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244

抑制剂 & 化合物

1000+

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T19936	Xantphos
	Xantphos 是 Buchwald, Suzuki 等偶联反应中的配体，是可用于催化反应的金属螯合配体。
T2006	Omecamtiv mecarbil CK-1827452	ATPase; Myosin	Cytoskeletal Signaling; Membrane transporter/Ion channel
	Omecamtiv mecarbil (CK-1827452) 是一种心脏特异性的肌球蛋白激活剂，用于研究心脏相关疾病。
T2669	Berzosertib VX-970,VE-822	ATM/ATR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	Berzosertib (VE-822) 已用于研究卵巢肿瘤、卵巢浆液性肿瘤、成人实体瘤、晚期实体瘤和晚期实体瘤等治疗的试验。
T8687	diaminohydroxypropanetetraacetic acid	Others	Others
	diaminohydroxypropanetetraacetic acid 已被研究用于治疗血管疾病、冠状动脉疾病、心肌缺血、冠状动脉再狭窄和冠状动脉疾病等。
T3099	Pinometostat EPZ-5676	Histone Methyltransferase	Chromatin/Epigenetic
	Pinometostat (EPZ-5676) 是有效的DOT1L 组蛋白甲基转移酶抑制剂，Ki 为 80 pM。它可用于研究多种白血病治疗的实验。
T7528	3,7-dimethylocta-2,6-dienyl 5,9,13-trimethyltetradeca-4,8,12-enoate	Others	Others
	3,7-dimethylocta-2,6-dienyl 5,9,13-trimethyltetradeca-4,8,12-enoate 是一种有用的研究化合物，适用于许多研究应用，包括化学领域和生命科学领域等。
T2503	PAC-1 Procaspase activating compound 1	Apoptosis; Caspase; Autophagy	Apoptosis; Autophagy; Proteases/Proteasome
	PAC-1 (Procaspase activating compound 1) 是一种 procaspase-3激活剂，诱导癌细胞凋亡，EC50为 2.08 μM，可用于研究淋巴瘤、黑色素瘤、实体瘤、乳腺癌和胸癌等治疗的试验。
T13572	Cancer-Targeting Compound 1	Others	Others
	Cancer-Targeting Compound 1可用于激素相关癌症的研究，包括治疗或预防肌瘤、子宫平滑肌瘤、多囊卵巢综合征或激素依赖性癌等等。
T3049	TPCA-1 GW683965,IKK2 Inhibitor IV,TPCA1	Apoptosis; IκB/IKK; STAT	Apoptosis; JAK/STAT signaling; NF-κB; Stem Cells
	TPCA-1 (TPCA1) 是一种选择性IKK-2抑制剂，IC50值为 17.9 nM。它也是反式激活、DNA 结合以及STAT3磷酸化的一种抑制剂。
T2709	TAK-901 TAK901	JAK; CDK; Src; Aurora Kinase	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	TAK-901是一种多靶点的极光激酶抑制剂，对极光激酶 A 和 B 的 IC50值分别为 21 和 15 nM。它用于研究淋巴瘤、骨髓纤维化、多发性骨髓瘤、骨髓化生和晚期实体瘤等治疗的试验。
T14052	5-IAF 5-Iodoacetamidofluorescein
	5-IAF 是吲哚乙酰胺的一种荧光素衍生物，是一种荧光探针，可用来标记蛋白质和其他含有游离硫醇（半胱氨酸侧链）。5-IAF 可标记狗肾脏Na,K-ATP 酶的催化（α）亚单位。
T9195	SHR0302 ARQ252	Apoptosis; JAK	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	SHR0302 (ARQ252) 是一种具有口服活性的 JAK 抑制剂。它对 JAK1的结合力是 JAK2的 10 倍以上，是 JAK3的 77 倍，是 Tyk2的 420 倍。它抑制JAK1-STAT3磷酸化并诱导肝星状细胞凋亡，具有抗增殖和抗炎作用。
T2365	Pilaralisib SAR245408,XL-147	PI3K	PI3K/Akt/mTOR signaling
	Pilaralisib (XL-147) 是一种有效的、选择性的 I 类PI3Ks 抑制剂，能够抑制 PI3Kα (IC50:39 nM)，PI3Kβ (IC50:383 nM)，PI3Kγ (IC50:23 nM) 和 PI3Kδ (IC50:36 nM)。
T1109	(Z)-Capsaicin Zucapsaicin,Civamide,cis-Capsaicin,珠卡赛辛,(Z)-辣椒素	TRP/TRPV Channel; HSV	Membrane transporter/Ion channel; Microbiology/Virology
	(Z)-Capsaicin (Zucapsaicin) 是天然辣椒素的合成顺式异构体，用于治疗膝骨关节炎。它是一种可口服的 TRPV1激动剂，可研究神经性疼痛。
T0082	Domperidone R33812,多潘立酮	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Domperidone (R33812) 是多巴胺 2 受体拮抗剂，能够影响胃和小肠的化学感受器触发区和运动功能，具有止吐和促动力作用。
T8794	4-MMPB 15-Lipoxygenase Inhibitor 1	Apoptosis; Others; Lipoxygenase	Apoptosis; Metabolism; Others
	4-MMPB (15-Lipoxygenase Inhibitor 1) 是一种选择性15-脂氧合酶抑制剂，其 IC50值为 18 μM，具有前列腺癌的研究潜力。它对大豆 15-脂氧合酶和人 15-脂氧合酶-1 的 IC50 分别为 19.5 μM 和 19.1 μM。
T1916	Apitolisib RG 7422,GNE 390,GDC-0980	Apoptosis; PI3K; mTOR	Apoptosis; PI3K/Akt/mTOR signaling
	Apitolisib (RG 7422) 是一种口服有效的 PI3K 和 mTOR(TORC1/2) 激酶抑制剂，抑制 PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ的活性，IC50值为 5 nM/27 nM/7 nM/14 nM，抑制 mTOR，Ki 为 17 nM。它用于乳腺癌、前列腺癌、肾细胞癌和子宫内膜癌等实体癌的试验研究。
T6883	Samotolisib GTPL8918,LY3023414	DNA-PK; PI3K; mTOR; Autophagy	Autophagy; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	Samotolisib (LY3023414) 在低纳摩尔浓度下，有效抑制mTORC1/2。它选择性地有效抑制PI3Kα、PI3Kβ、PI3Kδ、PI3Kγ、DNA-PK 和mTOR，IC50分别为 6.07 nM、77.6 nM、38 nM、23.8 nM、4.24 nM 和 165 nM。它可用于多种肿瘤和癌症的试验。
T6157	Devimistat CPI-613,辛酸,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid	Apoptosis; Dehydrogenase; Mitochondrial Metabolism	Apoptosis; Metabolism
	Devimistat (6,8-Bis(benzylthio)octanoic acid) 是一种线粒体代谢抑制剂，还是一种lipoic acid 拮抗剂，能阻断线粒体能量代谢，诱导多种癌细胞凋亡。
T0093L	Sorafenib 索拉非尼,Bay 43-9006	Apoptosis; Raf; VEGFR; FLT; Ferroptosis; PDGFR; c-Kit; Autophagy	Angiogenesis; Apoptosis; Autophagy; MAPK; Tyrosine Kinase/Adaptors
	Sorafenib (Bay 43-9006) 是一种多激酶抑制剂，抑制 Raf-1、B-Raf、VEGFR2、VEGFR3、VEGFR4、PDGFRβ、FLT3、c-Kit 等 (IC50=6/22/90/15/20/20/57/58 nM)，具有口服活性。Sorafenib 具有抗肿瘤活性，可以诱导细胞自噬和凋亡，也可以激动铁死亡。
T8839	ICCB280	Apoptosis; Others	Apoptosis; Others
	ICCB280 是一种 C/EBPα诱导剂，通过激活 C/EBPα 并影响其下游靶点，具有终末分化、增殖停滞和凋亡的抗白血病特性。
T6552	Istradefylline 伊曲茶碱,KW-6002	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Istradefylline (KW-6002) 是选择性的可口服的腺苷 A2A 受体拮抗剂，可用于研究药物滥用、睡眠障碍、肝损伤、帕金森病和不安腿综合征等的治疗和基础科学的试验。
T3614	Inosine pranobex Groprinosin,Isoprinosine,异丙肌苷,Immunovir,Delimmun	IL Receptor; HIV Protease	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Inosine pranobex (Delimmun) 是一种免疫增强剂，它是一种广谱抗病毒剂，用于 HIV 感染。
T1220	Ethidium bromide EtBr,Homidium bromide,EB,溴化乙啶	AChR	Neuroscience
	Ethidium bromide (EB) 是一种可用作分子生物实验学中的荧光标记(核酸染色)，如琼脂糖凝胶电泳。Ethidium bromide 的λEx 为300-360 nm,λEm为590 nm。
T6399	AZD1981	GPR; Prostaglandin Receptor	Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation
	AZD1981 是一种有效且特异性的 CRTh2 (DP2) 受体拮抗剂，IC50为 4 nM，用于研究哮喘、绝经后、药代动力学、哮喘患者和药物相互作用等治疗和基础科学的试验。
T8844	Diflapolin	Others; FLAP; Epoxide Hydrolase	Immunology/Inflammation; Metabolism; Others
	Diflapolin 是高活性的双 5-脂氧合酶激活蛋白(FLAP)/可溶性环氧化物水解酶抑制剂，具有显著的抗炎作用和较高的靶向选择性。它抑制分离的 sEH 的活性，IC50为20 nM。它还抑制完整人单核细胞和中性粒细胞中 5-LOX 产物的形成，IC50分别为 30 和 170 nM。
TNU0739	(-)-(1S,5R)-cis-Bicyclo[3.2.0]hept-2-en-6-one
	Building block - others
T40620	Vinleurosine sulfate
	Vinleurosine sulfate, extracted from Vinca rosea Linn, is a potent antineoplastic indole alkaloid along with three others.
TNU0989	Ethyl (R)-2-benzoylpyrrolidine-1-carboxylate
	Intermediates and Building Blocks - Others; Fine Chemicals
TNU0904	N4-(4-Boc-aminobutyl)quinoline-3,4-diamine
	Heterocyclic Compounds - Quinolines; Intermediates and Building Blocks –Others
T38679	DODAP
	DODAP, an ionizable cationic lipid, serves as a vital component in liposome formation. Its applications encompass the capability to encapsulate siRNA, immunostimulatory chemotherapeutic agents for in vitro and in vivo delivery, among others.
TNU0988	Ethyl (S)-2-benzoylpyrrolidine-1-carboxylate
	Intermediates and Building Blocks - Others; Fine Chemicals
TNU0903	N4-(4-Boc-aminobutyl)-3-nitroqunoline-4-amine
	Heterocyclic Compounds - Quinolines; Intermediates and Building Blocks –Others
TNU1478	5-Carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidine acetic acid
	PNA-related Derivatives; Heterocyclic Compounds - Fused polyheterocycles; Intermediates and Building Blocks - Others
T38333	Corynecin I
	Corynecin I is a chloramphenicol-like antibiotic originally isolated from Corynebacterium. It is active against Gram-positive and Gram-negative bacteria with MIC values of 5.2-83 μg/ml for S. sonnei, P. vulgaris, K. pneumoniae, and S. aureus among others.
TNU1474	(1,2-Dihydro-2-oxo-1,8-naphthyridin-3-yl)acetic acid
	PNA-related Derivatives; Heterocyclic Compounds - Fused polyheterocycles; Intermediates and Building Blocks - Others
T68998	Parconazole Free Base
	Parconazole Free Base is used in veterinary as an oral fungicide with a broad-spectrum activity against dermatophytes, yeasts, and others fungi. This compound does not have any antibacterial effect. The mechanism of action involves inhibition of the fungal cytochrome P450 dependent 14alpha-dimethylation of lanosterol to ergosterol.
TNU1473	(1,2-Dihydro-2-oxo-1,8-naphthyridin-3-yl)acetic acid ethyl ester
	PNA-related Derivatives; Heterocyclic Compounds - Fused polyheterocycles; Intermediates and Building Blocks - Others
T69378	Homidium Free Base
	Homidium Free Base is a trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.
T63375	FT709
	FT709 是选择性的USP9X 有效抑制剂 (IC50: 82 nM)。其中USP9X 与中心体功能、EGF 受体降解、有丝分裂期间的染色体排列、化学致敏和昼夜节律有关。
T75066	N1-Methylxylo-guanosine
	N1-Methylxylo-guanosine 为一种具备广泛抗肿瘤活性的嘌呤核苷类似物，主要针对惰性淋巴系统恶性肿瘤。其抗癌机制涉及抑制 DNA 合成与诱导细胞凋亡(apoptosis)。
T75036	N1-(2-Methyl)propyl pseudouridine
	N1-(2-Methyl)propyl pseudouridine 是一种具有广泛抗肿瘤活性的嘌呤核苷类似物，主要用于靶向惰性淋巴系统恶性肿瘤。其抗癌机制包括抑制 DNA 合成和诱导细胞凋亡（apoptosis）。
T40701	Ezeprogind AZP-2006
	Ezeprogind (AZP-2006) is an orally active neurotrophic inducer that effectively addresses the underlying factors contributing to neurodegeneration, with a broad scope extending beyond the conventional targets like Abeta protein and tau protein. Exhibiting potent neuroprotective properties, Ezeprogind is a valuable tool for studying a range of neurological disorders, including progressive supranuclear palsy (PSP), tauopathies, Alzheimer's disease, Parkinson's disease, and others.
T70275	PAT-347
	PAT-347 is a potent Autotaxin Inhibitor. Autotaxin (ATX) is a secreted enzyme responsible for the hydrolysis of lysophosphatidylcholine (LPC) to the bioactive lysophosphatidic acid (LPA) and choline. The ATX-LPA signaling pathway is implicated in cell survival, migration, and proliferation; thus, the inhibition of ATX is a recognized therapeutic target for a number of diseases including fibrotic diseases, cancer, and inflammation, among others.
T75053	3’-β-C-Methyl-2-thiouridine
	3’-β-C-Methyl-2-thiouridine 是一种具有广泛抗肿瘤活性的嘌呤核苷类似物，主要通过抑制DNA合成及诱导细胞凋亡（apoptosis）等机制，靶向惰性淋巴系统恶性肿瘤。
T75062	N6-Methyl-2’-O-(2-methoxyethyl) adenosine
	N6-Methyl-2’-O-(2-methoxyethyl) adenosine 为嘌呤核苷类似物，具备广泛抗肿瘤活性，主要靶向惰性淋巴系统恶性肿瘤。其抗癌机制涉及抑制 DNA 合成及诱导细胞凋亡(apoptosis)。
T75060	N7-Methyl-2’-O-(2-methoxyethyl) guanosine
	N7-Methyl-2’-O-(2-methoxyethyl) guanosine 是一种具有抗肿瘤活性的嘌呤核苷类似物，主要靶向惰性淋巴系统恶性肿瘤。其作用机制包括抑制 DNA 合成和诱导细胞凋亡(apoptosis)。
T75213	TLR7 agonist 12
	TLR7 agonist12 (example 20) 是一种针对惰性淋巴系统恶性肿瘤具有广泛抗肿瘤活性的TLR7激动剂及嘌呤核苷类似物。其抗癌机制主要通过抑制DNA合成和诱导细胞凋亡(apoptosis)来实现。
T75034	N1-Methylsulfonyl pseudouridine
	N1-Methylsulfonyl pseudouridine 是一种具有广泛抗肿瘤活性的嘌呤核苷类似物，主要针对惰性淋巴系统恶性肿瘤。其抗癌机制涉及抑制 DNA 合成和诱导细胞凋亡（apoptosis）。
T75212	Confiden
	Confiden 为一种嘌呤核苷类似物，广泛抗肿瘤活性，针对惰性淋巴系统恶性肿瘤。其抗癌机制通过抑制DNA合成及诱导细胞凋亡(apoptosis)实现。

