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Search Results for " ida "

487

抑制剂 & 化合物

47

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T65733	Fmoc-Ida-OH
	Fmoc-Ida-OH 是一种氨基酸衍生物，在生命科学相关研究中具有广泛的应用。
T8132	Iron sucrose Iron saccharate,蔗糖铁,Sucroferric oxyhydroxide	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Iron sucrose (Sucroferric oxyhydroxide) 是一种静脉注射铁制剂，也是一种促氧化剂，可用于研究缺铁性贫血。
T8555	Neuraminidase-IN-1 Novel NA Inhibitor,Compound Y-1	Others; Influenza Virus	Microbiology/Virology; Others
	Neuraminidase-IN-1 (Compound Y-1) 是一种神经氨酸酶抑制剂，其IC50值为 0.21 μM，具有抗H1N1流感病毒的活性。
T13215	N-(3-Chloro-4-morpholinophenyl)-N'-hydroxyformimidamide N-(3-氯-4-吗啉代苯基)-N'-羟基甲脒,TS-011	Others	Others
	N-(3-Chloro-4-morpholinophenyl)-N'-hydroxyformimidamide (TS-011) 是一种选择性 20-羟基二十碳四烯酸合成抑制剂。
Fr16629	4-(Imidazol-1-yl)phenol
	4-(Imidazol-1-yl)phenol 是一种高效信号增强剂，用于辣根过氧化物酶（HRP）-鲁米诺化学发光（CL）免疫测定。
T9494	Imidazole-5-propionic acid Imidazolylpropionic acid,3-(咪唑-4-基)丙酸,SALOR-INT L480258-1EA,Deamino-histidine	Dehydrogenase	Metabolism
	Imidazole-5-propionic acid (Imidazolylpropionic acid) 是组氨酸代谢的产物，可能涉及氧化或转氨作用。它是 G. candidum 组氨醇脱氢酶的有效抑制剂，IC50 值低至 3.17 microM。
T5317	Cridanimod CMA,吖啶酮乙酸,XBIO-101,10-carboxymethyl-9-acridanone	Progesterone Receptor; STING; IFNAR	Immunology/Inflammation; Others
	Cridanimod (10-carboxymethyl-9-acridanone, CMA) 是一种是小分子免疫调节剂和干扰素诱导剂，是一种孕酮受体激活剂，能够诱导 IFNα和IFNβ的表达，显著增加 PR 的表达。
T61278	Aminopeptidase-IN-1	Aminopeptidase	Metabolism
	Aminopeptidase-IN-1 是一种有效的胰岛素调节氨肽酶 (IRAP) 抑制剂（Ki： 7.7 μM）。Aminopeptidase-IN-1 可用于认知和记忆障碍的研究。
T6018	Zosuquidar trihydrochloride 唑喹达三盐酸盐,Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride	P-gp	Membrane transporter/Ion channel; Neuroscience
	Zosuquidar trihydrochloride (LY-335979 trihydrochloride) 是一种P-糖蛋白抑制剂，Ki 值为 59 nM。
T26081	Ridazolol Ridazololum
	Ridazolol is a vasodilating and cardioselective beta adrenergic blocker.
T0239	Lonidamine AF1890,氯尼达明,DICA,Diclondazolic Acid	Apoptosis; Hexokinase; Mitochondrial Metabolism	Apoptosis; Metabolism
	Lonidamine (Diclondazolic Acid) 是一种抗肿瘤药物，是己糖激酶、线粒体丙酮酸载体和质膜单羧酸转运蛋白抑制剂，同时也抑制线粒体复合物 II。
T6542	Imidapril hydrochloride Novaloc,Imidapril HCl,盐酸咪达普利,Tanapril,TA-6366	RAAS	Endocrinology/Hormones
	Imidapril hydrochloride (Tanapril) 是一种血管紧张素转换酶 (ACE) 抑制剂，具有抗高血压活性。
T17036	Tenidap CP-66248	COX	Immunology/Inflammation; Neuroscience
	Tenidap is a non-steroidal anti-inflammatory drug and is a selective COX-1 inhibitor (IC50: 0.03 µM and 1.2 µM for COX-1 and COX-2, respectively). Tenidap is also a specific SLC26A3 inhibitor.
T67728	α-Glucosidase-IN-23	Glucosidase	Metabolism
	α-Glucosidase-IN-23 是具有口服活性的 α-Glucosidase 抑制剂。α-Glucosidase-IN-23 通过抑制 a-glucosidase 降低血糖 (IC50= 4.48 μM)。α-Glucosidase-IN-23 可用于糖尿病的研究。
T9837	N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bromoaniline	ALK	Angiogenesis; Tyrosine Kinase/Adaptors
	N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bromoaniline 是一种有效的 ALK5 抑制剂，IC50 为 7nM。
T9553	8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxylic acid	Others	Others
	8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-car 是一种 H+/K+ ATPase 抑制剂，IC50=0.38μM。
