86
13
3
2
57
Cat. No. | Product Name | ||
---|---|---|---|
L4020 | NO PAINS 化合物库 | 9384 compounds | |
TargetMol NO PAINS 化合物库包含 9384 个剔除了PAINS 的小分子活性化合物,可用于新药研发,信号通路研究,老药新用等研究。 | |||
L3600 | 细胞因子抑制剂库 | 604 compounds | |
604 个与细胞因子紧密相关的化合物集合,是高通量、高内涵筛选的良好载体; | |||
L7400 | 钠通道分子库 | 118 compounds | |
118 种钠通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0051 |
Penicillin-Streptomycin Solution (100×), Sterile
青霉素-链霉素双抗溶液(100×),灭菌 |
Solution in bottle | |
C0052 |
Penicillin-Streptomycin-Amphotericin B Solution (100×), Sterile
青霉素-链霉素-两性霉素B三抗溶液(100×),灭菌 |
Solution in bottle |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13736 |
Interferon receptor inducer-1
|
IFNAR | Immunology/Inflammation |
Interferon receptor inducer-1 是一种干扰素(IFN)受体诱导剂,可用于干扰素诱导参与的紊乱性疾病的研究。 | |||
T13613 |
ChX710
|
STING | Immunology/Inflammation |
ChX710可以引发 I 型干扰素对细胞溶质 DNA 的反应,其特异性细胞干扰素刺激基因 (ISG) 诱导 ISRE 启动子序列和干扰素调节因子 (IRF) 3 的磷酸化。 | |||
T22142 |
RO8191
RO4948191,CDM-3008 |
HCV Protease; HBV; JAK; IFNAR; STAT | Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Proteases/Proteasome; Stem Cells |
RO8191 (CDM-3008) 是干扰素 (IFN) 受体激动剂。它直接与 IFNα/β 受体 2 结合,激活 IFN 刺激的基因表达和 JAK/STAT 磷酸化。它通过具有干扰素样活性发挥 cccDNA 调节剂作用,并具有抗 HBV 活性。 | |||
T5154 |
C-176
C176,STING inhibitor 1 |
STING | Immunology/Inflammation |
C-176 (STING inhibitor 1) 是干扰素基因刺激受体的一种强效共价抑制剂。 | |||
T0244 |
Tilorone dihydrochloride
|
Influenza Virus; HIF/HIF Prolyl-Hydroxylase; IFNAR | Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; Microbiology/Virology |
Tilorone dihydrochloride 是一种具有口服活性的干扰素诱导剂,具有抗肿瘤和抗炎作用。 | |||
T77432 |
Anifrolumab
MDX-1333,MEDI-546 |
IFNAR | Immunology/Inflammation |
Anifrolumab(MEDI-546) 是一种有效的 I 型干扰素 (IFN) 受体拮抗剂,是一种靶向 IFN 的人源单克隆抗体。Anifrolumab 能抑制 I 型干扰素的活性,可用于预防和治疗系统性红斑狼疮 (SLE) 。 | |||
T4504 |
Triclocarban
Solubacter,Cutisan,Procutene,3,4,4′-Trichlorocarbanilide,三氯卡班 |
Antibacterial | Microbiology/Virology |
Triclocarban (Cutisan) 是一种抗菌剂,用于个人清洁产品。它有潜在干扰内分泌的作用,具有调节雄激素和雌激素活性以及其他激素介导的生物过程的能力。 | |||
T0872L |
Amprolium Hydrochloride
Amprovine,氨丙啉盐酸盐,Amprolio,Amprolium HCl,安普罗林盐酸盐 |
Parasite | Microbiology/Virology |
Amprolium Hydrochloride (Amprolium HCl) 是用于家禽的一种干扰硫胺素代谢的抗球虫药,通过抑制硫胺素吸收和碳水化合物合成而抑制球虫的硫胺转运。 | |||
T5486 |
RU.521
RU320521 |
DNA; cGAS | DNA Damage/DNA Repair; Immunology/Inflammation |
RU.521 (RU3205217) 是选择性的环状 GMP-AMP 合成酶 (cGAS) 抑制剂,抑制 cGAS 介导的干扰素上调。它也抑制dsDNA 激活受体的活性,IC50为 700 nM。它可降低来自 Aicardi-Goutières 综合征小鼠模型的巨噬细胞中干扰素的组成型表达。 | |||
T12933 |
SM-276001
|
TLR; COX | Immunology/Inflammation; Neuroscience |
SM-276001 是可口服的干扰素诱导剂,是选择性TLR7激动剂,可以诱导抗肿瘤免疫反应。 | |||
T13015 |
STING agonist-4
|
STING | Immunology/Inflammation |
STING agonist-4 是 是干扰素基因 (STING) 受体刺激剂的激动剂,IC50为 20 nM。 | |||
T6173 |
BI 2536
4-[[(7R)-8-环戊基-7-乙基-5,6,7,8-四氢-5-甲基-6-氧代-2-喋啶基]氨基]-3-甲氧基-N-(1-甲基-4-哌啶基)苯甲酰胺 |
Apoptosis; Epigenetic Reader Domain; PLK | Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic |
BI 2536 一种是PLK1和BRD4的双抑制剂,IC50分别为 0.83 和 25 nM。它抑制 IFNB 干扰素 β 基因转录。 | |||
T11344 |
G150
|
DNA; cGAS | DNA Damage/DNA Repair; Immunology/Inflammation |
G150 是高选择性h-cGAS 抑制剂,IC50值为 10.2 nM,用于抑制 dsDNA 引发的干扰素表达。 | |||
T7726 |
Triadimefon
|
Antifungal | Microbiology/Virology |
Triadimefon 是一种三唑类杀菌剂,可抑制羊毛甾醇 14α-去甲基化酶,干扰真菌麦角甾醇生物合成途径的氧化去甲基化反应,并可阻断赤霉素的生物合成。用于防治白粉病。 | |||
T67737 |
gp120-α4β7 binding inhibitor 11
|
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
gp120-α4β7 binding inhibitor 11是一种抗HIV 药物。gp120-α4β7 binding inhibitor 11干扰HIV 相关糖蛋白gp12G 与整合素α4β7的结合(IC50=1.64nM)。 | |||
T10252L2 |
ADU-S100 ammonium salt
ML RR-S2 CDA ammonium salt,MIW815 ammonium salt |
STING | Immunology/Inflammation |
ADU-S100 ammonium salt (ML RR-S2 CDA ammonium salt) 是干扰素基因刺激物的激活剂。 ADU-S100 ammonium salt 可导致有效的全身性肿瘤消退和免疫。 | |||
T9029 |
STING-IN-3
C-171 |
STING | Immunology/Inflammation |
