. Acts by dissociating and reassociating with the DNA molecule being unwound. Unwinds DNA as a monomer in a 5'-to-3' direction at a rate of 250 bp/s and can efficiently displace proteins from the DNA. ATP-dependent DNA helicase dda Protein, Enterobacteria phage T4, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. T... | |||
TMPJ-00907 |
GADD45A Protein, Human, Recombinant (His)
GADD45,DDIT1,Growth Arrest and DNA Damage-... |
Human | E. coli |
Growth Arrest and DNA Damage-Inducible Protein GADD45 α (GADD45A) is a member of the GADD45 family. GADD45A can be induced by UV irradiation, X-rays, growth arrest and alkylating agents, of which can be mediated by some kinases other than PKC. GADD45A can interact with MAPK14, GADD45GIP1, PCNA. In T-cells, GADD45A functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity. GADD45A may affect PCNA interaction with some cell division protein kinase complexes, stimulating ... | |||
TMPH-00975 |
DDX1 Protein, Human, Recombinant (His & Myc)
DBP-RB,DDX1,ATP-dependent RNA helicase DDX... |
Human | E. coli |
DDX1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPY-02506 |
DDR1 Protein, Mouse, Recombinant (hFc)
AI323681,CD167a,Nep,Cak,PTK3A,6030432F18,discoidin domain re... |
Mouse | HEK293 Cells |
DDR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71 kDa and the accession number is Q03146-1. | |||
TMPJ-00700 |
GADD45B Protein, Human, Recombinant (His)
MYD118,Myeloid Differentiation Primary Response Protein MyD1... |
Human | E. coli |
Growth Arrest and DNA Damage-Inducible Protein GADD45 β (GADD45B) is a member of the GADD45 family. GADD45B has been shown to interact with MAP3K4, ASK1, MAP2K7, and GADD45GIP1. GADD45B is involved in the regulation of growth and apoptosis. GADD45B reacts to environmental stresses by mediating activation of stress-responsive MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. In addition, GADD45B participates in the down-regulation of hepatocellular carcinoma (HCC). It m... | |||
TMPY-06039 |
gp130/IL6ST Protein, Human, Recombinant (aa 1-618, DDDDK)
GP130,CD130,interleukin 6 signal transducer,CDW130,IL-6RB |
Human | HEK293 Cells |
gp130/IL6ST Protein, Human, Recombinant (aa 1-618, DDDDK) is expressed in HEK293 mammalian cells. The predicted molecular weight is 68.4 kDa and the accession number is P40189-1. | |||
TMPY-00773 |
DDR2 Protein, Human, Recombinant (hFc)
MIG20a,TYRO10,CD167,NTRKR3,discoidin domain receptor tyrosin... |
Human | HEK293 Cells |
DDR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69.4 kDa and the accession number is Q16832. | |||
TMPH-00976 |
DDX19A Protein, Human, Recombinant (His & SUMO)
DDX19L,DDX19A,DDX19-like protein,... |
Human | E. coli |
DDX19A Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-01901 |
DDX53 Protein, Human, Recombinant (His & Myc)
DEAD box protein CAGE,DEAD box protein 53,CAGE,CT26,Probable... |
Human | E. coli |
N/A. DDX53 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 76.2 kDa and the accession number is Q86TM3. | |||
TMPY-04382 |
DDR1 Protein, Human, Recombinant (aa 444-913, His & GST)
discoidin domain receptor tyrosine kinase 1,NEP,TRKE,DD<... |
Human | Baculovirus Insect Cells |
DDR1 Protein, Human, Recombinant (aa 444-913, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 80 kDa and the accession number is Q08345-1. | |||
TMPH-00978 |
DDX3X Protein, Human, Recombinant (His & Myc)
DEAD box, X isoform,DEAD box protein 3, X-chromosomal,HLP2,<... |
Human | Baculovirus Insect Cells |
DDX3X Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 77 kDa and the accession number is O00571. | |||
TMPY-00422 |
Influenza A H7N2 (A/ruddy turnstone/New Jersey/563/2006) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H7N2 | HEK293 Cells |
Influenza A H7N2 (A/ruddy turnstone/New Jersey/563/2006) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is C6KLK6. | |||
TMPY-01060 |
DOPA Decarboxylase/DDC Protein, Human, Recombinant (His)
dopa decarboxylase (aromatic L-amino acid decarboxylase),AAD... |
Human | Baculovirus Insect Cells |
DOPA Decarboxylase/DDC Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 55 kDa and the accession number is Q53Y41. | |||
TMPK-00989 |
APCDD1 Protein, Mouse, Recombinant (His)
FP7019,HTS,Drapc1,HHS,Apcdd1,B7323,HYPT1 |
Mouse | HEK293 Cells |
APCDD1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 54.4 kDa and the accession number is Q3U128. | |||
TMPY-01728 |
DDR2 Protein, Mouse, Recombinant (His)
AW495251,discoidin domain receptor tyrosine kinase 2,tyro10,... |
Mouse | HEK293 Cells |
DDR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.88 kDa and the accession number is Q62371. | |||
TMPY-02310 |
DDR1 Protein, Mouse, Recombinant (His)
CD167a,discoidin domain receptor tyrosine kinase 1,AI323681,... |
Mouse | HEK293 Cells |
DDR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.4 kDa and the accession number is Q03146-1. | |||
TMPK-00722 |
DDT Protein, Mouse, Recombinant (His)
DDCT,D-dopachrome tautomerase,MIF2,Phenylpyruvate t... |
Mouse | E. coli |
D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT protein also is present in most tissues and circulates in serum at similar concentrations as MIF. D-DT binds the MIF cell surface receptor complex, CD74/CD44, with high affinity and induces similar cell signaling and effector functions. DDT Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predict... | |||
TMPH-03277 |
DDT Protein, Rat, Recombinant (His & Myc)
D-dopachrome decarboxylase,Ddt,D-dopachrome tautome... |
Rat | E. coli |
Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI). DDT Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 20.4 kDa and the accession number is P80254. | |||
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