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1607

抑制剂 & 化合物

679

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T37422L	Ras Inhibitory Peptide acetate Ras Inhibitory Peptide acetate(159088-48-9 Free base)	Ras	GPCR/G Protein; MAPK
	Ras Inhibitory Peptide acetate 是一种参与 Ras 依赖性信号通路的肽，Ras 在致癌受体引发的人类癌症中起重要作用。
T21798L	Dynamin inhibitory peptide Acetate Dynamin inhibitory peptide Acetate(251634-21-6 Free base)	GTPase	GPCR/G Protein
	Dynamin inhibitory peptide Acetate 是一种具有序列 Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro 的肽，可抑制 GTPase dynamin。
TP1615L	IKKγ NBD Inhibitory Peptide acetate IKKγ NBD Inhibitory Peptide acetate(372146-18-4 free base)	NF-κB	NF-κB
	IKKγ NBD Inhibitory Peptide acetate 是一种 NEMO 结合结构域肽（NBD 肽）乙酸盐，对应于 NEMO 氨基末端 α-螺旋区域。它显示可阻断 TNF-α 诱导的 NF-kB 活化。
TP1907L1	Dynamin inhibitory peptide, myristoylated acetate Dynamin inhibitory peptide, myristoylated acetate(251634-22-7 free base)	Dynamin	Cytoskeletal Signaling
	Dynamin inhibitory peptide, myristoylated acetate(251634-22-7 free base) 是一种 DynaMin 抑制剂，可干扰两性霉素与 dynamin 的结合。 DynaMin 抑制肽，肉豆蔻酰化 TFA 是肽的膜渗透形式，可防止内吞作用。
TP2310	Autocamtide-2-related inhibitory peptide	CaMK; Autophagy	Autophagy; Neuroscience
	Autocamtide-2-related inhibitory peptide 是一种高度特异性和有效的 CaMKII 抑制剂，IC50 为 40 nM。
TP1216	CaM kinase II inhibitor TFA salt Autocamtide-2-related inhibitory peptide (TFA)	CaMK	Neuroscience
	CaM kinase II inhibitor TFA salt (Autocamtide-2-related inhibitory peptide(TFA)) 是一种高度特异性和有效的 CaMKII 抑制剂，IC50 为 40 nM。
TP1921L1	Autocamtide-2-related inhibitory peptide, myristoylated acetate(201422-04-0 free base)	CaMK; Autophagy	Autophagy; Neuroscience
	Autocamtide-2-related inhibitory peptide, myristoylated acetate 是CaM 激酶II 抑制剂;是 Autocamtide-2相关抑制肽的增强细胞渗透性衍生物。
T37422	Ras Inhibitory Peptide
	Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to the activation of ERK. Ras inhibitory peptide is a synthetic peptide that contains the sequence PVPPR, which corresponds to a region within human Sos1 that interacts with an SH3 domain of Grb2. It specifically blocks the interaction of the GEF with Grb2, preventing an interaction ...
TP1615	IKKγ NBD Inhibitory Peptide
	A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is vital for t
TP1907	DynaMin inhibitory peptide, myristoylated
	Cell-permeable version of dynamin inhibitory peptide, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Reduces NMDA receptor internalization.
TP2192	Cdk2/Cyclin Inhibitory Peptide I	Others	Others
	Cyclin-dependent kinase 2 also known as cell division protein kinase 2. The protein encoded by this gene is a member of the cyclin-dependent kinase family of Ser/Thr protein kinases. This protein kinase is highly similar to the gene products of S. cerevis
TP2351	Renin inhibitory peptide Pro-his-pro-phe-his-phe-phe-val-tyr-lys
	Renin inhibitory peptide is an analog of angiotensinogen.
T78543	Acetyl Gastric Inhibitory Peptide (human) TFA Human N-acetyl GIP TFA
	AcetylGastric Inhibitory Peptide(human) TFA 是一种葡萄糖依赖性胰岛素释放多肽的改性脂肪酸衍生物，具有增强的抗高血糖和促胰岛素作用。它主要用于糖尿病、胰岛素抵抗和肥胖的科研领域。
TP2351L	Renin inhibitory peptide, statine SCRIP,Iva-his-pro-phe-his-sta-leu-phe-NH2
	Renin inhibitory peptide, statine is a effective, specific statine-containing renin inhibitor.
TP2039	Dynamin inhibitory peptide, myristoylated (control)
