76
38
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143
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0120B |
Flag Tag Immunomagnetic Beads
Flag Tag 免疫沉淀磁珠 |
||
C0120 |
Flag Tag Immunoprecipitation Kit
Flag Tag 免疫沉淀试剂盒 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T78332 |
Eftilagimod alfa
IMP321,LAG-3Ig |
||
Eftilagimod alfa为重组LAG-3Ig融合蛋白,具有MHC II 类分子结合能力。该药物通过介导抗原提呈细胞(APC)的激活进而激活CD8 T细胞,可用于研究转移性黑色素瘤及转移性乳腺癌。 | |||
T78266 |
Anti-Mouse LAG-3 Antibody (C9B7W)
|
||
Anti-MouseLAG-3Antibody为针对小鼠LAG-3的Rat源IgG1抗体抑制剂。 | |||
T78247 |
Ieramilimab
IMP701,LAG525 |
||
Ieramilimab(LAG525;IMP701)是一款针对LAG-3的人源化IgG4单克隆抗体,它通过结合到LAG-3来阻断其与MHC-II 分子的相互作用。 | |||
TP1274 |
3X FLAG peptide
|
||
The 3X FLAG Peptide is a synthetic peptide of 23 amino acid residue. The Asp-Tyr-Lys-Xaa-Xaa-Asp motif is repeated three times in the peptide. | |||
T6797 |
Telaglenastat
CB 839,CB839,CB-839 |
transporter; Glutaminase; Autophagy | Autophagy; Metabolism; Proteases/Proteasome |
Telaglenastat (CB 839) 是一种选择性可逆的,有口服活性的谷氨酰胺酶 1 (GLS1) 抑制剂,抑制 GLS1剪接变异体 KGA 和 GAC,比 GLS2 具有更高的选择性。它可诱导细胞自噬 ,具有抗肿瘤活性。它对小鼠类肾和脑中的内源性谷氨酰胺酶的 IC50值分别为 23 nM 和 28 nM。 | |||
T5031 |
Elagolix sodium
NBI-56418 sodium,恶拉戈利钠 |
GNRH Receptor | GPCR/G Protein |
Elagolix sodium (NBI-56418 sodium) 是人GnRH 受体拮抗剂,其IC50=0.25 nM,Ki=3.7 nM。 | |||
T17265 |
Ximelagatran
EXANTA,H 376-95,H37695,希美加群,H 376/95,H-37695,H 37695 |
Thrombin | Proteases/Proteasome |
Ximelagatran (H 376-95) 是一种口服活性凝血酶抑制剂,可选择性的、竞争性的抑制游离和凝块结合的凝血酶。它是一种抗凝药物,具有快速起效的抗凝作用,可预测的,剂量依赖性的药代动力学和药效学。 | |||
TP1275 |
3X FLAG peptide TFA (402750-12-3 free base)
3X FLAG peptide TFA |
Others | Others |
3X FLAG peptide TFA (402750-12-3 free base) (3X FLAG peptide TFA) 是一种含有 23 个氨基酸残基的合成肽。 Asp-Tyr-Lys-Xaa-Xaa-Asp 基序在肽中重复了 3 次。 | |||
T11994 |
Melagatran
|
Thrombin | Proteases/Proteasome |
Melagatran 是一种直接作用且可口服的凝血酶抑制剂。Melagatran 专一性抑制凝血酶,但不影响凝血级联中的其他酶或纤溶酶。Melagatran不依赖内源性辅因子发挥其抗凝血酶效果,可缓解内毒素血症的有害影响。因此,Melagatran作为预防动脉闭塞的策略显示出前景。 | |||
T15704 |
Lagociclovir
MIV-210 |
HBV | Microbiology/Virology |
Lagociclovir (MIV-210) 是一种核苷类似物,是一种可用治疗 HBV82的抗病毒化合物,可抑制野生型乙型肝炎病毒 (HBV) 在永久表达 HBV 的人肝癌细胞系中的复制。 | |||
T3104L |
(1S,2R)-Globalagliatin
(1S,2R)-Globalagliatin(1S,2R-1234703-40-2) |
Glucokinase | Metabolism |
(1S,2R)-Globalagliatin 是一种高效的葡萄糖激酶 (GK) 激活剂,可用于研究 2 型糖尿病。 | |||
T7143 |
Alagebrium chloride
4,5-二甲基-3-(2-氧代-2-苯基乙基)噻唑氯化物,ALT711,阿拉氯胺 |
Others; Endogenous Metabolite | Metabolism; Others |
Alagebrium chloride (ALT711) 是晚期糖基化终产物(AGE) 抑制剂。 | |||
T11174 |
(R)-Elagolix
恶拉戈利,NBI-56418 |
GNRH Receptor | GPCR/G Protein |
(R)-Elagolix (NBI-56418) 是口服具有活性的、选择性高的非肽类促性腺激素释放激素受体短期有效拮抗剂 (KD = 54 pM)。 | |||
T3104 |
Globalagliatin
LY2608204 |
Glucokinase | Metabolism |
Globalagliatin (LY2608204) 是一种葡萄糖激酶 (GK) 活化剂,EC50=42 nM。 | |||
T25310 |
Dersimelagon
MT-7117 |
Melanocortin Receptor | GPCR/G Protein; Neuroscience |
Dersimelagon (MT-7117) (MT-7117) 是一种具有口服活性的选择性黑皮质素 1 受体(MC1R) 激动剂,对人 (h)、食蟹猴 (cm)、小鼠 (m) 和大鼠 (r) MC1R 的 EC50 值分别为 8.16、3.91、1.14 和 0.251 nM。Dersimelagon 对 hMC1R 和 hMC4R 表现出良好的亲和力,Ki 值分别为 2.26 和 32.9 nM。Dersimelagon 可用于皮肤色素沉着的研究。 | |||
T2296 |
Trelagliptin succinate
曲格列汀琥珀酸盐,琥珀酸曲格列汀,SYR-472 succinate,SYR472 |
Proteasome; DPP-4 | Proteases/Proteasome; Ubiquitination |
Trelagliptin succinate (SYR-472 succinate) 是一种有效的,具有口服活性的DPP-4抑制剂,IC50=4 nM。它可以改善体内血糖控制,能够用于2 型糖尿病(T2DM) 的研究。 | |||
TP1170L |
Flagelin 22 acetate
Flagelin 22 acetate(304642-91-9 free base) |
Others | Others |
Flagelin 22 acetate 是细菌鞭毛蛋白的一部分,是在植物和藻类中一种有效的诱导剂。 | |||
TP1273 |
FLAG peptide
|
Others | Others |
FLAG peptide 是一种由八个氨基酸组成的多肽 (Asp-Ty-rLys-Asp-Asp-Asp-Asp-Lys),具有肠激酶切割位点,可用于抗体介导的重组蛋白的识别和纯化。 | |||
T6237 |
Trelagliptin
SYR-472,曲格列汀 |
Proteasome; DPP-4 | Proteases/Proteasome; Ubiquitination |
Trelagliptin (SYR-472) 是一种有效的,具有口服活性的DPP-4抑制剂,IC50=4 nM。它可以改善体内血糖控制,能够用于2 型糖尿病 (T2DM) 的研究。 | |||
T10861 |
Collagen proline hydroxylase inhibitor-1
|
Others | Others |
Collagen proline hydroxylase inhibitor-1 具有抗纤维增生活性。 | |||
T126127 | Calendulaglycoside B | ||
Calendulaglycoside B 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126127,CAS号为 126577-19-3。 | |||
T30754 |
Cartilaginomarginadin
Yama-Ninjin 1 |
||
Cartilaginomarginadin is a biochemical. | |||
T63404 | Xelaglifam | ||
Xelaglifam 是 G 蛋白偶联受体 40 (GPR40) 的有效激动剂,表现出降血糖作用。 | |||
TQ0272 |
