103
87
1
27
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
CL0093 |
PARP inhibitor kit
PARP inhibitor kit |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14322 |
ARP-100
MMP-2 Inhibitor III |
MMP | Proteases/Proteasome |
ARP-100 (MMP-2 Inhibitor III) 是选择性基质金属蛋白酶MMP-2抑制剂 (IC50=12 nM)。它对 MMP-1 (>50 μM),MMP-3 (4.5 μM),MMP-7 (>50 μM) 和MMP-9 (0.2 μM) 的抑制活性较小。它与 MMP-2 的 S1'口袋相互作用,并在体外对基质胶的侵袭模型中显示抗侵袭特性。 | |||
T22034 |
ARP 101
|
||
ARP101 是一种有效的选择性基质金属蛋白酶-2 (MMP-2)抑制剂,在癌细胞中诱导自噬相关的细胞死亡。ARP101可有效诱导自噬体形成和LC3I 转化为LC3II。 | |||
T72437 |
PARP1/2/TNKS1/2-IN-1
|
Apoptosis; PARP; Wnt/beta-catenin | Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Stem Cells |
PARP1/2/TNKS1/2-IN-1 是一种多靶点抑制剂,抑制 PARP-1、PARP-2、TNKS1 和 TNKS2 。PARP1/2/TNKS1/2-IN-1 具有潜在的抗肿瘤活性,可诱导细胞凋亡。 | |||
T62281 |
PARP-1-IN-2
|
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
PARP-1-IN-2 是一种有效且可透过血脑屏障的 PARP1 抑制剂(IC50: 149 nM)。PARP-1-IN-2 在细胞实验中对人肺腺癌上皮细胞系 A549 显示出显著的抗增殖活性。PARP-1-IN-2 可诱导 A549 细胞凋亡。 | |||
T1325 |
Carprofen
卡洛芬,Ridamyl,Imadyl,Rimadyl |
FAAH; COX; Autophagy | Autophagy; Immunology/Inflammation; Metabolism; Neuroscience |
Carprofen (Ridamyl) 是多靶点FAAH/COX 抑制剂,能够抑制 COX-2,COX-1 和 FAAH 的活性,IC50值分别为 3.9 μM,22.3 μM 和 78.6 μM。它是一种丙酸衍生物和非甾体抗炎药,具有抗炎、镇痛和解热活性。 | |||
TP1220L |
Carperitide acetate
醋酸卡培立肽,Carperitide acetate (89213-87-6 Free base),Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate |
Endothelin Receptor | GPCR/G Protein |
Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate) 是一种由 28 个氨基酸组成的激素,由心脏产生并分泌,以响应心脏损伤和机械拉伸。Carperitide acetate 抑制内皮素-1 (endothelin-1) 分泌。 | |||
T9610 |
PARP1-IN-5 dihydrochloride
|
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
PARP1-IN-5 dihydrochloride 是一种具有口服活性的有效选择性 PARP-1 抑制剂 (IC50 =14.7 nM)。它可用于癌症的研究。 | |||
T68036 |
Carprazidil
|
Others | Others |
Carprazidil 是一种强效的血管扩张剂,可用于治疗严重高血压和轻度心力衰竭。 | |||
T72553 |
ARTD10/PARP10-IN-1
|
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
ARTD10/PARP10-IN-1 是一种强效性的 PARP 抑制剂,抑制单 ADP 核糖转移酶 ARTD7/PARP15,ARTD8/PARP14,ARTD10/PARP10 和聚 ADP-核糖聚合酶-1 (ARTD1/PARP1),具有潜在的抗癌抗肿瘤活性,可用于研究前列腺癌和乳腺癌。 | |||
T12365 |
PARP/PI3K-IN-1
|
PARP; PI3K | Chromatin/Epigenetic; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling |
PARP/PI3K-IN-1 是一种 新型双重聚(ADP-核糖)聚合酶(PARP)和磷酸肌醇 3-激酶(PI3K)双重抑制剂,具有抗癌、抗肿瘤和抗癌细胞增殖活性,可用于研究乳腺癌、胰腺癌和肺癌。 | |||
T4978 |
Sarpogrelate hydrochloride
盐酸沙格雷酯,MCI-9042 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Sarpogrelate hydrochloride (MCI-9042) 是一种选择性5-HT2R 拮抗剂,可用于研究与血栓形成有关的血管疾病,对 5-HT2A、5-HT2B 和 5-HT2C 受体的pKi 值分别为 8.52、6.57 和 7.43。 | |||
T9517 |
Arprinocide
|
Others | Others |
Arprinocide 是一种次黄嘌呤-鸟嘌呤转运抑制剂。 | |||
T67932 |
PARP10-IN-3
|
