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Search Results for " mif "

Targets Recommended: Others

105

抑制剂 & 化合物

9

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T60850	MIF-IN-2	Others	Others
	MIF-IN-2 是一种杂环巨噬细胞迁移抑制因子 (MIF) 抑制剂，具有抗癌活性，可用于研究癌症和自身免疫性疾病。
T3680	ISO-1 MIF Antagonist,ISO 1	Others	Others
	ISO-1 (MIF Antagonist) 是一种巨噬细胞移动抑制因子(MIF) 拮抗剂(IC50:7 μM)。
T60809	MIF-IN-1
	MIF-IN-1 (compound 14) 是巨噬细胞迁移抑制因子(MIF)的抑制剂，pIC50为6.87。巨噬细胞迁移抑制因子 (MIF) 是一种与多种疾病相关的促炎细胞因子，包括神经退行性疾病。
T62344	MIF-IN-3
	MIF-IN-3 是一种迁移抑制因子 (MIF) 抑制剂。MIF-IN-3 能够用于免疫炎症相关疾病的研究。
T69525	MIF degrader MD13
	MIF degrader MD13 is involved in protein-protein interactions that play key roles in inflammation and cancer. Current strategies to develop small molecule modulators of MIF functions are mainly restricted to the MIF tautomerase active siteMIF degrader MD13. MD13 also exhibits antiproliferative effect in a 3D tumor spheroid model. In conclusion, we describe the first MIF-directed PROTAC (MD13) as a research tool, which also demonstrates the potential of PROTACs in cancer therapy.
T63322	MIF-IN-4 hydrochloride
	MIF-IN-4 hydrochloride 是一种巨噬细胞移动抑制因子(MIF)的有效抑制剂，其pIC50值在5.01-6之间。其中 MIF 是发现于抑制巨噬细胞迁移过程中的一种细胞因子。
T61705	MIF-IN-6
	MIF-IN-6 (compound 2d) is an effective inhibitor of macrophage migration inhibitory factor (MIF), exhibiting an IC50 of 1.4 μM and a Ki value of 0.96 μM. MIF-IN-6 effectively reduces MIF-induced ERK phosphorylation and impedes A549 cell proliferation [1].
T61218	MIF-IN-5
	MIF-IN-5 (compound 1d) is a highly effective and reversible competitive inhibitor of macrophage migration inhibitory factor (MIF), exhibiting an IC 50 of 4.8 μM and a Ki value of 3.3 μM [1].
T73676	MIF-1 TFA
	MIF-1 TFA（Melanostatin）是一种内源性脑肽，具有有效调节多巴胺受体变构的作用，并抑制黑色素生成。此外，它通过阻断阿片受体的激活，调控吗啡的镇痛效果及应激诱导的镇痛（SIA）。MIF-1 TFA 能直接穿过血脑屏障（BBB）进入中枢神经系统。
T60388	MIF098	Others	Others
	MIF098 是一种巨噬细胞迁移抑制因子 (MIF) 拮抗剂。MIF098，抑制与 SLE 相关的肺动脉高压，抑制肺平滑肌细胞(PASMC)增殖和迁移。MIF098 可用于研究特发性肺动脉高压。
T76186	Tyr-W-MIF-1
	Tyr-W-MIF-1 是一种阿片四肽，具有阿片和抗阿片活性。Tyr-W-MIF-1 可诱导镇痛。
T7844	4-IPP 4-Iodo-6-phenylpyrimidine	Others	Others
	4-IPP (4-Iodo-6-phenylpyrimidine) 是一种巨噬细胞迁移抑制因子 (MIF) 的特异性自杀底物，也是 MIF 的不可逆抑制剂。
T63169	MIF2-IN-1
	MIF2-IN-1 (compound 5d) 是一种有效的 MIF2 互变异构酶抑制剂 (IC50: 1.0 μM)。MIF2-IN-1 通过 MAPK 通路，阻滞细胞周期，进而抑制非小细胞肺癌细胞的增殖。MIF2-IN-1 具有潜力进行癌症疾病的研究。
