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40

抑制剂 & 化合物

93

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T78627	Chinese gallotannin	Others	Others
	Chinese gallotannin，一种非特异性α-amylase抑制剂，对人唾液α-淀粉酶具有较强的抑制作用，其Ki值为0.82 μg/mL。此化合物可用于糖尿病研究。
T64850	Chinese Pharmacopoeia Compound Library
	Chinese Pharmacopoeia Compound Library 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64850。
TP1425	Motilin (26-47), human, porcine 胃动素 (人类，猪)	Motilin Receptor	GPCR/G Protein
	Motilin (26-47), human, porcine 是内源性 motilin 受体的激动剂，在中国仓鼠卵巢细胞中，Ki 值和EC50值分别为 2.3 和 0.3 nM。
T31773	Fenlean FLZ
	Fenlean (FLZ) is currently conducting a phase I trial in the Institute of pharmacy, Chinese Academy of medical sciences as a potential treatment for Parkinson's disease.
T21808	Inotilone	Others	Others
	Inotilone 是中药材 Inonotus linteus 的主要成分，可用于转移性肺癌细胞的研究。
T6788	Bitopertin Paliflutine,比拓喷丁,RO4917838,RG1678,比托派汀	GlyT	Neuroscience
	Bitopertin (Paliflutine) 是一种有效的甘氨酸转运蛋白 1 (GlyT1) 抑制剂，对人 hGlyT1b 的 Ki 为 8.1 nM。
T22641	CDPPB	GluR	Neuroscience
	CDPPB 是选择性和脑渗透性的代谢型谷氨酸受体亚型5 (mGluR5) 阳性变构的调节剂，在表达人类 mGluR5 的中国仓鼠卵巢细胞中的 EC50值为 27 nM。它为开发抗精神病药提供了一种可能性。
T9916	Alirocumab	Others	Others
	Alirocumab 是 PCSK9的人单克隆抗体。它能够特异性结合肝脏低密度脂蛋白 (LDL) 受体的下调剂 PCSK9，增强肝脏结合 LDL-胆固醇 (LDL-C) 的能力，降低血液中的 LDL-C 水平。它可用于研究高胆固醇血症。
T77796	DL-Borneol (endo)-Borneol,Borneol,(±)-Borneol	GABA Receptor; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism; Neuroscience
	DL-Borneol ((endo)-Borneol) 是一种从中药中提取的小分子，是一种可口服的生物佐剂，可以改善药物向大脑的输送，常用作治疗心脑血管疾病的中药的辅助成分。
T12970	Solabegron GW 427353,3'-[[2-[(2R)-2-(3-氯苯基)-2-羟基乙基]氨基]乙基]氨基]-[1,1'-联苯基]-3-羧酸	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Solabegron (GW 427353) 是一种β3肾上腺素能受体 (β3-AR)的选择性激动剂, 在中国仓鼠卵巢细胞中测得 EC50=22 nM，可用于研究膀胱过度活跃和肠易激综合征。
T8785	HALOFUGINONE LACTATE	DNA/RNA Synthesis; TGF-beta/Smad	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Stem Cells
	HALOFUGINONE LACTATE 是 febrifugine 的卤化衍生物，它是一种天然的含有喹唑啉酮的化合物，存在于中草药 D. febrifuga 中。Halofuginone 以 ATP 依赖性方式抑制脯氨酰-tRNA 合成酶，Ki 为 18.3 nM。 Halofuginone 是 I 型胶原合成的特异性抑制剂，通过抑制 TGF-β 活性来减轻骨关节炎 (OA)
T16390	Omtriptolide	ERK	MAPK
	Omtriptolide, triptolide purified from the Chinese herb, is a water-soluble derivative prodrug.
T34482	Sachaliside
	Sachaliside is a compound isolated from Rhodiola rosea L. that is used in Chinese traditional medicine.
T30866	CH-100 CH100,UNII-25L08K1NAI,CH100;UNII-25L08K1NAI
	CH-100 is a Chinese herbal medicine previously used in the treatment of human hepatitis C.
T32215	Isoline Ruwenine
	Isoline is a pyrrolizidine alkaloid isolated from the traditional Chinese medicine Ligularia duciformis.
T82511	Ebdarokimab
	Ebdarokimab (AK101)，一种人源化IgG1-κ抗体，其表达系统主要选用CHO（中国仓鼠卵巢）细胞。
T82507	Ecleralimab CSJ-117,NVP-CSJ117
	Ecleralimab (CSJ-117; NVP-CSJ117) 是一种 Fab-IgG1-λ2 类型的单克隆抗体，专一性靶向胸腺基质淋巴生成素（TSLP）。该抗体主要采用 CHO（Chinese Hamster Ovary）细胞表达系统生产。
T80602	Dovanvetmab ZTS-00521505
	Dovanvetmab (ZTS-00521505)，一种IgG1-κ型抗体，专一性靶向Felcat IL31，由CHO（Chinese Hamster Ovary）细胞主要表达。
T80603	Dresbuxelimab AK-119	CD73	Immunology/Inflammation
	Dresbuxelimab (AK-119) 为靶向CD73的IgG-κ型单克隆抗体，常用CHO（中国仓鼠卵巢）细胞作为表达系统。
T80611	Sasanlimab PF-06801591	PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
	Sasanlimab（PF-06801591），一种人源化IgG4-κ抗PD-1抗体，由CHO（中国仓鼠卵巢）细胞主要表达。
T26776	Berteroin OR-009512,KB-47947,LP-088984,KB47947,LP088984
	Berteroin is an erucin homolog and potential antioxidant. It is present in cruciferous vegetables, including rucola salad leaves, Chinese cabbage and mustard oil. It decreases the release of pro-inflammatory cytokines in LPS-stimulated macrophages. It als
T80614	Serclutamab DC-1630423,PR-1594407	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Serclutamab是一种针对EGFR的IgG1-κ型人源化嵌合抗体，主要通过CHO（中国仓鼠卵巢）细胞进行表达。
T80608	Ebronucimab AK102
	Ebronucimab (AK102)为一种针对PCSK9的IgG1-λ2单克隆抗体，其主要源自经过工程化改造的CHO DG44细胞系。
T26770	Bencycloquidium Bromide BCQB
	Bencycloquidium Bromide is a muscarinic M3 antagonist. Bencycloquidium bromide inhibits nasal hypersecretion in a rat model of allergic rhinitis. Bencycloquidium Bromide showed high affinity toward the M(3) receptor in Chinese hamster ovary (CHO) cells (M
