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Search Results for " pdgfr-2 "
Targets Recommended: Raf VEGFR c-RET PDGFR c-Kit Drug Metabolite

25

抑制剂 & 化合物

303

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T10157 Regorafénib N-oxyde (M2)

瑞戈非尼杂质 13

Raf; VEGFR; c-RET; PDGFR; c-Kit; Drug Metabolite Angiogenesis; Apoptosis; MAPK; Metabolism; Tyrosine Kinase/Adaptors
Regorafénib N-oxyde M2 是 Regorafenib 的活性代谢物。Regorafenib 是多靶点抑制剂,包括VEGFR1/2/3,PDGFRβ,Kit,RET 和 Raf-1 , IC50分别是 13/4.2/46,22,7,1.5 和 2.5 nM。
T2609 Masitinib

AB1010,马赛替尼

Apoptosis; FAK; c-Fms; FGFR; Bcr-Abl; PDGFR; Src; c-Kit; Hck Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
Masitinib (AB1010) 是生物口服可利用的选择性 c-Kit 抑制剂 (对于人重组c-Kit,IC50=200 nM),它还抑制PDGFRα/β(IC50s=540/800 nM),Lyn(对 LynB 的IC50=510 nM),Lck,较小程度上抑制FGFR3和FAK。它有抗增殖,促凋亡活性,且毒性低。
T4315 Ki20227

N-[4-[(6,7-二甲氧基-4-喹啉基)氧基]-2-甲氧基苯基]-N'-[1-(2-噻唑基)乙基]脲

c-Fms; VEGFR; CSF-1R; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Ki20227 是一种高效的、口服具有活性的、选择性的CSF1R(c-Fms 酪氨酸激酶)抑制剂,对 CSF1R,VEGFR2,c-Kit 和PDGFRβ的IC50分别为 2 nM,12 nM,451 nM 和 217 nM。它可以阻止破骨细胞分化和溶骨性破坏。
T13238 Tyrphostin AG1433

SU1433,AG1433

VEGFR; PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
Tyrphostin AG1433 (AG1433) 是选择性的PDGFRβ和VEGFR-2 (Flk-1/KDR)抑制剂,IC50分别为 5.0 μM 和 9.3 μM。Tyrphostin AG1433有防止血管形成的活性。
T2415 PP121

Apoptosis; VEGFR; Bcr-Abl; PDGFR; Src; mTOR; Hck Angiogenesis; Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
PP121是一种多靶点激酶抑制剂,抑制 PDGFR、Hck、mTOR、VEGFR2、Src、Abl、DNK-PK 的 IC50值分别为2、8、10、12、14、18、60 nM。
T14137 AG 1295

PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
AG 1295 是选择性血小板衍生生长因子受体酪氨酸激酶抑制剂。它能抑制 PDGFR 的自磷酸化,对 EGF 受体的自磷酸化无影响。
T2288 Motesanib

AMG 706,莫特塞尼,莫替沙尼

VEGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Motesanib (AMG 706) 是有效的、ATP 竞争性的 VEGFR1/2/3 的抑制剂,其IC50值为 2 nM/3 nM/6 nM,与对 Kit 的选择性相似,是 PDGFR 和 Ret 的 10 倍多。
T3476 JI-101

CGI-1842,JI 101

VEGFR; PDGFR; Ephrin Receptor Angiogenesis; Tyrosine Kinase/Adaptors
JI-101 (CGI-1842) 是一种有口服活性的多靶点激酶抑制剂,能够抑制VEGFR2PDGFRβ和EphB4,具有抗癌作用。
T15616 JNJ-10198409

3-氟-N-(6,7-二甲氧基-2,4-二氢茚并[1,2-C〕吡唑-3-基苯基胺,JNJ-​10198409

PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
JNJ-10198409 是相对选择性的、ATP 竞争性的、具有口服活性的血小板衍生生长因子受体酪氨酸激酶抑制剂,其IC50=2 nM。它对PDGFR-β激酶 (IC50=4.2 nM) 和PDGFR-α激酶 (IC50=45 nM) 有较好的抑制作用。它是双重机制的抗血管生成和肿瘤细胞的抗增殖剂。
T6079 NVP-ADW742

