首页工具

登录

搜索结果

Search Results for " chemotherapy "

97

抑制剂 & 化合物

17

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T2747	Endothall	Others	Others
	Endothall 是一种有效的蛋白磷酸酶 2A (PP2A) 抑制剂，对 PP2A 和 PP1 具有抑制作用， IC50 分别为 90 nM 和 5 µM。Endothall 具有抗癌活性，可用于癌症化疗，可用作除草剂。
T21876	DC_AC50	Apoptosis; Others	Apoptosis; Others
	DC_AC50 是一种 Atox 和 CCS 的双抑制剂，是一种抑制细胞内铜伴侣作为减少/预防获得性化疗耐药性的手段。它与 Atox1 和 CCS 结合并减少癌细胞增殖和肿瘤生长。
T22746	Tesmilifene fumarate DPPE fumarate	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Tesmilifene fumarate (DPPE fumarate) 是一种 H1C 受体拮抗剂，可增强化疗的细胞毒性且保护正常细胞。
T9271	RAD51-IN-1	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	RAD51-IN-1 是 B02 的衍生物，是一种RAD51的有效抑制剂，可研究癌症。
T1564	Cisplatin cis-Diaminodichloroplatinum,CDDP,顺铂	DNA Alkylator/Crosslinker; Ferroptosis; DNA/RNA Synthesis; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Cisplatin (CDDP) 是一种 DNA 交联剂。Cisplatin 具有抗肿瘤活性，能够通过在癌细胞中形成 DNA 加合物来抑制 DNA 合成。Cisplatin 还可激活铁死亡并诱导自噬。
T1414	Sodium 2-mercaptoethanesulfonate Mitexan,美司那,美司钠,Uromitexan,Mesna,Mesnum,Mesnex	Others	Others
	Sodium 2-mercaptoethanesulfonate (Uromitexan) 是一种抗氧化剂，具有细胞保护作用。它可用于减轻由环磷酰胺引起的出血性膀胱炎。它广泛用作抗化学疗法毒性的全身保护剂。
T1528	Azasetron hydrochloride Y-25130 hydrochloride,Y-25130 HCl,盐酸阿扎司琼,Azasetron HCl	5-HT Receptor	GPCR/G Protein; Neuroscience
	Azasetron hydrochloride (Y-25130 HCl) 是一种苯甲酰胺的衍生物，是有效的、选择性的5-HT3受体拮抗剂，可用于化疗引起的恶心呕吐研究。
T2047	AG-1478 AG1478,NSC 693255,Tyrphostin AG-1478	EGFR; HCV Protease; Influenza Virus; HER; PDGFR	Angiogenesis; JAK/STAT signaling; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors
	AG-1478 (NSC-693255) 是一种选择性 EGFR 酪氨酸激酶抑制剂，IC50为 3 nM。它对 HCV 和脑心肌炎病毒有抗病毒作用。
T1478	Ondansetron hydrochloride dihydrate 盐酸昂丹司琼,SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride	5-HT Receptor	GPCR/G Protein; Neuroscience
	Ondansetron hydrochloride dihydrate (GR 38032) 是5- HT3受体拮抗剂，可治疗化疗后的恶心和呕吐，有抗焦虑和抗精神病作用。
T1790	Fosaprepitant dimeglumine 福沙匹坦二甲葡胺,L785298,福沙吡坦二甲葡胺,MK-0517,Fosaprepitant dimeglumine salt	Neurokinin receptor	GPCR/G Protein; Neuroscience
	Fosaprepitant dimeglumine (MK-0517) 是 Aprepitant 的前药。它是一种神经激肽 1 受体拮抗剂，可用于预防化疗引起的恶心呕吐。
T16871	Semustine	DNA Alkylator/Crosslinker	DNA Damage/DNA Repair
	Semustine 是一种 DNA 烷化剂，是一种癌症化疗化合物，在接受辅助化疗的恶性黑色素瘤患者中具有肾毒性，可用于辅助治疗白血病。
T21899	Misonidazole SR-1354,SR1354,Ro 7-0582	GPX	oxidation-reduction
	Misonidazole 是一种缺氧肿瘤细胞放射增敏剂，具有抗菌活性。
T22313	Dolasetron Mesylate 多拉司琼甲磺酸盐,甲磺酸多拉司琼,Anzemet hydrate,MDL-73147EF	Others; 5-HT Receptor	GPCR/G Protein; Neuroscience; Others
	Dolasetron Mesylate (MDL-73147EF) 是 5-HT3 受体的拮抗剂，可用于治疗化疗后呕吐和恶心的研究。
T28187	Nonabine
	Nonabine 是一种具有强烈止吐作用的化合物，可用来预防与癌症化疗有关的恶心和呕吐。
T68068L	(R)-CJ 11974	Neurokinin receptor	GPCR/G Protein; Neuroscience

