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248

抑制剂 & 化合物

23

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T14667	BLT-1	Others; HCV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	BLT-1 是一种氨基硫脲铜螯合剂，是一种选择性清除受体 B1 型 (SR-BI) 抑制剂，抑制高密度脂蛋白 (HDL) 和 SR-BI 介导的细胞之间的脂质转移。
T5326	Sugammadex sodium Org25969,Sugammadex (sodium),舒更葡糖钠	Others	Others
	Sugammadex sodium (Org25969) 是合成的 γ 环糊精衍生物，是一种新型的神经肌肉阻断逆转剂。
T0370	Pheniramine maleate Daneral,Inhiston,Trimetose,马来酸非尼拉敏	5-HT Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Pheniramine maleate (Trimetose) 是一种具有抗组胺和血管扩张特性的烷基胺衍生物，可与组胺 H1 受体结合，从而抑制磷脂酶 A2 和内皮源性松弛因子一氧化氮的产生。
T6134	IEM 1754 2HBr IEM 1754 dihydrobromide	GluR	Neuroscience
	IEM 1754 2HBr (IEM 1754 dihydrobromide) 是一种选择性 AMPA/红藻氨酸受体阻滞剂，作用于 GluR1 和 GluR3，IC50 为 6 μM。
T11063	DMT1 blocker 1	Others	Others
	DMT1 blocker 1 是二价金属转运蛋白1 (DMT1) 的阻断剂，IC50 为 0.64 μM，可以阻断体内肠细胞的铁摄取。
T11064	DMT1 blocker 2	Others	Others
	DMT1 blocker 2 是一种二价金属转运蛋白 1 的直接抑制剂(IC50:0.83 μM)。它可以阻断体内肠细胞的铁摄取。
T26078	Rhodblock 6 Rhodblock6,Rhodblock-6	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	Rhodblock 6 是一种 Rho 激酶 (ROCK) 抑制剂，可抑制磷酸化 MRLC（肌球蛋白调节轻链）定位,通过特异性抑制 Rho 激酶的活性发挥作用。
T12504	(+)-KCC2 blocker 1	Potassium Channel	Membrane transporter/Ion channel
	(+)-KCC2 blocker 1 是 KCC2 的选择性阻断剂 (IC50 = 0.4 μM)。
T8741	MitoBloCK-10 3-fluoro-N'-[(E)-(5-nitrothiophen-2-yl)m	Others	Others
	MitoBloCK-10 (3-fluoro-N'-[(E)-(5-nitrothiophen-2-yl)m) 是第一个能够减弱PAM 复合体活性的小分子调节剂，对 C 末端结构域的Tim44与前体和 Hsp70 结合具有抑制作用。
T8782	MitoBloCK-11 (MB-11)	Others	Others
	MitoBloCK-11 (MB-11) 是线粒体蛋白输入的小分子抑制剂，可能通过转运蛋白 Seo1 起作用，但不通过 Tom70 或 Tom20；抑制含有疏水片段的前体蛋白，以特定方式在缺乏尿嘧啶的培养基中促进生长，并影响斑马鱼的发育。
T10690	Cav 2.2 blocker 1	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Cav 2.2 blocker 1 是一种N 型钙离子通道 (Cav 2.2) 的阻断剂，IC50值为 1 nM，可用于治疗疼痛。
T60143	MitoBloCK-6	Apoptosis	Apoptosis
	MitoBloCK-6 是一种有效的Erv1/ALR 抑制剂，IC50分别为 900 nM 和 700 nM。MitoBloCK-6 还抑制Erv2，IC50值为1.4 μM。MitoBloCK-6 可通过释放细胞色素 c 诱导 hESCs 细胞凋亡。
T72170	NaV1.2/1.6 channel blocker-1	Sodium Channel	Membrane transporter/Ion channel
	NaV1.2/1.6 channel blocker-1 是一种有效的 NaV1.2/1.6 channel 阻滞剂，对 rNaV1.6 和 hNaV1.2 有抑制作用。NaV1.2/1.6 channel blocker-1 可用于研究全身性癫痫和运动障碍。
T12153	N-type calcium channel blocker-1	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	N-type calcium channel blocker-1 is an orally active analgesic agent,shows high affinity to functionally block N-type calcium channels.
T26077	Rhodblock 3
	Rhodblock 3 is a potent small molecule Rho pathway inhibitor.
T28132	NaV1.7 Blocker-801
	NaV1.7 Blocker-801 is a potent NaV1.7 blocker.
T69387	NMO-IgG blocker A-01