STING-IN-3 (C-171) 是干扰素基因刺激物 (STING) 的抑制剂。 它与 STING 结合,抑制其棕榈酰化,并阻止 TBK1 的募集和磷酸化。 | |||
T5516 |
diABZI STING agonist-1 trihydrochloride
|
STING | Immunology/Inflammation |
diABZI STING agonist-1 trihydrochloride 是选择性的干扰素基因刺激受体(STING)激动剂,在人和小鼠中的 EC50值分别为 130 和 186 nM。 | |||
T82008 |
JG-2016
|
Histone Acetyltransferase | Chromatin/Epigenetic |
JG-2016,作为一种小分子组蛋白乙酰转移酶1 (HAT1) 抑制剂,抑制人类癌细胞系的生长,抑制纤维素中的酶活性,干扰肿瘤生长。 | |||
TP1186 |
Cyclo(Phe-Pro)
六氢-3-(苯基甲基)吡咯并[1,2-A]吡嗪-1,4-二酮,A-64863,Cyclo(phenylalanylprolyl) |
Others | Others |
Cyclo(Phe-Pro) (A-64863) 是创伤弧菌的群体感应分子,能够与 RIG-I 的特异性相互作用,阻碍 RIG-I 的多泛素化,并抑制 IRF-3 的激活和 I 型干扰素的产生。它提高 HCV 和流感病毒的易感性。 | |||
T8793 |
CBS1117
|
Influenza Virus | Microbiology/Virology |
CBS1117 是一种病毒进入抑制剂,对甲型流感病毒 A/Puerto Rico/8/34 的 IC50为 70 nM。它干扰血凝素介导的融合过程。 | |||
T0695 |
Avobenzone
阿伏苯宗,Butyl methoxydibenzoylmethane,BF2AVB |
Apoptosis; Estrogen Receptor/ERR; Others | Apoptosis; Endocrinology/Hormones; Others |
Avobenzone (Butyl methoxydibenzoylmethane) 是一种二苯甲酰甲烷内分泌干扰物,可直接与雌激素受体 β 结合,起到雌激素激动剂的作用。它是紫外线波段皮肤光防护防晒霜中应用最广泛的滤光剂之一。 | |||
T72482 |
Dazostinag disodium
|
STING | Immunology/Inflammation |
Dazostinag disodium (TAK-676) 是一种新型干扰素基因刺激剂 (STING) 激动剂,也是一种免疫系统调节剂,具有抗肿瘤活性,可激活树突状细胞、自然杀伤细胞和 T 细胞。 | |||
T11035 |
diABZI STING agonist-1 (Tautomerism)
diABZI STING agonist (Compound 3) |
STING | Immunology/Inflammation |
diABZI STING agonist-1 (Tautomerism) (diABZI STING agonist (Compound 3)) 是一个选择性的干扰素基因刺激受体 (STING) 的激动剂,其在人和小鼠中的 EC50 值分别为 130 nM 和 186 nM。。 | |||
T7194 |
CM-272
|
Apoptosis; DNA Methyltransferase; Histone Methyltransferase | Apoptosis; Chromatin/Epigenetic |
CM-272 是一种可逆底物竞争性双重G9a/DNA 甲基转移酶选择性抑制剂,具有抗肿瘤活性。它抑制细胞增殖并促进细胞凋亡,诱导干扰素刺激的基因和免疫原性细胞死亡。它抑制G9a、DNMT1、DNMT3A、DNMT3B 和GLP,IC50分别为 8 nM、382 nM、85 nM、1200 nM 和 2 nM。 | |||
T5317 |
Cridanimod
CMA,吖啶酮乙酸,XBIO-101,10-carboxymethyl-9-acridanone |
Progesterone Receptor; STING; IFNAR | Immunology/Inflammation; Others |
Cridanimod (10-carboxymethyl-9-acridanone, CMA) 是一种是小分子免疫调节剂和干扰素诱导剂,是一种孕酮受体激活剂,能够诱导 IFNα和IFNβ的表达,显著增加 PR 的表达。 | |||
TP1907L1 |
Dynamin inhibitory peptide, myristoylated acetate
Dynamin inhibitory peptide, myristoylated acetate(251634-22-7 free base) |
Dynamin | Cytoskeletal Signaling |
Dynamin inhibitory peptide, myristoylated acetate(251634-22-7 free base) 是一种 DynaMin 抑制剂,可干扰两性霉素与 dynamin 的结合。 DynaMin 抑制肽,肉豆蔻酰化 TFA 是肽的膜渗透形式,可防止内吞作用。 | |||
T12285 |
Ebopiprant
OBE022,OBE-022 |
Others | Others |
Ebopiprant (OBE022) 是一个可口服且具有选择性和高效性的前列腺素 F2α (PGF2α) 受体拮抗剂,干扰 PGF0126α 与 FPR 的结合,可用于研究肥胖。 | |||
T8798 |
MSA-2
|
STING | Immunology/Inflammation |
MSA-2 是可口服的非核苷酸 STING 激动剂,以具有纳摩尔亲和力的非共价二聚体形式与 STING 结合。它在同基因小鼠肿瘤模型中显示抗肿瘤活性,与抗 PD-1 协同作用,可刺激肿瘤分泌干扰素-β,诱导肿瘤消退,具有持久的抗肿瘤免疫。 | |||
T4998 |
Cefpodoxime proxetil
|
Antibacterial; Antibiotic | Microbiology/Virology |
Cefpodoxime Proxetil 是一种口服的广谱型抗生素。它与青霉素结合蛋白结合,抑制肽聚糖的合成,干扰细菌细胞壁的生物合成。 | |||
T76760 |
Sifalimumab
MDX-1103,MEDI-545 |
COX | Immunology/Inflammation; Neuroscience |
Sifalimumab (MEDI-545) 是一种靶向 IFNα 的单克隆抗体,通过结合干扰素-α 来抑制异常的免疫活动。Sifalimumab 用于治疗中度至重度系统性红斑狼疮。 | |||
T0116 |
Balofloxacin
|
DNA gyrase; Antibacterial; Antibiotic | DNA Damage/DNA Repair; Microbiology/Virology |
Balofloxacin 是一种具有口服活性的氟喹诺酮类抗生素,可通过干扰 DNA 促旋酶来抑制细菌 DNA 的合成,对革兰氏阴性,革兰氏阳性和厌氧菌具有广谱抗菌活性。它可研究呼吸道,肠道和泌尿道感染。 | |||
T12695 |
RBN-2397
|
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
RBN-2397 是一种有效的、选择性的、具有口服活性的跨物种 NAD+ 竞争性 PARP7 抑制剂,IC50 小于 3 nM。它选择性结合 PARP7 ,Kd 为0.001 μM,可恢复干扰素 I 型信号转导,有用于晚期或转移性实体肿瘤的研究潜力。 | |||
T15588 |
Iobenguane sulfate
硫酸碘苄胍 EP标准品,MIBG sulfate |
Others | Others |
Iobenguane sulfate (MIBG sulfate) 是一种具有抗肿瘤活性的神经递质去甲肾上腺素的类似物。Iobenguane sulfate 是一种高亲和力的霍乱毒素底物,干扰细胞单核(ADP-核糖基化)。放射性碘代 Iobenguane sulfate 可用于肾上腺肿瘤诊断和肿瘤靶向药物的研究。 | |||
T27034 |
CL075
3M002,CL-075 |
NF-κB; TLR; MyD88 | Immunology/Inflammation; NF-κB |