T24184	Itasetron DAU6215CL,UNII-00S0D0OEKR,U-98079A,U 98079A,DAU 6215CL	5-HT Receptor	GPCR/G Protein; Neuroscience
	Itasetron (U 98079A) 是一种5-羟色胺3受体拮抗剂，可用于预防大鼠与年龄有关的记忆缺陷。Itasetron 在癌症化疗和放疗动物模型中的止吐活性，可用于研究健忘症。
T4568	Dolasetron MDL-73147,多拉司琼	5-HT Receptor	GPCR/G Protein; Neuroscience
	Dolasetron (MDL-73147) 是一种血清素 5-HT3 受体拮抗剂，用于治疗化疗后的恶心和呕吐。
T10244	ACY-1083	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	ACY-1083 是一种选择性和脑穿透性 HDAC6 抑制剂 (IC50：3 nM)，可有效逆转化疗引起的周围神经病变。
T39024	PrNMI	Cannabinoid Receptor	GPCR/G Protein
	PrNMI is a highly effective and orally active agonist targeting the peripherally restricted cannabinoid 1 receptor (CB1R). It exhibits pronounced analgesic properties, efficiently suppressing both chemotherapy-induced peripheral neuropathy pain symptoms and cancer-induced bone pain.
T6616	Ondansetron hydrochloride SN 307,盐酸昂丹司琼,帕罗西汀杂质A,Ondansetron HCl,Emeset,GR 38032 HCl,NSC 665799,Zofran	5-HT Receptor	GPCR/G Protein; Neuroscience
	Ondansetron hydrochloride (Zofran) 是5-HT3受体的拮抗剂，可用作化疗后止吐剂。
T1755	LY2090314	GSK-3	PI3K/Akt/mTOR signaling; Stem Cells
	LY2090314 是GSK-3抑制剂，抑制 GSK-3α (IC50:1.5 nM) 和 GSK-3β (IC50:0.9 nM)。
T1042	Granisetron hydrochloride 盐酸格拉司琼,BRL 43694A,Granisetron HCl	5-HT Receptor	GPCR/G Protein; Neuroscience
	Granisetron hydrochloride (Granisetron HCl) 是一种5-HT3受体拮抗剂，可作为化疗后止吐剂。
T28935	TDRL-551	Others	Others
	TDRL-551 是一种新型有效的复制蛋白A (RPA) 抑制剂 (IC50=18 µM)，具有潜在的抗癌活性。TDRL-551 对 RPA-DNA 相互作用有抑制作用，提高以铂为基础的肺癌和卵巢癌化疗的疗效。
T0776	Phenothiazine ENT 38,吩噻嗪	Dopamine Receptor; Antibacterial; Antibiotic; Antifungal	GPCR/G Protein; Microbiology/Virology; Neuroscience
	Phenothiazine (ENT 38) 是一种抗生素，具有杀虫，抗菌，驱虫和杀真菌活性。它也可研究神经系统疾病。
T3716	Rolapitant 罗拉吡坦,SCH619734,罗拉匹坦	Neurokinin receptor	GPCR/G Protein; Neuroscience
	Rolapitant (SCH619734) 是一种高效选择性具有口服活性的神经激肽 1 受体抑制剂，Ki 值为0.66 nM。
T6127	Rucaparib Phosphate AG-014699 phosphate,PF-01367338,芦卡帕利,AG-014699,瑞卡帕布磷酸盐,PF-01367338 phosphate	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Rucaparib Phosphate (PF-01367338 phosphate) 是一种口服有效的PARP 蛋白抑制剂，对 PARP-1 的Ki 为 1.4 nM。它是六磷酸己糖脱氢酶 (H6PD) 抑制剂，有用于去势抵抗性前列腺癌 (CRPC) 的研究潜力。
T76788	Demcizumab OMP 21M18	Gamma-secretase	Neuroscience; Proteases/Proteasome; Stem Cells
	Demcizumab (OMP 21M18) 是一种抗 DLL4 单克隆抗体。Demcizumab 是一种有效的 Notch 通路抑制剂。Demcizumab 在多种癌症模型中无论使单独还联合化疗试剂使用都是有效的。
T2589	Dolasetron Mesylate hydrate Dalasetron Mesylate Hydrate,多拉司琼甲磺酸盐一水合物	5-HT Receptor	GPCR/G Protein; Neuroscience
	Dolasetron Mesylate hydrate (Dalasetron Mesylate Hydrate) 是一种选择性血清素受体拮抗剂，可竞争性阻断血清素对 5HT3 受体的作用，从而抑制化疗和放疗引起的恶心和呕吐。
T9955	EX-A5758	NOS	Immunology/Inflammation
	EX-A5758是一种新型推定的小分子 nNOS-NOS1 AP 抑制剂，可抑制炎症性伤害感受和化疗引起的神经性疼痛，并与紫杉醇协同降低肿瘤细胞活力
T4451	Estramustine phosphate sodium Ro 21-8837/001,Estramustine phosphate disodium,雌莫司汀磷酸钠	Apoptosis; Microtubule Associated	Apoptosis; Cytoskeletal Signaling
	Estramustine phosphate sodium (Ro 21-8837/001) 是雌二醇类似物，是一种具有口服活性抗微管化疗剂，通过与微管相关蛋白和微管蛋白结合而使微管解聚。它可诱导前列腺癌细胞凋亡，可研究前列腺癌。
T4684	ML241 hydrochloride	p97	Ubiquitination
	ML241 hydrochloride 是一种有效且选择性的 p97 ATPase 抑制剂，IC50值为 100 nM。
T15611	JH-RE-06	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	JH-RE-06是一种REV1-REV7互作抑制剂，IC50为0.78 μM，Kd 为0.42 μM。它靶向与 POLζ 的 REV7 亚基相互作用的 REV1，可改善化疗效果。它通过阻止诱变 POLζ 的募集来破坏诱变性跨损伤合成。
