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Targets Recommended: Apoptosis Reactive Oxygen Species

158

抑制剂 & 化合物

12

天然产物

2

化合物库

1

TargetMol 试剂盒

23

重组蛋白

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Cat. No.	Product Name
L3980	DNA损伤/修复库Plus		667 compounds
	667 种 DNA 损伤/修复靶向、结构新颖的化合物；
L3900	DNA 损伤和修复分子库		910 compounds
	910 个与 DNA 损伤和修复紧密相关的化合物集合，是高通量筛选，高内涵筛选的良好载体；

化合物库

DNA损伤/修复库Plus

Cat.No: L3980

Compounds: 667

DNA 损伤和修复分子库

Cat.No: L3900

Compounds: 910

Cat. No.	Product Name	Form	Specificity Of Inhibition
C0113	Magrose Beads Heparin 肝素磁珠

TargetMol 试剂盒

Cat.No: C0113

Cat. No.	Product Name	Target	Signaling Pathways
T20543	Flurochloridone 氟咯草酮,R 40244,R-40244,R40244,EPA Pesticide Chemical Code 128401	Apoptosis; Reactive Oxygen Species	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
	Flurochloridone (R 40244) 是一种选择性除草剂。 Flurochloridone 诱导细胞凋亡并受线粒体功能障碍和氧化应激的调节。
T20573	Carbetamide Legurame,卡草胺,EPA Pesticide Chemical Code 259200,Carbetamid,11,561 RP,Carbetamex,Caswell No. 159B	Others	Others
	Carbetamide (Caswell No. 159B) 是一种除草剂，在土壤中具有良好的流动性。
T20669	Bentazone 苯达松,BAS 351-07H,EPA Pesticide Chemical Code 275200
	Paicaotan is a heterocyclic herbicide. It can removal broadleaf weeds and sedge in the soybean field.
T29000	Tralomethrin EPA Pesticide Chemical Code 121501,SAGA,HAG-107,HAG 107,Scout
	Tralomethrin is used as a pyrethroid insecticide. It modifies the gating kinetics of the sodium channels in neurons, increases the length of time the channel remains open after a stimulus, thereby depolarizing the neuron for a longer period of time. This leads to uncontrolled spasms, paralysis, and eventual death.
T23768	Azothoate Caswell No. 206A,L 1058,L-1058,EPA Pesticide Chemical Code 206100,L1058
	Azothoate is an insecticide agent.
T24172	Iodofenphos NSC-190998,EPA Pesticide Chemical Code 309700,Nuvanol N,NSC190998,NSC 190998
	Iodofenphos is an obsolete insecticide.
T29981	Amidochlor Caswell No. 005B,EPA Pesticide Chemical Code 128001,MON 4620,MON 4621,Limit
	Amidochlor is a growth regulator.
T71402	Nicorandil-d4
	Nicorandil-d4 is intended for use as an internal standard for the quantification of nicorandil by GC- or LC-MS. Nicorandil is an activator of sulfonylurea receptor 2B (SUR2B) linked to ATP-sensitive potassium channel Kir6.2 (EC50 = ~10 µM) and a nitric oxide (NO) donor. It is selective for SUR2B/Kir6.2 over the SUR2A/Kir6.2 channel (EC50 = >500 µM). Nicorandil activates soluble guanylate cyclase in a cell-free assay and relaxes partially depolarized isolated bovine coronary artery strips (EC50 =...
T70804	Itasetron hydrochloride monohydrate
	Itasetron hydrochloride monohydrate is a potent 5HT-3 receptor antagonist.
T69692	BRD-K25923209
	BRD-K25923209 is a novel inhibitor of BAF transcriptional repression.
T12705	Reparixin L-lysine salt REPERTAXIN L-赖氨酸盐,Repertaxin L-lysine salt	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	Reparixin L-lysine salt (Repertaxin L-lysine salt) 是趋化因子受体1/2 活化的变构抑制剂。
T3174	Taprenepag CP-544326	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Taprenepag (CP-544326) 是一种有效的选择性前列腺素 E2 受体激动剂，EC50为 2.8 nM，可用于研究开角治疗高眼压和青光眼的试验。
T16126	Monepantel AAD1566,PPL-1	AChR	Neuroscience
	Monepantel (AAD1566) 是一种有机驱虫剂，也是来自蛔虫和食管造口的烟碱乙酰胆碱受体拮抗剂，广泛用于农牧业除虫。
