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Search Results for " tone "

294

抑制剂 & 化合物

189

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T1162	Acipimox Olbemox,K-9321,阿西莫司,阿昔莫司	Others	Others
	Acipimox (K-9321) 是烟酸类似物，能够急性抑制脂解作用，抑制全身游离脂肪水平，改善胰岛素敏感性。
T18408	N-Butanoyl-L-homoserine lactone N-丁酰基-L-高丝氨酸内酯,N-Butyryl-L-homoserine lactone,C4-HSL	Antibacterial	Microbiology/Virology
	N-Butanoyl-L-homoserine lactone (C4-HSL) 是一种可降解的 ADClinker，用于抗体偶联药物的合成。它可用于抗菌生物膜，具有抗菌活性。它的适配体抑制铜绿假单胞菌生物膜的形成，可用于阻止群体感应。
T8368	Geranylacetone(Z/E) 6,10-二甲基-5,9-十一双烯-2-酮,Dihydropseudoionone	Others	Others
	Geranylacetone(Z/E) (Dihydropseudoionone) 是一种天然存在的化合物，存在于许多植物的精油中，包括迷迭香、薰衣草和茉莉花。它具有抗氧化、抗炎和抗微生物的特性。
T83654	Dilinoleyl Ketone Bis(linoleyl) ketone	Others	Others
	Dilinoleyl Ketone (Bis(linoleyl) ketone) 是一种脂质膜，是一种潜在的核酸载体。
T25944	Phenoxyacetone 苯氧乙酮,NSC-1876,NSC 1876,NSC1876	Others	Others
	Phenoxyacetone (NSC-1876) 可抑制乙酰胆碱酯酶。
T16169	N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride	Others; Proteasome; COX	Immunology/Inflammation; Neuroscience; Others; Proteases/Proteasome; Ubiquitination
	N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride (N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride) 是胰蛋白酶样蛋白酶的抑制剂。 N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride 对 IFN-γ 活性具有抑制作用。
T25048	Algestone acetophenide Neolutin,苯甲孕酮	Others	Others
	Algestone acetophenide (Neolutin) 是用于发情同步的孕酮，已被评估为与庚酸雌二醇联合使用的注射避孕药。它在治疗上也用作局部抗炎药，并在治疗痤疮时局部应用。
T8340	Quinocetone	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Quinocetone 是一种合成的强效抗菌剂，可用于提高饲料用动物饲料效率和控制痢疾。
T11563	Histone Acetyltransferase Inhibitor II	Epigenetic Reader Domain; Histone Acetyltransferase	Chromatin/Epigenetic
	Histone Acetyltransferase Inhibitor II 是一种选择性的细胞渗透性 p300 组蛋白乙酰转移酶抑制剂，IC50值为 5 µM。它在哺乳动物细胞中具有抗乙酰化酶活性，可用于癌症研究。
T41319	D-Saccharic acid 1,4-lactone hydrate	Others	Others
	D-Saccharic acid 1,4-lactone hydrate 是β-葡萄糖醛酸酶的有效抑制剂（IC50=48.4 μM），可用作标准药物。D-Saccharic acid 1,4-lactone hydrate 显示出抗癌、解毒和抗氧化的活性性。
T20569	Dicyclohexyl ketone Cyclohexane ketone,二环己基甲酮,Ketone, dicyclohexyl	Others	Others
	Dicyclohexyl ketone (Cyclohexane ketone) 是一种硫化促进剂。
T5523	Imidazole ketone erastin IKE	Ferroptosis	Apoptosis
	Imidazole ketone erastin (IKE) 是一种铁死亡诱导剂，对 system Xc-胱氨酸/谷氨酸转运蛋白具有抑制作用。Imidazole ketone erastin 具有抗肿瘤活性，可以诱导谷胱甘肽耗竭和脂质过氧化。
T38766L	Histone H3 (1-35) acetate	Others	Others
	Histone H3 (1-35) acetate 是组蛋白 H3 的 35 个残基肽。组蛋白 H3 是一种重要的蛋白质，在基因的动态和长期调控中发挥作用。
T77691	Cyclopentyl phenyl ketone Benzoylcyclopentane	Others	Others
	Cyclopentyl phenyl ketone (Benzoylcyclopentane) 可用于预防和治疗创伤应激症。
T20460	Piperonyl acetone 胡椒基丙酮,NSC405365,NSC 405365,NSC-405365	Others	Others
	Piperonyl acetone (NSC-405365) 是一种食品添加剂，用于食用调味料。
T16226	N-(Ketocaproyl)-DL-homoserine lactone N-(Ketocaproyl)-D,L-homoserine lactone,N-(3-氧代己酰)-DL-高丝氨酸内酯	Antibacterial	Microbiology/Virology
	N-(Ketocaproyl)-DL-homoserine lactone 是群体感应自动诱导剂。它是 LuxR 的天然配体。
T22374	N-(beta-Ketocaproyl)-L-hoMoserine lactone N-3-氧-己酰高丝氨酸内酯,N-(β-Ketocaproyl)-L-hoMoserine lactone,N-(Ketocaproyl)-L-homoserine lactone,N-(β-Ketocaproyl)-L-hoMoserine lactone	Others	Others
	N-(beta-Ketocaproyl)-L-hoMoserine lactone (N-(Ketocaproyl)-L-homoserine lactone) 是群体调节感应的成分之一。
T37746	N-phenylacetyl-L-Homoserine lactone	Others	Others
	N-phenylacetyl-L-Homoserine lactone 可衰减病原体鲍曼不动杆菌的群体感应，可用于研究细菌感染。
T20568	Cyclohexylphenylketone 环己基苯基甲酮,AI3-11009,Cyclohexyl phenyl ketone,AI311009,AI3 11009	Others	Others
	Cyclohexylphenylketone (AI311009) 可用作光引发剂，用于分光光度法测定二苯甲酮。
T1258	Nabumetone BRL14777,萘丁美酮	COX; Glutathione Peroxidase	Immunology/Inflammation; Metabolism; Neuroscience
	Nabumetone (BRL14777) 是一种非甾体抗炎药，是选择性COX-2抑制剂，其活性代谢物 6MNA 可抑制环加氧酶 I 和 II。
T1148	Menbutone 孟布酮,Naftobil,Genabilic acid,Genabilin	Others	Others
	Menbutone (Genabilin) 是一种利胆剂，是氧代丁酸衍生物。
T0476	Spironolactone 安体舒通,螺内酯,SC9420,Abbolactone	Glucocorticoid Receptor; Androgen Receptor; Autophagy	Autophagy; Endocrinology/Hormones
	Spironolactone (SC9420) 是一种可口服的醛固酮盐皮质激素受体拮抗剂，IC50值为 24 nM。它也是雄激素受体拮抗剂，促进足细胞自噬，IC50值为 77 nM。
T14219	Aminaftone Aminaphthone	Endothelin Receptor	GPCR/G Protein
	Aminaftone 是 4-氨基苯甲酸的衍生物，可抑制内皮素-1 (ET-1) 的产生，可用于研究高血压和系统硬化症。
T12490	Pitavastatin lactone	Others	Others
	Pitavastatin lactone 是 Pitavastatin 在人体中的主要代谢产物。Pitavastatin 是 HMG-CoA 还原酶竞争性抑制剂。
T1588	Idramantone 5-Hydroxy-2-adamantanone,伊决孟酮,Kemantane,伊屈孟酮 (INN)	Others	Others
	Idramantone (Kemantane) 是一种免疫激活剂，是 Adamantane 衍生物。
T37739	N-decanoyl-L-Homoserine lactone C10-HSL,N-decanoyl-L-Homoserine lactone	Reactive Oxygen Species; Antibacterial	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	N-decanoyl-L-Homoserine lactone (C10-HSL) 是一种由克雷莫里色假单胞菌菌株 ND07产生的 N-acyl-homoserine lactone (AHL)。N-decanoyl-L-homoserine lactone 可抑制拟南芥的主根生长。N-decanoyl-L-homoserine lactone 处理可引起拟南芥根胞质游离 Ca2+ 和活性氧 (ROS) 浓度短暂和和立即升高，增加丝裂原激活蛋白激酶 6 (MPK6) 的活性，并促使一氧化氮 (NO) 的产生。
T37744	N-octanoyl-L-Homoserine lactone C8-HSL,N-octanoyl-L-Homoserine lactone,OHL	Antibacterial	Microbiology/Virology
	N-octanoyl-L-Homoserine lactone (C8-HSL) 是一种具有扩散性的外源性鼠疫耶尔森菌群体感应分子，可调节LcrV毒力因子，通过参与群体感应控制基因表达，影响细胞代谢。N-octanoyl-L-Homoserine lactone 是用于研究囊性纤维的感染。
