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Search Results for " wound "

61

抑制剂 & 化合物

24

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T21632	Myoseverin	Others; Microtubule Associated	Cytoskeletal Signaling; Others
	Myoseverina 是多核肌管可逆分裂成单核片段的诱导剂，影响多种生长因子、免疫调节、细胞外基质重塑和应激反应基因的表达，与伤口愈合和组织再生相关通路的激活一致。
T8575	ENFENAMIC ACID	Platelet aggregation	Others
	Enfenamic acid 是一种能够抑制伤口愈合的非甾体抗炎药。
T21653	1,4-DPCA	HIF/HIF Prolyl-Hydroxylase	Chromatin/Epigenetic; Metabolism
	1,4-DPCA 是一种脯氨酰羟化酶抑制剂，对人源包皮成纤维细胞中胶原羟基化的 IC50 为 2.4 μM，对因子抑制 HIF (FIH) 的 IC50 为 60 μM。
T16850	SB-265610 GSK-CXCR2	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	SB-265610 (GSK-CXCR2) 是竞争性非肽变构CXCR2选择性拮抗剂，可阻断大鼠 CINC-1 诱导的钙动员和中性粒细胞趋化性，IC50分别为 3.7 和 70 nM。
T4478	CID 16020046 C390-0219	Cannabinoid Receptor	GPCR/G Protein
	CID 16020046 (C390-0219) 是一种选择性 GPR55 拮抗剂，在酵母中抑制 GPR55 组成型活性，IC50 为 0.15 μM。它抑制 GPR55 介导的 Ca2+信号传导和 GPR55 介导的 ERK1/2 磷酸化，可降低内皮细胞的伤口愈合，参与血小板功能的调节。
T34685	Sonedenoson MRE-0094,MRE0094,MRE 0094
	Sonedenoson( MRE0094) is an adenosine A2A receptor agonist that promotes rapid wound healing.
T2206	Quadrol N,N,N′,N′-Tetrakis(2-hydroxypropyl)ethylenediamine,EDTP,依的托,Edetol	Others	Others
	Quadrol (EDTP) 是一种免疫刺激剂，是潜在的能够加速伤口愈合的有用药物。
T19841	Tribenoside Glyvenol,Glyvenal,Ba 2140,BG-356,Glivenol,三苄糖苷,TBGF	Others	Others
	Tribenoside (BG-356) 是血管保护剂，能够温和的镇痛、抗炎及伤口愈合，可用研究痔疮。
T13823	Polyvinylpyrrolidone PVP,Povidone,Polyvidone,聚乙烯吡咯烷酮	Others	Others
	Polyvinylpyrrolidone (Polyvidone) 与碘和其他化合物结合后，可用作人类和兽医学中有效的伤口愈合促进剂和消毒剂。
T0979	Dequalinium chloride Dequafungan,地喹氯铵,Danical,Decabis	Potassium Channel; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Membrane transporter/Ion channel
	Dequalinium chloride (Decabis) 是一种apamin 敏感型的钾离子通道选择性阻断剂。
T40570L	LKKTETQ acetate LKKTETQ acetate (476014-70-7 Free base)	Others	Others
	LKKTETQ acetate 是胸腺素 β4 蛋白中的活性位点，负责伤口愈合、肌动蛋白结合和细胞迁移。
T22408	Proflavine 吡啶-3,6-二胺,3,6-Diaminoacridine	Antibacterial	Microbiology/Virology
	Proflavine (3,6-Diaminoacridine) 是吖啶染料，可用作抗菌剂。它是 DNA 嵌入剂，能够阻滞Kir3.2孔。它用作与 Kir3.2 相关的神经系统疾病的研究。
T7116	Sodium gualenate Guaiazulenesulfonate sodium,磺酸钠	Others	Others
	Sodium gualenate (Guaiazulenesulfonate sodium) 是一种桂皮烯的亲水性衍生物，具有良好的抗炎和愈伤活性，常用于十二指肠溃疡，胃溃疡和胃炎的研究。
TP2319	Thymosin β4 acetate(75591-33-4 free base)	Autophagy	Autophagy
	Thymosin β4 acetate(75591-33-4 free base) 是一种胸腺激素，具有多种不同的细胞内和细胞外活性，影响伤口愈合、炎症、纤维化和组织再生。
T41206	Poly Vinyl Alcohol Polyvinyl alcohol	Others	Others
	Poly Vinyl Alcohol (Polyvinyl alcohol)是一种水溶性可生物降解且可用于伤口愈合的聚合物，在生物医学领域广泛使用。Poly Vinyl Alcohol 常用于制作医用辅料。