T1250	Thio-TEPA Tiofosyl,Triethylenethiophosphoramide,三亚乙基硫代磷酰胺,Tiofosfamid	DNA Alkylator/Crosslinker; DNA Alkylation; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Thio-TEPA (Tiofosyl) 是一种具有抗肿瘤作用的 DNA 烷化剂。
T12406	PEPA	iGluR	Membrane transporter/Ion channel; Neuroscience
	PEPA 是一种变构 AMPA 受体调节剂，可与 GluA2o 和 GluA3o LBD 结合，可用作 AMPA 受体异质性的指标。
T15259	Evatanepag CP-533536 free acid,2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Evatanepag (CP-533536 free acid) 是一种 EP2 受体选择性前列腺素 E2 (PGE2) 激动剂，可诱导局部骨形成，EC50 为 0.3 nM。它在大鼠骨折愈合模型中以单剂量局部给药时表现出愈合骨折的能力。
T24449	Mepacrine Haffkinine,Erion	Others	Others
	Mepacrine (Erion) 是一种吖啶衍生物，以前广泛用作抗疟药。它在细胞生物学实验中用作磷脂酶A2的抑制剂。
TP1111L1	Tirzepatide sodium salt LY-3298176 sodium salt,Tirzepatide sodium salt（2023788-19-2 free base）	Glucagon Receptor	GPCR/G Protein
	Tirzepatide sodium salt (LY3298176 sodium salt) 是新型 GIP 和 GLP-1 受体双重激动剂，是人类GIP激素的合成肽类似物。Tirzepatide 具有神经保护活性，可以用于预防和治疗 2 型糖尿病和肥胖症。
T4635	Ralinepag APD811	Others; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Others
	Ralinepag (APD811) 是一种可口服的非前列腺素前列环素 (IP) 受体激动剂，对人和大鼠 IP 受体以及人 DP1 受体的 EC50 分别为 8.5、530 和 850 nM。
T8682	Vazegepant hydrochloride Vazegepant HCl	CGRP Receptor	GPCR/G Protein; Neuroscience
	Vazegepant hydrochloride (Vazegepant HCl) 是一种用于偏头痛的鼻用 gepant，是一种高度亲和性CGRP 受体拮抗剂 (hCGRPKi=0.023 nM)。它可能有助于有效管理 COVID-19 相关肺部炎症。
T3548	Epacadostat INCB 024360,艾卡哚司他,IDO Inhibitor 1	IDO; Indoleamine 2,3-Dioxygenase (IDO)	Metabolism
	Epacadostat (INCB 024360) 是选择性的IDO1抑制剂，IC50=71.8 nM。
T27635	Isoxepac 伊索克酸,Olopatadine USP Related Compound C	Others	Others
	Isoxepac (Olopatadine USP Related Compound C) 是非甾体抗炎剂，显示出抗炎、镇痛和解热活性，已在多种动物模型中进行了相关研究。
TP1111	Tirzepatide LY-3298176	Glucagon Receptor	GPCR/G Protein
	Tirzepatide (LY-3298176) 是葡萄糖依赖性多肽 (GIP) 和胰高血糖素样肽-1 (GLP-1) 受体双重激动剂，具有神经保护活性，可改善血压并降低低密度脂蛋白（LDL）胆固醇和甘油三酯，可以用于研究糖尿病和肥胖症。
T6549	Isepamicin sulfate Isepamicine (Isepamycin,硫酸异帕米星,Isepamicin Sulphate,Isepacin,sch21420) Sulphate	Antibacterial; Antibiotic	Microbiology/Virology
	Isepamicin sulfate (sch21420) Sulphate) 是一种广谱氨基糖苷类抗生素，对产生 I 型 6-乙酰转移酶的菌株具有良好的活性，通过靶向细菌 30S 核糖体亚基来抑制细菌蛋白质合成。
T28607	Rocepafant LAU 8080,LAU8080,BN 50730,LAU-8080,BN50730,BN-50730	Platelet aggregation	Others
	Rocepafant (LAU8080) 是一种血小板活化因子(PAF)拮抗剂，可减轻新生大鼠缺氧缺血性脑损伤。Rocepafant 抑制肿瘤坏死因子-Afa 介导的小鼠 L929 肿瘤细胞的细胞毒性。
TP1111L	Tirzepatide Acetate(2023788-19-2 free base)	Glucagon Receptor	GPCR/G Protein
	Tirzepatide Acetate(2023788-19-2 free base) 是一种双重 GIP / GLP-1 受体激动剂。
TP1050L	Murepavadin acetate(944252-63-5 free base)	Antibacterial; Antibiotic	Microbiology/Virology
	Murepavadin acetate(944252-63-5 free base) 是一种有效且特异性的抗生素，用于治疗由铜绿假单胞菌引起的细菌感染。 Murepavadin acetate 靶向脂多糖转运蛋白 D。
T4610	Rimegepant BMS 927711,BMS-927711,BMS927711,BHV-3000	CGRP Receptor	GPCR/G Protein; Neuroscience
	Rimegepant (BMS 927711) 是一种有效的降钙素基因相关肽 (CGRP) 受体拮抗剂，其 Ki=0.027 nM，IC50=0.14 nM。
T2111	Sepantronium bromide YM155	Survivin; Autophagy	Apoptosis; Autophagy
	Sepantronium bromide (YM155) 是一种小分子促凋亡剂，具有潜在抗肿瘤活性。它是一种生存素抑制剂，IC50为 0.54 nM。
T16411	Otenzepad AF-DX 116	AChR	Neuroscience
	Otenzepad (AF-DX 116) 是 M2 mAChR 的特异性拮抗剂，对大鼠心脏和兔外周肺的 IC50 分别为 386 nM 和 640 nM。
T11212	EPAC 5376753 5-{[5-(2,4-dichlorophenyl)furan-2-yl]methylidene}-2-thioxodihydropyrimidine-4,6(1H,5H)-dione	cAMP	GPCR/G Protein
