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10

抑制剂 & 化合物

63

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T41345	AFMK Formyl-N-acetyl-5-methoxykynurenamine,Acetyl-N-formyl-5-methoxykynurenamine	Apoptosis; Free radical scavengers; Antioxidant; Endogenous Metabolite	Apoptosis; Metabolism; oxidation-reduction
	AFMK (Formyl-N-acetyl-5-methoxykynurenamine) 是褪黑激素的活性代谢物，具有抗氧化和自由基清除活性。 AFMK 是一种凋亡调节剂，可提高吉西他滨在 PANC-1 细胞中的抗肿瘤作用。
T36619	Aligeron	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Aligeron 是一种非选择性的prostaglandin (PG)拮抗剂，对PGF2α和PGE2诱导的猫血压下降有抑制作用，可用于抑制PGF2α诱导的小鼠腹泻和PGE2诱导的大鼠爪水肿。Aligeron 对血管并发症具有抗氧化保护作用。
T63189	EGFR/BRAF-IN-1
	EGFR/BRAF-IN-1 是 2,3-dihydropyrazino[1,2-a]indole-1,4-dione 衍生物，是 EGFR/BRAF 的有效抑制剂，能够抑制 BRAFV600E(IC50:45 nM)，对癌细胞增殖 (GI50=35 nM)具有抑制作用，具有良好的抗氧化作用。
T72506	Antioxidant agent-8
	Antioxidant agent-8是一种口服活性的Aβ1-42沉积抑制剂。其抑制原纤维聚集的IC50值为11.15 µM，促进原纤维分解的IC50值为6.87 µM。此外，Antioxidant agent-8对Cu2+诱导的Aβ1-42原纤维聚集有抑制作用（IC50=3.69 µM），并能促进Cu2+诱导的Aβ1-42原纤维分解（IC50=3.35 µM）。该化合物具备抗氧化活性、抗炎活性、生物安全性、血脑屏障通透性和神经保护作用。
T71552	ASC-JM-17
	ASC-JM-17 is an activator of both Nrf1 and Nrf2 proteins. ASC-JM17 acts on Nrf1, Nrf2 and Hsf1 to increase the expression of proteasome subunits, antioxidant enzymes and molecular chaperones. ASC-JM17 ameliorates toxicity of the mutant androgen receptor (AR) responsible for SBMA in cell, fly and mouse models. Knockdown of the Drosophila Nrf1 and Nrf2 ortholog cap ‘n’ collar isoform-C, but not Hsf1, blocks the protective effect of ASC-JM17 on mutant AR-induced eye degeneration in flies.
T35962	MitoPBN
	MitoPBN is a mitochondria-targeted antioxidant. It accumulates in the mitochondria following the generation of a mitochondrial membrane potential by succinate, an effect that is blocked by addition of the mitochondrial membrane potential uncoupler FCCP . MitoPBN inhibits superoxide activation of mitochondrial uncoupling protein 1 (UCP1), UCP2, and UCP3 when used at a concentration of 250 nM in vitro but does not react with superoxide. It traps hydroxyl (IC50 = ~77 μM) and carbon-centered radical...
T35860	AP39
	AP39 is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria. It consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an aliphatic linker. AP39 (30-300 nM) dose-dependently increases H2S levels in endothelial cells, predominantly in mitochondrial regions. It stimulates mitochondrial electron transport and improves cellular bioenergetic function at lower concentrations (30-100 nM), while having an i...
T78698	Aβ-IN-6
	Aβ-IN-6降低小胶质细胞释放的促炎细胞因子，能有效促进Nrf2核转位并抑制Aβ寡聚体的形成。通过调节体内氧化应激的氧化还原敏感信号通路，Aβ-IN-6展现出一致的神经保护效应。具有口服活性的Aβ-IN-6表现出抗炎、抗氧化和抗寡聚特性，并显示出作为阿尔茨海默病(AD)治疗研究潜力。
T80286	TP4 (Nile tilapia piscidin)	Necroptosis	Apoptosis
	TP4（Nile tilapia piscidin）是一种piscidin样的抗菌肽，其口服活性被证实。此化合物对多种革兰氏阳性及阴性菌株均有效（MIC: 0.03-10 μg/mL），并展现了溶血性。TP4还能增强免疫响应、提升抗氧化能力和改善肠道健康，助于防御细菌感染。除此之外，TP4显示抗肿瘤效果，并可通过激发癌细胞线粒体功能障碍导致坏死（necrosis）。
T72454	AChE/BChE/MAO-B-IN-4
	AChE/BChE/MAO-B-IN-4 是一种 1-茚满酮衍生物，是一种有效的MAO-B 抑制剂，对人MAO-B 的IC50为 0.0359 μM。AChE/BChE/MAO-B-IN-4 是一种有效的AChE 和BChE 酶抑制剂，对人AChE 和BChE 酶的IC50值分别为 0.0473 μM 和 0.0782 μM。AChE/BChE/MAO-B-IN-4 显示出显着的抗氧化活性，并防止β-淀粉样蛋白斑块聚集。AChE/BChE/MAO-B-IN-4 具有用于阿尔茨海默病 (AD) 研究的潜力。