化合物

Cat.No: T19936

Omecamtiv mecarbil

Cat.No: T2006

Synonym: CK-1827452

Target: ATPase, Myosin

Cat.No: T2669

Synonym: VX-970,VE-822

Target: ATM/ATR

diaminohydroxypropanetetraacetic acid

Cat.No: T8687

Target: Others

Cat.No: T3099

Synonym: EPZ-5676

Target: Histone Methyltransferase

3,7-dimethylocta-2,6-dienyl 5,9,13-trimethyltetradeca-4,8,12-enoate

Cat.No: T7528

Target: Others

Cat.No: T2503

Synonym: Procaspase activating compound 1

Target: Apoptosis, Caspase, Autophagy

Cancer-Targeting Compound 1

Cat.No: T13572

Target: Others

Cat.No: T3049

Synonym: GW683965,IKK2 Inhibitor IV,TPCA1

Target: Apoptosis, IκB/IKK, STAT

Cat.No: T2709

Synonym: TAK901

Target: JAK, CDK, Src, Aurora Kinase

Cat.No: T14052

Synonym: 5-Iodoacetamidofluorescein

Cat.No: T9195

Synonym: ARQ252

Target: Apoptosis, JAK

Cat.No: T2365

Synonym: SAR245408,XL-147

Target: PI3K

Cat.No: T1109

Synonym: Zucapsaicin,Civamide,cis-Capsaicin,珠卡赛辛,(Z)-辣椒素

Target: TRP/TRPV Channel, HSV

Cat.No: T0082

Synonym: R33812,多潘立酮

Target: Dopamine Receptor

Cat.No: T8794

Synonym: 15-Lipoxygenase Inhibitor 1

Target: Apoptosis, Others, Lipoxygenase

Cat.No: T1916

Synonym: RG 7422,GNE 390,GDC-0980

Target: Apoptosis, PI3K, mTOR

Cat.No: T6883

Synonym: GTPL8918,LY3023414

Target: DNA-PK, PI3K, mTOR, Autophagy

Cat.No: T6157

Synonym: CPI-613,辛酸,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid

Target: Apoptosis, Dehydrogenase, Mitochondrial Metabolism

Cat.No: T0093L

Synonym: 索拉非尼,Bay 43-9006

Target: Apoptosis, Raf, VEGFR, FLT, Ferroptosis, PDGFR, c-Kit, Autophagy

Cat.No: T8839

Target: Apoptosis, Others

Cat.No: T6552

Synonym: 伊曲茶碱,KW-6002

Target: Adenosine Receptor

Inosine pranobex

Cat.No: T3614

Synonym: Groprinosin,Isoprinosine,异丙肌苷,Immunovir,Delimmun

Target: IL Receptor, HIV Protease

Ethidium bromide

Cat.No: T1220

Synonym: EtBr,Homidium bromide,EB,溴化乙啶

Target: AChR

Cat.No: T6399

Target: GPR, Prostaglandin Receptor

Cat.No: T8844

Target: Others, FLAP, Epoxide Hydrolase

(-)-(1S,5R)-cis-Bicyclo[3.2.0]hept-2-en-6-one

Cat.No: TNU0739

Vinleurosine sulfate

Cat.No: T40620

Ethyl (R)-2-benzoylpyrrolidine-1-carboxylate

Cat.No: TNU0989

N4-(4-Boc-aminobutyl)quinoline-3,4-diamine

Cat.No: TNU0904

Cat.No: T38679

Ethyl (S)-2-benzoylpyrrolidine-1-carboxylate

Cat.No: TNU0988

N4-(4-Boc-aminobutyl)-3-nitroqunoline-4-amine

Cat.No: TNU0903

5-Carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidine acetic acid

Cat.No: TNU1478

Cat.No: T38333

(1,2-Dihydro-2-oxo-1,8-naphthyridin-3-yl)acetic acid

Cat.No: TNU1474

Parconazole Free Base

Cat.No: T68998

(1,2-Dihydro-2-oxo-1,8-naphthyridin-3-yl)acetic acid ethyl ester

Cat.No: TNU1473

Homidium Free Base

Cat.No: T69378

Cat.No: T63375

N1-Methylxylo-guanosine

Cat.No: T75066

N1-(2-Methyl)propyl pseudouridine

Cat.No: T75036

Cat.No: T40701

Synonym: AZP-2006

Cat.No: T70275

3’-β-C-Methyl-2-thiouridine

Cat.No: T75053

N6-Methyl-2’-O-(2-methoxyethyl) adenosine

Cat.No: T75062

N7-Methyl-2’-O-(2-methoxyethyl) guanosine

Cat.No: T75060

TLR7 agonist 12

Cat.No: T75213

N1-Methylsulfonyl pseudouridine

Cat.No: T75034

Cat.No: T75212

Cat. No.	Product Name	Target	Signaling Pathways
T3365	Rebaudioside C Dulcoside B,杜尔可苷B	Others; Endogenous Metabolite	Metabolism; Others
	Rebaudioside C (Dulcoside B) 是一种天然甜味剂，能够用于糖尿病患者的控制性饮食。