	EPAC 5376753 是 EPAC1 的变构抑制剂，在瑞士 3T3 细胞中的 IC50 为 4 µM。
T0368	Cinepazide maleate 马来酸桂哌齐特,MD-67350,Vasodistal,Brendil	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Cinepazide maleate (MD-67350) 是哌嗪衍生物，是一种钙通道阻滞剂，也是一种强效血管扩张剂，可用于脑血管疾病的研究，如缺血性中风和脑梗塞等。
T16040	Mepazine 甲哌啶嗪,Pecazine	Apoptosis; MALT	Apoptosis; Immunology/Inflammation
	Mepazine (Pecazine) 是一种有效的特异性 MALT1 抑制剂。 Mepazine 抑制 GSTMALT1 全长和 GSTMALT1 325-760，IC50 为 0.83 μM 和 0.42 μM。 Mepazine 增强细胞凋亡并影响细胞活力。
T4163	Reparixin DF 1681Y,Repertaxin,瑞帕利辛	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	Reparixin (Repertaxin) 是两种 CXCL8 受体 CXCR1/2 的强效抑制剂，它对 CXCR2 介导的细胞迁移具有微弱的抑制作用，IC50为 100 nM。它强烈阻断 CXCR1 介导的趋化性，IC50为 1 nM。
T1280	Nepafenac AL 6515,AHR 9434,奈帕芬胺	COX	Immunology/Inflammation; Neuroscience
	Nepafenac (AHR 9434) 是一种非甾体抗炎药，可抑制COX-2，是Amfenac 的原药。
T12293L	Olcegepant BIBN-4096,BIBN 4096BS	CGRP Receptor	GPCR/G Protein; Neuroscience
	Olcegepant (BIBN-4096) 是一种选择性的降钙素基因相关肽1 (CGRP1) 受体拮抗剂，IC50=0.03 nM，Ki=14.4 pM。
T9445	Vepafestinib	c-RET	Apoptosis; Tyrosine Kinase/Adaptors
	Vepafestinib 是 RET 的抑制剂，具有潜在的抗癌活性。
T1458	Epalrestat ONO2235,依帕斯他,依帕司他	Reductase	Endocrinology/Hormones; Metabolism
	Epalrestat (ONO2235) 是醛糖还原酶抑制剂，在长期治疗中具有良好的耐受性。它可以有效改善糖尿病神经病变的相关症状并延缓疾病的进展，特别是在微血管病变有限且血糖控制良好的患者中。
T17194	Ubrogepant MK-1602	CGRP Receptor	GPCR/G Protein; Neuroscience
	Ubrogepant (MK-1602) 是新型的、口服有效的降钙素基因相关肽受体拮抗剂。Ubrogepant 有潜力用于急性偏头痛的相关研究。
T1088	Repaglinide AG-EE 388 ZW,AG-EE 623ZW,瑞格列奈	Potassium Channel; PPAR	DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism
	Repaglinide (AG-EE 623ZW) 是一种能够用于2 型糖尿病的胰岛素促分泌剂。
T6531	Heparin sodium salt 肝素钠,Sodium heparinate,Heparin sodium	Factor Xa; Thrombin; Autophagy	Autophagy; Metabolism; Proteases/Proteasome
	Heparin sodium salt (Sodium heparinate) 是一种抗凝剂，可与抗凝血酶 III 可逆地结合，使凝血酶因子 IIa 和 Xa 的失活速度加快，显着抑制外泌体-细胞相互作用。
T64262	Heparin Lithium salt
	Heparin Lithium salt 是一种抗凝剂，能够可逆的结合抗凝血酶III (ATIII)。Heparin Lithium salt 明显阻碍外泌体-细胞相互作用。
T31996	Grepafloxacin Hydrochloride DSSTox_CID_26692,OPC-17116,DSSTox_RID_81826,DSSTox_GSID_46692
	Grepafloxacin Hydrochloride is an antimicrobial agent, oral broad-spectrum fluoroquinolone. It is used to treat bacterial infections.
T33578	Naepaine hydrochloride
	Naepaine hydrochloride is a biochemical.
T27275	Epaminurad
	Epaminurad (UR-1102) 是一种口服有效的和选择性的URAT1(尿酸转运体 1) 抑制剂，其Ki 为 0.057 μM。Epaminurad 适度地抑制OAT1和OAT3(有机阴离子转运体)。Epaminurad 是一种促尿酸排泄剂。Epaminurad 可用于痛风和高尿酸血症的研究。
T30136	Armepavine hydrochloride, (+/-)- DL-Armepavine hydrochloride
	Armepavine hydrochloride, (+/-)- is a compound which has been shown to exert immunosuppressive effects on T lymphocytes and on lupus nephritic mice.
T35313	Zolazepam CI716,CI 716,CI-716,Flupyrazapon
	Zolazepam(CI 716) is a derivative of pyrazole and diazazone that is structurally related to benzodiazepines and is used in veterinary medicine as an anesthetic for a variety of animals.
T11608	Epanolol Visacor,ICI141292	Others	Others
	Epanolol is a potent β-adrenoceptor partial agonist with a greater affinity for β1- than β2-adrenoceptors.
T78326	Depatuxizumab ABT-806	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Depatuxizumab是一种具有血脑屏障穿透性(brain-penetrant)的人源化单克隆抗体，特异性针对表皮生长因子受体(EGFR)。该抗体能够抑制携带突变型EGFRvIII及野生型EGFR的异种移植瘤模型的生长，用于癌症研究领域。
T74573	Bezeparsen
	Bezeparsen 是一种 PCSK9 合成抑制剂。