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
PARP10-IN-3 是一种有效且具有选择性的单-ADP-核糖基转移酶 PARP10 抑制剂,对人 PARP10 具有抑制作用( IC50 :480 nM)。PARP10-IN-3 对人 PARP2 和 人 PARP15也具有抑制作用, IC50 值都是 1.7 μM。 | |||
T9891 |
PARP1-IN-8
N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide |
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
PARP1-IN-8 (N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide) 是PARP1的有效抑制剂(IC50 = 97 nM)。 | |||
T79600 |
Zharp2-1
|
RIP kinase | Apoptosis; NF-κB |
Zharp2-1是一种 RIPK2 抑制剂,抑制了 MDP 诱导或单核细胞增生李斯特菌感染诱导的炎症细胞因子的转录,缓解MDP诱导的小鼠腹膜炎症状,可用于研究炎症性肠病 (IBD)。 | |||
T78182 |
PARP-1-IN-4
|
Others; PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair; Others |
PARP-1-IN-4 是一种有效的 PARP-1抑制剂,具有潜在的看抗肿瘤活性,抑制 PARP-1 可用于癌症的发生。 | |||
T73007 |
PARP10-IN-2
|
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
PARP10-IN-2 是一种有效的单-ADP-核糖基转移酶 PARP10 抑制剂,对人 PARP10 的 IC50 值为 3.64 μM。PARP10-IN-2 对 PARP2 和 PARP15也具有抑制作用, IC50 分别为 27 μM 和 11 μM。 | |||
T73027 |
PARP-2-IN-3
|
Apoptosis; PARP | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair |
PARP-2-IN-3 作为一种强效 PARP-2 抑制剂(IC50=0.07 μM),具有抗肿瘤活性,能够诱导癌细胞凋亡(apoptosis)和坏死,可用于研究乳腺癌。 | |||
T78157 |
PARP-1-IN-3
|
Apoptosis; PARP | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair |
PARP-1-IN-3 是一种高效的 PARP-1 抑制剂,对 PARP-1 和 PARP-2 具有抑制作用, IC50 值分别为 0.25 nM 和 2.34 nM。PARP-1-IN-3 具有潜在的抗炎活性,促使细胞凋亡并使细胞周期停滞在 G2/M 期。PARP-1-IN-3 可用于研究与癌症相关的疾病。 | |||
T126028 | 8-O-4-Hydroxycinnamoylharpagide | ||
8-O-4-Hydroxycinnamoylharpagide 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126028,CAS号为 133645-37-1。 | |||
T60567 | PARP10/15-IN-2 | ||
PARP10/15-IN-2 (Compound 8h) 是 PARP10和 PARP15的双重抑制剂,IC50值分别为 0.15 μM 和 0.37 μM。PARP10/15-IN-2 可以进入细胞并使细胞免于凋亡。 | |||
T73025 | PARP7-IN-12 | ||
PARP7-IN-12 是一种有效的PARP7抑制剂,其IC50值为 7.836 nM。PARP7-IN-12 可用于癌症的研究。 | |||
T79405 |
PARP1-IN-15
|
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
PARP1-IN-15(Compound 6)是一款针对PARP1的抑制剂,能够抑制坦聚合酶(TNKS)并促进DNA双链断裂损伤。该化合物在诱导肿瘤细胞凋亡(apoptosis)方面具有显著作用,且在三阴性乳腺癌(TNBC)细胞及来源于TNBC患者的类器官中显示出抗癌活性,适用于探究BRCA1突变状态下的TNBC研究。 | |||
T79330 |
PARP-1-IN-13
|
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
PARP-1-IN-13 (Compound 19c) 为一种高效PARP-1抑制剂,其IC50值为26 nM。该化合物能够抑制DNA单链断裂修复并增强DNA双链断裂效应。此外,PARP-1-IN-13通过激活线粒体凋亡(apoptosis)途径来促进癌细胞死亡。 | |||
T12366 |
PARP14 inhibitor H10
|
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM | |||
T62508 |
PARP-1/2-IN-1
|
||
PARP-1/2-IN-1是一种有效的 PARP-1 (IC50: 0.51 nM) 和 PARP-2 (IC50: 23.11 nM) 抑制剂。 | |||
T124022 |
8-p-Coumaroylharpagide
|
||
T72554 |
ARTD10/PARP10-IN-2
|
||
ARTD10/PARP10-IN-2 是一种强效、非选择性的PARP 抑制剂。ARTD10/PARP10-IN-2 靶向单 ADP 核糖转移酶 (ARTD10/PARP10) 和聚 ADP-核糖聚合酶-1 (ARTD1/PARP1),IC50分别为 2.0 μM,和 9.7 μM。 | |||