CL075 (3M002) 是一种选择性TLR8 激动剂。CL075具有免疫调节活性,通过触发 MyD88 依赖性信号通路,激活 NF-κB 和 IRF7 引发炎症性细胞因子和 I 型干扰素 (IFN) 的产生。 | |||
T16044 |
Methoprene
烯虫酯,ZR-515 |
Others | Others |
Methoprene (ZR-515) 是一种保幼激素模拟物和一种生物杀虫剂。Methoprene 作为昆虫生长调节剂,干扰昆虫的生命周期并阻止其成熟或繁殖。 | |||
T76742 |
Emapalumab
NI-0501 |
COX | Immunology/Inflammation; Neuroscience |
Emapalumab (NI-0501) 是一种人源化针对干扰素 γ 的人单克隆抗体的 IgG1 单克隆抗体,可阻断其与细胞表面受体的结合并激活炎症信号。Emapalumab 与游离的 IFN-γ 以及与其受体结合的 IFN-γ 具有高结合力 (Kd=1.4 pM)。Emapalumab 可用于噬血细胞性淋巴组织细胞增多症 (HLH) 的研究。 | |||
T10110 |
3-CPs
3-Carbethoxypsoralen,3-Ethoxycarbonylpsoralen |
Antibiotic | Microbiology/Virology |
3-CPs (3-Carbethoxypsoralen) 是一种博来霉素诱导的小鼠肺纤维化血清型荚膜多糖,属于补骨脂,可干扰抗体介导的细菌杀伤作用。3-CPs 可延缓博来霉素诱导的小鼠肺纤维化,可用于研究气道炎和哮喘。 | |||
T27586 |
IDX184
IDX-184,IDX 184 |
HCV Protease | Microbiology/Virology; Proteases/Proteasome |
IDX184 是一种有效的,具有口服活性的靶向 HCV 聚合酶抑制剂和核苷聚合酶抑制剂。IDX184 有效抑制 HCV 聚合酶 (IC50=0.31 μM,Ki=52.3 nM)。 IDX184是一种肝脏靶向核苷酸前药,具有抗HCV活性,可抑制HCV NS5B聚合酶,可与聚乙二醇化干扰素-α2a 和利巴韦林联合用于初治慢性丙型肝炎。 | |||
T0872 |
Amprolium
氨丙啉,安普罗林 |
Others; Parasite | Microbiology/Virology; Others |
Amprolium 是一种干扰硫胺素代谢的兽用球虫抑制剂。 | |||
T1023 |
Cefoxitin sodium
Cenomycin,MK-306,头孢西丁钠,Betacef,Merxin |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefoxitin sodium (Betacef) 是一种头霉素类抗生素。Cefoxitin 干扰细胞壁合成。它对革兰氏阴性和革兰氏阳性菌有活性。 | |||
T80570 |
Dazukibart
|
IFNAR | Immunology/Inflammation |
Dazukibart为针对小鼠源性干扰素β1(IFNB1)设计的人源化IgG1κ单克隆抗体。 | |||
T82803 |
Butylparaben sodium
Butyl parahydroxybenzoate sodium,Butyl 4-hydroxybenzoate sodium |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Butylparaben sodium 可通过干扰激素控制和/或破坏 RNA 及蛋白质合成来显著影响睾丸中的精子发生晚期。 | |||
T62678 | YE6144 | ||
YE6144 是一种典型的干扰素调节因子 5 (IRF5) 抑制剂。YE6144 能够抑制 IRF5 磷酸化,进而选择性抑制 IRF5 活性。 | |||
T83147 |
Albinterferon alfa-2B
alb-IFN |
||
Albinterferon alfa-2B (alb-IFN) 是融合了人白蛋白基因的重组干扰素 alfa-2b。它适用于慢性丙型肝炎的研究。 | |||
T73687 |
G-418
|
||
G-418 (Geneticin),一种氨基糖苷类抗生素,其结构与庆大霉素相似,既对真核细胞也对原核细胞具有毒性,主要通过干扰蛋白质合成发挥作用。 | |||
T76930 | Bifarcept | ||
Bifarcept为一种针对干扰素受体I型(IFN-RI)的重组抗体,能与IFN-β结合,从而延长其在血清中的半衰期。 | |||
T81697 | NBI-6024 | ||
NBI-6024 是一种变构肽配体(APL),可被1型糖尿病患者中产生炎症性干扰素-γ的T辅助淋巴细胞识别的表位。 | |||
T73746 | diABZI STING agonist-1 | ||
diABZISTINGagonist-1是一种针对干扰素基因刺激受体(STING)的选择性激动剂,其在人类和小鼠中的EC50值分别是130 nM和186 nM。 | |||
T63588 | Antibacterial agent 89 | ||
Antibacterial agent 89 是强效的抗菌剂,能够干扰细菌转录的过程,表现出抗梭菌效果。Antibacterial agent 89 能够抑制细胞毒素的释放和 β'CH-σ 相互作用。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2862 |
Desaminotyrosine
Phloretate,3-(4-Hydroxyphenyl)propanoic acid,Hydro-p-coumaric acid,对羟基苯丙酸,3-(4-Hydroxyphenyl)propionic acid,Phloretic acid,根皮酸 |
Others; Influenza Virus; Endogenous Metabolite | Metabolism; Microbiology/Virology; Others |
Desaminotyrosine (3-(4-Hydroxyphenyl)propionic acid) 是一种与微生物相关的代谢物,通过增强 I 型干扰素信号传导来预防流感。 | |||
T0788 |
Spectinomycin dihydrochloride
淋必治,Spectinomycin 2HCl,盐酸奇霉素,Actinospectacin |
ribosome; Antibacterial; Antibiotic | Microbiology/Virology |
Spectinomycin dihydrochloride (Actinospectacin) 是一种能与细菌核糖体的30S 亚基结合,干扰蛋白质合成的抗生素。 | |||
T6758 |
Anisomycin
茴香霉素,Flagecidin,NSC 76712,Wuningmeisu C |
Apoptosis; DNA/RNA Synthesis; Antibacterial; Antibiotic; JNK | Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; MAPK; Microbiology/Virology |
Anisomycin (NSC-76712) 是一种从各种链霉菌属中分离出来的抗生素。 它通过抑制肽基转移酶或 80S 核糖体系统来干扰蛋白质和 DNA 合成。 | |||
T7004 |
Tubercidin
结核菌素,杀结核菌素,Sparsomycin A,7-Deazaadenosine |
Influenza Virus; DNA/RNA Synthesis; Antibacterial; Antibiotic | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Tubercidin (Sparsomycin A) 是从Streptomyces tubercidicus 得到的抗生素,抑制粪链球菌生长的IC50值为 0.02 μM。它是腺苷磷酸化酶的弱抑制剂,并干扰腺苷和 AMP 的磷酸化。它有抗病毒作用。 | |||
T21430 |
Oxytetracycline Hydrochloride
Biosolvomycin,盐酸土霉素,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin |
Antiviral; Endogenous Metabolite; Antibacterial; HSV | Immunology/Inflammation; Metabolism; Microbiology/Virology |
Oxytetracycline Hydrochloride (Dalimycin) 是由 Streptomyces rimosus 生产的,一种具有抗菌活性的四环素衍生物。它干扰氨酰-tRNA 与 mRNA-核糖体复合物的结合,从而阻止肽延伸并抑制蛋白质合成。 | |||
T64911 |
Blasticidin S HCl
|
Antibiotic | Microbiology/Virology |
Blasticidin S HCl 是从 Streptomyces griseochromogenes 中分离的肽基核苷类抗生素 (antibiotic),主要通过干扰核糖体中肽键的形成从而抑制原核细胞和真核细胞蛋白的合成。 | |||
T64353 |
4-tert-Octylphenol
|
Endogenous Metabolite | Metabolism |
4-tert-Octylphenol 是一种干扰内分泌的化学物质及雌激素药物,能诱导子代小鼠脑神经元祖细胞的凋亡,并通过减少溴脱氧尿苷(BrdU)、有丝分裂标志物Ki67以及磷酸组蛋白H3(p-Histone-H3)的表达,导致神经元祖细胞的增殖减少。这种物质不仅会干扰小鼠的大脑发育,还会影响其行为。 | |||
T1022 |
Hygromycin B
潮霉素B,Hygrovetine |
ribosome; Antibacterial; Antibiotic; Antifungal | Microbiology/Virology |
Hygromycin B (Hygrovetine) 是一种氨基糖苷类抗生素,通过干扰易位并导致 70S 核糖体的错误翻译来抑制蛋白质合成。Hygromycin B 可用于筛选转染 hph 或 hyg 抗性基因的原核或者真核细胞。 | |||
T20643 |
Cefoxitin
Rephoxitin,Cefoxitinum |
Cell wall; Antibacterial; Antibiotic | Immunology/Inflammation; Microbiology/Virology |
Cefoxitin (Rephoxitin) 是一种广谱的、可口服的第二代头孢霉素类抗生素。Cefoxitin 干扰细菌细胞壁的合成。其活性谱包括革兰氏阴性和革兰氏阳性菌,通常用于腹腔感染、盆腔感染和某些类型的妇科感染等腹部,对厌氧菌具有高效性。 | |||
T3S0027 |
Picropodophyllotoxin
AXL 1717,Picropodophyllin,苦鬼臼毒素 |
IGF-1R | Tyrosine Kinase/Adaptors |
Picropodophyllotoxin (AXL 1717) 是一种环木脂素生物碱,存在于五月树(Podophyllum peltatum) 中,是一种具有潜在抗肿瘤活性的胰岛素样生长因子 1 受体 (IGF1R) 的小分子抑制剂。它特异性抑制 IGF1R 的活性并下调细胞表达,而不干扰其他生长因子受体的活性,例如胰岛素受体、表皮生长因子、血小板衍生生长因子、成纤维细胞生长因子和肥大/干细胞生长因子 (KIT) )。该药剂在抑制肿瘤细胞增殖和诱导肿瘤细胞凋亡方面显示出有效的活性。 IGF1R 是一种在多种人类癌症中过度表达的受体酪氨酸激酶,在多种癌细胞的生长和存活中起关键作用。 | |||
TN1163 |
2'-Hydroxychalcone
|
Others | Others |
2'-Hydroxychalcone 是一种药物合成中间体,可用于合成黄酮类化合物。负载在纳米乳液中的2'-Hydroxychalcone 在Danio rerio 模型对副球孢子菌显示出杀真菌活性。2'-Hydroxychalcone 通过负载脂质的Hepg2细胞中的氧化应激诱导细胞毒性。2'-Hydroxychalcone 抑制通过逆转录聚合酶链反应确定的肿瘤坏死因子-α诱导ICAM-1,VCAM-1和E-选择素的稳态转录水平,因此可能会干扰其基因的转录。 | |||
T73717 | cGAMP diammonium | ||
cGAMP (Cyclic GMP-AMPP) diammonium 是一种内源性第二信使,通过触发干扰素的产生来响应胞浆 DNA。它通过激活干扰素基因刺激因子(STING),启动信号级联,进而导致I型干扰素及其他免疫介质的生成。 | |||
T13606L |
cGAMP disodium
|
||
cGAMP disodium 是在细菌中发现的一种环二核苷酸 (CDN) ,可作为内源性第二信使,影响干扰素的产生以响应胞浆 DNA。cGAMP disodium 通过激活干扰素基因刺激因子 (STING)使 I 型干扰素和其他免疫介质的信号产生级联现象。cGAMP disodium 是一种有效的舌下免疫佐剂,能使免疫功能(血清抗 PA 中和和气道分泌物抗 PA SIgA 反应) 更好的发挥作用。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02827 |
IFN gamma Protein, Rat, Recombinant (hFc)
interferon, γ,干扰素,interferon, gamma,IFN γ |
Rat | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ... | |||
TMPY-03356 |
IFN gamma Protein, Mouse, Recombinant
IFN γ,interferon, γ,interferon, gamma,Ifg,IFN-g,干扰素 |
Mouse | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ... | |||
TMPY-00007 |
Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant
interferon, alpha 2,Ifa2,interferon, α2,干扰素,Interfe... |
Mouse | Yeast |
IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-α genes, a t... | |||
TMPY-06983 |
IFN gamma Protein, Human, Recombinant (E. coli)
Interferon Gamma,IFN γ,IFN gamma,IFG,IFI,干扰素,Interf... |
Human | E. coli |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ... | |||
TMPY-02515 |
Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc)
IFN-alphaJ,干扰素,IFNA-J,IFN-αJ,interferon, alpha 7,in... |
Human | HEK293 |
Interferon alpha-7(IFNA7) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens o... | |||
TMPY-01714 |
IFN gamma Protein, Human, Recombinant
IFI,interferon, γ,IFN γ,IFG,IFN gamma,interferon, gamma,... |
Human | CHO |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ... | |||
TMPY-03467 |
IFN-beta Protein, Mouse, Recombinant
Ifb,IFN-β,interferon, beta 1, fibroblast,干扰素,IFNB,I... |