ADW742,ADW,GSK 552602A

Apoptosis; IGF-1R Apoptosis; Tyrosine Kinase/Adaptors
NVP-ADW742 (ADW) 是一种具有口服活性,选择性的IGF-1R 酪氨酸激酶抑制剂,IC50为 0.17 μM。它抑制胰岛素受体,IC50为 2.8 μM,在肿瘤细胞中诱导多效性抗增殖/促凋亡。
T3570 SU4312

SU 4312,NSC 86429

VEGFR; PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
NSC-86429 是一种 (Z)-SU4312 (SU 4312) 和 (E)-SU4312 的外消旋体。其中(Z)-SU4312 能够抑制 PDGFR 和 FLK-1。(E)-SU4312 能够抑制 PDGFR, FLK-1, EGFR, HER-2, 和 IGF-1R。
T1792L Regorafenib monohydrate

Raf; VEGFR; c-RET; PDGFR; c-Kit; Autophagy Angiogenesis; Apoptosis; Autophagy; MAPK; Tyrosine Kinase/Adaptors
Regorafenib monohydrate 是一种新型口服多激酶抑制剂,对VEGFR1/2/3、PDGFRβ、Kit、RET 和Raf-1的IC50分别为 13、4.2、46、22、7、1.5 和 2.5 nM。
T3463 NVP-ACC789

ACC-789,ZK202650

VEGFR; PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
NVP-ACC789 (ZK202650) 是一种人VEGFR-1,VEGFR-2(鼠VEGFR-2),VEGFR-3 和 PDGFR-β 的抑制剂,它们的 IC50 值分别为 0.38,0.02 (0.23),0.18 和 1.4 μM。
T2288L Motesanib Diphosphate

Motesanib,AMG 706,二磷酸莫替沙尼

VEGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Motesanib Diphosphate (AMG 706) 是一种有效的VEGFR1/2/3的 ATP 竞争性抑制剂,IC50值为 2 nM/3 nM/6 nM,与对 Kit 的选择性相似,是 PDGFR 和 Ret 的 10 倍多。
T3211 Midostaurin

米哚妥林,N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251,苯甲酰基十字孢碱

Others; PKC Chromatin/Epigenetic; Cytoskeletal Signaling; Others
Midostaurin (PKC412) 是一种多靶点蛋白激酶抑制剂,有抗肿瘤活性,对 PKCα/β/γ、Syk、Flk-1、Akt、PKA、c-Kit、c-Fgr、c-Src、FLT3、PDFRβ和VEGFR1/2的IC50值范围为 22 到500 nM 之间。
T6350 CHIR-124

CHIR124,CHIR 124

Apoptosis; GSK-3; FLT; Chk; PDGFR; Src Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; PI3K/Akt/mTOR signaling; Stem Cells; Tyrosine Kinase/Adaptors
CHIR-124 是一种选择性 Chk1抑制剂,IC50值为 0.3 nM,可有效抑制 PDGFR 和 FLT3,IC50值分别为 6.6 nM 和 5.8 nM。
T71576 SIM010603

SIM010603 is a structurally novel, oral, multi-targeted receptor tyrosine kinase inhibitor. SIM010603 inhibited stem cell factor receptor (Kit), vascular endothelial growth factor receptor-2 (VEGFR-2), platelet-derived growth factor receptor-β (PDGFR-β), glial cell line-derived neurotrophic factor receptor (Rearranged during Transfection; RET), and Fms-like tyrosine kinase-3 (FLT3) with IC(50) values between 5.0 and 68.1 nmol/l. SIM010603 inhibited the phosphorylation of PDGFR-β and VEGFR-2. Mor...
T68484 2-MT-63

2-MT 63 is a novel TIE-2 kinase inhibitor that demonstrates unique and improved kinase selectivity compared to other inhibitors known to interact with TIE-2. 2-MT 63 has a good kinase selectivity profile in enzyme assays with >30-fold selectivity (typically much greater) against the tested kinases. Importantly, the profile includes selectivity against other targets of relevance for angiogenesis (KDR, PDGFR, EPHB4).
T74020 O-Demethyl Lenvatinib

O-Demethyl Lenvatinib 是Lenvatinib 的代谢物。Lenvatinib (E7080) 一种具有口服活性的,多靶点酪氨酸激酶抑制剂,VEGFR1-3、FGFR1-4、PDGFR、KIT 和RET,显示有效抗癌的活性。
T74021 O-Demethyl Lenvatinib hydrochloride