T80596	Coprelotamab GB-221	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Coprelotamab (GB-221) 为针对EGFR2的IgG-κ类单克隆抗体。该化合物通常在CHO DG44 (中国仓鼠卵巢) 细胞中表达。
T38358	1,3-Distearoyl-2-Oleoyl-rac-glycerol
	1,3-Distearoyl-2-oleoyl-rac-glycerol is a triacylglycerol that contains stearic acid at the sn-1 and sn-3 positions and oleic acid at the sn-2 position. It has been found in Kpangnana, Chinese tallow, and cocoa butters. 1,3-Distearoyl-2-oleoyl-rac-glycerol increases the phagocytic function of reticulo-endothelial cells in mice when administered at doses of 5 and 10 mg per animal.
T35685	2-hydroxy-6-Methylbenzoic Acid
	2-hydroxy-6-Methylbenzoic acid is a constituent of G. anandria, a well-known traditional Chinese medicinal herb, and also produced in various fungi, including P. patulum, where it is a precursor to the toxin patulin . This polyketide is a key structural moiety for many different antibiotic and anticancer agents, including chlorothricin , maduropeptin, neocarzinostatin, and terreic acid.
T71483	Streptonigrin (racemate)
	Streptonigrin is an aminoquinone antitumor and antibacterial antibiotic produced by Streptomyces flocculus. Streptonigrin inhibits β-Catenin/Tcf signaling and shows cytotoxicity in β-catenin-activated cells. Streptonigrin induces delayed chromosomal instability involving interstitial telomeric sequences in Chinese hamster ovary cells. Note: Streptonigrin from natural resource is (-)-rotation, has CAS#3930-19-6 and is a R-isomer.
T82501	Efavaleukin alfa AMG592
	Efavaleukin alfa (AMG592) 是一种人源化的单克隆抗体，由 IGHG1 Fc 片段与 IL-2 融合构成。其表达体系一般采用 CHO (中国仓鼠卵巢) 细胞。
T64298	Turoctocog alfa
	Turoctocog alfa 是一种来源于中国仓鼠卵巢 (CHO) 细胞的重组凝血因子 VIII (FVIII)。Turoctocog alfa 能够用于研究 A 型血友病。
T82696	Cofetuzumab PF-06523435,hu24
	Cofetuzumab (PF-06523435)为针对PTK7的人源化IgG1-κ亚型单克隆抗体，常在CHO（中国仓鼠卵巢）细胞表达体系中生产。
T80598	Davoceticept CD80 vIgD-Fc,ALPN-202
	Davoceticept (ALPN-202; CD80 vIgD-Fc) 是一种靶向CTLA-4的单克隆抗体。它包含CD80的(1-107)片段，该片段通过肽基连接子与IGHG1 Fc连接。Davoceticept通常在CHO（中国仓鼠卵巢）细胞中表达。
T67757	(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one	Immunology/Inflammation related	Immunology/Inflammation
	(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one 是青藤碱的主要代谢物。青藤碱是来源于青藤的代谢物。(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one 显示出抗炎活性。
T75792	Huwentoxin XVI TFA
	Huwentoxin XVI TFA，一种来自鸟蛛 Ornithoctonus huwena 的止痛剂，一种高度可逆和选择性的哺乳动物 N 型钙通道 (N-type calcium channel) (IC50约为 60 nM) 拮抗剂。Huwentoxin XVI TFA 对电压门控的 T 型钙通道，钾通道或钠通道没有影响。
T27647	J-104132 L753037,L 753037,J104132,J 104132,L-753037
	J-104132 is a potetn and selective endothelin A/B receptor antagonist (Ki: cloned human ETA = 0.034 nM; cloned human ETB = 0.104 nM) . In vitro, J-104132 is a potent antagonist of ET-1-induced accumulation of [3H]inositol phosphates in Chinese hamster ova
T80499	Jingzhaotoxin XI JZTX-XI	Sodium Channel	Membrane transporter/Ion channel
	Jingzhaotoxin XI (JZTX-XI) 为抑制钠电导的化合物，其IC50值为124 nM。该化合物能够减缓CHO-K1细胞中Nav1.5通道的快速失活，EC50值为1.18±0.2 μM。
T69056	Albizziin
	Albizziin is amino acid analog which acts as a competitive inhibitor of asparagine synthetase with respect to glutamine. Albizziin has been used to isolate mutants of Chinese hamster ovary cells with alterations in levels of the target enzyme. Several classes of mutations can be distinguished on the basis of cross-resistance to beta-aspartyl hydroxamate, another amino acid analog. Studies on asparagine synthetase indicate that resistance to albizziin may be due to altered regulation of asparagin...
T60990	U92016A hydrochloride
	U92016A hydrochloride 是口服有效的5-HT1A 受体激动剂，代谢稳定。U92016A hydrochloride 表现出极高的内在活性，能够以高亲和力结合中国仓鼠卵巢细胞中表达的人 5-HT1A 受体，Ki 值为0.2 nM。
T37548	azido-FTY720 azido-FTY720
	FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analog of sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 is phosphorylated by sphingosine kinase, which then acts as a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4, and S1P5). Down-regulation of S1P1 recept...
T80174	BmP02	Potassium Channel	Membrane transporter/Ion channel
	BmP02是源自中国蝎(Buthus martensi Karsch)毒液的化合物，功能为选择性Kv1.3通道阻断剂及对Kv4.2具有高选择性的调节剂。该化合物能够在HEK293T细胞中延缓Kv4.2的失活过程，EC50值约为850 nM。此外，BmP02能抑制心室肌细胞中的瞬时外向钾电流(Ito)。