T10509	Xanthine oxidase-IN-1 4-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid	Xanthine Oxidase	Metabolism
	Xanthine oxidase-IN-1是一种有效的黄嘌呤氧化酶抑制剂(IC50值:6.5 nM),是一种利用核酸和核苷酸介质降解产生的生物活性核苷酸在嘌呤分解代谢中起核心作用的化合物，
T20535	Carnidazole ME 108,NSC293873,NSC 293873,ME-108,NSC-293873,ME108	Antibiotic; Parasite	Microbiology/Virology
	Carnidazole (ME-108) 具有抗原生动物活性，可用于治疗滴虫感染的研究。
T60186	(S)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-2-(pyrimidin-5-yl)-1,2,3,4-tetrahydroisoquinoline-7-carboxamide	Discoidin Domain Receptor (DDR)	Tyrosine Kinase/Adaptors
	MitoBloCK-6 是一种有效的 Erv1/ALR 抑制剂，IC50 分别为 900 nM 和 700 nM。MitoBloCK-6 还抑制 Erv2 (IC50=1.4 μM)。MitoBloCK-6 可通过细胞色素 c 的释放诱导 hESCs 细胞凋亡。
T77512	1H-Benzimidazole-6-carboxamide, N-[3-(aminocarbonyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-	Others	Others
	1H-Benzimidazole-6-carboxamide, N-[3-(aminocarbonyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-可能具有抗肿瘤活性。
T78984	Xanthine oxidase-IN-10 XO8 analog	ROS	Immunology/Inflammation
	Xanthine oxidase-IN-10 (XO8 analog) 是一种黄嘌呤氧化酶 (XO) 抑制剂，可用于研究痛风。
T77643	2-(Chloromethyl)Imidazo[1,2-A]Pyridine	Others	Others
	2-(Chloromethyl)imidazo[1,2-a]pyridine 具有潜在的抗虫活性，可用于合成有活性的化合物。
T6974	Saccharin 1-methylimidazole 糖精-1-甲基咪唑盐,SMI,Saccharin 1-methylimidazole (SMI)	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Saccharin 1-methylimidazole (SMI) 是一种用于 DNA 和 RNA 合成的通用激活剂。
Fr13736	4-Phenylimidazole 5-Phenyl-1H-imidazole
	Compound Fr13736 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 Fr13736，CAS号为 670-95-1。
T37885	1-Dodecylimidazole	Antifungal	Microbiology/Virology
	1-Dodecylimidazole 是溶酶体活性洗涤剂。1-Dodecylimidazole 通过在溶酶体中的酸依赖性积累、溶酶体膜的破坏和半胱氨酸蛋白酶释放到细胞质中而导致细胞死亡。它显示出降胆固醇和广谱抗真菌活性。
T8426	Encequidar HM30181,HM30181A	P-gp	Membrane transporter/Ion channel; Neuroscience
	Encequidar (HM30181A) 是一种选择性 P-糖蛋白抑制剂。
T10678	Carboxypeptidase G2 (CPG2) Inhibitor CPG2 Inhibitor,Carboxypeptidase G2 Inhibitor	Carboxypeptidase	Proteases/Proteasome
	Carboxypeptidase G2 (CPG2) Inhibitor (CPG2 Inhibitor) 是新型的羧肽酶 G2(CPG2)抑制剂，显示出抗癌活性。
T21899	Misonidazole SR-1354,SR1354,Ro 7-0582	GPX	oxidation-reduction
	Misonidazole 是一种缺氧肿瘤细胞放射增敏剂，具有抗菌活性。
T72077	Imidacloprid-urea
	Imidacloprid-urea 是吡虫啉的次级代谢产物。吡虫啉是一种有效且广泛使用的新烟碱类化合物，对谷物，蔬菜，茶叶和棉花的害虫具有抑制作用。Imidacloprid-urea 可以占据或阻断吡虫啉在土壤上的吸附位点，从而可能影响吡虫啉在环境中的去向、转运和生物利用度。
T5884	Chelidamic acid 4-氧代-1,4-二氢-2,6-吡啶二甲酸,白屈氨酸	GluR	Neuroscience
	Chelidamic acid 是一种有效的谷氨酸脱羧酶抑制剂(Ki:33 μM)，也是含有吡喃骨架的杂环有机酸，与金属离子有良好的配位能力。
T0844	Sulfamethoxypyridazine CL 13494,磺胺甲氧哒嗪	Antibacterial; Antibiotic; PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation; Microbiology/Virology
	Sulfamethoxypyridazine (CL 13494) 是一种用于研究疱疹性皮炎的长效磺胺类药物。
T6969	Imidacloprid	Others	Others
	Imidacloprid 是一种新烟碱类农药，广泛用于控制蔬菜，谷物，茶叶和棉花的害虫。
T76148	Glucose oxidase	Endogenous Metabolite	Metabolism
	Glucose oxidase 是从真菌黑曲霉中提取的酶，是食品工业中一种重要的工业用酶，广泛用于葡萄酒、啤酒、果汁、奶粉等食品脱氧、面粉改良、防止食品褐变等方面。Glucose oxidase 具有抗氧化和潜在的抗癌活性。
T11284	FIDAS-3	Others; Wnt/beta-catenin; Methionine Adenosyltransferase (MAT)	Chromatin/Epigenetic; Cytoskeletal Signaling; Others; Stem Cells
	FIDAS-3 是一种强效Wnt 抑制剂，也是一种二苯乙烯衍生物，对甲硫氨酸腺苷转移酶 2A (MAT2A) 的IC50为 4.9 μM。它能够与 S-腺苷甲硫氨酸有效竞争MAT2A 结合，并具有抗癌作用。