	Control peptide version of dynamin inhibitory peptide, myristoylated, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. In contrast to dynamin inhibitory peptide, has no significant eff
T76309	Gastric Inhibitory Peptide, porcine
	Gastric Inhibitory Peptide, porcine 为葡萄糖依赖性胰岛素促进多肽，包含42个氨基酸构成的肠道激素，对脂肪及葡萄糖代谢产生影响。
T80269	AC3-I, myristoylated Autocamtide-3 Derived Inhibitory Peptide	CaMK	Neuroscience
	AC3-I, myristoylated 为一种具有高度特异性的 CaMKII 抑制剂，为 Autocamtide-3 衍生的生物活性肽。通过将 Autocamtide-3 中的 Thr-9 磷酸化位点替换为 Ala，赋予该肽抗蛋白水解能力，从而制备出该肉豆蔻酰化形式。
T75796	Dynamin inhibitory peptide TFA
	Dynamininhibitory peptide TFA 竞争性地阻止了动力蛋白 (dynamin) 与两性纤维蛋白的结合，从而防止了内吞作用。Dynamininhibitory peptide TFA 阻断多巴胺 D3对 GABAA 受体的作用。
T37589	GIP (3-42), human Gastric Inhibitory Polypeptide (3-42) (human)	IGF-1R	Tyrosine Kinase/Adaptors
	GIP (3-42), human (Gastric Inhibitory Polypeptide (3-42) (human)) 是一种多肽，可充当葡萄糖依赖性促胰岛素多肽 (GIP) 受体拮抗剂，在体内调节胰岛素分泌和 GIP 的代谢作用，可用于研究2型糖尿病。
T76310	Acetyl Gastric Inhibitory Peptide (human)
	AcetylGastric Inhibitory Peptide(human)，一种脂肪酸衍生的葡萄糖依赖性胰岛素多肽类似物，具备改善抗高血糖和胰岛素敏感性的特性。适用于糖尿病、胰岛素抵抗及肥胖研究。
T76377	Cdk2/Cyclin Inhibitory Peptide II
	Cdk2/Cyclin Inhibitory Peptide II (Tat-LDL) 是一种 CDK2抑制剂，能以剂量依赖的方式杀死 U2OS 骨肉瘤细胞。
T76024	IKKγ NBD Inhibitory Peptide TFA
	IKKγ NBD 抑制肽 TFA 是一种高度特异性的NF-κB 抑制剂。IKKγ NBD 抑制肽 TFA 通过阻断 IKKγ/NEMO 结合域 (NBD) 与 IKKα 和 IKKβ 之间的相互作用，而阻断 TNF-α 诱导的NF-κB 激活。IKKγ NBD 抑制肽 TFA 可显著降低炎症、改善脑缺血所致的神经功能缺损。
T80954	TREM-1 inhibitory peptide M3
	TREM-1 inhibitory peptide M3为一种配体依赖的TREM-1拮抗剂。该化合物能够有效抑制全身及肺部促炎细胞因子与趋化因子的产生，有助于缓解急性肺损伤。
T76308	Gastric Inhibitory Polypeptide (1-30), porcine
	Gastric Inhibitory Polypeptide (1-30), porcine 缺乏天然胃抑制多肽 (GIP) C 端 12 个氨基酸残基，能够增强胰岛素和生长抑素的释放而发挥生物活性。
T76307	[Tyr0] Gastric Inhibitory Peptide (23-42), human
	[Tyr0]Gastric Inhibitory Peptide(23-42), human，属于葡萄糖依赖性促胰岛素多肽（GIP）类，具有抑制胃酸分泌并促进胰岛素释放的功能。它在糖尿病和肥胖症的研究中有应用价值。
T75736	Autocamtide-2-related inhibitory peptide TFA
	Autocamtide-2-related inhibitory peptide (TFA) 是高度特异性的、CaMKII 的有效抑制剂，其IC50值为 40 nM。
T83694	Gastric Inhibitory Peptide (1-42) (porcine) TFA GIP (1-42),Glucose-dependent Insulinotropic Polypeptide (1-42)
	胃抑制肽(GIP) (1-42)是一种内源性的42氨基酸肽类肠促素激素，能诱导胰岛素分泌。该激素在肠道神经内分泌K细胞和颌下腺中表达，并在餐后释放到循环中。GIP (1-42)抑制由组胺、五肽和胰岛素引起的胃酸和胃蛋白酶分泌，增加葡萄糖诱导的胰岛素释放，并在大鼠中刺激胃排空。
T83710	Gastric Inhibitory Peptide (22-51) (human) TFA GIP (22-51),Glucose-dependent Insulinotropic Peptide (22-51)
	胃抑制肽(GIP) (22-51) 是一种具有30个氨基酸的前动脉硬化肽，对应于GIP前体蛋白proGIP的第22至51个氨基酸残基，已在人类血浆中发现。在1 µM的浓度下使用，该肽能引起在巨峰细胞分化的THP-1细胞和分离的人类主动脉内皮细胞中IκB-α的降解和NF-κB的核转移。在体内，GIP (22-51) 增加了ApoE-/-小鼠的动脉粥样硬化病变面积和斑块形成。
T75737	Autocamtide-2-related inhibitory peptide, myristoylated TFA
	Autocamtide-2-related inhibitory peptide, myristoylated TFA 是 Autocamtide-2-related inhibitory peptide 烷基化修饰后的形式。 Autocamtide-2-related inhibitory peptide 是高度特异性的、CaMKII 的有效抑制剂，其 IC50值为 40 nM。
T82332	Gastric Inhibitory Polypeptide (6-30) amide (human)
	Gastric Inhibitory Polypeptide (6-30) amide (human) 为一种肠促胰岛素激素，主要应用于糖尿病研究领域。
T8986	ML198	Glucokinase	Metabolism
	ML198 是葡萄糖脑苷脂酶激活剂(EC50:0.4 μM)。它不会抑制该酶的作用，且能促进其易位至溶酶体，可用于研究戈谢病。
T9231	Mbx2329	Antiviral	Immunology/Inflammation
	MBX2329 是一种流感病毒抑制剂，能特异性地抑制血凝素介导的病毒进入，HIV/HA(H5) 的 IC90值为8.6 μM。它能够有效地抑制多种甲型流感病毒。
T1753	D-64131	Microtubule Associated	Cytoskeletal Signaling
	D64131 是一种微管蛋白聚合抑制剂，IC50 值为 0.53 μM。它具有抗丝分裂活性，可用于癌症研究。