T74048	PAPA NONOate	Endogenous Metabolite; NO Synthase	Immunology/Inflammation; Metabolism
	PAPA NONOate 是一种依赖于 pH 调节的 NO 供体。PAPA NONOate 具有潜在的抗肿瘤活性，通过增加伤口部位的胶原合成率，可用于研究糖尿病伤口愈合障碍。
T21550	Blebbistatin (±)-Blebbistatin	ATPase; Myosin	Cytoskeletal Signaling; Membrane transporter/Ion channel
	Blebbistatin ((±)-Blebbistatin) 是一种选择性的非肌肉肌球蛋白 II 抑制剂，可促进角膜内皮细胞 (CEC) 的定向迁移并加速伤口愈合，并保留了细胞连接的完整性和屏障功能。
T77617	MMP-9-IN-6	MMP	Proteases/Proteasome
	MMP-9-IN-6 是一种 MMP-9 抑制剂，其 IC50 值为50 μM, 具有较好的抗溃疡功效。MMP-9-IN-6 具有潜在的抗肿瘤活性，可用于研究组织重塑、伤口修复和动脉粥样硬化。
T32613	LCB 03-0110 dihydrochloride	Src	Angiogenesis; Tyrosine Kinase/Adaptors
	LCB 03-0110 Dihydrochloride 是BTK 和SYK 家族以及DDR2家族中c-Src 激酶（IC50=1.3 nM）和酪氨酸激酶的有效抑制剂。在体外抑制LPS 诱导的巨噬细胞活化和TGF-β1诱导的成纤维细胞活化，抑制巨噬细胞和成纤维细胞的活化，并抑制伤口愈合模型中的瘢痕形成。
T4306	CCG-203971 CCG203971	Rho; Ras	Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
	CCG-203971 是一种Rho/MRTF/SRF 通路抑制剂，具有潜在的抗转移作用。它有效靶向 RhoA/C 激活的 SRE 荧光素酶，IC50为 6.4 μM。它抑制 PC-3 细胞迁移，IC50为 4.2 μM。
T4425	JK-P3	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	JK-P3 是广谱 VEGFR2抑制剂。它能够抑制 VEGF-A 刺激的 VEGFR2 激活和细胞内信号转导，也可阻碍内皮单层细胞迁移和血管生成，影响成纤维细胞生长因子受体激酶在体外的活性。它具有抗血管生成的作用。
T3616	Carbazochrome AC-17,Adrenostazin,Cromadrenal,Adona,Adchnon,卡巴克络,Adedolon	Others; Phospholipase	Metabolism; Others
	Carbazochrome (Adchnon) 是毛细管稳定剂，是抗出血剂，用于研究出血。
T41231	GP 1a	Cannabinoid Receptor; PERK; Arrestin	Apoptosis; GPCR/G Protein
	GP 1a 是cannabinoid receptor 2（CB2）的强效激动剂（EC50=7.1),是在cAMP、GTPγS 和β-arrestin 招募试验中显示的。GP 1a 对CB2受体的选择性约为CB1受体的30倍，且在体外增加HL-60细胞的P-ERK1/2表达。GP 1a 对皮肤伤口愈合有益。GP 1a 可抑制炎症和纤维生成，同时促进上皮的重新形成。
T34693	Sphingosine phosphorylcholine
	Sphingosine phosphorylcholine is a wound healing agent.
T28146	ND-336 ND336,ND-336 hydrochloride,ND 336
	ND-336 is a highly selective inhibitor ofMMP-2, MMP-9 and MMP-14. ND-336 accelerates diabetic wound healing by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound.
T29547	Acemannan Acemannanan
	Acemannan can produce cell proliferation and skin wound healing through AKT/mTOR signaling pathway.
T70826	PF-03671148
	PF-03671148 is a potent ALK inhibitor. PF-03671148 inhibits the expression of fibrotic genes and protein markers both in vitro in human fibroblasts and in vivo in a rat wound repair model. Wound healing is not inhibited by the topical application of the ALK5 inhibitor to the wound. PF-03671148 may have potential utility for the prevention of dermal scarring.
T20937	Dodecenylsuccinic anhydride 2-十二烯基-丁二酸酐,Rikacid DDSA,Dodecenylsuccinic acid anhydride,DDSA	Others	Others
