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64

抑制剂 & 化合物

66

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T37379	Protectin D1 Neuroprotectin D1,NPD1	Akt; PI3K	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	Protectin D1 (Neuroprotectin D1) 是神经细胞产生的神经保护素，是一种潜在的心脏保护剂。Protectin D1 通过调节 PI3K/AKT 信号通路缓解心肌缺血/再灌注损伤，抑制咪喹莫特诱导的银屑病样皮肤炎症。
T12684	Radioprotectin-1 5-chloro-2-[4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butylsulfamoyl]benzoic acid	LPA Receptor	GPCR/G Protein
	Radioprotectin-1 是特异性的 LPA2 激动剂，对小鼠 LPA2 GPCR 的 EC50 为 25 nM，具有辐射保护和辐射缓解作用。
T66294	Protected meropenem
	Protected meropenem 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66294，CAS号为 96036-02-1。
T24529	Neuroprotectant-7 Neuroprotectant7
	Neuroprotectant-7 is a neuroprotectant for Alzheimer's disease. It displays significant neuroprotection and antioxidative properties. It also can cross the blood-brain barrier.
T36043	17(R)-Protectin D1 17(R)-Protectin D1
	17(R)-Protectin D1 is an aspirin-triggered epimer of the specialized pro-resolving mediator protectin D1 .1It decreases leukotriene B4-induced transendothelial migration of human polymorphonuclear (PMN) neutrophils when used at concentrations ranging from 0.1 to 10 nM. 17(R)-Protectin D1 (0.01-10 ng) reduces the recruitment of neutrophils in a mouse model of TNF-α-induced peritonitis. 1.Serhan, C.N., Fredman, G., Yang, R., et al.Novel proresolving aspirin-triggered DHA pathwayChem. Biol.18(18)97...
T25148	beta-Neuroprotectin Ala-asp-leu-ile-ala-tyr-leu-NH2
	beta-Neuroprotectin is a (3H)TCP binding inhibitor and provides protection against NMDA mediated neuronal cell death at low concentration.
TNU0945	5'-Protected 2,2'-anhydrouridine
	Nucleoside Derivatives - Anhydro-nucleosides; Protected nucleosides with NH2/OH group
T12059L	Mitoquinone mesylate MitoQ mesylate,米托蒽醌甲磺酸盐,MitoQ10 mesylate	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Mitoquinone mesylate (MitoQ10 mesylate) 是可防止氧化损伤的抗氧化剂，靶向TPP 的线粒体。
T15005	CP-66948	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	CP-66948 是一种有效的 histamine H2 受体拮抗剂，对胃酸分泌有抑制作用，可用于保护胃黏膜和肠粘膜。
T19805	Benoxacor BRN-4190275,解草酮,BRN 4190275,BRN4190275	Others	Others
	Benoxacor (BRN-4190275) 是一种惰性农业化学品。它作为一种除草剂安全剂，可保护作物免受除草剂毒性。
T11318	Dopexamine hydrochloride 盐酸多培沙明,FPL60278AR	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Dopexamine hydrochloride (FPL60278AR) 是β2肾上腺素能受体激动剂。
T29670	ADR-925 ICRF198,ICRF-198,ADR 925,ICRF 198,ADR925	Endogenous Metabolite	Metabolism
	ADR-925 (ICRF 198) 是右雷佐生的一种活性螯合铁代谢物，具有使新生大鼠心肌细胞免受阿霉素诱导的损伤的能力。
T20982	Sodium 3-nitrobenzenesulfonate	Others	Others
	Sodium 3-nitrobenzenesulfonate 是一种温和的氧化剂。 Sodium 3-nitrobenzenesulfonate 在轧染印花或蒸汽印花时可以保护色光，并抵消还原物质的作用。
T30579	BRD4097	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	BRD4097是HDAC1/2/3/8检测中的阴性对照品,是一种选择性组蛋白去乙酰化酶（HDAC3）抑制剂，可用于保护b 细胞和改善胰岛素抵抗，有助于促进认知功能和增强学习和记忆的形成。
T6623	Oxibendazole	Apoptosis; Parasite	Apoptosis; Microbiology/Virology
	Oxibendazole 是一种苯并咪唑驱虫药，用于防止马和一些家养宠物的蛔虫、圆线虫、线虫、蛲虫和肺虫感染。。它可诱导细胞凋亡，具有抗癌和抗炎活性。
T19859	Nicosulfuron Milagro,Accent,Motivell,烟嘧磺隆	Others	Others
	Nicosulfuron (Milagro) 是一种磺酰脲类的选择性除草剂，常用作出苗后的除草剂，保护玉米作物免受杂草的侵害。它也能够降低乙酰乳酸合酶的活性。
T37496L	Alamandine TFA	RAAS	Endocrinology/Hormones
	Alamandine TFA 是肾素-血管紧张素系统 (RAS) 的成员，是一种血管活性肽，是 G 蛋白偶联受体 MrgD 的内源性配体。它通过抗高血压作用来保护肾脏和心脏。
T13633	D-Phenothrin (-)-trans-Phenothrin,右旋苯醚菊酯	Parasite	Microbiology/Virology
	D-Phenothrin ((-)-trans-Phenothrin) 是一种口服有效的 II 型合成拟除虫菊酯，广泛用于杀死昆虫，蚊子和人类虱子。它还用于兽医，保护农作物和控制动物上的害虫。
TP1219	Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate ANP (1-28), human, porcineANP(1-28)
	Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate 是颗粒鸟苷酸环化酶的刺激剂，已被发现通过增加环鸟苷单磷酸的合成来保护分离的心肌细胞免受复氧诱导的高收缩。Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate 也有助于在反复运动期间刺激脂解，并在运动期间控制脂解。
T29473	6-Hydroxyadenosine
	6-Hydroxyadenosine can protect cells from apoptosis.
T33611	N-Carbethoxyhistidine
	N-Carbethoxyhistidine can be used to protect amine functional groups.
T27372	FR-168888 mesylate FR-168888,FR-168888 Free Base,FR168888,FR 168888
	FR-168888, a new Na+/H+ exchange inhibitor, can protect the heart from arrhythmia and myocardial cell death in ischemic and reperfused situations.
T15671	KU-32	HSP	Cytoskeletal Signaling; Metabolism
	KU-32 is a novel and novobiocin-based Hsp90 inhibitor. It can protect against neuronal cell death.
T31958	Glycine-pentagastrin Glycine pentagastrin,Boc-gly-trp-met-asp-phe-NH2,Tbgtmap
	Glycine-pentagastrin can enhance gastric mucosal defence mechanisms against acid and protect the gastric mucosa from experimental injury.
T0371L	Gliquidone sodium
	Gliquidone sodium is a hypoglycemic sulfonylurea which may protect the liver from injury from diabetes.
T13243	Ubiquinol Ubiquinol-10,CoQH2-10	Others	Others
	Ubiquinol is a reduced form of coenzyme Q10 (CoQ10) and is a potent antioxidant that has the capacity to protect Vitamin E.
T78518	Prochloraz manganese
	Prochloraz manganese为用于农业工业的抗真菌剂。
T68884	Aplysin
	Aplysin is an antineoplastic agent. Aplysin has been shown to suppress breast cancer cell activity via inhibition of the PI3K/AKT/FOXO3a pathway. Aplysin has also been shown to protect hepatocytes against oxidative damage.
T75368	MTSEA-Fluorescein
	MTSEA-Fluorescein 是一种可用于离子通道研究的荧光探针。储存方式：避光。