T83696	Gastric Inhibitory Peptide 1 (3-42) (human) TFA Glucose-dependent Insulinotropic Polypeptide 3-42,GIP-1 (3-42)
	胃抑制肽1(GIP-1) (3-42)是肠促胰岛素激素GIP的一个肽段，同时也是GIP受体的拮抗剂。它通过血清二肽基肽酶4(DDP-4)从GIP中形成。GIP-1 (3-42) (100 nM)在减少BRIN-BD11胰腺细胞的胰岛素分泌方面起作用。在以25 nmol/kg剂量给药的ob/ob糖尿病小鼠模型中，它能增加血浆葡萄糖水平并降低血浆胰岛素水平。
T26127	R-PEP 27 Renin inhibitory peptide, R-pep-27,Pro-his-pro-phe-his-statine-ile-phe-NH2
	R-PEP 27 is an inhibitor of potent renin, decreased plasma angiotensin II, and blood pressure in normal volunteers.
T9963	MPT0B390	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	MPT0B390 是 HDAC 抑制剂和 TIMP3 诱导剂，可抑制肿瘤生长、转移和血管生成。
T11917	Lys-SMCC-DM1 Lys-Nε-MCC-DM1	Microtubule Associated	Cytoskeletal Signaling
	DM1 是一种微管蛋白抑制剂。 Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) 是 DM1 的活性代谢物。
T37588	GIP (1-30) amide, porcine
	This GIP fragment has potent insulinotropic activity in the isolated, perfused rat pancreas but greatly reduced somatostatinotropic activity in the isolated perfused rat stomach. The site responsible for insulinotropic activity apparently lies between residues 19 and 30 of GIP.
TP2054L	Calcineurin Autoinhibitory Peptide acetate	Phosphatase	Metabolism
	Calcineurin Autoinhibitory Peptide acetate 是一种选择性的钙调磷酸酶抑制剂 (IC50 ~ 10 μM)。它可用于保护神经元免受兴奋性神经元死亡。
T75864	Calcineurin autoinhibitory peptide TFA
	Calcineurin autoinhibitory peptide TFA 为选择性Ca2+/钙调蛋白依赖性蛋白磷酸酶（钙调神经磷酸酶）抑制剂，IC50约为10 μM。该化合物能够保护神经元不受兴奋性神经元死亡影响。
TP2054	Calcineurin Autoinhibitory Peptide
	Selective inhibitor of Ca2+-calmodulin-dependent protein phosphatase (calcineurin) (IC50 ~ 10 μM). Does not inhibit PP1, PP2A or CaM kinase II (IC50 > 100 mM).
T40335	AChE-IN-3	NO Synthase; AChE	Immunology/Inflammation; Neuroscience
	AChE-IN-3 对 AChE 有抑制作用，对 NO 抑制作用较强，其 EC50 为 0.57 μM。
T40823	NCGC00029283	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	NCGC00029283 is a potent inhibitor of Werner syndrome helicase-nuclease (WRN), displaying inhibitory activity against WRN helicase with an IC 50 value of 2.3 μM. Additionally, it exhibits inhibitory effects on Bloom syndrome protein helicase (BLM) and Fanconi anemia group J protein helicase (FANCJ) with IC 50 values of 12.5 μM and 3.4 μM, respectively.
T28904	T521 T 521	PLK	Cell Cycle/Checkpoint
	T521 是 Plk1 PBD 的选择性抑制剂，对 Plk2 和 Plk3 无抑制作用。
T21724L	Fas C-Terminal Tripeptide Acetate Fas C-Terminal Tripeptide Acetate (189109-90-8 free base)	Others; Fatty Acid Synthase	Metabolism; Others
	Fas C-Terminal Tripeptide Acetate 显示出对 Fas/FAP-1 结合的抑制活性。
T22932L	LPYFD-NH2 acetate LPYFD-NH2 acetate (700361-48-4 free base)	Beta Amyloid	Neuroscience
	LPYFD-NH2 acetate 对 Abeta(1-42) 的聚集有一定的抑制作用。
T77347	2-Amino-6-bromopyridine
	2-Amino-6-bromopyridine 对HIV-68蛋白酶具有抑制作用。
T29096	Vapitadine dihydrochloride Vapitadine 2HCl,R129160,R-129160 2HCl,Vapitadine HCl,R 129160 2HCl,R-129160,R 129160,R129160 2HCl	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Vapitadine dihydrochloride(R-129160 2HCl) 是一种新型强效且具有选择性和非镇静性的化合物，对组胺 H1 具有抑制作用。
T23201	PSB 1115	Adenosine Receptor	GPCR/G Protein; Neuroscience
	PSB 1115 是一种 A2B 受体拮抗剂，可以抵消 NECA 的抑制作用。
T24588	Palatrigine BW-A 256C,BW A256C	Adrenergic Receptor; Angiotensin-converting Enzyme (ACE)	GPCR/G Protein; Metabolism; Neuroscience
	Palatrigine (BW-A 256C) 是一种具有血管紧张素转换酶抑制和β肾上腺素受体阻断特性的化合物。