T124648 |
Conocarpan
|
||
Conocarpan 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124648,CAS号为 56319-02-9。 | |||
T131593 |
Pterocarpin methylether
|
||
Pterocarpin methylether 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131593。 | |||
T10685L |
Carpaine hydrochloride
|
Others | Others |
Carpaine hydrochloride, an alkaloid isolated from Carica papaya Linn, has anti-thrombocytopenic activity. It has the anti-plasmodial activity to prevent malaria. | |||
T126206 |
Norartocarpanone
|
||
Norartocarpanone 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126206,CAS号为 121694-88-0。 | |||
T24597 |
PARPi-FL
Olaparib-bodipy FL,Olaparib bodipy FL |
||
PARPi-FL is an agent of fluorescent PARP imaging. In vitro, it is capable of detecting the target engagement of a PARP inhibitor panel. | |||
T81544 |
PARP1-IN-16
|
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
PARP1-IN-16(化合物12a)是一款高效的PARP1抑制剂,其IC50为1.89 nM。该化合物能够促使细胞周期在S期停滞,并引发HCT-116细胞的凋亡。 | |||
T40310 |
PARP/EZH2-IN-1
PARP/EZH2-IN-1 |
||
PARP/EZH2-IN-1 is a novel compound that functions as a dual inhibitor for both PARP (IC50 6.87 nM) and EZH2 (IC50 36.51 nM), showing promising potential for the treatment of triple-negative breast cancer with wild-type BRCA. | |||
T30141L |
Arpenal HCl
Arpenal hydrochloride |
||
Arpenal HCl is a ganglionic blocking agent which may be useful in the treatment of bronchial asthma. | |||
T131393 |
Condylocarpine
|
||
Condylocarpine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131393。 | |||
T63471 |
PARP1/BRD4-IN-1
|
||
PARP1/BRD4-IN-1 是高度选择性的 PARP1(IC50: 49 nM)和BRD4(IC50: 202 nM)的有效抑制剂。PARP1/BRD4-IN-1 能够抑制 PARP1 和 BRD4 的表达与活性,进而协同抑制胰腺癌细胞的恶性生长。 | |||
T33295 |
Mercarphon
AI327723,AI 3-27723 |
||
Mercarphon is a biochemical. | |||
T60637 |
PARP1-IN-11
|
||
PARP1-IN-11 (compound 49) 是一种有效的 PARP1抑制剂,其 IC50值为 0.082 μM,可完全抑制 PARP1,并显著抑制 PARP3、TNKS1 和 TNKS2。 | |||
T123950 |
9α-Hydroxysophocarpine
|
||
9α-Hydroxysophocarpine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T123950。 | |||
T69139 |
Thalicarpine
|
||
Thalicarpine is a natural aporphine benzylisoquinoline vinca alkaloid with antineoplastic activity. Thalicarpine binds to and inhibits p-glycoprotein, the multidrug resistance efflux pump. Thalicarpine also induces single-strand breaks in DNA and arrests cancer cells at the G2/M and G1 phase of the cell cycle. Check for active clinical trials or closed clinical trials using this agent. | |||
T32625 |
Leiocarposide
Lejokarpozyd |
||
Leiocarposide is a phenolic bisglucoside from Solidago virgaurea L. | |||
T81541 |
PARP7-IN-16
|
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
