226
86
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73
Cat. No. | Product Name | ||
---|---|---|---|
L3500 | 组蛋白修饰化合物库 | 469 compounds | |
469 个组蛋白修饰相关的小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L8300 | 染色质修饰分子库 | 250 compounds | |
250 种染色质化学修饰相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0050 |
BCA Protein Quantification Kit
BCA蛋白浓度测定试剂盒 |
Solution in bottle | |
CL0096 |
Wnt/β-catenin/PORCN inhibitor/activator kit
Wnt/β-catenin/PORCN inhibitor/activator kit |
||
C0046 |
RIPA Lysis Buffer (Middle)
RIPA裂解液(中) |
Solution in bottle | |
C0047 |
RIPA Lysis Buffer (Weak)
RIPA裂解液(弱) |
Solution in bottle |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T15198 |
Edasalonexent
CAT-1004 |
NF-κB | NF-κB |
Edasalonexent (CAT-1004) 是一种可口服的 NF-κB 抑制剂,可用于改善杜氏肌营养不良症。 | |||
T76704 |
Tralokinumab
CAT-354,LP 0162 |
IL Receptor | Immunology/Inflammation |
Tralokinumab 是一种全人源 IgG4 单克隆抗体,对单独的 IL-13 亲和力较高。Tralokinumab 具有潜在的抗炎活性,可预防IL-13与受体相互作用和随后的下游信号传导,可用于研究特应性皮炎 (AD) 。 | |||
T1052 |
Proglumide
二丙谷酰胺 |
cholecystokinin | GPCR/G Protein |
Proglumide (Binoside) 是一种非肽的、口服具有活性的胆囊收缩素(CCK)-A/B 受体拮抗剂。它能够选择性阻断 CCK 在中枢神经系统中的作用。它能够抑制胃分泌,具有保护胃十二指肠粘膜的能力,并表现出抗癫痫和抗氧化活性。 | |||
T6015 |
Cathepsin Inhibitor 1
|
Cysteine Protease | Proteases/Proteasome |
Cathepsin inhibitor 1 是Cathepsin 的选择性抑制剂,能够抑制CatL(pIC50:7.9)、CatL2(pIC50:6.7)、CatS(pIC50:6.0)、CatK(pIC50:5.5)和CatB(pIC50:5.2)。 | |||
T60812 |
Cathepsin X-IN-1
|
Cysteine Protease | Proteases/Proteasome |
Cathepsin X-IN-1 (compound 25) 降低人前列腺癌细胞 PC-3 的迁移且具有较低的细胞毒性,它是组织蛋白酶 X 的有效抑制剂 (IC50 = 7.13 μM)。 | |||
TP1125 |
Insulin(cattle)
牛胰岛素,Insulin from bovine pancreas,胰岛素 |
IGF-1R | Tyrosine Kinase/Adaptors |
Insulin cattle (Insulin from bovine pancreas) 是一种在胰腺 β 细胞中产生的两链多肽激素,在很多哺乳动物细胞培养体系中用作生长因子。 | |||
T1742 |
4E1rcat
|
PERK; Autophagy | Apoptosis; Autophagy |
4E1RCat 是 cap 依赖性翻译抑制剂,可抑制 eIF4 g 与 eIF4E 的结合,IC50 为 3.2 μM。 | |||
T3532 |
5S rRNA modificator
FAI,Furoyl Acylimidazole |
Others | Others |
5S rRNA modificator (FAI) 是一种结构化 RNA 分子上 2'-羟基酰化的合适亲电试剂,产生与现有探针相当的精确结构信息。它可用于 5S rRNA RNA 修饰。 | |||
T9065 |
4-Isopropylcatechol
|
Others | Others |
4-Isopropylcatechol 是一种有效的脱色剂,可用于特定黑色素沉着症患者的局部治疗。 | |||
T8222 |
Selpercatinib
LOXO-292 |
c-RET | Apoptosis; Tyrosine Kinase/Adaptors |
Selpercatinib (LOXO-292) 是 RET 激酶抑制剂,抑制 RET (WT)、RET (V804M) 、RET (G810R)的 IC50分别为 14.0 nM、24.1 nM、530.7 nM,具有抗肿瘤活性。 | |||
T2320 |
Indacaterol
|
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Indacaterol 是一种超长效β-肾上腺素受体激动剂。 | |||
T22344 |
Icatibant Acetate
|
Bradykinin Receptor | GPCR/G Protein |
Icatibant acetate 是一种特异性缓激肽 B2 受体拮抗剂,其 IC50=1.07 nM,Ki=0.798 nM。 | |||
TQ0038 |
Brensocatib
AZD7986,INS 1007 |
Proteasome | Proteases/Proteasome; Ubiquitination |
Brensocatib (AZD7986) 是一种二肽基肽酶 1 (DPP1) 抑制剂,在人,小鼠,大鼠,狗和兔中的pIC50分别为 6.85, 7.6, 7.7, 7.8 和 7.8。 | |||
T77747 |
Adecatumumab
MT 201 |
Others | Others |
Adecatumumab ( MT201) 是 全人针对人 EpCAM 的 IgG1 单克隆抗体。Adecatumumab 具有潜在的抗癌活性,可用于研究乳腺癌。 | |||
T15471 |
Hepronicate
Megrin |
Others | Others |
Hepronicate(Megrin) 是一种具有降血脂和血管扩张活性的小分子化合物。 | |||
T22043 |
BCATc Inhibitor 2
|
Others | Others |
BCATc Inhibitor 2 是选择性分支链氨基转移酶抑制剂,可用于神经退行性疾病的研究。能够抑制 rBCATc (IC50:0.2 μM),hBCATc (IC50:0.8 μM)、 rBCATm (IC50:3.0 μM)。其中BCATc 也称为 BCAT1,存在于细胞质基质中的亚型。 | |||
T39598 |
4-Chlorocatechol
|
Others | Others |
4-Chlorocatechol, a significant degradation product of 4-chloro-2-aminophenol (4C2AP), serves as a substrate for both catechol 1,2-dioxygenases and chlorocatechol dioxygenase [1] [2]. | |||
T5198 |
Bobcat339
盐酸Bobcat339,Bobcat339 hydrochloride |
DNA Methyltransferase | Chromatin/Epigenetic |
Bobcat339 是一种基于胞嘧啶的选择性TET 酶抑制剂,抑制TET1和TET2的IC50值分别为 33 和 73 μM。它可作为靶向 DNA 甲基化和基因转录新疗法的起点,用于表观遗传学领域研究。 | |||
T40421 |
4,5-Dichlorocatechol
|
Others | Others |
4,5-Dichlorocatechol 是广谱的pseudomonas chlororaphisRW71 氯邻苯二酚 1,2-二加氧酶的底物。对于Pseudomonas putidaAC27 菌株双加氧酶和AcidovoraxPS14 菌株双加氧酶的Ki 都为 30 nM。 | |||
T10503 |
ACAT-IN-1 cis isomer
|
Acyltransferase | Metabolism |
ACAT-IN-1 cis isomer是一种有效的 ACAT 抑制剂(IC50:100 nM),可用于研究免疫系统相关疾病。 | |||
T35868 |
BCAT-IN-2
|
Others | Others |
BCAT-IN-2 是一种具有口服活性和选择性的线粒体支链氨基转移酶(BCATm)抑制剂,抑制 BCATm 和 BCATc,可用于肥胖症和血脂异常。 | |||
T38585 |
Tetrachlorocatechol
|
Others | Others |
Tetrachlorocatechol (TCC) 是一种氯化邻苯二酚化合物,是五氯苯酚的代谢产物。在纸浆生产的氯漂白过程中显著生成,并常见于牢固纸浆厂废水中检测到[1] [2]。TCC作为最有毒的氯化邻苯二酚之一而著称。 | |||
T6035 |
Odanacatib
奥达卡替,奥当卡替,MK-0822 |
Cysteine Protease | Proteases/Proteasome |
Odanacatib 是组织蛋白酶K(人/兔)的选择性抑制剂,IC50分别为0.2 nM 和 1 nM。 | |||
T41094 |
Wnt/β-catenin agonist 2
|
GSK-3; Wnt/beta-catenin | Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Stem Cells |
Wnt/β-catenin agonist 2激活 Wnt/β-catenin 信号传导,是一种有效的 Wnt 激动剂。 Wnt/β-catenin agonist 2可用于与信号转导相关的疾病研究,与癌症侵袭转移密切相关。 | |||