T16155	MSN-125	Akt	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	MSN-125 effectively inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons protect primary neurons against glutamate excitotoxicity. MSN-125 is an effective Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochond
T71240	AS 703026
	AS 703026 has been shown to inhibit LPS-induced TNFα production in macrophages/monocytes as well as protect from LPS-induced endotoxin shock. AS 703026 may be useful as an anti-inflammatory therapy for COPD patients.
T70278	FR-168888 free base
	FR-168888 free base is a new Na+/H+ exchange inhibitor. FR-168888 has a strong inhibitory effect on Na+/H+ exchange and has been shown to protect the heart from arrhythmia and myocardial cell death in ischemic and reperfused situations.
T71053	AHR-5333 mandelate
	AHR-5333 mandelate is an anti-allergy compound which has been shown to protect against antigen-induced anaphylactic collapse and ascaris antigen-induced skin hypersensitivity. AHR-5333 mandelate has also been shown to inhibit 5-HETE, LTB4 and LTC4 synthesis.
T28047	Mitoquinone-cyclodextrin MitoQ10,Mitoubiquinone mesylate,MitoQ-10,MitoQ,Mito Q10,Mitoquinone mesylate-cyclodextrin
	Mitoquinone-cyclodextrin is a 1:1 molar ratio complex of Mitoquinone mesylate with cyclodextrin. Mitoquinone mesylate is a mitochondria-targeted antioxidant designed to accumulate within mitochondria in vivo in order to protect against oxidative damage. M
TP1338	Neuropeptide Y (29-64), amide, human TFA
	Neuropeptide Y (29-64), amide, human (TFA) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.It is showed that Neuropeptide Y (29-64), amide, human (TFA) is able to protect cortical neurons from Aβ25-35 t
TP2296	TLQP-21	Others	Others
	TLQP 21 is a VGF-derived peptide. TLQP 21 can protect cerebellar granule cells (CGCs) from serum and potassium deprivation-induced apoptosis and increases energy expenditure and prevents early phase diet-induced diabetes.
T40468	Arimoclomol citrate Arimoclomol citrate,BRX-220 citrate
	Arimoclomol citrate (BRX-220 citrate) is a heat shock protein (HSP) co-inducer that acts by enhancing Hsp expression and directly impacting protein aggregation, clearance of misfolded assemblies, and the proteasome-ubiquitin system. This compound is known for its ability to protect motor neurons.
T38312	L-Cysteine-glutathione disulfide
	L-Cysteine-glutathione disulfide, a glutathione derivative endogenous to mammalian cells, is comprised of the oxidized form of free glutathione tripeptide linked via a disulfide bond to L-cysteine. It has been shown to protect mice against acetaminophen-induced hepatotoxicity.
TP1620	Cyclic MKEY
	MKEY, a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, has been shown to protect against atherosclerosis and aortic aneurysm formation by mediating inflammation, but whether it modulates neuroinflammation and brain injury has not
TP1075	AUNP-12 TFA (1353563-85-5 free base) AUNP-12 TFA,NP-12 TFA
	AUNP-12 TFA (NP-12 TFA) is a polypeptide antagonist in the pd-1 signaling pathway, which has the same antagonistic effect on pd-l1 and pd-l2, and can protect the proliferation and effector function of lymphocytes.
T35699	Fosetyl-aluminum
	0 [1]. Fan Z, Jia S, Ding N, et al. Determination of Fosetyl-Aluminium by Ion-Pair Reversed Phase-High Performance Liquid Chromatography With Evaporative Light Scattering Detection. Se Pu. 2009;27(6):849‐851. [2]. TüRK LMEZ , et al. Activity of metalaxyl-M+mancozeb, fosetyl-Al, and phosphorous acid against Phytophthora crown and root rot of apricot and cherry caused by Phytophthora palmivora. Plant Protect. Sci., 53: 216-225.
T36623	Antileukinate
	Antileukinate is a synthetic hexapeptide with an acetylated amino terminus and an amidated carboxyl terminus that inhibits the binding of CXC chemokines to the chemokine receptor CXCR2. It inhibits IL-8 binding to neutrophils (Ki = 2.7-13 μM), prevents neutrophil chemotaxis and β-glucuronidase release, and blocks IL-8-induced skin edema in rabbits. At 53 mg/kg, antileukinate has been shown to protect mice against acute pancreatitis and associated lung injury.
T75857	LL-37, human TFA
	LL-37, human TFA 是一种由37个氨基酸残基组成的两亲性抗菌肽，源自组织蛋白酶，具备广谱抗菌活性。该化合物有助于防护角膜避免感染，同时调节伤口的愈合过程。
T60700	Butabindide
	Butabindide (UCL-1397) 是三肽肽酶II (TPP II)的选择性抑制剂，对 TPP I 和TPP II 的Ki 值分别为 10 μM 和 7 nM。Butabindide 抑制 TPP II 以保护 CCK-8 免于失活。
T81828	MDYYFEER
	MDYYFEER 是源自 C-藻蓝蛋白胰酶水解产物的抗氧化活性肽，能有效清除 DPPH 及 ABTS 自由基，并能保护斑马鱼幼虫免受 H2O2 诱导的氧化损害。
T75864	Calcineurin autoinhibitory peptide TFA
	Calcineurin autoinhibitory peptide TFA 为选择性Ca2+/钙调蛋白依赖性蛋白磷酸酶（钙调神经磷酸酶）抑制剂，IC50约为10 μM。该化合物能够保护神经元不受兴奋性神经元死亡影响。
T75341	Biotin-16-dUTP trisodium
	Biotin-16-dUTP trisodium（Biotin-16-deoxyuridine-5'-triphosphate trisodium）可以通过酶促方式掺入DNA/cDNA中，作为其天然对应物dTTP的替代品。这种化合物主要用于生产用于多种检测应用的生物素化DNA探针。储存条件需避光。
T75372	BODIPY FL Thapsigargin
	BODIPY FL Thapsigargin 作为一种高效绿色荧光染料，主要抑制细胞内肌浆/内质网中的serca型Ca2+泵。其应用焦点在于探究Thapsigargin在活细胞中的结合位置。储存需避光处理。
T73936	HKSOX-1 (5/6-mixture)
	HKSOX-1 是一种荧光探针，用于成像和检测活细胞以及体内的内源性超氧化物。 HKSOX-1 对超氧阴离子自由基具有极好的选择性和敏感性。储存方式：避光。
T37534	DMPAC-Chol
	DMPAC-Chol is a cationic cholesterol derivative that has been used in liposome formation for gene transfection. Liposomes containing DMPAC-chol bind to DNA in a band shift assay and protect against serum nuclease degradation of DNA when used at lipsome:DNA ratios ranging from 2.5:1 to 10:1 w/w. DMPAC-Chol-containing liposomes also reduce viability of HepG2 cells by 63% when used at a concentration of 37.5 μg/ml.