	Dodecenylsuccinic anhydride (DDSA) 可与胶原水凝胶接枝，作为疏水性伤口敷料掺入辛伐他汀后，在治疗溃疡和预防伤口感染方面具有潜在应用。
T25309	Dermabond Liquid Bandage,2-Octyl 2-cyanoacrylate,RiteLok CON 895
	Dermabond 是一种抗菌化合物，已被用于伤口愈合的基础科学研究。
T30107	Apratyramide
	Apratyramide is a marine-derived peptidic stimulator of VEGF-A and other growth factors with potential application in wound healing.
T40570	LKKTETQ
	LKKTETQ, a peptide segment, is the active site within the protein thymosin β 4 responsible for actin binding, cell migration and wound healing.
T81330	Q-Peptide
	Q-Peptide（QHREDGS），是血管生成素-1的衍生肽。在糖尿病小鼠模型中，它通过增加角质形成细胞迁移来改善伤口愈合，并加速伤口闭合。
T21185	CEP03 CEP 03,CEP-03
	CEP03 enhances EC/EPC proliferation, tubelike formation, and wound-healing efficiency, leading to promote angiogenesis and significantly improve blood flow perfusion recovery in the ischemic hind limbs of mice.
T26958	CAY10583 CAY 10583,CAY-10583
	CAY10583 is an agonist of leukotriene B4 receptor type 2 (BLT2). CAY10583 directly promotes keratinocyte migration and indirectly enhances fibroblast proliferation by increasing keratinocyte production of bFGF1 and TGF-β, leadng to accelerate wound closur
T81404	Prezatide copper Bisprezatide copper,PC 1020,Iamin
	Prezatide Copper（亦称Iamin）具有促进伤口愈合的多重特性，且用于抑制脱发。
T14139	Aganepag AGN 210937	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Aganepag, a potent Prostanoid EP2 receptor agonist, exhibits remarkable selectivity with an EC50 of 0.19 nM, demonstrating no activity at the EP4 receptor. Its applications are primarily in the fields of wound healing, scar reduction, scar prevention, and the treatment and prevention of wrinkles.
T82358	G-{d-Arg}-GDSPASSK
	G-{d-Arg}-GDSPASSK是一种抑制细胞粘附的多肽，有助于促进伤口愈合和组织修复。
T34653	SK1071
	SK1071 is a novel migrastatin analogs, which demonstrated improved performance over migrastatin, with nanomolar IC50 values in chamber cell migration assays with tumor cells and human umbilical vein endothelial cells (HUVECs), and in wound healing assays.
T41189	AY 254
	AY 254 is a potent PAR2 biased agonist. Selectively activates ERK1/2 signaling (EC50= 2 nM for ERK1/2 phosphorylation versus 80 nM for Ca2+release). Reduces cytoKi ne-induced caspase 3/8 activation, promotes scratch-wound healing, and induces IL-8 secretion, in human colorectal cancer (HT29) cellsin vitro.
T61106	GRP78-IN-1
	GRP78-IN-1 displays interactions with specific residues on the GRP78 protein with a binding energy of -8.07 kcal/mol. This compound possesses potent cytotoxic and anti-proliferative effects on cancer cells, particularly demonstrating promising apoptosis in breast cancer cells and wound healing properties [1].