Balaglitazone
DRF 2593,巴格列酮,NN 2344 |
PPAR | DNA Damage/DNA Repair; Metabolism |
Balaglitazone is a selective partial agonist for PPARγ (EC50: 1.351 μM for human PPARγ). | |||
T76876 | Volagidemab | ||
Volagidemab,一种针对胰高血糖素受体(GCGR)的拮抗性单克隆抗体(mAb),主要应用于1型糖尿病(T1D)的研究。 | |||
T82394 |
FLAG-Cys
|
||
FLAG-Cys为带有Cys残基的FLAG肽,具有免疫原性。 | |||
TP2190 |
vitamin D binding protein precrusor (208-218) [Homo sapiens]/[Oryctolagus cuniculus]
|
Others | Others |
Vitamin D-binding protein is a multifunctional, highly expressed, polymorphic serum protein. These range from the transport of vitamin D metabolites to possible roles in the immune system and host defense. The molecular weight range, the time course of ap | |||
T75718 |
Dulaglutide
|
||
Dulaglutide (LY2189265),一种GLP-1受体激动剂,用于2型糖尿病的研究。 | |||
T72143 |
Velagliflozin proline hydrate
|
||
Velagliflozin proline hydrate 是 Velagliflozin 的临床形式。Velagliflozin 是一种可口服的钠-葡萄糖协同转运蛋白 2 (SGLT2) 抑制剂,具有抗糖尿病的活性。 特别是,Velagliflozin 减少肾葡萄糖重吸收,促进葡萄糖尿,从而降低血糖和胰岛素浓度。 | |||
T124735 |
3-Methyl ellagic acid
|
||
3-Methyl ellagic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124735。 | |||
T23906 |
Collagenase inhibitor CI-2
SC 40827 |
||
SC 40827 is a Collagenase inhibitor CI-2. | |||
T17221 |
Velagliflozin
|
SGLT | GPCR/G Protein |
Velagliflozin is an orally available inhibitor of sodium-glucose cotransporter 2. | |||
T10862 |
Collagen proline hydroxylase inhibitor
|
Others | Others |
Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents. | |||
T25928 |
Pelagiomicin A
Antibiotic 2088A,LL-14I352-alpha,Pelagiomicin-A |
||
Pelagiomicin A is used as an anticancer antibiotic produced by the marine bacterium Pelagiobacter variabilis. | |||
T60655 | Resomelagon | ||
Resomelagon (AP1189) 是具有口服活性的有效黑素皮质素受体 (MR) 激动剂,可诱导Ca2+流动和 ERK1/2 磷酸化。Resomelagon 显示出抗炎活性, 可用于研究肥胖和慢性炎症。 | |||
T79090 |
Bivamelagon
MC-4R Agonist 2 |
Melanocortin Receptor | GPCR/G Protein; Neuroscience |
MC-4R Agonist 2 (实施例 1)作为MC4R激动剂,适用于肥胖、糖尿病、炎症及勃起功能障碍的研究领域。 | |||
TP2301 |
type II collagen fragment
|
Others | Others |
Type II collagen is composed of a triple helix of three identical α chains. These molecules associate to form a fibril that is stabilized by intermolecular crosslinks1. Damage to the fibrillar meshwork, made up of primarily type II collagen (z 90–95%), ma | |||
T25601 |
Lagunamycin
|
||
Lagunamycin is used as a novel 5-lipoxygenase inhibitor. | |||
T60611 |
Talaglumetad hydrochloride
|
||
Talaglumetad (hydrochloride) 是Eglumegad 的前药,Eglumegad 是II 型代谢型谷氨酸受体(mGluR2/3)有效选择性的激动剂,用于治疗焦虑等精神疾病。 | |||
T69456 | Melagatran monohydrate | ||
Melagatran monohydrate is a thrombin inhibitor. Melagatran prevents tissue factor expression in human platelet-monocyte heterotypic complexes. Melagatran reduces advanced atherosclerotic lesion size and may promote plaque stability in apolipoprotein E-deficient mice. | |||
T72324 | Lagociclovir valactate | ||
Lagociclovir valactate 是 Lagociclovir 的前药。Lagociclovir valactate 是一种具有口服活性的抗HBV 试剂。 | |||
T39309 |
Telaglenastat hydrochloride
CB-839 hydrochloride |
||
Telaglenastat (CB-839) hydrochloride is a first-in-class, reversible, and orally active inhibitor of glutaminase 1 (GLS1). It selectively inhibits the splice variants of GLS1, specifically KGA (kidney-type glutaminase) and GAC (glutaminase C), as compared to GLS2. Telaglenastat hydrochloride has an IC50 of 23 nM for endogenous glutaminase in mouse kidney and 28 nM in the brain. In addition, it induces autophagy and exhibits antitumor activity. | |||
TP1170 |
Flagelin 22
Flagellin 22 |
||
Flagelin 22, a bacterial flagellin fragment, serves as a potent elicitor for plants and algae. | |||
TP1169 |
Flagelin 22 TFA (304642-91-9 free base)
Flagellin 22 TFA,Flagelin 22 TFA |
||
Flagelin 22 TFA (Flagellin 22 TFA), a fragment of bacterial flagellin, is an effective elicitor in both plants and algae. | |||
TP1643 |
Alpha 1(I) Collagen (614-639), human
|
||
This is a peptide inhibitor of collagen fibrillar matrix assembly. | |||
TP2343 |
Lagatide
|
||
Lagatide is a synthetic heptapeptide that has antisecretory activity. | |||
T125016 |
4,4'-Di-O-methylellagic acid
|
||
4,4'-Di-O-methylellagic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125016,CAS号为 3374-77-4。 | |||
T124973 |
3-O-Methylellagic acid 3'-O-alpha-rhamnopyranoside