O-Demethyl Lenvatinib hydrochloride 是 Lenvatinib 的代谢物。Lenvatinib (E7080) 一种具有口服活性的,多靶点酪氨酸激酶抑制剂,VEGFR1-3、FGFR1-4、PDGFR、KIT 和 RET。Lenvatinib 显示有效抗癌的活性。
T72890 VEGFR-2-IN-30

VEGFR-2-IN-30为一种针对VEGFR-2的抑制剂(IC50:66 nM),同时对PDGFR、EGFR及FGFR1亦有一定抑制作用,其IC50s分别为180、98、82 nM。此外,VEGFR-2-IN-30能够阻止癌细胞在S期的进展并诱导早期以及晚期的细胞凋亡(apoptosis)。
T79530 SA-PA

PROTACs PROTAC
SA-PA是一种细胞内自组装PROTAC,以叠氮化物和炔烃为基础。它在U87细胞中可选择性降解VEGFR-2PDGFR-β和EphB4蛋白,并可利用肿瘤组织中的内源性铜通过点击化学反应转化为PROTAC。
T63011 Henatinib

Henatinib 是一种口服具有活力的小分子多激酶抑制剂,具有广泛的抗肿瘤效果。Henatinib 能够抑制 VEGFR-2 (IC50: 0.6 nM)、c-kit (IC50: 3.3 nM)、PDGFR (IC50: 41.5 nM) 的活性。Henatinib 可以明显抑制人脐静脉内皮细胞 (HUVECs) 中的 VEGFR-2 磷酸化及其下游信号通路。
T73973 Imatinib Impurity E

Imatinib Impurity E 是 Imatinib 的杂质。Imatinib 是一种口服生物可用的酪氨酸激酶抑制剂,可选择性抑制 BCR/ABL,v-Abl,PDGFR,c-kit 激酶活性。Imatinib (STI571) 靠近 ATP 结合位点结合,将其锁定在封闭或自我抑制的构象中,因此半竞争性抑制蛋白质的酶活性。Imatinib 还抑制 SARS-CoV 和MERS-CoV。
T67442 CGP-53716

The growth factors, platelet-derived growth factor (PDGF) and basic fibroblast growth factor (bFGF) play major roles in enhanced smooth muscle cells growth in rodent blood vessels after vascular injury. Tyrosine kinase inhibition has been shown to be effective in blocking tyrosine phosphorylation at the PDGF and bFGF receptors in cultured fibroblast and vascular smooth muscle cells which in turn inhibits their proliferation[1]. CGP 53716 is a specific PDGFR tyrosine kinase inhibitor on SMC (smoo...