TN7029	(2S)-1-O-p-coumaroyl-2-O-acetyl-3-O-β-D-glucopyranosylglycerol	Others	Others
	(2S)-1-O-p-coumaroyl-2-O-acetyl-3-O-β-D-glucopyranosylglycerol 是一种有用的研究化合物，适用于许多研究应用，包括化学领域和生命科学领域等。
T2957	Arctigenin 牛蒡苷元,牛蒡子苷元,(-)-Arctigenin	Apoptosis; MMP; Influenza Virus; Autophagy	Apoptosis; Autophagy; Microbiology/Virology; Proteases/Proteasome
	Arctigenin ((-)-Arctigenin) 是一种存在于牛蒡中的木脂素，具有抗氧化、抗肿瘤、抗炎和抗病毒活性。它可研究代谢紊乱和中枢神经系统功能障碍。
T1660	Silibinin 水飞蓟宾 A,水飞蓟宾,Silibinin A,Silybin,Silymarin I	Reactive Oxygen Species; Autophagy	Autophagy; Immunology/Inflammation; Metabolism; NF-κB
	Silibinin (Silybin) 是水飞蓟的主要活性成分，具有抗癌和化疗预防作用，能抑制细胞增殖和迁移。
T8098	γ-Hexalactone γ-caprolactone,gamma-己内酯,γ-己内酯	Others	Others
	γ-Hexalactone (γ-caprolactone) 是一种存在成熟水果中的 gamma 内酯。它会导致 DNA 损伤，可用作对氧磷酶 1 的底物 (PON1)。
T4825	D-(+)-Xylose D(+)-Xylose,木糖,(+)-Xylose,Wood sugar	Endogenous Metabolite	Metabolism
	D-(+)-Xylose (Wood sugar) 是一种是一种戊醛糖，其化学式为C5H10O5，甜度为蔗糖的40%。木糖也存在于结缔组织的粘多糖中，有时也存在于尿液中。
TN3907	Pinosylvin monomethyl ether (E)-3-Hydroxy-5-methoxystilbene	Antifection	Microbiology/Virology
	(E)-3-Hydroxy-5-methoxystilbene possesses inhibitory activity against several Gram-positive bacteria, including isolates of methicillin-resistant Staphylococcus aureus (MRSA), Mycobacterium bovis BCG, and avirulent Bacillusanthracis (Sterne strain), among
T38097	Antibiotic PF 1052
	Antibiotic PF 1052 is a fungal metabolite originally isolated from Phoma.1,2 It is active against S. aureus, S. parvulus, and C. perfringens (MICs = 3.13, 0.78, and 0.39 μg/ml, respectively), among others.1 It inhibits neutrophil migration in a wound assay using zebrafish larvae expressing GFP-labeled neutrophils, reducing pseudopodia formation and inducing rounding of neutrophils.2 Antibiotic PF 1052 is selective for neutrophil migration over macrophage migration in zebrafish larvae. It also in...
T83863	Fluostatin A sodium
	Fluostatin A是一种最初从链霉菌中分离出的荧光酮类化合物。它对二肽基肽酶3（DPP-3）的选择性抑制作用优于对DPP-1、DPP-2和DPP-4的抑制作用（IC50s分别为0.44, >100, >100, 和 >100 µg/ml）。
T70495	Scytonemin
	Scytonemin is a biological pigment synthesized by many strains of cyanobacteria, including Calothrix sp., Lyngbya aestuarii, and others. Scytonemin is also a potent PKL1 inhibitor, which inhibits cell proliferation and arrests cell cycle through downregulating Plk1 activity in many cancel cells. Scytonemin was able to inhibit the proliferation of three myeloma cells in a dose-dependent manner, while U266 was the most sensitive one to scytonemin. Scytonemin , representing a novel Plk1 inhibitor, ...
T35577	Phosphatidylserines (bovine)
	Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on the inner leaflet of the cell membrane. It is biosynthesized from phosphatidylcholine or phosphatidylethanolamine by phosphatidyl synthase 1 (PSS1) or PSS2, respectively, in the endoplasmic reticulum and can be reversibly converted back by the same enzymes. It can also be irreversi...
T20884	Hydroxyzine Hydroxyzine free base,羟嗪	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Hydroxyzine (Hydroxyzine free base) 是一种组胺 H1 受体拮抗剂，可有效治疗慢性荨麻疹、皮炎和组胺介导的瘙痒。它可作为止吐剂和镇静剂，缓解焦虑和紧张。
TN6832	Sulcatone 6-甲基-5-庚烯-2-酮,6-methylhept-5-en-2-one,6-Methyl-5-hepten-2-one	Endogenous Metabolite	Metabolism
	Sulcatone (6-Methyl-5-hepten-2-one) 是内源性代谢产物的一种。
T19237	Cholesteryl oleate 胆固醇油酸酯,Oleoylcholesterol,Cholesterol Oleate,Cholesteryl cis-9-octadecenoate	Endogenous Metabolite	Metabolism