T4548 |
Procaterol hydrochloride
|
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Procaterol hydrochloride 用于治疗哮喘的短效β2-肾上腺素受体激动剂。 | |||
T6078 |
Saracatinib
AZD0530,塞卡替尼 |
EGFR; Src; BTK; Autophagy | Angiogenesis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Saracatinib (AZD0530) 是一种有效的 Src 抑制剂,抑制 c-Src、Lck、c-YES、Lyn、Fyn、Fgr 和 Blk 的 IC50值在 2.7 到 11 nM 之间,对其他酪氨酸激酶具有选择性。 | |||
T9988 |
Wnt/β-catenin agonist 3
|
Wnt/beta-catenin | Cytoskeletal Signaling; Stem Cells |
Wnt/β-catenin agonist 3是一种Wnt/beta-catenin 信号通路激动剂。 | |||
T60803 |
Wnt/β-catenin agonist 4
|
Wnt/beta-catenin | Cytoskeletal Signaling; Stem Cells |
Wnt/β-catenin agonist 4 是一种Wnt的激动剂,可激活Wnt/β-catenin信号,引导信号传输。 | |||
TP1730L |
β-catenin peptide acetate(265669-37-2 free base)
|
Others | Others |
β-catenin peptide acetate(265669-37-2 free base) 是一种由 Kb 呈递的天然存在的自身肽,可非常有效地介导 OT-I 胸腺细胞的阳性选择。 | |||
T2364 |
Tucatinib
ARRY-380,Irbinitinib,ONT-380 |
EGFR; HER | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Tucatinib (ONT-380) 是可口服的选择性HER2抑制剂,IC50为8 nM。 | |||
T37504L |
Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)
Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base) |
||
Cathepsin D and E FRET Substrate acetate 是组织蛋白酶 D 和 E 的荧光底物,但不适用于 B、H 或 L。Cathepsin D and E FRET Substrate acetate 可用于组织蛋白酶 D 和 E 研究的机理研究。 | |||
TP2058L |
Catestatin acetate
Catestatin acetate(142211-96-9 free base) |
Endogenous Metabolite; AChR | Metabolism; Neuroscience |
Catestatin acetate 是 nAChR 的非竞争性拮抗剂,可抑制儿茶酚胺的释放。 Catestatin acetate 调节心脏功能和血压。 | |||
T67884 |
β-catenin modulator IIa-661
|
Wnt/beta-catenin | Cytoskeletal Signaling; Stem Cells |
β-catenin modulator IIa-661是 Wnt 途径小分子抑制剂,具有抗肿瘤活性。 | |||
T77522 |
BCAT-IN-4
|
Others | Others |
BCAT-IN-4 是一种具有有效性的 BCAT 抑制剂 对 hBCATc 的 IC50 值为 2.35 μM。 BCAT-IN-4 具有抗癌活性,可用于研究胰腺导管腺癌。 | |||
T23109 |
3,5-Dinitrocatechol
|
Transferase | Metabolism |
3,5-Dinitrocatechol 是儿茶酚-O-甲基转移酶的有效抑制剂,IC50为 12 nM。它可用于制备钼 (VI)- 3,5-Dinitrocatechol 配合物。 | |||
T9696 |
β-catenin-IN-2
|
Wnt/beta-catenin | Cytoskeletal Signaling; Stem Cells |
β-catenin-IN-2 是有效的β-catenin 抑制剂。β-catenin-IN-2在结直肠癌中有研究的价值。 | |||
T1850 |
Balicatib
AAE581,巴利卡替 |
Cysteine Protease | Proteases/Proteasome |
Balicatib (AAE581) 是组织蛋白酶K 抑制剂,其对组织蛋白酶K 的抑制作用是组织蛋白酶B、L 和S 的抑制性的10到100倍。 | |||
T77555 |
3-Methoxycatechol
1,2-Dihydroxy-3-methoxybenzene |
Antiviral | Immunology/Inflammation |
3-Methoxycatechol 是一种木质素衍生的可再生化学品,可促进食管发生癌变。1,2-Dihydroxy-3-methoxybenzen 对脑脊髓炎病毒(EMCV)表现出很强的抗病毒活性. | |||
T1239 |
Indacaterol maleate
马来酸茚达特罗,QAB149 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Indacaterol maleate (QAB149) 是一种超长效的 β-肾上腺素受体激动剂。 | |||
T14044 |
4E2RCat
|
PERK | Apoptosis |
4E2RCat 是一种 eIF4E-eIF4G 相互作用的抑制剂,IC50为13.5 μM。 | |||
T62494 |
Cathepsin C-IN-5
|
||
CathepsinC-IN-5 (compound SF38) 为一高效、选择性、口服活性的组织蛋白酶 C (Cat C) 抑制剂,其针对Cat C、Cat L、Cat S、Cat B、Cat K 的IC50s 分别为 59.9 nM、4.26 µM、>5 µM、>5 µM、>5 µM。该化合物能够抑制骨髓和血液中的Cat C活性,降低中性粒细胞丝氨酸蛋白酶(NSP)的激活,并展现抗炎活性。 | |||
T64159 |
Cathepsin K inhibitor 2
|
||
Cathepsin K inhibitor 2 是一种 cathepsin K 的有效抑制剂。其中 Cathepsin K (Cat K) 是一种半胱氨酸蛋白酶,在 CTSK 基因调控下表达,与骨质疏松症密切相关,能够水解胶原蛋白。Cathepsin K inhibitor 2 对骨关节炎表现出研究潜力。 | |||
T63854 | Cathepsin C-IN-3 | ||
Cathepsin C-IN-3 是组织蛋白酶 C (Cat C) 的有效抑制剂 (IC50: 61.79 nM),也能抑制 THP-1 细胞 (IC50: 101.5 nM) 和 U937 细胞 (IC50: 86.5 nM)。 | |||
T62659 | Cathepsin C-IN-4 | ||
Cathepsin C-IN-4 是一种组织蛋白酶 C (Cat C) 的有效抑制剂 (IC50: 65.6 nM)。Cathepsin C-IN-4 对 THP-1 (IC50: 203.4 nM)和 U937 (IC50: 177.6 nM) 细胞具有抑制作用。 | |||
T125101 | 1,3-Diacetoxy-4,6,12-tetradecatriene-8,10-diyne | ||
1,3-Diacetoxy-4,6,12-tetradecatriene-8,10-diyne 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125101,CAS号为 29576-66-7。 | |||
T64620 | cataCXium A Pd G3 | ||
Methanesulfonato(diadamantyl-n-butylphosphino)-2'-amino-1,1'-biphenyl-2-yl)palladium(II) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64620。 | |||
T32157 |
Indocate
Indocatum,Indocato |
||
Indocate is a bioactive chemical. | |||
T40463 |
Relacatib
SB-462795 |
||
Relacatib (SB-462795) is a novel, potent, and orally active inhibitor of human cathepsins K, L, and V. It exhibits high affinity for these enzymes, with Ki values of 41 pM, 68 pM, and 53 pM, respectively. Moreover, Relacatib effectively inhibits endogenous cathepsin K in situ in human osteoclasts, as well as human osteoclast-mediated bone resorption, with IC 50 values of 45 nM and 70 nM, respectively. Additionally, in vitro studies demonstrate Relacatib's inhibitory effect on bone resorption in ... | |||
T27127 |
DCAT Maleate
DCAT |
||
DCAT Maleate is an inhibitor of N-methyl transferases (NMT). DCAT Maleate methylate non-methylated pre-neurotoxins to prevent the formation of Parkinson's syndrome neurotoxins. | |||