|
||
3-O-Methylellagic acid 3'-O-alpha-rhamnopyranoside 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124973。 | |||
T34641 |
Silagaba161
Silagaba-161,Silagaba 161 |
||
Silagaba161 is a silicon-containing GABA derivative which treats neuropathic pain without central nervous system related side effects. | |||
T69607 | Dersimelagon phosphate | ||
Dersimelagon phosphate is a selective melanocortin-1 receptor (MC1R) agonist that increases skin melanin without sun exposure and is being developed to increase light tolerance in EPP/XLP patients. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6S1027 |
Tussilagone
|
Others | Others |
Tussilagone 是Tussilago farfara 的主要活性成分,具有抗炎作用。它抑制盲肠结扎和穿刺导致脓毒症的小鼠的炎症反应,提高其生存率。它改善葡聚糖硫酸钠诱导的小鼠结肠炎的炎症反应。 | |||
T9328 |
Ellagic Acid Dihydrate
|
P450 | Metabolism |
Ellagic Acid Dihydrate 抑制 CYP1A1 依赖的benzo[a]pyrene 活化。 | |||
T3921 |
Punicalagin
安石榴甙,安石榴苷 |
SARS-CoV; HBV | Microbiology/Virology |
Punicalagin 是一种在石榴中发现的主要鞣花单宁,是可逆且非竞争性的3CLpro 抑制剂,有抗氧化、抗炎和抗癌作用。它有潜力研究 COVID-19 。 | |||
TQ0180 |
Chebulagic acid
|
SARS-CoV; Influenza Virus; Lipoxygenase; COX | Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience |
Chebulagic acid 是从 Terminalia chebula Retz 中分离出来的一种 COX-LOX 双重抑制剂,有抗炎和抗感染作用。它抑制 SARS-CoV-2病毒的复制,EC50值为 9.76 μM。它还是 M2(S31N)抑制剂和抗流感病毒剂。 | |||
T64812 |
Collagenase Type I
Collagenase I,Collagenase Type I (From microorganisms) |
Others | Others |
Collagenase Type I 是一种蛋白水解酶,能分解胶原蛋白中的肽键(胶原蛋白是结缔组织的主要结构蛋白)。Collagenase 已被探索作为一种潜在的治疗选择来分解突出的椎间盘物质,从而减少对附近神经的压迫。Collagenase 可能有助于过度疤痕组织的分解和重组,潜在地改善组织功能和外观。Collagenase 具有治疗椎间盘突出、瘢痕疙瘩、脂肪团、脂肪瘤以及佩罗尼氏病和手掌纤维瘤病等方面的潜力。 | |||
T3795 |
Corilagin
|
Apoptosis; TLR; Reverse Transcriptase; Antibacterial; Autophagy | Apoptosis; Autophagy; Immunology/Inflammation; Microbiology/Virology |
Corilagin 是一种鞣酸,有抑制 RNA 肿瘤病毒逆转录酶的活性。它抑制金黄色葡萄球菌的生长,MIC 为 25 μg/mL。它有抗肿瘤活性,可用于肝癌和卵巢癌。 | |||
T4954 |
SMILAGENIN ACETATE
Nsc15488,乙酰知母皂苷元 |
Others | Others |
Smilagenin acetate 是 sapogenin 衍生物,在细胞实验中能上调乙酰胆碱 m2 受体的表达,可用于痴呆的研究。 | |||
T0465 |
Ellagic acid
鞣花酸,Gallogen,Elagostasine |
Hedgehog/Smoothened; Casein Kinase; Reactive Oxygen Species; Topoisomerase; Endogenous Metabolite; PKA; Syk; PKC; Carbonic Anhydrase | Angiogenesis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors |
Ellagic acid (Gallogen) 是从 Eucalyptus maculata Hook 和 E. Hemipholia F. Muell 的 kino 中分离出来的稠合四环天然产物,是一种有效的,ATP 竞争性的CK2抑制剂,IC50和Ki 值分别为 40 nM 和 20 nM。 | |||
TN7213 |
Ellagic acid 3-O-α-L-rhamnopyranoside
|
Others | Others |
Ellagic acid 3-O-α-L-rhamnopyranoside 是一种天然产物,存在于植物鹅绒委陵菜Potentilla anserina 的块根中。 | |||
T75674 | Pedunculagin | ||
Pedunculagin为有效的1型5α-还原酶抑制剂,能抑制一氧化氮(NO)、IL-6、IL-8产生,并降低5α-reductase蛋白质表达,具抗炎活性。 | |||
TN6308 |
Karavilagenin B
3β,25-Dihydroxy-7β-methoxycucurbita-5,23-diene |
||
Karavilagenin B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6308,CAS号为 912329-02-3。 | |||
TN6494 |
3-O-methylellagic acid 4'-O-alpha-L-rhamnopyranoside
|
||
3-O-methylellagic acid 4'-O-alpha-L-rhamnopyranoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6494,CAS号为 51768-39-9。 | |||
TN1615 |
Epitheaflagallin 3-O-gallate
表没食子儿茶素没食子酸酯 |
MMP | Proteases/Proteasome |
Epitheaflagallin 3-O-gallate is a promising functional food material with potential antiobesity and antiperiodontal disease activities, it suppresses tumor growth through the suppression of angiogenesis. | |||
TN6240 |
Demethylagrimonolide 6-O-glucoside
Desmethylagrimonolide 6-O-β-D-glucopyranoside |
||
Demethylagrimonolide 6-O-glucoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6240,CAS号为 1257408-55-1。 | |||
T75665 | 3-O-Methylellagic acid | ||
3-O-Methylellagic acid 是一种天然产物,从Myrciaria cauliflora 中分离得到,具有抗炎活性。3-O-Methylellagic acid 对葡萄糖转运有抑制作用。3-O-Methylellagic acid 具有抗菌活性,对葡萄球菌 ATCC 25923 菌株作用的 MIC 值为 32 μg/mL。 | |||
TN1978 |
Neochebulagic acid
新诃黎勒酸 |
Others | Others |
Neochebulagic acid is a natural product | |||
T81402 |
Primulagenin A
|
||
Primulagenin A,一种苷类化合物,可从刺五加(Eleutheroccus senticosus)根中提取。 | |||
T4954L |
Smilagenin
PYM50028,Cogane,AI3-44895,PYM 50028 |
||
Smilagenin is an orally active inducer of nonpeptide neurotrophic factor. It also prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons, and by MPTP in a mouse model of Parkinson's disease. | |||
TN1242 |
