Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sodium gualenate (Guaiazulenesulfonate sodium) 是一种桂皮烯的亲水性衍生物,具有良好的抗炎和愈伤活性,常用于十二指肠溃疡,胃溃疡和胃炎的研究。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
50 mg | ¥ 233 | 现货 | ||
100 mg | ¥ 328 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 131 | 现货 |
产品描述 | Sodium gualenate (Guaiazulenesulfonate sodium) (Guaiazulenesulfonate sodium), a hydrophilic derivative of guaiazulene (GA), is an unstable compound. It has anti-inflammatory and wound-healing effects. |
体内活性 | Sodium gualenate 经常用于治疗人类胃炎。其主要作用机制被定义为细胞保护,即保护胃黏膜[1]。 |
动物实验 | The anti-gastric ulcer activity of compounds was tested through an ethanol-induced gastric ulcer mouse model method.?Kunming mice, consisting of both males and females, each weighing about 25 g, were divided into groups of 8 at random.?The tested compounds, Omeprazole and guaiazulene derivatives which were made into suspensions using 5% CMC-Na were administered orally (0.4 mL/20 g) to the dose group, the drug reference group and the GAS-Na group respectively.?While the base control group was treated with only 5% CMC-Na.?Vehicle or test compounds were administered by the oral route once a day for five consecutive days.?After 0.5 h of the last dose, the mice were given orally 0.3 mL of anhydrous ethanol.?Half an hour after anhydrous ethanol administration, the animals were killed.?At last, the stomachs were removed and scored[1]. |
别名 | Guaiazulenesulfonate sodium, 磺酸钠 |
分子量 | 300.35 |
分子式 | C15H17NaO3S |
CAS No. | 6223-35-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (99.88 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 3.3294 mL | 16.6472 mL | 33.2945 mL | 83.2362 mL |
5 mM | 0.6659 mL | 3.3294 mL | 6.6589 mL | 16.6472 mL | |
10 mM | 0.3329 mL | 1.6647 mL | 3.3294 mL | 8.3236 mL | |
20 mM | 0.1665 mL | 0.8324 mL | 1.6647 mL | 4.1618 mL | |
50 mM | 0.0666 mL | 0.3329 mL | 0.6659 mL | 1.6647 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Sodium gualenate 6223-35-4 Others Inhibitor inhibit Guaiazulenesulfonate Guaiazulenesulfonate sodium 磺酸钠 inhibitor