T72829 | β-catenin-IN-4 | ||
β-catenin-IN-4 是一种β-catenin 抑制剂,Ki 值为 0.64 μM。β-catenin-IN-4 降低 cyclin D1 和c-Myc 的蛋白表达水平。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN3609 |
Catalposide
Hydroxybenzoyl catalpol |
ERK; IL Receptor; TNF; NOS; NF-κB; NO Synthase; PPAR; Autophagy | Apoptosis; Autophagy; DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Metabolism; NF-κB |
Catalposide 是一种有效的 (HO)-1 诱导剂,从 Catalpa ovate G. Don(紫葳科)中分离出来。 Catalposide 具有抗氧化、抗细胞凋亡、抗微生物、抗肿瘤和抗炎特性。 | |||
TN7036 |
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide
(9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,间-甲氧基苄基-亚麻酰胺,Macamide Impurity 14 |
Wnt/beta-catenin | Cytoskeletal Signaling; Stem Cells |
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (Macamide Impurity 14) 是一种从玛卡中分离得到的玛卡酰胺。它能够激活典型的Wnt/β‐catenin 信号通路,诱导间充质干细胞成骨分化和随后的骨形成,可用于研究骨质疏松症。 | |||
TN1274 |
4-Allylcatechol
2-羟基胡椒酚,4-Allylpyrocatechol,Hydroxychavicol |
Others | Others |
4-Allylcatechol (Hydroxychavicol) 是合成黄樟素的一种中间体。 | |||
T2197 |
10-Deacetylbaccatin III
10-脱乙酰巴卡丁 III,10-脱乙酰基巴卡丁III |
Others | Others |
10-Deacetylbaccatin-III 是一种紫杉醇类似物制剂的中间体,具有抗癌活性。 | |||
T4779 |
4-Methylcatechol
p-Methylcatechol,3,4-二羟基甲苯,Homocatechol,4-methylbenzene-1,2-diol,3,4-Dihydroxytoluene |
Others; Endogenous Metabolite | Metabolism; Others |
4-Methylcatechol (3,4-Dihydroxytoluene) 是 p-toluate 的代谢物,它是 Catechol 2,3-Dioxygenase 的自杀性底物抑制剂。 | |||
T2988 |
(-)-Epigallocatechin Gallate
Epigallocatechol Gallate,(-)-表没食子儿茶素没食子酸酯,EGCG |
Ferroptosis; Reactive Oxygen Species; HIV Protease; Mitochondrial Metabolism; Endogenous Metabolite; Autophagy | Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome |
(-)-Epigallocatechin Gallate (EGCG) 是茶类黄酮,具有强大的抗氧化,抗炎和抗癌作用。它可抑制EGFR 信号传导,有抗癌作用。它是谷氨酸脱氢酶 1/2 抑制剂。它通过激活细胞色素c 氧化酶来诱导氧化磷酸化。 | |||
T2732 |
(-)-Epicatechin gallate
表儿茶素没食子酸酯,(−)-Epicatechin 3-gallate,Epicatechin gallate,(-)-Epicatechin 3-gallate,(-)-Epicatechin 3-O-gallate,ECG |
Virus Protease; COX; Autophagy | Autophagy; Immunology/Inflammation; Microbiology/Virology; Neuroscience |
(-)-Epicatechin gallate ((-)-Epicatechin 3-O-gallate) 抑制环加氧酶-1 的IC50值为 7.5 μM。 | |||
T3742 |
3-Methylcatechol
3-甲基苯邻二酚,3-Methylpyrocatechol,2,3-Toluenediol,3-甲基邻苯二酚,2,3-dihydroxytoluene |
Others | Others |
3-Methylcatechol (2,3-Toluenediol) 是由 Pseudomonas putidaMC2 产生,能够用作化学合成中的分子砌块。 | |||
T3845 |
(+)-Gallocatechin
Gallocatechol,没食子儿茶素没食子酸酯,D-Gallocatechin |
Others | Others |
(+)-Gallocatechin (Gallocatechol) 是一种从绿茶中获得的多酚类化合物,具有抗癌作用。 | |||
T2788 |
Baccatin III
巴卡亭 Ⅲ,浆果赤霉素III,Baccatin Ⅲ |
Others | Others |
Baccatin III (Baccatin Ⅲ) 是一种分离自太平洋紫杉树和其近缘种中的天然产物,能够减少 MDSCs 积累并抑制其功能,延缓肿瘤发展进程。 | |||
TN1608 |
(-)-Epigallocatechin-3-(3''-O-methyl) gallate
(-)-EGCG-3''-O-ME |
Antioxidant; Antibacterial | Microbiology/Virology; oxidation-reduction |
(-)-Epigallocatechin-3-(3''-O-methyl) gallate ((-)-EGCG-3''-O-ME) 是从茶叶中分离出的一种天然产物,具有很强的抗氧化、细胞毒性和抗菌活性,可增强蚀刻漂洗粘合剂与牙本质的粘合稳定性。 | |||
T2782 |
Catharanthine
(+)-3, 4-Didehydrocoronaridine,长春质碱,(+)-3,4-Didehydrocoronaridine |
Calcium Channel; AChR | Membrane transporter/Ion channel; Metabolism; Neuroscience |
Catharanthine ((+)-3,4-Didehydrocoronaridine) 是长春花中的一种生物碱,可抑制电压门控 L 型钙离子通道,具有抗肿瘤和降血压活性。 | |||
T3682 |
(-)-Catechin gallate
(-)-Catechin 3-O-gallate,儿茶素没食子酸酯,几茶素没食子酸酯,(-)-Catechin 3-gallate |
Others; COX | Immunology/Inflammation; Neuroscience; Others |
(-)-Catechin gallate ((-)-Catechin 3-O-gallate) 是绿茶儿茶素中的微量组分,可抑制COX-1和COX-2活性。它抑制人 Beta-secretase,对氯喹敏感的恶性疟原虫 NF54 和耐氯喹的恶性疟原虫 K1 具有抗疟原虫活性。 | |||
T3018 |
Protocatechualdehyde
Protocatechuic aldehyde,3,4-Dihydroxybenzaldehyde,Rancinamycin IV,Catechaldehyde,原儿茶醛 |
Reactive Oxygen Species; Antibacterial | Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB |
Protocatechualdehyde (3,4-Dihydroxybenzaldehyde),源自丹参根的天然多酚化合物,展现多样生物活性,并作为抗氧化剂、抗衰老剂、抗菌剂和抗炎剂在医药领域广泛应用。 | |||
T19229 |
Catalase
|
Others | Others |
Catalase 是重要的抗氧化酶,在清除 ROS 及维持氧化还原状态的平衡方面发挥着重要作用。Catalase 与肿瘤的发生,发展关系密切。有潜力用于肿瘤的预防研究。 | |||
TN6785 |
Dihydrocatalpol
(2S,3R,4S,5S,6R)-2-[[(1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-2,4,5,5a,6,6a-hexahydro-1bH-oxireno[5,6]cyclopenta[1,3-c]pyran-2-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol |
Others | Others |
Dihydrocatalpol ((2S,3R,4S,5S,6R)-2-[[(1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-2,4,5,5a,6,6a-hexahydro-1bH-oxireno[5,6]cyclopenta[1,3-c]pyran-2-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol) 是一种从地黄中提取的天然产物。 | |||
T13305 |
Viridicatol
|
Anti-infection; Antifungal | Microbiology/Virology |
Viridicatol 是从夹竹桃的内生真菌青霉菌属的发酵中分离出的一种喹诺酮类生物碱,对金黄色葡萄球菌有抗菌活性,MIC 值为 15.6 μg/mL。 | |||
T3023 |
Catharanthine sulfate
|
AChR | Neuroscience |