	NMO-IgG blocker A-01 is a idiotype-specific blocker of neuromyelitis opticaimmunoglobulin g (nmo-igg) binding to aquaporin-4 (aqp4)
TP2195	Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell	Others	Others
	Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell (Ac-Pro-Tyr-Asn-Ser-Ser-Pro-Arg-Pro-Glu-Gln-His-Lys-Ser-Tyr-Lys-Cys) is a peptide that inhibits the function of NOSs as a result it blocks the production of NO. Because of the invol
T80930	TRPV2-selective blocker 1
	TRPV2-selective blocker 1 (compound IV2-1) 为选择性TRPV2通道阻断剂，具有6.3 μM IC50，不对TRPV1、TRPV3和TRPV4通道产生影响。该化合物能够抑制巨噬细胞中TRPV2介导的Ca2+流入，进而抑制其吞噬功能。
T39717	VGSC blocker-1
	VGSC blocker-1 is a powerful small molecule that serves as a blocker for the neonatal isoform of the VGSC subtype known as Nav1.5 (nNav1.5). It effectively blocks INa peak currents by 34.9% at a concentration of 1 μM, and demonstrates a 0.3% inhibition of cell invasion at the same concentration in the MDA-MB-231 human breast cancer cell line, without compromising cell viability.
T11927	M2 ion channel blocker	Others	Others
	M2 ion channel blocker ,Antiviral agent, is capable of inhibiting and blocking the activity of M2 ion channel.
T62586	Cav 2.2/3.2 blocker 1
	Cav 2.2/3.2 blocker 1 (Compound 9e) 是一种神经钙离子通道 (neuronal calcium channel) 阻断剂，能够作用于 Cav2.2 (IC50: 1.22 μM) 和 Cav3.2 (IC50: 80 μM)。Cav 2.2/3.2 blocker 1 可以穿透中枢神经系统。
TP2485	difelikefalin acetate(1024828-77-0 Free base)	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	difelikefalin acetate 是酮体和砌块。
T4542	Clonixin Clonixic acid,氯尼辛	Others	Others
	Clonixin (Clonixic acid) 是一种非甾体抗炎药，具有口服活性。
T9160	4-Chloroquinolin-8-ol	Others	Others
	4-Chloroquinolin-8-ol 是一个组成部分。
T9537	N'-Nitro-D-arginine N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid,N'-硝基-D-精氨酸	Others	Others
	N'-Nitro-D-arginine (N'-Nitro-D-arginine) 是一种砌块。
T10101	Calcium channel-modulator-1	Others; Calcium Channel	Membrane transporter/Ion channel; Metabolism; Others
	Calcium channel-modulator-1是钙离子通道调节剂(IC50:0.8 μM)，具有阻塞主动脉收缩的专业化。
T50103	NFAT Inhibitor-2	Others	Others
	NFAT Inhibitor-2 是一种化学合成中的砌块。
T40020	Pomalidomide-C2-acid	Others	Others
	Pomalidomide-C2-acid 是 PROTAC 的组成部分。
T8361	Tetraethylammonium bromide 四乙基溴化铵,TEAB,TEA bromide	Potassium Channel	Membrane transporter/Ion channel
	Tetraethylammonium bromide (TEA bromide) 可以选择性阻断钾通道。
T27400L	Ganaplacide phosphate Ganaplacide phosphate (1261113-96-5 Free base)	Others	Others
	Ganaplacide phosphate 对疟原虫症状性无性血期感染具有多阶段抗疟活性，并且能够在动物模型中预防传播和阻断感染。
T34603	L-Selenocystine L-Selenocystine,L-硒代胱胺基乙酸	Others	Others
	L-Selenocystine (L-Selenocystine) 可用作生物活性硒醇化合物的组成部分。