TP1127L1	Nemifitide acetate(173240-15-8 free base) INN 00835 acetate	5-HT Receptor	GPCR/G Protein; Neuroscience
	Nemifitide acetate(173240-15-8 free base) (INN 00835 acetate) 是一种合成的五肽抗抑郁药，具有快速起效的潜力。它是黑色素细胞抑制因子 (MIF) 的肽类似物。
T2065	Bioymifi DR5 Activator	Apoptosis; TNF	Apoptosis
	Bioymifi (DR5 Activator) 是一种 TRAIL 受体DR5激活剂，与DR5的胞外结构域结合，Kd 为 1.2 μM，它可诱导 DR5 聚集，导致细胞凋亡。
T20953	Lumiflavine Lumilactoflavin,Lumiflavin,光黃素	Others	Others
	Lumiflavine (Lumilactoflavin) 是 riboflavine 的结构类似物，能够用于 riboflavin 摄取量的检测。
T23536	Xamoterol hemifumarate ICI 118587 hemifumarate,Corwin hemifumarate	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Xamoterol hemifumarate 是一种具有强效性和选择性的β1-肾上腺素受体激动剂。Xamoterol hemifumarate 是研究心律失常和 β1-肾上腺素能刺激与 IKr 之间关系的潜在化合物。
T21979	P32/98 (hemifumarate)
	P32/98 hemifumarate 为二肽基肽酶 IV (DPP4) 抑制剂，可在Zucker糖尿病大鼠模型中改善葡萄糖耐量、提高胰岛素敏感性及增强β细胞反应性，具有预防2型糖尿病的潜力。
T33876L1	Panomifene TFA Panomifene TFA(77599-17-8 Free base),EGIS5650 TFA,GYKl13504 TFA	Estrogen/progestogen Receptor	Endocrinology/Hormones
	Panomifene TFA（GYKl13504 TFA）是一种小分子 ERs 拮抗剂，具有抗癌活性，可用于研究乳腺癌和肌肉骨骼疾病。
T6381	Amifostine trihydrate Ethyol trihydrate,WR2721,三水氨磷汀,Amifostine	Others; HIF/HIF Prolyl-Hydroxylase	Chromatin/Epigenetic; Metabolism; Others
	Amifostine trihydrate (WR2721) 是一种广谱细胞保护剂和辐射防护剂。它可选择性保护正常组织免受放射线和化学疗法造成的损害。它是有效的HIF-α1和p53诱导剂。它通过清除氧衍生的自由基来保护细胞免受损伤。它可降低肾脏毒性并具有抗血管生成作用。
T4640	Parimifasor LYC30937	Others	Others
	Parimifasor (LYC30937) 是免疫调节剂，具有抗炎作用。
T13385	Zamifenacin fumarate 扎非那星富马酸盐,UK-76654 fumarate	AChR	Neuroscience
	Zamifenacin fumarate (UK-76654 fumarate) 是肠道选择性毒蕈碱M3受体的有效拮抗剂，可显著降低肠易激综合症的结肠蠕动。
T33876L	Panomifene HCl EGIS5650 HCl,GYKI 13504 HCl,Panomifene HCl(77599-17-8 Free base),EGIS 5650 HCl	HER	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Panomifene HCl 是一种选择性抗雌激素化合物，具有抗肿瘤活性，可用于治疗乳腺癌。
T68100	Mifentidine DA 4577	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Mifentidine (DA 4577) 是一种可口服的 H2 受体拮抗剂，可用于研究胃排空和实验性胃和十二指肠溃疡。
T0104	Umifenovir hydrochloride 盐酸阿比朵尔,Arbidol hydrochloride,Arbidol HCl,盐酸阿比多尔	SARS-CoV; Influenza Virus	Microbiology/Virology
	Umifenovir hydrochloride (Arbidol HCl) 是一种口服有效的广谱抗病毒药物，对多种包膜和非包膜病毒均有活性。它被用作抗流感病毒剂，可通过阻断病毒与宿主细胞膜的融合来抑制包膜病毒的细胞侵袭。它是一种 SARS-CoV-2 抑制剂，具有抗炎活性。