化合物

Chinese gallotannin

Cat.No: T78627

Target: Others

Chinese Pharmacopoeia Compound Library

Cat.No: T64850

Motilin (26-47), human, porcine

Cat.No: TP1425

Synonym: 胃动素 (人类，猪)

Target: Motilin Receptor

Cat.No: T31773

Synonym: FLZ

Cat.No: T21808

Target: Others

Cat.No: T6788

Synonym: Paliflutine,比拓喷丁,RO4917838,RG1678,比托派汀

Target: GlyT

Cat.No: T22641

Target: GluR

Cat.No: T9916

Target: Others

Cat.No: T77796

Synonym: (endo)-Borneol,Borneol,(±)-Borneol

Target: GABA Receptor, Endogenous Metabolite

Cat.No: T12970

Synonym: GW 427353,3'-[[2-[(2R)-2-(3-氯苯基)-2-羟基乙基]氨基]乙基]氨基]-[1,1'-联苯基]-3-羧酸

Target: Adrenergic Receptor

HALOFUGINONE LACTATE

Cat.No: T8785

Target: DNA/RNA Synthesis, TGF-beta/Smad

Cat.No: T16390

Target: ERK

Cat.No: T34482

Cat.No: T30866

Synonym: CH100,UNII-25L08K1NAI,CH100;UNII-25L08K1NAI

Cat.No: T32215

Synonym: Ruwenine

Cat.No: T82511

Cat.No: T82507

Synonym: CSJ-117,NVP-CSJ117

Cat.No: T80602

Synonym: ZTS-00521505

Cat.No: T80603

Synonym: AK-119

Target: CD73

Cat.No: T80611

Synonym: PF-06801591

Target: PD-1/PD-L1

Cat.No: T26776

Synonym: OR-009512,KB-47947,LP-088984,KB47947,LP088984

Cat.No: T80614

Synonym: DC-1630423,PR-1594407

Target: EGFR

Cat.No: T80608

Synonym: AK102

Bencycloquidium Bromide

Cat.No: T26770

Synonym: BCQB

Cat.No: T80596

Synonym: GB-221

Target: EGFR

1,3-Distearoyl-2-Oleoyl-rac-glycerol

Cat.No: T38358

2-hydroxy-6-Methylbenzoic Acid

Cat.No: T35685

Streptonigrin (racemate)