T64341	H-β-Ala-AMC TFA	Others	Others
	H-β-Ala-AMC TFA 是氨基肽酶的底物之一。
T67830	p38α inhibitor 3	p38 MAPK	MAPK
	p38α inhibitor 3是一种丝裂原活化蛋白激酶P38α的抑制剂，可以有效阻断成肌细胞分化。
T22305	Dexrazoxane 右雷佐生,ICRF-187	Others	Others
	Dexrazoxane (ICRF-187) 是一种心脏保护剂。
T3543	NS-638 NS 638	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	NS-638 是一种 Ca2+ 通道阻滞剂，可阻断 K+ 刺激的细胞内 Ca2+ 升高，IC50值为3.4 μM。
T67910	2,4,5-Trichlorobenzenesulfonyl chloride	Others	Others
	2,4,5-Trichlorobenzenesulfonyl chloride (TCBSC) 是合成各种有机化合物(如胺、醇和羧酸)的通用构件。
T7470	6-Chloropurine 6-氯嘌呤,6-Chloro-9H-purine	Others	Others
	6-Chloropurine (6-Chloro-9H-purine) 是一种制备9-烷基嘌呤和6-巯基嘌呤的中间体，是化学合成的砌块，具有抗肿瘤作用。
T50099	HIF-2α-IN-4	Others; HIF/HIF Prolyl-Hydroxylase	Chromatin/Epigenetic; Metabolism; Others
	HIF-2a translation inhibitor 是一种有效的HIF-2α翻译抑制剂，IC50=5 μM，能够抑制组成型和缺氧诱导的 HIF-2α 蛋白表达。其中 HIF-2α-IN-4 将 5'UTR 铁响应元件与氧传感联系起来。
T5828	MS21570 5-(苄基硫代)-N-甲基-1,3,4-噻二唑-2-胺	GPR	Endocrinology/Hormones; GPCR/G Protein
	MS21570 作为 GPR171 拮抗剂基于其阻断能力，IC50 为 220 nM，可减少小鼠的焦虑样行为和恐惧条件反射。
T22353	Lanthanum(III) chloride heptahydrate	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Lanthanum(III) chloride heptahydrate 是一种无机化合物，用于生化研究，阻断二价阳离子通道，尤其是钙通道的活性。
TNU0864	HUP30	Potassium Channel; Calcium Channel	Membrane transporter/Ion channel; Metabolism
	HUP30是一种强效的血管舒张剂。HUP30可以刺激可溶性鸟苷酸环化酶，激活 K+离子通道，阻断细胞外 Ca2+的内流。
T50051	1,3-diethyl 2-(3-methoxyphenyl)propanedioate	Others	Others
	1,3-diethyl 2-(3-methoxyphenyl)propanedioate 是一种用作分子结构单元的化合物，可用于多种化合物的合成。
T9082	1,3-Benzoxazole-6-carboxylic acid	Others	Others
	1,3-Benzoxazole-6-carboxylic acid 被用作药物合成中的催化剂，以及其他化合物合成中的构建块。
T6762	AS1842856	Autophagy; FOXO1	Apoptosis; Autophagy
	AS1842856 是一种特异性的Foxo1抑制剂，IC50为 30 nM。它抑制自噬，直接与 FoxO1 结合而降低 FoxO1 的活性。
T4985	Neticonazole Hydrochloride	Antifungal	Microbiology/Virology
	Neticonazole hydrochloride 是一种咪唑衍生物，具有抗感染和抗癌作用。它也是一种长效抗真菌剂。
T7329	C-178	STING	Immunology/Inflammation
	C-178 是 STING 选择性共价抑制剂，与 Cys91 结合抑制小鼠中由不同的激活剂引起的 STING 反应。
T25212	CCCI-01 CCCI 01,CCCI01,Centrosome Clustering Chemical Inhibitor-01	Apoptosis	Apoptosis
	CCCI-01（Centrosome Clustering Chemical Inhibitor-01）是一种中心体簇抑制剂。 CCCI-01 具有抗癌活性，可诱导细胞凋亡，可用于阻断中心体聚类的非交叉耐药抗癌化合物的研究。
T4207	(S,R,S)-AHPC hydrochloride VHL Ligand 1 hydrochloride,ULM-1,Protein degrader 1 hydrochloride	Others; Ligand for E3 Ligase	Others; PROTAC
	(S,R,S)-AHPC hydrochloride (Protein degrader 1 hydrochloride) 是基于 VH032 的 VHL 配体，可用于募集 von Hippel-Lindau (VHL) 蛋白。它能够利用 linker 与靶蛋白配体连接，得到 PROTAC 分子。
T6074	KPT276 KPT-276,KPT 276	CRM1	Membrane transporter/Ion channel
	KPT276 (KPT 276) 是一种口服生物可利用的核输出选择性抑制剂(SINE)，不可逆地与 CRM1 结合并阻断 CRM1 的功能。