T2283	PX-12 2-[(1-甲基丙基)二硫代]-1H-咪唑,IV-2,PX12	Thioredoxin	Metabolism
	PX-12 (PX12) 是一种可逆的硫氧还蛋白-1(Trx-1)抑制剂，能够抑制 MCF-7 细胞(IC50:1.9 μM)和HT-29 细胞(IC50:2.9 μM)的生长。
T2265	Bimiralisib 5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine,PQR309,PI3K-IN-2	Others; PI3K; S6 Kinase; mTOR	MAPK; Others; PI3K/Akt/mTOR signaling
	Bimiralisib (PI3K-IN-2) 是一种有效的，可渗透脑的 mTOR/PI3K 抑制剂，是一种 mTORC1和 mTORC2抑制剂。它能够抑制 PI3Kα,PI3Kδ,PI3Kβ,PI3Kγ和 mTOR，IC50分别为 33 nM，451 nM，661 nM，708 nM 和 89 nM。
T3614	Inosine pranobex Groprinosin,Isoprinosine,异丙肌苷,Immunovir,Delimmun	IL Receptor; HIV Protease	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Inosine pranobex (Delimmun) 是一种免疫增强剂，它是一种广谱抗病毒剂，用于 HIV 感染。
T31977	GLYN NSC 137875,NSC137875,Glycidyl nitrate,NSC-137875
	GLYN, a nitric oxide donor, acts by enhancing the therapeutic efficacy of chemotherapy and radiotherapy.
T26283	TNP-351 Tnp 351
	Tnp 351 is a novel antifolate drug being assessed for chemotherapy of lung cancer.
T1120L	Dacarbazine hydrochloride Dacarbazine HCl
	Dacarbazine ( imidazole carboxamide) is a chemotherapy drug used to treat melanoma and Hodgkin's lymphoma.
T29486	7-Methotrexate 7-Mtx
	7-Methotrexate is used as a chemotherapy agent and immune system suppressant. It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and medical abortions.
T22393	Palonosetron RS25259,帕洛诺司琼,RS 25259 197	5-HT Receptor	GPCR/G Protein; Neuroscience
	Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
T29391	3'-Chloromethotrexate NSC 29631,NSC29631,SKI 23338,NSC-29631,AI3-50533
	3'-Chloromethotrexate is a chemotherapy agent and immune system suppressant. It can be used to treat cancer, autoimmune diseases, ectopic pregnancy, and medical abortions.
T22340	Granisetron Sustol,Granisetronum,格拉司琼,Sancuso,Kevatril	5-HT Receptor	GPCR/G Protein; Neuroscience
	Granisetron, a serotonin receptor (5HT-3 selective) antagonist, is used as an antinauseant and antiemetic for cancer chemotherapy.
T68274	QZ59S-SSS
	QZ59S-SSS acts as a potential inhibitor of human P-glycoprotein and may be used to improve the efficacy of cancer chemotherapy.
T70114	Paclitaxel Ceribate
	Paclitaxel Ceribate is a mitotic inhibitor used in cancer chemotherapy.
T25929	Pemetrexed tromethamine Pemetrexed ditromethamine dihydrate
	Pemetrexed tromethamine is a chemotherapy drug used for pleural mesothelioma and non-small cell lung cancer.
T30041	Amphoglucamine
	Amphoglucamine is used in the combined chemotherapy of viral diseases.
T13161	Tin-protoporphyrin IX 锡原卟啉IX,SnPPIX	Others	Others
	Tin-protoporphyrin IX is a potent inhibitor of Heme oxygenase-1 (HO-1). It sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice models.
T31837	FOLFIRI Regimen FOLFIRI
	FOLFIRI Regimen is a chemotherapy regimen consisting of leucovorin calcium (calcium folinate), 5-fluorouracil, and irinotecan used during the treatment of advanced-stage and metastatic colorectal cancer.
T71123	RG 12915
	RG 12915 is a potent, selective 5-HT3 receptor antagonist developed for the treatment of emesis and nausea associated with cancer chemotherapy.
T33326	Methotrexate-alpha glutamate Meapa-glu-glu
	Methotrexate-alpha glutamate is a chemotherapy agent and immune system suppressant. It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and medical abortions.