化合物

Flurochloridone

Cat.No: T20543

Synonym: 氟咯草酮,R 40244,R-40244,R40244,EPA Pesticide Chemical Code 128401

Target: Apoptosis, Reactive Oxygen Species

Cat.No: T20573

Synonym: Legurame,卡草胺,EPA Pesticide Chemical Code 259200,Carbetamid,11,561 RP,Carbetamex,Caswell No. 159B

Target: Others

Cat.No: T20669

Synonym: 苯达松,BAS 351-07H,EPA Pesticide Chemical Code 275200

Cat.No: T29000

Synonym: EPA Pesticide Chemical Code 121501,SAGA,HAG-107,HAG 107,Scout

Cat.No: T23768

Synonym: Caswell No. 206A,L 1058,L-1058,EPA Pesticide Chemical Code 206100,L1058

Cat.No: T24172

Synonym: NSC-190998,EPA Pesticide Chemical Code 309700,Nuvanol N,NSC190998,NSC 190998

Cat.No: T29981

Synonym: Caswell No. 005B,EPA Pesticide Chemical Code 128001,MON 4620,MON 4621,Limit

Cat.No: T71402

Itasetron hydrochloride monohydrate

Cat.No: T70804

Cat.No: T69692

Reparixin L-lysine salt

Cat.No: T12705

Synonym: REPERTAXIN L-赖氨酸盐,Repertaxin L-lysine salt

Target: CXCR

Cat.No: T3174

Synonym: CP-544326

Target: Prostaglandin Receptor

Cat.No: T16126

Synonym: AAD1566,PPL-1

Target: AChR

Cat.No: T1250

Synonym: Tiofosyl,Triethylenethiophosphoramide,三亚乙基硫代磷酰胺,Tiofosfamid

Target: DNA Alkylator/Crosslinker, DNA Alkylation, Antibacterial, Antibiotic

Cat.No: T12406

Target: iGluR

Cat.No: T15259

Synonym: CP-533536 free acid,2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸

Target: Prostaglandin Receptor

Cat.No: T24449

Synonym: Haffkinine,Erion

Target: Others

Tirzepatide sodium salt

Cat.No: TP1111L1

Synonym: LY-3298176 sodium salt,Tirzepatide sodium salt（2023788-19-2 free base）

Target: Glucagon Receptor

Cat.No: T4635

Synonym: APD811

Target: Others, Prostaglandin Receptor

Vazegepant hydrochloride

Cat.No: T8682

Synonym: Vazegepant HCl

Target: CGRP Receptor

Cat.No: T3548

Synonym: INCB 024360,艾卡哚司他,IDO Inhibitor 1

Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)

Cat.No: T27635

Synonym: 伊索克酸,Olopatadine USP Related Compound C

Target: Others

Cat.No: TP1111

Synonym: LY-3298176

Target: Glucagon Receptor

Isepamicin sulfate

Cat.No: T6549

Synonym: Isepamicine (Isepamycin,硫酸异帕米星,Isepamicin Sulphate,Isepacin,sch21420) Sulphate

Target: Antibacterial, Antibiotic

Cat.No: T28607

Synonym: LAU 8080,LAU8080,BN 50730,LAU-8080,BN50730,BN-50730

Target: Platelet aggregation

Tirzepatide Acetate(2023788-19-2 free base)

Cat.No: TP1111L

Target: Glucagon Receptor

Murepavadin acetate(944252-63-5 free base)