化合物

Regorafénib N-oxyde (M2)
Cat.No: T10157
Synonym: 瑞戈非尼杂质 13
Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Drug Metabolite
Masitinib
Cat.No: T2609
Synonym: AB1010,马赛替尼
Target: Apoptosis, FAK, c-Fms, FGFR, Bcr-Abl, PDGFR, Src, c-Kit, Hck
Ki20227
Cat.No: T4315
Synonym: N-[4-[(6,7-二甲氧基-4-喹啉基)氧基]-2-甲氧基苯基]-N'-[1-(2-噻唑基)乙基]脲
Target: c-Fms, VEGFR, CSF-1R, PDGFR, c-Kit
Tyrphostin AG1433
Cat.No: T13238
Synonym: SU1433,AG1433
Target: VEGFR, PDGFR
PP121
Cat.No: T2415
Synonym:
Target: Apoptosis, VEGFR, Bcr-Abl, PDGFR, Src, mTOR, Hck
AG 1295
Cat.No: T14137
Synonym:
Target: PDGFR
Motesanib
Cat.No: T2288
Synonym: AMG 706,莫特塞尼,莫替沙尼
Target: VEGFR, c-Kit
JI-101
Cat.No: T3476
Synonym: CGI-1842,JI 101
Target: VEGFR, PDGFR, Ephrin Receptor
JNJ-10198409
Cat.No: T15616
Synonym: 3-氟-N-(6,7-二甲氧基-2,4-二氢茚并[1,2-C〕吡唑-3-基苯基胺,JNJ-​10198409
Target: PDGFR
NVP-ADW742
Cat.No: T6079
Synonym: ADW742,ADW,GSK 552602A
Target: Apoptosis, IGF-1R
SU4312
Cat.No: T3570
Synonym: SU 4312,NSC 86429
Target: VEGFR, PDGFR
Regorafenib monohydrate
Cat.No: T1792L
Synonym:
Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Autophagy
NVP-ACC789
Cat.No: T3463
Synonym: ACC-789,ZK202650
Target: VEGFR, PDGFR
Motesanib Diphosphate
Cat.No: T2288L
Synonym: Motesanib,AMG 706,二磷酸莫替沙尼
Target: VEGFR, c-Kit
Midostaurin
Cat.No: T3211
Synonym: 米哚妥林,N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251,苯甲酰基十字孢碱
Target: Others, PKC
CHIR-124
Cat.No: T6350
Synonym: CHIR124,CHIR 124
Target: Apoptosis, GSK-3, FLT, Chk, PDGFR, Src
SIM010603
Cat.No: T71576
Synonym:
Target:
2-MT-63
Cat.No: T68484
Synonym:
Target:
O-Demethyl Lenvatinib
Cat.No: T74020
Synonym:
Target:
O-Demethyl Lenvatinib hydrochloride
Cat.No: T74021
Synonym:
Target:
VEGFR-2-IN-30
Cat.No: T72890
Synonym:
Target:
SA-PA
Cat.No: T79530
Synonym:
Target: PROTACs
Henatinib
Cat.No: T63011
Synonym:
Target:
Imatinib Impurity E
Cat.No: T73973
Synonym:
Target:
CGP-53716
Cat.No: T67442
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-01139 PDGFRA Protein, Human, Recombinant (His)

PDGFR-2,CD140A,RHEPDGFRA,platelet...

Human HEK293 Cells
PDGFRA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is P16234-1.
TMPK-00481 PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)

PDGF R beta,PDGFRB,PDGFR-2,PDGF-R...

Cynomolgus HEK293 Cells
Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β signalling, may be crucial for restoration of BBB integrity after cerebral ischemia and therefore represents a novel potential therapeutic target.
TMPK-00421 PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)

PDGFR1,CD140B,PDGFR-2,PDGF R β/CD...

Human HEK293 Cells
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa and the accession number is P09619.
TMPK-00422 PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated

PDGFR-2,PDGF R β/CD140b,PDGFR1,CD...

Human HEK293 Cells
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa and the accession number is P09619.
TMPK-01050 PDGF R beta/CD140b Protein, Canine, Recombinant (His)

JTK12,PDGF R β,PDGFR-β,PDGFR,...

Canine HEK293 Cells
PDGF R beta/CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.25 kDa and the accession number is Q6QNF3.
TMPK-00419 PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)

RHEPDGFRA,PDGFR-2,CD140A,PDGF...

Human HEK293 Cells
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The p...
TMPY-05608 PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated

platelet-derived growth factor receptor, α polypeptide,RHE

Human HEK293 Cells
PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 59.4 kDa and the accession number is P16234-1.
TMPY-00900 PDGFRA Protein, Human, Recombinant (hFc)

PDGFR-2,platelet-derived growth factor rec...

Human HEK293 Cells
PDGFRA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.9 kDa and the accession number is P16234-1.
TMPK-00943 PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)

PDGF R α/PDGFRA Protein, Cynomolgus, Recombinant (H...

Cynomolgus HEK293 Cells
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predic...
TMPK-00420 PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated

RHEPDGFRA,PDGFRA,PDGF R α/PDGFRA ...

Human HEK293 Cells
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-...
TMPY-05789 PDGFRA Protein, Mouse, Recombinant (hFc)

AI115593,platelet-derived growth factor receptor, alpha poly...

Mouse HEK293 Cells
PDGFRA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.15 kDa and the accession number is P26618-2.
TMPY-05787 PDGFRA Protein, Mouse, Recombinant (His)

CD140a,platelet-derived growth factor receptor, alpha polype...

Mouse HEK293 Cells
PDGFRA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.87 kDa and the accession number is P26618-2.
TMPY-01442 DMBT1 Protein, Human, Recombinant (His)

GP340,deleted in malignant brain tumors 1,muclin

Human HEK293 Cells
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo...
TMPJ-00850 ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)

Protein T1,suppression of tumorigenicity 2,Ly84,DER...