T1102	Mifepristone C-1073,RU486,RU 38486,米非司酮	Glucocorticoid Receptor; Estrogen/progestogen Receptor; Progesterone Receptor; NO Synthase; Autophagy	Autophagy; Endocrinology/Hormones; Immunology/Inflammation; Others
	Mifepristone (C-1073) 是一种黄体酮受体和糖皮质激素受体拮抗剂，在体外实验中的 IC50值分别为 0.2 nM 和 2.6 nM。
T39308	Boc-Asp(OMe)-fluoromethyl ketone Boc-Asp(OMe)-fluoromethyl ketone,Boc-Asp(OMe)-FMK	Caspase	Apoptosis; Proteases/Proteasome
	Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) 是广谱的 caspase 抑制剂，可抑制 Fas 介导的吞噬作用和氧化破裂抑制，但对 IL-8 的趋化活性无影响。
T0721	Piroctone olamine Piroctone ethanolamine,羟吡酮,吡罗克酮乙醇胺盐	Antibiotic; Antifungal	Microbiology/Virology
	Piroctone olamine (Piroctone ethanolamine) 是一种吡啶衍生物，可用于治疗真菌感染。
T23477	tris(dibenzylideneacetone)dipalladium Tris DBA,三(二亚苄基丙酮)二钯	Others	Others
	tris(dibenzylideneacetone)dipalladium (Tris DBA) 是一种 N-myristoyltransferase-1 (NMT-1) 抑制剂。
T13965	Watermelon ketone 7-Methyl-2H-1,5-benzodioxepin-3(4H)-one,西瓜酮	Others	Others
	Watermelon ketone (7-Methyl-2H-1,5-benzodioxepin-3(4H)-one) 是一种具有特殊气味的香料，已广泛应用于香水行业。
TP1597L	Secretoneurin, rat acetate Secretoneurin, rat acetate(149146-12-3 Free base)	Others	Others
	Secretoneurin, rat acetate 是一种 33 个氨基酸的多肽，由分泌粒蛋白 II (SgII) 的蛋白水解加工产生。它在体内和体外诱导大鼠纹状体中的多巴胺释放，它对单核细胞和嗜酸性粒细胞有很强的趋化作用，但对粒细胞没有。
T41287	N-3-Oxo-octanoyl-L-homoserine lactone	Others	Others
	N-3-Oxo-octanoyl-L-homoserine lactone 是一种群体感应信号分子，是农杆菌自诱导剂。
T13789	N-dodecanoyl-L-Homoserine lactone C12-HSL,十二烷酰-L-高丝氨酸内酯	Others	Others
	N-dodecanoyl-L-Homoserine lactone (C12-HSL) 是群体感应 (QS) 信号分子的一种。它适配体可用于阻止群体感应，并能够阻碍铜绿假单胞菌 (Pseudomonas aeruginosa) 生物膜的形成。
T14342	Atorvastatin lactone	HMG-CoA Reductase	Metabolism
	Atorvastatin lactone 是一种 Atorvastatin 的前药。其中 Atorvastatin 是口服具有活力的 3- 羟基 -3- 甲基戊二酰辅酶 A 还原酶抑制剂。
T37742	N-hexanoyl-DL-Homoserine lactone
	N-hexanoyl-DL-Homoserine lactone is a bacterial quorum sensing signaling molecule that is produced by mammalian pathogenic and rhizosphere-colonizing bacteria.1,2,3Application of N-hexanoyl-DL-homoserine lactone (60 μM) to tomato leaves suppresses the development of lesions induced by the plant pathogenic fungiB. cinerea.2It also increases root length and shoot diameter when applied toA. thalianaseedlings in a hydroponic growth system at a concentration of 10 μM.3
T21335	Fluorogestone acetate Flurogestone Acetate Flugestone Acetate Fluorogesterone Acetate SC9880,氟孕酮醋酸酯	Others	Others
	Fluorogestone acetate (Flurogestone Acetate Flugestone Acetate Fluorogesterone Acetate SC9880) 显示出高效力且活性持续时间短，并且在生理上与孕酮相似。 FGA 的效力大约是黄体酮的 20-25 倍。
T20466	Keto-pantoyllactone 二氢-4,4-二甲基-2,3-呋喃二酮,Keto pantoyllactone,Ketopantoyllactone,Dihydro-4,4-dimethyl-2,3-furandione	Others	Others
	Keto-pantoyllactone (Dihydro-4,4-dimethyl-2,3-furandione) 通过烟酰胺腺嘌呤二核苷酸磷酸的酮泛酰内酯依赖性氧化来测定。
T22375	N-hexanoyl-L-Homoserine lactone 己酰-L-高丝氨酸内酯,C6-HSL	Others; Antibacterial	Microbiology/Virology; Others
	N-hexanoyl-L-Homoserine lactone (C6-HSL) 是一种可扩散信号分子，参与控制基因表达、影响细胞代谢和群体感应。
T5323	Toloxatone 托洛沙酮,MD 69276	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Toloxatone (MD 69276) 是可逆的单胺氧化酶 A (MAOA) 抑制剂，是一种抗抑郁剂。
T19764	Trepibutone AA-149,Colibil, Supacal,AA149,AA 149,曲匹布通	Others	Others
	Trepibutone (AA-149) 是一种酸性药物，具有不依赖于 pH 值的释放能力。
T6307	Lubiprostone 芦比前列酮,SPI-0211,RU-0211,鲁比前列酮	Chloride channel	Membrane transporter/Ion channel
	Lubiprostone (RU-0211) 是一种 ClC-2 氯化物通道的激活剂，用于治疗特发性慢性便秘。
T11044	Dihydromunduletone DHM	GPR	Endocrinology/Hormones; GPCR/G Protein
	Dihydromunduletone (DHM) 是一种粘附 G 蛋白偶联受体 (aGPCR）拮抗剂，可做一种化学探针，对具有相似拴系激动剂的 GPR56 和 GPR114/ADGRG5 有抑制作用。
T77560	Histone acetyltransferase p300 Inhibitor 4c	Carbonic Anhydrase; AChE	Metabolism; Neuroscience
	Histone acetyltransferase p300 Inhibitor 4c 是2-氨基噻唑衍生物，Histone acetyltransferase p300 Inhibitor 4c 对 hCA I 、hCA II、AChE 和 BChE 具有抑制作用，Ki 值为 0.008 ± 0.001 、 0.124 ± 0.017、0.129 ± 0.030 和 0.083 ± 0.041 μM。
T21132	Aglepristone
	Aglepristone is a synthetic steroidal antiprogestogen related to mifepristone and possesses some antiglucocorticoid activity. It is specifically used as an abortifacient in pregnant animals.
T35590	Graphislactone A
	Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M. olivacea. It exhibits dose-dependent scavenging activity against DPPH radicals and metal ion-dependent hydroxyl radicals in vitro. Graphislactone A reduces peroxidation of human LDL and slows peroxidation of linoleic acid by 4.4-fold. It also inhibits acetylcholinesterase (AChE) with an IC50 value of 27 μM.
T36980	Histone H3K27Me1 (23-34) (trifluoroacetate salt) Histone H3K27Me1 (23-34) (trifluoroacetate salt)
	Histone H3K27Me1 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences. Monomethylation of histone H3 at lysine 27 is associated with actively transcribed genes and positively correlates with H3K36 trimethylation. Levels of H3K27Me1 are increased in tumor tissue isolated from patients with metastatic hormone-na ve and castration-resistant prostate cancer. Histone H3K27Me1 (23-34) has been used in epitope mapping of ...
T64592	Histone H3 Antibody #9715R
	Histone H3 Antibody #9715R 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64592。
T124145	Carinatone
	Carinatone 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124145，CAS号为 82843-81-0。