PARP7-IN-16是一种高效、选择性且具有口服生物活性的PARP-1/2/7抑制剂,其IC50分别为0.94 nM , 0.87 nM 和0.21 nM 。PARP7-IN-16适合用于乳腺癌与前列腺癌的研究。 | |||
T130140 |
Lecocarpinolide H
|
||
Lecocarpinolide H 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T130140。 | |||
T62540 | PARP1/BRD4-IN-2 | ||
PARP1/BRD4-IN-2 是一种有效的、选择性的 PARP1 (IC50: 197 nM) 和 BRD4 (IC50: 238 nM) 抑制剂。PARP1/BRD4-IN-2 能够抑制 DNA 损伤修复,阻滞 G0/G1 细胞周期转变,诱导细胞凋亡 (apoptosis)。PARP1/BRD4-IN-2 对 MDA-MB-468 小鼠异种移植瘤模型表现出抗肿瘤效果。PARP1/BRD4-IN-2 能够用于研究三阴性乳腺癌 (TNBC)。 | |||
T124691 | Calopocarpin | ||
Calopocarpin 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124691,CAS号为 53802-77-0。 | |||
T61798 | PARP-1-IN-1 | ||
PARP-1-IN-1 is a highly selective and orally active inhibitor of the enzyme PARP-1, with an IC50 value of 0.96 nM. It exhibits excellent tolerance and demonstrates significant activity in a single dose in the MDA-MB-436 xenotransplantation model [1]. | |||
T39139 |
PARP1-IN-6
PARP1-IN-6 |
||
PARP1-IN-6 is a dual tubulin/PARP-1 inhibitor with IC 50 values of 0.94 and 0.48 μM, respectively. | |||
T72397 |
PARP11 inhibitor ITK7
ITK7 |
||
PARP11 inhibitor ITK7 (ITK7) 为高效选择性的PARP11抑制剂,IC50为14 nM,主要用于针对PARP11的细胞定位研究。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0804 |
Pilocarpine Hydrochloride
NSC 5746 HCl,盐酸毛果芸香碱,Pilocarpine HCl,(+)-Pilocarpine hydrochloride |
AChR | Neuroscience |
Pilocarpine Hydrochloride (NSC 5746 HCl) 是一种 M3 型毒蕈碱乙酰胆碱受体激动剂,用于制作癫痫实验模型 | |||
TN1192 |
16-Epivoacarpine
|
Others | Others |
16-Epivoacarpine 是一种分离自 Gelsemium elegans 中的生物碱。 | |||
T2746 |
Sophocarpine monohydrate
槐果碱,Sophocarpine,槐果碱水合物 |
Apoptosis; Influenza Virus; Akt; PI3K; AMPK; Autophagy | Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling |
Sophocarpine monohydrate 是从传统草药苦参中提取的一种重要生物碱,具有抗肿瘤活性,可用于肝细胞癌,前列腺癌和结肠直肠癌。苦参具有抗病毒,抗肿瘤和抗炎等多种药理作用。 | |||
T6S2025 |
8-O-Acetylharpagide
8-O-乙酰哈巴苷,8-Acetylharpagide,3-Acetylharpagide,Acetylharpagide,8-O-Acetylharpagide |
Antibacterial | Microbiology/Virology |
8-O-Acetylharpagide 是从 Ajuga reptans 中分离得到的一种环烯醚萜,有抗肿瘤、抗病毒、抗菌和抗炎作用。它对豚鼠的离体平滑肌有生物活性。 | |||
T6S2024 |
Harpagide
|
Antibacterial; Parasite | Microbiology/Virology |
Harpagide 是从Scrophularia cryptophila 中分离出来的一种鸢尾糖苷,具有抗炎和抗寄生虫活性,对T.b. rhodesiense 具有体外锥虫杀虫活性,IC50为 21 μg/mL,它对L. donovani 的IC50值为 2.0 μg/mL。 | |||
T2786 |
Oxysophocarpine
氧化槐树碱,氧卡地平 |
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
Oxysophocarpine 是提取自海藻的生物碱。它抑制口腔鳞状细胞癌的生长和转移。它对中枢神经系统和周围神经系统具有神经保护作用和抗伤害感受作用。 | |||
T6677 |
Sophocarpine
|
ERK; p38 MAPK; NF-κB; TLR; COX; HER; JNK; STAT | Angiogenesis; Immunology/Inflammation; JAK/STAT signaling; MAPK; Neuroscience; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors |
Sophocarpine 是一种从传统草药苦参中提取的重要生物碱。苦参具有抗病毒、抗肿瘤和抗炎等多种药理作用。它通过多种机制显著抑制癌细胞的生长,具有抗肿瘤活性。 | |||
TQ0134 |
Podocarpusflavone A
|
Topoisomerase | DNA Damage/DNA Repair |
Podocarpusflavone A is a DNA topoisomerase I inhibitor. It has moderated anti-proliferative activity induce cell apoptosis in MCF-7. | |||
T1231 |
Pilocarpine nitrate
匹鲁卡品硝酸盐,Pilagan,硝酸毛果芸香碱,Pilofrin |
AChR | Neuroscience |
Pilocarpine nitrate (Pilagan) 是 M3 型毒蕈碱乙酰胆碱受体激动剂,可用于治疗青光眼。 | |||
T12514 |
Podocarpic acid
|
Others; TRP/TRPV Channel | Membrane transporter/Ion channel; Others |
Podocarpic acid 是一种天然产物,是一种新型 TRPA1 激活剂。 | |||
T13768 |
(+)-Medicarpin
|
Estrogen/progestogen Receptor | Endocrinology/Hormones |
(+)-Medicarpin, a pterocarpan, is an isoflavonoid compound derived from multiple medicinal plant species such as Sophora japonica, Zollernia paraensis, Platymiscium yucatamun, Machaerium aristulatum, and Platymiscium floribundum. It exhibits potent inhibition of osteoclastogenesis and facilitates bone healing and increased bone mass through osteoblast differentiation, which is mediated by the estrogen receptor (ER) β. | |||
T6S2023 |
Harpagoside
|
Others; COX; NO Synthase | Immunology/Inflammation; Neuroscience; Others |
Harpagoside 是从爪钩草中分离出来的一种天然产物,可抑制COX-1和COX-2活性,并抑制 NO 的产生。 | |||
T2972 |
Rutaecarpine
Rutacarpine,吴茱萸次碱,Rhetine,Rutecarpine |
COX | Immunology/Inflammation; Neuroscience |
Rutaecarpine (Rhetine) 是从槐木中提取的一种生物碱,是 COX-2的抑制剂,IC50值为0.28 μM。 | |||
T2S0142 |
4-Hydroxylonchocarpin
异补骨脂色烯查耳酮,Isobavachromene |
Others | Others |
Isobavachromene is a natural product from Psoralea corylifolia | |||
TN7235 |
4-methoxylonchocarpin
|
TNF; NF-κB | Apoptosis; NF-κB |
4-methoxylonchocarpin 是从Abrus precatorius 的根中分离出来的以一种有效的抗炎化合物。4-methoxylonchocarpin 通过抑制LPS 与巨噬细胞的TLR4结合来抑制NF-κB 激活TNF 表达,抑制TNBS 引起的小鼠结肠炎。 | |||
TN1918 |
Medicarpin
美迪紫檀素 |
Apoptosis; BCL; ROS; JNK | Apoptosis; Immunology/Inflammation; MAPK |
Medicarpin 是从紫花苜蓿中分离出的一种类黄酮。它通过调节 P-gp 介导的药物外流,诱导白血病 P388 细胞凋亡并克服多药耐药性。 | |||
TN1121 |
Evocarpine
|
Apoptosis; cAMP; Anti-infection; Calcium Channel; Antibacterial | Apoptosis; GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology |
Evocarpine 是从 Evodiae fructus 分离得到的一种喹诺酮类生物碱,有抗细菌活性。它可通过电压依赖性钙通道抑制 Ca2+内流。 | |||
TN3491 | Barpisoflavone A | Others | Others |
Barpisoflavone A possesses moderate estrogen partial agonistic activities and moderate antioxidant activities. | |||
TN6138 | Vesticarpan | ||
Vesticarpan 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6138,CAS号为 69853-46-9。 | |||
T72803 | Norartocarpetin | ||
Norartocarpetin 是一种酪氨酸酶抑制剂。Norartocarpetin 具有较强的酪氨酸酶抑制活性,其抑制活性 IC50值为 0.47 μM。Norartocarpetin 作为一种抗褐变剂可用于食品体系的研究。Norartocarpetin 对肺癌细胞 (NCI-H460) 也具有显著的抗癌活性,其 IC50值为 22 μM。Norartocarpetin 的抗增殖作用是通过靶向 Ras/Raf/MAPK 信号通路、线粒体介导的细胞凋亡、S 期细胞周期阻滞和抑制细胞迁移和侵袭实现的。 | |||