T76235L	Peceleganan acetate
	Peceleganan (PL-5) acetate，一种人工合成的肽类似物，由天蚕素 A (1-10) 和蜂毒素 B (3-18) 杂化而成，具有 (10+16) 的结构。该化合物有效抑制伤口感染。
T74392	Antimicrobial photosensitizer-1
	Antimicrobial photosensitizer-1 为抗病原微生物感染的潜在光敏剂，其在金黄色葡萄球菌感染小鼠伤口模型中显示出显著的抗菌活性。
T76235	Peceleganan
	Peceleganan (PL-5) 是一种合成的肽类似物，由天蚕素 A (1-10) × 蜂毒素 B (3-18) 杂化而成，具有 (10+16) 的结构。该化合物具有抑制伤口感染的作用。
T75857	LL-37, human TFA
	LL-37, human TFA 是一种由37个氨基酸残基组成的两亲性抗菌肽，源自组织蛋白酶，具备广谱抗菌活性。该化合物有助于防护角膜避免感染，同时调节伤口的愈合过程。
T36080	Rivenprost ONO-4819
	Prostaglandin E2 activates four distinct G protein-coupled receptors, EP1-4. Rivenprost is a potent and selective agonist for the EP4 receptor (Ki = 0.7, 56, 620, and >10,000 nM for EP4, EP3, EP2, and EP1, respectively). It has been used to promote EP4-mediated bone formation, prevent bone loss related to osteoporosis, drive osteoblast differentiation, and stabilize bone implants.[1][2][3][4][5] Rivenprost has also been used to support wound healing.[6]
T75858	LL-37, human acetate
	LL-37, human acetate 是一种由37个氨基酸残基组成的两亲性抗菌肽，源于组织蛋白酶的衍生物，展现出广泛的抗菌效果。该化合物不仅对角膜感染提供保护，也有助于调节伤口的愈合过程。
T74212	BLT2 probe 1	Leukotriene Receptor	GPCR/G Protein
	BLT2 probe 1 (化合物 13) 是一款以 CAY10583 合成激动剂为基础的荧光探针，主要靶向糖尿病伤口愈合和胃肠道病变中潜在的 BLT2。该探针适用于多种检测系统中对 BLT2 受体配体进行药理学研究。
T35671	Salazinic Acid
	Salazinic acid is a depsidone lichen metabolite that has been found in P. sulcata.1 It is active against B. cereus, B. subtilis, S. aureus, P. aeruginosa, S. typhimurium, C. albicans, and A. niger in vitro (MICs = 3.9-30.8 mM). Salazinic acid is cytotoxic to MM98, A431, and HaCaT cells in crystal violet (EC50s = 159, 2,870, and 48 μM, respectively) and neutral red uptake assays (EC50s = 1,925, 1,913, and 907 μM, respectively).2 It increases the wound closure rate in scratch-wounded HaCaT monolay...
T35408	(±)10(11)-EDP Ethanolamide
	(±)10(11)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 0.43 and 22.5 nM for CB1 and CB2 receptors, respectively). It is produced though direct epoxygenation of docosahexaenoyl ethanolamide by cytochrome P450 (CYP) epoxygenases. 10,11-EDP epoxide (12.5 and 25 μM) reduces the viability of 143B metastatic osteosarcoma cells. It induces apoptosis and inhibits cell migration in a wound-healing assay in 143B, MG63, and HOS osteosarcoma cells. (±)10(...
T80859	Vitronectin
	Vitronectin为一类多功能糖蛋白，广泛分布于血液及细胞外基质。该蛋白质与糖胺聚糖、胶原蛋白、纤溶酶原及尿激酶受体发生结合，并对纤溶酶原激活抑制剂1的抑制构象起稳定作用。Vitronectin常用于促进伤口愈合和肿瘤进展研究领域。