Cat.No: T71483

Efavaleukin alfa

Cat.No: T82501

Synonym: AMG592

Turoctocog alfa

Cat.No: T64298

Cat.No: T82696

Synonym: PF-06523435,hu24

Cat.No: T80598

Synonym: CD80 vIgD-Fc,ALPN-202

(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one

Cat.No: T67757

Target: Immunology/Inflammation related

Huwentoxin XVI TFA

Cat.No: T75792

Cat.No: T27647

Synonym: L753037,L 753037,J104132,J 104132,L-753037

Jingzhaotoxin XI

Cat.No: T80499

Synonym: JZTX-XI

Target: Sodium Channel

Cat.No: T69056

U92016A hydrochloride

Cat.No: T60990

Cat.No: T37548

Synonym: azido-FTY720

Cat.No: T80174

Target: Potassium Channel

Cat. No.	Product Name	Target	Signaling Pathways
T38815	Millepachine	Apoptosis	Apoptosis
	Millepachine 是分离自中草药Millettia pachycarpaBenth 的查尔酮，在体内外对多种人类癌细胞均显示出强大的抗增殖作用。
T8304	Anisodamine Hydrobromide 6-Hydroxyhyoscyamine,氢溴酸山莨菪碱	Adrenergic Receptor; AChR	GPCR/G Protein; Neuroscience
	Anisodamine Hydrobromide (6-Hydroxyhyoscyamine) 是来自颠茄的一种生物碱，具有抗氧化、抗炎活性。它也是一种非亚型的选择性毒蕈碱和烟碱类胆碱受体拮抗剂。
TN1076	Oleonuezhenide	Others	Others
	Oleonuezhenide 分离自 Fructus Ligustri Lucidi 中，具有神经保护活性。
T2999	Gastrodin 天麻素,Gastrodine	Others	Others
	Gastrodin (Gastrodine) 是中草药天麻的主要成分，具有抗炎活性，常用于研究头晕，癫痫，中风和痴呆症。
T2763	Panaxadiol 人参二醇,20(R)-Panaxadiol	Others; HIF/HIF Prolyl-Hydroxylase	Chromatin/Epigenetic; Metabolism; Others
	Panaxadiol (20(R)-Panaxadiol) 是从人参根中获得，具有神经保护和抗肿瘤作用，能够抑制程序性细胞死亡配体-1(PD-L1)的表达和肿瘤增殖。
T5S2139	Epimedin A1 朝藿定A1,Hexandraside F	Others	Others
	Epimedin A1 (Hexandraside F) 是一种黄酮类化合物，从常用中药淫羊藿中提取得到。
T3788	Rehmannioside A	Others	Others
	Rehmannioside A 是从中药地黄中提取的环烯醚萜苷。
T9144	Telekin	Others	Others
	Telekin 是一种从中草药 Carpesium divaricatum 中分离出来的 eudesmane 型倍半萜内酯化合物，据报道可强烈抑制癌细胞的增殖。
T13350	Wushanicaritin	Others	Others
	Wushanicaritin 在 DPPH 自由基清除活性测试中显示出显著的抗氧化活性，其IC50值为35.3 μM，具有抗肿瘤作用和抗炎活性。
T4S0217	HOMOPLANTAGININ	TNF; NF-κB	Apoptosis; NF-κB
	Homoplantaginin 是来自中药荔枝草的一种类黄酮，具有抗炎和抗氧化活性。
T4130	Complanatuside 沙苑子苷,Complanatoside	Others	Others
	Complanatuside (Complanatoside) 是一种黄酮类化合物，存在于中药沙苑子中。
TN6797	Isoneochamaejasmin A	Others	Others
	Isoneochamaejasmin A 是一种双黄酮类化合物，是一种广泛使用的中药 stellera chamaejasme L. 干燥根中的主要活性成分之一。
T5734	(+)-BORNEOL d-Borneol,(+)-冰片	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	(+)-BORNEOL (d-Borneol) 是一种天然的双环单萜，在中药中用于镇痛和麻醉；增强 GABA 受体活性，EC50 为 248 μM。
T2715	Tubeimoside I 土贝母苷甲I,Tubeimoside-1,Lobatoside-H	Apoptosis; Others	Apoptosis; Others
	Tubeimoside I (Tubeimoside-1) 是中药土贝母提取物，是一种抗肿瘤剂。
T3056	Bavachinin 补骨脂二氢黄酮加醚,补骨脂二氢黄酮甲醚,Bavachinin A,7-O-Methylbavachin	PPAR	DNA Damage/DNA Repair; Metabolism
	Bavachinin (Bavachinin A) 是一种具有抗炎症和抗血管生成作用的天然化合物。
TQ0240	6"-O-Apiosyl-5-O-Methylvisammioside	Others	Others
	6”-O-Apiosyl-5-O-Methylvisammioside 是中药颈复康的成分之一，颈复康具有活血通络，散风止痛的作用。
T2883	Syringic acid 3,5-dimethyl ether Gallic Acid,SYRA,3,5-dimethoxy-4-hydroxy Benzoic Acid,丁香酸,NSC 2129	Others; Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology; Others
	Syringic acid (3,5-dimethoxy-4-hydroxy Benzoic Acid) 能抑制低密度脂蛋白的氧化。
T5749	10-Deacetyl-7-xylosyl paclitaxel 10-Deacetyl-7-xylosyltaxol,10-Deacetyltaxol 7-Xyloside,7-Xylosyl-10-deacetyltaxol,7-木糖甙-10-脱乙酰基紫杉醇,10-Deacetylpaclitaxel 7-Xyloside	Others; Microtubule Associated	Cytoskeletal Signaling; Others
	10-Deacetyl-7-xylosyl paclitaxel (7-Xylosyl-10-deacetyltaxol) 是一种紫杉醇衍生物，具有改进的药理特性和更高的水溶性，用于治疗癌症。
T4587	Mirificin BCP10902,Puerarin Apioside,葛根素芹菜糖苷,芹糖葛根素苷	Tyrosinase	Proteases/Proteasome