Catharanthine sulfate 抑制烟碱样受体介导的隔膜收缩。 | |||
T3013 |
Catharanthine tartrate
Catharanthine hemitartrate,酒石酸长春质碱 |
Others; Calcium Channel | Membrane transporter/Ion channel; Metabolism; Others |
Catharanthine tartrate (Catharanthine hemitartrate) 是长春花中的一种生物碱,可抑制电压门控 L 型钙离子通道,具有抗肿瘤和降血压活性。 | |||
TN6832 |
Sulcatone
6-甲基-5-庚烯-2-酮,6-methylhept-5-en-2-one,6-Methyl-5-hepten-2-one |
Endogenous Metabolite | Metabolism |
Sulcatone (6-Methyl-5-hepten-2-one) 是内源性代谢产物的一种。 | |||
T5132 |
9-dihydro-13-acetylbaccatin III
13-乙酰基-9-羟基巴卡丁 III,13-Acetyl-9-dihydrobaccatin III,9-DHAB III |
Apoptosis | Apoptosis |
9-dihydro-13-acetylbaccatin III (9-DHAB III) 是一种制备紫杉醇类似物的中间体。 | |||
T0822 |
Catechin
Catechinic acid,D-Catechin,(+)-Catechin,Cianidanol,儿茶素,Catechuic acid |
Apoptosis; Influenza Virus; COX; Endogenous Metabolite | Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience |
Catechin (Cianidanol) 是一种黄烷-3-醇,是一种天然酚类和抗氧化剂。它抑制环加氧酶-1,IC50为 1.4 μM。 | |||
T2987 |
(-)-Epigallocatechin
表没食子儿茶素,(-)-表没食子儿茶素,l-Epigallocatechin,Epigallocatechin,EGC |
MMP; Autophagy | Autophagy; Proteases/Proteasome |
(-)-Epigallocatechin (Epigallocatechin) 是绿茶中含量最丰富的黄酮类天然产物,可与未折叠的天然多肽结合,阻止转化为淀粉样蛋白原纤维。 | |||
T8255 |
(±)-Catechin
(±)-Catechin hydrate,儿茶素 |
ROS; COX | Immunology/Inflammation; Neuroscience |
(±)-Catechin ((±)-Catechin hydrate) hydrate 是 Catechin 的外消旋体,是从云南红豆杉中提取的一种天然产物,具有抗肿瘤、抗肥胖、抗糖尿病、抗心血管、抗感染、保肝和神经保护作用。 | |||
T8010 |
Dibutyl sebacate
Dibutyl decanedioate,癸二酸二丁酯 |
Others | Others |
Dibutyl sebacate (Dibutyl decanedioate) 是一种常作为塑料生产中的增塑剂的癸二酸二丁酯。 | |||
T0562 |
Protocatechuic acid
3, 4-Dihydroxybenzoic acid,3,4-二羟基苯甲酸,Protocatechuate,原儿茶酸,3,4-Dihydroxybenzoic acid |
Others | Others |
Protocatechuic acid (3, 4-Dihydroxybenzoic acid) 是天然的多酚类物质,具有神经保护活性。 | |||
T2780 |
Catalpol
梓醇,Catalpinoside,Digitalis purpurea L |
Others; HBV | Microbiology/Virology; Others |
Catalpol (Catalpinoside) 是一种在Rehmannia glutinosa 中发现的鸢尾花苷,具有神经保护、降血糖、抗癌、抗痉挛、抗氧化、抗HBV 和抗肝炎病毒作用。 | |||
TN7047 |
6-O-Methylcatalpol
|
Others | Others |
6-O-Methylcatalpol 是从 S. ningpoensis 的根中分离得到的天然产物。 | |||
T13597 |
(-)-Catechin
(-)-Catechuic acid,(-)-Cianidanol |
COX | Immunology/Inflammation; Neuroscience |
(-)-Catechin ((-)-Cianidanol) 是儿茶素的异构体,对环氧合酶-1(COX-1)有抑制作用,IC50为1.4 μM。 | |||
T2778 |
(+)-Catechin Hydrate
一水合儿茶素,(+)-水合儿茶素 |
Antioxidant; COX | Immunology/Inflammation; Neuroscience; oxidation-reduction |
(+)-Catechin hydrate 是来自茶树的抗氧化类黄酮,可抑制环加氧酶-1,IC50为 1.4 μM。它是一种自由基清除剂,可防止多种生物系统中自由基介导的损害。 | |||
T3807 |
(-)-Gallocatechin gallate
(-)-gallocatechin-3-O-gallate,(-)-Gallocatechol gallate,没食子儿茶素没食子酸酯,Gallocatechin gallate |
Others | Others |
(-)-Gallocatechin gallate ((-)-gallocatechin-3-O-gallate) 是一种从茶中分离出来的多酚,具有防癌活性。 它在 20 microM 时降低破骨细胞生成。 | |||
T4810 |
Pyrocatechuic acid
3-Hydroxysalicylic acid,2,3-二羟基苯甲酸,O-Pyrocatechuic acid,Catecholcarboxylic acid,NSC 27435,2,3-Dihydroxybenzoic acid |
Others; Endogenous Metabolite | Metabolism; Others |
Pyrocatechuic acid (Catecholcarboxylic acid) 是一种存在于血浆中的苯甲酸代谢物,当摄入阿司匹林后,它的含量会提高。 | |||
T3828 |
(-)-Gallocatechin
(2S,3R)-gallocatechin,(−)-GC,(-)-棓儿茶酸;没食子儿茶素,没食子儿茶素 |
Others | Others |
(-)-Gallocatechin ((−)-GC) 是一种 (-)-Epigallocatechin (EGC) 的差向异构体,常存在于各种茶产品中,具有抗氧化特性。 | |||
TN2540 |
1-Hydroxybaccatin I
|
Others | Others |
1-Hydroxybaccatin I 对对苯醌诱导的腹部收缩具有显着的镇痛活性。 | |||
T2856 |
(-)-Epicatechin
L-Epicatechin,表儿茶素,Epicatechin,(-)-Epicatechol,表儿茶精 |
Ferroptosis; COX; Endogenous Metabolite | Apoptosis; Immunology/Inflammation; Metabolism; Neuroscience |
(-)-Epicatechin (Epicatechin) 是一种 COX-1 的抑制剂,通过阻断 NF-κB 的 p65 亚基的核定位来抑制 IL-1β 诱导的 iNOS 表达。 | |||
T77563 |
4-Ethylcatechol
|
DNA | DNA Damage/DNA Repair |
4-Ethylcatechol 存在于红葡萄酒中,可从Glechoma longituba(NaKai)Kupr 中提取。4-Ethylcatechol 在Cu(II)存在下会引起DNA 损伤。4-Ethylcatechol 是一种高效的抗血小板化合物。 | |||
T2782L |
Catharanthine Tartrate(2468-21-5(free base))
|
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Catharanthine Tartrate(2468-21-5(free base)) 是从马达加斯加长春花中分离得到的天然产物,Catharanthine Tartrate 抑制电压操作的L 型Ca2+通道,具有抗癌和降血压活性。 | |||
TN2402 | Catalponol methylthiomethyl ether | Others | Others |
Catalponol methylthiomethyl ether is a natural product from plants | |||
T21159 |
Bis(2-ethylhexyl) sebacate
Di(2-ethylhexyl) Sebacate,Dioctyl Sebacate |
||
Bis(2-ethylhexyl) sebacate is used as a plasticizer in preparing ion-selective electrodes. It is an important raw material and intermediate used in organic synthesis, agrochemicals, pharmaceuticals and dyestuff fields. | |||
TN3189 |
6'-O-p-Hydroxybenzoylcatalposide
|
Others | Others |
6'-O-p-Hydroxybenzoylcatalposide是一种天然产物,属于紫葳科梓属,其产品编号为 TN3189,CAS号为 355143-38-3。6'-O-p-Hydroxybenzoylcatalposide可用作对照参考。 | |||
TN5725 |
Juncatrin A
1-(3,7-Dihydroxy-2,8-dimethyl-9,10-dihydrophenanthren-1-yl)ethanone |
