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561

抑制剂 & 化合物

201

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T2072	BET bromodomain inhibitor	Epigenetic Reader Domain	Chromatin/Epigenetic
	BET bromodomain inhibitor 是 BET 的一种有效抑制剂。
T10521	ODM-207 BET-IN-4,ODM207	Epigenetic Reader Domain	Chromatin/Epigenetic
	ODM-207 (BET-IN-4) 是一种 BET 溴区结构域蛋白的抑制剂，对 BRD4的 IC50值 ≤ 1 μM。
T9619	I-BET567
	I-BET567 是一种有效、具有口服活性的泛BET 候选抑制剂，对 BRD4 BD1 和 BD2 的pIC50s 分别为 6.9 和 7.2。I-BET567 在肿瘤和炎症的小鼠模型中已被证明有效。
T2120	I-BET151 GSK1210151A	Epigenetic Reader Domain	Chromatin/Epigenetic
	I-BET151 (GSK1210151A) 是 BRD2/3/4 的特异性 BET 抑制剂，IC50值分别为0.5、0.25、0.79 μM。
T39374	PROTAC BET Degrader-10
	PROTAC BET Degrader-10 (WO2017007612A1, example 37) is a highly efficient and selective small molecule compound designed to degrade BET protein BRD4. PROTAC BET Degrader-10 functions by utilizing specific ligands that connect Cereblon and BRD4, with a DC 50 value of 49 nM.
T10518	BET-BAY 002	Others	Others
	BET-BAY 002 is an effective BET inhibitor and exhibits efficacy in a multiple myeloma model.
T39998	BET bromodomain inhibitor 1
	BET bromodomain inhibitor 1 is an orally active, selective inhibitor of bromodomain and extra-terminal (BET) proteins. It specifically inhibits BRD4 with an IC50 of 2.6 nM. Additionally, BET bromodomain inhibitor 1 demonstrates high affinities towards BRD2(2), BRD3(2), BRD4(1), BRD4(2), and BRDT(2) with Kd values of 1.3 nM, 1.0 nM, 3.0 nM, 1.6 nM, and 2.1 nM, respectively. This compound exhibits anti-cancer activity.
T10522	BET-IN-6	Epigenetic Reader Domain	Chromatin/Epigenetic
	BET-IN-6 是一种有效且高亲和力的BRD2/BRD4抑制剂。BET-IN-6 是靶蛋白 BRD2/4 的配体，可用于合成 PROTAC BRD2/BRD4 degrader-1 。
T13850	PROTAC BET degrader-3	Epigenetic Reader Domain	Chromatin/Epigenetic
	PROTAC BET Degrader-3 is a potent degrader OF BET based on PROTAC.
T12559	PROTAC BET degrader-2	Others	Others
	PROTAC BET degrader-2 is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins (IC50 of 9.6 nM ).
T13849	PROTAC BET Degrader-1	Epigenetic Reader Domain	Chromatin/Epigenetic
	PROTAC BET Degrader-1 is a potent degrader of BET based on PROTAC.
T10520	BET-IN-2	Epigenetic Reader Domain	Chromatin/Epigenetic
	BET-IN-2 is a BET inhibitor (IC50: 52 nM for BRD4-BD1).
T10517	BET-BAY 002 (S enantiomer)	Others	Others
	BET-BAY 002 S enantiomer为BET-BAY 002的S型对映异构体，属于BET小分子抑制剂。
T12557	PROTAC BET-binding moiety 1	Others	Others
	PROTAC BET-binding moiety 1 is a key intermediate in the synthesis of high affinity BET inhibitors
T12558	PROTAC BET-binding moiety 2	Others	Others
	PROTAC BET-binding moiety 2 is an BET bromodomain inhibitor.
T1906	Molibresib GSK 525762A,GSK525762,(4S)-6-(4-氯苯基)-N-乙基-8-甲氧基-1-甲基-4H-[1,2,4]三唑并[4,3-a][1,4]苯并二氮杂卓-4-乙酰胺,I-BET 762	Epigenetic Reader Domain	Chromatin/Epigenetic
	Molibresib (GSK525762) 是一种 BET 溴结构域抑制剂，IC50为32.5在42.5 nM 之间。
T22845	I-BET151 dihydrochloride I-BET 151 hydrochloride	Others	Others
	I-BET 151 dihydrochloride is a BET bromodomain inhibitor that prevents BET from recruiting to chromatin.
T62055	NVS-BET-1
	NVS-BET-1 是 BET 溴结构域抑制剂。NVS-BET-1可以调节角质形成细胞可塑性。
T79610	BET-IN-17	Epigenetic Reader Domain	Chromatin/Epigenetic
	BET-IN-17（化合物16）作为BET家族的泛抑制剂，具有针对BETBD1和BETBD2的pIC50值，分别为7.8与7.6。
T63299	BET-IN-1
	BET-IN-1 是 BET 的有效的抑制剂，表现出良好的脑渗透性以及具有合理的代谢稳定性。
T62275	BET-IN-8
	BET-IN-8 (Compound 27) 是一种 BET 的有效抑制剂 (Ki: 0.83 μM, Kd: 0.571 μM)。BET-IN-8 能够改善体内 LPS 诱导的脓毒症。BET-IN-8 对脓毒症表现出研究潜力。
T61253	BET-IN-7
	BET-IN-7 (Compound 1) is a highly effective BET inhibitor, possessing a K i of 12.27 μM and a K d of 89.3 μM. It exhibits promising properties for sepsis-related research [1].
T78989	BET-IN-16	Epigenetic Reader Domain	Chromatin/Epigenetic
	BET-IN-16 (Comp I) 是一种BET抑制剂，展现出抗癌活性。BET-IN-16抑制前列腺癌细胞的生长，其对LNCaP和22Rv1细胞的IC50值分别为0.043 μM和0.034 μM。
T11472L	Molibresib besylate I-BET 762 besylate,GSK 525762C	CCR	Immunology/Inflammation; Microbiology/Virology
	Molibresib besylate is an inhibitor of BET bromodomain (IC50: 32.5-42.5 nM).
T79016	BET-IN-14	Epigenetic Reader Domain	Chromatin/Epigenetic
	BET-IN-14为一种泛BET抑制剂，展现口服活性（IC50：5.35 nM），并具备抗癌特性。
T6021	GSK1324726A I-BET726	Apoptosis; Epigenetic Reader Domain	Apoptosis; Chromatin/Epigenetic
	GSK1324726A (I-BET726) 是一种选择性有效的BET 蛋白抑制剂，高亲和力结合到BRD2、BRD3和BRD4，IC50值分别为 41 nM、31 nM 和 22 nM。