化合物

Cat.No: T37379

Synonym: Neuroprotectin D1,NPD1

Target: Akt, PI3K

Radioprotectin-1

Cat.No: T12684

Synonym: 5-chloro-2-[4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butylsulfamoyl]benzoic acid

Target: LPA Receptor

Protected meropenem

Cat.No: T66294

Neuroprotectant-7

Cat.No: T24529

Synonym: Neuroprotectant7

17(R)-Protectin D1

Cat.No: T36043

Synonym: 17(R)-Protectin D1

beta-Neuroprotectin

Cat.No: T25148

Synonym: Ala-asp-leu-ile-ala-tyr-leu-NH2

5'-Protected 2,2'-anhydrouridine

Cat.No: TNU0945

Mitoquinone mesylate

Cat.No: T12059L

Synonym: MitoQ mesylate,米托蒽醌甲磺酸盐,MitoQ10 mesylate

Target: Reactive Oxygen Species

Cat.No: T15005

Target: Histamine Receptor

Cat.No: T19805

Synonym: BRN-4190275,解草酮,BRN 4190275,BRN4190275

Target: Others

Dopexamine hydrochloride

Cat.No: T11318

Synonym: 盐酸多培沙明,FPL60278AR

Target: Adrenergic Receptor

Cat.No: T29670

Synonym: ICRF198,ICRF-198,ADR 925,ICRF 198,ADR925

Target: Endogenous Metabolite

Sodium 3-nitrobenzenesulfonate

Cat.No: T20982

Target: Others

Cat.No: T30579

Target: HDAC

Cat.No: T6623

Target: Apoptosis, Parasite

Cat.No: T19859

Synonym: Milagro,Accent,Motivell,烟嘧磺隆

Target: Others

Cat.No: T37496L

Target: RAAS

Cat.No: T13633

Synonym: (-)-trans-Phenothrin,右旋苯醚菊酯

Target: Parasite

Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate

Cat.No: TP1219

Synonym: ANP (1-28), human, porcineANP(1-28)