T60715	α-Glucosidase-IN-4	Glucosidase	Metabolism
	α-Glucosidase-IN-4 是一种有效的α- 葡萄糖苷酶 (α-glucosidase)抑制剂，具有降血压和降糖活性。
T9315	2H-Imidazo[4,5-b]pyrazin-2-one, 1,3-dihydro-6-[6-(1-hydroxy-1-methylethyl)-3-pyridinyl]-1-[(tetrahydro-2H-pyran-4-yl)methyl]-	Others	Others
	2H-Imidazo[4,5-b]pyrazin-2-one, 1,3-dihydro-6-[6-(1-hydroxy-1-methylethyl)-3-pyridinyl]-1-[(tetrahydro-2H-pyran-4-yl)methyl]- 是有效的mTOR 抑制剂，对于mTOR 和PI3Kα的IC50分别为0.176 μM 和 >30 μM。
T3486	3-MATIDA	GluR; NMDAR	Neuroscience
	3-MATIDA 是一种有效的 mGluR-1 拮抗剂（IC50：6.3 μM，大鼠 mGluR-1a）。显示出 ≥ 40 倍于其他受体的选择性：mGluR-5、mGluR-2、mGluR-4 (mGluR-4a) (IC50 > 300 μM)、NMDA 和 GluR (AMPA) (IC50 = 250 μM)。 3-MATIDA 在体外培养的鼠皮质细胞和大鼠海马切片培养物中充当神经保护剂。
T0638	2-Methyl-4-nitroimidazole	Others	Others
	2-Methyl-4-nitroimidazole（2-MNI）是一种杂环化合物，具有抗菌、抗炎和抗肿瘤活性。2-MNI 已被用于多种领域，包括生物化学、药理学和生物技术。
T67914	Insecticidal agent 364	mTOR; Autophagy	Autophagy; PI3K/Akt/mTOR signaling
	Insecticidal agent 364是一种雷帕霉素激酶靶蛋白的选择性小分子抑制剂。Insecticidal agent 364具有抗肿瘤活性，通过抑制mTOR, Insecticidal agent 364旨在破坏参与癌细胞生长和存活的信号通路，从而潜在地抑制肿瘤生长。
T9345	Aminopeptidase M	Others	Others
	Aminopeptidase M 抑制对多种疾病（例如高度血管化的癌症类型）具有重要意义。
T1722	5-Amino-4-imidazolecarboxamide	Others	Others
	5-Amino-4-imidazolecarboxamide 是一种咪唑衍生物。
T8612	1-Methyl-2-(Methylthio)iMidazole	Others	Others
	1-Methyl-2-(Methylthio)iMidazole 是 Methimazole 的杂质，Methimazole 是一种硫脲类抗甲状腺药物。
T3086	Mesoridazine Besylate Mesoridazine benzenesulfonate,Serentil,苯磺酸美索达嗪	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Mesoridazine Besylate (Serentil) 是一种哌啶类精神安定药，属于称为吩噻嗪类的药物，用于治疗精神分裂症。它是硫利达嗪的代谢物。
T64133L	Laniquidar TFA Laniquidar TFA(197509-46-9 Free base),R101933	P-gp	Membrane transporter/Ion channel; Neuroscience
	Laniquidar TFA (R101933) 是一种新型口服非竞争性P-糖蛋白(P-gp)抑制剂，IC50 值为 0.51 μM。Laniquidar的生物利用度有限，可用于调节多药耐药性转运体。Laniquidar可用于研究急性髓性白血病(AML)和骨髓增生异常综合征(MDS)。
T10667	Calmidazolium chloride R 24571,钙调蛋白抑制剂	CaMK; Autophagy	Autophagy; Neuroscience
	Calmidazolium chloride (R 24571) 是一种钙调蛋白拮抗剂，对CaM 依赖性磷酸二酯酶和钙调蛋白诱导的红细胞Ca2+转运ATP 酶活化有拮抗作用，IC50分别为0.15和0.35 μM。Calmidazolium chloride 结合CaMK 的Kd 值为3 nM。Calmidazolium chloride 在抗癌领域有研究的价值。
T0115	Idazoxan hydrochloride RX 781094,盐酸咪唑克生	Adrenergic Receptor; Imidazoline Receptor	GPCR/G Protein; Neuroscience
	Idazoxan hydrochloride (RX 781094) 是一种 α2-肾上腺素受体拮抗剂，改善帕金森氏病、L-DOPA 引起的运动障碍和实验性帕金森病的运动症状。它也是咪唑啉受体拮抗剂，可竞争性拮抗唑啉样药物的中枢性降压作用。
T6010	Idarubicin hydrochloride 盐酸伊达比星,Idamycin,4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl,4-Demethoxydaunorubicin hydrochloride,Idarubicin HCl,伊达比星盐酸盐,Zavedos	Topoisomerase; Antibacterial; Autophagy; Antifungal	Autophagy; DNA Damage/DNA Repair; Microbiology/Virology
	Idarubicin hydrochloride (Zavedos) 是一种蒽环类抗白血病药物，能抑制细菌和酵母菌生长，还抑制拓扑异构酶 II，干扰 DNA 复制和 RNA 转录。
T0195	Secnidazole RP-14539,PM-185184,塞克硝唑	Antibiotic; Parasite	Microbiology/Virology
	Secnidazole (PM-185184) 是一种具有口服活性唑类抗生素，半衰期比甲硝唑更长。它有潜力研究细菌性阴道病。
T2112	Fexinidazole 非昔硝唑,HOE 239	Others; Parasite	Microbiology/Virology; Others
	Fexinidazole (HOE 239) 是具有口服活性的硝基咪唑抗锥虫药物。它显示出对布鲁氏杆菌亚种和菌株的杀锥虫活性，IC50值为 0.7-3.3 μM (0.2-0.9 μg/ml)。它具有用于因感染布鲁氏菌引起的人类昏睡病的潜力。
T77385	Idactamab INT-001
	Idactamab (INT-001) 是一种人氨基酸转运蛋白 ASCT2 的单克隆抗体。