T70003	I-BET469
	I-BET469 is a Bromodomain and Extraterminal Inhibitor with a Low Predicted Human Dose.
T79527	BET BD2-IN-1	Epigenetic Reader Domain	Chromatin/Epigenetic
	BET BD2-IN-1（compound 45）为BETBD2选择性抑制剂，IC50值为1.6 nM，通过抑制STAT3与NF-κB活性，阻断Th17细胞的分化，适用于银屑病与炎症性肠病研究。
T61795	BET-IN-9
	BET-IN-9 是一种BET 抑制剂。
T79167	BET-IN-15	Epigenetic Reader Domain	Chromatin/Epigenetic
	BET-IN-15（化合物1）为一种有效的口服活性BET抑制剂，其对BRD4-BD1及BRD4-BD2的IC50分别为0.64 nM和0.25 nM，具有明显的抗增殖活性。
T72872	HDAC/BET-IN-1	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	HDAC/BET-IN-1表现出对HDAC1 (IC50= 0.163 μM) 和HDAC6 (IC50= 0.067 μM) 的亚微摩尔级别抑制作用，以及对BRD4 (Ki= 0.076 μM) 的抑制活性，同时也显示出显著的抗白血病活性。
T79084	BET bromodomain inhibitor 3	Epigenetic Reader Domain	Chromatin/Epigenetic
	BET bromodomain inhibitor 3为BET溴区结构域抑制剂，对BrdT抑制作用显示Ki值高于40 µM，适用于避孕、癌症和心脏病相关研究。
T62655	BET bromodomain inhibitor 2
	BET bromodomain inhibitor 2 是一种 BET 型溴化域的有效抑制剂 (IC50: 14.1 μM)。
T6828	ZL0420	Epigenetic Reader Domain	Chromatin/Epigenetic
	ZL0420 是有效且选择性的 BET 溴结构域 4 (BRD4) 抑制剂，对 BRD4 的溴结构域 (BD) 具有纳摩尔结合亲和力。ZL0420 对 BRD4 BD1和 BRD4 BD2 的IC50分别为 27 nM 和 32 nM。
T6859	I-BRD9 GSK602	Epigenetic Reader Domain	Chromatin/Epigenetic
	I-BRD9 (GSK602) 是一种选择性的 BRD9 细胞抑制剂，pIC50 为 7.3。
T17881	(S,R,S)-AHPC-C10-NH2 VH032-C10-NH2	Others; Ligand for E3 Ligase	Others; PROTAC
	(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) 包含基于 (S,R,S)-AHPC 的VHL 配体和 1 个 linker，是一种合成的 E3 连接酶配体-linker 偶联物 (E3 ligase ligand-linker conjugate)。用于 BET 的靶向 PROTAC 的合成。
T73390	I-BET432
	I-BET432 是一种BET 抑制剂。I-BET432 抑制BRD4的 N 端溴化域 (BD1) 和 C 端溴化域 (BD2) 的pIC50值分别为 7.5 和 7.2。I-BET432 可作为多种肿瘤和炎症疾病研究的口服候选分子。
T63858	I-BET282E
	I-BET282E 是八种 BET bromodomains 泛抑制剂，对其他代表性含溴代烷的蛋白质表现出选择性。I-BET282E 能够作用于 8 种 BRD2 (BD1/BD2), BRD2 (BD1/BD), BRD3 (BD1/BD), BRD4 (BD1/BD) ，他们的 pIC50值为 6.4-7.7。
T40031	Thalidomide-O-C6-NH2 hydrochloride 4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride,萨力多胺-O-C6-氨基盐酸盐	E3 Ligase Ligand-Linker Conjugate	PROTAC
	Thalidomide-O-C6-NH2 hydrochloride (4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride) 是一种合成的E3 连接酶配体 -linker 偶联物，用于 PROTAC dTAG-13 的合成。其中 dTAG-13 是一种 FKBP12F36V 和 BET 的降解剂。
T13086	I-BET762 carboxylic acid Molibresib carboxylic acid,PROTAC BRD4-binding moiety 2,GSK525762A carboxylic acid	Epigenetic Reader Domain	Chromatin/Epigenetic
	I-BET762 carboxylic acid is an inhibitor of BRD4(pIC50 of 5.1).
T18661	(S,R,S)-AHPC-C10-NH2 dihydrochloride VH032-C10-NH2 dihydrochloride,VH032-linker 10,(S,R,S)-AHPC-C10-NH2二盐酸盐,VH032 amide-alkylC10-amine	Others; Ligand for E3 Ligase	Others; PROTAC
	(S,R,S)-AHPC-C10-NH2 dihydrochloride (VH032-linker 10) 包含基于 (S,R,S)-AHPC 的VHL 配体和 1 个 linker，是一种合成的 E3 连接酶配体-linker 偶联物，用于合成 BET 的靶向 PROTAC。
T5130	dBET6	Apoptosis; Epigenetic Reader Domain	Apoptosis; Chromatin/Epigenetic
	dBET6 是一种基于 PROTAC 的选择性和细胞渗透性 BET 降解剂，IC50值为 14 nM。它具有抗肿瘤活性。
T4495	dBET1	Epigenetic Reader Domain	Chromatin/Epigenetic
	dBET1 是一种由 BRD4 抑制剂 JQ1 与 NSC 527179 衍生物通过 linker 产生的 PROTAC，可诱导 BRD4 降解。它是由Cereblon 配体和BRD4配体相连的PROTAC，其EC50值为 430 nM。
T2480	Apabetalone RVX-208,RVX000222,阿帕他隆	Epigenetic Reader Domain; HIV Protease	Chromatin/Epigenetic; Microbiology/Virology; Proteases/Proteasome
	Apabetalone (RVX000222) 是一种 BET 溴结构域抑制剂，用于研究治疗糖尿病、动脉粥样硬化和冠状动脉疾病。
T14550	BETd-260 ZBC 260	Epigenetic Reader Domain	Chromatin/Epigenetic
	BETd-260是一种 PROTAC，由 Cereblon 配体和 BET 配体相连，对白血病细胞株 BRD4蛋白的抑制作用。
T1163	Betamethasone valerate Betnovate,倍他米松戊酸酯,Betaderm,Betamethasone 17-valerate,Luxiq	Glucocorticoid Receptor	Endocrinology/Hormones
	Betamethasone valerate (Luxiq) 的 17 戊酸酯，是一种具有抗炎活性的局部皮质类固醇。它能够抑制放射标记的糖皮质激素地塞米松与人表皮(IC50:5 nM)及小鼠皮肤(IC50:6 nM)的结合。它可用于研究复发性口疮。
T0028	Gamibetal 3-Hydroxy-GABA,4-氨基-3-羟基丁酸,4-Amino-3-hydroxybutyric Acid	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Gamibetal (4-Amino-3-hydroxybutyric Acid) 是 γ-氨基-β-羟基丁酸，对癫痫具有潜在的研究价值。
TNU0758	2-Aminopurine-9-beta-D-(2’-deoxy)riboside	Others	Others
	2-Aminopurine-9-beta-D-(2’-deoxy)riboside 是2-Aminopurine 的衍生物。
T60017	5-Bromo-4-chloro-3-indoxyl-beta-D-cellobioside	Others	Others
	5-Bromo-4-chloro-3-indoxyl-beta-D-cellobioside 是用于检测纤维生物水解酶的显色化合物。
T76743	Emibetuzumab LY2875358	c-Met/HGFR	Tyrosine Kinase/Adaptors
	Emibetuzumab 是一种有效的人源化二价 MET 抗体 (IgG4 型)。Emibetuzumab 具有抗肿瘤活性，对 HGF 依赖性和非依赖性 MET 通路的激活和肿瘤生长有抑制作用可用于研究晚期去势抵抗性前列腺癌。