化合物

Cat.No: T14667

Target: Others, HCV Protease

Sugammadex sodium

Cat.No: T5326

Synonym: Org25969,Sugammadex (sodium),舒更葡糖钠

Target: Others

Pheniramine maleate

Cat.No: T0370

Synonym: Daneral,Inhiston,Trimetose,马来酸非尼拉敏

Target: 5-HT Receptor, Histamine Receptor

Cat.No: T6134

Synonym: IEM 1754 dihydrobromide

Target: GluR

DMT1 blocker 1

Cat.No: T11063

Target: Others

DMT1 blocker 2

Cat.No: T11064

Target: Others

Cat.No: T26078

Synonym: Rhodblock6,Rhodblock-6

Target: ROCK

(+)-KCC2 blocker 1

Cat.No: T12504

Target: Potassium Channel

Cat.No: T8741

Synonym: 3-fluoro-N'-[(E)-(5-nitrothiophen-2-yl)m

Target: Others

MitoBloCK-11 (MB-11)

Cat.No: T8782

Target: Others

Cav 2.2 blocker 1

Cat.No: T10690

Target: Calcium Channel

Cat.No: T60143

Target: Apoptosis

NaV1.2/1.6 channel blocker-1

Cat.No: T72170

Target: Sodium Channel

N-type calcium channel blocker-1

Cat.No: T12153

Target: Calcium Channel

Cat.No: T26077

NaV1.7 Blocker-801

Cat.No: T28132

NMO-IgG blocker A-01

Cat.No: T69387

Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell

Cat.No: TP2195

Target: Others

TRPV2-selective blocker 1

Cat.No: T80930

VGSC blocker-1

Cat.No: T39717

M2 ion channel blocker

Cat.No: T11927

Target: Others

Cav 2.2/3.2 blocker 1

Cat.No: T62586

difelikefalin acetate(1024828-77-0 Free base)

Cat.No: TP2485

Target: Opioid Receptor

Cat.No: T4542

Synonym: Clonixic acid,氯尼辛

Target: Others

4-Chloroquinolin-8-ol

Cat.No: T9160

Target: Others

N'-Nitro-D-arginine

Cat.No: T9537

Synonym: N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid,N'-硝基-D-精氨酸

Target: Others

Calcium channel-modulator-1

Cat.No: T10101

Target: Others, Calcium Channel

NFAT Inhibitor-2

Cat.No: T50103

Target: Others

Pomalidomide-C2-acid

Cat.No: T40020

Target: Others

Tetraethylammonium bromide

Cat.No: T8361

Synonym: 四乙基溴化铵,TEAB,TEA bromide

Target: Potassium Channel

Ganaplacide phosphate

Cat.No: T27400L

Synonym: Ganaplacide phosphate (1261113-96-5 Free base)