T72805 |
(±)-Hydnocarpin
|
||
(±)-Hydnocarpin 是一种黄酮木脂素。(±)-Hydnocarpin 可以抑制S. aureus 的生长,MIC50值为 3.1 μM。 | |||
TN4223 |
Homopterocarpin
|
Antifection | Microbiology/Virology |
Homopterocarpin and Pterocarpus extract offer gastroprotection against indomethacin- induced ulcer by antioxidative mechanism and the modulation of gastric homeostasis, homopterocarpin may be responsible for, or contribute to the antiulcerogenic property | |||
TN1321 |
6'-O-Cinnamoyl harpagide
6'-O-Cinnamoylharpagide,(1S,4AS,5R,7S,7AR)-1,4A,5,6,7,7A-六氢-4A,5,7-三羟基-7-甲基环戊二烯并[C]吡喃-1-基 BETA-D-吡喃葡萄糖苷 6-[(2E)-3-苯基-2-丙烯酸酯],6'-O-肉桂酰基哈巴苷,6'-O-肉桂酰哈巴苷 |
Others | Others |
6'-O-Cinnamoylharpagide has anti-inflammatory activity. | |||
T25634 |
Lasiocarpine N-oxide
4-21-00-02054 (Beilstein Handbook Reference) |
||
Lasiocarpine N-oxide is a natural compound found to be higher in many tea bags, herbal drugs and honey by mass spectrometry. | |||
TN3200 |
6alpha-Hydroxymedicarpin
|
Others | Others |
6alpha-Hydroxymedicarpin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3200,CAS号为 61135-92-0。 | |||
TN4483 |
Macrocarpal N
|
Others | Others |
Macrocarpal N是一种天然产物,属于桃金娘科桉属,其产品编号为 TN4483,CAS号为 221899-21-4。Macrocarpal N可用作对照参考。 | |||
TN3719 |
Cristacarpin
|
p38 MAPK; ROS; CDK; Antifection; p53 | Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation; MAPK; Microbiology/Virology |
Cristacarpin exhibits moderate but selective activity towards DNA repair-deficient yeast mutants. It promotes endoplasmic reticulum (ER) stress, leading to sub-lethal reactive oxygen species (ROS) generation and which eventually terminates by triggering s | |||
TN5604 |
Isodocarpin
Macrocalin A |
||
Isodocarpin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5604,CAS号为 10391-08-9。 | |||
T20617 |
Sarpagine
Raupin |
||
Sarpagine is an alkaloid with the antihypertonic effect. | |||
TN2953 |
3-Hydroxysarpagine
|
Topoisomerase | DNA Damage/DNA Repair |
3-Hydroxysarpagine是一种天然产物,属于夹竹桃科萝芙木属,其产品编号为 TN2953,CAS号为 857297-90-6。3-Hydroxysarpagine可用作对照参考。 | |||
T25653 |
Leiocarpaquinone
|
||
Leiocarpaquinone is a bioactive chemical from root of Uentilago leiocarpa Benth. (Rhamnaceae). | |||
TN2619 |
13-Oxopodocarp-8(14)-en-18-oic acid
|
Others | Others |
13-Oxopodocarp-8(14)-en-18-oic acid 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2619,CAS号为 63976-69-2。 | |||
TN3162 |
6-Epi-8-O-acetylharpagide
|
Others | Others |
6-Epi-8-O-acetylharpagide是一种天然产物,属于玄参科玄参属,其产品编号为 TN3162,CAS号为 97169-44-3。6-Epi-8-O-acetylharpagide可用作对照参考。 | |||
TN5035 | Sophoracarpan A | Others | Others |