Mouse HEK293 Cells
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
TMPY-00891 Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)

neuropilin 1,VEGF165R,CD304,NP1,Neuropilin-1,NRP,BDCA4

Human HEK293 Cells
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2.
TMPY-02011 CD96 Protein, Human, Recombinant (His)

CD96 molecule,TACTILE

Human HEK293 Cells
CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is P40200-2.
TMPY-04113 KRAS Protein,Human,Recombinant(G12D & Q61H, His)

Kirsten rat sarcoma viral oncogene homolog,KRAS2,KI...

Human E. coli
KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-01613 Periostin/OSF-2 Protein, Mouse, Recombinant (His)

A630052E07Rik,OSF-2,Osf2,PLF,AI74...

Mouse HEK293 Cells
Periostin/OSF-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 89 kDa and the accession number is Q62009-2.
TMPY-01717 VEGF164 Protein, Mouse, Recombinant

vascular endothelial growth factor A,Vpf,Vegf,血管内皮生长因子

Mouse Baculovirus Insect Cells
VEGF164 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.4 kDa and the accession number is Q00731-2.
TMPY-02096 TACI Protein, Human, Recombinant (His)

RYZN,IGAD2,CVID,TACI,TNFRSF14B,CVID2,tumor...

Human HEK293 Cells
TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2.
TMPY-00341 FGFR3 Protein, Human, Recombinant (alpha IIIb, His)

CEK2,HSFGFR3EX,fibroblast growth factor receptor 3,...

Human HEK293 Cells
FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2.
TMPY-06056 KRAS Protein, Human, Recombinant (G12D, His)

KRAS1,K-RAS4B,Kirsten rat sarcoma viral oncogene homolog,RAL...

Human E. coli
KRAS Protein, Human, Recombinant (G12D, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P01116-2.
TMPY-00751 TrkB Protein, Human, Recombinant (His)

trk-B,GP145-TrkB/GP95-TrkB,neurotrophic tyrosine kinase, rec...

Human HEK293 Cells
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
TMPY-01691 Clusterin Protein, Human, Recombinant (CLU34, His)

SGP-2,AAG4,KUB1,CLI,CLU2,TRPM2,AP...

Human HEK293 Cells
Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.
TMPY-04844 BTN3A1 Protein, Human, Recombinant (His)

BTN3.1,butyrophilin subfamily 3 member A1,BTF5,BT3.1,CD2...

Human HEK293 Cells
BTN3A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is O00481-2.
TMPY-05288 PLGF/PGF Protein, Human, Recombinant (aa 19-149)

PLGF,PGFL,placental growth factor,D12S1900,SHGC-107...

Human E. coli
PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P49763-2.
TMPY-02820 SDF-1 Protein, Human, Recombinant (isoform a)

SDF1,chemokine (C-X-C motif) ligand 12,IRH,SCYB1

Human E. coli
SDF-1 Protein, Human, Recombinant (isoform a) is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is P48061-2.
TMPY-01935 c-Kit Protein, Human, Recombinant (His)

PBT,CD117,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncog...

Human HEK293 Cells
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P10721-2.
TMPY-04356 GSK3B Protein, Human, Recombinant (His)

glycogen synthase kinase 3 beta,glycogen synthase kinase 3 β

Human Baculovirus Insect Cells
GSK3B Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is P49841-2.
TMPY-02500 YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)

Gp39,AW208766,Brp39,chitinase 3 like 1

Mouse HEK293 Cells
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is Q61362-2.
TMPY-04396 C-ABL/ABL1 Protein, Human, Recombinant (GST)

v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...

Human Baculovirus Insect Cells
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
TMPY-01985 CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated

FCGR2,FCGR21,CD32A,FCG2,...

Human HEK293 Cells
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2.
TMPY-04644 PDGFB Protein, Human, Recombinant (His)

platelet-derived growth factor beta polypeptide,SSV,c-sis,SI...

Human P. pastoris (Yeast)
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted...
TMPY-05414 NKG2D/CD314 Protein, Mouse, Recombinant (hFc)

D6H12S2489E,NKG2-D,killer cell le...