化合物

Cat.No: T41345

Synonym: Formyl-N-acetyl-5-methoxykynurenamine,Acetyl-N-formyl-5-methoxykynurenamine

Target: Apoptosis, Free radical scavengers, Antioxidant, Endogenous Metabolite

Cat.No: T36619

Target: Prostaglandin Receptor

Cat.No: T63189

Antioxidant agent-8

Cat.No: T72506

Cat.No: T71552

Cat.No: T35962

Cat.No: T35860

Cat.No: T78698

TP4 (Nile tilapia piscidin)

Cat.No: T80286

Target: Necroptosis

AChE/BChE/MAO-B-IN-4

Cat.No: T72454

Cat. No.	Product Name	Target	Signaling Pathways
T7934	7-Methylcoumarin	Others	Others
	7-Methylcoumarin 具有很强的保肝活性。
TQ0211	Brusatol (+)-Brusatol,鸦胆子苦醇,NSC 172924	Others; Ferroptosis; Nrf2	Apoptosis; Immunology/Inflammation; Others
	Brusatol (NSC-172924) 是一种从鸦胆子植物中分离出来的天然产物，抑制Nrf2通路，可使多种癌细胞对 Cisplatin 和其他化疗药物敏感。它可开发为辅助化疗化合物，可增加细胞凋亡。
T5725	Salvianolic acid B 丹酚酸B,lithospermic acid B,Dan Shen Suan B	Sirtuin; Autophagy	Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Salvianolic acid B (Dan Shen Suan B) 是一种来自丹参提取物的水溶性抗氧化剂，具有抗血小板聚集、抗凝和抗血栓作用。它常用来研究微循环疾病。
T2727	Salvianolic acid B	Others	Others
	Salvianolic acid B (Dan Shen Suan B) 是一种来自丹参提取物的水溶性抗氧化剂，具有抗血小板聚集、抗凝和抗血栓作用。它常用来研究微循环疾病。
T1368	Methyl 3,4-dihydroxybenzoate 3,4-Dihydroxybenzoic acid methyl ester,Methyl protocatechuate,原儿茶酸甲酯,3,4-二羟基苯甲酸甲酯,Protocatechuic acid methyl ester	Apoptosis; Antioxidant; Nrf2	Apoptosis; Immunology/Inflammation; oxidation-reduction
	Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester) 是绿茶中发现的主要代谢产物，是一种多酚，有抗氧化和抗炎作用。
T6S0078	Oxypeucedanin hydrate Prangolarin Hydrate,水合氧化前胡素	Antioxidant	oxidation-reduction
	Oxypeucedanin hydrate (Prangolarin Hydrate) 是一种分离自D. anethifolia 中的天然香豆素化合物，存在于几种植物中，具有抗感染和抗真菌活性。
T2925	Schisandrin B gamma-Schisandrin,Schizandrin B,五味子素B,五味子乙素,Schisandrin B (Sch B),Wuweizisu-B	ATM/ATR; Reactive Oxygen Species; Autophagy	Autophagy; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
	Schisandrin B (Schisandrin B (Sch B)) 是从五味子中分离联苯环辛二烯衍生物，对啮齿类动物的肝脏和心脏的抗氧化作用。
TN1490	Chrysoeriol	ERK; p38 MAPK; Akt	Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
	Chrysoeriol 是一种天然黄酮，可从热带植物Coronopus didymus 中提取获得，具有强大的抗氧化功能，能够抑制脂质的过氧化。
T2P2898	Neodiosmin 新地奥斯明,Diosmetin-7-neohesperidoside,新地奥司明,Diosmetin-7-O-neohesperidoside	Antioxidant	oxidation-reduction
	Neodiosmin (Diosmetin-7-O-neohesperidoside) 是一种黄酮苷，分离自柑桔叶中。
T3905	Isomangiferin 芒果	Free radical scavengers; Antiviral; Influenza Virus	Immunology/Inflammation; Microbiology/Virology; oxidation-reduction
	Isomangiferin 是一种天然产物，具有抗病毒的作用。它还具有抗氧化和自由基清除活性。
T3S1692	Octahydrocurcumin	Anti-infection; NF-κB; Reactive Oxygen Species; ROS	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Octahydrocurcumin 是一种姜黄素的氢化衍生物，是姜黄素的代谢物。
T3S1196	mogroside IV	Others	Others
	Mogroside IV 是一种从罗汉果提取物中分离得到的三萜糖苷。它是非糖类甜味剂，甜度比蔗糖高。它具有抗氧化，抗糖尿病和抗癌作用。
T3S1775	Tectochrysin NSC 80687,Techtochrysine,Techtochrysin,柚木柯因	NF-κB; STAT	JAK/STAT signaling; NF-κB; Stem Cells
	Tectochrysin (Techtochrysine) 是Alpinia oxyphylla 的主要黄酮类化合物之一，能够抑制NF-κB 活性。