化合物

Cat.No: T2747

Target: Others

Cat.No: T21876

Target: Apoptosis, Others

Tesmilifene fumarate

Cat.No: T22746

Synonym: DPPE fumarate

Target: Histamine Receptor

Cat.No: T9271

Target: DNA/RNA Synthesis

Cat.No: T1564

Synonym: cis-Diaminodichloroplatinum,CDDP,顺铂

Target: DNA Alkylator/Crosslinker, Ferroptosis, DNA/RNA Synthesis, Autophagy

Sodium 2-mercaptoethanesulfonate

Cat.No: T1414

Synonym: Mitexan,美司那,美司钠,Uromitexan,Mesna,Mesnum,Mesnex

Target: Others

Azasetron hydrochloride

Cat.No: T1528

Synonym: Y-25130 hydrochloride,Y-25130 HCl,盐酸阿扎司琼,Azasetron HCl

Target: 5-HT Receptor

Cat.No: T2047

Synonym: AG1478,NSC 693255,Tyrphostin AG-1478

Target: EGFR, HCV Protease, Influenza Virus, HER, PDGFR

Ondansetron hydrochloride dihydrate

Cat.No: T1478

Synonym: 盐酸昂丹司琼,SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride

Target: 5-HT Receptor

Fosaprepitant dimeglumine

Cat.No: T1790

Synonym: 福沙匹坦二甲葡胺,L785298,福沙吡坦二甲葡胺,MK-0517,Fosaprepitant dimeglumine salt

Target: Neurokinin receptor

Cat.No: T16871

Target: DNA Alkylator/Crosslinker

Cat.No: T21899

Synonym: SR-1354,SR1354,Ro 7-0582

Target: GPX

Dolasetron Mesylate

Cat.No: T22313

Synonym: 多拉司琼甲磺酸盐,甲磺酸多拉司琼,Anzemet hydrate,MDL-73147EF

Target: Others, 5-HT Receptor

Cat.No: T28187

Cat.No: T68068L

Target: Neurokinin receptor

Cat.No: T24184

Synonym: DAU6215CL,UNII-00S0D0OEKR,U-98079A,U 98079A,DAU 6215CL

Target: 5-HT Receptor

Cat.No: T4568

Synonym: MDL-73147,多拉司琼

Target: 5-HT Receptor

Cat.No: T10244

Target: HDAC

Cat.No: T39024

Target: Cannabinoid Receptor

Ondansetron hydrochloride

Cat.No: T6616

Synonym: SN 307,盐酸昂丹司琼,帕罗西汀杂质A,Ondansetron HCl,Emeset,GR 38032 HCl,NSC 665799,Zofran