Mouse | HEK293 |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, parasites, and tumor cells. Interferon-beta (IFN beta) is an extracellular protein mediator of host defense and homeostasis. IFN beta has well-established direct antiviral, antiproliferative, and immunomodulatory properties. Recombinant IFN beta is approved for the treatment of relaps... | |||
TMPY-02566 |
Interferon alpha 4/IFNA4 Protein, Human, Recombinant (His)
干扰素,interferon, α4,MGC142200,interferon, alpha 4,IN... |
Human | Baculovirus-Insect Cells |
Interferon, alpha 4 (IFNA4) belongs to the alpha/beta interferon family. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410 and can be distinguished by selective restriction enzyme analysis. Interferons are produced by macrophages, IFN-alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytok... | |||
TMPK-00047 |
IFN gamma Protein, Human, Recombinant (His & Avi)
IFN gamma,interferon,Interferon-γ,γ,IFI,干扰素,Interfe... |
Human | HEK293 |
Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experimental animals significantly predisposes the host to microbial infection, a result that validates the physiologic importance of this cytokine in preventing infectious disease. IFN gamma Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi ... | |||
TMPY-00831 |
IFN-beta Protein, Human, Recombinant (hFc)
IFNB,IFN-β,Interferon beta,interferon, beta 1, fibroblast,In... |
Human | HEK293 |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, parasites, and tumor cells. Interferon-beta (IFN beta) is an extracellular protein mediator of host defense and homeostasis. IFN beta has well-established direct antiviral, antiproliferative, and immunomodulatory properties. Recombinant IFN beta is approved for the treatment of relaps... | |||
TMPY-03145 |
IFN-beta Protein, Human, Recombinant
IFN-β,interferon, β1, fibroblast,IFNB,IFB,IFF,Interferon β,I... |
Human | CHO |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, parasites, and tumor cells. Interferon-beta (IFN beta) is an extracellular protein mediator of host defense and homeostasis. IFN beta has well-established direct antiviral, antiproliferative, and immunomodulatory properties. Recombinant IFN beta is approved for the treatment of relaps... | |||
TMPY-04191 |
IFN gamma Protein, Rhesus, Recombinant (His)
interferon, γ,IFN γ,干扰素,interferon, gamma |
Rhesus | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ... | |||
TMPY-00527 |
IFN gamma Protein, Rhesus, Recombinant
interferon, gamma,干扰素,IFN γ,interferon, γ |
Rhesus | E. coli |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ... | |||
TMPY-04578 |
Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His)
Interferon α1,IFN-alphaD,IFN-αD,IFN-α,interferon, alpha 1,IF... |
Human | Yeast |
IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites, or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune... | |||
TMPY-03664 |
IFN gamma Protein, Ferret, Recombinant (His)
interferon, gamma,interferon, γ,IFN γ,干扰素 |
Ferret | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ... | |||
TMPY-03072 |
IFN-omega Protein, Human, Recombinant (His)
IFN-ω,IFN-ω 1,interferon omega-1,IFNW1,interferon ω-1,interf... |
Human | HEK293 |
IFNs are a large family of proteins having antiviral, antiproliferative, and immunomodulatory effects, and are divided into two major classes, type I and type II, based on differences in receptor binding and nucleotide sequence. Type I IFNs consist of IFN α, β, τ, and ω and bind to the type I IFN receptor, whereas IFN-γ is the only type II IFN and is specific for the type II IFN receptor. Human IFN-ω, was identified by three independent groups in 1985 and is structurally related to IFN-α and -β.... | |||
TMPY-00265 |
Interferon alpha 2/IFNA2 Protein, Human, Recombinant
IFNAB,干扰素,IFNA2B,IFN-alphaA,INFA2,interferon, alpha... |
Human | Yeast |
IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-α genes, a t... | |||
TMPY-02323 |