T2838	Naringenin 柚皮素,Naringetol,S-Dihydrogenistein,Pelargidanon,Salipurol,NSC 11855,NSC 34875	P450; Influenza Virus; Reactive Oxygen Species; Endogenous Metabolite; PPAR	DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Naringenin (NSC-11855) 是葡萄柚中主要的黄烷酮，可作为抗氧化剂、自由基清除剂、抗炎剂、碳水化合物代谢促进剂、免疫系统调节剂。
T7028	Licochalcone C LICOCHALCONEC,甘草查尔酮C	Phosphatase; Antioxidant; Glucosidase	Metabolism; oxidation-reduction
	Licochalcone C (LICOCHALCONEC) 能够抑制 α-葡萄糖苷酶，其对 α-葡萄糖苷酶的 IC50 <100 nM，对蛋白酪氨酸磷酸酶 1B 的 IC50=92.43 μM 。
T3736	Olivetol 橄榄醇,5-Pentylresorcinol,5-n-Amylresorcinol,3,5-二羟基戊苯	Cannabinoid Receptor; P450; IκB/IKK	GPCR/G Protein; Metabolism; NF-κB
	Olivetol (5-n-Amylresorcinol) 是天然多酚类化合物，存在于地衣中，或由一些昆虫产生。它竞争性地抑制大麻素受体CB1和CB2，抑制 CYP2C19 (IC50=15.3 μM;Ki=7.21 μM) 和 CYP2D6 (IC50=2.71 μM;Ki=2.87 μM) 的活性。
T6S1369	Vitexin 牡荆素,Apigenin-8-C-glucoside	Antioxidant	oxidation-reduction
	Vitexin 是一种存在于多种药用植物（如榕树、螺旋藻）中的 c-糖基化的黄酮。它具有广泛的药理作用，包括抗氧化，抗癌，抗炎，抗痛觉过敏和神经保护作用。
T2S1008	Oxysophoridine Sophoridine N-oxide,氧化槐定碱	Apoptosis; Antioxidant	Apoptosis; oxidation-reduction
	Oxysophoridine (Sophoridine N-oxide) 是从苦豆子中提取的一种生物碱，具有抗发炎，抗氧化应激和抗凋亡的作用。
T6S1683	Demethoxycurcumin Curcumin II,去甲氧基姜黄素,Desmethoxycurcumin,脱甲氧姜黄,Monodemethoxycurcumin	Apoptosis; Antioxidant; Antibacterial; Autophagy	Apoptosis; Autophagy; Microbiology/Virology; oxidation-reduction
	Demethoxycurcumin (Desmethoxycurcumin) 是姜黄素的主要活性成分，有抗炎和抗癌作用。
TN1420	Bacopaside I	Others	Others
	Bacopaside I 是一种皂苷，分离自 Bacopa monniera 中，具有抗氧化活性和清除自由基的功能，有抗抑郁作用。
T5S1103	Isoliensinine 异莲心碱,Isoliensinin	Apoptosis; Antioxidant	Apoptosis; oxidation-reduction
	Isoliensinine (Isoliensinin) 是从水芙蓉种子胚中提取的一种双苄基异喹啉生物碱，能诱导三阴性乳腺癌细胞凋亡，具有抗氧化、抗炎、抗癌活性。
T2978	Mogroside V	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	Mogroside V 是三萜糖苷，是非糖类甜味剂，甜度比蔗糖甜高300倍。它具有抗氧化，抗糖尿病和抗癌作用。
T6S1684	8-Gingerol	Antioxidant; Antibacterial; TRP/TRPV Channel	Membrane transporter/Ion channel; Microbiology/Virology; oxidation-reduction
	8-Gingerol 分离自姜的根状茎，是口服有效的 TRPV1激活剂，EC50值为5.0 µM。8-Gingerol 抑制 COX-2，还能抑制体外 H. pylori 的生长。
TN1861	Licoflavone C 4',5,7-Trihydroxy-8-prenylflavone	Antioxidant; Antifungal	Microbiology/Virology; oxidation-reduction
	Licoflavone C (4',5,7-Trihydroxy-8-prenylflavone) 是从 Glycyrrhiza inflata 的根部分离出来的异戊二烯基黄酮化合物，具有抗氧化和抗真菌活性，在培养的人类外周淋巴细胞中，它对 DAU 或 MMC 诱导的染色体损伤具有保护作用。Licoflavone C 可用于研究真菌感染。
TCS2070	Homogentisic acid 高龙胆酸,2,5-dihydroxyphenylacetic acid,Homogentisinic Acid,Melanic acid	Antioxidant; Endogenous Metabolite	Metabolism; oxidation-reduction
	Homogentisic acid (2,5-dihydroxyphenylacetic acid) 是一种尿液和血清代谢物中的特定代谢物，可用于尿黑酸尿症的诊断。
T4S0867	Pogostone DHELWANGIN,广藿香酮	Apoptosis; Antibacterial; Autophagy	Apoptosis; Autophagy; Microbiology/Virology
	Pogostone (DHELWANGIN) 是从薄荷中分离出，对革兰氏阴性菌、革兰氏阳性菌、大肠埃希菌等具有强效抗菌、抗真菌活性。它诱导细胞凋亡和自噬。
T3893	Forsythoside B 连翘酯苷 B,连翘脂苷B	TNF; NF-κB	Apoptosis; NF-κB
	Forsythoside B 是传统中药植物独一味叶子中分离的一种苯乙醇苷。它可抑制 TNF-alpha，IL-6，IκB，调节 NF-κB。它抑制炎症反应，具有抗氧化和神经保护作用。