Target: 5-HT Receptor

Cat.No: T1755

Target: GSK-3

Granisetron hydrochloride

Cat.No: T1042

Synonym: 盐酸格拉司琼,BRL 43694A,Granisetron HCl

Target: 5-HT Receptor

Cat.No: T28935

Target: Others

Cat.No: T0776

Synonym: ENT 38,吩噻嗪

Target: Dopamine Receptor, Antibacterial, Antibiotic, Antifungal

Cat.No: T3716

Synonym: 罗拉吡坦,SCH619734,罗拉匹坦

Target: Neurokinin receptor

Rucaparib Phosphate

Cat.No: T6127

Synonym: AG-014699 phosphate,PF-01367338,芦卡帕利,AG-014699,瑞卡帕布磷酸盐,PF-01367338 phosphate

Target: PARP

Cat.No: T76788

Synonym: OMP 21M18

Target: Gamma-secretase

Dolasetron Mesylate hydrate

Cat.No: T2589

Synonym: Dalasetron Mesylate Hydrate,多拉司琼甲磺酸盐一水合物

Target: 5-HT Receptor

Cat.No: T9955

Target: NOS

Estramustine phosphate sodium

Cat.No: T4451

Synonym: Ro 21-8837/001,Estramustine phosphate disodium,雌莫司汀磷酸钠

Target: Apoptosis, Microtubule Associated

ML241 hydrochloride

Cat.No: T4684

Target: p97

Cat.No: T15611

Target: DNA/RNA Synthesis

Cat.No: T2283

Synonym: 2-[(1-甲基丙基)二硫代]-1H-咪唑,IV-2,PX12

Target: Thioredoxin

Cat.No: T2265

Synonym: 5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine,PQR309,PI3K-IN-2