化合物

Cat.No: T1162

Synonym: Olbemox,K-9321,阿西莫司,阿昔莫司

Target: Others

N-Butanoyl-L-homoserine lactone

Cat.No: T18408

Synonym: N-丁酰基-L-高丝氨酸内酯,N-Butyryl-L-homoserine lactone,C4-HSL

Target: Antibacterial

Geranylacetone(Z/E)

Cat.No: T8368

Synonym: 6,10-二甲基-5,9-十一双烯-2-酮,Dihydropseudoionone

Target: Others

Dilinoleyl Ketone

Cat.No: T83654

Synonym: Bis(linoleyl) ketone

Target: Others

Cat.No: T25944

Synonym: 苯氧乙酮,NSC-1876,NSC 1876,NSC1876

Target: Others

N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride

Cat.No: T16169

Synonym: N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride

Target: Others, Proteasome, COX

Algestone acetophenide

Cat.No: T25048

Synonym: Neolutin,苯甲孕酮

Target: Others

Cat.No: T8340

Target: Others, Antibacterial, Antibiotic

Histone Acetyltransferase Inhibitor II

Cat.No: T11563

Target: Epigenetic Reader Domain, Histone Acetyltransferase

D-Saccharic acid 1,4-lactone hydrate

Cat.No: T41319

Target: Others

Dicyclohexyl ketone

Cat.No: T20569

Synonym: Cyclohexane ketone,二环己基甲酮,Ketone, dicyclohexyl

Target: Others

Imidazole ketone erastin

Cat.No: T5523

Synonym: IKE

Target: Ferroptosis

Histone H3 (1-35) acetate

Cat.No: T38766L

Target: Others

Cyclopentyl phenyl ketone

Cat.No: T77691

Synonym: Benzoylcyclopentane

Target: Others

Piperonyl acetone

Cat.No: T20460

Synonym: 胡椒基丙酮,NSC405365,NSC 405365,NSC-405365

Target: Others

N-(Ketocaproyl)-DL-homoserine lactone

Cat.No: T16226

Synonym: N-(Ketocaproyl)-D,L-homoserine lactone,N-(3-氧代己酰)-DL-高丝氨酸内酯

Target: Antibacterial

N-(beta-Ketocaproyl)-L-hoMoserine lactone

Cat.No: T22374

Synonym: N-3-氧-己酰高丝氨酸内酯,N-(β-Ketocaproyl)-L-hoMoserine lactone,N-(Ketocaproyl)-L-homoserine lactone,N-(β-Ketocaproyl)-L-hoMoserine lactone

Target: Others

N-phenylacetyl-L-Homoserine lactone

Cat.No: T37746

Target: Others

Cyclohexylphenylketone

Cat.No: T20568

Synonym: 环己基苯基甲酮,AI3-11009,Cyclohexyl phenyl ketone,AI311009,AI3 11009

Target: Others

Cat.No: T1258

Synonym: BRL14777,萘丁美酮

Target: COX, Glutathione Peroxidase

Cat.No: T1148

Synonym: 孟布酮,Naftobil,Genabilic acid,Genabilin

Target: Others

Cat.No: T0476

Synonym: 安体舒通,螺内酯,SC9420,Abbolactone

Target: Glucocorticoid Receptor, Androgen Receptor, Autophagy

Cat.No: T14219

Synonym: Aminaphthone

Target: Endothelin Receptor

Pitavastatin lactone

Cat.No: T12490

Target: Others

Cat.No: T1588

Synonym: 5-Hydroxy-2-adamantanone,伊决孟酮,Kemantane,伊屈孟酮 (INN)

Target: Others

N-decanoyl-L-Homoserine lactone

Cat.No: T37739

Synonym: C10-HSL,N-decanoyl-L-Homoserine lactone

Target: Reactive Oxygen Species, Antibacterial

N-octanoyl-L-Homoserine lactone

Cat.No: T37744

Synonym: C8-HSL,N-octanoyl-L-Homoserine lactone,OHL

Target: Antibacterial

Cat.No: T1102

Synonym: C-1073,RU486,RU 38486,米非司酮

Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, NO Synthase, Autophagy

Boc-Asp(OMe)-fluoromethyl ketone

Cat.No: T39308

Synonym: Boc-Asp(OMe)-fluoromethyl ketone,Boc-Asp(OMe)-FMK

Target: Caspase

Piroctone olamine

Cat.No: T0721

Synonym: Piroctone ethanolamine,羟吡酮,吡罗克酮乙醇胺盐

Target: Antibiotic, Antifungal

tris(dibenzylideneacetone)dipalladium

Cat.No: T23477

Synonym: Tris DBA,三(二亚苄基丙酮)二钯

Target: Others

Watermelon ketone

Cat.No: T13965

Synonym: 7-Methyl-2H-1,5-benzodioxepin-3(4H)-one,西瓜酮

Target: Others

Secretoneurin, rat acetate

Cat.No: TP1597L

Synonym: Secretoneurin, rat acetate(149146-12-3 Free base)

Target: Others

N-3-Oxo-octanoyl-L-homoserine lactone

Cat.No: T41287

Target: Others

N-dodecanoyl-L-Homoserine lactone

Cat.No: T13789

Synonym: C12-HSL,十二烷酰-L-高丝氨酸内酯

Target: Others

Atorvastatin lactone

Cat.No: T14342

Target: HMG-CoA Reductase

N-hexanoyl-DL-Homoserine lactone

Cat.No: T37742

Fluorogestone acetate

Cat.No: T21335

Synonym: Flurogestone Acetate Flugestone Acetate Fluorogesterone Acetate SC9880,氟孕酮醋酸酯

Target: Others

Keto-pantoyllactone

Cat.No: T20466

Synonym: 二氢-4,4-二甲基-2,3-呋喃二酮,Keto pantoyllactone,Ketopantoyllactone,Dihydro-4,4-dimethyl-2,3-furandione

Target: Others

N-hexanoyl-L-Homoserine lactone

Cat.No: T22375

Synonym: 己酰-L-高丝氨酸内酯,C6-HSL

Target: Others, Antibacterial

Cat.No: T5323

Synonym: 托洛沙酮,MD 69276

Target: MAO, Monoamine Oxidase

Cat.No: T19764

Synonym: AA-149,Colibil, Supacal,AA149,AA 149,曲匹布通

Target: Others

Cat.No: T6307

Synonym: 芦比前列酮,SPI-0211,RU-0211,鲁比前列酮

Target: Chloride channel

Dihydromunduletone

Cat.No: T11044

Synonym: DHM

Target: GPR

Histone acetyltransferase p300 Inhibitor 4c

Cat.No: T77560

Target: Carbonic Anhydrase, AChE

Cat.No: T21132

Graphislactone A

Cat.No: T35590

Histone H3K27Me1 (23-34) (trifluoroacetate salt)

Cat.No: T36980

Synonym: Histone H3K27Me1 (23-34) (trifluoroacetate salt)