Cat.No: TP1050L

Target: Antibacterial, Antibiotic

Cat.No: T4610

Synonym: BMS 927711,BMS-927711,BMS927711,BHV-3000

Target: CGRP Receptor

Sepantronium bromide

Cat.No: T2111

Synonym: YM155

Target: Survivin, Autophagy

Cat.No: T16411

Synonym: AF-DX 116

Target: AChR

Cat.No: T11212

Synonym: 5-{[5-(2,4-dichlorophenyl)furan-2-yl]methylidene}-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

Target: cAMP

Cinepazide maleate

Cat.No: T0368

Synonym: 马来酸桂哌齐特,MD-67350,Vasodistal,Brendil

Target: Calcium Channel

Cat.No: T16040

Synonym: 甲哌啶嗪,Pecazine

Target: Apoptosis, MALT

Cat.No: T4163

Synonym: DF 1681Y,Repertaxin,瑞帕利辛

Target: CXCR

Cat.No: T1280

Synonym: AL 6515,AHR 9434,奈帕芬胺

Target: COX

Cat.No: T12293L

Synonym: BIBN-4096,BIBN 4096BS

Target: CGRP Receptor

Cat.No: T9445

Target: c-RET

Cat.No: T1458

Synonym: ONO2235,依帕斯他,依帕司他

Target: Reductase

Cat.No: T17194

Synonym: MK-1602

Target: CGRP Receptor

Cat.No: T1088

Synonym: AG-EE 388 ZW,AG-EE 623ZW,瑞格列奈

Target: Potassium Channel, PPAR

Heparin sodium salt

Cat.No: T6531

Synonym: 肝素钠,Sodium heparinate,Heparin sodium

Target: Factor Xa, Thrombin, Autophagy

Heparin Lithium salt

Cat.No: T64262

Grepafloxacin Hydrochloride

Cat.No: T31996

Synonym: DSSTox_CID_26692,OPC-17116,DSSTox_RID_81826,DSSTox_GSID_46692

Naepaine hydrochloride

Cat.No: T33578

Cat.No: T27275

Armepavine hydrochloride, (+/-)-

Cat.No: T30136

Synonym: DL-Armepavine hydrochloride

Cat.No: T35313

Synonym: CI716,CI 716,CI-716,Flupyrazapon

Cat.No: T11608

Synonym: Visacor,ICI141292

Target: Others

Cat.No: T78326

Synonym: ABT-806

Target: EGFR

Cat.No: T74573

Cat. No.	Product Name	Target	Signaling Pathways
T7068	Eicosapentaenoic acid ethyl ester Icosapent ethyl,顺-二十碳五烯酸乙酯,EPA ethyl ester,Ethyl eicosapentaenoate	Others; Endogenous Metabolite	Metabolism; Others
	Eicosapentaenoic acid ethyl ester (Ethyl eicosapentaenoate) 是一种ω-3 脂肪酸剂和人内源性代谢物。
T72152	Eicosapentaenoic Acid sodium 二十碳五烯酸钠盐,Timnodonic acid sodium,EPA sodium
	Eicosapentaenoic Acid (EPA) sodium 为口服活性 ω-3 长链多不饱和脂肪酸 (ω-3 LC-PUFAs)。其通过DNA去甲基化，促进肿瘤抑制基因CCAAT/增强子结合蛋白δ (C/EBPδ)的重新表达，并通过H-RAS内含子1 CpG岛的去甲基化，激活U937白血病细胞中RAS/ERK/C/EBPβ途径。此外，该化合物能够促进血管平滑肌细胞松弛和血管舒张。
T5368	Eicosapentaenoic Acid	Histone Demethylase; Others; Endogenous Metabolite	Chromatin/Epigenetic; Metabolism; Others
	Eicosapentaenoic Acid 是一种 ω-3 脂肪酸。
T75675	Nepasaikosaponin K	Antiviral	Immunology/Inflammation
	Nepasaikosaponin K 是一种从柴胡根中分离出来小分子化合物，具有抗流感和抗病毒活性，可用于研究病毒感染。
T19355	Heparan Sulfate 硫酸乙酰肝素,硫酸类肝素	FGFR; Wnt/beta-catenin; Endogenous Metabolite	Angiogenesis; Cytoskeletal Signaling; Metabolism; Stem Cells; Tyrosine Kinase/Adaptors
	Heparan sulfate 是一种复杂的线性多糖。Heparan sulfate 作为硫酸乙酰肝素蛋白聚糖的一部分出现，在细胞外基质和细胞表面表达丰富。
T38815	Millepachine	Apoptosis	Apoptosis
	Millepachine 是分离自中草药Millettia pachycarpaBenth 的查尔酮，在体内外对多种人类癌细胞均显示出强大的抗增殖作用。
TN4664	Norarmepavine	Others	Others
	N-norarmepavine shows significant cytotoxic activities against HL-60 carcinoma cell line with inhibitory ratios of 51.43% at concentration of 1 x 10(-5) M. Norarmepavine shows inhibition against Trypanosoma cruzi. D-(+)- N-norarmepavine exhibits significa
T3775	Armepavine 亚美罂粟碱,R-Armepavine,(-)-Armepavine	IκB/IKK; NF-κB	NF-κB
	Armepavine (R-Armepavine) 是来自Nelumbo nucifera 的活性化合物，能够抑制 TNF-α 诱导的MAPK 和NF-κB 信号级联反应。它不仅对人外周血单核细胞具有抗炎作用，且对 T 淋巴细胞和狼疮肾炎小鼠也具有免疫抑制作用。
T83463	11(α)-Hydroxynepasaikosaponin k
	11(α)-Hydroxynepasaikosaponin k（HOSSc）是B. scorzonerifolium Willd中的一种柴胡皂苷。
T20654	Heparin Certoparin,Bemiparin,Dalteparin,Adomiparin	Thrombin; Endogenous Metabolite; Antibacterial; Autophagy	Autophagy; Metabolism; Microbiology/Virology; Proteases/Proteasome
	Heparin (Adomiparin) 是硫酸粘多糖，常在临床医学上当抗凝剂使用。Heparin 在体内实验中显示出部分抗炎活性。
T80778	weak Hepatoprotective agent-1
	Weak Hepatoprotective agent-1 (Compound 11)，一种从Arctium lappa L. 分离得到的天然产物，在10 μM浓度下具有弱肝保护活性。
T3746	Dimethyl phthalate 邻苯二甲酸二甲酯,Solvanom,Avolin,Fermine,避蚊酯	Others	Others
	Dimethyl phthalate (Fermine) 是一种邻苯二甲酸酯 (PAEs)，是一种已知的内分泌干扰物，也是一种普遍存在的污染物。它常作为增塑剂，赋予硬质聚氯乙烯 (PVC) 树脂以柔韧性。