化合物

Cat.No: T65733

Cat.No: T8132

Synonym: Iron saccharate,蔗糖铁,Sucroferric oxyhydroxide

Target: Reactive Oxygen Species

Neuraminidase-IN-1

Cat.No: T8555

Synonym: Novel NA Inhibitor,Compound Y-1

Target: Others, Influenza Virus

N-(3-Chloro-4-morpholinophenyl)-N'-hydroxyformimidamide

Cat.No: T13215

Synonym: N-(3-氯-4-吗啉代苯基)-N'-羟基甲脒,TS-011

Target: Others

4-(Imidazol-1-yl)phenol

Cat.No: Fr16629

Imidazole-5-propionic acid

Cat.No: T9494

Synonym: Imidazolylpropionic acid,3-(咪唑-4-基)丙酸,SALOR-INT L480258-1EA,Deamino-histidine

Target: Dehydrogenase

Cat.No: T5317

Synonym: CMA,吖啶酮乙酸,XBIO-101,10-carboxymethyl-9-acridanone

Target: Progesterone Receptor, STING, IFNAR

Aminopeptidase-IN-1

Cat.No: T61278

Target: Aminopeptidase

Zosuquidar trihydrochloride

Cat.No: T6018

Synonym: 唑喹达三盐酸盐,Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride

Target: P-gp

Cat.No: T26081

Synonym: Ridazololum

Cat.No: T0239

Synonym: AF1890,氯尼达明,DICA,Diclondazolic Acid

Target: Apoptosis, Hexokinase, Mitochondrial Metabolism

Imidapril hydrochloride

Cat.No: T6542

Synonym: Novaloc,Imidapril HCl,盐酸咪达普利,Tanapril,TA-6366

Target: RAAS

Cat.No: T17036

Synonym: CP-66248

Target: COX

α-Glucosidase-IN-23

Cat.No: T67728

Target: Glucosidase

N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bromoaniline

Cat.No: T9837

Target: ALK

8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxylic acid

Cat.No: T9553

Target: Others

Xanthine oxidase-IN-1

Cat.No: T10509

Synonym: 4-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid

Target: Xanthine Oxidase

Cat.No: T20535

Synonym: ME 108,NSC293873,NSC 293873,ME-108,NSC-293873,ME108

Target: Antibiotic, Parasite

(S)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-2-(pyrimidin-5-yl)-1,2,3,4-tetrahydroisoquinoline-7-carboxamide

Cat.No: T60186

Target: Discoidin Domain Receptor (DDR)

1H-Benzimidazole-6-carboxamide, N-[3-(aminocarbonyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-

Cat.No: T77512

Target: Others

Xanthine oxidase-IN-10

Cat.No: T78984

Synonym: XO8 analog

Target: ROS

2-(Chloromethyl)Imidazo[1,2-A]Pyridine

Cat.No: T77643

Target: Others

Saccharin 1-methylimidazole

Cat.No: T6974

Synonym: 糖精-1-甲基咪唑盐,SMI,Saccharin 1-methylimidazole (SMI)

Target: DNA/RNA Synthesis

4-Phenylimidazole

Cat.No: Fr13736

Synonym: 5-Phenyl-1H-imidazole

1-Dodecylimidazole

Cat.No: T37885

Target: Antifungal

Cat.No: T8426

Synonym: HM30181,HM30181A

Target: P-gp

Carboxypeptidase G2 (CPG2) Inhibitor

Cat.No: T10678

Synonym: CPG2 Inhibitor,Carboxypeptidase G2 Inhibitor

Target: Carboxypeptidase

Cat.No: T21899

Synonym: SR-1354,SR1354,Ro 7-0582

Target: GPX

Imidacloprid-urea

Cat.No: T72077

Chelidamic acid

Cat.No: T5884

Synonym: 4-氧代-1,4-二氢-2,6-吡啶二甲酸,白屈氨酸

Target: GluR

Sulfamethoxypyridazine

Cat.No: T0844

Synonym: CL 13494,磺胺甲氧哒嗪

Target: Antibacterial, Antibiotic, PD-1/PD-L1

Cat.No: T6969

Target: Others

Glucose oxidase

Cat.No: T76148

Target: Endogenous Metabolite

Cat.No: T11284

Target: Others, Wnt/beta-catenin, Methionine Adenosyltransferase (MAT)

