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Algestone acetophenide

Algestone acetophenide

产品编号 T25048   CAS 24356-94-3
别名: Neolutin, 苯甲孕酮

Algestone acetophenide (Neolutin) 是用于发情同步的孕酮,已被评估为与庚酸雌二醇联合使用的注射避孕药。它在治疗上也用作局部抗炎药,并在治疗痤疮时局部应用。

TargetMol的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
Algestone acetophenide Chemical Structure
Algestone acetophenide, CAS 24356-94-3
规格 价格/CNY 货期 数量
1 mg ¥ 142 现货
5 mg ¥ 287 现货
10 mg ¥ 428 现货
25 mg ¥ 735 现货
50 mg ¥ 1,090 现货
100 mg ¥ 1,650 现货
200 mg ¥ 2,470 现货
1 mL * 10 mM (in DMSO) ¥ 313 现货
药物设计专题培训
千万补贴 助力科研
BCA蛋白浓度测定试剂盒限时半价
重组蛋白限时优惠
产品目录号及名称: Algestone acetophenide (T25048)
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纯度: 99.65%
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参考文献
产品描述 Algestone acetophenide (Neolutin) is progesterone that used in estrus synchronization and has been evaluated as an injectable contraceptive in combination with estradiol enanthate. It is also used therapeutically as a topical anti-inflammatory and is applied topically in the therapy of ACNE.
体外活性 Every 21 days or so, each female received a single dose of combined hormonal contraceptive (algestone acetophenide and 17-enanthate estradiol) in a total of five doses throughout the experiment.?The physiological parameters were accessed by means of 13 blood samples from each female, whereas three were gathered during the baseline and 10 samples were collected during the treatment phase.?The results showed that the contraceptive use provoked changes in hematological coagulation factors such as an increase in the amount of platelets (p = 0.039) and a reduction in both prothrombin (p
别名 Neolutin, 苯甲孕酮
分子量 448.59
分子式 C29H36O4
CAS No. 24356-94-3

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度

DMSO: 10.83 mg/ml (24.15 mM)

溶液配制表

可选溶剂 浓度 体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2292 mL 11.146 mL 22.2921 mL 55.7302 mL
5 mM 0.4458 mL 2.2292 mL 4.4584 mL 11.146 mL
10 mM 0.2229 mL 1.1146 mL 2.2292 mL 5.573 mL
20 mM 0.1115 mL 0.5573 mL 1.1146 mL 2.7865 mL

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TargetMol Library Books参考文献

1. Rodrigues R C , Belham F S , Garcia A , et al. Continuous Use of Combined Hormonal Contraceptive and the Effect on Blood Coagulation Factors in Female Capuchin Monkeys ( Sapajus libidinosus )[J]. International Journal of Endocrinology, 2019, 2019:1-9. 2. Coutinho EM, Spinola P, Tomaz G, Morais K, Nassar de Souza R, Sabino Pinho Neto J, de Barros Leal W, Bomfim Hippolito S, D'Aurea Abranches A. Efficacy, acceptability, and clinical effects of a low-dose injectable contraceptive combination of dihydroxyprogesterone acetophenide and estradiol enanthate. Contraception. 2000 Apr;61(4):277-80. PubMed PMID: 10899484. 3. Martínez GH, Castañeda A, Correa JE. Vaginal bleeding patterns in users of Perlutal, a once-a-month injectable contraceptive consisting of 10 mg estradiol enanthate combined with 150 mg dihydroxyprogesterone acetophenide. A trial of 5462 woman-months. Contraception. 1998 Jul;58(1):21-7. PubMed PMID: 9743892. 4. Coutinho EM, Spinola P, Barbosa I, Gatto M, Tomaz G, Morais K, Yazlle ME, de Souza RN, Pinho Neto JS, Leal Wde B, Leal C, Hippolito SB, Abranches AD. Multicenter, double-blind, comparative clinical study on the efficacy and acceptability of a monthly injectable contraceptive combination of 150 mg dihydroxyprogesterone acetophenide and 10 mg estradiol enanthate compared to a monthly injectable contraceptive combination of 90 mg dihydroxyprogesterone acetophenide and 6 mg estradiol enanthate. Contraception. 1997 Mar;55(3):175-81. PubMed PMID: 9115007.

相关化合物库

该产品包含在如下化合物库中:
经典已知活性库 NO PAINS 化合物库 已知活性化合物库

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母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。

体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。

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Keywords

Algestone acetophenide 24356-94-3 Others Neolutin 苯甲孕酮 Inhibitor inhibitor inhibit

 

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