Mouse Baculovirus Insect Cells
NKG2D/CD314 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O54709-2.
TMPY-01871 IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)

interleukin 5 receptor, alpha,IL5R,CD125,CDw12<...

Human HEK293 Cells
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q01344-2.
TMPY-02792 GDNF Protein, Human, Recombinant (HEK293)

HSCR3,ATF2,HFB1-GDNF,ATF1,glial cell derived neurot...

Human HEK293 Cells
GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.
TMPY-01888 KRAS Protein,Human, Recombinant (Q61H, His)

KRAS2,C-K-RAS,Kirsten rat sarcoma viral oncogene ho...

Human E. coli
KRAS Protein,Human, Recombinant (Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P01116-2.
TMPY-01359 ST2/IL-1 RL1 Protein, Human, Recombinant (His)

IL1RL1,IL‑1 R4,DER4,ST2,IL33R,interleukin 1 recepto...

Human HEK293 Cells
ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2.
TMPY-00747 Nectin-2 Protein, Human, Recombinant (His)

PVRR2,Nectin-2,poliovirus receptor-related...

Human HEK293 Cells
Nectin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
TMPY-05427 CD19 Protein, Human, Recombinant (hFc)

CVID3,B4,CD19 molecule

Human HEK293 Cells
CD19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is P15391-2.
TMPJ-00335 TGFBR2 Protein, Mouse, Recombinant (His)

TGFR-2,TGF-beta type II receptor,Transforming growt...

Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
TMPY-04051 c-Kit Protein, Human, Recombinant (hFc)

SCFR,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene h...

Human HEK293 Cells
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is P10721-2.
TMPY-00005 FGF-8a Protein, Human, Recombinant

fibroblast growth factor 8 (androgen-induced),FGF-8,AIGF,NEW...

Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-03425 Tau Protein, Human, Recombinant (His)

PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-as...

Human E. coli
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP...
TMPY-01199 CD74 Protein, Human, Recombinant (His)

II,DHLAG,Ia-GAMMA,CD74 molecule, major histocompatibility co...

Human HEK293 Cells
CD74 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is P04233-2.
TMPY-05586 CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated

TMIGD2,IGPR-1,transmembrane and immunoglobulin doma...

Human HEK293 Cells
The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent in mouse and rat genomes. The immunoglobulin domain of IGPR-1 was predicted to be Ig V (variable) fold and was found to be highly similar to the Ig domain of myelin-associated glycoprotein.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy. CD28H/TMIGD2 Protein, Hu...
TMPY-00849 ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)

ST2V,FIT-1,DER4,interleukin 1 receptor-like 1,T1,IL...

Human HEK293 Cells
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.72 kDa and the accession number is Q01638-2.
TMPY-02971 CLEC10A Protein, Human, Recombinant (hFc)

HML2,CD301,CLECSF13,HML,MGL,C-type lectin domain fa...

Human HEK293 Cells
CLEC10A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.6 kDa and the accession number is Q8IUN9-2.
TMPY-02432 VEGF164 Protein, Rat, Recombinant

血管内皮生长因子,vascular endothelial growth factor A

Rat Baculovirus Insect Cells
VEGF164 Protein, Rat, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.2 kDa and the accession number is P16612-2.
TMPY-02231 TrkB Protein, Mouse, Recombinant (His)

trk-B,neurotrophic tyrosine kinase, receptor, type 2

Mouse HEK293 Cells
TrkB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15209-2.
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重组蛋白