	Cholesteryl oleate (Cholesteryl cis-9-octadecenoate) 是胆固醇的酯化形式，可用于合成固体脂质纳米颗粒。
TQ0193	N2,N2-Dimethylguanosine N2,N2-二甲基鸟苷	Endogenous Metabolite	Metabolism
	N2,N2-Dimethylguanosine 是尿核苷，是 tRNA 的初级代谢产物。
T8273	4,6-Dioxoheptanoic acid Succinylacetone,4,6-二氧代庚酸	Others; Endogenous Metabolite	Metabolism; Others
	4,6-Dioxoheptanoic acid (Succinylacetone) 是血红素生物合成的有效抑制剂。
T7595	L-DABA L-2,4-Diaminobutyric acid,L-2,4-二氨基丁酸氢溴酸盐,L-DAB HBR	GABA Receptor; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism; Neuroscience
	L-DABA (L-2,4-Diaminobutyric acid) 是GABA 转氨酶的弱抑制剂，IC50值大于500 μM，具有抗肿瘤活性。
TN3748	D-Asparagine D-天冬酰胺,H-D-Asn-OH	Others; Endogenous Metabolite	Metabolism; Others
	D-Asparagine (H-D-Asn-OH) 是酵母菌株的氮源。 D-Asparagine 是 L-Asparagine 水解的竞争性抑制剂 (Ki = 0.24 mM)。
TN6822	3,5-Dimethoxytoluene Orcinol dimethyl ether,1,3-dimethoxy-5-methylbenzene	Others	Others
	3,5-Dimethoxytoluene (Orcinol dimethyl ether) 是玫瑰中主要香味成分，具有镇静作用，可作为一种害虫引诱剂使用。
TN7244	Egg PG Phosphatidylglycerols(egg)
	Egg PG(Phosphatidylglycerols(egg)) 是一种食物和生物组织的主要磷脂酰甘油之一，常存在于细菌和动物细胞的膜中，可作为 sPMCA，反应中的阴离子磷脂底物。
TN6902	Cholesteryl formate 3beta-Acetoxy-cholest-5-ene
	Cholesteryl formate (3beta-Acetoxy-cholest-5-ene) 是首次从红藻中分理出的化合物，是一种胆固醇酯。
TN2206	Shancigusin I 4-(葡糖糖氧基)-肉桂酸葡萄糖氧基苄酯	Others	Others
	Shancigusin I 是来自 Cremastra appendiculata 块茎的天然产物。
TN1658	Ganoderenic acid D	Apoptosis; Others	Apoptosis; Others
	Ganoderenic acid D 是从灵芝提取物 (GLE) 的有效化合物中分离出来的天然产物。 Ganoderenic acid D 诱导细胞周期停滞和细胞凋亡并抑制癌细胞的增殖。
T8020	Benzoyleneurea 亚苯甲酰基脲,2,4-喹唑啉二酮	Antibacterial	Microbiology/Virology
	Benzoyleneurea 拥有抗菌活性，常被用作合成新型 PGGTase-I 的抑制剂。
TN7050	Potassium 7-hydroxy-1-naphthalenesulfona 藏红花酸,2-Naphthol-8-sulfonic Acid Potassium Salt	Others	Others
	Potassium 7-hydroxy-1-naphthalenesulfona (2-Naphthol-8-sulfonic Acid Potassium Salt) 天然存在于茜草科栀子花的果实、鸢尾科番红花的花和玄参科玄参科的花叶中。
T12016	Methyl L-pyroglutamate L-Pyroglutamic acid methyl ester,L-焦谷氨酸甲酯,(S)-Methyl 5-oxopyrrolidine-2-carboxylate	Others	Others
	Methyl L-pyroglutamate (L-Pyroglutamic acid methyl ester) 分离自甘蓝中分离，显示出抗炎活性。
TN2117	Pulsatilloside E 3-O-B-D-葡萄糖( 1→4)-[ A -L-鼠李糖(1→2)]- A-L-阿拉伯糖 23-羟基羽扇豆20(29)-烯-28–酸- 28-O-鼠李糖(1→4)葡萄糖(1→6)葡萄糖苷,Pulchinenoside E,白头翁皂苷E	Others	Others
	Pulsatilloside E (Pulchinenoside E) 是一种从毛茛科白头翁Pulsatilla chinensis (Ranunculaceae)的根中分离出来的天然产物。
TN6864	Prosaikogenin F (2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol,前柴胡皂苷F	Others	Others
	Prosaikogenin F ((2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol) 是一种单糖苷，具有溶血和抗癌特性。
T13515	5-Methoxytryptophol 2-(5-Methoxy-1H-indol-3-yl)ethanol,Methoxytryptophol,5-甲氧基色醇	Endogenous Metabolite	Metabolism
	5-Methoxytryptophol (2-(5-Methoxy-1H-indol-3-yl)ethanol) 是衍生自血清素的松果体吲哚胺，在许多物种中都具有生物特性。
TN7069	2',4,4',6'-Tetramethoxychalcone 2',4,4',6'-TETRAMETHOXY	Others	Others
	2',4,4',6'-Tetramethoxychalcone (2',4,4',6'-TETRAMETHOXY) 是一种天然产物。
T21499	Dimebolin Latrepirdine,Dimebon,Dimebone	5-HT Receptor	GPCR/G Protein; Neuroscience
	Dimebolin (Latrepirdine) 是一种 5-HT6 拮抗剂。
TN6710	Methyl acetylsalicylate ACETYLSALICYLIC ACID METHYL ESTER,乙酰水杨酸甲酯	Others	Others
	Methyl acetylsalicylate (ACETYLSALICYLIC ACID METHYL ESTER) 是一种从豌豆中分离出来的天然产物。抑制胶原蛋白诱导的人富含血小板的血浆聚集。
T8137	(Z)-Aconitic acid 顺乌头酸,顺式乌头酸,Cls-Aconitic acid	Others; Endogenous Metabolite	Metabolism; Others