Histone H3 Antibody #9715R

Cat.No: T64592

Cat.No: T124145

Cat. No.	Product Name	Target	Signaling Pathways
TN6832	Sulcatone 6-甲基-5-庚烯-2-酮,6-methylhept-5-en-2-one,6-Methyl-5-hepten-2-one	Endogenous Metabolite	Metabolism
	Sulcatone (6-Methyl-5-hepten-2-one) 是内源性代谢产物的一种。
T5968	DL-Homocysteine thiolactone hydrochloride DL-Homocysteinethiolactone hydrochloride,DL-高半胱氨酸硫内酯盐酸盐	Endogenous Metabolite	Metabolism
	DL-Homocysteine thiolactone hydrochloride (DL-Homocysteinethiolactone hydrochloride) 是具有根生长抑制特性的环状氨基酸衍生物。
T41122	1,3-Dihydroxyacetone	Endogenous Metabolite	Metabolism
	1,3-Dihydroxyacetone 是防晒美黑护肤制剂的主要活性成分，是合成各种精细化学品的重要前体，也是一种食品添加剂，可通过在 Gluconobacter oxydans 上进行微生物发酵实现工业规模生产。1,3-Dihydroxyacetone 具有提高cAMP 水平的能力。
T7995	α-Angelica lactone α-当归内酯,当归内酯,Alpha-Angelica Lactone	Others; GST	Others; oxidation-reduction
	α-Angelica lactone 是一种乙烯基亲核试剂，也是一种天然存在的抗癌剂。它可以得到手性的 δ-氨基 γ，γ-二取代丁烯醇内酯羰基衍生物，并在 γ-碳上表现出亲电子俘获。它通过选择性增强谷胱甘肽-S-硫转移酶 (GST) 和 UDP-葡糖苷转移酶 (UGT) 解毒酶发挥强大的化学保护作用。
T2829	Isoalantolactone (+)-Isoalantolactone,Isohelenin,异土木香内酯	Apoptosis; Endogenous Metabolite; Antibacterial; Autophagy	Apoptosis; Autophagy; Metabolism; Microbiology/Virology
	Isoalantolactone (Isohelenin) 是一种可用作细胞凋亡诱导剂的烷化剂。
T10941	D-Ribonolactone D-(+)-核糖酸-1,4-内酯,D-核糖内酯	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	D-Ribonolactone 是一种大肠杆菌 β-半乳糖苷酶的抑制剂，Ki 为 26 mM。它也一种糖内酯。
T12045	(-)-Hydroxycitric acid lactone 藤黄内酯,Garcinia lactone	ATP Citrate Lyase	Metabolism
	(-)-Hydroxycitric acid lactone (Garcinia lactone) 是一种有效的 ATP-柠檬酸裂解酶抑制剂，能够催化柠檬酸盐线粒体外裂解为草酰乙酸和乙酰辅酶 A，限制了脂肪酸合成所需乙酰辅酶 A 单位的可用性。它是一种减肥药，是一种广受欢迎的减肥食品补充剂。
T25192	Butyrolactone I Olomoucin,丁酸内酯I	CDK	Cell Cycle/Checkpoint
	Butyrolactone I (Olomoucin) 是 CDK 和 cdc2 激酶家族的 ATP 竞争性抑制剂。 Butyrolactone I 在非小细胞肺、小细胞肺和前列腺癌细胞系中显示出抗肿瘤作用。
T9327	ω-Pentadecalactone Cyclopentadecanolide,ω-十五内酯,Oxacyclohexadecan-2-one,Exaltolide,Pentadecanolide	Others	Others
	ω-Pentadecalactone (Exaltolide) 是香料成分，是一种香味结构组大环内酯和丙交酯衍生物的成员。
TN1204	2,3-Dehydrokievitone 2,3-脱氢维酮	Antifungal	Microbiology/Virology
	2,3-Dehydrokievitone 是一种从刺桐属植物 Erythrina sacleuxii 中提取的一种异黄酮，具有抗菌活性，可通过降低α-溶血素表达来对抗耐甲氧西林金黄色葡萄球菌感染。
T40815	δ-Decalactone	Others	Others
	δ-Decalactone 存在于脱脂奶粉和水果中，具有甜味。
TN1143	1-O-Acetyl britannilactone	NF-κB; COX	Immunology/Inflammation; Neuroscience; NF-κB
	1-O-Acetyl britannilactone shows antifungal, and anti-cancer activities, it suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR-Src-FAK signaling.
TQ0118	Britannilactone Desacetylinulicin,旋覆花内酯	Others	Others
	Britannilactone, extracted from the dried flower of Inula britannica L, significantly reduces melanin production in a dose-dependent manner (IC50: 15.5 uM).
T4719	1,4-D-Gulonolactone D-Gulonic acid γ-lactone,D-(-)-古洛糖酸-1,4-内酯	Others; Endogenous Metabolite	Metabolism; Others
	1,4-D-Gulonolactone (D-Gulonic acid γ-lactone) (也称为还原性抗坏血酸，RAA) 是 L-gulono-1,4-lactone oxidoreductase (EC 1.1.3.8)的底物，催化植物和动物中l -抗坏血酸(维生素C)生物合成的最后一步。enzyme L-Gulono-1,4-lactone oxidase 在容易患坏血病、缺乏维生素c的动物(如人类)中缺失。1,4-D-Gulonolactone 存在于人体血液中，并被用作比较运动引起的氧化应激变化的标志物之一。
T5S1897	Linderalactone	Apoptosis; Others; JAK	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Others; Stem Cells
	Linderalactone 是从乌药中分离出来的一种倍半萜烯内酯，通过调节凋亡相关蛋白的表达和抑制 JAK/STAT 信号通路来抑制癌细胞生长。它以 IC50值为 15 µM 来抑制肺癌 A-549 细胞的增殖。