6-Hydroxyadenosine

Cat.No: T29473

N-Carbethoxyhistidine

Cat.No: T33611

FR-168888 mesylate

Cat.No: T27372

Synonym: FR-168888,FR-168888 Free Base,FR168888,FR 168888

Cat.No: T15671

Target: HSP

Glycine-pentagastrin

Cat.No: T31958

Synonym: Glycine pentagastrin,Boc-gly-trp-met-asp-phe-NH2,Tbgtmap

Gliquidone sodium

Cat.No: T0371L

Cat.No: T13243

Synonym: Ubiquinol-10,CoQH2-10

Target: Others

Prochloraz manganese

Cat.No: T78518

Cat.No: T68884

MTSEA-Fluorescein

Cat.No: T75368

Cat.No: T16155

Target: Akt

Cat.No: T71240

FR-168888 free base

Cat.No: T70278

AHR-5333 mandelate

Cat.No: T71053

Mitoquinone-cyclodextrin

Cat.No: T28047

Synonym: MitoQ10,Mitoubiquinone mesylate,MitoQ-10,MitoQ,Mito Q10,Mitoquinone mesylate-cyclodextrin

Neuropeptide Y (29-64), amide, human TFA

Cat.No: TP1338

Cat.No: TP2296

Target: Others

Arimoclomol citrate

Cat.No: T40468

Synonym: Arimoclomol citrate,BRX-220 citrate

L-Cysteine-glutathione disulfide

Cat.No: T38312

Cat.No: TP1620

AUNP-12 TFA (1353563-85-5 free base)

Cat.No: TP1075

Synonym: AUNP-12 TFA,NP-12 TFA

Fosetyl-aluminum

Cat.No: T35699

Cat.No: T36623

LL-37, human TFA

Cat.No: T75857

Cat.No: T60700

Cat.No: T81828

Calcineurin autoinhibitory peptide TFA

Cat.No: T75864

Biotin-16-dUTP trisodium

Cat.No: T75341

BODIPY FL Thapsigargin

Cat.No: T75372

HKSOX-1 (5/6-mixture)