||
Juncatrin A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5725,CAS号为 2265925-12-8。 | |||
TN2615 |
13-O-Cinnamoylbaccatin III
|
Others | Others |
13-O-Cinnamoylbaccatin III is a natural product from Taxus yunnanensis. | |||
TN4868 |
Pyrocatechol monoglucoside
|
Others | Others |
Pyrocatechol monoglucoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4868,CAS号为 2400-71-7。 | |||
TN4094 |
Gallocatechin gallate
|
IL Receptor; NF-κB; ROS; MAPK; PPAR; Fatty Acid Synthase | DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Metabolism; NF-κB |
Gallocatechin gallate has strong antioxidative, and anti-obesity activities, it inhibits 3T3-L1 differentiation and lipopolysaccharide induced inflammation through MAPK and NF-κB signaling; it also may have anti-diabetic effects by increasing sensitivity | |||
TN3251 |
7-Xylosyl-10-deacetylbaccatin III
|
Others | Others |
7-Xylosyl-10-deacetylbaccatin III is a natural product from Taxus brevifolia. | |||
TN3474 |
Baccatin IV
|
Others | Others |
Baccatin IV is a natural product from Taxus chinensis. | |||
TN3477 |
Baccatin VIII
|
Others | Others |
Baccatin VIII exhibits inhibitory effects on HL-60 and MCF-7, with IC50 values of 3.44 and 9.67 uM, respectively. | |||
TN2662 |
19-Hydroxybaccatin III
|
Others | Others |
19-Hydroxybaccatin III, 10-deacetylcephalomannine, and 10-deacetyltaxol are new antitumor taxanes from Taxus wallichiana. | |||
T38698 | Cathayanon H | ||
Cathayanon H, a compound derived from the paper mulberry tree, exhibits cytotoxicity against human ovarian carcinoma cells. | |||
TN4250 | Imbricatolic acid | p53 | Apoptosis |
Imbricatolic acid can prevent cell cycle progression in p53-null CaLu-6 cells. | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00764 |
Catalase/CAT Protein, Human, Recombinant
CAT,Catalase |
Human | E. coli |
Catalase (CAT) is a member of the catalase family. It exists as a homotetramer that occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Catalase is localized in the peroxisome. Catalase promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells, and normal and transformed fibroblast cells. Defects in CAT are the cause of acatalasemia which is characterized by absence of ... | |||
TMPY-02751 |
Cathepsin S Protein, Mouse, Recombinant (His)
cathepsin S,Cat S,Cats |
Mouse | HEK293 Cells |
Cathepsin S Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is AAB94925.1. | |||
TMPH-00345 |
Catalase Protein, Capsicum annuum, Recombinant (His)
CaCat1,Catalase,CAT |
Capsicum annuum | E. coli |
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Catalase Protein, Capsicum annuum, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 62.5 kDa and the accession number is Q9M5L6. | |||
TMPH-00080 |
Catalase-2 Protein, Arabidopsis thaliana, Recombinant (His & SUMO)
Catalase-2,CAT,CAT2 |
Arabidopsis thaliana | E. coli |
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Catalase-2 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 72.9 kDa and the accession number is P25819. | |||
TMPY-02464 |
Catalase/CAT Protein, Human, Recombinant (His)
catalase |
Human | Baculovirus Insect Cells |
Catalase is a ubiquitously expressed enzyme that catalyzes the decomposition of hydrogen peroxide to water and oxygen. It is a tetramer of four polypeptides chains containing four porphyrin heme groups that allow the enzyme to react with the hydrogen peroxide. The optimum PH of human catalase is approximately 7 and the optimum temperature is at 37 degree. Both the PH optimum and temperature for other catalases varies depending on the species. Catalase can be inhibited by a flux of O2-generated i... | |||
TMPU-00002 |
SOS1-Cat Protein, Human, Recombinant (His)
SOS-1,Son of sevenless homolog 1 |
Human | E. coli |
Defects in SOS1 are the cause of gingival fibromatosis 1 (GGF1) [MIM:135300]; also known as GINGF1. Gingival fibromatosis is a rare overgrowth condition. Defects in SOS1 are the cause of Noonan syndrome type 4 (NS4) [MIM:610733]. NS4 is an autosomal dominant disorder characterized by dysmorphic facial features, short stature, hypertelorism, cardiac anomalies, deafness, motor delay, and a bleeding diathesis. It is a genetically heterogeneous and relatively common syndrome, with an estimated incid... | |||
TMPY-01948 |
COQ7 Protein, Human, Recombinant (His)
CLK1,coenzyme Q7 homolog, ubiquinone (yeast),CAT5,C... |
Human | HEK293 Cells |
Ubiquinone biosynthesis protein COQ7 homolog, also known as Coenzyme Q biosynthesis protein 7 homolog, Timing protein clk-1 homolog and COQ7, is a mitochondrion inner membrane and peripheral membrane protein which belongs to theCOQ7 family. It is expressed dominantly in heart and skeletal muscle. COQ7 is synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. Th... | |||