	Mirificin (BCP10902) 是一种葛根中的异黄酮。它能够抑制酪氨酸酶(Tyrosinase)，IC50=12.66 μM。
T1719	Bufalin	ATPase	Membrane transporter/Ion channel
	Bufalin 是蟾酥中的一种成分，是Na+/K+-ATPase 抑制剂，具有抗肿瘤活性，可与其基 α1、α2 和 α3 结合，Kd 值分别为 42.5、45 和 40 nM。
T6S1880	Benzoylaconine 苯甲酰乌头原碱,Pikraconitin,Isaconitine,Benzoylaconitine	Others	Others
	Benzoylaconine (Isaconitine) 是一种中药附子生物碱。
T19056	Safflower yellow Saffron powder,Carthamas yellow,红花黄	Others	Others
	Safflower yellow (Saffron powder) 是提取自植物红花的花中，可用于研究心脑血管疾病。
T4955	saponaretin Isovitexin,Apigenin-6-C-glucoside,异牧荆素	Apoptosis; Antioxidant	Apoptosis; oxidation-reduction
	saponaretin 是许多中药的活性成分，具有多种活性，如抗氧化、抗炎、抗阿尔茨海默病（AD）作用等。
T3600	Licochalcone A	Caspase; UGT; Autophagy	Apoptosis; Autophagy; Metabolism; Proteases/Proteasome
	Licochalcone A 是从名药甘草中分离得到的黄酮类天然产物，具有抗癌功效，对UDP-葡萄糖醛酸转移酶 (UGTs) 具有广泛抑制活性。它对 UGT1A1、1A3、1A4、1A6、1A7、1A9 和 2B7 具有强烈的抑制作用，IC50和Ki 值均低于5 μM。
T1246	Bornyl acetate 乙酸冰片酯,Bornyl acetic ether,2-Camphanol acetate,乙酸龙脑酯,Isobornyl acetate	Apoptosis; IL Receptor	Apoptosis; Immunology/Inflammation
	Bornyl acetate (Isobornyl acetate) 是一种强效的芳香剂，是功效最强大的风味稀释因子之一，具有抗肿瘤活性。
T2794	Astilbin Neoastilbin,Taxifolin 3-O-rhamnoside,Isoastilbin,Taxifolin 3-rhamnoside,落新妇苷,Neoisoastilbin	TNF; NF-κB; Nrf2	Apoptosis; Immunology/Inflammation; NF-κB
	Astilbin (Neoastilbin) 是在圣约翰草和中药草药制剂中发现的一种黄酮类天然产物，抑制TNF-α表达和NF-κB 活化，可增强NRF2活化。
T3803	Specnuezhenide 特女贞苷,Nuzhenide,Nuezhenide	Others; NF-κB; Wnt/beta-catenin	Cytoskeletal Signaling; NF-κB; Others; Stem Cells
	Specnuezhenide (Nuezhenide) 是分离自女贞子的果实中。它可抑制 NF-κB 和 wnt/β-catenin 信号传导，进而抑制 IL-1β 诱导的软骨细胞炎症。它可在骨关节炎 (OA) 大鼠模型中发挥抗炎作用。
T3907	Tenuigenin Senegenin,Senegin,远志皂苷元	NF-κB; Caspase; Antibacterial	Apoptosis; Microbiology/Virology; NF-κB; Proteases/Proteasome
	Tenuigenin (Senegenin) 是从中草药远志根中分离出来的主要活性成分，用于中药，具有抗氧化和抗炎活性。它抑制 NF-κB 活化，预防金黄色葡萄球菌诱导的肺炎。
T13469	(±)-Huperzine A	AChE	Neuroscience
	(±)-Huperzine A 是一种从中药中提取的活性石松属生物碱。 (±)-Huperzine A 是一种特异性和可逆的乙酰胆碱酯酶抑制剂，可用于治疗阿尔茨海默病的研究。
T2S0257	Dehydroandrographolide succinate	Others; Influenza Virus	Microbiology/Virology; Others
	Dehydroandrographolide succinate 是从中药穿心莲中提取的一种天然产物，具有免疫刺激、抗感染和抗炎作用，有潜力研究病毒性肺炎和病毒性上呼吸道感染。
TN2023	8-Oxoepiberberine 氧化表小檗碱,Oxyepiberberine	Others	Others
	8-Oxoepiberberine (Oxyepiberberine) 是口服左金方剂后血清中产生的生物碱代谢物。其中左金方剂是一种中药，可以用于胃肠道疾病的研究。
T2729	Scoparone 滨蒿内酯,Escoparone,Scoparon,Aesculetin dimethyl ether,6,7-dimethoxycoumarin,6,7-Dimethylesculetin	Others	Others
	Scoparone (Aesculetin dimethyl ether) 是分离自毛蒿中，具有抗凝血，抗血管舒张作用和抗炎活性。
T6263	Safflower-yellow	Others	Others
	Safflower-yellow 是从植物红花（Carthamus tinctorius）的花中提取的，作为中药已广泛用于治疗心脑血管疾病。
T2722	Ligustrazine 川芎嗪,四甲基吡嗪,Tetramethylpyrazine	Apoptosis; Antioxidant	Apoptosis; oxidation-reduction
	Ligustrazine (Tetramethylpyrazine) 是从Ligusticum wallichii 中提取的一种烷基吡嗪，常在薯条、面包、茶、乳制品、豆制品等食物中作为香精。它对大鼠具有潜在的抗神经和抗炎活性。
T2944	Danshensu sodium salt Sodium Danshensu,(±)-DanShenSu sodium salt,丹参素钠,(±)-DanShenSu sodium sal	P450; Autophagy	Autophagy; Metabolism
	Danshensu sodium salt (Sodium Danshensu) 是从中国草本丹参中提取的一种天然产物，可以抑制去氧肾上腺素和CaCl2 在无Ca2+ 培养基中引起的血管收缩。
T0392	Artemisinin Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,青蒿素,Artemisinine	HCV Protease; Ferroptosis; Akt; Parasite	Apoptosis; Cytoskeletal Signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Artemisinin (Qinghaosu) 是一种倍半萜烯内酯，是从青蒿植物的地上部分分离的一种抗疟疾药物。它有神经保护和抗癌作用。