化合物

BET bromodomain inhibitor

Cat.No: T2072

Target: Epigenetic Reader Domain

Cat.No: T10521

Synonym: BET-IN-4,ODM207

Target: Epigenetic Reader Domain

Cat.No: T9619

Cat.No: T2120

Synonym: GSK1210151A

Target: Epigenetic Reader Domain

PROTAC BET Degrader-10

Cat.No: T39374

Cat.No: T10518

Target: Others

BET bromodomain inhibitor 1

Cat.No: T39998

Cat.No: T10522

Target: Epigenetic Reader Domain

PROTAC BET degrader-3

Cat.No: T13850

Target: Epigenetic Reader Domain

PROTAC BET degrader-2

Cat.No: T12559

Target: Others

PROTAC BET Degrader-1

Cat.No: T13849

Target: Epigenetic Reader Domain

Cat.No: T10520

Target: Epigenetic Reader Domain

BET-BAY 002 (S enantiomer)

Cat.No: T10517

Target: Others

PROTAC BET-binding moiety 1

Cat.No: T12557

Target: Others

PROTAC BET-binding moiety 2

Cat.No: T12558

Target: Others

Cat.No: T1906

Synonym: GSK 525762A,GSK525762,(4S)-6-(4-氯苯基)-N-乙基-8-甲氧基-1-甲基-4H-[1,2,4]三唑并[4,3-a][1,4]苯并二氮杂卓-4-乙酰胺,I-BET 762

Target: Epigenetic Reader Domain

I-BET151 dihydrochloride

Cat.No: T22845

Synonym: I-BET 151 hydrochloride

Target: Others

Cat.No: T62055

Cat.No: T79610

Target: Epigenetic Reader Domain

Cat.No: T63299

Cat.No: T62275

Cat.No: T61253

Cat.No: T78989

Target: Epigenetic Reader Domain

Molibresib besylate

Cat.No: T11472L

Synonym: I-BET 762 besylate,GSK 525762C

Target: CCR

Cat.No: T79016

Target: Epigenetic Reader Domain

Cat.No: T6021

Synonym: I-BET726

Target: Apoptosis, Epigenetic Reader Domain

Cat.No: T70003

Cat.No: T79527

Target: Epigenetic Reader Domain

Cat.No: T61795

Cat.No: T79167

Target: Epigenetic Reader Domain

HDAC/BET-IN-1

Cat.No: T72872

Target: HDAC

BET bromodomain inhibitor 3

Cat.No: T79084

Target: Epigenetic Reader Domain

BET bromodomain inhibitor 2

Cat.No: T62655

Cat.No: T6828

Target: Epigenetic Reader Domain

Cat.No: T6859

Synonym: GSK602

Target: Epigenetic Reader Domain

(S,R,S)-AHPC-C10-NH2

Cat.No: T17881

Synonym: VH032-C10-NH2

Target: Others, Ligand for E3 Ligase

Cat.No: T73390

Cat.No: T63858

Thalidomide-O-C6-NH2 hydrochloride

Cat.No: T40031

Synonym: 4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride,萨力多胺-O-C6-氨基盐酸盐