T16074	Mifobate SR-202,米福贝特	PPAR	DNA Damage/DNA Repair; Metabolism
	Mifobate (SR-202) 是一种有效且特异性的 PPARγ拮抗剂，可选择性抑制噻唑烷二酮 (TZD) 诱导的 PPARγ 转录活性，IC50为140 μM，具有抗肥胖和抗糖尿病作用。
T8589	(±)-Amiflamine 4-(dimethylamino)-alpha,4-(2-氨基丙基)-N,N,3-三甲基苯胺,Amiflamine,2-dimethylphenethylamine	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	(±)-Amiflamine (2-dimethylphenethylamine) 是一种单胺氧化酶(MAO-A)，pIC50=5.57。
TQ0133	Amifostine thiol dihydrochloride WR 1065,硫代乙基氨基乙基胺盐酸盐	p53	Apoptosis
	Amifostine thiol dihydrochloride (WR 1065) 可通过 JNK 依赖性信号通路激活 p53。它还可以保护正常组织免受某些抗癌药物的毒性作用。
T3289	Amifostine 氨磷汀,Ethyol,WR2721,Gammaphos	Others; HIF/HIF Prolyl-Hydroxylase	Chromatin/Epigenetic; Metabolism; Others
	Amifostine (Ethyol) 是一种广谱细胞保护剂和辐射防护剂，具有清除自由基的作用。它可选择性保护正常组织免受放射线和化学疗法造成的损害。它是有效的 HIF-α1和 p53诱导剂，可降低肾脏毒性并具有抗血管生成作用。
T39520	Vamifeport VIT-2763	Ferroptosis	Apoptosis
	Vamifeport (VIT-2763) 是一种新型具有口服活性且靶向铁转运蛋白的抑制剂，可降低 SCD Townes 模型中的溶血标志物。VIT-2763 可改善贫血和红细胞生成，可改善血管炎症，可研究 β-地中海贫血。
T67816	Alamifovir PM
	Alamifovir PM 是 Alamifovir 的类似物。Alamifovir 是一种 HBV 特异性抗病毒化合物。
T8623	TMIFRY8XAG 4,4,-二(4-氟苯)氯丁烷,1,1'-(4-CHLOROBUTYLIDENE)BIS(4-FLUOROBENZENE),4-oxo-1,4-dihydroquinoline-2-carboxylic acid	Others	Others
	TMIFRY8XAG (4-oxo-1,4-dihydroquinoline-2-carboxylic acid) 是 Zerumbone 的衍生物，对 HeLa 癌细胞具有潜在的抗肿瘤作用。
T1492	Gemifloxacin mesylate LB-20304a,甲磺酸吉米沙星,SB-265805S,Gemifloxacin mesylate	DNA gyrase; Topoisomerase; Antibacterial	DNA Damage/DNA Repair; Microbiology/Virology
	Gemifloxacin mesylate (Gemifloxacin mesylate) 是一种喹诺酮类口服广谱抗菌剂，可研究轻中度肺炎和慢性支气管炎的急性细菌性发作。
T7282	Tenofovir alafenamide hemifumarate GS-7340 (hemifumarate),Tenofovir alafenamide fumarate,替诺福韦艾拉酚胺富马酸盐	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) 是 HIV 逆转录酶核苷酸抑制剂替诺福韦的口服膦酰胺前药。
T1102	Mifepristone C-1073,RU486,RU 38486,米非司酮	Glucocorticoid Receptor; Estrogen/progestogen Receptor; Progesterone Receptor; NO Synthase; Autophagy	Autophagy; Endocrinology/Hormones; Immunology/Inflammation; Others
	Mifepristone (C-1073) 是一种黄体酮受体和糖皮质激素受体拮抗剂，在体外实验中的 IC50值分别为 0.2 nM 和 2.6 nM。
T4497	Amifampridine 3,4-Pyridinediamine,Pyridine-3,4-Diamine,阿米吡啶,3,4-Diaminopyridine	Others	Others
	Amifampridine (3,4-Diaminopyridine) 可用于罕见肌肉疾病的研究。
T17254	Amifloxacin Win49375,氨氟沙星	Antibacterial	Microbiology/Virology
	Amifloxacin (Win49375) 是有效的喹诺酮类抗菌剂。