化合物

Cat.No: T21632

Target: Others, Microtubule Associated

Cat.No: T8575

Target: Platelet aggregation

Cat.No: T21653

Target: HIF/HIF Prolyl-Hydroxylase

Cat.No: T16850

Synonym: GSK-CXCR2

Target: CXCR

Cat.No: T4478

Synonym: C390-0219

Target: Cannabinoid Receptor

Cat.No: T34685

Synonym: MRE-0094,MRE0094,MRE 0094

Cat.No: T2206

Synonym: N,N,N′,N′-Tetrakis(2-hydroxypropyl)ethylenediamine,EDTP,依的托,Edetol

Target: Others

Cat.No: T19841

Synonym: Glyvenol,Glyvenal,Ba 2140,BG-356,Glivenol,三苄糖苷,TBGF

Target: Others

Polyvinylpyrrolidone

Cat.No: T13823

Synonym: PVP,Povidone,Polyvidone,聚乙烯吡咯烷酮

Target: Others

Dequalinium chloride

Cat.No: T0979

Synonym: Dequafungan,地喹氯铵,Danical,Decabis

Target: Potassium Channel, PKC

LKKTETQ acetate

Cat.No: T40570L

Synonym: LKKTETQ acetate (476014-70-7 Free base)

Target: Others

Cat.No: T22408

Synonym: 吡啶-3,6-二胺,3,6-Diaminoacridine

Target: Antibacterial

Sodium gualenate

Cat.No: T7116

Synonym: Guaiazulenesulfonate sodium,磺酸钠

Target: Others

Thymosin β4 acetate(75591-33-4 free base)