Target: E3 Ligase Ligand-Linker Conjugate

I-BET762 carboxylic acid

Cat.No: T13086

Synonym: Molibresib carboxylic acid,PROTAC BRD4-binding moiety 2,GSK525762A carboxylic acid

Target: Epigenetic Reader Domain

(S,R,S)-AHPC-C10-NH2 dihydrochloride

Cat.No: T18661

Synonym: VH032-C10-NH2 dihydrochloride,VH032-linker 10,(S,R,S)-AHPC-C10-NH2二盐酸盐,VH032 amide-alkylC10-amine

Target: Others, Ligand for E3 Ligase

Cat.No: T5130

Target: Apoptosis, Epigenetic Reader Domain

Cat.No: T4495

Target: Epigenetic Reader Domain

Cat.No: T2480

Synonym: RVX-208,RVX000222,阿帕他隆

Target: Epigenetic Reader Domain, HIV Protease

Cat.No: T14550

Synonym: ZBC 260

Target: Epigenetic Reader Domain

Betamethasone valerate

Cat.No: T1163

Synonym: Betnovate,倍他米松戊酸酯,Betaderm,Betamethasone 17-valerate,Luxiq

Target: Glucocorticoid Receptor

Cat.No: T0028

Synonym: 3-Hydroxy-GABA,4-氨基-3-羟基丁酸,4-Amino-3-hydroxybutyric Acid

Target: HIV Protease

2-Aminopurine-9-beta-D-(2’-deoxy)riboside

Cat.No: TNU0758

Target: Others

5-Bromo-4-chloro-3-indoxyl-beta-D-cellobioside

Cat.No: T60017

Target: Others

Cat.No: T76743

Synonym: LY2875358

Target: c-Met/HGFR

Cat. No.	Product Name	Target	Signaling Pathways
T14001	11-Beta-hydroxyandrostenedione 4-雄烯-11β-醇-3,17-二酮,NSC-17102,4-Androsten-11β-ol-3,17-dione	Endogenous Metabolite	Metabolism
	11-Beta-hydroxyandrostenedione (NSC-17102) 是主要存在于肾上腺的类固醇，也是 11β-羟基类固醇脱氢酶同工酶抑制剂。随着 4-androstenedione 的提高，通过测量血浆中的11-Beta-hydroxyandrostenedione，能够区分高雄激素血症的肾上腺或卵巢起源。
TN6600	Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside 是一种吡喃葡萄糖苷，对 HIV-2 RNase H 具有抑制作用，IC50 为 5.19 μM。
T4S1439	6'-O-beta-D-Glucosylgentiopicroside 6'-O-β-D-葡萄糖基龙胆苦苷,6'-O-Glucosylgentiopicroside	Antifungal	Microbiology/Virology
	6'-O-beta-D-Glucosylgentiopicroside (6'-O-Glucosylgentiopicroside) 是一种环烯醚萜，分离自G. straminea 根中。它能显著抑制 fMLP 诱导的超氧化物生成。
TN1260	3-O-beta-D-Glucopyranosylplatycodigenin	Others	Others
	3-O-Beta-D-Glucopyranosylplatycodigenin 是分离自桔梗根的一种齐墩果烷型三萜类化合物。它具有抗 HSC-T6 细胞增殖活性，IC50为 13.36 μM。
T2S1792	Lycobetaine 石蒜内胺,Ungeremine,石蒜醋胺,石蒜碱内铵盐	Antibacterial	Microbiology/Virology
	Lycobetaine (Ungeremine) 是一种潜在的抗罗克福尔青霉和黑曲霉的生物杀菌剂。它对柱状黄杆菌有很强的抗菌活性。它有效地靶向哺乳动物以及细菌I 型和II 型拓扑异构酶。它显示出强烈的乙酰胆碱酯酶抑制活性（IC(50) 值为 0.35 microM）。它具有抗原生动物活性，在体外试验中对Trypanosoma brucei rhodesiense、T. cruzi 表现出良好的活性。
TN1258	3-Acetyl-beta-boswellic acid 3-O-Acetyl-beta-boswellic acid,3-乙酰基-BETA-乳香酸	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	3-Acetyl-beta-boswellic acid 是一种乳香酸，分离自乳香锯缘胶树脂。
T5S0018	Betulonic acid 路路通酸,(+)-Betulonic acid,Betunolic acid,Liquidambaric acid	Parasite; HSV	Microbiology/Virology
	Betulonic acid (Liquidambaric acid) 是一种在许多植物中存在的三萜类天然产物，具有抗肿瘤，抗炎，抗寄生虫和抗病毒的活性。
TN1019	Beta-mangostin β-Mangostin,beta-倒捻子素	Apoptosis; Antibacterial; Parasite	Apoptosis; Microbiology/Virology
	Beta-mangostin (β-Mangostin) 是存在 Cratoxylum arborescens 中的一种氧杂蒽酮类天然产物，有抗癌和抗菌活性，对结核分枝杆菌的 MIC 值为 6.25 μg/mL。它在体外有抗疟活性，对恶性疟原虫的 IC50值为 3.00 μg/mL。
T0019	Betaine chloride Betaine hydrochloride,盐酸甜菜碱	Others; Chloride channel; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism; Others
	Betaine chloride (Betaine hydrochloride) 是一种天然化合物，在许多食物中能够发现，也是能够维持正常 DNA 甲基化模式的特性甲基供体。
T2830	Betulinic acid 白桦脂酸,桦木酸,ALS-357,Lupatic acid,Betulic acid	Apoptosis; Mitophagy; NF-κB; HIV Protease; Topoisomerase; Endogenous Metabolite; Aminopeptidase; Autophagy	Apoptosis; Autophagy; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	Betulinic acid (ALS-357) 是从白桦树皮中分离出来的一种五环三萜类天然产物，是真核细胞拓扑异构酶 I 的抑制剂，IC50值为 5 μM，具有抗逆转录病毒、抗疟疾、抗癌和抗炎特性。
T3825	Lobetyolin Praeruptorin D,党参炔苷	Others	Others
	Lobetyolin (Praeruptorin D) 是党参衍生的具有抗氧化作用的化合物。
T3121	Betulin Trochol,betulinic alcohol,betuline,betulinol,桦木醇,Betulol,白桦脂醇	Apoptosis; Endogenous Metabolite; Lipid; Fatty Acid Synthase	Apoptosis; Metabolism