IFN gamma Protein, Mouse, Recombinant (His)
IFN-g,Ifg,干扰素,interferon, γ,interferon, gamma,IFN γ |
Mouse | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ... | |||
TMPY-02322 |
IFN gamma Protein, Mouse, Recombinant (hFc)
IFN γ,Ifg,IFN-g,interferon, gamma,interferon, γ,干扰素 |
Mouse | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ... | |||
TMPY-03720 |
Interferon alpha 14/IFNA14 Protein, Rhesus, Recombinant (His)
interferon, alpha 14,干扰素,interferon, α14 |
Rhesus | Yeast |
Interferon alpha 14/IFNA14 Protein, Rhesus, Recombinant (His) is expressed in Yeast with His tag. The predicted molecular weight is 21 kDa. Accession number: A0A7R8C3D1 | |||
TMPJ-00746 |
IFN-alpha 2b/IFNA2 Protein, Human, Recombinant
干扰素,IFNA2,Interferon α-2,Interferon α-A,Interferon ... |
Human | E. coli |
At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes differ in their sequences by only one or two positions. Naturally occurring variants also include proteins that are truncated by 10 amino acids at the ca... | |||
TMPJ-00745 |
IFN-alpha 2a/IFNA2 Protein, Human, Recombinant
Interferon α-2,IFNA2,干扰素,IFN α2a,IFN-α-2,IFN-Alpha-... |
Human | E. coli |
At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes only differ in their sequences by one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-ter... | |||
TMPY-02865 |
Interferon alpha 1/IFNA1 Protein, Rat, Recombinant (His)
interferon, alpha 1,Interferon α1,interferon, α1,干扰素 |
Rat | HEK293 |
IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites, or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune... | |||
TMPY-02743 |
Interferon alpha 1/IFNA1 Protein, Rat, Recombinant (hFc)
Interferon α1,干扰素,interferon, α1,interferon, alpha ... |
Rat | HEK293 |
IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites, or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune... | |||
TMPY-00096 |
Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant
interferon, alpha 2,interferon, α2,干扰素,Interferon α... |
Rhesus | Yeast |
IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-α genes, a t... | |||
TMPY-03735 |
Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (His)
Interferon α2/IFNA2,interferon, α2,interferon, alpha 2,干... |
Rhesus | HEK293 |
IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-α genes, a t... | |||
TMPY-03319 |
Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (mFc)
interferon, alpha 2,interferon, α2,干扰素,Interferon α... |
Rhesus | HEK293 |
IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-α genes, a t... | |||
TMPY-04634 |
Interferon alpha 1/IFNA1 Protein, Mouse, Recombinant (His)
Ifa1,Interferon α1,interferon, α1,干扰素,interferon, a... |
Mouse | Yeast |
IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites, or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune... | |||
TMPY-04664 |
Interferon alpha 4/IFNA4 Protein, Cynomolgus, Recombinant (mFc)
IFNA4,干扰素,interferon, alpha 4,interferon, α4 |
Cynomolgus | HEK293 |
Interferon, alpha 4 (IFNA4) belongs to the alpha/beta interferon family. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410 and can be distinguished by selective restriction enzyme analysis. Interferons are produced by macrophages, IFN-alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytok... | |||
TMPY-02661 |
Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant (hFc)
干扰素,Ifa2,interferon, alpha 2,interferon, α2,Interfe... |
Mouse | HEK293 |
IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-α genes, a t... | |||
TMPY-03027 |
Interferon alpha 4/IFNA4 Protein, Rat, Recombinant (hFc)
IFNA4,interferon, α4,interferon, alpha 4,干扰素 |
Rat | HEK293 |