Cat.No: TP2319

Target: Autophagy

Poly Vinyl Alcohol

Cat.No: T41206

Synonym: Polyvinyl alcohol

Target: Others

Cat.No: T74048

Target: Endogenous Metabolite, NO Synthase

Cat.No: T21550

Synonym: (±)-Blebbistatin

Target: ATPase, Myosin

Cat.No: T77617

Target: MMP

LCB 03-0110 dihydrochloride

Cat.No: T32613

Target: Src

Cat.No: T4306

Synonym: CCG203971

Target: Rho, Ras

Cat.No: T4425

Target: VEGFR

Cat.No: T3616

Synonym: AC-17,Adrenostazin,Cromadrenal,Adona,Adchnon,卡巴克络,Adedolon

Target: Others, Phospholipase

Cat.No: T41231

Target: Cannabinoid Receptor, PERK, Arrestin

Sphingosine phosphorylcholine

Cat.No: T34693

Cat.No: T28146

Synonym: ND336,ND-336 hydrochloride,ND 336

Cat.No: T29547

Synonym: Acemannanan

Cat.No: T70826

Dodecenylsuccinic anhydride

Cat.No: T20937

Synonym: 2-十二烯基-丁二酸酐,Rikacid DDSA,Dodecenylsuccinic acid anhydride,DDSA

Target: Others

Cat.No: T25309

Synonym: Liquid Bandage,2-Octyl 2-cyanoacrylate,RiteLok CON 895

Cat.No: T30107

Cat.No: T40570

Cat.No: T81330

Cat.No: T21185

Synonym: CEP 03,CEP-03

Cat.No: T26958

Synonym: CAY 10583,CAY-10583

Prezatide copper

Cat.No: T81404

Synonym: Bisprezatide copper,PC 1020,Iamin

Cat.No: T14139

Synonym: AGN 210937

Target: Prostaglandin Receptor

G-{d-Arg}-GDSPASSK

Cat.No: T82358

Cat.No: T34653

Cat.No: T41189

Cat.No: T61106

Peceleganan acetate

Cat.No: T76235L

Antimicrobial photosensitizer-1

Cat.No: T74392

Cat.No: T76235

LL-37, human TFA

Cat.No: T75857

Cat.No: T36080

Synonym: ONO-4819

LL-37, human acetate

Cat.No: T75858

Cat.No: T74212

Target: Leukotriene Receptor

Cat.No: T35671

(±)10(11)-EDP Ethanolamide

Cat.No: T35408

Cat.No: T80859

Cat. No.	Product Name	Target	Signaling Pathways
T3855	Tracheloside	Estrogen Receptor/ERR; Phosphorylase	Endocrinology/Hormones; Metabolism
	Tracheloside 是抗雌激素木质素，利用 ERK1/2 刺激促进角质形成细胞增殖，是一种良好的促进伤口愈合的药物。
T3881	Vaccarin	Integrin; Akt; PERK; AMPK	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	Vaccarin 是从王不留行中提取的一种黄酮糖苷，可显著促进伤口愈合以及伤口部位的内皮和成纤维细胞增殖。它通过激活 AMPK 信号通路改善胰岛素抵抗和脂肪变性。
T5S1982	Periplocin Periplocoside,杠柳毒苷	Apoptosis; Others	Apoptosis; Others
	Periplocin (Periplocoside) 是从黑龙骨中分离出的一种强心类固醇。它可促进肿瘤细胞凋亡并抑制肿瘤生长。它通过激活 Na/K-ATPase 介导的 Src/ERK 和 PI3K/Akt 途径，具有促进伤口愈合的潜力。
TN1686	Ginsenoside Rg4 人参皂苷 RG4	Antibacterial	Microbiology/Virology
	Ginsenoside Rg4 是分离自Panax ginsengC. A. Meyer 叶子中的一种人参三醇型人参皂苷。人参三醇型人参皂苷具有多种生物活性，包括防腐，抗糖尿病，伤口愈合，免疫刺激和抗氧化活性等。
TN3016	4',6,7-Trimethoxyisoflavone	MMP	Proteases/Proteasome
	4',6,7-Trimethoxyisoflavone 通过 NOX2 诱导促进伤口愈合，从而导致集体迁移和 MMP 活化。
TN1079	Deoxyelephantopin	NF-κB	NF-κB
	Deoxyelephantopin 是来自Elephantopus scaber 的，具有生物活性的天然倍半萜烯内酯，能够抑制NF-κB，MAPK，PI3K/Akt 和β-catenin 信号传导。它可广泛用于癌症方面的研究。
T2827	Asiatic acid Asiantic acid,Dammarolic acid,积雪草酸	Apoptosis; p38 MAPK; Parasite	Apoptosis; MAPK; Microbiology/Virology
	Asiatic acid (Dammarolic acid) 是在Centella asiatica 中发现的一种五环三萜，有抗炎活性，可诱导黑色素瘤细胞的凋亡，有可能治疗皮肤癌。
T1125	Shikonin NSC 252844,Isoarnebin 4,(+)-Shikonin,紫草素,Alkanna Red,C.I. 75535,Anchusa acid	TNF; NF-κB; Chloride channel; HIV Protease; PKM	Apoptosis; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	Shikonin (Anchusa acid) 属于天然产物，是一种 TMEM16A 氯离子通道抑制剂 (IC50=6.5 μM) 和选择性 PKM2 抑制剂。Shikonin 具有抗肿瘤、抗炎和伤口愈合活性。
TN2077	(+/-)-Pinocembrin NSC 43318,(±)-5,7-Dihydroxyflavanone	GPR; Others	Endocrinology/Hormones; GPCR/G Protein; Others
	(+/-)-Pinocembrin (NSC-43318) 是一种来自腋松的天然产物，它是一种 GPR120 配体，能促进 HaCaT 细胞系的伤口愈合。