T7308	Nomifensine NOMIFENSINE MALEATE,(±)-Nomifensin,诺米芬辛	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Nomifensine ((±)-Nomifensin) 是一种去甲肾上腺素-多巴胺再摄取抑制剂，可防止多巴胺再摄取进入突触体。
T6241	Quetiapine hemifumarate Quetiapine Fumarate,ICI-204636,富马酸喹硫平	Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Quetiapine hemifumarate (ICI-204636) 是5-HT 受体激动剂和多巴胺受体拮抗剂，对人5-HT1A 和人D2的pEC50值分别为 4.77 和 6.33，具有抗抑郁和抗焦虑作用。
T23372	SMIFH2	Others	Others
	SMIFH2 是formin 特异性抑制剂。它利用 Formins 阻碍肌动蛋白聚合，影响肌动蛋白细胞骨架。
T71973	Gilteritinib hemifumarate ASP2215 hemifumarate	FLT; TAM Receptor	Angiogenesis; Tyrosine Kinase/Adaptors
	Gilteritinib hemifumarate (ASP2215 hemifumarate) 是一种高效的 ATP 竞争性 FLT3（IC50 ： 0.29 nM）和 AXL（IC50： 0.73 nM）双重抑制剂，可用于治疗复发或难治性 FLT3 突变的 AML。
T37538	Amifostine thiol
	Amifostine thiol (WR-1065), the active metabolite of cytoprotector Amifostine, serves as a cytoprotective agent possessing radioprotective properties. It activates p53 via a JNK-dependent signaling pathway[1][2][3].
T7070	Nomifensine maleate Nomifensine (maleate),诺米芬新马来酸盐,(±)-Nomifensine maleat	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Nomifensine maleate (Nomifensine (maleate)) 是一种多巴胺摄取的选择性抑制剂，可用于成人注意力缺陷障碍的研究。
T27322	Fispemifene HM-101,HM 101,HM101	Others	Others
	Fispemifene (HM-101) 是一种雌激素受体调节剂（SERM），可用于治疗泌尿生殖系统综合征和阴道萎缩。
T1520	Aliskiren hemifumarate 阿利克仑半富马酸盐,CGP 60536,SPP 100,CGP60536B	RAAS; Autophagy	Autophagy; Endocrinology/Hormones
	Aliskiren hemifumarate (CGP60536B) 一种可口服非肽肾素抑制剂，IC50为1.5 nM，具有抗高血压活性。
TP1127	Nemifitide diTFA INN 00835 diTFA	5-HT Receptor	GPCR/G Protein; Neuroscience
	Nemifitide diTFA (INN 00835 diTFA) 是一种合成的五肽，是一种可透过血脑屏障的黑色素细胞抑制因子 (MIF) 的肽类似物，具有有效的抗抑郁活性。
T3289L2	Amifostine sodium WR-2721 sodium,WR2721 sodium,WR 2721 sodium
	Amifostine sodium is a phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
T38738	Imifoplatin Imifoplatin,PT-112
	Imifoplatin is a platinum-based agent belonging to the phosphaplatin family. Imifoplatin exhibits antineoplastic activity.
T63916	MAX-40279 hemifumarate
	MAX-40279 hemifumarate 是有效的 FLT3 激酶和 FGFR 激酶的双重抑制剂。MAX-40279 hemifumarate 对急性髓性白血病 (AML) 表现出研究潜力。
T17283	Zamifenacin UK-76654	Others	Others
	Zamifenacin obviously decreases colonic motility in irritable bowel syndrome. Zamifenacin is an effective gut-selective muscarinic M3 receptor antagonist.