TN1637	Eurycomalactone	Anti-infection; NF-κB	Microbiology/Virology; NF-κB
	Eurycomalactone 是一种NF-κB 抑制剂，IC50=0.5 μM，是一种天然产物。它可抑制蛋白合成，降低 cyclin D1 蛋白水平，但对 TNFα 诱导的 IκBα 降解或 IKKα/β 和 IκBα 的磷酸化水平没有作用。
T5728	OsMundacetone 4-(3,4-Dihydroxyphenyl)-3-buten-2-one	Apoptosis; Reactive Oxygen Species	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
	OsMundacetone (4-(3,4-Dihydroxyphenyl)-3-buten-2-one) 是从白桦茸中分离出的一种天然产物，具有抗凋亡作用。它具有DPPH 清除活性，保护神经细胞免受氧化应激，可研究神经退行性疾病。
T2896	Alantolactone 土木香内酯,helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,土木香脑,Inula camphor	Apoptosis; STAT; TGF-beta/Smad	Apoptosis; JAK/STAT signaling; Stem Cells
	Alantolactone (Inula camphor) 是一种STAT3的选择性抑制剂，可诱导癌症相关的凋亡，具有抗肿瘤活性。
TCS1554	trans-Benzylideneacetone 反式苯亚甲基丙酮,Acetocinnamone,亚苄基丙酮	Phospholipase	Metabolism
	trans-Benzylideneacetone (Acetocinnamone) 是一种革兰氏阴性致病性线虫细菌嗜线虫(Xenorhabdus nematophila) 的代谢产物，是一种针对磷脂酶 A2 (PLA2) 的酶抑制剂，也是一种免疫抑制剂。
T8249	Hexahydrofarnesyl acetone 植酮,Phytone	Others; Antibacterial	Microbiology/Virology; Others
	Hexahydrofarnesyl acetone (Phytone) 是从Launaea mucronata 中分离得到的倍半萜，具有抗菌和抗炎活性，可研究缓解疼痛。
T2833	Dehydrocostus Lactone Epiligulyl oxide,去氢木香内酯,(-)-Dehydrocostus lactone,去氢木香烃内酯	IκB/IKK	NF-κB
	Dehydrocostus Lactone ((-)-Dehydrocostus lactone) 是一种倍半萜内酯，从云木香中分离得到。
Fr12339	Anisylacetone 茴香基丙酮	Others	Others
	Anisylacetone (Anisylacetone) 是一种有效的雄瓜蝇诱饵。
T8085	(-)-Corey lactone diol 科立内脂二醇,Corey Lactone Diol	Others	Others
	(-)-Corey lactone diol 是 corey aldehyde 的还原形式，也是化学合成中的砌块。
TN7021	Ent-toddalolactone	Others	Others
	Ent-toddalolactone 是一种天然化合物，属于香豆素类，来源于两面针，具有抗炎、抗癌活性。
T10383	Asatone	NF-κB	NF-κB
	Asatone 是一种从细辛中分离到的活性成分，通过活化 NF-κB 及下调 p-MAPK (ERK，JNK 和 p38) 通路起作用，具有抗炎作用。
TN6700	gamma-Nonanolactone	Others	Others
	gamma-Nonanolactone 是蒸小麦的香气成分。
T1353	DL-Mevalonolactone 甲瓦龙酸内酯,Mevalonolactone	Others; Endogenous Metabolite	Metabolism; Others
	DL-Mevalonolactone (Mevalonolactone)，一种人内源性代谢物，是甲羟戊酸的 δ-lactone 形式，甲羟戊酸途径的一个前体。它能够降低大脑中线粒体膜电位(∆Ψm)，Ca2+的保留能力和 NAD (P) H 的含量 , 而且还诱导线粒体肿胀。
T8078	Gamma-decalactone Decan-4-olide,γ-Decalactone,丙位癸内酯	Others	Others
	Gamma-decalactone (Decan-4-olide) 是一种具有果味桃子味的食品添加剂。蓖麻油酸 (12-羟基-十八烷基-9-烯酸) 常作为 γ-Decalactone 的生产过程中的底物。
TCS1709	BENZYLACETONE 苄基丙酮,4-Phenylbutan-2-one,Methyl 2-phenylethyl ketone,4-Phenyl-2-butanone	Tyrosinase	Proteases/Proteasome
	Benzylacetone (4-Phenyl-2-butanone) 是一种从沉香木中提取的芳香族化合物。它具有增强食欲和减少运动的作用。它具有较强且可逆的抗蘑菇酪氨酸酶作用，对单酚酶和双酚酶作用的IC50值分别为 2.8 mM 和 0.6 mM。
T4S0592	Toddalolactone (+)-Toddalolactone,飞龙掌血内酯,毛两面针素	PAI-1	Metabolism
	Toddalolactone ((+)-Toddalolactone) 是一种Toddalia asiatica 的主要成分，能够抑制重组人纤溶酶原激活物抑制物-1(PAI-1)的活性， IC50=37.31 μM。
TN6744	Undecanoic gamma-lactone	Others	Others
	Undecanoic gamma-lactone 是一种天然产物。
TN6993	Benzylideneacetone Benzalacetone	Phospholipase; Endogenous Metabolite	Metabolism
	Benzylideneacetone 是由昆虫致病细菌 Xenorhabdus nematophila 产生的单萜类化合物，是磷脂酶A2（PLA2）抑制剂，对类花生酸生物合成具有抑制作用，可增强小菜蛾木霉菌的杆状病毒致病性。
T3384	Wedelolactone 蟛蜞菊内酯,IKK Inhibitor II	Apoptosis; NF-κB; Lipoxygenase; Caspase	Apoptosis; Metabolism; NF-κB; Proteases/Proteasome
	Wedelolactone (IKK Inhibitor II) 是来自旱莲草的一种天然产物，通过阻断 IκBα 的磷酸化和降解来抑制细胞中 NF-κB 介导的基因转录，具有抗癌，抗炎和抗氧化活性。
T11680	Isoasatone A	P450	Metabolism
	Isoasatone A 是一种具有抗虫作用的天然产物，分离自Heterotropa takaoiM。它作用于细胞色素 P450 单加氧酶和谷胱甘肽转移酶，产生抗S. litura 作用。