Target: Others, PI3K, S6 Kinase, mTOR

Inosine pranobex

Cat.No: T3614

Synonym: Groprinosin,Isoprinosine,异丙肌苷,Immunovir,Delimmun

Target: IL Receptor, HIV Protease

Cat.No: T31977

Synonym: NSC 137875,NSC137875,Glycidyl nitrate,NSC-137875

Cat.No: T26283

Synonym: Tnp 351

Dacarbazine hydrochloride

Cat.No: T1120L

Synonym: Dacarbazine HCl

Cat.No: T29486

Synonym: 7-Mtx

Cat.No: T22393

Synonym: RS25259,帕洛诺司琼,RS 25259 197

Target: 5-HT Receptor

3'-Chloromethotrexate

Cat.No: T29391

Synonym: NSC 29631,NSC29631,SKI 23338,NSC-29631,AI3-50533

Cat.No: T22340

Synonym: Sustol,Granisetronum,格拉司琼,Sancuso,Kevatril

Target: 5-HT Receptor

Cat.No: T68274

Paclitaxel Ceribate

Cat.No: T70114

Pemetrexed tromethamine

Cat.No: T25929

Synonym: Pemetrexed ditromethamine dihydrate

Cat.No: T30041

Tin-protoporphyrin IX

Cat.No: T13161

Synonym: 锡原卟啉IX,SnPPIX

Target: Others

FOLFIRI Regimen

Cat.No: T31837

Synonym: FOLFIRI

Cat.No: T71123

Methotrexate-alpha glutamate

Cat.No: T33326

Synonym: Meapa-glu-glu

Cat. No.	Product Name	Target	Signaling Pathways
T2217	Cephalomannine Baccatin III,三尖杉宁碱	Microtubule Associated	Cytoskeletal Signaling
	Cephalomannine (Baccatin III) 是一种从云南红豆杉中提取的紫杉醇衍生物，具有抗肿瘤活性，可用于癌症研究。
T21936	M50054 2,2′-亚甲基双(1,3-环己二酮)	Caspase	Apoptosis; Proteases/Proteasome
	M50054 是一种有效的细胞凋亡抑制剂，可用于研究抗 Fas 抗体引起的肝炎和化疗引起的脱发。它抑制 Etoposide 诱导的 U937 细胞 caspase-3 活化，IC50为 79 μg/mL。
T0132	Etoposide VP-16,依托泊苷,依托泊甙,VP-16-213	Apoptosis; Mitophagy; Topoisomerase; Antibacterial; Antibiotic; Autophagy	Apoptosis; Autophagy; DNA Damage/DNA Repair; Microbiology/Virology
	Etoposide (VP-16-213) 是一种拓扑异构酶 II 的抑制剂，通过与拓扑异构酶 II 和 DNA 形成复合物来抑制 DNA 合成 (IC50=60.3 μM)。Etoposide 具有抗肿瘤活性，可以诱导细胞凋亡、自噬。
T6431	Levoleucovorin Calcium 左亚叶酸钙,Calcium Levofolinate,CL307782	Others; Antifolate	Cell Cycle/Checkpoint; Others
	Levoleucovorin Calcium (CL307782) 是一种亚叶酸的钙盐，在癌症化疗中用作辅助剂。
T22286	Cyanosafracin B Cyanoquinonamine,氰基番红菌素 B,CBR28-1	Others	Others
	Cyanosafracin B (Cyanoquinonamine) 是一种合成 Phthalascidin Pt-650 及 Ecteinascidin ET-743 的起始原料。
T1285	Anethole trithione 茴三硫,Anetholtrithion	Others; AChR	Neuroscience; Others
	Anethole trithione (Anetholtrithion) 是硫杂环胆碱，是一种胆汁分泌刺激剂，可增强唾液分泌并增加 mAChR 受体，用于口干症的研究。
T1156	Palonosetron hydrochloride 盐酸帕洛诺司琼,RS 25259 197,Palonosetron HCl,RS 25259	5-HT Receptor	GPCR/G Protein; Neuroscience
	Palonosetron hydrochloride (RS 25259) 是一种 5-HT3 拮抗剂，用于预防和治疗化疗引起的恶心和呕吐。
T3924	Astragaloside II 黄芪皂苷 II,Astrasieversianin VIII	TGF-beta/Smad	Stem Cells
	Astragaloside II (Astrasieversianin VIII) 是一种分离自黄芪中的天然化合物。
T4S0094	Hydroxygenkwanin 羟基芫花素,Luteolin 7-methylether,7-O-Methylluteolin	Antioxidant	oxidation-reduction
	Hydroxygenkwanin (Luteolin 7-methylether) 是一种丁香达芙妮的主要成分，是一种天然的类黄酮化合物。它具有抗氧化，抗神经胶质瘤能力和抗癌作用。
T2S1120	Ganoderenic acid B	P-gp	Membrane transporter/Ion channel; Neuroscience
	Ganoderenic acid B 是一种从Ganoderma lucidum 中提取的天然产物，可以通过抑制ABCB1的转运功能，增强化疗药物对ABCB1介导的耐多药癌细胞的细胞毒性来发挥作用。
T3729	Ethyl gallate Nipagallin A,Phyllemblin,gallic acid ethyl ester,没食子酸乙酯	MMP; NF-κB; Akt; Antibacterial	Cytoskeletal Signaling; Microbiology/Virology; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Ethyl gallate (gallic acid ethyl ester) 是一种非类黄酮酚过氧化氢清除剂。
T2563	Acetyl-L-carnitine hydrochloride Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,乙酰-L-肉(毒)碱盐酸盐,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) 是一种由内源性左旋肉碱的乙酰化形式的盐酸盐组成的营养补充剂，具有潜在的神经保护、认知增强、抗抑郁和免疫调节活性。还可缓解化疗、糖尿病或其他疾病引起的周围神经病变。此外，乙酰左旋肉碱可能通过增加T淋巴细胞成熟来调节免疫反应，并可能下调促炎细胞因子对病毒(如SARS-CoV-2)的反应。它还可能破坏ACE2信号通路并抑制活性氧(ROS)的产生。
T37984	D-Fructose-1,6-bisphosphate sodium salt hydrate	Others	Others
	D-Fructose-1,6-bisphosphate sodium salt hydrate 是碳水化合物代谢的中间体，包括糖酵解和糖异生。在糖酵解过程中，它是由磷酸果糖激酶磷酸化果糖-6-磷酸产生的。由果糖-1,6-二磷酸酶-1介导的逆反应是糖异生的限速步骤之一。同样的反应也发生在植物的叶绿体中，D-Fructose-1,6-bisphosphate sodium salt hydrate 作为还原性戊糖磷酸循环的一部分。由于癌细胞采用糖酵解作为代谢能量产生的主要来源，这一途径已成为癌症化疗的主要靶点。
T35000	Uproleselan sodium GMI 1271,GMI1271,GMI-1271
	Uproleselan sodium (GGI-1271) is a small molecule E-selector antagonist originally targeted at AML as an adjuvant to standard chemotherapy for hematological malignancies.
T3S0205	β-Hederin Beta-Hederin,β-常春藤素	Parasite	Microbiology/Virology
	β-Hederin 是从 Hedera helix L.(Araliaceae) 分离得到的一种皂苷，具有抗利什曼虫活性。它对乳腺癌细胞有凋亡作用，有望成为乳腺癌化疗的候选药物。
T4735	2'-Deoxyuridine 5'-monophosphate disodium 2'-脱氧尿苷-5'-单磷酸二钠,2'-dUMP⋅2Na,2-脱氧尿嘧啶核苷-5'-单磷酸二钠盐,2'-Deoxyuridine 5'-monophosphate disodium salt	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxyuridine 5'-monophosphate disodium (2'-dUMP⋅2Na) salt 能够被双底物酶胸苷酸合酶(TS) 还原甲基化为 dTMP (2'-deoxythymidine 5'-monophosphate)。其中 dTMP 是 DNA 合成所需的核苷酸。
T66078	Cardamonin
	Cardamonin, a chalcone extracted from cardamom spice with anti-inflammatory and anti-tumor activities. Cardamonin decreased viability of NPC(Nasopharyngeal carcinoma ) cells in a concentration-dependent manner. The IC50 values were 16.22 μM(CNE-1), 14.34 μM (CNE-2), 16.50 μM (HONE-1), and 68.12 μM (SUNE-1). Moreover, the expression level of the proapoptotic effector protein Bax and Bid was also markedly increased after treatment with cardamonin（15μM） in CNE-2 cells.In vivo, cardamonin (25 mg/kg ...