化合物

Cat.No: T60850

Target: Others

Cat.No: T3680

Synonym: MIF Antagonist,ISO 1

Target: Others

Cat.No: T60809

Cat.No: T62344

MIF degrader MD13

Cat.No: T69525

MIF-IN-4 hydrochloride

Cat.No: T63322

Cat.No: T61705

Cat.No: T61218

Cat.No: T73676

Cat.No: T60388

Target: Others

Cat.No: T76186

Cat.No: T7844

Synonym: 4-Iodo-6-phenylpyrimidine

Target: Others

Cat.No: T63169

Nemifitide acetate(173240-15-8 free base)

Cat.No: TP1127L1

Synonym: INN 00835 acetate

Target: 5-HT Receptor

Cat.No: T2065

Synonym: DR5 Activator

Target: Apoptosis, TNF

Cat.No: T20953

Synonym: Lumilactoflavin,Lumiflavin,光黃素

Target: Others

Xamoterol hemifumarate

Cat.No: T23536

Synonym: ICI 118587 hemifumarate,Corwin hemifumarate

Target: Adrenergic Receptor

P32/98 (hemifumarate)

Cat.No: T21979

Cat.No: T33876L1

Synonym: Panomifene TFA(77599-17-8 Free base),EGIS5650 TFA,GYKl13504 TFA

Target: Estrogen/progestogen Receptor

Amifostine trihydrate

Cat.No: T6381

Synonym: Ethyol trihydrate,WR2721,三水氨磷汀,Amifostine

Target: Others, HIF/HIF Prolyl-Hydroxylase

Cat.No: T4640

Synonym: LYC30937

Target: Others

Zamifenacin fumarate

Cat.No: T13385

Synonym: 扎非那星富马酸盐,UK-76654 fumarate

Target: AChR

Cat.No: T33876L

Synonym: EGIS5650 HCl,GYKI 13504 HCl,Panomifene HCl(77599-17-8 Free base),EGIS 5650 HCl

Target: HER

Cat.No: T68100

Synonym: DA 4577

Target: Histamine Receptor

Umifenovir hydrochloride

Cat.No: T0104

Synonym: 盐酸阿比朵尔,Arbidol hydrochloride,Arbidol HCl,盐酸阿比多尔

Target: SARS-CoV, Influenza Virus

Cat.No: T16074

Synonym: SR-202,米福贝特

Target: PPAR

(±)-Amiflamine

Cat.No: T8589

Synonym: 4-(dimethylamino)-alpha,4-(2-氨基丙基)-N,N,3-三甲基苯胺,Amiflamine,2-dimethylphenethylamine

Target: MAO, Monoamine Oxidase

Amifostine thiol dihydrochloride

Cat.No: TQ0133

Synonym: WR 1065,硫代乙基氨基乙基胺盐酸盐

Target: p53

Cat.No: T3289

Synonym: 氨磷汀,Ethyol,WR2721,Gammaphos

Target: Others, HIF/HIF Prolyl-Hydroxylase

Cat.No: T39520

Synonym: VIT-2763

Target: Ferroptosis

Cat.No: T67816

Cat.No: T8623

Synonym: 4,4,-二(4-氟苯)氯丁烷,1,1'-(4-CHLOROBUTYLIDENE)BIS(4-FLUOROBENZENE),4-oxo-1,4-dihydroquinoline-2-carboxylic acid