α-Glucosidase-IN-4

Cat.No: T60715

Target: Glucosidase

2H-Imidazo[4,5-b]pyrazin-2-one, 1,3-dihydro-6-[6-(1-hydroxy-1-methylethyl)-3-pyridinyl]-1-[(tetrahydro-2H-pyran-4-yl)methyl]-

Cat.No: T9315

Target: Others

Cat.No: T3486

Target: GluR, NMDAR

2-Methyl-4-nitroimidazole

Cat.No: T0638

Target: Others

Insecticidal agent 364

Cat.No: T67914

Target: mTOR, Autophagy

Aminopeptidase M

Cat.No: T9345

Target: Others

5-Amino-4-imidazolecarboxamide

Cat.No: T1722

Target: Others

1-Methyl-2-(Methylthio)iMidazole

Cat.No: T8612

Target: Others

Mesoridazine Besylate

Cat.No: T3086

Synonym: Mesoridazine benzenesulfonate,Serentil,苯磺酸美索达嗪

Target: Dopamine Receptor, 5-HT Receptor

Cat.No: T64133L

Synonym: Laniquidar TFA(197509-46-9 Free base),R101933

Target: P-gp

Calmidazolium chloride

Cat.No: T10667

Synonym: R 24571,钙调蛋白抑制剂

Target: CaMK, Autophagy

Idazoxan hydrochloride

Cat.No: T0115

Synonym: RX 781094,盐酸咪唑克生

Target: Adrenergic Receptor, Imidazoline Receptor

Idarubicin hydrochloride

Cat.No: T6010

Synonym: 盐酸伊达比星,Idamycin,4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl,4-Demethoxydaunorubicin hydrochloride,Idarubicin HCl,伊达比星盐酸盐,Zavedos