化合物

Ras Inhibitory Peptide acetate

Cat.No: T37422L

Synonym: Ras Inhibitory Peptide acetate(159088-48-9 Free base)

Target: Ras

Dynamin inhibitory peptide Acetate

Cat.No: T21798L

Synonym: Dynamin inhibitory peptide Acetate(251634-21-6 Free base)

Target: GTPase

IKKγ NBD Inhibitory Peptide acetate

Cat.No: TP1615L

Synonym: IKKγ NBD Inhibitory Peptide acetate(372146-18-4 free base)

Target: NF-κB

Dynamin inhibitory peptide, myristoylated acetate

Cat.No: TP1907L1

Synonym: Dynamin inhibitory peptide, myristoylated acetate(251634-22-7 free base)

Target: Dynamin

Autocamtide-2-related inhibitory peptide

Cat.No: TP2310

Target: CaMK, Autophagy

CaM kinase II inhibitor TFA salt

Cat.No: TP1216

Synonym: Autocamtide-2-related inhibitory peptide (TFA)

Target: CaMK

Autocamtide-2-related inhibitory peptide, myristoylated acetate(201422-04-0 free base)

Cat.No: TP1921L1

Target: CaMK, Autophagy

Ras Inhibitory Peptide

Cat.No: T37422

IKKγ NBD Inhibitory Peptide

Cat.No: TP1615

DynaMin inhibitory peptide, myristoylated

Cat.No: TP1907

Cdk2/Cyclin Inhibitory Peptide I

Cat.No: TP2192

Target: Others

Renin inhibitory peptide

Cat.No: TP2351

Synonym: Pro-his-pro-phe-his-phe-phe-val-tyr-lys

Acetyl Gastric Inhibitory Peptide (human) TFA

Cat.No: T78543

Synonym: Human N-acetyl GIP TFA

Renin inhibitory peptide, statine

Cat.No: TP2351L

Synonym: SCRIP,Iva-his-pro-phe-his-sta-leu-phe-NH2

Dynamin inhibitory peptide, myristoylated (control)

Cat.No: TP2039

Gastric Inhibitory Peptide, porcine

Cat.No: T76309

AC3-I, myristoylated

Cat.No: T80269

Synonym: Autocamtide-3 Derived Inhibitory Peptide

Target: CaMK

Dynamin inhibitory peptide TFA

Cat.No: T75796

GIP (3-42), human

Cat.No: T37589

Synonym: Gastric Inhibitory Polypeptide (3-42) (human)

Target: IGF-1R

Acetyl Gastric Inhibitory Peptide (human)

Cat.No: T76310

Cdk2/Cyclin Inhibitory Peptide II

Cat.No: T76377

IKKγ NBD Inhibitory Peptide TFA

Cat.No: T76024

TREM-1 inhibitory peptide M3

Cat.No: T80954

Gastric Inhibitory Polypeptide (1-30), porcine

Cat.No: T76308

[Tyr0] Gastric Inhibitory Peptide (23-42), human

Cat.No: T76307

Autocamtide-2-related inhibitory peptide TFA

Cat.No: T75736

Gastric Inhibitory Peptide (1-42) (porcine) TFA

Cat.No: T83694

Synonym: GIP (1-42),Glucose-dependent Insulinotropic Polypeptide (1-42)

Gastric Inhibitory Peptide (22-51) (human) TFA

Cat.No: T83710

Synonym: GIP (22-51),Glucose-dependent Insulinotropic Peptide (22-51)

Autocamtide-2-related inhibitory peptide, myristoylated TFA

Cat.No: T75737

Gastric Inhibitory Polypeptide (6-30) amide (human)

Cat.No: T82332

Cat.No: T8986

Target: Glucokinase

Cat.No: T9231

Target: Antiviral

Cat.No: T1753

Target: Microtubule Associated

Gastric Inhibitory Peptide 1 (3-42) (human) TFA

Cat.No: T83696

Synonym: Glucose-dependent Insulinotropic Polypeptide 3-42,GIP-1 (3-42)

Cat.No: T26127

Synonym: Renin inhibitory peptide, R-pep-27,Pro-his-pro-phe-his-statine-ile-phe-NH2

Cat.No: T9963

Target: HDAC

Cat.No: T11917

Synonym: Lys-Nε-MCC-DM1

Target: Microtubule Associated

GIP (1-30) amide, porcine

Cat.No: T37588

Calcineurin Autoinhibitory Peptide acetate

Cat.No: TP2054L

Target: Phosphatase

Calcineurin autoinhibitory peptide TFA

Cat.No: T75864

Calcineurin Autoinhibitory Peptide

Cat.No: TP2054

Cat.No: T40335

Target: NO Synthase, AChE

Cat.No: T40823

Target: DNA/RNA Synthesis

Cat.No: T28904

Synonym: T 521

Target: PLK

Fas C-Terminal Tripeptide Acetate

Cat.No: T21724L

Synonym: Fas C-Terminal Tripeptide Acetate (189109-90-8 free base)

Target: Others, Fatty Acid Synthase

LPYFD-NH2 acetate

Cat.No: T22932L

Synonym: LPYFD-NH2 acetate (700361-48-4 free base)

Target: Beta Amyloid

2-Amino-6-bromopyridine

Cat.No: T77347

Vapitadine dihydrochloride

Cat.No: T29096

Synonym: Vapitadine 2HCl,R129160,R-129160 2HCl,Vapitadine HCl,R 129160 2HCl,R-129160,R 129160,R129160 2HCl

Target: Histamine Receptor

Cat.No: T23201

Target: Adenosine Receptor

Cat.No: T24588

Synonym: BW-A 256C,BW A256C

Target: Adrenergic Receptor, Angiotensin-converting Enzyme (ACE)