TN7168	Farnesylacetone (5E,9E)-6,10,14-Trimethylpentadeca-5,9,13-trien-2-one,法尼基丙酮,Farnesyl acetone,E,E-farnesylacetone	Others	Others
	Farnesylacetone ((5E,9E)-6,10,14-Trimethylpentadeca-5,9,13-trien-2-one) 是一种海洋来源的天然产物，存在于Sargassum micracanthum。
T2S0633	Raspberry ketone Oxyphenalon,Rasketone,Aloenin,4-(4-Hydroxyphenyl)-2-butanone,p-Hydroxybenzyl acetone,Frambinone,覆盆子酮	PPAR	DNA Damage/DNA Repair; Metabolism
	Raspberry ketone (p-Hydroxybenzyl acetone) 是覆盆子中主要的芳香族天然产物，主要用作化妆品的香料和食品增味剂，也可作 PPAR-α激动剂。
T0933	D-(+)-Glucono-1,5-lactone Gluconic acid lactone,Delta-Gluconolactone,Gluconolactone,葡萄糖酸内酯	Others; Reactive Oxygen Species; Endogenous Metabolite	Immunology/Inflammation; Metabolism; NF-κB; Others
	D-(+)-Glucono-1,5-lactone (Gluconolactone) 是聚羟基酸，可螯合金属离子，具有保湿、抗氧化特性。
T5742	Isodemethylwedelolactone 异去甲蟛蜞菊内酯,Isodemethylwedelolacton	Others	Others
	Isodemethylwedelolactone (Isodemethylwedelolacton) 是一种促凝剂，也是溶血性成分，分离自 Eclipta alba。
T8098	γ-Hexalactone γ-caprolactone,gamma-己内酯,γ-己内酯	Others	Others
	γ-Hexalactone (γ-caprolactone) 是一种存在成熟水果中的 gamma 内酯。它会导致 DNA 损伤，可用作对氧磷酶 1 的底物 (PON1)。
T4S0867	Pogostone DHELWANGIN,广藿香酮	Apoptosis; Antibacterial; Autophagy	Apoptosis; Autophagy; Microbiology/Virology
	Pogostone (DHELWANGIN) 是从薄荷中分离出，对革兰氏阴性菌、革兰氏阳性菌、大肠埃希菌等具有强效抗菌、抗真菌活性。它诱导细胞凋亡和自噬。
T3S0195	Nootkatone 诺卡酮,努特卡酮,诺卡酮	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	Nootkatone 是一种神经保护剂，来自于Alpiniae OxyphyllaeFructus ，具有抗氧化和抗炎活性。它能够改善脂多糖诱导的阿尔茨海默氏病小鼠模型的认知障碍。
T8244	Raspberry ketone glucoside 覆盆子酮葡糖苷,树莓苷，覆盆子酮葡萄糖甙	Others	Others
	Raspberry ketone glucoside 是一种山莓果实中的天然产物。它能够抑制黑色素的合成。
T20345	Benzoylacetone AI3 10572,苯甲酰丙酮,AI3-10572,AI310572	Antibacterial	Microbiology/Virology
	Benzoylacetone (AI3 10572) 具有抗菌活性。
TN2539	1beta-Hydroxyalantolactone	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	1beta-Hydroxyalantolactone 是从药用植物大英花的花头中分离出的小分子化合物，可抑制细胞中TNF-α、IL-17、IFN-γ的表达，促进TNF-α、IFN-γ、IL-17的分泌，可防治类风湿性关节炎。
T5578	L-Gulono-1,4-lactone	Others; Endogenous Metabolite	Metabolism; Others
	L-Gulono-1,4-lactone 是一种 L-古洛糖酸-γ-内酯氧化还原酶的作用底物，该酶能促进维生素 C 合成的末步。它是动物、植物和一些原生生物中维生素 C 的直接前体。
T5654	Musk ketone	Others	Others
	Musk ketone 可诱导癌细胞生长抑制和凋亡。它增加谷胱甘肽 S-转移酶的活性，因此可能被证明是有用的癌症化学保护剂。
TN6718	Dehydrocostuslactone	Others	Others
	Dehydrocostuslactone 是一种从奥克兰提取的天然产物。它具有广泛的生物作用，包括抗炎、抗癌、抗病毒、抗菌、抗真菌、抗氧化、抗糖尿病、抗溃疡和驱虫活性。
T0434	D-Glucuronic acid lactone Glucuronolactone,D-Glucurone,Dicurone,葡醛内酯	Others; Endogenous Metabolite	Metabolism; Others
	D-Glucuronic acid lactone (Dicurone) 是内源性代谢产物的一种。
T4S0176	Alnustone (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one,桤木酮	Others	Others
	Alnustone ((4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one) 是一种非酚双苯庚烷类化合物，在草药和香料中发现，是姜黄的成分之一，具有抗吐、抗炎作用。
T19281L	Dihydroxyacetone phosphate hemimagnesium salt hydrate Dihydroxyacetone phosphate hemimagnesium salt hydrate(57-04-5 free base)	Others	Others
	Dihydroxyacetone phosphate hemimagnesium salt hydrate 也称为磷酸二羟基丙酮或 3-羟基-2-氧代丙基磷酸。 Dihydroxyacetone phosphate hemimagnesium salt hydrate 存在于从细菌到人类的所有生物中。在人类体内， Dihydroxyacetone phosphate hemimagnesium salt hydrate参与许多酶促反应。 Dihydroxyacetone phosphate hemimagnesium salt hydrate 已被研究用于治疗淋巴瘤、大细胞淋巴瘤、弥漫性淋巴瘤。
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天然产物