	(Z)-Aconitic acid 是 Aconitic acid 的顺式异构体。它是三羧酸循环中柠檬酸盐异构化为异柠檬酸盐的中间产物。
T5940	Proxyphylline 羟丙茶碱,7-(2-Hydroxypropyl)theophylline	PDE; Adenosine Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Proxyphylline (7-(2-Hydroxypropyl)theophylline) 是甲基黄嘌呤衍生物，可用作心脏活化剂、血管扩张剂和支气管扩张剂。
T8266	(R)-Citronellol D-Citronellol,(R)-(+)-β-Citronellol,(R)-3,7-二甲基-6-辛烯醇	Others; Endogenous Metabolite	Metabolism; Others
	(R)-Citronellol ((R)-(+)-β-Citronellol) 是一种存在于天竺葵精油中的醇单萜。它抑制肥大细胞的脱颗粒，并且不影响咖啡因的苦味感。它能够用于装饰性化妆品，盥洗用品以及非化妆品中。
TN1539	Cussosaponin C	Others	Others
	Cussosaponin C 是从 Pulsatilla koreana Nakai 中分离得到的天然产物。
TN2119	Pulsatilla saponin H 白头翁属皂苷H,白头翁皂苷 H,3-O-Β-D-葡萄糖( 1→4)-[ A -L-鼠李糖(1→2)]- A-L-阿拉伯糖常春藤配基- 28-O-鼠李糖(1→4)葡萄糖(1→6)葡萄糖苷	Others	Others
	Pulsatilla saponin H 是一种从 Pulsatilla koreana 的根中分离出来的天然产物。
T7335	2,3-Diaminopropionic acid L-2,3-二氨基丙酸,L-2,3-Diaminopropionic acid	Endogenous Metabolite	Metabolism
	2,3-Diaminopropionic acid (L-2,3-Diaminopropionic acid) 是一种神经毒性氨基酸 b-oxalyl-L-a, b-diaminopropionic acid 的代谢产物。
T8088	Furfuryl acetate 乙酸糠醇酯,乙酸糠酯	Others	Others
	Furfuryl acetate 可用于合成 5-乙酰氧基甲基-2-呋喃和 5-羟甲基-2-呋喃。
T20312	3-Phenylpropanal NSC-9271,Phenylpropyl aldehyde,NSC9271,NSC 9271	Others	Others
	3-Phenylpropanal (Phenylpropyl aldehyde) 是RIFM 香料成分，可用于制作香水。3-Phenylpropanal 是杀螨剂的主要成分。3-Phenylpropanal 可作为苍蝇引诱剂使用。
T15254	Ethyl acetoacetate Ethyl acetylacetate	Others; Antibacterial	Microbiology/Virology; Others
	Ethyl acetoacetate (Ethyl acetylacetate) 是一种细菌生物膜抑制剂。Ethyl acetoacetate 是一种酯类，是一种可用于多种化合物合成的中间体。
T15544	Iberin NSC 321801	Endogenous Metabolite	Metabolism
	Iberin (NSC-321801) 诱导细胞凋亡并抑制细胞存活 (IC50 = 2.3 μM)。 Iberin 是萝卜硫素的类似物。
T5246	Trans-2-butene-1,4-dicarboxylic acid trans-2-Butene-1,4-dicarboxylic Acid,3-Hexenedioic Acid,trans-3-Hexenedioic Acid,β-Hydromuconic Acid,反式-2-丁烯-1,4-二甲酸	Others; Endogenous Metabolite	Metabolism; Others
	Trans-2-butene-1,4-dicarboxylic acid (3-Hexenedioic Acid) 是内源性代谢产物的一种。
T8094	16-Dehydroprogesterone 16-Dehydroprogesterone,16-去氢黄体酮	Endogenous Metabolite	Metabolism
	16-Dehydroprogesterone 是甾体孕激素。
T21205	Ponasterone A 坡那甾酮A,AI3-44686	Others	Others
	Ponasterone A (AI3-44686) 是一种蜕皮激素，能够高度亲和蜕皮激素受体。它能够使报告基因能够快速打开和关闭，是细胞和转基因动物中基因表达的有效调节剂。
T64980	ATP disodium trihydrate Adenosine-5'-triphosphate disodium trihydrate	Endogenous Metabolite	Metabolism
	ATP disodium trihydrate (Adenosine-5'-triphosphate disodium trihydrate) 是体内能量储存和代谢的重要物质，是免疫和炎症中重要的内源性信号分子，可为机体代谢提供能量，同时在细胞中作为辅酶发挥作用。
T13655	DL-Norepinephrine hydrochloride 去甲肾上腺素盐酸盐,Lys,DL-lysine	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	DL-Norepinephrine hydrochloride (DL-lysine) 是一种靶向α1 adrenoceptor 和β1 adrenoceptor 的神经递质，可降低心内膜下氧分压。它是一种模拟内源性去甲肾上腺素的拟交感神经作用的合成苯乙胺。
T14853	Cabergoline FCE-21336,卡麦角林	Dopamine Receptor; 5-HT Receptor; Autophagy	Autophagy; GPCR/G Protein; Neuroscience
	Cabergoline (FCE-21336) 是一种麦角衍生的多巴胺 D2亚类受体激动剂，高亲和力作用于D2、D3和5-HT2B 受体，Ki 分别为 0.7、1.5 和 1.2。
T21383	D-Thyroxine Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine	Others	Others
	D-Thyroxine (Dextroxin) 是一种甲状腺激素，对 TSH 的分泌具有抑制作用，可用于研究高胆固醇血症。
T37526	2-Oleoylglycerol 2-Oleoyl Glycerol,2-OG,2-Monoolein	GPR	Endocrinology/Hormones; GPCR/G Protein
	2-Oleoylglycerol 是一种存在于棕榈仁、葵花籽和米糠中的脂质。2-Oleoylglycerol 可当作一种 GPR119 激动剂，具有神经保护作用，可诱导胰高血糖素样肽 1 (GLP-1) 分泌。2-Oleoylglycerol 可用于非酒精性脂肪性肝炎造模。
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天然产物