T41242	Uric acid sodium	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Uric acid sodium 是氧自由基 (oxygen radical) 的清除剂，是一种有效的、常见的抗氧化剂，有助于维持机体血压稳定和抗氧化应激。Uric acid sodium 能清除活性氧 (ROS)，如单线态氧和过氧亚硝酸盐，对脂质过氧化有抑制作用，与痛风性关节病的发病机理和草酸钙结石的形成有关。
T5S1805	5,7-Dihydroxychromone 5,7-Dihydroxy-4H-Chromen-4-One,5,7-二羟基色酮,5,7-二羟基色原酮	Others; Virus Protease; PARP; Caspase; Nrf2	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Microbiology/Virology; Others; Proteases/Proteasome
	5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) 是一种Cudrania tricuspidata 的提取物，通过激活 Nrf2/ARE 信号对 6-OHDA 诱导的氧化应激和细胞凋亡发挥神经保护作用。它抑制 6-OHDA 诱导的 SH-SY5Y 细胞中活化的caspase-3，caspase-9以及切割的PARP 表达。
TN1962	Myricetin 3-O-galactoside Myricetin 3-O-beta-D-galactopyranoside	NOS; Xanthine Oxidase	Immunology/Inflammation; Metabolism
	Myricetin 3-O-galactoside (Myricetin 3-O-beta-D-galactopyranoside) 可抑制黄嘌呤氧化酶 (xanthine oxidase; XO) 活性，脂质过氧化并清除自由基。杨梅素3- o -半乳糖苷具有很多作用包括细胞毒性、抗氧化、抗基因毒性、抗感染性、抗炎作用和抗氧化活性，其主要作用是抑制诱导型一氧化氮合酶(iNOS)的合成。Myricetin 3-O-galactoside 抑制脂质过氧化的 IC50 为 160 μg/mL。
T3753	Sinapinic Acid Sinapic acid,芥子酸,Synapoic acid	Apoptosis; RAAS; Reactive Oxygen Species; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB
	Sinapinic Acid (Synapoic acid) 是从 Hydnophytum formicarumJack. 根中分离到的酚类，是HDAC 抑制剂，对ACE-I 的活性也有抑制作用。它有抗肿瘤活性，诱导肿瘤细胞凋亡，具有抗氧化、抗糖尿病的作用。
T3123	Allicin	ERK; IL Receptor; Others; IκB/IKK; p38 MAPK; TNF; ROS; Caspase; Antifection	Apoptosis; Immunology/Inflammation; MAPK; Microbiology/Virology; NF-κB; Others; Proteases/Proteasome
	Allicin 具有抗氧化、杀菌、抗癌、抗炎活性，对肠上皮细胞具有抑制性免疫调节作用。 Allicin 能显着抑制胰岛素诱导的血管平滑肌细胞的增殖和迁移，这可能与抑制 ERK 信号通路的激活有关。 Allicin 有利于降低高胆固醇血症大鼠的血液胆固醇、甘油三酯水平和收缩压，它可能有益于影响动脉粥样硬化的两个危险因素——高脂血症和高血压。
T6S2099	Geraniin	Antioxidant; TNF	Apoptosis; oxidation-reduction
	Geraniin 是一种肿瘤坏死因子α释放抑制剂，其IC50值为 43 μM，具有抗肿瘤、抗炎和抗高血糖活性。
T5S1172	Tiliroside 银椴甙,Tribuloside,银椴苷；椴树苷	Antioxidant	oxidation-reduction
	Tiliroside (Tribuloside) 是糖苷类黄酮，是 α-淀粉酶的非竞争性抑制剂(Ki:84.2 μM)。它抑制胃肠道中碳水化合物的消化和葡萄糖的吸收，具有抗糖尿病作用。
T2S1865	Octyl gallate Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8,没食子酸辛酯	Antioxidant; Influenza Virus; Reactive Oxygen Species; Antibacterial; Antifungal; HSV	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; oxidation-reduction
	Octyl gallate (Octyl 3,4,5-trihydroxybenzoate) 具有抗菌、抗氧化作用，有选择性和敏感性的荧光特性，广泛用作食品添加剂。它对 HSV-1，水泡性口炎病毒和脊髓灰质炎病毒有显著的抗病毒作用。
T24050	Eugenone Eugenon,J167.369F
	Eugenone has a prooxidant and antioxidant effect.
TN6617	Malvidin-3-O-arabinoside chloride
	Malvidin-3-O-arabinoside chloride has antioxidant activity.It has potential preventive effect in colorectal diseases.
TN3574	Canadine	P450	Metabolism
	Canadine has antioxidant activity with low-toxic effect.
TN1871	Ligustroside	EGFR; Lipoxygenase; COX	Angiogenesis; Immunology/Inflammation; JAK/STAT signaling; Metabolism; Neuroscience; Tyrosine Kinase/Adaptors
	Ligustroside shows little antioxidant, and anti-inflammatory properties, it shows a significant inhibition effect on prostaglandin E2 (PGE2)-release. Ligustroside shows moderate antiviral activities against parainfluenza type 3 virus.