Target: Topoisomerase, Antibacterial, Autophagy, Antifungal

Cat.No: T0195

Synonym: RP-14539,PM-185184,塞克硝唑

Target: Antibiotic, Parasite

Cat.No: T2112

Synonym: 非昔硝唑,HOE 239

Target: Others, Parasite

Cat.No: T77385

Synonym: INT-001

Cat. No.	Product Name	Target	Signaling Pathways
T7544	Fucoidan 岩藻多糖	Others	Others
	Fucoidan 是一种 α-淀粉酶和 α-葡萄糖苷酶的有效抑制剂，是一种生物特性多糖。它具有抗凝血，抗肿瘤，抗氧化和抗脂肪特性。
TN7167	2,4,5-Tribromoimidazole 2,4,5-三溴咪唑,2,4,5-Tribromo-1H-imidazole	Others	Others
	2,4,5-Tribromoimidazole (2,4,5-Tribromo-1H-imidazole) 是一种海洋来源的天然产物，存在于 Hexaplex trunculus。
T1705	5-Amino-3H-imidazole-4-Carboxamide 4-Amino-5-imidazolecarboxamide,AICA,4-氨基-5-咪唑甲酰胺,5-Aminoimidazole-4-carboxamide	Endogenous Metabolite	Metabolism
	5-Amino-3H-imidazole-4-Carboxamide (AICA) 是一种合成嘌呤（尤其是核碱基腺嘌呤和鸟嘌呤）的重要前体。
T19357	Hyaluronidase Hyaluronate 4-glycanohydrolase,Hyaluronoglucosaminidase,透明质酸酶	Others	Others
	Hyaluronidase (Hyaluronate 4-glycanohydrolase) 是一种天然存在的酶，能够分裂糖苷键，使透明质酸解聚。它可用于眼科手术。
TN7149	5-[(1H-indol-3-yl)methylidene]imidazolidine-2,4-dione (4Z)-4-(1H-indol-3-ylmethylidene)-4H-imidazole-2,5-diol,(5Z)-5-(1H-indol-3-ylmethylidene)imidazolidine-2,4-dione	Others	Others
	5-[(1H-indol-3-yl)methylidene]imidazolidine-2,4-dione ((4Z)-4-(1H-indol-3-ylmethylidene)-4H-imidazole-2,5-diol) 是一种海洋来源的天然产物，存在于Leptopsammia pruvoti。
T5202	Imidazole Glyoxaline,1,3-Diaza-2,4-cyclopentadiene,1,3-diazole,咪唑	Others	Others
	Imidazole 是一种高极性化合物，是一种平面五元环，已被广泛用作腐蚀抑制剂。
T1556	Ornidazole Tiberal,Ornidazolum,NSC 95075,Ro 7-0207,奥硝唑	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Ornidazole (Tiberal) 是一种5-硝基咪唑衍生物，能抗原生动物和厌氧菌。
T1506	Vidarabine Adenine Arabinoside,阿糖腺苷,9-β-D-Arabinofuranosyladenine,Vira-A,Arabinosyladenine,Ara-A	Nucleoside Antimetabolite/Analog; Tyrosine Kinases; DNA/RNA Synthesis; Antibiotic; HSV	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Vidarabine (Adenine Arabinoside) 是从链霉菌分离的核苷类抗生素，能抗单纯性疱疹和水痘-带状疱疹病毒。它对 HSV-1 和 HSV-2 的 IC50值分别为 9.3 μg/ml 和 11.3 μg/ml。
T2736	Sodium Demethylcantharidate Sodium norcantharidin,去甲斑蝥酸钠	Others; Endogenous Metabolite	Metabolism; Others
	Sodium Demethylcantharidate (Sodium norcantharidin) 是内源性代谢产物的一种。
T5735	Methyl deacetylasperulosidate Deacetyl asperulosidic acid methyl ester,6α-Hydroxygeniposide,去乙酰车叶草苷酸甲酯	Others	Others
	Methyl deacetylasperulosidate (6α-Hydroxygeniposide) 是环烯醚萜类化合物，能够降低正常小鼠的血糖水平，对小鼠具有通便作用。
T6194	Fidaxomicin 非达米星,Tiacumicin B,OPT-80,Clostomicin B1,PAR-101	Apoptosis; DNA/RNA Synthesis; Antibacterial; Antibiotic	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Fidaxomicin (Tiacumicin B) 是一种大环RNA 聚合酶抑制剂，具有窄谱活性。它选择性地根除致病性艰难梭菌，对构成正常健康肠道菌群的多种细菌影响很小。
T1079	Metronidazole Flagyl,Metronidazol,甲硝唑,Anagiardil	Apoptosis; NADPH; Hydrogenase; Antibacterial; Antibiotic; Parasite; Antifection	Apoptosis; Metabolism; Microbiology/Virology
	Metronidazole (Metronidazol) 是一种合成的硝基咪唑衍生物，具有抗原生动物和抗菌活性。
T7958	Methyl arachidate 花生酸甲酯,Methyl Icosanoate	Others; Aminopeptidase	Metabolism; Others
	Methyl arachidate (Methyl Icosanoate) 是一种天然化合物，具有白三烯 A4 水解酶 (LTA4H) 抑制活性。
T4824	5,6-Dimethyl-1H-benzo[d]imidazole 5,6-Dimethylbenzimidazole,5,6-二甲基苯并咪唑	Others; Endogenous Metabolite	Metabolism; Others
	5,6-Dimethyl-1H-benzo[d]imidazole (5,6-Dimethylbenzimidazole) 是内源性代谢产物的一种。
T4753	Imidazoleacetic acid hydrochloride I4AA,(4-Imidazolyl)acetic acid hydrochloride,4-咪唑乙酸盐酸盐,4-Imidazoleacetic acid hydrochloride	Endogenous Metabolite; Antibiotic	Metabolism; Microbiology/Virology
	Imidazoleacetic acid hydrochloride (I4AA) 是咪唑衍生物，具有潜在的抗结核性能。它还用于制备β-分泌酶的酰基胍抑制剂。
T75612	α-Glucosidase-IN-24
	α-Glucosidase-IN-24 (Compound 13) 是一种α-Glucosidase 抑制剂，IC50为 451 μM，可以从Swertia kouitchensis 中分离得到。
TN4456	Lucidadiol	AChR; HSV	Microbiology/Virology; Neuroscience
	Lucidadiol exhibits butyrylcholinesterase-inhibitory activity at concentrations up to 200 uM, it also possesses inhibitory activity against acetylcholinesterase (AChE) with the percentage inhibition at 100 uM. Lucidadiol shows antiviral activity against i
T38268	Validamycin A
	Validamycin A is an antifungal agent used to protect rice plants against sheath blight caused by the pathogenic fungus, R. solani, due to its ability to inhibit trehalase, a trehalose-hydrolizing enzyme (Ki = 1.9 nM; IC50 = 0.7 μM). It is also effective against the growth and sporulation of R. cerealis, F. culmorum, and other fungi. This compound has also been used to study trehalase activity and trehalose biosynthesis.