3,3'-Di-O-methylellagic acid
3,8-Di-O-methylellagic acid,3,3'-O-二甲基鞣花酸 |
Others; TNF; Antifection | Apoptosis; Microbiology/Virology; Others |
3,3'-Di-O-methylellagic acid reveals moderate antibacterial activity, it also shows strong DPPH radical scavenging activities with SC50 of 123.3 ug/mL. It has a lower capacity of stimulating murine peritoneal macrophages to release nitric oxide and tumoural-alpha necrose factor | |||
TN6156 |
3,4,3'-Tri-O-methylflavellagic acid
|
||
3,4,3'-Tri-O-methylflavellagic acid 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6156,CAS号为 13756-49-5。 | |||
TN6226 | 3-O-Methylellagic acid 4-O-rhamnoside | ||
3-O-Methylellagic acid 4-O-rhamnoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6226,CAS号为 639089-97-7。 | |||
TN1234 |
3,3'-Di-O-methylellagic acid-4'-O-β-D-glucopyranoside
3,3'-Di-O-methylellagic acid 4'-glucoside,3,3'-二-O-甲基柔花酸-4'-O-BETA-D-吡喃葡萄糖苷 |
Others | Others |
3,3'-Di-O-methylellagic acid 4'-glucoside is a natural product | |||
TN6255 |
3,7,8-Tri-O-methylellagic acid 2-O-rutinoside
3,3',4'-Tri-O-methylellagic acid 4-O-rutinoside |
||
3,7,8-Tri-O-methylellagic acid 2-O-rutinoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6255,CAS号为 56470-18-9。 | |||
TN5945 |
Karavilagenin A
3β-Hydroxy-7β,25-dimethoxycucurbita-5,23-diene |
||
Karavilagenin A是一种天然产物,属于葫芦科苦瓜属,其产品编号为 TN5945,CAS号为 912329-03-4。Karavilagenin A可用作对照参考。 | |||
TN4380 | Karavilagenin D | Others | Others |
Karavilagenin D exhibits inhibitory effects on skin-tumor promotion in an in vivo two-stage mouse skin carcinogenesis test based on 7,12-dimethylbenz[a]anthracene (DMBA) as initiator, and with TPA as a promoter. It exhibits inhibition effect against human | |||
T83381 |
2'-Hydroxylagarotetrol
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'2'-Hydroxylagarotetrol为苯醚色酮衍生物。 | |||
T82478 |
Ellagic acid 4-O-α-L-arabinopyranoside
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Ellagic acid 4-O-α-L-arabinopyranoside,一种具有抗氧化活性的化合物,从Dimocarpus longan Lour, syn. Euphoria longan Lam.(龙眼)中分离得到。 | |||
TN6288 |
Karavilagenin F
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Karavilagenin F 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6288,CAS号为 1639024-15-9。 | |||
TN1203 |
2,3,8-Tri-O-methylellagic acid
2,3,8-三邻甲基鞣花酸 |
Antifection | Microbiology/Virology |
2,3,8-tri-O-Methyl ellagic acid has antimicrobial activity agaist Vibro cholera, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacillus cereus, Escherichia coli. | |||
TN6315 |
25-O-Methylkaravilagenin D
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25-O-Methylkaravilagenin D 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6315,CAS号为 1363422-85-8。 | |||
TN6312 | Solagenin 6-O-β-D-quinovopyranoside | ||
Solagenin 6-O-β-D-quinovopyranoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6312,CAS号为 184686-03-1。 | |||
TN6516 |
Selaginellin F
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Selaginellin F is a natural product from Selaginella pulvinata. | |||
TN6515 |
Selaginellin
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Selaginellin has a neuroprotective effect against L-glutamate-induced neurotoxicity through mechanisms related to anti-oxidation and anti-apoptosis via scavenging reactive oxygen species and up-regulating the expression of klotho gene. Selaginellin shows | |||
T8305 |
Ellagic acid (hydrate)
Ellagic Acid hydrate,鞣花酸水合物 |
Antioxidant; Casein Kinase | Metabolism; oxidation-reduction; Stem Cells |
Ellagic acid (hydrate) 是存在于许多水果和蔬菜中的一种天然抗氧化剂,是 ATP 竞争性的 CK2抑制剂,IC50和 Ki 值分别为 40 nM 和 20 nM。 | |||
T81955 |
Lagunamine
19-Hydroxytubotaiwine |
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Lagunamine (19-Hydroxytubotaiwine) 为源自菲律宾Alstonia scholaris叶的生物碱。 | |||
T75546 | Ellagic acid 4-O-β-D-xylopyranoside | ||
Ellagic acid 4-O-β-D-xylopyranoside,天然鞣花单宁,展现抗菌活性。同时,作为黄嘌呤氧化酶 (xanthine oxidase) 抑制剂,其50为 2.1 μg/mL。 | |||
TN5313 |
Convallagenin B
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Convallagenin B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5313,CAS号为 17934-59-7。 | |||
TN2482 |
1,2,3-Tri-O-methyl-7,8-methyleneflavellagic acid
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Others | Others |