TN2116	Pteropodine	BCL; Calcium Channel; 5-HT Receptor	Apoptosis; GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Pteropodine acts as a positive modulator of muscarinic M(1) and 5-HT(2) receptors. Pteropodine shows antigenotoxic, antioxidant and lymphocyte induction effects, it also shows strong apoptotic effect on acute leukaemic lymphoblasts.
T10524	β-Cryptoxanthin (3R)-β-Cryptoxanthin	Others	Others
	β-Cryptoxanthin is isolated from Satsuma mandarin orange with an anti-stress effect. It is an oxygenated carotenoid and an antioxidant.
TN2084	Piperitol	Others	Others
	Piperitol has in vitro antioxidant potential, it also exhibits a stronger CNS depressant effect than that of M. rotundifolia.
TN4527	Methyl 3-(2,4-dihydroxyphenyl)propionate	Others	Others
	Methyl 3-(2,4-dihydroxyphenyl)propionate has inhibitory effects on tyrosinase, antioxidant ability, and lightening effect of ultraviolet B (UVB)-induced hyperpigmentation.
TN1542	Cycloheterophyllin	NADPH-oxidase; PKA; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Tyrosine Kinase/Adaptors
	Cycloheterophyllin has an antioxidant effect, it is a photoprotective agent that inhibits ultraviolet A (UVA)-induced oxidative stress and damage, and could be used in the research on and prevention of skin photoaging.
T6596	Morin monohydrate Aurantica,桑色素.桑黄素,Morin Hydrate	Others	Others
	Morin monohydrate（Aurantica）是一种植物源黄酮类天然产物，抗氧化作用较弱。Morin作为一种荧光螯合剂，可应用于铝物种的生成过程
TN1632	Euparin	Antifection	Microbiology/Virology
	Euparin exhibits a moderate antioxidant activity, it also exhibits antifungal activity against Trichophyton mentagrophytes. Euparin has antiviral activity, it exerts its effect during the early events of the replication cycle, from the virus adsorption to
TN3692	Conduritol A	TNF	Apoptosis
	Conduritol A has a hypoglycemic effect, can have an effect on regulating the metabolism of blood lipid, free-radical scavenging, enhancing the antioxidant ability, potentiating immune function; it also can markedly prevent the diabetic rats from getting c
TN3914	Echinatine	ATPase; IL Receptor; TNF	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel
	Echinatin exerts a protective effect against ischemia/reperfusion (I/R)-induced myocardial injury on hearts, this effect may be attributed to the antioxidant and anti-inflammatory activities of this compound. Echinatin can inhibit DNP-ATPase activity whil
T72806	Isobellidifolin 异雏菊叶龙胆酮
	Isobellidifolin，一种蒽酮类化合物，同时兼具自由基清除剂和抗氧化功能，亦显示出有效的抗真菌活性。
TN4273	Isocoronarin D	Others	Others
	Isocoronarin D is a main active ingredient for inducing death of the tested cancer cells, it possesses a wide anti-cancer capability. Isocoronarin D may have potential chemopreventive activity, it can activate antioxidant response element (ARE) (EC50 57.6 ± 2.4 uM). It also shows the highest Hb F induction effect of 1.6-fold at 20 microM.
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天然产物