T80713	α-Glucosidase-IN-37
	α-Glucosidase-IN-37（Compound 11）展示出中等水平的抑制作用，能够抑制LPS诱导的NO产生，并在巨噬细胞中表现出23.7 μM的IC50值。该化合物对α-Glucosidase的抑制活性相对较弱。
TN3653	Cimidahurinine	BCL; ROS	Apoptosis; Immunology/Inflammation
	Cimidahurinine can attenuate Doxorubicin (DOX)-induced cardiotoxicity in a dose-dependent manner with EC50 values of 45.79 uM; it protects against cardiotoxicity by decreasing reactive oxygen species (ROS) accumulation and downregulating apoptosis-related Bax/Bcl-2 proteins.
T7731	Validamine
	Validamine is a natural pseudo-aminosugar.
T38415	Adenosine 5′-monophosphoramidate sodium
	Adenosine 5′-monophosphoramidate sodium is a derivative of adenosine used as an intermediate for nucleotide synthesis. It significantly influences the accumulation of cyclic AMP.
TN4232	Hybridaphniphylline B	Others	Others
	Hybridaphniphylline B is a natural product from Daphniphyllum longeracemosum.
T75637	Demethylcantharidate disodium
	Demethylcantharidate disodium 是一种内源性代谢产物，能通过诱导内质网应激来促进肝癌细胞的凋亡，并且对多种类型的癌症展现出良好的抗癌活性。
T81660	Nocarimidazole A
	Nocarimidazole A，一种来源于海洋放线菌Nocardiopsis的白色无定形固体生物碱，具紫外线活性。
T67657	Imidazol-1-yl-acetic acid
	Imidazol-1-yl-acetic acid 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 T67657，CAS号为 22884-10-2。
T81131	Solidagolactone II
	Solidagolactone II is a clerodane diterpene isolated from the plant Solidago virgaurea L.
T2S0605	Liquidambaric lactone	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Liquidambaric lactone 是一种分离自Euonymus grandiflorusWall 中的化合物。
T75576	Solidagonic acid
	Solidagonic acid 通过促进异常单极纺锤体向双极纺锤体的转变来抑制 HSET 运动活动。Solidagonic acid 抑制裂殖酵母细胞死亡，并使有丝分裂纺锤体从单极形态逆转为双极形态。Solidagonic acid 对 Lactuca sativaL. 和 Lolium multiflorumLam 的幼苗具有生长抑制活性。
TN7002	Methyl linolelaidate
	Methyl linolelaidate is a natural product.
T4S1672	Cimicidanol 3-O-alpha-L-arabinoside
	Cimicidanol 3-O-alpha-L-arabinoside是一种天然产物，属于毛茛科升麻属，其产品编号为 T4S1672，CAS号为 161207-05-2。Cimicidanol 3-O-alpha-L-arabinoside可用作对照参考。
T13735	Imidazoleacetic acid Imidazolyl-4-acetic acid	Others	Others
	Imidazoleacetic acid, an endogenous ligand, stimulates imidazole receptors.
T83026	Antioxidant agent-18
	Antioxidant agent-18（compound 5）为一种从银杏（Ginkgo biloba）中提取的黄酮醇苷，展现出显著的抗氧化特性。本化合物能有效清除DPPH自由基（IC50: 15.8 μM），同时具有还原细胞色素c的能力（IC50: 14.7 μM）。
TN4457	Lucidal	Others	Others
	Lucialdehyde C (Lucidal) exhibits potent cytotoxicity against LLC, T-47D, Sarcoma 180, and Meth-A tumor cells with ED(50) values of 10.7, 4.7, 7.1, and 3.8 microg/ml, respectively.
TN4215	Hispidanin B	Others	Others
	Hispidanin B shows significant cytotoxicities against tumor cell lines SGC7901, SMMC7721, and K562, with IC50 values of 10.7, 9.8, and 13.7 uM, respectively.
T75504	Xanthine oxidase-IN-8
	Xanthine oxidase-IN-8 (Icarisids J) (Compound 7) 是一种 XOD 抑制剂，IC50值为 29.71 μM。
T75505	Xanthine oxidase-IN-9
	Xanthine oxidase-IN-9 (Icarisids E) (Compound 2)，一种黄嘌呤氧化酶 (XOD) 高效抑制剂，具有31.81 μM 的 IC50 值。
T81768	Molluscicidal agent-1
	Molluscicidal agent-1 (Compound 3)为从S. vesicaria分离得到的皂苷类化合物。
T83031	Antioxidant agent-10
	Antioxidant agent-10 (Compound 3)，其DPPH清除活性属于中等，具有EC50值为33.2 μg/mL。
TN4231	Hybridaphniphylline A	Others	Others
	Hybridaphniphylline A is a natural product from Daphniphyllum longeracemosum.
T38241	2-Aminoimidazole
	2-Aminoimidazole is a potent antibiofilm agent and adjuvant to antimicrobial treatments, which effectively disrupts bacterial self-protection mechanisms by inhibiting biofilm formation and genetically-encoded antibiotic resistance traits. Additionally, 2-Aminoimidazole acts as a weak noncompetitive inhibitor of human arginase I, with a Ki value of 3.6 mM[1][2][3].
T83029	Antioxidant agent-14
	Antioxidant agent-14, 山柰酚糖苷化合物，源自芥菜叶分离提取。
TN5218	Valerosidate	Others	Others
	Valerosidate is a natural product from Valeriana jatamansi.
T13820	Pi-Methylimidazoleacetic acid	Others	Others
	Pi-Methylimidazoleacetic acid is a potential neurotoxin.
TN4066	Floridanine	Others	Others
	Floridanine是一种天然产物，属于菊科多榔菊属，其产品编号为 TN4066，CAS号为 16958-31-9。Floridanine可用作对照参考。
T81130	Solidagolactone III
	Solidagolactone III，一种从Solidago属植物中分离得到的活性化合物。
TN3788	Decursidate	Others	Others
	Decursidate是一种天然产物，属于伞形科前胡属，其产品编号为 TN3788，CAS号为 272122-56-2。Decursidate可用作对照参考。