TN6926	Paeonoside	Others	Others
	Paeonoside 发现与P. suffruticosa 中，具有生物活性，可以促进成骨细胞分化过程中的伤口愈合和迁移。Paeonoside 具有一定的抗糖尿病活性，可防止脓毒症和败血症引起的死亡。Paeonoside 对 MC3T3-E1细胞的前成骨细胞没有细胞毒性作用，以剂量依赖性的方式显著恢复伤口区域并促进细胞迁移和促进碱性磷酸酶（ALP）染色及其活性。
TN7082	demethyldaphnoretin-7-O-glucoside	Others	Others
	demethyldaphnoretin-7-O-glucoside 是从 Daphne oleoides Schreber subsp. 中分离出来的天然产物。在土耳其传统医学中，它的地上部分已被用于治疗疟疾、风湿病和伤口愈合。
TN1132	Procyanidin A2 原花青素 A2,原花青素A2	IL Receptor; TNF; transporter; Antibacterial	Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology
	Procyanidin A2 是一种具有抗癌、抗氧化、抗菌和抗炎活性的黄酮类天然产物，存在于蔓越莓和越橘中。
TN1641	(-)-Fenchone	Others; Antioxidant; Antifungal	Microbiology/Virology; Others; oxidation-reduction
	(-)-Fenchone 是一种双环单萜类化合物，广泛分布于植物中，可从Foeniculum vulgare 和Peumus boldus 中提取。(-)-Fenchone 具有广泛的生物活性，包括抗氧化，伤口愈合，止泻，抗真菌，抗伤害感受和支气管扩张剂活性。(-)-Fenchone 是一种潜在的抗肿瘤化合物。
T3O2749	L-Leucine (S)-Leucine,Leu,L-亮氨酸,亮氨酸	mTOR	PI3K/Akt/mTOR signaling
	L-Leucine ((S)-Leucine) 是必需的支链氨基酸，能够激活 mTOR 信号通路。
T5S2347	Deoxyshikonin 去氧紫草素,Arnebin 7	Others; HIF/HIF Prolyl-Hydroxylase; Antibacterial	Chromatin/Epigenetic; Metabolism; Microbiology/Virology; Others
	Deoxyshikonin (Arnebin 7) 是从紫草中分离的天然产物，具有抗肿瘤活性，在体外具有促血管生成作用。它和没食子酸十二烷基酯在体内外均与青霉素有显着的协同抗菌活性。
TN6872	Trypsin	Protease-activated Receptor	GPCR/G Protein
	Trypsin 是一种可从鱼类分离出的丝氨酸蛋白酶，可水解赖氨酸或精氨酸羧基侧蛋白质。Trypsin 具有抗炎活性，可通过 PDCoV 的 S 糖蛋白与 pAPN 的相互作用诱导 PDCoV 感染的细胞膜融合，可激活 PAR2 和 PAR4，促进细胞增殖和分化。Trypsin 可用于促进伤口愈合和研究神经源性炎症。
T13559	Astragaloside VI	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Astragaloside VI could improve wound healing by activating the EGFR/ERK signaling pathway.
T4454	Traumatic Acid Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,愈伤酸,Trans-2-Dodecenedioic Acid	Antioxidant	oxidation-reduction
	Traumatic Acid (Dodec-2-Enedioic Acid) 是一种单不饱和二元羧酸，从菜豆中分离得到。它可减少膜磷脂的过氧化，并表现出抗氧化和对胶原生物合成的刺激作用。它可用于许多与胶原蛋白生物合成障碍和氧化应激有关的皮肤疾病的研究。
TN6495	3,4-O-dimethylcedrusin
	3′,4-O-Dimethylcedrusin can improve wound healing in vivo by stimulating the formation of fibroblasts and collagen.
TN5044	Specioside	Others	Others
	Specioside has antioxidant, analgesic, anti-dyspeptic, astringent, liver stimulating and wound healing activities. It ameliorates oxidative stress and promotes longevity in Caenorhabditis elegans.
T81322	Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside
	Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside，一种具备伤口愈合活性的化合物，可从Ophioglossum vulgatumL地上部分分离得到。
T75694	Lacto-N-neotetraose
	Lacto-N-neotetraose (LNnT) 是一种内源性代谢物 (endogenous metabolite)。Lacto-N-neotetraose 可以抑制 TNF-α 诱导的未成熟上皮细胞中的IL-8分泌。Lacto-N-neotetraose 具有抗炎活性，可提高伤口愈合能力。
T38097	Antibiotic PF 1052
	Antibiotic PF 1052 is a fungal metabolite originally isolated from Phoma.1,2 It is active against S. aureus, S. parvulus, and C. perfringens (MICs = 3.13, 0.78, and 0.39 μg/ml, respectively), among others.1 It inhibits neutrophil migration in a wound assay using zebrafish larvae expressing GFP-labeled neutrophils, reducing pseudopodia formation and inducing rounding of neutrophils.2 Antibiotic PF 1052 is selective for neutrophil migration over macrophage migration in zebrafish larvae. It also in...
T78490	Polygalacturonic acid Galacturonic acid polymer
	Polygalacturonic acid（Galacturonic acid polymer）为透明胶状物，构成细胞壁关键组分。该酸应用于制备银纳米颗粒（AgNPs），充当抗氧化剂与抗炎剂，防护细胞遭受ROS增高引起的损伤，并促进伤口愈合。Polygalacturonic acid纳米颗粒亦显示抗菌性能。