T2S0007	Ferulic acid sodium 阿魏酸钠,阿魏酸钠；3-甲氧基-4-羟基肉桂酸钠,Sodium ferulic,Ferulic acid sodium salt,Sodium ferulate	FGFR; Reactive Oxygen Species; 5-HT Receptor; Endogenous Metabolite	Angiogenesis; GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB; Tyrosine Kinase/Adaptors
	Ferulic acid sodium (Sodium ferulic) 是新型的成纤维细胞生长因子受体 1 (FGFR1) 抑制剂。它对于FGFR1和FGFR2的IC50分别为 3.78 and 12.5 μM。
T4034	Solamargine Solamargin,δ-Solanigrine,澳洲茄边碱	Apoptosis; p38 MAPK; P-gp; STAT	Apoptosis; JAK/STAT signaling; MAPK; Membrane transporter/Ion channel; Neuroscience; Stem Cells
	Solamargine (δ-Solanigrine) 是一种来源于茄属植物的类固醇 Solasodine 的衍生物，诱导非选择性细胞毒性和 P-gp 抑制作用。它通过下调 MMP-2 和 MMP-9 的表达和活性来显著抑制 HepG2 细胞的迁移和侵袭，在多种癌症中均表现出抗癌活性。
T8040	Cholesterol myristate 胆甾烯基豆蔻酸酯,Cholesteryl myristate,胆固醇肉豆蔻酸,Cholesteryl tetradecanoate	Others; Potassium Channel; GABA Receptor; Endogenous Metabolite; AChR	Membrane transporter/Ion channel; Metabolism; Neuroscience; Others
	Cholesterol myristate (Cholesteryl myristate) 是粗吻海龙中的一种类固醇，可与多种离子通道结合，例如nAChR、GABAA 受体和内向整流钾离子通道。
T3814	Isorhapontigenin Isorhapotogenin,异丹叶大黄素	Others; Autophagy	Autophagy; Others
	Isorhapontigenin (Isorhapotogenin) 是一种从中草药闭苞买麻藤中分离出的膳食多酚，诱导自噬并抑制浸润性膀胱癌的形成，有抗炎作用。
T3019	Physcion 大黄素甲醚,Physcione,Parietin,Rheochrysidin	Dehydrogenase; Antibacterial	Metabolism; Microbiology/Virology
	Physcion (Physcione) 是一种从中药大黄中分离的蒽醌，作为 6-磷酸葡萄糖酸脱氢酶的抑制剂，IC50和 Kd 值分别为 38.5 μM 和 26.0 μM。它具有通便、保肝、抗炎、抗菌、抗增殖、抗肿瘤作用。
T3S1227	Aristolactam I Aristolactam,Aristololactam I,马兜铃内酰胺I,Aristololactum	Apoptosis; Caspase	Apoptosis; Proteases/Proteasome
	Aristolactam I (Aristololactum) 是马兜铃酸 I (AA-I) 的主要代谢产物，参与导致肾损伤的过程。它具有细胞毒性，通过诱导半胱天冬酶 3 依赖性途径中的细胞凋亡介导。
TN6339	(R)-5-Hydroxy-1,7-diphenylheptan-3-one (5R)-Dihydroyashabushiketol,(R)-5-羟基-1,7-二苯基-3-庚酮	Others	Others
	(R)-5-Hydroxy-1,7-diphenylheptan-3-one ((5R)-Dihydroyashabushiketol) 是从中药材高良姜的根茎中提取的。它抑制茶碱刺激的鼠 B16 黑色素瘤 4A5 细胞中的黑色素生成。
T2754	Oxymatrine Oxysophoridine,氧化苦参碱,Matrine N-oxide	Influenza Virus; Autophagy; TGF-beta/Smad	Autophagy; Microbiology/Virology; Stem Cells
	Oxymatrine (Oxysophoridine) 是来自槐属物种根部的一种生物碱，具有抗炎，抗纤维化和抗肿瘤的作用。它是一种用于治疗乙型肝炎病毒的中药。它可抑制博卡病毒 MVC 复制，降低病毒基因表达并减少病毒感染诱导的细胞凋亡。它还可以抑制 iNOS 的表达和 TGF-β/Smad 通路。
T5769	Stachydrine Methyl hygrate betaine,水苏碱,L-stachydrine,Proline betaine,N,N-Dimethyl-L-proline	NF-κB; Endogenous Metabolite	Metabolism; NF-κB
	Stachydrine (N,N-Dimethyl-L-proline) 是中国草本植物益母草的主要成分，具有促进血液循环和消除血瘀的功效。Stachydrine (N,N-Dimethyl-L-proline) 能够抑制NF-κB 信号通路。
T2823	Crocin 西红花苷,藏红花,Gardenia Yellow,Alpha-Crocin,藏红花素	Others	Others
	Crocin (Gardenia Yellow) 是从Crocus sativus 柱头中分离出的主要成分，是一种营养保健品，具有抗炎，抗癌，抗抑郁和抗惊厥等强大的药理作用。
T4892	Melilotic acid 3-(2-Hydroxyphenyl)propionic acid,3-(2-羟苯基)丙酸	Endogenous Metabolite	Metabolism
	Melilotic acid (3-(2-Hydroxyphenyl)propionic acid) 是内源性代谢产物的一种。
T3427	Polydatin Piceid,虎杖苷,Polydotin Peceid	Apoptosis; Mitophagy; NF-κB; Autophagy	Apoptosis; Autophagy; NF-κB
	Polydatin (Piceid) 是从传统中药虎杖根中提取的一种天然产物，在多个实验模型中具有抗炎作用。它可抑制 G6PD，并诱导氧化和内质网应激。
T3891	Oroxylin A-7-O-glucuronide Oroxylin A Glucoronide,千层纸素A-7-0-Β-D-葡萄糖醛酸苷,Oroxyloside,Oroxylin A 7-O-beta-D-glucuronide	Others	Others
	Oroxylin A-7-O-glucuronide (Oroxylin A Glucoronide) 是一种类黄酮葡糖苷酸，提取自 Scutellaria baicalensis 干燥的根中，具有脯氨酰寡肽酶(POP)抑制作用。
T3026	(-)-Huperzine A HupA,石杉碱,Huperzine A,石杉碱甲	Apoptosis; AChR; AChE; iGluR	Apoptosis; Membrane transporter/Ion channel; Neuroscience
	(-)-Huperzine A (HupA) 是从中国梅花苔中分离得到的一种生物碱，具有神经保护活性。它是高特异性可逆的，具有血脑屏障渗透性的一种乙酰胆碱酯酶抑制剂，其IC50值为 82 nM。它也是 N-甲基-D-天冬氨酸受体的非竞争性拮抗剂，可研究神经退行性疾病，如阿尔茨海默病。
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天然产物