1,2,3-Tri-O-methyl-7,8-methyleneflavellagic acid 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2482,CAS号为 69251-99-6。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04730 |
LAG-3 Protein, Human, Recombinant (His)
LAG-3,lymphocyte-activation gene 3,CD223 |
Human | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPY-04939 |
LAG-3 Protein, Human, Recombinant
LAG-3,lymphocyte-activation gene 3,CD223 |
Human | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPY-04731 |
LAG-3 Protein, Human, Recombinant (mFc)
lymphocyte-activation gene 3,CD223,LAG-3 |
Human | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPY-05746 |
LAG-3 Protein, Mouse, Recombinant
lymphocyte-activation gene 3,LAG-3,Ly66,CD223 |
Mouse | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPY-04528 |
LAG-3 Protein, Human, Recombinant (hFc)
lymphocyte-activation gene 3,CD223,LAG-3 |
Human | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPY-04612 |
LAG-3 Protein, Mouse, Recombinant (His)
LAG-3,Ly66,lymphocyte-activation gene 3,CD223 |
Mouse | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPY-05130 |
LAG-3 Protein, Human, Recombinant, Biotinylated
lymphocyte-activation gene 3,CD223,LAG-3 |
Human | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPY-06931 |
LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated
lymphocyte-activation gene 3,CD223,LAG-3 |
Human | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPY-04611 |
LAG-3 Protein, Mouse, Recombinant (hFc)
lymphocyte-activation gene 3,Ly66,LAG-3,CD223 |
Mouse | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPJ-01421 |
LAG-3 Protein, Cynomolgus, Recombinant (hFc)
LAG-3,Protein FDC,Lymphocyte activation gene 3 prot... |
Cynomolgus | Human Cells |
Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. LAG3 is involved in lymphocyte activation and can bind to HLA class-II antigens. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells and acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells throug... | |||
TMPJ-00321 |
LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated
Lymphocyte activation gene 3 protein,CD223,LAG-3,Pr... |
Human | Human Cells |
Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. LAG3 is involved in lymphocyte activation and can bind to HLA class-II antigens. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells and acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells throug... | |||
TMPY-05092 |
LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His)
lymphocyte-activation gene 3 |
Cynomolgus | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPY-06547 |
Granulysin Protein, Human, Recombinant (hFc)
NKG5,LAG-2,TLA519,LAG2,granulysin,D2S69E |
Human | HEK293 |
Granulysin Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 41.12 kDa. Accession number: P22749-1 | |||
TMPY-03047 |
Stathmin 1 Protein, Human, Recombinant (His)
SMN,OP18,stathmin 1,LAP18,C1orf215,PP17,Lag,PP19,PR... |
Human | E. coli |
Stathmin1 (STMN1) is a cytosolic phosphoprotein that regulates cellular microtubule dynamics and is known to have oncogenic activity. STMN1 is a possible biomarker for paclitaxel sensitivity and poor prognosis in GC and could be a novel therapeutic target in metastatic GC. STMN1 expression might serve as a biomarker for determining patient atypical meningioma prognosis. Stathmin1 (STMN1) is a cytosolic protein involved in microtubule dynamics through inhibition of tubulin polymerization and prom... | |||
TMPY-03759 |
LAG-3 Protein, Rat, Recombinant (His)
lymphocyte-activation gene 3 |
Rat | HEK293 |
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... | |||
TMPY-00646 |
CCL4 Protein, Human, Recombinant (His)
SCYA2,G-26,MIP-1-β,LAG-1,MIP1B,AT744.1,SCYA4,MIP-1-... |
Human | Yeast |
CCL4 (C-C chemokine ligand 4), is a macrophage inflammatory protein with a chief effect in inflammation and immune-regulation, and was documented in cancer progression by promoting instability in the tumor environment. The inflammatory chemokine (C-C motif) ligand 4 (CCL4) plays an important role in the pathogenesis and progression of cancer. In particular, higher serum CCL4 levels in patients with oral squamous cell carcinoma (OSCC) are associated with a more advanced stage of disease. CCL4 may... | |||
TMPY-05057 |
Complement C5 Protein, Human, Recombinant (His & FLAG)