天然产物

Eicosapentaenoic acid ethyl ester

Cat.No: T7068

Synonym: Icosapent ethyl,顺-二十碳五烯酸乙酯,EPA ethyl ester,Ethyl eicosapentaenoate

Target: Others, Endogenous Metabolite

Eicosapentaenoic Acid sodium

Cat.No: T72152

Synonym: 二十碳五烯酸钠盐,Timnodonic acid sodium,EPA sodium

Eicosapentaenoic Acid

Cat.No: T5368

Target: Histone Demethylase, Others, Endogenous Metabolite

Nepasaikosaponin K

Cat.No: T75675

Target: Antiviral

Heparan Sulfate

Cat.No: T19355

Synonym: 硫酸乙酰肝素,硫酸类肝素

Target: FGFR, Wnt/beta-catenin, Endogenous Metabolite

Cat.No: T38815

Target: Apoptosis

Cat.No: TN4664

Target: Others

Cat.No: T3775

Synonym: 亚美罂粟碱,R-Armepavine,(-)-Armepavine

Target: IκB/IKK, NF-κB

11(α)-Hydroxynepasaikosaponin k

Cat.No: T83463

Cat.No: T20654

Synonym: Certoparin,Bemiparin,Dalteparin,Adomiparin

Target: Thrombin, Endogenous Metabolite, Antibacterial, Autophagy

weak Hepatoprotective agent-1

Cat.No: T80778

Dimethyl phthalate

Cat.No: T3746

Synonym: 邻苯二甲酸二甲酯,Solvanom,Avolin,Fermine,避蚊酯

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01107	TIMP-1 Protein, Human, Recombinant EPO,TIMP metallopeptidase inhibitor 1,TIMP-1,HCI,CLGI,TIMP,<...	Human	HEK293 Cells
	TIMP-1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21 kDa and the accession number is P01033.
TMPY-00154	TIMP-1 Protein, Human, Recombinant (hFc) TIMP-1,TIMP metallopeptidase inhibitor 1,EPA,EPO,CL...	Human	HEK293 Cells
	TIMP-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is P01033.
TMPY-00932	TIMP-1 Protein, Human, Recombinant (His) CLGI,EPA,TIMP,TIMP-1,EPO,TIMP metallopeptidase inhi...	Human	HEK293 Cells
	TIMP-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is P01033.
TMPY-01485	TIMP-1 Protein, Mouse, Recombinant Timp,EPA,Clgi,TIMP-1,TPA-S1,TIMP metallopeptidase i...	Mouse	HEK293 Cells
	TIMP-1 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21 kDa and the accession number is P12032.
TMPK-00093	TIMP-1 Protein, Mouse, Recombinant (hFc) TPA-S1,CLGI,TIMP-1,EPO,TIMP,EPA,EPATIMP-1,...	Mouse	HEK293 Cells
	Tissue inhibitor of metalloprotease-1 (TIMP-1) is a tissue inhibitor of matrix metalloproteinases (MMPs). It however exerts multiple effects on biological processes, such as cell growth, proliferation, differentiation and apoptosis, in an MMP-independent manner.
TMPY-05822	Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (His)	HBV-D	E. coli
	Hepatitis B virus (HBV) capsid assembly is a critical step in the propagation of the virus and is mediated by the core protein. The first cytoplasmic step in the formation of an infectious HBV virion is the formation of a capsid containing pregenomic RNA (pgRNA) and the viral polymerase (Pol). HBV capsid assembly is an attractive target for new antiviral therapies.
TMPY-05166	Hepatitis C virus (HCV) (serotype 1b, isolate HC-J4) Envelope/E2 Protein (His) HCV-1a E2	HCV	HEK293 Cells
	Hepatitis C virus (HCV) (serotype 1b, isolate HC-J4) Envelope/E2 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.4 kDa and the accession number is AAC15723.1.
TMPY-00323	Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST) NS3	HCV	E. coli
	HCV NS3 displays three enzymatic activities: serine protease, NTPase, and RNA helicase. HCV NS3 serine protease, in association with NS4A, is responsible for the cleavages of NS3-NS4A, NS4A-NS4B, NS4B-NS5A, and NS5A-NS5B. HCV NS3 RNA helicase binds to RNA and unwinds dsRNA in the 3' to 5' direction, and likely RNA stable secondary structure in the template strand (By similarity). Cleaves and inhibits the host antiviral protein MAVS. NS3/NS4A complex also prevents phosphorylation of human IRF3, t...
TMPH-00810	Hepatitis delta virus genotype I (HDV) Large delta antigen Protein (His & Myc)	HDV	P. pastoris (Yeast)
	Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal. Needs co-infection with hepatitis B virus to provide surface proteins, otherwise there is no packaging or budding. Packages the HDV ribonucleoprotein in hepatitis B virus empty particles. Interacts with both HDV genomic RNA and cytoplasmic tail of HBsAg. May inhibit viral RNA replication. Hepatitis delta virus genotype I (HDV) Large delta antigen Protein (His & Myc) is expressed i...
TMPY-00419	HEPACAM Protein, Human, Recombinant (His) HEPACAM,MLC2A,hepatic and glial cell adhes...	Human	HEK293 Cells
	HEPACAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.5 kDa and the accession number is Q14CZ8-1.