Cat.No: T38815

Target: Apoptosis

Anisodamine Hydrobromide

Cat.No: T8304

Synonym: 6-Hydroxyhyoscyamine,氢溴酸山莨菪碱

Target: Adrenergic Receptor, AChR

Cat.No: TN1076

Target: Others

Cat.No: T2999

Synonym: 天麻素,Gastrodine

Target: Others

Cat.No: T2763

Synonym: 人参二醇,20(R)-Panaxadiol

Target: Others, HIF/HIF Prolyl-Hydroxylase

Cat.No: T5S2139

Synonym: 朝藿定A1,Hexandraside F

Target: Others

Rehmannioside A

Cat.No: T3788

Target: Others

Cat.No: T9144

Target: Others

Cat.No: T13350

Target: Others

HOMOPLANTAGININ

Cat.No: T4S0217

Target: TNF, NF-κB

Cat.No: T4130

Synonym: 沙苑子苷,Complanatoside

Target: Others

Isoneochamaejasmin A

Cat.No: TN6797

Target: Others

Cat.No: T5734

Synonym: d-Borneol,(+)-冰片

Target: GABA Receptor

Cat.No: T2715

Synonym: 土贝母苷甲I,Tubeimoside-1,Lobatoside-H

Target: Apoptosis, Others

Cat.No: T3056

Synonym: 补骨脂二氢黄酮加醚,补骨脂二氢黄酮甲醚,Bavachinin A,7-O-Methylbavachin

Target: PPAR

6"-O-Apiosyl-5-O-Methylvisammioside

Cat.No: TQ0240

Target: Others

Cat.No: T2883

Synonym: 3,5-dimethyl ether Gallic Acid,SYRA,3,5-dimethoxy-4-hydroxy Benzoic Acid,丁香酸,NSC 2129

Target: Others, Endogenous Metabolite, Antibacterial

10-Deacetyl-7-xylosyl paclitaxel

Cat.No: T5749

Synonym: 10-Deacetyl-7-xylosyltaxol,10-Deacetyltaxol 7-Xyloside,7-Xylosyl-10-deacetyltaxol,7-木糖甙-10-脱乙酰基紫杉醇,10-Deacetylpaclitaxel 7-Xyloside