	Betulin (betulinol) 是从桦树树皮中分离出来的一种天然三萜，是 SREBP 抑制剂。
T8846	beta-Escin B-escin,AESCINE,beta-七叶素	Immunology/Inflammation related	Immunology/Inflammation
	beta-Escin 是七叶树种子的主要活性成分。它可抑制碱性成纤维细胞生长因子所诱导的增殖、迁移、管形成以及体内 CAM 血管生成。它具有研究抗血管生成作用的分子机制的潜力。
TN1255	3-O-Acetyl-11-hydroxy-beta-boswellic acid	Lipoxygenase	Metabolism
	3-O-Acetyl-11-hydroxy-beta-boswellic acid 是 5-脂氧合酶抑制剂。
T13092	Tauro-Obeticholic acid	FXR	Metabolism
	Tauro-Obeticholic acid 是一种牛磺酸的特性代谢物。Obeticholic Acid 是口服具有活性的法尼样 X 受体激动剂。
T2966	Beta-Sitosterol Cupreol,谷甾醇,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,beta-谷甾醇,22,23-Dihydrostigmasterol,Betaprost	Apoptosis; Lipase; Endogenous Metabolite	Apoptosis; Metabolism
	Beta-Sitosterol (SKF 14463) 是一种植物甾醇，干扰细胞周期、细胞凋亡、增殖、存活、侵袭、血管生成和炎症等多种细胞信号通路。
TN4931	(S)-(-)-beta-Citronellol	Others	Others
	(S)-(-)-beta-Citronellol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4931，CAS号为 7540-51-4。
TQ0070	Luteolin-3-O-beta-D-glucuronide	Others	Others
	Luteolin-3-O-beta-D-glucuronide 是木犀草素葡萄糖醛酸，木犀草素的 3’ 端位置有 β-d-葡萄糖苷酸残基。
TN7212	Acacetin-7-O-beta-D-galactopyranoside	Others	Others
	Acacetin-7-O-beta-D-galactopyranoside 是一种天然产物，存在于野菊花 Chrysanthemum indicum。
TN4674	Nortrachelogenin-8'-O-beta-glucoside	Others	Others
	Nortrachelogenin-8'-O-beta-glucoside 是一种具有二芳基羟基丁内酯骨架的木脂素，其分离自 Trachelospermum jasminoides (Lindl.) Lem 的叶和茎。
T3S0208	Hederagenin 28-O-beta-D-glucopyranosyl ester Hederagenin-28-beta-D-glucopyranoside,常春苷元-28-BETA-D-吡喃葡萄糖苷,常春藤皂苷元28-O-beta-D-吡喃葡萄糖酯	Others	Others
	Hederagenin-28-beta-D-glucopyranoside 是一种分离自 Ilex cornuta 中的三萜皂苷，能够保护H2O2诱导的心肌细胞免于损伤。
T5713	2"-O-beta-L-galactopyranosylorientin 荭草素-2"-0-B-L半乳糖苷,荭草素-2"-O-BETA-L-半乳糖苷,2''-O-β-L-Galorientin	Others	Others
	2"-O-beta-L-galactopyranosylorientin (2''-O-β-L-Galorientin) 提取自Trollius ledebouri 的花朵。它是多药耐药蛋白2 (MRP2) 的底物，能够被动扩散，并涉及转运蛋白介导的外排作用。
T3243	Betaine Abromine,glycine betaine,oxyneurine,trimethylglycine,lycine,甜菜碱	Others; Endogenous Metabolite	Metabolism; Others
	Betaine (trimethylglycine) 是许多食物中发现的天然化合物，也是能够维持正常 DNA 甲基化模式的特性甲基供体。它广泛存在于植物，动物，微生物和丰富的膳食来源中。它能够促进各种肠道微生物抵抗渗透变化，从而改善微生物发酵特性。它也能够作为渗透物，通过防止脱水和渗透失活来维持禽类的细胞水和离子平衡，从而提高禽类对热应激的能力。
T8166	Pennogenin 3-O-beta-chacotrioside 偏诺皂苷元-3-O-Α-L-吡喃鼠李糖-(1→4)[Α-L-吡喃鼠李糖基](1→2)-Β-D-葡萄糖苷	Autophagy	Autophagy
	Pennogenin 3-O-beta-chacotrioside 是从七叶一枝花中分离得到的一种天然产物，具有抗结肠癌活性。它可以调节自噬，增加自噬相关蛋白 LC3 和 Beclin-1 的表达。
T3865	beta-Eudesmol β-桉叶醇,Beta-Selinenol,beta-桉叶醇	TRP/TRPV Channel; AChR	Membrane transporter/Ion channel; Neuroscience
	beta-Eudesmol (Beta-Selinenol) 是天然的含氧倍半萜烯，可激活hTRPA1，EC50值为 32.5 μM。Beta-Eudesmol 有增加食欲的功效。
TN1182	11-Keto-beta-boswellic acid 11-Keto-beta-boswellic acid,11-酮基-BETA-乳香酸	Leukotriene Receptor; NF-κB; Lipoxygenase	GPCR/G Protein; Metabolism; NF-κB
	11-Keto-beta-boswellic acid 是来自乳香的一种五环三萜酸，具有抗炎活性和剂量依赖性心脏保护作用，主要是由于抑制5-脂氧合酶、白三烯、NF-κB 的激活和肿瘤坏死因子 α 的产生。
TN3500	beta-Amyrone β-Amyron,β-香树脂酮	COX; AChR; PPAR; Antifection	DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience
	beta-Amyrone (β-Amyron) 对基孔肯雅病毒复制具有抗真菌活性，EC50 为 86 uM。 beta-Amyrone 通过抑制 COX-2 的表达而具有抗炎活性。 beta-Amyrone 表现出抗α-葡萄糖苷酶抑制活性和中等 AChE 活性。 β-Amyrone 可用于炎症、感染和肥胖等疾病的研究。
TN1438	beta-Amyrin acetate beta-香树脂醇乙酸酯	Antioxidant; HMG-CoA Reductase; Epoxide Hydrolase; Antifungal	Metabolism; Microbiology/Virology; oxidation-reduction
	beta-Amyrin acetate 抑制 HMG-CoA 还原酶 (HMGCR) 和 sEH 活性，IC50 为 3.4 μM。 beta-Amyrin acetate 具有抗炎、抗真菌、抗氧化和抗高血脂活性。
T2S2018	7beta-Hydroxylathyrol 7β-Hydroxylathyrol,7-Hydroxylathyrol,7-beta-Hydroxylathyrol,7-羟基千金子二萜醇	P-gp	Membrane transporter/Ion channel; Neuroscience
	7β-Hydroxylathyrol 是天然萜类化合物的一种。
TC0027	beta-Sitosterol acetate	Others	Others
	beta-Sitosterol acetate 是几种被称为植物甾醇的植物性物质之一。
T1373	AC-Beta-ALA-OH	Amino Acids and Derivatives	Metabolism
	AC-Beta-ALA-OH 是单 N-保护氨基酸 (MPAA) 配体，也是异常氨基酸代谢物。