Cat.No: TN6832

Synonym: 6-甲基-5-庚烯-2-酮,6-methylhept-5-en-2-one,6-Methyl-5-hepten-2-one

Target: Endogenous Metabolite

DL-Homocysteine thiolactone hydrochloride

Cat.No: T5968

Synonym: DL-Homocysteinethiolactone hydrochloride,DL-高半胱氨酸硫内酯盐酸盐

Target: Endogenous Metabolite

1,3-Dihydroxyacetone

Cat.No: T41122

Target: Endogenous Metabolite

α-Angelica lactone

Cat.No: T7995

Synonym: α-当归内酯,当归内酯,Alpha-Angelica Lactone

Target: Others, GST

Isoalantolactone

Cat.No: T2829

Synonym: (+)-Isoalantolactone,Isohelenin,异土木香内酯

Target: Apoptosis, Endogenous Metabolite, Antibacterial, Autophagy

D-Ribonolactone

Cat.No: T10941

Synonym: D-(+)-核糖酸-1,4-内酯,D-核糖内酯

Target: Endogenous Metabolite, Antibacterial

(-)-Hydroxycitric acid lactone

Cat.No: T12045

Synonym: 藤黄内酯,Garcinia lactone

Target: ATP Citrate Lyase

Butyrolactone I

Cat.No: T25192

Synonym: Olomoucin,丁酸内酯I

Target: CDK

ω-Pentadecalactone

Cat.No: T9327

Synonym: Cyclopentadecanolide,ω-十五内酯,Oxacyclohexadecan-2-one,Exaltolide,Pentadecanolide