TMPH-03617	Miraculin Protein, Synsepalum dulcificum, Recombinant (His)	Synsepalum dulcificum	P. pastoris (Yeast)
	Miraculin has the property of modifying a sour taste into a sweet taste. This alteration of taste perception persists for many minutes. Miraculin Protein, Synsepalum dulcificum, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 23.4 kDa and the accession number is P13087.
TMPH-00528	Recombination and repair protein Protein, Enterobacteria phage T4, Recombinant (His)	Enterobacteria phage T4	E. coli
	Important in genetic recombination, DNA repair, and replication. Possesses pairing and strand-transfer activity. Interacts with dda and gene 32 proteins.
TMPY-04135	Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His) HCV-E1	HCV	HEK293 Cells
	Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.7 kDa and the accession number is AAC15725.1.
TMPH-00812	Hepatitis E virus genotype 1 (HEV-1) Protein ORF3 (His & SUMO)	HEV-1	E. coli
	Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. Acts also as a viroporin and forms ion conductive pores allowing viral particle release. Impairs the generation of type I interferon by downregulating host TLR3 and TLR7 as well as their downstream signaling pathways. Hepatitis E virus genotype 1 (HEV-1) Protein ORF3 (His & SUMO) is...
TMPY-00296	Hepatitis C virus (HCV) (serotype 1c,isolate HC-G9) E2 Protein (His) HCV-1a E2	HCV	HEK293 Cells
	Hepatitis C virus (HCV) (serotype 1c,isolate HC-G9) E2 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.2 kDa and the accession number is BAA03581.1.
TMPH-00811	Hepatitis delta virus genotype I (HDV) Small delta antigen Protein (His & Myc)	HDV	P. pastoris (Yeast)
	Promotes both transcription and replication of genomic RNA. Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal. May interact with host RNA polymerase II thereby changing its template requirement from DNA to RNA. RNA pol II complex would then acts as an RNA-directed RNA polymerase, and transcribe and replicate HDV genome. Hepatitis delta virus genotype I (HDV) Small delta antigen Protein (His & Myc) is expressed in yeast with N-6xHi...
TMPH-00814	Hepatitis E virus genotype 3 (HEV-3) Capsid protein (His)	HEV-3	P. pastoris (Yeast)
	Major viral capsid protein that encapsidates the viral genome. Binds to the 5' end of the genomic RNA. Hepatitis E virus genotype 3 (HEV-3) Capsid protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 29.3 kDa and the accession number is Q9YLQ9.
TMPH-00809	Hepatitis C Genome polyprotein (His)	HCV	E. coli
	Hepatitis C Genome polyprotein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 71.3 kDa and the accession number is S4UAW6.
TMPY-03068	HEPACAM2 Protein, Rat, Recombinant (His) HEPACAM family member 2,HepaCAM2	Rat	HEK293 Cells
	HEPACAM2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.7 kDa and the accession number is B5DEN8.
TMPH-03616	Miraculin Protein, Synsepalum dulcificum, Recombinant (E. coli, His)	Synsepalum dulcificum	E. coli
	Miraculin has the property of modifying a sour taste into a sweet taste. This alteration of taste perception persists for many minutes. Miraculin Protein, Synsepalum dulcificum, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 24.9 kDa and the accession number is P13087.
TMPH-00813	Hepatitis E virus genotype 1 (HEV-1) Secreted protein ORF2 (His)	HEV-1	Baculovirus Insect Cells
	Plays a role in the inhibition of host antibody-mediated neutralization without blocking viral cell entry.; Forms an icosahedral capsid with a T=1 symmetry and a 34 nm diameter. The capsid is composed of 60 copies linked to each other. Binds to the 5' end of the genomic RNA to mediate genome encapsidation. Binds to heparin surface proteoglycans (HSPGs) to mediate viral entry. Additionally, the interactions with host ASGR1 and ASGR2 facilitate viral infection of hepatocytes. Hepatitis E virus gen...
TMPY-01564	Hepatitis C virus (HCV-1a) E2 Protein (His) HCV-1a E2	HCV	HEK293 Cells
	Hepatitis C virus (HCV-1a) E2 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32 kDa and the accession number is NP_751921.1.
TMPY-03586	HEPACAM2 Protein, Rat, Recombinant (hFc) HepaCAM2,HEPACAM family member 2	Rat	HEK293 Cells
	HEPACAM2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.3 kDa and the accession number is B5DEN8.