TN1441	Beta-Tocopherol β-生育酚,BETA-生育酚	ERK; MAPK	MAPK
	Beta-Tocopherol 对由 phorbol 12-myristate 13-acetate (PMA) 诱导的人红白血病细胞 (HEL) 粘附有影响。
T3S2152	23-Hydroxybetulinic acid Anemosapogenin,23-羟基白桦酸	Others	Others
	23-Hydroxybetulinic acid (Anemosapogenin) 是一种具有抗癌作用的生物化合物。
T4S2128	Bilobetin 白果双黄酮,白果素	PKA; PPAR	DNA Damage/DNA Repair; Metabolism; Tyrosine Kinase/Adaptors
	Bilobetin 是银杏的活性成分，可改善胰岛素抵抗，增加肝脏对脂质的吸收和氧化，降低极低密度脂蛋白甘油三酯分泌和血液甘油三酯水平，增强组织中 β-氧化的酶的表达和活性，并减弱甘油三酯及其代谢产物的积累。它还增加了 PPARα的磷酸化，核转位和活性，并伴随着 cAMP 水平和 PKA 活性的升高。
T4S1962	beta-Asarone β-细辛脑,(Z)-1,2,4-三甲氧基-5-丙烯基苯;顺式细辛脑,Cis-Isoasarone,Cis-Asarone,Cis-Isoelemicin	NF-κB; JNK	MAPK; NF-κB
	beta-Asarone (Cis-Isoelemicin) 是一种石菖蒲中的主要成分，具有免疫抑制、促进安定、中枢神经系统抑制、降温等功能。它可透过血脑屏障，能够预防帕金森病。
T3S2156	Chrysin 7-O-beta-gentiobioside Chrysin 7-O-β-gentiobioside,白杨素-7-O-龙胆二糖	Others	Others
	Chrysin 7-O-beta-gentiobioside (Chrysin 7-O-β-gentiobioside) 是 Chrysin 的糖基化产物，来自 Spartium junceum。
T5979	1-beta-D-Arabinofuranosyluracil 阿糖尿苷,1-β-D-阿糖尿苷,Uracil 1-β-D-arabinofuranoside	Others	Others
	1-beta-D-Arabinofuranosyluracil (Uracil 1-β-D-arabinofuranoside) 是一种甲氧基腺苷衍生物，从加勒比海绵 Tectitethya crypta 中分离得到。已经证明其具有多种生物活性，如抗炎活性，缓解疼痛和血管舒张特性。它能够抑制小鼠淋巴瘤细胞的增殖。
TN2539	1beta-Hydroxyalantolactone	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	1beta-Hydroxyalantolactone 是从药用植物大英花的花头中分离出的小分子化合物，可抑制细胞中TNF-α、IL-17、IFN-γ的表达，促进TNF-α、IFN-γ、IL-17的分泌，可防治类风湿性关节炎。
T8335	Lycobetaine acetate 氧化石蒜碱乙酸盐,Oxylycorine	Others	Others
	Lycobetaine acetate (Oxylycorine) 是一种潜在的抗罗克福提青霉和黑曲霉的生物杀菌剂。
T5S2350	Beta-Acetoxyisovalerylshikonin 乙酰氧基异戊酰阿卡宁,Acetoxyisovalerylalkannin,β-乙酰氧基异戊酰阿卡宁	Others	Others
	Acetoxyisovalerylshikonin 是一种萘醌衍生物，提取自Arnebia euchroma 中。
T2S0765	Epibetulinic acid	NO Synthase; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Epibetulinic acid 对细菌内毒素刺激的小鼠巨噬细胞 (RAW 264.7) 中 NO 和前列腺素 E(2) 的产生具有有效的抑制作用，IC50分别为 0.7 和 0.6 μM，具有抗炎活性。
TN1166	1,3,6-Tri-O-galloyl-beta-D-glucose 1,3,6-三没食子酰葡萄糖,1,3,6-Tri-O-galloyl-β-D-glucose,1,3,6-Tri-O-galloylglucose,1,3,6-三-O-3,4,5-三羟基苯甲酰-BETA-D-葡萄糖	Immunology/Inflammation related	Immunology/Inflammation
	1,3,6-Tri-O-galloyl-beta-D-glucose (1,3,6-Tri-O-galloylglucose) 是一种酚类化合物，分离自Black Walnut Kernels 中。
T3796	Betulinaldehyde Betulinic aldehyde,Betulinal,Betunal,白桦脂醛	Apoptosis; Antibacterial	Apoptosis; Microbiology/Virology
	Betulinaldehyde (Betunal) 是五环三萜，有抗金黄色葡萄球菌等细菌和真菌作用。
TN2627	14beta-Benzoyloxy-2-deacetylbaccatin VI	Others	Others
	14beta-Benzoyloxy-2-deacetylbaccatin VI是一种天然产物，属于红豆杉科红豆杉属，其产品编号为 TN2627，CAS号为 705973-69-9。14beta-Benzoyloxy-2-deacetylbaccatin VI可用作对照参考。
TN2867	3,4,5-Trimethoxyphenyl-(6-O-galloyl)-O-beta-D-glucopyranoside	Antifection	Microbiology/Virology
	3,4,5-Trimethoxyphenyl-(6'-O-galloyl)-O-beta-D-glucopyranoside shows in vitro antiplasmodial activity.
TN1442	Betulinic acid methyl ester	Antifection	Microbiology/Virology
	Betulinic acid methyl ester showed antiplasmodial activity against chloroquine-resistant Plasmodium falciparum parasites in vitro.It also inhibited B16 2F2 cell proliferation by induction of apoptosis.
TN2972	3-O-(E)-p-Coumaroylbetulin	Others	Others
	3-β-O-trans-p-coumaroylbetulinol has anti-angiogenic effect, it possesses significant anti-proliferative activity with 66.7% inhibition at 100uM.
TN3509	Betulin caffeate	Others	Others
	Betulin-3β-caffeate shows moderate antioxidant activity with IC50 value 108.0 ug/ml.
TN3503	Beta-Furoyleupatolide	Others	Others
	Beta-Furoyleupatolide 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3503，CAS号为 114437-24-0。
TN6472	Columbianetin beta-D-glucopyranoside
	Columbianetin-beta-D-glucopyranoside exhibits anti-inflammatory and analgesic properties, it also shows strong inhibiting activity against platelet aggregation.
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天然产物