Cat.No: T73936

Cat.No: T37534

Cat. No.	Product Name	Target	Signaling Pathways
T2S1720	Huperzine B	AChE	Neuroscience
	Huperzine B 是一种从 Huperzia serrata 中分离出的石蒜生物碱，也是一种高度选择性的乙酰胆碱酯酶抑制剂，可以用于改善阿尔茨海默氏病。
T80778	weak Hepatoprotective agent-1
	Weak Hepatoprotective agent-1 (Compound 11)，一种从Arctium lappa L. 分离得到的天然产物，在10 μM浓度下具有弱肝保护活性。
TN1038	Galgravin	Apoptosis	Apoptosis
	Galgravin 是望春花中的一种天然产物，具有抗炎和体外细胞毒活性，能诱导白血病细胞凋亡。
T5S2195	Sibiricose A5 西伯利亚远志糖A5	Dehydrogenase	Metabolism
	Sibiricose A5 是一种寡糖酯，分离自Polygalae Radix，具有抗氧化作用。
TN2286	Tsugaric acid A	NO Synthase	Immunology/Inflammation
	Tsugaric acid A 能够显著抑制超氧阴离子的形成，还可以保护人类角质形成细胞，使其免受紫外线 B 诱导的损害。
T5235	5-Methoxy-DL-tryptophan	Others; Endogenous Metabolite	Metabolism; Others
	5-Methoxy-DL-tryptophan 是内源性代谢产物的一种。
T4396	Officinalisinin I	Others	Others
	Officinalisinin I 是一种甾体皂苷，分离自 Anemarrhena asphodeloides。
TN2436	4-methyl-6-phenyl-2H-pyranone 4-methyl-6-phenyl-2H-pyranone	Mitochondrial Metabolism	Metabolism
	4-methyl-6-phenyl-2H-pyranone 源自黄芩黄芩，可改善线粒体功能以保护星形胶质细胞免受过氧化氢诱导的毒性。
T6S0444	Salvianolic acid A 丹酚酸 A,Dan Phenolic Acid A	MMP	Proteases/Proteasome
	Salvianolic acid A (Dan Phenolic Acid A) 能够提高抑制基质金属钛酶 9 和抗炎作用，进而保护血脑屏障。
T6S0659	Rhynchophylline 钩藤碱,Rhynchophyllin,Rhyncophylline,Mitrinermine,Mitrinermin	Calcium Channel; NF-κB	Membrane transporter/Ion channel; Metabolism; NF-κB
	Rhynchophylline (Mitrinermine) 是一种生物碱类化合物，从钩藤中分离得到，具有很高的生物活性，被广泛用于抗炎、神经保护等方面的研究。
T3S1628	Vitexin-4''-O-glucoside Vitexin -4''-O-glucoside,牡荆素-4''-O-葡萄糖苷	Others	Others
	Vitexin-4''-O-glucoside (Vitexin -4''-O-glucoside) 是一种从Crataegus pinnatifida 叶片中得到的类黄酮成分。
T3S0137	Bavachalcone	Antibacterial; Antibiotic	Microbiology/Virology
	Bavachalcone 是从补骨脂中分离的化合物，广泛用于中药，具有抗生素和抗癌等活性。
TN3601	Carminic acid	ROS	Immunology/Inflammation
	Carminic acid 是天然红色色素，是球虫染料家族中的一种。
T3913	Saikosaponin D	Estrogen Receptor/ERR; NF-κB; Antibacterial; STAT	Endocrinology/Hormones; JAK/STAT signaling; Microbiology/Virology; NF-κB; Stem Cells
	Saikosaponin D 是一种从柴胡中分离到的三萜皂苷类天然产物，具有抗炎，抗菌，抗肿瘤，抗过敏作用。它抑制 selectin，STAT3和 NF-kB 的活性，活化estrogen receptor-β。
T4S2084	3'-Methoxypuerarin 3'-甲氧基葛根素,3’- Methoxy Puerarin	Antioxidant	oxidation-reduction
	3'-Methoxypuerarin 是一种提取自葛根中的异黄酮，具有神经元保护作用。
T3S0401	Piceatannol 3'-O-glucoside 白皮杉醇 3'-O-葡萄糖苷,Piceatannol 3-glycoside,Quzhaqigan,曲札茋苷、白皮杉醇-3'-O-葡萄糖苷	Arginase; NO Synthase	Immunology/Inflammation
	Piceatannol 3'-O-glucoside (Piceatannol 3-glycoside) 是大黄的一种活性成分，通过抑制精氨酸酶活性激活内皮细胞一氧化氮合酶，抑制Arginase I 和Arginase II，IC50值分别为 11.22 和 11.06 μM。它可增加肺血氧分压，减少肺间质水肿，从而保护肺损伤。
T3900	Emodin-8-glucoside 大黄素-8-β-D-吡喃葡萄糖苷,Emodin glucoside B,Anthraglycoside B	Others	Others
	Emodin-8-glucoside (Anthraglycoside B) 是从芦荟中分离出的蒽醌衍生物，与 DNA 的小沟结合。它具有保护缺血和再灌注引起的局灶性脑损伤的作用。它直接刺激成骨细胞的细胞增殖和分化。
T6S1930	Schisanhenol 五味子酚,Schizanhenol,Gomisin-K3	Antioxidant	oxidation-reduction
	Schisanhenol (Schizanhenol) 是一种UGT2B7的抑制剂，是一种天然化合物。
T67319	2',4'-Dimethylacetophenone	Endogenous Metabolite	Metabolism
	2',4'-Dimethylacetophenone 是一种可用于生物研究的化学物。该化合物可用于气相色谱法检测烟草化合物中的醛固酮香气，可以用于保护食品。
T5692	Pyrroloquinoline quinone	Others; Endogenous Metabolite	Metabolism; Others
	Pyrroloquinoline quinone 是氧化还原辅助因子，一种阴离子型氧化还原循环原醌。它是哺乳动物的必需营养素，对免疫功能很重要。它是从嗜甲基细菌的培养物中分离的，也存在于哺乳动物的组织。