重组蛋白

TIMP-1 Protein, Human, Recombinant

Cat.No: TMPY-01107

Species: Human

Expression System: HEK293 Cells

TIMP-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00154

Species: Human

Expression System: HEK293 Cells

TIMP-1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00932

Species: Human

Expression System: HEK293 Cells

TIMP-1 Protein, Mouse, Recombinant

Cat.No: TMPY-01485

Species: Mouse

Expression System: HEK293 Cells

TIMP-1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00093

Species: Mouse

Expression System: HEK293 Cells

Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (His)

Cat.No: TMPY-05822

Species: HBV-D

Expression System: E. coli

Hepatitis C virus (HCV) (serotype 1b, isolate HC-J4) Envelope/E2 Protein (His)

Cat.No: TMPY-05166

Species: HCV

Expression System: HEK293 Cells

Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST)

Cat.No: TMPY-00323

Species: HCV

Expression System: E. coli

Hepatitis delta virus genotype I (HDV) Large delta antigen Protein (His & Myc)

Cat.No: TMPH-00810

Species: HDV

Expression System: P. pastoris (Yeast)

HEPACAM Protein, Human, Recombinant (His)

Cat.No: TMPY-00419

Species: Human

Expression System: HEK293 Cells

Miraculin Protein, Synsepalum dulcificum, Recombinant (His)

Cat.No: TMPH-03617

Species: Synsepalum dulcificum

Expression System: P. pastoris (Yeast)

Recombination and repair protein Protein, Enterobacteria phage T4, Recombinant (His)

Cat.No: TMPH-00528

Species: Enterobacteria phage T4

Expression System: E. coli

Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His)

Cat.No: TMPY-04135

Species: HCV

Expression System: HEK293 Cells

Hepatitis E virus genotype 1 (HEV-1) Protein ORF3 (His & SUMO)

Cat.No: TMPH-00812

Species: HEV-1

Expression System: E. coli

Hepatitis C virus (HCV) (serotype 1c,isolate HC-G9) E2 Protein (His)

Cat.No: TMPY-00296

Species: HCV

Expression System: HEK293 Cells

Hepatitis delta virus genotype I (HDV) Small delta antigen Protein (His & Myc)

Cat.No: TMPH-00811

Species: HDV

Expression System: P. pastoris (Yeast)

Hepatitis E virus genotype 3 (HEV-3) Capsid protein (His)

Cat.No: TMPH-00814

Species: HEV-3

Expression System: P. pastoris (Yeast)

Hepatitis C Genome polyprotein (His)

Cat.No: TMPH-00809

Species: HCV

Expression System: E. coli

HEPACAM2 Protein, Rat, Recombinant (His)

Cat.No: TMPY-03068

Species: Rat

Expression System: HEK293 Cells

Miraculin Protein, Synsepalum dulcificum, Recombinant (E. coli, His)

Cat.No: TMPH-03616

Species: Synsepalum dulcificum

Expression System: E. coli

Hepatitis E virus genotype 1 (HEV-1) Secreted protein ORF2 (His)

Cat.No: TMPH-00813

Species: HEV-1

Expression System: Baculovirus Insect Cells

Hepatitis C virus (HCV-1a) E2 Protein (His)

Cat.No: TMPY-01564

Species: HCV

Expression System: HEK293 Cells

HEPACAM2 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-03586

Species: Rat

Expression System: HEK293 Cells

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