11-Beta-hydroxyandrostenedione

Cat.No: T14001

Synonym: 4-雄烯-11β-醇-3,17-二酮,NSC-17102,4-Androsten-11β-ol-3,17-dione

Target: Endogenous Metabolite

Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside

Cat.No: TN6600

Target: HIV Protease

6'-O-beta-D-Glucosylgentiopicroside

Cat.No: T4S1439

Synonym: 6'-O-β-D-葡萄糖基龙胆苦苷,6'-O-Glucosylgentiopicroside

Target: Antifungal

3-O-beta-D-Glucopyranosylplatycodigenin

Cat.No: TN1260

Target: Others

Cat.No: T2S1792

Synonym: 石蒜内胺,Ungeremine,石蒜醋胺,石蒜碱内铵盐

Target: Antibacterial

3-Acetyl-beta-boswellic acid

Cat.No: TN1258

Synonym: 3-O-Acetyl-beta-boswellic acid,3-乙酰基-BETA-乳香酸

Target: DNA/RNA Synthesis

Betulonic acid

Cat.No: T5S0018

Synonym: 路路通酸,(+)-Betulonic acid,Betunolic acid,Liquidambaric acid

Target: Parasite, HSV

Beta-mangostin

Cat.No: TN1019

Synonym: β-Mangostin,beta-倒捻子素

Target: Apoptosis, Antibacterial, Parasite

Betaine chloride

Cat.No: T0019

Synonym: Betaine hydrochloride,盐酸甜菜碱

Target: Others, Chloride channel, Endogenous Metabolite

Betulinic acid

Cat.No: T2830

Synonym: 白桦脂酸,桦木酸,ALS-357,Lupatic acid,Betulic acid

Target: Apoptosis, Mitophagy, NF-κB, HIV Protease, Topoisomerase, Endogenous Metabolite, Aminopeptidase, Autophagy

Cat.No: T3825

Synonym: Praeruptorin D,党参炔苷

Target: Others

Cat.No: T3121

Synonym: Trochol,betulinic alcohol,betuline,betulinol,桦木醇,Betulol,白桦脂醇

Target: Apoptosis, Endogenous Metabolite, Lipid, Fatty Acid Synthase

Cat.No: T8846

Synonym: B-escin,AESCINE,beta-七叶素

Target: Immunology/Inflammation related

3-O-Acetyl-11-hydroxy-beta-boswellic acid

Cat.No: TN1255

Target: Lipoxygenase

Tauro-Obeticholic acid

Cat.No: T13092

Target: FXR

Beta-Sitosterol

Cat.No: T2966

Synonym: Cupreol,谷甾醇,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,beta-谷甾醇,22,23-Dihydrostigmasterol,Betaprost