Sophoracarpan A is a natural product from Sophora tomentosa L. | |||
TN2612 |
13-Hydroxy-8,11,13-podocarpatrien-18-oic acid
|
Others | Others |
13-Hydroxy-8,11,13-podocarpatrien-18-oic acid 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2612,CAS号为 61597-83-9。 | |||
TN4798 |
Piptocarphin A
|
Others | Others |
Piptocarphin A shows strong cytotoxic activity against mouse lymphoid tumor cell line P388 with the IC(50) value of 0.77 microM. | |||
TN4481 |
Macrocarpal K
|
Others | Others |
Macrocarpal K 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4481,CAS号为 218290-59-6。 | |||
TN5681 |
Cypellocarpin C
Camaldulenside,桉叶苷 |
||
Cypellocarpin C shows potent in vitro antitumor-promoting activity, it also can suppress an in vivo two-stage carcinogenesis induced with nitric oxide and TPA on mouse skin. | |||
TN4847 |
Pterocarpadiol A
|
Others | Others |
Pterocarpadiol A is a kind of very rare 6a,11b-dihydroxypterocarpan, and its presence as a marker may be helpful in chemotaxonomical classification. | |||
TN4849 |
Pterocarpadiol C
|
Others | Others |
Pterocarpadiol C is a kind of very rare 6a,11b-dihydroxypterocarpan, and its presence as a marker may be helpful in chemotaxonomical classification. | |||
TN1407 |
Artocarpin
|
Antibiotic | Microbiology/Virology |
Artocarpin 是一种从 Artocarpus heterophyllus 的木材中分离出来的黄酮类化合物,具有杀菌活性,抑制耐多药金黄色葡萄球菌和肠球菌属细菌。Artocarpin 可抑制 B16 黑色素瘤细胞中黑色素的生物合成,诱导快速细胞裂解。Artocarpin 可用于研究皮肤病。 | |||
TN5705 |
Muricarpone B
|
||
Muricarpone B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5705,CAS号为 886226-15-9。 | |||
TN5036 |
Sophoracarpan B
|
Others | Others |
Sophoracarpan B is a natural product from Sophora tomentosa L. | |||
T20524 |
Lasiocarpine
7-Angelyleuropine,(-)-Lasiocarpine,Europine 7-angelate,AI3-51770 |
||
Lasiocarpine is a pyrrolizidine alkaloid, it has acute cytotoxicity in human and hepatic cell lines. | |||
TN4479 |
Macrocarpal I
|
Antifection | Microbiology/Virology |
Macrocarpal I has anti-glucosyltransferase, and anti-bacterial activities. | |||
T83565 |
(2E)-Leocarpinolide F
|
||
(2E)-Leocarpinolide F(化合物20),为从Sigesbeckia orientalis中提取的香叶鹤型倍半萜。 | |||
TN3105 |
5-Dehydroxyparatocarpin K
|
Others | Others |
5-Dehydroxyparatocarpin K是一种天然产物,属于豆科补骨脂属,其产品编号为 TN3105,CAS号为 124858-37-3。5-Dehydroxyparatocarpin K可用作对照参考。 | |||
TN4310 | Isomedicarpin | Others | Others |
Isomedicarpin is a phytoalexin. | |||
TN4478 | Macrocarpal H | Antifection | Microbiology/Virology |
Macrocarpal H has anti-glucosyltransferase, and anti-bacterial activities. | |||
TN2944 |
3-Hydroxy-8,9-methylenedioxypterocarpene
|
Others | Others |
3-Hydroxy-8,9-methylenedioxypterocarpene 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2944,CAS号为 59901-98-3。 | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00028 |