Target: Others

L-Selenocystine

Cat.No: T34603

Synonym: L-Selenocystine,L-硒代胱胺基乙酸

Target: Others

H-β-Ala-AMC TFA

Cat.No: T64341

Target: Others

p38α inhibitor 3

Cat.No: T67830

Target: p38 MAPK

Cat.No: T22305

Synonym: 右雷佐生,ICRF-187

Target: Others

Cat.No: T3543

Synonym: NS 638

Target: Calcium Channel

2,4,5-Trichlorobenzenesulfonyl chloride

Cat.No: T67910

Target: Others

Cat.No: T7470

Synonym: 6-氯嘌呤,6-Chloro-9H-purine

Target: Others

Cat.No: T50099

Target: Others, HIF/HIF Prolyl-Hydroxylase

Cat.No: T5828

Synonym: 5-(苄基硫代)-N-甲基-1,3,4-噻二唑-2-胺

Target: GPR

Lanthanum(III) chloride heptahydrate

Cat.No: T22353

Target: Calcium Channel

Cat.No: TNU0864

Target: Potassium Channel, Calcium Channel

1,3-diethyl 2-(3-methoxyphenyl)propanedioate

Cat.No: T50051

Target: Others

1,3-Benzoxazole-6-carboxylic acid

Cat.No: T9082

Target: Others

Cat.No: T6762

Target: Autophagy, FOXO1

Neticonazole Hydrochloride

Cat.No: T4985

Target: Antifungal

Cat.No: T7329

Target: STING

Cat.No: T25212

Synonym: CCCI 01,CCCI01,Centrosome Clustering Chemical Inhibitor-01

Target: Apoptosis

(S,R,S)-AHPC hydrochloride

Cat.No: T4207

Synonym: VHL Ligand 1 hydrochloride,ULM-1,Protein degrader 1 hydrochloride

Target: Others, Ligand for E3 Ligase

Cat.No: T6074

Synonym: KPT-276,KPT 276

Target: CRM1

Cat. No.	Product Name	Target	Signaling Pathways
T5275	2,5-Furandicarboxylic acid Dehydromucic Acid,2,5-Dicarboxyfuran,2,5-呋喃二甲酸	Others; Endogenous Metabolite	Metabolism; Others
	2,5-Furandicarboxylic acid (Dehydromucic Acid) 是重要的能够再生生物技术基础，能够在人类尿液中检测到，在聚酯生产中能够作为对苯二甲酸的环保替代品。
T3006	Cinnamylideneacetic acid Beta-Styrylacrylic acid,5-苯基戊烷-2,4-双酸,5-Phenyl-2,4-pentadienoic acid,5-Phenylpenta-2,4-dienoic acid	Others; Antibacterial	Microbiology/Virology; Others
	Cinnamylideneacetic acid (Beta-Styrylacrylic acid) 用作合成结构单元、抗疟疾剂。
T4896	D-Lyxose 来苏糖,D-(-)-Lyxose	Others; Endogenous Metabolite	Metabolism; Others
	D-Lyxose (D-(-)-Lyxose) 是内源性代谢产物的一种。
T8084	Dimethyl 4-hydroxyisophthalate 二甲基 4-羟基异邻苯二甲酸酯,Dimetghyl 4-Hydroxyisophthalate	Others	Others
	Dimethyl 4-hydroxyisophthalate (Dimetghyl 4-Hydroxyisophthalate) 是水杨酸甲酯类似物。
T19382	Isoguanine 2-羟基-6-氨基嘌呤,异鸟嘌呤	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Isoguanine 是一种嘌呤碱基，是鸟嘌呤的异构体，可作为有机合成的砌块。
T2A2476	L-Hydroxyproline 羟脯氨酸,trans-4-Hydroxy-L-proline,L-Hydroxyprolin,Trans-4-Hydroxyproline	Endogenous Metabolite	Metabolism
	L-Hydroxyproline (L-Hydroxyprolin) 是羟脯氨酸的异构体之一，是药物生产中有用的手性结构单元。
T5650	2,2':5',2''-Terthiophene alpha-三联噻吩,α-Terthienyl,Trithiophene	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	2,2':5',2''-Terthiophene (Trithiophene) 是杂环噻吩的低聚物，可用作有机合成的砌块。
T4842	1H-pyrazole 1,2-Diazole,Pyrazole,吡唑	Others; Endogenous Metabolite	Metabolism; Others
	1H-pyrazole (1,2-Diazole) 是内源性代谢产物的一种。
TN1828	Kahweol	Apoptosis; NF-κB; AMPK	Apoptosis; Chromatin/Epigenetic; NF-κB; PI3K/Akt/mTOR signaling
	Kahweol 是小果咖啡的成分之一，可诱导细胞凋亡，具有抗炎、抗血管生成和抗癌活性。它通过激酶的活化抑制的脂肪生成和增加葡萄糖摄取。
TMO2713	4(3H)-Quinazolinone Quinazolin-4-ol,4-Hydroxyquinazoline,4-羟基喹唑啉,4-Quinazolinol,4-Quinazolone,4-Quinazolinone	Antibacterial; Platelet aggregation	Microbiology/Virology; Others