Cat.No: T3365

Synonym: Dulcoside B,杜尔可苷B

Target: Others, Endogenous Metabolite

(2S)-1-O-p-coumaroyl-2-O-acetyl-3-O-β-D-glucopyranosylglycerol

Cat.No: TN7029

Target: Others

Cat.No: T2957

Synonym: 牛蒡苷元,牛蒡子苷元,(-)-Arctigenin

Target: Apoptosis, MMP, Influenza Virus, Autophagy

Cat.No: T1660

Synonym: 水飞蓟宾 A,水飞蓟宾,Silibinin A,Silybin,Silymarin I

Target: Reactive Oxygen Species, Autophagy

Cat.No: T8098

Synonym: γ-caprolactone,gamma-己内酯,γ-己内酯

Target: Others

Cat.No: T4825

Synonym: D(+)-Xylose,木糖,(+)-Xylose,Wood sugar

Target: Endogenous Metabolite

Pinosylvin monomethyl ether

Cat.No: TN3907

Synonym: (E)-3-Hydroxy-5-methoxystilbene

Target: Antifection

Antibiotic PF 1052

Cat.No: T38097

Fluostatin A sodium

Cat.No: T83863

Cat.No: T70495

Phosphatidylserines (bovine)

Cat.No: T35577

Cat.No: T20884

Synonym: Hydroxyzine free base,羟嗪

Target: Histamine Receptor

Cat.No: TN6832

Synonym: 6-甲基-5-庚烯-2-酮,6-methylhept-5-en-2-one,6-Methyl-5-hepten-2-one

Target: Endogenous Metabolite

Cholesteryl oleate

Cat.No: T19237

Synonym: 胆固醇油酸酯,Oleoylcholesterol,Cholesterol Oleate,Cholesteryl cis-9-octadecenoate