Cat. No.	Product Name	Target	Signaling Pathways
T4811	D-Alanine D-α-Alanine,Ba 2776,(R)-Alanine,D-丙氨酸,(R)-2-Aminopropionic acid	Chloride channel; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism
	D-Alanine ((R)-Alanine) 是一种GlyR 和PMBA 的弱激动剂，其对GlyR 的EC50=9 mM。
T5796	Plantainoside D Isoplantamajoside,车前草苷D	RAAS; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Endocrinology/Hormones
	Plantainoside D (Isoplantamajoside) 可以抑制 ACE ，IC50=2.17 mM。Plantainoside D 也是IKK-β抑制剂。
TN5634	Aureusidin Auresudidin,金鱼草素,Auresidin	Antioxidant; Reactive Oxygen Species; Lipoxygenase	Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
	Aureusidin (Auresidin) 具有抗氧化和脂氧合酶抑制活性，具有抗炎作用。
TN1402	Arjungenin 阿江榄仁素,2ALPHA,19ALPHA,23-三羟基齐墩果酸	Antifection; Immunology/Inflammation related	Immunology/Inflammation; Microbiology/Virology
	Arjungenin, a triterpene derived from Terminalia arjuna, exhibits insect feeding-deterrent and growth inhibitory properties.
TN4510	(+)-Medioresinol Di-O-β-D-glucopyranoside (+)-Mediresinol Di-O-beta-D-glucopyranoside,(+)-Medioresinol Di-O-β-D-glucopyranoside	PDE	Metabolism
	(+)-Medioresinol Di-O-β-D-glucopyranoside 对环 AMP 磷酸二酯酶具有很强的抑制活性。
TN1031	Poricoic acid B 茯苓酸B,茯苓新酸 B	Others	Others
	Poricoic acid B 是提取自 Poria cocos 中，拥有抗肿瘤作用。
TN1799	Isorubrofusarin-6-O-β-gentiobioside Isorubrofusarin 10-gentiobioside	BACE; AChR	Neuroscience
	Isorubrofusarin-6-O-β-gentiobioside 来源于 Cassia obtusifolia Linn 种子，对 AChE 和 BACE1 具有良好的抑制活性。
TN1262	3-Feruloylquinic acid 3-O-阿魏酰奎尼酸,3-O-Feruloylquinic acid	Proteasome; Antifection	Microbiology/Virology; Proteases/Proteasome; Ubiquitination
	3-O-Feruloylquinic acid is a protease inhibitor, it exerts moderate inhibitory effect against AIV (H5N1) in vitro.
TN1427	Baicalin methyl ester	Anti-infection	Microbiology/Virology
	Baicalin methyl ester 是黄芩苷根的一种成分。
T8024	3-Indoleacetonitrile	Others; Endogenous Metabolite	Metabolism; Others
	3-Indoleacetonitrile 是内源性代谢产物的一种。
T8283	(+)-Bornyl Acetate Bornyl acetate,1-乙酸冰片酯,(+)-乙酸龙脑酯	Others	Others
	(+)-Bornyl Acetate 存在于 Pichtae 精油 (西伯利亚冷杉针油) 中。它能够显著抑制拟南芥幼苗根系生长。
TN2130	Manghaslin 槲皮素-3-O-芸香糖-(1→2)-O-鼠李糖苷,Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside	AChE; Glucosidase	Metabolism; Neuroscience
	Manghaslin (Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside) 是具有抗炎活性的黄酮苷，对 AChE 具有抑制活性，IC50=94.92 µM。
TN1256	3-O-Acetyl-16α-hydroxytrametenolic acid 3-O-乙酰基-16Α-羟基-氢化松苓酸,3-O-Acetyl-16 alpha-hydroxytrametenolic acid	Immunology/Inflammation related	Immunology/Inflammation
	3-O-Acetyl-16α-hydroxytrametenolic acid 是茯苓中的一种萜类物质，具有抗氧化、抗癌作用。
TQ0249	Alisol G 泽泻醇 G,25-脱水泽泻醇A,25-Anhydroalisol A,Alisol-G	hCE	Metabolism
	Alisol G (25-Anhydroalisol A) 是从泽泻 Rhizoma Alismatis 中分离出来的，具有 hCE2 抑制作用。
TN1037	Groenlandicine	Topoisomerase	DNA Damage/DNA Repair
	Groenlandicine 是来自黄连的一种原小檗碱生物碱，能诱导拓扑异构酶 I 介导的 DNA 裂解。它对人类重组醛糖还原酶(HRAR)具有中度的抑制作用，IC50值为 154.2 μM。
T6S0078	Oxypeucedanin hydrate Prangolarin Hydrate,水合氧化前胡素	Antioxidant	oxidation-reduction
	Oxypeucedanin hydrate (Prangolarin Hydrate) 是一种分离自D. anethifolia 中的天然香豆素化合物，存在于几种植物中，具有抗感染和抗真菌活性。
T2846	Isoimperatorin	Antibacterial; AChE	Microbiology/Virology; Neuroscience
	Isoimperatorin 是 Angelica dahurica 根的甲醇提取物，是一种抗炎剂，有效抑制乙酰胆碱酯酶，IC50为 74.6 μM。
T6S2122	Ginkgolic Acid (C13:0) 6-Tridecylsalicylic acid,Ginkgolic acid (13:0),Ginkgoneolic Acid,银杏酸C13:0,Ginkgolic acid C13:0	Antibacterial; Glucosidase	Metabolism; Microbiology/Virology
	Ginkgolic Acid (C13:0) (6-Tridecylsalicylic acid) 是一种天然防龋药，有抑菌活性。
TN1455	Bryodulcosigenin	Immunology/Inflammation related	Immunology/Inflammation
	Bryodulcosigenin 是一种 Bryoniadioica 根的提取物，具有抗炎活性。
T3803	Specnuezhenide 特女贞苷,Nuzhenide,Nuezhenide	Others; NF-κB; Wnt/beta-catenin	Cytoskeletal Signaling; NF-κB; Others; Stem Cells
	Specnuezhenide (Nuezhenide) 是分离自女贞子的果实中。它可抑制 NF-κB 和 wnt/β-catenin 信号传导，进而抑制 IL-1β 诱导的软骨细胞炎症。它可在骨关节炎 (OA) 大鼠模型中发挥抗炎作用。
T2S1814	p-Hydroxybenzaldehyde 4-Formylphenol,4-羟基苯甲醛;对羟基苯甲醛,4-hydroxybenzaldehyde,对羟基苯甲醛,p-Oxybenzaldehyde	Transaminase; GABA Receptor; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism; Neuroscience
	p-Hydroxybenzaldehyde (p-Oxybenzaldehyde) 是从天麻中提取的一种天然产物，对 GABA 转氨酶有抑制作用，有助于抗癫痫和抗惊厥活性。
T8213	Isolinderalactone	NOS; STAT	Immunology/Inflammation; JAK/STAT signaling; Stem Cells
	Isolinderalactone 具有抗炎和抗癌能力，具有中等的 iNOS 抑制活性，IC50 值为 0.30 uM。