Target: Others

Gemifloxacin mesylate

Cat.No: T1492

Synonym: LB-20304a,甲磺酸吉米沙星,SB-265805S,Gemifloxacin mesylate

Target: DNA gyrase, Topoisomerase, Antibacterial

Tenofovir alafenamide hemifumarate

Cat.No: T7282

Synonym: GS-7340 (hemifumarate),Tenofovir alafenamide fumarate,替诺福韦艾拉酚胺富马酸盐

Target: HIV Protease, Reverse Transcriptase

Cat.No: T1102

Synonym: C-1073,RU486,RU 38486,米非司酮

Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, NO Synthase, Autophagy

Cat.No: T4497

Synonym: 3,4-Pyridinediamine,Pyridine-3,4-Diamine,阿米吡啶,3,4-Diaminopyridine

Target: Others

Cat.No: T17254

Synonym: Win49375,氨氟沙星

Target: Antibacterial

Cat.No: T7308

Synonym: NOMIFENSINE MALEATE,(±)-Nomifensin,诺米芬辛

Target: Dopamine Receptor

Quetiapine hemifumarate

Cat.No: T6241

Synonym: Quetiapine Fumarate,ICI-204636,富马酸喹硫平

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor

Cat.No: T23372

Target: Others

Gilteritinib hemifumarate

Cat.No: T71973

Synonym: ASP2215 hemifumarate

Target: FLT, TAM Receptor

Amifostine thiol

Cat.No: T37538

Nomifensine maleate

Cat.No: T7070

Synonym: Nomifensine (maleate),诺米芬新马来酸盐,(±)-Nomifensine maleat

Target: Dopamine Receptor

Cat.No: T27322

Synonym: HM-101,HM 101,HM101

Target: Others

Aliskiren hemifumarate

Cat.No: T1520

Synonym: 阿利克仑半富马酸盐,CGP 60536,SPP 100,CGP60536B

Target: RAAS, Autophagy

Nemifitide diTFA

Cat.No: TP1127

Synonym: INN 00835 diTFA

Target: 5-HT Receptor

Amifostine sodium

Cat.No: T3289L2

Synonym: WR-2721 sodium,WR2721 sodium,WR 2721 sodium

Cat.No: T38738

Synonym: Imifoplatin,PT-112

MAX-40279 hemifumarate

Cat.No: T63916

Cat.No: T17283

Synonym: UK-76654

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN6730	Epoxyazadiradione	NF-κB	NF-κB
	Epoxyazadiradione 是从印楝果实中得到的柠檬苦素。它能够可逆的、非竞争性的抑制人类、约氏疟原虫、疟原虫的互变异构酶活性。它具有抗疟原虫和人类 MIF 诱导的促炎反应的潜力。
T3383	Cimifugin 升麻素,Cimitin	Others	Others
	Cimifugin (Cimitin) 是中草药Saposhnikovia divaricate 的一种生物活性成分。它能够调节紧密连接减少上皮衍生的主动关键因子，对过敏性炎症产生抑制作用。
T3805	Prim-O-glucosylcimifugin 升麻苷,Cimifugin beta-D-glucopyranoside,Cimifugin 7-glucoside	TNF; COX; JAK; NO Synthase	Angiogenesis; Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Neuroscience; Stem Cells
	Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) 具有强效的抗炎作用。通过调节 JAK2/STAT3 信号传导可抑制iNOS 和COX-2表达。
TN1496	Cimifugin 4'-O-β-D-glucopyranoside 升麻素-4'-O-Β-D-吡喃葡萄糖苷,Cimifugin 4'-O-beta-D-glucopyranoside	Others	Others
	Cimifugin 4'-O-beta-D-glucopyranoside is a natural product
TN3812	Dehydrovomifoliol	AChR	Neuroscience
	Dehydrovomifoliol could be a marker of Polish heather honey. Dehydrovomifoliol exhibits moderate acetylcholinesterase (AChE) inhibitory activities. Dehydrovomifoliol shows significant cytotoxic activities against three human cancer cell lines, namely, HONE-1 nasopharyngeal, KB oral epidermoid carcinoma, and HT29 colorectal carcinoma cells, and the IC(50) values in the range 3.7-8.1 microM.
TN5250	Vomifoliol	VEGFR; NF-κB; HIF	Angiogenesis; Chromatin/Epigenetic; NF-κB; Tyrosine Kinase/Adaptors
	Vomifoliol is most likely the immediate precursor of dehydrovomifoliol, because of the organism converted abscisic acid (ABA), to dehydrovomifoliol as the major metabolise, and a cell-free extract exhibits vomifoliol dehydrogenase activity. Vomifoliol and
T8204	Gummiferin	Others	Others
	Gummiferin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 T8204，CAS号为 33286-30-5。
T83532	(Rac)-Dehydrovomifoliol PBI 344
	(Rac)-Dehydrovomifoliol (PBI 344)为Euphorbia peplus中存在的一种双环萜化合物。
TN2095	Pomiferin	NOS; NF-κB; PDE	Immunology/Inflammation; Metabolism; NF-κB
	Pomiferin is a natural product inhibitor of carbonic anhydrase I and II isoenzymes. It has anticancer, antibacterial and antidiabetic properties. Pomiferin has anti-inflammatory and neuroprotective activities.