Target: Others, Microtubule Associated

Cat.No: T4587

Synonym: BCP10902,Puerarin Apioside,葛根素芹菜糖苷,芹糖葛根素苷

Target: Tyrosinase

Cat.No: T1719

Target: ATPase

Cat.No: T6S1880

Synonym: 苯甲酰乌头原碱,Pikraconitin,Isaconitine,Benzoylaconitine

Target: Others

Safflower yellow

Cat.No: T19056

Synonym: Saffron powder,Carthamas yellow,红花黄

Target: Others

Cat.No: T4955

Synonym: Isovitexin,Apigenin-6-C-glucoside,异牧荆素

Target: Apoptosis, Antioxidant

Cat.No: T3600

Target: Caspase, UGT, Autophagy

Cat.No: T1246

Synonym: 乙酸冰片酯,Bornyl acetic ether,2-Camphanol acetate,乙酸龙脑酯,Isobornyl acetate

Target: Apoptosis, IL Receptor

Cat.No: T2794

Synonym: Neoastilbin,Taxifolin 3-O-rhamnoside,Isoastilbin,Taxifolin 3-rhamnoside,落新妇苷,Neoisoastilbin

Target: TNF, NF-κB, Nrf2

Cat.No: T3803

Synonym: 特女贞苷,Nuzhenide,Nuezhenide

Target: Others, NF-κB, Wnt/beta-catenin

Cat.No: T3907

Synonym: Senegenin,Senegin,远志皂苷元

Target: NF-κB, Caspase, Antibacterial

(±)-Huperzine A

Cat.No: T13469

Target: AChE

Dehydroandrographolide succinate

Cat.No: T2S0257

Target: Others, Influenza Virus

8-Oxoepiberberine

Cat.No: TN2023

Synonym: 氧化表小檗碱,Oxyepiberberine

Target: Others

Cat.No: T2729

Synonym: 滨蒿内酯,Escoparone,Scoparon,Aesculetin dimethyl ether,6,7-dimethoxycoumarin,6,7-Dimethylesculetin

Target: Others

Safflower-yellow

Cat.No: T6263

Target: Others

Cat.No: T2722

Synonym: 川芎嗪,四甲基吡嗪,Tetramethylpyrazine

Target: Apoptosis, Antioxidant

Danshensu sodium salt

Cat.No: T2944

Synonym: Sodium Danshensu,(±)-DanShenSu sodium salt,丹参素钠,(±)-DanShenSu sodium sal

Target: P450, Autophagy

Cat.No: T0392

Synonym: Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,青蒿素,Artemisinine

Target: HCV Protease, Ferroptosis, Akt, Parasite

Ferulic acid sodium

Cat.No: T2S0007

Synonym: 阿魏酸钠,阿魏酸钠；3-甲氧基-4-羟基肉桂酸钠,Sodium ferulic,Ferulic acid sodium salt,Sodium ferulate

Target: FGFR, Reactive Oxygen Species, 5-HT Receptor, Endogenous Metabolite

Cat.No: T4034

Synonym: Solamargin,δ-Solanigrine,澳洲茄边碱

Target: Apoptosis, p38 MAPK, P-gp, STAT

Cholesterol myristate

Cat.No: T8040

Synonym: 胆甾烯基豆蔻酸酯,Cholesteryl myristate,胆固醇肉豆蔻酸,Cholesteryl tetradecanoate

Target: Others, Potassium Channel, GABA Receptor, Endogenous Metabolite, AChR

Isorhapontigenin

Cat.No: T3814

Synonym: Isorhapotogenin,异丹叶大黄素

Target: Others, Autophagy

Cat.No: T3019

Synonym: 大黄素甲醚,Physcione,Parietin,Rheochrysidin

Target: Dehydrogenase, Antibacterial

Cat.No: T3S1227

Synonym: Aristolactam,Aristololactam I,马兜铃内酰胺I,Aristololactum

Target: Apoptosis, Caspase

(R)-5-Hydroxy-1,7-diphenylheptan-3-one

Cat.No: TN6339

Synonym: (5R)-Dihydroyashabushiketol,(R)-5-羟基-1,7-二苯基-3-庚酮

Target: Others

Cat.No: T2754

Synonym: Oxysophoridine,氧化苦参碱,Matrine N-oxide

Target: Influenza Virus, Autophagy, TGF-beta/Smad

Cat.No: T5769

Synonym: Methyl hygrate betaine,水苏碱,L-stachydrine,Proline betaine,N,N-Dimethyl-L-proline

Target: NF-κB, Endogenous Metabolite

Cat.No: T2823

Synonym: 西红花苷,藏红花,Gardenia Yellow,Alpha-Crocin,藏红花素

Target: Others

Cat.No: T4892

Synonym: 3-(2-Hydroxyphenyl)propionic acid,3-(2-羟苯基)丙酸

Target: Endogenous Metabolite

Cat.No: T3427

Synonym: Piceid,虎杖苷,Polydotin Peceid

Target: Apoptosis, Mitophagy, NF-κB, Autophagy

Oroxylin A-7-O-glucuronide

Cat.No: T3891

Synonym: Oroxylin A Glucoronide,千层纸素A-7-0-Β-D-葡萄糖醛酸苷,Oroxyloside,Oroxylin A 7-O-beta-D-glucuronide

Target: Others

(-)-Huperzine A

Cat.No: T3026

Synonym: HupA,石杉碱,Huperzine A,石杉碱甲

Target: Apoptosis, AChR, AChE, iGluR

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