T2S0765	Epibetulinic acid	NO Synthase; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Epibetulinic acid 对细菌内毒素刺激的小鼠巨噬细胞 (RAW 264.7) 中 NO 和前列腺素 E(2) 的产生具有有效的抑制作用，IC50分别为 0.7 和 0.6 μM，具有抗炎活性。
TN1028	Militarine	Others	Others
	Militarine 是一种糖苷化合物，分离自 Bletilla striata，能够抑制植物生长。
TN1002	Blumeatin	ROS	Immunology/Inflammation
	Blumeatin 是从Blumea balsamiferaDC 中分离得到，对 CCl4 和硫代乙酰胺 (TAA) 所致的肝损伤表现出保护活性。
T4S0051	Coptisine sulfate	Indoleamine 2,3-Dioxygenase (IDO)	Metabolism
	Coptisine Sulfate 是一种从黄连中分离到的生物碱，是非竞争性的IDO 抑制剂，Ki=为 5.8 μM，IC50=6.3 μM。
TN1073	Nuezhenidic acid 女贞子酸,女贞酸	Influenza Virus	Microbiology/Virology
	Nuezhenidic acid 是分离自Ligustrum lucidum 中，具有抑制流感病毒 A 作用。
TN2159	Robustine 大叶桉亭,8-羟基白鲜碱,4-甲氧基呋喃并[2,3-B]喹啉-8-醇	PDE	Metabolism
	Robustine 是一种从 Dictamnus albus 获得的呋喃喹啉生物碱，在体外对人磷酸二酯酶 5 (hPDE5A) 具有抑制作用。
TN2003	Obtucarbamate A 4-甲基苯-1,3-二氨基甲酸二甲酯,钝叶扁柏氨基甲酸酯 A,钝叶扁柏氨基甲酸酯A	NO Synthase	Immunology/Inflammation
	Obtucarbamate A 分离自Disporum cantoniense 中，具有镇咳作用。
TN2027	Oxysanguinarine 8-Oxosanguinarine,氧化血根碱,Hydroxysanguinarine	Parasite	Microbiology/Virology
	Oxysanguinarine (Hydroxysanguinarine) 是一种来自Meconopsis simplicifolia 的小檗生物碱，具有抗疟和抗血小板聚集活性，对登革热病毒具有潜在的抑制作用。
TN1091	Dehydronuciferine	AChE	Neuroscience
	Dehydronuciferine 是一种乙酰胆碱酯酶抑制剂，其 IC50=25 μg/mL，是从 Nelumbo nucifera Gaertn 的叶子中分离得到。
T40388	Methyl 5-hydroxypyridine-2-carboxylate	Others	Others
	Methyl 5-hydroxypyridine-2-carboxylate 是存在于 Mahonia fortune 茎中的一种酚酸，在体外表现出 NO 抑制活性。
T3329	4',7-Dimethoxyisoflavone 4',7-二甲氧基异黄酮,Dimethoxydaidzein,Daidzein dimethyl ether	Endogenous Metabolite; Antifungal	Metabolism; Microbiology/Virology
	4',7-Dimethoxyisoflavone (Daidzein dimethyl ether) 是从阔荚合欢中分离的黄酮类化合物，有抗真菌作用，可抑制大鼠前列腺睾酮5α-还原酶。
T11012	Dextran Dextran 40,葡聚糖	Platelet aggregation	Others
	Dextran 对血小板聚集和凝血因子有抑制作用，用作增加血浆容量的药剂。
T3781	Jujuboside B 酸枣仁皂苷 B,酸枣仁皂苷B	Others	Others
	Jujuboside B 是一种提取自Zizyphus jujuba 中的活性成分，对血小板聚集具有抑制作用。
T4931	Dihydroxyfumaric acid hydrate	Others; Endogenous Metabolite	Metabolism; Others
	Dihydroxyfumaric acid hydrate 是内源性代谢产物的一种。
T8188	Podophyllotoxone	Others; Microtubule Associated	Cytoskeletal Signaling; Others
	Podophyllotoxone 是从八角莲根中分离得到的一种天然产物，能抑制微管蛋白聚合，具有抗癌活性。
TN1111	Arnidiol	Immunology/Inflammation related	Immunology/Inflammation
	Arnidiol 是一种五环三萜烯，从Barleria Longiflora LinnF. 中提取得到。
T3S1089	Phillygenin Epipinoresinol methyl ether,(+)-Phillygenin,Phillygenol,Sylvatesmin,Forsythigenol,连翘脂素	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Phillygenin (Sylvatesmin) 是一种连翘的活性组分，有很多的药用价值，包括抗氧化剂，降血脂，抑制低密度脂蛋白氧化。
T5S1408	Pteryxin 北美芹素,(+)-Pteryxin	Others; AChE	Neuroscience; Others
	Pteryxin ((+)-Pteryxin) 是一种白花前胡叶中的香豆素，是一种有效的丁酰胆碱酯酶(BChE)抑制剂，IC50=12.96 μg/ml，具有抗肥胖作用。
TN1153	Polyporenic acid C 猪苓酸C,聚孔酸C	Apoptosis; PARP; Caspase; PI3K	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Polyporenic acid C 是从茯苓中分离出的一种羊毛甾烷型三萜，可通过死亡受体介导的凋亡途径诱导细胞凋亡，有用于肺癌的研究潜力。
T2S0731	Trilobatin 三叶苷,三叶甙,P-Phlorizin	Amylase	Metabolism
	Trilobatin (P-Phlorizin) 是源自Lithocarpus polystachyusRehd 的甜味剂，是一种HIV-1抑制剂，靶向 Gp41 包膜蛋白，具有神经保护作用。它还是SGLT1/2抑制剂，可选择性诱导人肝母细胞瘤细胞增殖。
TN1466	Canthin-6-one NSC 103003	Antifungal	Microbiology/Virology
	Canthin-6-one(NSC 103003) 是一种从 Allium neapolitanum 分离出来的生物碱，具有抗菌活性，对结核分枝杆菌具有抑制作用。
TN5757	p-Hydroxybenzaldehyde glucoside 4-formylphenyl b-d-glucopyranoside,Gastrodin Impurity
	p-Hydroxybenzaldehyde glucoside (4-formylphenyl b-d-glucopyranoside) 是抑制天麻素衍生物，具有镇痛活性，可以用于研究神经源性疼痛。
T12142	N-Caffeoyl O-methyltyramine	Glucosidase	Metabolism
	N-Caffeoyl O-methyltyramine 是一种生物碱，分离自Cuscuta reflexa，能够较大程度抑制α-葡萄糖苷酶的活性(IC50:103.58 μM)。
T13130	Terphenyllin	Glucosidase	Metabolism
	Terphenyllin 是一种天然对三联苯代谢物，分离自珊瑚源真菌念珠菌，能够显著抑制α-葡萄糖苷酶的活性。
TN1656	Ganoderenic acid A 灵芝烯酸A,灵芝烯酸 A	Others	Others
	Ganoderenic acid A 是三萜类化合物。它对 CCl4 诱导的肝损伤具有保护作用。它是β-葡萄糖醛酸酶抑制剂。
TN2277	Torachrysone-8-O-b-D-glucoside 芦荟大黄素 8-葡萄糖甙,Torachrysone 8-O-glucoside	Antifection	Microbiology/Virology
	Torachrysone-8-O-b-D-glucoside 可从 Polygonum multiflorum 分离得到。它对 DPCs(真皮乳头细胞)的增殖具有促进作用。
T6407	β-Lapachone 3,4-二氢-2,2-二甲基-2H-萘并[1,2-B]吡喃-5,6-二酮,Beta-Lapachone,NSC-26326,SL-11001,ARQ-501	IDO; Apoptosis; Topoisomerase; Autophagy	Apoptosis; Autophagy; DNA Damage/DNA Repair; Metabolism
	β-Lapachone (ARQ-501) 是一种萘醌类天然产物，是拓扑异构酶 I 抑制剂，通过抑制细胞周期进程来诱导细胞凋亡。
T4S0217	HOMOPLANTAGININ	TNF; NF-κB	Apoptosis; NF-κB
	Homoplantaginin 是来自中药荔枝草的一种类黄酮，具有抗炎和抗氧化活性。
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天然产物