天然产物

Epoxyazadiradione

Cat.No: TN6730

Target: NF-κB

Cat.No: T3383

Synonym: 升麻素,Cimitin

Target: Others

Prim-O-glucosylcimifugin

Cat.No: T3805

Synonym: 升麻苷,Cimifugin beta-D-glucopyranoside,Cimifugin 7-glucoside

Target: TNF, COX, JAK, NO Synthase

Cimifugin 4'-O-β-D-glucopyranoside

Cat.No: TN1496

Synonym: 升麻素-4'-O-Β-D-吡喃葡萄糖苷,Cimifugin 4'-O-beta-D-glucopyranoside

Target: Others

Dehydrovomifoliol

Cat.No: TN3812

Target: AChR

Cat.No: TN5250

Target: VEGFR, NF-κB, HIF

Cat.No: T8204

Target: Others

(Rac)-Dehydrovomifoliol

Cat.No: T83532

Synonym: PBI 344

Cat.No: TN2095

Target: NOS, NF-κB, PDE

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05176	AMH Protein, Human, Recombinant (His) MIS,anti-Mullerian hormone,MIF	Human	HEK293 Cells
	Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. BMP15 up-regulates the transcription of AMH and that the inhibition of p38 MAPK decreases the BMP15-induced expression of AMH and SOX9, suggesting that BMP15 up-regulates the expression of AMH via the p38 MAPK signaling pathway, and thi...
TMPY-01356	S100A8 Protein, Human, Recombinant (His) 60B8AG,MRP-8,MA387,NIF,L1Ag,S100 calcium binding protein A8,...	Human	Baculovirus Insect Cells
	S100A8 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 12.2 kDa and the accession number is P05109.
TMPY-01357	S100A9 Protein, Human, Recombinant (His) MRP14,P14,LIAG,CFAG,CGLB,CAGB,NIF,MIF,S100 calcium ...	Human	Baculovirus Insect Cells
	S100A9 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 14.6 kDa and the accession number is P06702.
TMPY-02342	MIF Protein, Mouse, Recombinant GIF,macrophage migration inhibitory factor (glycosylation-in...	Mouse	E. coli
	MIF Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12.5 kDa and the accession number is P34884.
TMPY-02145	MIF Protein, Mouse, Recombinant (His) GIF,macrophage migration inhibitory factor (glycosylation-in...	Mouse	HEK293 Cells
	MIF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.8 kDa and the accession number is P34884.
TMPY-02095	MIF Protein, Human, Recombinant (His) macrophage migration inhibitory factor (glycosylation-inhibi...	Human	HEK293 Cells
	MIF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.8 kDa and the accession number is P14174.
TMPY-01330	S100A9 Protein, Human, Recombinant CAGB,MIF,60B8AG,S100 calcium binding protein A9,CGL...	Human	E. coli
	S100A9 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 26 and 13 kDa and the accession number is P06702.
TMPK-01257	DDT Proten, Canine, Recombinant (His) EC 4.1.1.84,DDCT,D-DT,MIF2	Canine	E. coli
	D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT protein also is present in most tissues and circulates in serum at similar concentrations as MIF. D-DT binds the MIF cell surface receptor complex, CD74/CD44, with high affinity and induces similar cell signaling and effector functions. DDT Proten, Canine, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predict...
TMPK-00864	DDT Protein, Human, Recombinant (His) Phenylpyruvate tautomerase II,D-dopachrome tautomerase,D-DT,...	Human	E. coli