Target: Apoptosis, Lipase, Endogenous Metabolite

(S)-(-)-beta-Citronellol

Cat.No: TN4931

Target: Others

Luteolin-3-O-beta-D-glucuronide

Cat.No: TQ0070

Target: Others

Acacetin-7-O-beta-D-galactopyranoside

Cat.No: TN7212

Target: Others

Nortrachelogenin-8'-O-beta-glucoside

Cat.No: TN4674

Target: Others

Hederagenin 28-O-beta-D-glucopyranosyl ester

Cat.No: T3S0208

Synonym: Hederagenin-28-beta-D-glucopyranoside,常春苷元-28-BETA-D-吡喃葡萄糖苷,常春藤皂苷元28-O-beta-D-吡喃葡萄糖酯

Target: Others

2"-O-beta-L-galactopyranosylorientin

Cat.No: T5713

Synonym: 荭草素-2"-0-B-L半乳糖苷,荭草素-2"-O-BETA-L-半乳糖苷,2''-O-β-L-Galorientin

Target: Others

Cat.No: T3243

Synonym: Abromine,glycine betaine,oxyneurine,trimethylglycine,lycine,甜菜碱

Target: Others, Endogenous Metabolite

Pennogenin 3-O-beta-chacotrioside

Cat.No: T8166

Synonym: 偏诺皂苷元-3-O-Α-L-吡喃鼠李糖-(1→4)[Α-L-吡喃鼠李糖基](1→2)-Β-D-葡萄糖苷

Target: Autophagy

beta-Eudesmol

Cat.No: T3865

Synonym: β-桉叶醇,Beta-Selinenol,beta-桉叶醇

Target: TRP/TRPV Channel, AChR

11-Keto-beta-boswellic acid

Cat.No: TN1182

Synonym: 11-Keto-beta-boswellic acid,11-酮基-BETA-乳香酸

Target: Leukotriene Receptor, NF-κB, Lipoxygenase

Cat.No: TN3500

Synonym: β-Amyron,β-香树脂酮

Target: COX, AChR, PPAR, Antifection

beta-Amyrin acetate

Cat.No: TN1438

Synonym: beta-香树脂醇乙酸酯

Target: Antioxidant, HMG-CoA Reductase, Epoxide Hydrolase, Antifungal

7beta-Hydroxylathyrol

Cat.No: T2S2018

Synonym: 7β-Hydroxylathyrol,7-Hydroxylathyrol,7-beta-Hydroxylathyrol,7-羟基千金子二萜醇

Target: P-gp

beta-Sitosterol acetate

Cat.No: TC0027

Target: Others

AC-Beta-ALA-OH

Cat.No: T1373

Target: Amino Acids and Derivatives

Beta-Tocopherol

Cat.No: TN1441

Synonym: β-生育酚,BETA-生育酚

Target: ERK, MAPK

23-Hydroxybetulinic acid

Cat.No: T3S2152

Synonym: Anemosapogenin,23-羟基白桦酸

Target: Others

Cat.No: T4S2128

Synonym: 白果双黄酮,白果素

Target: PKA, PPAR

Cat.No: T4S1962

Synonym: β-细辛脑,(Z)-1,2,4-三甲氧基-5-丙烯基苯;顺式细辛脑,Cis-Isoasarone,Cis-Asarone,Cis-Isoelemicin

Target: NF-κB, JNK

Chrysin 7-O-beta-gentiobioside

Cat.No: T3S2156

Synonym: Chrysin 7-O-β-gentiobioside,白杨素-7-O-龙胆二糖

Target: Others

1-beta-D-Arabinofuranosyluracil

Cat.No: T5979

Synonym: 阿糖尿苷,1-β-D-阿糖尿苷,Uracil 1-β-D-arabinofuranoside

Target: Others

1beta-Hydroxyalantolactone

Cat.No: TN2539

Target: IL Receptor, TNF

Lycobetaine acetate

Cat.No: T8335

Synonym: 氧化石蒜碱乙酸盐,Oxylycorine

Target: Others

Beta-Acetoxyisovalerylshikonin

Cat.No: T5S2350

Synonym: 乙酰氧基异戊酰阿卡宁,Acetoxyisovalerylalkannin,β-乙酰氧基异戊酰阿卡宁

Target: Others

Epibetulinic acid

Cat.No: T2S0765

Target: NO Synthase, Prostaglandin Receptor

1,3,6-Tri-O-galloyl-beta-D-glucose

Cat.No: TN1166

Synonym: 1,3,6-三没食子酰葡萄糖,1,3,6-Tri-O-galloyl-β-D-glucose,1,3,6-Tri-O-galloylglucose,1,3,6-三-O-3,4,5-三羟基苯甲酰-BETA-D-葡萄糖

Target: Immunology/Inflammation related

Betulinaldehyde

Cat.No: T3796

Synonym: Betulinic aldehyde,Betulinal,Betunal,白桦脂醛

Target: Apoptosis, Antibacterial

14beta-Benzoyloxy-2-deacetylbaccatin VI

Cat.No: TN2627

Target: Others

3,4,5-Trimethoxyphenyl-(6-O-galloyl)-O-beta-D-glucopyranoside

Cat.No: TN2867

Target: Antifection

Betulinic acid methyl ester

Cat.No: TN1442

Target: Antifection

3-O-(E)-p-Coumaroylbetulin

Cat.No: TN2972

Target: Others

Betulin caffeate

Cat.No: TN3509

Target: Others

Beta-Furoyleupatolide

Cat.No: TN3503

Target: Others

Columbianetin beta-D-glucopyranoside

Cat.No: TN6472

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