7-Methylcoumarin

Cat.No: T7934

Target: Others

Cat.No: TQ0211

Synonym: (+)-Brusatol,鸦胆子苦醇,NSC 172924

Target: Others, Ferroptosis, Nrf2

Salvianolic acid B

Cat.No: T5725

Synonym: 丹酚酸B,lithospermic acid B,Dan Shen Suan B

Target: Sirtuin, Autophagy

Salvianolic acid B

Cat.No: T2727

Target: Others

Methyl 3,4-dihydroxybenzoate

Cat.No: T1368

Synonym: 3,4-Dihydroxybenzoic acid methyl ester,Methyl protocatechuate,原儿茶酸甲酯,3,4-二羟基苯甲酸甲酯,Protocatechuic acid methyl ester

Target: Apoptosis, Antioxidant, Nrf2

Oxypeucedanin hydrate

Cat.No: T6S0078

Synonym: Prangolarin Hydrate,水合氧化前胡素

Target: Antioxidant

Cat.No: T2925

Synonym: gamma-Schisandrin,Schizandrin B,五味子素B,五味子乙素,Schisandrin B (Sch B),Wuweizisu-B

Target: ATM/ATR, Reactive Oxygen Species, Autophagy

Cat.No: TN1490

Target: ERK, p38 MAPK, Akt

Cat.No: T2P2898

Synonym: 新地奥斯明,Diosmetin-7-neohesperidoside,新地奥司明,Diosmetin-7-O-neohesperidoside

Target: Antioxidant

Cat.No: T3905

Synonym: 芒果

Target: Free radical scavengers, Antiviral, Influenza Virus

Octahydrocurcumin

Cat.No: T3S1692

Target: Anti-infection, NF-κB, Reactive Oxygen Species, ROS

Cat.No: T3S1196

Target: Others

Cat.No: T3S1775

Synonym: NSC 80687,Techtochrysine,Techtochrysin,柚木柯因

Target: NF-κB, STAT

Cat.No: T2838

Synonym: 柚皮素,Naringetol,S-Dihydrogenistein,Pelargidanon,Salipurol,NSC 11855,NSC 34875

Target: P450, Influenza Virus, Reactive Oxygen Species, Endogenous Metabolite, PPAR