Interferon, alpha 4 (IFNA4) belongs to the alpha/beta interferon family. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410 and can be distinguished by selective restriction enzyme analysis. Interferons are produced by macrophages, IFN-alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytok... | |||
TMPY-03815 |
Interferon alpha 14/IFNA14 Protein, Mouse, Recombinant (His)
interferon, alpha 14,OTTMUSG00000007662,干扰素,interfe... |
Mouse | HEK293 |
Interferon alpha 14/IFNA14 Protein, Mouse, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 20.5 kDa. Accession number: Q810G3 | |||
TMPY-03891 |
IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (His)
IFN-α 13,干扰素,interferon, alpha 13,interferon, α13,R... |
Mouse | HEK293 |
IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 20.5 kDa. Accession number: Q80SU4 | |||
TMPY-03828 |
IFN-beta Protein, Rhesus, Recombinant (mFc)
interferon, beta 1, fibroblast,干扰素,interferon, β1, ... |
Rhesus | HEK293 |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, parasites, and tumor cells. Interferon-beta (IFN beta) is an extracellular protein mediator of host defense and homeostasis. IFN beta has well-established direct antiviral, antiproliferative, and immunomodulatory properties. Recombinant IFN beta is approved for the treatment of relaps... | |||
TMPY-02345 |
Interferon alpha 14/IFNA14 Protein, Mouse, Recombinant (hFc)
interferon, alpha 14,interferon, α14,OTTMUSG00000007662,... |
Mouse | HEK293 |
Interferon alpha 14/IFNA14 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 47.4 kDa. Accession number: Q810G3 | |||
TMPY-03320 |
IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (hFc)
IFN-α 13,干扰素,interferon, alpha 13,IFNA13,interferon... |
Cynomolgus | HEK293 |
IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 46.4 kDa. Accession number: G7NFW4 | |||
TMPY-03375 |
IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (His)
IFNA13,干扰素,interferon, α13,interferon, alpha 13,IFN... |
Cynomolgus | HEK293 |
IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 20.8 kDa. Accession number: G7NFW4 | |||
TMPY-03130 |
interferon alpha 5/IFNA5 Protein, Rat, Recombinant (His)
interferon, alpha 5,IFNA5,干扰素,interferon-α,interfer... |
Rat | HEK293 |
Interferon, alpha 5 (IFNA5) belongs to the alpha/beta interferon family. IFNA5 is the only IFNA subtype detected in normal liver, while a mixture of subtypes is observed in the liver tissue of patients with chronic hepatitis C. Interferons are produced by macrophages, IFN-alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytokine to be produced by recombinant DNA technology, has emerged as ... | |||
TMPY-02347 |
IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (hFc)
interferon, alpha 13,RP23-139P14.1,IFN-α 13,干扰素,int... |
Mouse | HEK293 |
IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 47.5 kDa. Accession number: Q80SU4 | |||
TMPY-02526 |
interferon alpha 5/IFNA5 Protein, Mouse, Recombinant (His)
IFNA5,Ifa5,interferon-α,干扰素,interferon, alpha 5,int... |
Mouse | HEK293 |
Interferon, alpha 5 (IFNA5) belongs to the alpha/beta interferon family. IFNA5 is the only IFNA subtype detected in normal liver, while a mixture of subtypes is observed in the liver tissue of patients with chronic hepatitis C. Interferons are produced by macrophages, IFN-alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytokine to be produced by recombinant DNA technology, has emerged as ... | |||
TMPY-03355 |
interferon alpha 5/IFNA5 Protein, Mouse, Recombinant (hFc)
interferon, α5,interferon, alpha 5,IFNA5,interferon-α,干扰... |
Mouse | HEK293 |
Interferon, alpha 5 (IFNA5) belongs to the alpha/beta interferon family. IFNA5 is the only IFNA subtype detected in normal liver, while a mixture of subtypes is observed in the liver tissue of patients with chronic hepatitis C. Interferons are produced by macrophages, IFN-alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytokine to be produced by recombinant DNA technology, has emerged as ... | |||