PDK0014	3-Methylxanthine	Endogenous Metabolite	Metabolism
	3-Methylxanthine 是一种黄嘌呤衍生物和环磷酸鸟苷（GMP）抑制剂，在豚鼠分离的气管肌肉中测得其IC50值为 920 μM。
T7036	2,4'-Dihydroxybenzophenone	Antioxidant	oxidation-reduction
	2,4'-Dihydroxybenzophenone 可有效保护 C57BL/6J 小鼠免受 APAP 诱导的肝毒性。它对可卡因诱导的小鼠急性肝毒性和神经毒性具有保护作用。其机制可能与其抗氧化活性有关。
T5S2178	Fargesin 辛夷脂素,(+/-)-Fargesin	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Fargesin ((+/-)-Fargesin) 是一种活性新木脂素，从木兰植物中分离得到，具有抗高血压和抗炎活性。
TN1461	(-)-Butin Butin,漆黄素 ( 紫铆素)	Akt; PI3K; Nrf2	Cytoskeletal Signaling; Immunology/Inflammation; PI3K/Akt/mTOR signaling
	(-)-Butin (Butin) 是 Butin 的 S 对映体。其中 Butin 是一种分离自黄檀的心材中的生物活性黄酮类化合物，具有显著的抗血小板、抗氧化、抗炎作用。
T19866	Indican NSC-87517,3-Indoxyl-beta-D-glucopyranoside,3-吲哚基-beta-D-吡喃葡萄糖苷,NSC 87517,NSC87517,Indoxyl-β-D-glucoside	OAT; MRP	Immunology/Inflammation; Membrane transporter/Ion channel
	Indican (Indoxyl-β-D-glucoside) 是吲哚酚的一种糖苷，染料靛蓝和靛玉红的前体。它的主要代谢物是硫酸吲哚酚 (IS)。其中 IS 是尿毒症毒素，是有机阴离子转运蛋白1 (OAT 1)、OAT 3 和多药耐药相关蛋白4 (MRP 4) 的底物/抑制剂。
TN1895	Luteolinidin chloride	CD38	Immunology/Inflammation
	Luteolinidin chloride 是天然的脱氧花青素，分离自苔藓和蕨类植物中。它是一种有效的 CD38 抑制剂，可以保留 eNOS 功能并预防体内内皮功能障碍，同时可以保护心脏免受 I/R 损伤。
T3674	Hydroxysafflor yellow A 藏红花,羟基红花黄色素A,HSYA,Safflomin A	TGF-beta/Smad	Stem Cells
	Hydroxysafflor yellow A (Safflomin A) 是一种黄酮类天然产物，从中药红花中分离得到，具有抗癌作用。
TN6774	Emodin 6-O-β-D-glucoside 大黄素-6-O-β-D-葡萄糖苷,Glucoemodin	Others	Others
	Emodin 6-O-β-D-glucoside (Glucoemodin) 是一种从 Reynoutria japonica 中提取的活性化合物。它具有显著的抗炎和屏障保护活性，可用于研究动脉粥样硬化及糖尿病并发症。
T2A2532	L-Histidine Glyoxaline-5-alanine,L-(-)-Histidine,L-组氨酸,histidine,组氨酸,L-Hisidine	Mitochondrial Metabolism; Endogenous Metabolite	Metabolism
	L-Histidine (L-(-)-Histidine) 是人类生长和组织修复所需的一种半必需氨基酸(儿童应从食物中获得)。 L-Histidine 是线粒体谷氨酰胺转运的抑制剂。
TN2080	Pinoresinol 松脂酚，松脂素,(+)-Pinoresinol	Apoptosis; NF-κB; CDK; p53	Apoptosis; Cell Cycle/Checkpoint; NF-κB
	Pinoresinol ((+)-Pinoresinol) 是一种植物来源的木质素，具有抗炎、保肝和杀真菌活性。它导致 CDK 抑制剂 p21(WAF1/Cip1) 在 mRNA 和蛋白质水平上调，抑制 NF-kappaB 和激活蛋白 1 。
T5S1286	(+)-Columbianetin 二氢山芹醇,(S)-Columbianetin,Columbianetin	Antifungal	Microbiology/Virology
	(+)-Columbianetin ((S)-Columbianetin) 是 Columbianetin 的异构体。其中Columbianetin 是一种植物抗毒素，与芹菜贮藏过程中对病原体的抗性有关，具有良好的抗真菌和抗炎作用。
T2978	Mogroside V	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	Mogroside V 是三萜糖苷，是非糖类甜味剂，甜度比蔗糖甜高300倍。它具有抗氧化，抗糖尿病和抗癌作用。
TC0019	Pregnenolone acetate 孕烯醇酮醋酸酯,3β-Hydroxy-5-pregnen-20-one acetate	Cannabinoid Receptor; Endogenous Metabolite	GPCR/G Protein; Metabolism
	Pregnenolone acetate 是一种强大的神经类固醇，是各种类固醇激素（包括类固醇酮）的主要前体。它作为大麻素 CB1 受体的信号特异性抑制剂，抑制由 CB1 受体介导的四氢大麻酚 (THC) 的作用。它可以保护大脑免受大麻中毒。
TWS1977	Kamebakaurin 尾叶香茶菜丙素,Kamebakaurine	NF-κB	NF-κB
	Kamebakaurin (Kamebakaurine) 是一种提取自Isodon japonicus 中的天然产物，是一种NF-κB 的抑制剂，能够抑制 p50 的 DNA 结合活性。
T3S1068	Oxyresveratrol trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,氧化白藜芦醇,Tetrahydroxystilbene	Tyrosinase; Autophagy; HSV	Autophagy; Microbiology/Virology; Proteases/Proteasome
	Oxyresveratrol (trans-Oxyresveratrol) 是非竞争性酪氨酸酶抑制剂，对蘑菇酪氨酸酶的 IC50值为 1.2 µM。它抑制HSV-1，HSV-2和水痘带状疱疹病毒，具有神经保护作用。它是天然抗氧化剂和自由基清除剂。
T5270	5-Methylcytosine	Others; DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	5-Methylcytosine 是一种存在于真核 DNA 中的甲基化核苷酸碱基。它是由 DNA 甲基转移酶作用形成的表观遗传修饰。