天然产物

Cat.No: T7544

Synonym: 岩藻多糖

Target: Others

2,4,5-Tribromoimidazole

Cat.No: TN7167

Synonym: 2,4,5-三溴咪唑,2,4,5-Tribromo-1H-imidazole

Target: Others

5-Amino-3H-imidazole-4-Carboxamide

Cat.No: T1705

Synonym: 4-Amino-5-imidazolecarboxamide,AICA,4-氨基-5-咪唑甲酰胺,5-Aminoimidazole-4-carboxamide

Target: Endogenous Metabolite

Cat.No: T19357

Synonym: Hyaluronate 4-glycanohydrolase,Hyaluronoglucosaminidase,透明质酸酶

Target: Others

5-[(1H-indol-3-yl)methylidene]imidazolidine-2,4-dione

Cat.No: TN7149

Synonym: (4Z)-4-(1H-indol-3-ylmethylidene)-4H-imidazole-2,5-diol,(5Z)-5-(1H-indol-3-ylmethylidene)imidazolidine-2,4-dione

Target: Others

Cat.No: T5202

Synonym: Glyoxaline,1,3-Diaza-2,4-cyclopentadiene,1,3-diazole,咪唑

Target: Others

Cat.No: T1556

Synonym: Tiberal,Ornidazolum,NSC 95075,Ro 7-0207,奥硝唑

Target: Antibacterial, Antibiotic, Parasite

Cat.No: T1506

Synonym: Adenine Arabinoside,阿糖腺苷,9-β-D-Arabinofuranosyladenine,Vira-A,Arabinosyladenine,Ara-A

Target: Nucleoside Antimetabolite/Analog, Tyrosine Kinases, DNA/RNA Synthesis, Antibiotic, HSV

Sodium Demethylcantharidate

Cat.No: T2736

Synonym: Sodium norcantharidin,去甲斑蝥酸钠

Target: Others, Endogenous Metabolite

Methyl deacetylasperulosidate

Cat.No: T5735

Synonym: Deacetyl asperulosidic acid methyl ester,6α-Hydroxygeniposide,去乙酰车叶草苷酸甲酯

Target: Others

Cat.No: T6194

Synonym: 非达米星,Tiacumicin B,OPT-80,Clostomicin B1,PAR-101

Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T1079

Synonym: Flagyl,Metronidazol,甲硝唑,Anagiardil

Target: Apoptosis, NADPH, Hydrogenase, Antibacterial, Antibiotic, Parasite, Antifection

Methyl arachidate

Cat.No: T7958

Synonym: 花生酸甲酯,Methyl Icosanoate

Target: Others, Aminopeptidase

5,6-Dimethyl-1H-benzo[d]imidazole

Cat.No: T4824

Synonym: 5,6-Dimethylbenzimidazole,5,6-二甲基苯并咪唑

Target: Others, Endogenous Metabolite

Imidazoleacetic acid hydrochloride

Cat.No: T4753

Synonym: I4AA,(4-Imidazolyl)acetic acid hydrochloride,4-咪唑乙酸盐酸盐,4-Imidazoleacetic acid hydrochloride

Target: Endogenous Metabolite, Antibiotic

α-Glucosidase-IN-24

Cat.No: T75612

Cat.No: TN4456

Target: AChR, HSV

Cat.No: T38268

α-Glucosidase-IN-37

Cat.No: T80713

Cat.No: TN3653

Target: BCL, ROS

Cat.No: T7731

Adenosine 5′-monophosphoramidate sodium

Cat.No: T38415

Hybridaphniphylline B

Cat.No: TN4232

Target: Others

Demethylcantharidate disodium

Cat.No: T75637

Nocarimidazole A

Cat.No: T81660

Imidazol-1-yl-acetic acid

Cat.No: T67657

Solidagolactone II

Cat.No: T81131

Liquidambaric lactone

Cat.No: T2S0605

Target: HIV Protease

Solidagonic acid

Cat.No: T75576

Methyl linolelaidate

Cat.No: TN7002

Cimicidanol 3-O-alpha-L-arabinoside

Cat.No: T4S1672

Imidazoleacetic acid

Cat.No: T13735

Synonym: Imidazolyl-4-acetic acid

Target: Others

Antioxidant agent-18

Cat.No: T83026

Cat.No: TN4457

Target: Others

Cat.No: TN4215

Target: Others

Xanthine oxidase-IN-8

Cat.No: T75504

Xanthine oxidase-IN-9

Cat.No: T75505

Molluscicidal agent-1

Cat.No: T81768

Antioxidant agent-10

Cat.No: T83031

Hybridaphniphylline A

Cat.No: TN4231

Target: Others

2-Aminoimidazole

Cat.No: T38241

Antioxidant agent-14

Cat.No: T83029

Cat.No: TN5218

Target: Others

Pi-Methylimidazoleacetic acid

Cat.No: T13820

Target: Others

Cat.No: TN4066

Target: Others

Solidagolactone III

Cat.No: T81130

Cat.No: TN3788

Target: Others

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