TMPY-02869 |
MMP-12 Protein, Human, Recombinant (catalytic domain)
HME,ME,MMP-12,MME,matrix metallopeptidase 12 |
Human | E. coli |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ... | |||
TMPY-00735 |
Cathepsin S Protein, Human, Recombinant (His)
cathepsin S,MGC3886,CTSS |
Human | HEK293 Cells |
Cathepsin S Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37 kDa and the accession number is P25774-1. | |||
TMPY-02450 |
Cathepsin D Protein, Human, Recombinant (His)
HEL-S-130P,CLN10,cathepsin D,CPSD |
Human | HEK293 Cells |
Cathepsin D Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44 kDa and the accession number is P07339. | |||
TMPY-02205 |
Beta-Catenin Protein, Human, Recombinant (His & GST)
catenin beta 1,armadillo,CTNNB,MRD19,caten... |
Human | Baculovirus Insect Cells |
Beta-Catenin Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 113 kDa and the accession number is P35222-1. | |||
TMPY-00731 |
Cathepsin B Protein, Human, Recombinant (His)
APPS,cathepsin B,CPSB |
Human | HEK293 Cells |
Cathepsin B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.2 kDa and the accession number is A0A024R374. | |||
TMPH-00014 |
Abrin-c Protein, Abrus precatorius, Recombinant (His & Myc)
|
Abrus precatorius | E. coli |
The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. Abrin-a is more toxic than ricin.; The B chain is a galactose-specific lectin that facilitates the binding of abrin to the cell membrane that precedes endocytosis. Abrin-c Protein, Abrus precatorius, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight ... | |||
TMPH-02554 |
BCAT2 Protein, Mouse, Recombinant (His & Myc)
Bcat2,BCAT(m),Eca40,Branched-chain-amino-a... |
Mouse | E. coli |
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids. BCAT2 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 48.2 kDa and the accession number is O35855. | |||
TMPH-00514 |
Endo H Protein, Streptomyces plicatus, Recombinant (His)
Endoglycosidase H,Endo-beta-N-acetylglucosaminidase H,Endo H |
Streptomyces plicatus | P. pastoris (Yeast) |
Cleaves asparagine-linked oligomannose and hybrid, but not complex, oligosaccharides from glycoproteins. | |||
TMPH-03563 |
MCAT Protein, S. aureus, Recombinant (His)
|
Staphylococcus aureus | P. pastoris (Yeast) |
MCAT Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 35.6 kDa and the accession number is Q5HGK3. | |||
TMPH-01063 |
Cathepsin O Protein, Human, Recombinant (His & Myc)
CTSO1,CTSO,Cathepsin O |
Human | HEK293 Cells |
Proteolytic enzyme possibly involved in normal cellular protein degradation and turnover. Cathepsin O Protein, Human, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 28.5 kDa and the accession number is P43234. | |||
TMPH-00229 |
Cathelicidin-4 Protein, Bovine, Recombinant (His & SUMO)
Cathelicidin-4,Indolicidin,CATHL4 |
Bovine | E. coli |
Potent microbicidal activity; active against S.aureus and E.coli. Cathelicidin-4 Protein, Bovine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 17.9 kDa and the accession number is P33046. | |||
TMPH-00484 |
Cationic trypsin Protein, Canine, Recombinant (His & SUMO)
TRP1,Serine protease 1,PRSS1,TRY1,Pretrypsinogen I,Anionic t... |
Canine | E. coli |
Cationic trypsin Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPJ-01302 |
ACAT2 Protein, Human, Recombinant (His)
ACTL,Acetyl-CoA transferase-like protein,Acetyl-CoA acetyltr... |
Human | E. coli |
ACAT2 is a cytoplasmic enzyme which belongs to the thiolase family. ACAT2 takes part in lipid metabolism, lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. It is responsible for the synthesis of cholesteryl esters which are part of lipoproteins containing apoB. ACAT2 deficiency contributes to severe mental retardation and hypotonus. | |||
TMPJ-00472 |
Vitronectin Protein, Human, Recombinant (Truncated, His)
Vitronectin,Complement S-protein,Serum Spreading Factor,epib... |
Human | HEK293 Cells |
Vitronectin, also known as VTN, is a large glycoprotein found in blood and the extracellular matrix (ECM). Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood coagulation, fibrinolysis, pericellular proteolysis, complement dependent immune responses, and cell attachment and spreading. Blocking of Hic(a member of the pneumococcal surface protein C (PspC) family) by specific antiserum or genetic deletion significantly reduced pneumococca... | |||
TMPH-03483 |
Saxiphilin Protein, Aquarana catesbeiana, Recombinant (His)
|
Lithobates catesbeiana | HEK293 Cells |