C5b,ECLZB,C5a,CPAMD4,C5D,complement component 5,Complement C... |
Human | HEK293 |
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathways of complement activation. The structure of C5a includes a core region consisting of four, anti-parallel alpha-helices held together by three disulfide linkages and a structured C-terminal tail, and C5a is rapidly metabolised by carboxypeptidase B to a 73 amino acid low activity... | |||
TMPY-05374 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His), Biotinylated
T3D,CD3d molecule, δ (CD3-TCR complex),CD3d molecule, delta ... |
Human | HEK293 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His), Biotinylated is expressed in HEK293 cells. | |||
TMPY-04010 |
CD3E & CD3G Heterodimer Protein, Human, Recombinant (Fc-Flag & mFc)
T3E,TCRE,CD3e molecule, epsilon (CD3-TCR complex),IMD18,CD3E... |
Human | HEK293 |
CD3E & CD3G Heterodimer Protein, Human, Recombinant (Fc-Flag & mFc) is expressed in HEK293 with Fc-Flag tag and mFc tag. The predicted molecular weight is 76.9 kDa. Accession number: NP_000724.1&NP_000064.1 | |||
TMPY-03878 |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone... |
Human | HEK293 |
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of ITGAV&ITGB6 via clathrin-med... | |||
TMPY-04290 |
S100A8 & S100A9 Heterodimer Protein, Human, Recombinant (Flag & His)
S1A8,CAGA,CFAG,CAGB,MRP8 & S1A9,MRP14 |
Human | Baculovirus-Insect Cells |
S100A8 & S100A9 Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in Baculovirus-Insect Cells with Flag and His tag. The predicted molecular weight is 12.2 kDa. Accession number: NP_002955.2&NP_002956.1 | |||
TMPY-04793 |
IL-35 Protein, Human, Recombinant (Flag & His)
NKSF1,P35,白介素,Interleukin-35,CLMF,白细胞介素,NFSK,IL-12A,IL-35,in... |
Human | HEK293 |
IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. IL12A, together with IL27B, form a disulfide-linked heterodimer: IL12A&IL27B. IL12A&IL27B is required for the T-cell-independent induction of IFN-gamma and is important for the differentiation of both Th1 and T... | |||
TMPK-00176 |
BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag)
BLyS,TALL-1,TNFSF13B,DTL,TNFSF20,TALL-1δ BAFF,TALL-1delta BA... |
Human | HEK293 |
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. | |||
TMPY-05669 |
CD8A & CD8B Heterodimer Protein, Human, Recombinant (Flag & His)
|
Human | HEK293 |
CD8A & CD8B Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 cells. | |||
TMPY-05302 |
CD79 Protein, Human, Recombinant (Flag & His)
MB-1,IGA,CD79a molecule, immunoglobulin-associated α,CD79a m... |
Human | HEK293 |
CD79 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 37.5 kDa. Accession number: NP_001774.1&NP_000617.1 | |||
TMPJ-00137 |
APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)
TRDL-1,TNF- and APOL-related leukocyte expressed ligand 2,Tu... |
Human | Human Cells |
APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. Secreted human APRIL, which consists almost entirely of a single TNF homology domain, shares 85% amino acid sequence identity with mouse and rat APRIL. Both APRIL and its close relative BAFF bind and signal through the TNF superfamily recept... | |||
TMPY-04643 |
Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His)
integrin, α5 (fibronectin receptor, α polypeptide),integrin,... |
Mouse | HEK293 |
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of ITGAV&ITGB6 via clathrin-med... | |||
TMPY-03745 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
CD3-DELTA,CD3d molecule, delta (CD3-TCR complex),CD3d molecu... |
Human | HEK293 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 31.05 kDa. Accession number: P04234-1&P07766-1 | |||
TMPY-02159 |
Integrin alpha 5 beta 1 Protein, Human, Recombinant (Flag & His)
Integrin alpha 5 β1,Integrin α5 β 1,integrin, α5 (fibronecti... |
Human | HEK293 |
Integrin alpha 5 beta 1 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 192 kDa. Accession number: P08648&P05556-1 | |||
TMPK-01208 |
DLL3 Protein, Human, Recombinant (His & Flag)
Pudgy,SCDO1,DLL3,Delta3,SCDO1δ3,δ3,SCDO1delta3 |
Human | HEK293 |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). | |||
TMPY-01860 |
Collagen II/COL2A1 Protein, Human, Recombinant (aa 1242-1487, His)
SEDC,collagen, type II, alpha 1,COL11A3,AOM,STL1,co... |