天然产物

Cat.No: T2217

Synonym: Baccatin III,三尖杉宁碱

Target: Microtubule Associated

Cat.No: T21936

Synonym: 2,2′-亚甲基双(1,3-环己二酮)

Target: Caspase

Cat.No: T0132

Synonym: VP-16,依托泊苷,依托泊甙,VP-16-213

Target: Apoptosis, Mitophagy, Topoisomerase, Antibacterial, Antibiotic, Autophagy

Levoleucovorin Calcium

Cat.No: T6431

Synonym: 左亚叶酸钙,Calcium Levofolinate,CL307782

Target: Others, Antifolate

Cyanosafracin B

Cat.No: T22286

Synonym: Cyanoquinonamine,氰基番红菌素 B,CBR28-1

Target: Others

Anethole trithione

Cat.No: T1285

Synonym: 茴三硫,Anetholtrithion

Target: Others, AChR

Palonosetron hydrochloride

Cat.No: T1156

Synonym: 盐酸帕洛诺司琼,RS 25259 197,Palonosetron HCl,RS 25259

Target: 5-HT Receptor

Astragaloside II

Cat.No: T3924

Synonym: 黄芪皂苷 II,Astrasieversianin VIII

Target: TGF-beta/Smad

Hydroxygenkwanin

Cat.No: T4S0094

Synonym: 羟基芫花素,Luteolin 7-methylether,7-O-Methylluteolin

Target: Antioxidant

Ganoderenic acid B

Cat.No: T2S1120

Target: P-gp

Cat.No: T3729

Synonym: Nipagallin A,Phyllemblin,gallic acid ethyl ester,没食子酸乙酯

Target: MMP, NF-κB, Akt, Antibacterial

Acetyl-L-carnitine hydrochloride

Cat.No: T2563

Synonym: Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,乙酰-L-肉(毒)碱盐酸盐,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride

Target: Others, Endogenous Metabolite

D-Fructose-1,6-bisphosphate sodium salt hydrate

Cat.No: T37984

Target: Others

Uproleselan sodium

Cat.No: T35000

Synonym: GMI 1271,GMI1271,GMI-1271

Cat.No: T3S0205

Synonym: Beta-Hederin,β-常春藤素

Target: Parasite

2'-Deoxyuridine 5'-monophosphate disodium

Cat.No: T4735

Synonym: 2'-脱氧尿苷-5'-单磷酸二钠,2'-dUMP⋅2Na,2-脱氧尿嘧啶核苷-5'-单磷酸二钠盐,2'-Deoxyuridine 5'-monophosphate disodium salt

Target: Others, Endogenous Metabolite

Cat.No: T66078

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