T4S1422	Praeruptorin E 白花前胡素 E,白花前胡素E	Others; Calcium Channel	Membrane transporter/Ion channel; Metabolism; Others
	Praeruptorin E 是白花前胡中的一种主要成分，是钙拮抗剂，pD2′值为 5.2。
T6S1966	Curculigoside Curculigoside A,仙茅苷	Antioxidant; NF-κB; JAK; STAT	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; NF-κB; oxidation-reduction; Stem Cells
	Curculigoside (Curculigoside A) 是仙茅中的主要皂苷，具有显著的抗氧化、抗骨质疏松、抗抑郁和神经保护作用。它通过调节JAK/STAT/NF-κB 信号传导途径，具有抗关节炎作用。
T1660	Silibinin 水飞蓟宾 A,水飞蓟宾,Silibinin A,Silybin,Silymarin I	Reactive Oxygen Species; Autophagy	Autophagy; Immunology/Inflammation; Metabolism; NF-κB
	Silibinin (Silybin) 是水飞蓟的主要活性成分，具有抗癌和化疗预防作用，能抑制细胞增殖和迁移。
TN1362	Afzelin 阿福豆苷,Kaempferol-3-O-rhamnoside	PTEN; p38 MAPK; TNF; Mitochondrial Metabolism; Antibacterial; Prostaglandin Receptor; Autophagy	Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; MAPK; Metabolism; Microbiology/Virology; PI3K/Akt/mTOR signaling
	Afzelin (Kaempferol-3-O-rhamnoside) 具有多种细胞活性，例如 DNA 保护、抗菌、抗氧化和抗炎以及 UV 吸收活性，并且可以通过 UV 吸收和细胞活性的组合保护人体皮肤免受 UVB 引起的损伤。 Afzelin 减轻线粒体损伤，增强线粒体生物合成并降低线粒体自噬相关蛋白、parkin 和 putative kinase 1 的水平。
T3851	Vicenin 2 Vicenin -2,维采宁 2,新西兰牡荆苷	RAAS	Endocrinology/Hormones
	Vicenin 2 来源于广金钱草 (Desmodium styracifolium) 的地上部分。Vicenin 2 是一种血管紧张素转换酶 (ACE) 抑制剂，IC50=43.83 μM。
T6S1740	Nardosinone 苷松新酮,甘松新酮	Others	Others
	Nardosinone 是一个 dbcAMP 和 staurosporine 的神经生成作用增强剂，分离自Nardostachys chinensis 中。Nardosinone 可能成为一种有用的药理学工具，不仅可用于研究神经生长因子 (NGF) 的作用机理，而且可用于研究神经毒性物质的作用机理。
T3414	Morroniside 莫诺苷,奎宁树	Apoptosis; MMP; Pyroptosis	Apoptosis; Immunology/Inflammation; Proteases/Proteasome
	Morroniside 通过抑制神经元凋亡和 MMP9/2 的表达从而发挥神经保护作用，可作为 db/db 小鼠肝脏炎症反应和脂质代谢的调节剂。它通过抑制高血糖和氧化应激表现出对糖尿病肾损伤和人脐静脉内皮细胞的保护作用。
T3795	Corilagin	Apoptosis; TLR; Reverse Transcriptase; Antibacterial; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; Microbiology/Virology
	Corilagin 是一种鞣酸，有抑制 RNA 肿瘤病毒逆转录酶的活性。它抑制金黄色葡萄球菌的生长，MIC 为 25 μg/mL。它有抗肿瘤活性，可用于肝癌和卵巢癌。
T4S2326	Cornuside 7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside	ERK; p38 MAPK; NF-κB; JNK	MAPK; NF-κB
	Cornuside (Comuside) 是从山茱萸的果实中分离出的环烯醚萜苷，可用于炎症疾病的研究和促进血液循环。它通过下调 MAPK 和 NF-κB 信号通路抑制肥大细胞介导的过敏反应，用于炎性过敏性疾病中的潜能。
T13717	Gypenoside XIII	Others	Others
	Gypenoside XIII is belonging to the gypenosides. Gypenosides, extracted from Gynostemma pentaphyllum, protect against cardiovascular diseases, especially atherosclerosis.
TMA0763	Methyl 3,4,5-trimethoxycinnamate	Potassium Channel; Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Methyl 3,4,5-trimethoxycinnamate may protect the heart from arrhythmias via its inhibitory effect on calcium channel.
TMA1409	cis-Mulberroside A	TNF; NOS	Apoptosis; Immunology/Inflammation
	cis-Mulberroside A shows high analgesic and anti-inflammatory activities, it can protect mice against ethanol-induced hepatic damage.
T19496	Oleuroside	Others	Others
	Oleuroside can protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing.
TN3612	Caulophine	Others	Others
	Caulophine has the ability to protect cardiomyocytes from oxidative and ischemic injury through an antioxidative mechanism.
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天然产物