TMPY-04841 |
Interferon alpha 7/IFNA7 Protein, Human, Recombinant (His)
interferon, alpha 7,interferon, α7,IFN-αJ,IFNA-J,IFN-alphaJ,... |
Human | Yeast |
Interferon alpha-7(IFNA7) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens o... | |||
TMPY-02346 |
Interferon alpha 4/IFNA4 Protein, Mouse, Recombinant (hFc)
RP23-139P14.30-001,干扰素,interferon, alpha 4,interfer... |
Mouse | HEK293 |
Interferon, alpha 4 (IFNA4) belongs to the alpha/beta interferon family. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410 and can be distinguished by selective restriction enzyme analysis. Interferons are produced by macrophages, IFN-alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytok... | |||
TMPY-00829 |
Interferon alpha 4/IFNA4 Protein, Human, Recombinant (hFc)
interferon, α4,IFN-α4a,干扰素,interferon, alpha 4,MGC1... |
Human | HEK293 |
Interferon, alpha 4 (IFNA4) belongs to the alpha/beta interferon family. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410 and can be distinguished by selective restriction enzyme analysis. Interferons are produced by macrophages, IFN-alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytok... | |||
TMPY-03892 |
Interferon alpha 4/IFNA4 Protein, Mouse, Recombinant (His)
MGC143607,RP23-139P14.30-001,干扰素,Ifa4,interferon, α... |
Mouse | HEK293 |
Interferon, alpha 4 (IFNA4) belongs to the alpha/beta interferon family. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410 and can be distinguished by selective restriction enzyme analysis. Interferons are produced by macrophages, IFN-alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytok... | |||
TMPY-02456 |
IFN-beta Protein, Mouse, Recombinant (hFc)
Ifb,interferon, β1, fibroblast,IFN-β,干扰素,interferon... |
Mouse | HEK293 |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, parasites, and tumor cells. Interferon-beta (IFN beta) is an extracellular protein mediator of host defense and homeostasis. IFN beta has well-established direct antiviral, antiproliferative, and immunomodulatory properties. Recombinant IFN beta is approved for the treatment of relaps... | |||
TMPY-02516 |
Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc)
interferon, α10,interferon, alpha 10,IFN-alphaC,MGC119879, |
Human | HEK293 |
Interferon alpha-10 (IFNA10) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogen... | |||
TMPK-00048 |
IFN gamma Protein, Human, Recombinant (His & Avi), Biotinylated
IFNγ,IFN γ/IFNG,gamma,γ,IFG,IFN γ,IFN gamma,Interferon-gamma... |
Human | HEK293 |
Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experimental animals significantly predisposes the host to microbial infection, a result that validates the physiologic importance of this cytokine in preventing infectious disease. | |||
TMPY-06407 |
Interferon alpha 2/IFNA2 Protein, Human, Recombinant (hFc)
IFN-αA,INFA2,干扰素,Interferon α2,IFNA2B,interferon, α... |
Human | HEK293 |
IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-α genes, a t... | |||
TMPY-00833 |
IFN-omega Protein, Human, Recombinant (hFc)
干扰素,IFNW1,IFN-ω 1,interferon ω-1,IFN-omega 1,IFN-ω,... |
Human | HEK293 |
IFNs are a large family of proteins having antiviral, antiproliferative, and immunomodulatory effects, and are divided into two major classes, type I and type II, based on differences in receptor binding and nucleotide sequence. Type I IFNs consist of IFN α, β, τ, and ω and bind to the type I IFN receptor, whereas IFN-γ is the only type II IFN and is specific for the type II IFN receptor. Human IFN-ω, was identified by three independent groups in 1985 and is structurally related to IFN-α and -β.... | |||
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