Cat.No: T4811

Synonym: D-α-Alanine,Ba 2776,(R)-Alanine,D-丙氨酸,(R)-2-Aminopropionic acid

Target: Chloride channel, Endogenous Metabolite

Plantainoside D

Cat.No: T5796

Synonym: Isoplantamajoside,车前草苷D

Target: RAAS, PKC

Cat.No: TN5634

Synonym: Auresudidin,金鱼草素,Auresidin

Target: Antioxidant, Reactive Oxygen Species, Lipoxygenase

Cat.No: TN1402

Synonym: 阿江榄仁素,2ALPHA,19ALPHA,23-三羟基齐墩果酸

Target: Antifection, Immunology/Inflammation related

(+)-Medioresinol Di-O-β-D-glucopyranoside

Cat.No: TN4510

Synonym: (+)-Mediresinol Di-O-beta-D-glucopyranoside,(+)-Medioresinol Di-O-β-D-glucopyranoside

Target: PDE

Poricoic acid B

Cat.No: TN1031

Synonym: 茯苓酸B,茯苓新酸 B

Target: Others

Isorubrofusarin-6-O-β-gentiobioside

Cat.No: TN1799

Synonym: Isorubrofusarin 10-gentiobioside

Target: BACE, AChR

3-Feruloylquinic acid

Cat.No: TN1262

Synonym: 3-O-阿魏酰奎尼酸,3-O-Feruloylquinic acid

Target: Proteasome, Antifection

Baicalin methyl ester

Cat.No: TN1427

Target: Anti-infection

3-Indoleacetonitrile

Cat.No: T8024

Target: Others, Endogenous Metabolite

(+)-Bornyl Acetate

Cat.No: T8283

Synonym: Bornyl acetate,1-乙酸冰片酯,(+)-乙酸龙脑酯

Target: Others

Cat.No: TN2130

Synonym: 槲皮素-3-O-芸香糖-(1→2)-O-鼠李糖苷,Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside

Target: AChE, Glucosidase

3-O-Acetyl-16α-hydroxytrametenolic acid

Cat.No: TN1256

Synonym: 3-O-乙酰基-16Α-羟基-氢化松苓酸,3-O-Acetyl-16 alpha-hydroxytrametenolic acid

Target: Immunology/Inflammation related

Cat.No: TQ0249

Synonym: 泽泻醇 G,25-脱水泽泻醇A,25-Anhydroalisol A,Alisol-G

Target: hCE

Cat.No: TN1037

Target: Topoisomerase

Oxypeucedanin hydrate

Cat.No: T6S0078

Synonym: Prangolarin Hydrate,水合氧化前胡素

Target: Antioxidant

Cat.No: T2846

Target: Antibacterial, AChE

Ginkgolic Acid (C13:0)

Cat.No: T6S2122

Synonym: 6-Tridecylsalicylic acid,Ginkgolic acid (13:0),Ginkgoneolic Acid,银杏酸C13:0,Ginkgolic acid C13:0

Target: Antibacterial, Glucosidase

Bryodulcosigenin

Cat.No: TN1455

Target: Immunology/Inflammation related

Cat.No: T3803

Synonym: 特女贞苷,Nuzhenide,Nuezhenide

Target: Others, NF-κB, Wnt/beta-catenin

p-Hydroxybenzaldehyde

Cat.No: T2S1814

Synonym: 4-Formylphenol,4-羟基苯甲醛;对羟基苯甲醛,4-hydroxybenzaldehyde,对羟基苯甲醛,p-Oxybenzaldehyde

Target: Transaminase, GABA Receptor, Endogenous Metabolite

Isolinderalactone

Cat.No: T8213

Target: NOS, STAT

Epibetulinic acid

Cat.No: T2S0765

Target: NO Synthase, Prostaglandin Receptor

Cat.No: TN1028

Target: Others

Cat.No: TN1002

Target: ROS

Coptisine sulfate

Cat.No: T4S0051

Target: Indoleamine 2,3-Dioxygenase (IDO)

Nuezhenidic acid

Cat.No: TN1073

Synonym: 女贞子酸,女贞酸

Target: Influenza Virus

Cat.No: TN2159

Synonym: 大叶桉亭,8-羟基白鲜碱,4-甲氧基呋喃并[2,3-B]喹啉-8-醇

Target: PDE

Obtucarbamate A

Cat.No: TN2003

Synonym: 4-甲基苯-1,3-二氨基甲酸二甲酯,钝叶扁柏氨基甲酸酯 A,钝叶扁柏氨基甲酸酯A

Target: NO Synthase

Oxysanguinarine

Cat.No: TN2027

Synonym: 8-Oxosanguinarine,氧化血根碱,Hydroxysanguinarine

Target: Parasite

Dehydronuciferine

Cat.No: TN1091

Target: AChE

Methyl 5-hydroxypyridine-2-carboxylate

Cat.No: T40388

Target: Others

4',7-Dimethoxyisoflavone

Cat.No: T3329

Synonym: 4',7-二甲氧基异黄酮,Dimethoxydaidzein,Daidzein dimethyl ether

Target: Endogenous Metabolite, Antifungal

Cat.No: T11012

Synonym: Dextran 40,葡聚糖

Target: Platelet aggregation

Cat.No: T3781

Synonym: 酸枣仁皂苷 B,酸枣仁皂苷B

Target: Others

Dihydroxyfumaric acid hydrate

Cat.No: T4931

Target: Others, Endogenous Metabolite

Podophyllotoxone

Cat.No: T8188

Target: Others, Microtubule Associated

Cat.No: TN1111

Target: Immunology/Inflammation related

Cat.No: T3S1089

Synonym: Epipinoresinol methyl ether,(+)-Phillygenin,Phillygenol,Sylvatesmin,Forsythigenol,连翘脂素

Target: Reactive Oxygen Species

Cat.No: T5S1408

Synonym: 北美芹素,(+)-Pteryxin

Target: Others, AChE

Polyporenic acid C

Cat.No: TN1153

Synonym: 猪苓酸C,聚孔酸C

Target: Apoptosis, PARP, Caspase, PI3K

Cat.No: T2S0731

Synonym: 三叶苷,三叶甙,P-Phlorizin

Target: Amylase

Cat.No: TN1466

Synonym: NSC 103003

Target: Antifungal

p-Hydroxybenzaldehyde glucoside

Cat.No: TN5757

Synonym: 4-formylphenyl b-d-glucopyranoside,Gastrodin Impurity

N-Caffeoyl O-methyltyramine

Cat.No: T12142

Target: Glucosidase

Cat.No: T13130

Target: Glucosidase

Ganoderenic acid A

Cat.No: TN1656

Synonym: 灵芝烯酸A,灵芝烯酸 A

Target: Others

Torachrysone-8-O-b-D-glucoside

Cat.No: TN2277

Synonym: 芦荟大黄素 8-葡萄糖甙,Torachrysone 8-O-glucoside

Target: Antifection

Cat.No: T6407

Synonym: 3,4-二氢-2,2-二甲基-2H-萘并[1,2-B]吡喃-5,6-二酮,Beta-Lapachone,NSC-26326,SL-11001,ARQ-501

Target: IDO, Apoptosis, Topoisomerase, Autophagy

HOMOPLANTAGININ

Cat.No: T4S0217

Target: TNF, NF-κB

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