Cat.No: T2S1720

Target: AChE

weak Hepatoprotective agent-1

Cat.No: T80778

Cat.No: TN1038

Target: Apoptosis

Cat.No: T5S2195

Synonym: 西伯利亚远志糖A5

Target: Dehydrogenase

Tsugaric acid A

Cat.No: TN2286

Target: NO Synthase

5-Methoxy-DL-tryptophan

Cat.No: T5235

Target: Others, Endogenous Metabolite

Officinalisinin I

Cat.No: T4396

Target: Others

4-methyl-6-phenyl-2H-pyranone

Cat.No: TN2436

Synonym: 4-methyl-6-phenyl-2H-pyranone

Target: Mitochondrial Metabolism

Salvianolic acid A

Cat.No: T6S0444

Synonym: 丹酚酸 A,Dan Phenolic Acid A

Target: MMP

Rhynchophylline

Cat.No: T6S0659

Synonym: 钩藤碱,Rhynchophyllin,Rhyncophylline,Mitrinermine,Mitrinermin

Target: Calcium Channel, NF-κB

Vitexin-4''-O-glucoside

Cat.No: T3S1628

Synonym: Vitexin -4''-O-glucoside,牡荆素-4''-O-葡萄糖苷

Target: Others

Cat.No: T3S0137

Target: Antibacterial, Antibiotic

Cat.No: TN3601

Target: ROS

Cat.No: T3913

Target: Estrogen Receptor/ERR, NF-κB, Antibacterial, STAT

3'-Methoxypuerarin

Cat.No: T4S2084

Synonym: 3'-甲氧基葛根素,3’- Methoxy Puerarin

Target: Antioxidant

Piceatannol 3'-O-glucoside

Cat.No: T3S0401

Synonym: 白皮杉醇 3'-O-葡萄糖苷,Piceatannol 3-glycoside,Quzhaqigan,曲札茋苷、白皮杉醇-3'-O-葡萄糖苷

Target: Arginase, NO Synthase

Emodin-8-glucoside

Cat.No: T3900

Synonym: 大黄素-8-β-D-吡喃葡萄糖苷,Emodin glucoside B,Anthraglycoside B

Target: Others

Cat.No: T6S1930

Synonym: 五味子酚,Schizanhenol,Gomisin-K3

Target: Antioxidant

2',4'-Dimethylacetophenone

Cat.No: T67319

Target: Endogenous Metabolite

Pyrroloquinoline quinone

Cat.No: T5692

Target: Others, Endogenous Metabolite

3-Methylxanthine

Cat.No: PDK0014

Target: Endogenous Metabolite

2,4'-Dihydroxybenzophenone

Cat.No: T7036

Target: Antioxidant

Cat.No: T5S2178

Synonym: 辛夷脂素,(+/-)-Fargesin

Target: Adrenergic Receptor

Cat.No: TN1461

Synonym: Butin,漆黄素 ( 紫铆素)

Target: Akt, PI3K, Nrf2

Cat.No: T19866

Synonym: NSC-87517,3-Indoxyl-beta-D-glucopyranoside,3-吲哚基-beta-D-吡喃葡萄糖苷,NSC 87517,NSC87517,Indoxyl-β-D-glucoside

Target: OAT, MRP

Luteolinidin chloride

Cat.No: TN1895

Target: CD38

Hydroxysafflor yellow A

Cat.No: T3674

Synonym: 藏红花,羟基红花黄色素A,HSYA,Safflomin A

Target: TGF-beta/Smad

Emodin 6-O-β-D-glucoside

Cat.No: TN6774

Synonym: 大黄素-6-O-β-D-葡萄糖苷,Glucoemodin

Target: Others

Cat.No: T2A2532

Synonym: Glyoxaline-5-alanine,L-(-)-Histidine,L-组氨酸,histidine,组氨酸,L-Hisidine

Target: Mitochondrial Metabolism, Endogenous Metabolite

Cat.No: TN2080

Synonym: 松脂酚，松脂素,(+)-Pinoresinol

Target: Apoptosis, NF-κB, CDK, p53

(+)-Columbianetin

Cat.No: T5S1286

Synonym: 二氢山芹醇,(S)-Columbianetin,Columbianetin

Target: Antifungal

Cat.No: T2978

Target: AMPK

Pregnenolone acetate

Cat.No: TC0019

Synonym: 孕烯醇酮醋酸酯,3β-Hydroxy-5-pregnen-20-one acetate

Target: Cannabinoid Receptor, Endogenous Metabolite

Cat.No: TWS1977

Synonym: 尾叶香茶菜丙素,Kamebakaurine

Target: NF-κB

Cat.No: T3S1068

Synonym: trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,氧化白藜芦醇,Tetrahydroxystilbene

Target: Tyrosinase, Autophagy, HSV

5-Methylcytosine

Cat.No: T5270

Target: Others, DNA/RNA Synthesis, Endogenous Metabolite

Cat.No: T4S1422

Synonym: 白花前胡素 E,白花前胡素E

Target: Others, Calcium Channel

Cat.No: T6S1966

Synonym: Curculigoside A,仙茅苷

Target: Antioxidant, NF-κB, JAK, STAT

Cat.No: T1660

Synonym: 水飞蓟宾 A,水飞蓟宾,Silibinin A,Silybin,Silymarin I

Target: Reactive Oxygen Species, Autophagy

Cat.No: TN1362

Synonym: 阿福豆苷,Kaempferol-3-O-rhamnoside

Target: PTEN, p38 MAPK, TNF, Mitochondrial Metabolism, Antibacterial, Prostaglandin Receptor, Autophagy

Cat.No: T3851

Synonym: Vicenin -2,维采宁 2,新西兰牡荆苷

Target: RAAS

Cat.No: T6S1740

Synonym: 苷松新酮,甘松新酮

Target: Others

Cat.No: T3414

Synonym: 莫诺苷,奎宁树

Target: Apoptosis, MMP, Pyroptosis

Cat.No: T3795

Target: Apoptosis, TLR, Reverse Transcriptase, Antibacterial, Autophagy

Cat.No: T4S2326

Synonym: 7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside

Target: ERK, p38 MAPK, NF-κB, JNK

Gypenoside XIII

Cat.No: T13717

Target: Others

Methyl 3,4,5-trimethoxycinnamate

Cat.No: TMA0763

Target: Potassium Channel, Calcium Channel

cis-Mulberroside A

Cat.No: TMA1409

Target: TNF, NOS

Cat.No: T19496

Target: Others

Cat.No: TN3612

Target: Others

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