	4(3H)-Quinazolinone (4-Hydroxyquinazoline) 是化学合成中的砌块，是一种生物活性氮杂环化合物。它具有多种生物学特性，如抗菌，抗真菌，抗惊厥，抗炎，抗 HIV，抗癌和缓解疼痛活性。
T3S1729	Dihydrolycorine	Others	Others
	Dihydrolycorine 是分离自Lycoris radiate 草药中，是一种真核细胞中蛋白质合成的抑制剂。
Fr16741	Oxindole 2-吲哚酮,板蓝根,Indolin-2-one	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Oxindole (Indolin-2-one) 是一种芳族杂环砌块，其衍生物是激酶抑制剂研究中的主要成分。
TN1275	p-Hydroxyphenethyl anisate 4-Hydroxyphenethylanisate	Others	Others
	p-Hydroxyphenethyl anisate (4-Hydroxyphenethylanisate) 是一种来自 Notopterygium forbe-siiBoiss 的天然产品，是一种新型聚合物缓释材料，与 AAPBA 嵌段共聚后，制备的纳米颗粒具有良好的 Ph 敏感性、葡萄糖敏感性、胰岛素负载速率和稳定性。
T2732	(-)-Epicatechin gallate 表儿茶素没食子酸酯,(−)-Epicatechin 3-gallate,Epicatechin gallate,(-)-Epicatechin 3-gallate,(-)-Epicatechin 3-O-gallate,ECG	Virus Protease; COX; Autophagy	Autophagy; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	(-)-Epicatechin gallate ((-)-Epicatechin 3-O-gallate) 抑制环加氧酶-1 的IC50值为 7.5 μM。
T6S1699	Shogaol [6]-Shogaol,姜烯酚,6-姜烯酚,6-Shogaol	Lipoxygenase; Autophagy	Autophagy; Metabolism
	6-Shogaol (6-Shogaol) 是从生姜中分离的一种天然产物，具有抗癌、抗炎和抗氧化的多种生物活性。
T5S1632	Barlerin 8-O-乙酰山栀苷甲酯,8-O-Acetylshanzhiside methyl ester,ND01	VEGFR; TNF; NF-κB; Akt; Caspase	Angiogenesis; Apoptosis; Cytoskeletal Signaling; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Tyrosine Kinase/Adaptors
	Barlerin (8-O-Acetylshanzhiside methyl ester) 是一种环孢菌素葡萄糖苷，从中国西藏民间药用植物中分离得到，能够抑制NF-κB 活性。
T12373	Paxilline	Others	Others
	Paxilline is an indole alkaloid mycotoxin from Penicillium paxilli, acts as a potent BK channels inhibitor by an almost exclusively closed-channel block mechanism. Paxilline possesses significant anticonvulsant activity.
T78503	Tropone
	Tropone作为分子构建块，在化学合成中具有重要应用。
T5614	3-Oxopentanedioic acid 1,3-丙酮二羧酸,1,3-Acetonedicarboxylic acid,3-Oxoglutaric acid	Endogenous Metabolite	Metabolism
	3-Oxopentanedioic acid (1,3-Acetonedicarboxylic acid) 是二羧酸，能够用作有机化学合成的中间体。
T8267	Aspartic acid calcium 天冬氨酸钙,Calcium L-aspartate,Aspartic acid (calcium)	Others	Others
	Aspartic acid calcium (Calcium L-aspartate) 是一种钙和 L-Aspartic acid (L-天冬氨酸) 连接的螯合物。其中L-Aspartic acid 是一种氨基酸，是体内蛋白质的结构单元。
T6981	1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid 1-甲基-6-氧代-1,6-二氢吡啶-3-羧酸,Nudifloric Acid	Others	Others
	1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid (Nudifloric Acid) 是来源于冬虫夏草，能够靶向阻断 AP-1 介导的荧光素酶活性，具有抗炎活性。其中冬虫夏草具有抗氧化，抗癌，抗炎，抗糖尿病，抗肥胖，抗血管生成和抗伤害感受活动。
TN4635	Neoechinulin A	NADPH-oxidase; Beta Amyloid; ASK; IκB/IKK; p38 MAPK; TNF; NOS; NF-κB; COX; Prostaglandin Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; MAPK; Neuroscience; NF-κB
	Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-ÎºB and p38 MAPK pathways, it may block the phosphorylation of mitogen-activated protein kinase (MAPK) molecule p38, apoptosis signal-regu
TN2775	2-Methoxystypandrone	MMP; BCL; IκB/IKK; GSK-3; TNF; NOS; NF-κB; Wnt/beta-catenin; COX; JAK; STAT	Angiogenesis; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; JAK/STAT signaling; Neuroscience; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-ÎºB signaling to limit the inflammation and oxidative stress for preservation of BBB integrity. 2-Methoxystypandrone concomitant