Cat.No: T7028

Synonym: LICOCHALCONEC,甘草查尔酮C

Target: Phosphatase, Antioxidant, Glucosidase

Cat.No: T3736

Synonym: 橄榄醇,5-Pentylresorcinol,5-n-Amylresorcinol,3,5-二羟基戊苯

Target: Cannabinoid Receptor, P450, IκB/IKK

Cat.No: T6S1369

Synonym: 牡荆素,Apigenin-8-C-glucoside

Target: Antioxidant

Cat.No: T2S1008

Synonym: Sophoridine N-oxide,氧化槐定碱

Target: Apoptosis, Antioxidant

Demethoxycurcumin

Cat.No: T6S1683

Synonym: Curcumin II,去甲氧基姜黄素,Desmethoxycurcumin,脱甲氧姜黄,Monodemethoxycurcumin

Target: Apoptosis, Antioxidant, Antibacterial, Autophagy

Cat.No: TN1420

Target: Others

Cat.No: T5S1103

Synonym: 异莲心碱,Isoliensinin

Target: Apoptosis, Antioxidant

Cat.No: T2978

Target: AMPK

Cat.No: T6S1684

Target: Antioxidant, Antibacterial, TRP/TRPV Channel

Cat.No: TN1861

Synonym: 4',5,7-Trihydroxy-8-prenylflavone

Target: Antioxidant, Antifungal

Homogentisic acid

Cat.No: TCS2070

Synonym: 高龙胆酸,2,5-dihydroxyphenylacetic acid,Homogentisinic Acid,Melanic acid

Target: Antioxidant, Endogenous Metabolite

Cat.No: T4S0867

Synonym: DHELWANGIN,广藿香酮

Target: Apoptosis, Antibacterial, Autophagy

Cat.No: T3893

Synonym: 连翘酯苷 B,连翘脂苷B

Target: TNF, NF-κB

Uric acid sodium

Cat.No: T41242

Target: Reactive Oxygen Species

5,7-Dihydroxychromone

Cat.No: T5S1805

Synonym: 5,7-Dihydroxy-4H-Chromen-4-One,5,7-二羟基色酮,5,7-二羟基色原酮

Target: Others, Virus Protease, PARP, Caspase, Nrf2

Myricetin 3-O-galactoside

Cat.No: TN1962

Synonym: Myricetin 3-O-beta-D-galactopyranoside

Target: NOS, Xanthine Oxidase

Cat.No: T3753

Synonym: Sinapic acid,芥子酸,Synapoic acid

Target: Apoptosis, RAAS, Reactive Oxygen Species, HDAC

Cat.No: T3123

Target: ERK, IL Receptor, Others, IκB/IKK, p38 MAPK, TNF, ROS, Caspase, Antifection

Cat.No: T6S2099

Target: Antioxidant, TNF

Cat.No: T5S1172

Synonym: 银椴甙,Tribuloside,银椴苷；椴树苷

Target: Antioxidant

Cat.No: T2S1865

Synonym: Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8,没食子酸辛酯

Target: Antioxidant, Influenza Virus, Reactive Oxygen Species, Antibacterial, Antifungal, HSV

Cat.No: T24050

Synonym: Eugenon,J167.369F

Malvidin-3-O-arabinoside chloride

Cat.No: TN6617

Cat.No: TN3574

Target: P450

Cat.No: TN1871

Target: EGFR, Lipoxygenase, COX

Cat.No: TN2116

Target: BCL, Calcium Channel, 5-HT Receptor

β-Cryptoxanthin

Cat.No: T10524

Synonym: (3R)-β-Cryptoxanthin

Target: Others

Cat.No: TN2084

Target: Others

Methyl 3-(2,4-dihydroxyphenyl)propionate

Cat.No: TN4527

Target: Others

Cycloheterophyllin

Cat.No: TN1542

Target: NADPH-oxidase, PKA, PKC

Morin monohydrate

Cat.No: T6596

Synonym: Aurantica,桑色素.桑黄素,Morin Hydrate

Target: Others

Cat.No: TN1632

Target: Antifection

Cat.No: TN3692

Target: TNF

Cat.No: TN3914

Target: ATPase, IL Receptor, TNF

Isobellidifolin

Cat.No: T72806

Synonym: 异雏菊叶龙胆酮

Cat.No: TN4273

Target: Others

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