Target: Others

2,3-Dehydrokievitone

Cat.No: TN1204

Synonym: 2,3-脱氢维酮

Target: Antifungal

Cat.No: T40815

Target: Others

1-O-Acetyl britannilactone

Cat.No: TN1143

Target: NF-κB, COX

Britannilactone

Cat.No: TQ0118

Synonym: Desacetylinulicin,旋覆花内酯

Target: Others

1,4-D-Gulonolactone

Cat.No: T4719

Synonym: D-Gulonic acid γ-lactone,D-(-)-古洛糖酸-1,4-内酯

Target: Others, Endogenous Metabolite

Cat.No: T5S1897

Target: Apoptosis, Others, JAK

Eurycomalactone

Cat.No: TN1637

Target: Anti-infection, NF-κB

Cat.No: T5728

Synonym: 4-(3,4-Dihydroxyphenyl)-3-buten-2-one

Target: Apoptosis, Reactive Oxygen Species

Cat.No: T2896

Synonym: 土木香内酯,helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,土木香脑,Inula camphor

Target: Apoptosis, STAT, TGF-beta/Smad

trans-Benzylideneacetone

Cat.No: TCS1554

Synonym: 反式苯亚甲基丙酮,Acetocinnamone,亚苄基丙酮

Target: Phospholipase

Hexahydrofarnesyl acetone

Cat.No: T8249

Synonym: 植酮,Phytone

Target: Others, Antibacterial

Dehydrocostus Lactone

Cat.No: T2833

Synonym: Epiligulyl oxide,去氢木香内酯,(-)-Dehydrocostus lactone,去氢木香烃内酯

Target: IκB/IKK

Cat.No: Fr12339

Synonym: 茴香基丙酮

Target: Others

(-)-Corey lactone diol

Cat.No: T8085

Synonym: 科立内脂二醇,Corey Lactone Diol

Target: Others

Ent-toddalolactone

Cat.No: TN7021

Target: Others

Cat.No: T10383

Target: NF-κB

gamma-Nonanolactone

Cat.No: TN6700

Target: Others

DL-Mevalonolactone

Cat.No: T1353

Synonym: 甲瓦龙酸内酯,Mevalonolactone

Target: Others, Endogenous Metabolite

Gamma-decalactone

Cat.No: T8078

Synonym: Decan-4-olide,γ-Decalactone,丙位癸内酯

Target: Others

Cat.No: TCS1709

Synonym: 苄基丙酮,4-Phenylbutan-2-one,Methyl 2-phenylethyl ketone,4-Phenyl-2-butanone

Target: Tyrosinase

Cat.No: T4S0592

Synonym: (+)-Toddalolactone,飞龙掌血内酯,毛两面针素

Target: PAI-1

Undecanoic gamma-lactone

Cat.No: TN6744

Target: Others

Benzylideneacetone

Cat.No: TN6993

Synonym: Benzalacetone

Target: Phospholipase, Endogenous Metabolite

Cat.No: T3384

Synonym: 蟛蜞菊内酯,IKK Inhibitor II

Target: Apoptosis, NF-κB, Lipoxygenase, Caspase

Cat.No: T11680

Target: P450

Farnesylacetone

Cat.No: TN7168

Synonym: (5E,9E)-6,10,14-Trimethylpentadeca-5,9,13-trien-2-one,法尼基丙酮,Farnesyl acetone,E,E-farnesylacetone

Target: Others

Raspberry ketone

Cat.No: T2S0633

Synonym: Oxyphenalon,Rasketone,Aloenin,4-(4-Hydroxyphenyl)-2-butanone,p-Hydroxybenzyl acetone,Frambinone,覆盆子酮

Target: PPAR

D-(+)-Glucono-1,5-lactone

Cat.No: T0933

Synonym: Gluconic acid lactone,Delta-Gluconolactone,Gluconolactone,葡萄糖酸内酯

Target: Others, Reactive Oxygen Species, Endogenous Metabolite

Isodemethylwedelolactone

Cat.No: T5742

Synonym: 异去甲蟛蜞菊内酯,Isodemethylwedelolacton

Target: Others

Cat.No: T8098

Synonym: γ-caprolactone,gamma-己内酯,γ-己内酯

Target: Others

Cat.No: T4S0867

Synonym: DHELWANGIN,广藿香酮

Target: Apoptosis, Antibacterial, Autophagy

Cat.No: T3S0195

Synonym: 诺卡酮,努特卡酮,诺卡酮

Target: AMPK

Raspberry ketone glucoside

Cat.No: T8244

Synonym: 覆盆子酮葡糖苷,树莓苷，覆盆子酮葡萄糖甙

Target: Others

Cat.No: T20345

Synonym: AI3 10572,苯甲酰丙酮,AI3-10572,AI310572

Target: Antibacterial

1beta-Hydroxyalantolactone

Cat.No: TN2539

Target: IL Receptor, TNF

L-Gulono-1,4-lactone

Cat.No: T5578

Target: Others, Endogenous Metabolite

Cat.No: T5654

Target: Others

Dehydrocostuslactone

Cat.No: TN6718

Target: Others

D-Glucuronic acid lactone

Cat.No: T0434

Synonym: Glucuronolactone,D-Glucurone,Dicurone,葡醛内酯

Target: Others, Endogenous Metabolite

Cat.No: T4S0176

Synonym: (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one,桤木酮

Target: Others

Dihydroxyacetone phosphate hemimagnesium salt hydrate

Cat.No: T19281L

Synonym: Dihydroxyacetone phosphate hemimagnesium salt hydrate(57-04-5 free base)

Target: Others

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