Target: Endogenous Metabolite

N2,N2-Dimethylguanosine

Cat.No: TQ0193

Synonym: N2,N2-二甲基鸟苷

Target: Endogenous Metabolite

4,6-Dioxoheptanoic acid

Cat.No: T8273

Synonym: Succinylacetone,4,6-二氧代庚酸

Target: Others, Endogenous Metabolite

Cat.No: T7595

Synonym: L-2,4-Diaminobutyric acid,L-2,4-二氨基丁酸氢溴酸盐,L-DAB HBR

Target: GABA Receptor, Endogenous Metabolite

Cat.No: TN3748

Synonym: D-天冬酰胺,H-D-Asn-OH

Target: Others, Endogenous Metabolite

3,5-Dimethoxytoluene

Cat.No: TN6822

Synonym: Orcinol dimethyl ether,1,3-dimethoxy-5-methylbenzene

Target: Others

Cat.No: TN7244

Synonym: Phosphatidylglycerols(egg)

Cholesteryl formate

Cat.No: TN6902

Synonym: 3beta-Acetoxy-cholest-5-ene

Cat.No: TN2206

Synonym: 4-(葡糖糖氧基)-肉桂酸葡萄糖氧基苄酯

Target: Others

Ganoderenic acid D

Cat.No: TN1658

Target: Apoptosis, Others

Cat.No: T8020

Synonym: 亚苯甲酰基脲,2,4-喹唑啉二酮

Target: Antibacterial

Potassium 7-hydroxy-1-naphthalenesulfona

Cat.No: TN7050

Synonym: 藏红花酸,2-Naphthol-8-sulfonic Acid Potassium Salt

Target: Others

Methyl L-pyroglutamate

Cat.No: T12016

Synonym: L-Pyroglutamic acid methyl ester,L-焦谷氨酸甲酯,(S)-Methyl 5-oxopyrrolidine-2-carboxylate

Target: Others

Pulsatilloside E

Cat.No: TN2117

Synonym: 3-O-B-D-葡萄糖( 1→4)-[ A -L-鼠李糖(1→2)]- A-L-阿拉伯糖 23-羟基羽扇豆20(29)-烯-28–酸- 28-O-鼠李糖(1→4)葡萄糖(1→6)葡萄糖苷,Pulchinenoside E,白头翁皂苷E

Target: Others

Prosaikogenin F

Cat.No: TN6864

Synonym: (2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol,前柴胡皂苷F

Target: Others

5-Methoxytryptophol

Cat.No: T13515

Synonym: 2-(5-Methoxy-1H-indol-3-yl)ethanol,Methoxytryptophol,5-甲氧基色醇

Target: Endogenous Metabolite

2',4,4',6'-Tetramethoxychalcone

Cat.No: TN7069

Synonym: 2',4,4',6'-TETRAMETHOXY

Target: Others

Cat.No: T21499

Synonym: Latrepirdine,Dimebon,Dimebone

Target: 5-HT Receptor

Methyl acetylsalicylate

Cat.No: TN6710

Synonym: ACETYLSALICYLIC ACID METHYL ESTER,乙酰水杨酸甲酯

Target: Others

(Z)-Aconitic acid

Cat.No: T8137

Synonym: 顺乌头酸,顺式乌头酸,Cls-Aconitic acid

Target: Others, Endogenous Metabolite

Cat.No: T5940

Synonym: 羟丙茶碱,7-(2-Hydroxypropyl)theophylline

Target: PDE, Adenosine Receptor

(R)-Citronellol

Cat.No: T8266

Synonym: D-Citronellol,(R)-(+)-β-Citronellol,(R)-3,7-二甲基-6-辛烯醇

Target: Others, Endogenous Metabolite

Cat.No: TN1539

Target: Others

Pulsatilla saponin H

Cat.No: TN2119

Synonym: 白头翁属皂苷H,白头翁皂苷 H,3-O-Β-D-葡萄糖( 1→4)-[ A -L-鼠李糖(1→2)]- A-L-阿拉伯糖常春藤配基- 28-O-鼠李糖(1→4)葡萄糖(1→6)葡萄糖苷

Target: Others

2,3-Diaminopropionic acid

Cat.No: T7335

Synonym: L-2,3-二氨基丙酸,L-2,3-Diaminopropionic acid

Target: Endogenous Metabolite

Furfuryl acetate

Cat.No: T8088

Synonym: 乙酸糠醇酯,乙酸糠酯

Target: Others

3-Phenylpropanal

Cat.No: T20312

Synonym: NSC-9271,Phenylpropyl aldehyde,NSC9271,NSC 9271

Target: Others

Ethyl acetoacetate

Cat.No: T15254

Synonym: Ethyl acetylacetate

Target: Others, Antibacterial

Cat.No: T15544

Synonym: NSC 321801

Target: Endogenous Metabolite

Trans-2-butene-1,4-dicarboxylic acid

Cat.No: T5246

Synonym: trans-2-Butene-1,4-dicarboxylic Acid,3-Hexenedioic Acid,trans-3-Hexenedioic Acid,β-Hydromuconic Acid,反式-2-丁烯-1,4-二甲酸

Target: Others, Endogenous Metabolite

16-Dehydroprogesterone

Cat.No: T8094

Synonym: 16-Dehydroprogesterone,16-去氢黄体酮

Target: Endogenous Metabolite

Cat.No: T21205

Synonym: 坡那甾酮A,AI3-44686

Target: Others

ATP disodium trihydrate

Cat.No: T64980

Synonym: Adenosine-5'-triphosphate disodium trihydrate

Target: Endogenous Metabolite

DL-Norepinephrine hydrochloride

Cat.No: T13655

Synonym: 去甲肾上腺素盐酸盐,Lys,DL-lysine

Target: Adrenergic Receptor

Cat.No: T14853

Synonym: FCE-21336,卡麦角林

Target: Dopamine Receptor, 5-HT Receptor, Autophagy

Cat.No: T21383

Synonym: Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine

Target: Others

2-Oleoylglycerol

Cat.No: T37526

Synonym: 2-Oleoyl Glycerol,2-OG,2-Monoolein

Target: GPR

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