Human | HEK293 |
COL2A1 is the alpha-1 chain of type II collagen which is a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this protein are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of th... | |||
TMPJ-00066 |
BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag)
Tumor necrosis factor receptor superfamily member 17,Tnfrsf1... |
Human | Human Cells |
B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. Mouse BCMA is a 185 amino acid (aa) protein consisting of a 49 aa extracellular domain, a 23 aa transmembrane domain, and a 113 aa intracellular domain. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. Within the TNFRSF, it shares the highest homology with TACI. BCMA and TACI have both been shown to bind to APRIL and BAFF, members of the TNF ligand ... | |||
TMPJ-00185 |
CD20 Protein, Human, Recombinant (His & Flag)
CD20,Membrane-spanning 4-domains subfamily A member 1,B-lymp... |
Human | Human Cells |
CD20 is a 33-37 kDa non-glycosylated protein expressed on the surface of normal and malignant B lymphocytes, and belongs to the MS4A (membrane-spanning 4-domain family A) protein family. CD20 protein consists of four hydrophobic transmembrane domains, one intracellular and two extracellular domains (large and small loops) with both N- and C- termini residing within the cytosol. CD20 is also known to be physically coupled to major histocompatibility complex class II (MHCII), CD40 molecule, BCR, a... | |||
TMPK-00142 |
APRIL/TNFSF13 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
TALL-2,CD256,TRDL1,APRILFLJ57090,APRIL,TNFSF13,2310026N09Rik... |
Human | HEK293 |
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFF R. | |||
TMPJ-00153 |
CD40 Ligand Protein, Human, Recombinant (His & Flag)
CD40LG,Tumor Necrosis Factor Ligand Superfamily Member 5,TRA... |
Human | Human Cells |
CD40 Ligand (CD40LG) is a type II transmembrane glycoprotein that belongs to the TNF superfamily. Like other TNF superfamily members, CD40LG exists as a trimer in membrane bound and soluble form, both of which are bioactive. CD40LG is a ligand for CD40; its ligation also initiates signal transduction in CD40LG expressing cells. CD40LG is a differentiation antigen that is expressed on the surface of T-cells. It stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the pr... | |||
TMPJ-01330 |
CD299 Protein, Human, Recombinant (His & Flag)
DC-SIGNR,L-SIGN,CD299,CD209L,LSIGN,C-type lectin domain fami... |
Human | Human Cells |
CD299 is also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called neck domain, mediates oligermerization. Multiple human DC-SIGN/CD209 splice forms exist, generating both membrane-bound and soluble forms. DC-SIGNR is ragarded as a pathogen-recognition receptor involved in peripheral immune surveillance in liver, and probably mediate the endocytosis of pathogens which are subsequently degraded in lysoso... | |||
TMPK-00108 |
NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag)
NKG2D,NKG2-D,CD314,KLR,D12S2489E |
Human | HEK293 |
NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate ligands. Human NKG2D is expressed on CD8 alpha beta T cells, gamma δ T cells, NK cells and NKT cells. | |||
TMPK-00444 |
SARS-COV-2 Spike S1 NTD Protein (His & Flag)
S1 protein NTD,Spike glycoprotein Subunit1 NTD,S glycoprotei... |
SARS-CoV-2 | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. | |||
TMPJ-00694 |
BRD4 Protein, Human, Recombinant (His & Flag)
MCAP,HUNK1,HUNKI,bromodomain-containing protein 4 |
Human | E. coli |
Bromodomain-containing protein 4 (BRD4) is a member of the BET class chromatin reader proteins that bind acetylated histones and play a key role in transcriptional regulation and transmission of epigenetic memory. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for postmitotic G1 gene transcription by preserving acetylated chromatin status and maintaining high-order chromatin structure. BRD bromodomains serve as recognition motifs for ... | |||
TMPK-00175 |
BAFF/TNFSF13B Protein, Human, Recombinant (monomeric hFc, Flag)
THANK,TALL1δ4 BAFF,TALL1Delta4 BAFF,TALL1,TNFSF20,TALL-1delt... |
Human | HEK293 |
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. | |||
TMPJ-01028 |
Claudin-18.2 Protein, Human, Recombinant (Twin strep & Flag)