天然产物

Cat.No: T3855

Target: Estrogen Receptor/ERR, Phosphorylase

Cat.No: T3881

Target: Integrin, Akt, PERK, AMPK

Cat.No: T5S1982

Synonym: Periplocoside,杠柳毒苷

Target: Apoptosis, Others

Ginsenoside Rg4

Cat.No: TN1686

Synonym: 人参皂苷 RG4

Target: Antibacterial

4',6,7-Trimethoxyisoflavone

Cat.No: TN3016

Target: MMP

Deoxyelephantopin

Cat.No: TN1079

Target: NF-κB

Cat.No: T2827

Synonym: Asiantic acid,Dammarolic acid,积雪草酸

Target: Apoptosis, p38 MAPK, Parasite

Cat.No: T1125

Synonym: NSC 252844,Isoarnebin 4,(+)-Shikonin,紫草素,Alkanna Red,C.I. 75535,Anchusa acid

Target: TNF, NF-κB, Chloride channel, HIV Protease, PKM

(+/-)-Pinocembrin

Cat.No: TN2077

Synonym: NSC 43318,(±)-5,7-Dihydroxyflavanone

Target: GPR, Others

Cat.No: TN6926

Target: Others

demethyldaphnoretin-7-O-glucoside

Cat.No: TN7082

Target: Others

Cat.No: TN1132

Synonym: 原花青素 A2,原花青素A2

Target: IL Receptor, TNF, transporter, Antibacterial

Cat.No: TN1641

Target: Others, Antioxidant, Antifungal

Cat.No: T3O2749

Synonym: (S)-Leucine,Leu,L-亮氨酸,亮氨酸

Target: mTOR

Cat.No: T5S2347

Synonym: 去氧紫草素,Arnebin 7

Target: Others, HIF/HIF Prolyl-Hydroxylase, Antibacterial

Cat.No: TN6872

Target: Protease-activated Receptor

Astragaloside VI

Cat.No: T13559

Target: EGFR

Cat.No: T4454

Synonym: Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,愈伤酸,Trans-2-Dodecenedioic Acid

Target: Antioxidant

3,4-O-dimethylcedrusin

Cat.No: TN6495

Cat.No: TN5044

Target: Others

Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside

Cat.No: T81322

Lacto-N-neotetraose

Cat.No: T75694

Antibiotic PF 1052

Cat.No: T38097

Polygalacturonic acid

Cat.No: T78490

Synonym: Galacturonic acid polymer

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