Binds specifically to the neurotoxin saxitoxin. Its physiological role may be to transport or sequester an endogenous organic molecule other than Fe(3+). It may participate in a detoxification mechanism for neutralizing a microbial toxin. Saxiphilin Protein, Aquarana catesbeiana, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis-Myc tag. The predicted molecular weight is 43.7 kDa and the accession number is P31226. | |||
TMPY-00362 |
Cathepsin S Protein, Rat, Recombinant (His)
CTSS,Cathepsin S |
Rat | HEK293 Cells |
Cathepsin S Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa. | |||
TMPH-00012 |
Abrin-a Protein, Abrus precatorius, Recombinant (E. coli, His)
|
Abrus precatorius | E. coli |
The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. Abrin-a is more toxic than ricin.; The B chain is a galactose-specific lectin that facilitates the binding of abrin to the cell membrane that precedes endocytosis. Abrin-a Protein, Abrus precatorius, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 33.6... | |||
TMPH-00026 |
Catechol 1,2-dioxygenase Protein, Acinetobacter baylyi, Recombinant (His)
Equinatoxin-2,EqTII,DELTA-AITX-Aeq1a,Equinatoxin II,DELTA-ac... |
Actinia equina | E. coli |
Catechol 1,2-dioxygenase Protein, Acinetobacter baylyi, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.9 kDa and the accession number is P61914. | |||
TMPH-00058 |
asFP595 Protein, Anemonia sulcata, Recombinant (hFc)
GFP-like non-fluorescent chromoprotein FP595,asFP595 |
Anemonia sulcata | HEK293 Cells |
Pigment protein that is intensely purple in color. | |||
TMPH-03091 |
Silicatein Protein, Petrosia ficiformis, Recombinant (His & Myc)
|
Petrosia ficiformis | E. coli |
Polymerizes silica around the axial filament during spicule formation. Silicatein Protein, Petrosia ficiformis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.5 kDa and the accession number is Q6YD92. | |||
TMPY-00733 |
Cathepsin D Protein, Mouse, Recombinant (His)
CatD,CD,cathepsin D |
Mouse | HEK293 Cells |
Cathepsin D Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.4 kDa and the accession number is P18242. | |||
TMPY-04081 |
Cathepsin H Protein, Mouse, Recombinant (His)
cathepsin H,AL022844 |
Mouse | HEK293 Cells |
Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis. Cathepsin H Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.6 kDa and the accession number is AAA82966.1. | |||
TMPH-03261 |
Cathepsin D Protein, Rat, Recombinant (His & Myc)
Ctsd,Cathepsin D |
Rat | E. coli |
Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. Cathepsin D Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 45.2 kDa and the accession number is P24268. | |||
TMPK-00835 |
LCAT Protein, Mouse, Recombinant (His)
PAF acetylhydrolase,LCAT |
Mouse | HEK293 Cells |
Lecithin:cholesterol acyltransferase (LCAT) is the only enzyme capable of esterifying cholesterol in plasma, thus determining the maturation of high-density lipoproteins. Because it maintains an unesterified cholesterol gradient between peripheral cells and extracellular acceptors, for a long time, LCAT has been considered as a key enzyme in reverse cholesterol transport. | |||
TMPH-03263 |
Cathepsin Z Protein, Rat, Recombinant (His & SUMO)
Cathepsin Y,Ctsz,Cathepsin Z,Ctsy |
Rat | E. coli |
Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity. Capable of producing kinin potentiating peptides. | |||
TMPH-00056 |
Delta-AITX-Avd1c Protein, Anemonia sulcata, Recombinant (His)
ATX II,Delta-AITX-Avd1c,Toxin II,Delta-actitoxin-Avd1c,Neuro... |
Anemonia sulcata | P. pastoris (Yeast) |
Binds specifically to voltage-gated sodium channels (Nav) (site 3), thereby delaying their inactivation. Has a strong effect on crustaceans and insects (DmNav1) and a weaker effect on mammals. This toxin is highly potent at mammalian Nav1.1/SCN1A (EC(50)=6.01 nM) and Nav1.2/SCN2A (EC(50)=7.88 nM). It has also great activity on Nav1.5/SCN5A (EC(50)=49.05 nM), Nav1.4/SCN4A (EC(50)=109.49 nM) and Nav1.6/SCN8A (EC(50)=about 180 nM) and is less potent on Nav1.3/SCN3A (EC(50)=759.22 nM) (when measured... | |||
TMPY-00732 |
Cathepsin C Protein, Human, Recombinant (His)
DPP-I,PLS,JP,cathepsin C,CPPI,DPPI,PDON1,PALS,DPP1,... |
Human | HEK293 Cells |
Cathepsins are proteases found in many types of cells conserved in all animals, which have a vital role in mammalian cellular turnover such as bone resorption. The lysosomal cysteine protease Cathepsin C (CTSC), also known as dipeptidyl peptidase I (DPPI/DPP1), activates a number of granule-associated serine proteases with pro-inflammatory and immune functions by removal of their inhibitory N-terminal dipeptides. This lysosomal exo-cysteine protease belonging to the peptidase C1 family. Active c... | |||
TMPY-04503 |
Cathepsin B Protein, Rat, Recombinant (His)
cathepsin B |