Claudin 18.2,CLDN18,Claudin-18,CLDN18.2,Claudin-18.2 |
Human | Human Cells |
Claudin-18 (CLDN18) is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. CLDN18 has two isoform A1 and isoform A2. Human CLDN18.2 is highly expressed in a signifcant proportion of gastric and pancreat... | |||
TMPY-05243 |
CD3D Protein, Human, Recombinant (hFc & FLAG), Biotinylated
CD3 delta,CD3-δ,CD3d molecule, δ (CD3-TCR complex),CD3d mole... |
Human | HEK293 |
T-cell surface glycoprotein CD3 delta chain, also known as CD3D, is a single-pass type I membrane protein. CD3D, together with CD3-gamma, CD3-epsilon and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. The majority of T cell receptor (TCR) complexes in mice and humans consist of a heterodimer of polymorphic TCR alpha and beta chains along with invariant CD3 gamma, delta, epsilon, and zeta chains. T cell receptor-CD3 complex plays ... | |||
TMPJ-00669 |
Siglec-5 Protein, Human, Recombinant (His & Flag & hFc)
Sialic acid-binding Ig-like lectin 5,OB-BP2,Obesity-binding ... |
Human | Human Cells |
Human Siglec-5 are Itype(Igtype) lectins belonging to the Ig superfamily,They are characterized by an N terminal Ig-like V type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2 type domains. SIGLEC5 has also been designated CD170, they are expressed by monocytic or myeloid lineage cells, and also found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. SIGLEC5 are... | |||
TMPK-00650 |
HLA-A*02:01 & B2M & MART-1 (ELAGIGILTV) Monomer Protein, Cynomolgus, Recombinant (His)
IL10A,GVHDS,IL-10,MGC126451,B-TCGF,MGC126450,TGIF,CSIF,Inter... |
Cynomolgus | HEK293 |
Interleukin 10 (IL10) is a key anti-inflammatory cytokine that can inhibit proinflammatory responses of both innate and adaptive immune cells. An association between IL10 and intestinal mucosal homeostasis became clear with the discovery that IL10 and IL10 receptor (IL10R)-deficient mice develop spontaneous intestinal inflammation. Similarly, patients with deleterious mutations in IL10, IL10RA, or IL10RB present with severe enterocolitis within the first months of life. | |||
TMPK-00926 |
Noggin/NOG Protein, Mouse, Recombinant (His & Flag)
SYNS1,NOG,SYM1,Noggin |
Mouse | HEK293 |
Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer Genome Atlas human GC cohort. Targeting EGFR and its downstream pathways diminished cell proliferation which was promoted by Noggin. Noggin promotes the proliferation of GC cells by upregulating EGFR and enhancing a vicious circle formed by β‑catenin, EGFR, ERK and Akt. | |||
TMPK-01159 |
MFAP4 Protein, Mouse, Recombinant (His & Flag)
Mfap4,Microfibril-associated glycoprotein 4 |
Mouse | HEK293 |
Microfibril-associated glycoprotein 4 (MFAP4) is an extracellular matrix protein belonging to the fibrinogen-related protein superfamily. MFAP4 is produced by vascular smooth muscle cells and is highly enriched in the blood vessels of the heart and lung, where it is thought to contribute to the structure and function of elastic fibers. Genetic studies in humans have implicated MFAP4 in the pathogenesis of Smith-Magenis syndrome, in which patients present with multiple congenital abnormalities an... | |||
TMPK-00535 |
FGL2 Protein, Cynomolgus, Recombinant (His & Avi, Flag)
fibrinogen-like 2,FGL2,pT49,Fibroleukin |
Cynomolgus | HEK293 |
Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. FGL2 is overexpressed in glioma, and its expression level is negatively associated with the prognosis of glioma patients. | |||
TMPK-00968 |
FGL2 Protein, Human, Recombinant (His & Avi, Flag)
pT49,Fibroleukin,FGL2,fibrinogen-like 2 |
Human | HEK293 |
Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. FGL2 is overexpressed in glioma, and its expression level is negatively associated with the prognosis of glioma patients. | |||
TMPH-00210 |
Flagellin Protein, Borrelia burgdorferi, Recombinant (His & SUMO)
|
Borrelia burgdorferi | E. coli |
Component of the core of the flagella. | |||
TMPH-00328 |
Flagellin B(flaB) Protein, Campylobacter jejuni, Recombinant (His)
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Campylobacter jejuni | E. coli |
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | |||
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