PDGFRA Protein, Human, Recombinant (His)
Cat.No: TMPY-01139
Species: Human
Expression System: HEK293 Cells
PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00481
Species: Cynomolgus
Expression System: HEK293 Cells
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00421
Species: Human
Expression System: HEK293 Cells
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00422
Species: Human
Expression System: HEK293 Cells
PDGF R beta/CD140b Protein, Canine, Recombinant (His)
Cat.No: TMPK-01050
Species: Canine
Expression System: HEK293 Cells
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00419
Species: Human
Expression System: HEK293 Cells
PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05608
Species: Human
Expression System: HEK293 Cells
PDGFRA Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00900
Species: Human
Expression System: HEK293 Cells
PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00943
Species: Cynomolgus
Expression System: HEK293 Cells
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00420
Species: Human
Expression System: HEK293 Cells
PDGFRA Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05789
Species: Mouse
Expression System: HEK293 Cells
PDGFRA Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05787
Species: Mouse
Expression System: HEK293 Cells
DMBT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01442
Species: Human
Expression System: HEK293 Cells
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
Cat.No: TMPJ-00850
Species: Mouse
Expression System: HEK293 Cells
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)
Cat.No: TMPY-00891
Species: Human
Expression System: HEK293 Cells
CD96 Protein, Human, Recombinant (His)
Cat.No: TMPY-02011
Species: Human
Expression System: HEK293 Cells
KRAS Protein,Human,Recombinant(G12D & Q61H, His)
Cat.No: TMPY-04113
Species: Human
Expression System: E. coli
Periostin/OSF-2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01613
Species: Mouse
Expression System: HEK293 Cells
VEGF164 Protein, Mouse, Recombinant
Cat.No: TMPY-01717
Species: Mouse
Expression System: Baculovirus Insect Cells
TACI Protein, Human, Recombinant (His)
Cat.No: TMPY-02096
Species: Human
Expression System: HEK293 Cells
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
Cat.No: TMPY-00341
Species: Human
Expression System: HEK293 Cells
KRAS Protein, Human, Recombinant (G12D, His)
Cat.No: TMPY-06056
Species: Human
Expression System: E. coli
TrkB Protein, Human, Recombinant (His)
Cat.No: TMPY-00751
Species: Human
Expression System: HEK293 Cells
Clusterin Protein, Human, Recombinant (CLU34, His)
Cat.No: TMPY-01691
Species: Human
Expression System: HEK293 Cells
BTN3A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04844
Species: Human
Expression System: HEK293 Cells
PLGF/PGF Protein, Human, Recombinant (aa 19-149)
Cat.No: TMPY-05288
Species: Human
Expression System: E. coli
SDF-1 Protein, Human, Recombinant (isoform a)
Cat.No: TMPY-02820
Species: Human
Expression System: E. coli
c-Kit Protein, Human, Recombinant (His)
Cat.No: TMPY-01935
Species: Human
Expression System: HEK293 Cells
GSK3B Protein, Human, Recombinant (His)
Cat.No: TMPY-04356
Species: Human
Expression System: Baculovirus Insect Cells
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02500
Species: Mouse
Expression System: HEK293 Cells
C-ABL/ABL1 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04396
Species: Human
Expression System: Baculovirus Insect Cells
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-01985
Species: Human
Expression System: HEK293 Cells
PDGFB Protein, Human, Recombinant (His)
Cat.No: TMPY-04644
Species: Human
Expression System: P. pastoris (Yeast)
NKG2D/CD314 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05414
Species: Mouse
Expression System: Baculovirus Insect Cells
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)
Cat.No: TMPY-01871
Species: Human
Expression System: HEK293 Cells
GDNF Protein, Human, Recombinant (HEK293)
Cat.No: TMPY-02792
Species: Human
Expression System: HEK293 Cells
KRAS Protein,Human, Recombinant (Q61H, His)
Cat.No: TMPY-01888
Species: Human
Expression System: E. coli
ST2/IL-1 RL1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01359
Species: Human
Expression System: HEK293 Cells
Nectin-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-00747
Species: Human
Expression System: HEK293 Cells
CD19 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05427
Species: Human
Expression System: HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00335
Species: Mouse
Expression System: HEK293 Cells
c-Kit Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04051
Species: Human
Expression System: HEK293 Cells
FGF-8a Protein, Human, Recombinant
Cat.No: TMPY-00005
Species: Human
Expression System: E. coli
Tau Protein, Human, Recombinant (His)
Cat.No: TMPY-03425
Species: Human
Expression System: E. coli
CD74 Protein, Human, Recombinant (His)
Cat.No: TMPY-01199
Species: Human
Expression System: HEK293 Cells
CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05586
Species: Human
Expression System: HEK293 Cells
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00849
Species: Human
Expression System: HEK293 Cells
CLEC10A Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02971
Species: Human
Expression System: HEK293 Cells
VEGF164 Protein, Rat, Recombinant
Cat.No: TMPY-02432
Species: Rat
Expression System: Baculovirus Insect Cells
TrkB Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02231
Species: Mouse
Expression System: HEK293 Cells
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