	D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT protein also is present in most tissues and circulates in serum at similar concentrations as MIF. D-DT binds the MIF cell surface receptor complex, CD74/CD44, with high affinity and induces similar cell signaling and effector functions. DDT Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predict...
TMPK-00722	DDT Protein, Mouse, Recombinant (His) DDCT,D-dopachrome tautomerase,MIF2,Phenylpyruvate t...	Mouse	E. coli
	D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT protein also is present in most tissues and circulates in serum at similar concentrations as MIF. D-DT binds the MIF cell surface receptor complex, CD74/CD44, with high affinity and induces similar cell signaling and effector functions. DDT Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predict...
TMPK-01307	DDT Protein, Cynomolgus, Recombinant (His) MIF2,D-dopachrome decarboxylase,DDCT,D-DT,EC 4.1.1....	Cynomolgus	E. coli
	D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT protein also is present in most tissues and circulates in serum at similar concentrations as MIF. D-DT binds the MIF cell surface receptor complex, CD74/CD44, with high affinity and induces similar cell signaling and effector functions. DDT Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with N-His tag. The pr...
TMPJ-01037	CXCR4 Protein, Human, Recombinant (hFc) CXCR4,CD184,Fusin,D2S201E,FB22,HM89,HSY3RR,LAP3,LCR1,LESTR,N...	Human	HEK293 Cells
	C-X-C chemokine receptor type 4 (CXCR4) is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes. This receptor is one of several chemokine receptors that HIV isolates can use to infect CD4+ T cells. CXCR4 stands out for its pleiotropic roles in both physiological and pathological conditions and it represents a crucial target in drug development. CXCL12 is the principal CXCR4 specific liga...

重组蛋白

AMH Protein, Human, Recombinant (His)

Cat.No: TMPY-05176

Species: Human

Expression System: HEK293 Cells

S100A8 Protein, Human, Recombinant (His)

Cat.No: TMPY-01356

Species: Human

Expression System: Baculovirus Insect Cells

S100A9 Protein, Human, Recombinant (His)

Cat.No: TMPY-01357

Species: Human

Expression System: Baculovirus Insect Cells

MIF Protein, Mouse, Recombinant

Cat.No: TMPY-02342

Species: Mouse

Expression System: E. coli

MIF Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02145

Species: Mouse

Expression System: HEK293 Cells

MIF Protein, Human, Recombinant (His)

Cat.No: TMPY-02095

Species: Human

Expression System: HEK293 Cells

S100A9 Protein, Human, Recombinant

Cat.No: TMPY-01330

Species: Human

Expression System: E. coli

DDT Proten, Canine, Recombinant (His)

Cat.No: TMPK-01257

Species: Canine

Expression System: E. coli

DDT Protein, Human, Recombinant (His)

Cat.No: TMPK-00864

Species: Human

Expression System: E. coli

DDT Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00722

Species: Mouse

Expression System: E. coli

DDT Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01307

Species: Cynomolgus

Expression System: E. coli

CXCR4 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-01037

Species: Human

Expression System: HEK293 Cells

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