天然产物

2,5-Furandicarboxylic acid

Cat.No: T5275

Synonym: Dehydromucic Acid,2,5-Dicarboxyfuran,2,5-呋喃二甲酸

Target: Others, Endogenous Metabolite

Cinnamylideneacetic acid

Cat.No: T3006

Synonym: Beta-Styrylacrylic acid,5-苯基戊烷-2,4-双酸,5-Phenyl-2,4-pentadienoic acid,5-Phenylpenta-2,4-dienoic acid

Target: Others, Antibacterial

Cat.No: T4896

Synonym: 来苏糖,D-(-)-Lyxose

Target: Others, Endogenous Metabolite

Dimethyl 4-hydroxyisophthalate

Cat.No: T8084

Synonym: 二甲基 4-羟基异邻苯二甲酸酯,Dimetghyl 4-Hydroxyisophthalate

Target: Others

Cat.No: T19382

Synonym: 2-羟基-6-氨基嘌呤,异鸟嘌呤

Target: Nucleoside Antimetabolite/Analog

L-Hydroxyproline

Cat.No: T2A2476

Synonym: 羟脯氨酸,trans-4-Hydroxy-L-proline,L-Hydroxyprolin,Trans-4-Hydroxyproline

Target: Endogenous Metabolite

2,2':5',2''-Terthiophene

Cat.No: T5650

Synonym: alpha-三联噻吩,α-Terthienyl,Trithiophene

Target: Others, Antibacterial, Antibiotic

Cat.No: T4842

Synonym: 1,2-Diazole,Pyrazole,吡唑

Target: Others, Endogenous Metabolite

Cat.No: TN1828

Target: Apoptosis, NF-κB, AMPK

4(3H)-Quinazolinone

Cat.No: TMO2713

Synonym: Quinazolin-4-ol,4-Hydroxyquinazoline,4-羟基喹唑啉,4-Quinazolinol,4-Quinazolone,4-Quinazolinone

Target: Antibacterial, Platelet aggregation

Dihydrolycorine

Cat.No: T3S1729

Target: Others

Cat.No: Fr16741

Synonym: 2-吲哚酮,板蓝根,Indolin-2-one

Target: Others, HIV Protease

p-Hydroxyphenethyl anisate

Cat.No: TN1275

Synonym: 4-Hydroxyphenethylanisate

Target: Others

(-)-Epicatechin gallate

Cat.No: T2732

Synonym: 表儿茶素没食子酸酯,(−)-Epicatechin 3-gallate,Epicatechin gallate,(-)-Epicatechin 3-gallate,(-)-Epicatechin 3-O-gallate,ECG

Target: Virus Protease, COX, Autophagy

Cat.No: T6S1699

Synonym: [6]-Shogaol,姜烯酚,6-姜烯酚,6-Shogaol

Target: Lipoxygenase, Autophagy

Cat.No: T5S1632

Synonym: 8-O-乙酰山栀苷甲酯,8-O-Acetylshanzhiside methyl ester,ND01

Target: VEGFR, TNF, NF-κB, Akt, Caspase

Cat.No: T12373

Target: Others

Cat.No: T78503

3-Oxopentanedioic acid

Cat.No: T5614

Synonym: 1,3-丙酮二羧酸,1,3-Acetonedicarboxylic acid,3-Oxoglutaric acid

Target: Endogenous Metabolite

Aspartic acid calcium

Cat.No: T8267

Synonym: 天冬氨酸钙,Calcium L-aspartate,Aspartic acid (calcium)

Target: Others

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid

Cat.No: T6981

Synonym: 1-甲基-6-氧代-1,6-二氢吡啶-3-羧酸,Nudifloric Acid

Target: Others

Cat.No: TN4635

Target: NADPH-oxidase, Beta Amyloid, ASK, IκB/IKK, p38 MAPK, TNF, NOS, NF-κB, COX, Prostaglandin Receptor

2-Methoxystypandrone

Cat.No: TN2775

Target: MMP, BCL, IκB/IKK, GSK-3, TNF, NOS, NF-κB, Wnt/beta-catenin, COX, JAK, STAT

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