Rat | HEK293 Cells |
Cathepsin B Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.1 kDa and the accession number is F7FAT8. | |||
TMPY-02985 |
Beta-Catenin Protein, Mouse, Recombinant (His & GST)
catenin β1,Bfc,Mesc,catenin beta 1,Cat... |
Mouse | Baculovirus Insect Cells |
Beta-Catenin Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 113 kDa and the accession number is Q02248. | |||
TMPY-02699 |
Cathepsin Z Protein, Human, Recombinant (His)
CTSX,cathepsin Z |
Human | HEK293 Cells |
Cathepsin Z Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33 kDa and the accession number is Q9UBR2. | |||
TMPH-03039 |
ASP2 Protein, Necator americanus, Recombinant (His)
Secreted protein ASP-2,Ancylostoma secreted protein 2,ASP2 |
Necator americanus | E. coli |
ASP2 Protein, Necator americanus, Recombinant (His) is expressed in E. coli. | |||
TMPH-00437 |
Cathepsin D Protein, Cricetulus griseus, Recombinant (His & SUMO)
Ctsd,Cathepsin D |
Chinese hamster | E. coli |
N/A. Cathepsin D Protein, Cricetulus griseus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 53.3 kDa and the accession number is G3I4W7. | |||
TMPH-00230 |
Cathelicidin-6 Protein, Bovine, Recombinant (His & SUMO)
CATHL6,Antibacterial peptide BMAP-27,Myeloid antiba... |
Bovine | E. coli |
Exerts a potent antimicrobial activity against Gram-negative and Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, and fungi. Cathelicidin-6 Protein, Bovine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 16.2 kDa and the accession number is P54228. | |||
TMPY-00736 |
Cathepsin Z Protein, Mouse, Recombinant (His)
AI787083,D2Wsu143e,CTSX,cathepsin Z,AU019819 |
Mouse | HEK293 Cells |
Cathepsin Z Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.2 kDa and the accession number is Q545I6. | |||
TMPH-01059 |
Cathepsin B Protein, Human, Recombinant (GST)
Cathepsin B1,APPS,Cathepsin B,CPSB,APP sec... |
Human | E. coli |
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis. Cathepsin B Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 54.6 kDa and the accession number is P07858. | |||
TMPY-04813 |
ACAT2 Protein, Rat, Recombinant (His)
acetyl-CoA acetyltransferase 2 |
Rat | E. coli |
Acyl-coenzyme A: cholesterol acyltransferase (ACAT) is an intracellular enzyme that produces cholesteryl esters in various tissues. In mammals, two ACAT genes (ACAT1 and ACAT2) have been identified. Together, these two enzymes are involved in storing cholesteryl esters as lipid droplets, in macrophage foam-cell formation, in absorbing dietary cholesterol, and in supplying cholesteryl esters as part of the core lipid for lipoprotein synthesis and assembly. The key difference in tissue distributio... | |||
TMPH-03262 |
Cathepsin K Protein, Rat, Recombinant (His)
CTSO,CTSO2,Cathepsin O2,Cathepsin X,Ca... |
Rat | E. coli |
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. | |||
TMPY-06479 |
Cathepsin H Protein, Human, Recombinant (His)
CPSB,ACC-5,minichain,ACC4,ACC5,cathepsin H,ACC-4 |
Human | HEK293 Cells |
Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis. Cathepsin H Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.62 kDa and the accession number is NP_004381.2. | |||
TMPH-00060 |
ApNPV Viral cathepsin Protein (His & Myc)
V-cath,Viral cathepsin,Cysteine proteinase... |
ApNPV | E. coli |
Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus. May participate in the degradation of foreign protein expressed by the baculovirus system. ApNPV Viral cathepsin Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.1 kDa and the accession number is Q91CL9. | |||
TMPH-02628 |
Cathepsin C Protein, Mouse, Recombinant (His & Myc)
Dipeptidyl transferase,Dipeptidyl peptidase I,Cathe... |
Mouse | E. coli |
Thiol protease. Has dipeptidylpeptidase activity. Can act as both an exopeptidase and endopeptidase. Can degrade glucagon. Plays a role in the generation of cytotoxic lymphocyte effector function. | |||
TMPH-00875 |
ACAT1 Protein, Human, Recombinant (His)
EC:2.3.1.9,MAT,Acetyl-CoA acetyltransferase, mitochondrial,A... |
Human | E. coli |
ACAT1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 45.0 kDa and the accession number is P24752. | |||
TMPH-03186 |
Metapyrocatechase Protein, Pseudomonas putida, Recombinant (His & Myc & SUMO)
|
Pseudomonas putida | E. coli |
N/A. Metapyrocatechase Protein, Pseudomonas putida, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 55.2 kDa and the accession number is P06622. | |||
TMPH-03564 |
MCAT Protein, S. aureus, Recombinant (His & SUMO)
|
Staphylococcus aureus | E. coli |
MCAT Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.6 kDa and the accession number is Q5HGK3. | |||
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