ARMET/MANF Protein, Human, Recombinant (hFc)
ARP,ARMET,mesencephalic astrocyte-derived neurotrop... |
Human | HEK293 Cells |
ARMET/MANF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is A8K878. | |||
TMPY-05053 |
ANGPTL2 Protein, Human, Recombinant (His)
HARP,angiopoietin-like 2,ARP2 |
Human | HEK293 Cells |
ANGPTL2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.4 kDa and the accession number is A0A024R868. | |||
TMPY-01678 |
ARMET/MANF Protein, Human, Recombinant (His)
ARMET,mesencephalic astrocyte-derived neurotrophic factor, |
Human | HEK293 Cells |
ARMET/MANF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is P55145. | |||
TMPY-00358 |
Arp3/ACTR3 Protein, Human, Recombinant (His & GST)
ARP3,ARP3 actin-related protein 3 homolog ... |
Human | Baculovirus Insect Cells |
Arp3/ACTR3 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.1 kDa and the accession number is A0A024RAI1. | |||
TMPY-03523 |
ANGPTL4 Protein, Human, Recombinant (His)
NL2,HFARP,angiopoietin-like 4,ARP4,PGAR,FI... |
Human | HEK293 Cells |
ANGPTL4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.5 kDa and the accession number is Q9BY76. | |||
TMPK-00299 |
ANGPTL2 Protein, Human, Recombinant (His & Avi), Biotinylated
MGC8889,ANGRP2,angiopoietin-like 2,ANGPTL2,HARP, |
Human | HEK293 Cells |
Angiopoietin-like 2 (ANGPTL2) is a proinflammatory protein belonging to the angiopoietin-like family. ANGPTL2 is secreted and detected in the systemic circulation. Different observational clinical studies reported that circulating levels of ANGPTL2 increase significantly in various chronic inflammatory diseases and showed associations between ANGPTL2 levels and diagnosis and/or prognosis of cardiovascular diseases, diabetes, chronic kidney disease, and various types of cancers. ANGPTL2 Protein, ... | |||
TMPK-00298 |
ANGPTL2 Protein, Human, Recombinant (His & Avi)
ANGRP2,ANGPTL2,angiopoietin-like 2,HARP,MGC8889, |
Human | HEK293 Cells |
Angiopoietin-like 2 (ANGPTL2) is a proinflammatory protein belonging to the angiopoietin-like family. ANGPTL2 is secreted and detected in the systemic circulation. Different observational clinical studies reported that circulating levels of ANGPTL2 increase significantly in various chronic inflammatory diseases and showed associations between ANGPTL2 levels and diagnosis and/or prognosis of cardiovascular diseases, diabetes, chronic kidney disease, and various types of cancers. ANGPTL2 Protein, ... | |||
TMPY-02878 |
ANGPTL4 Protein, Human, Recombinant (hFc)
TGQTL,angiopoietin-like 4,pp1158,PGAR,ANGPTL2,NL2,ARP |
Human | HEK293 Cells |
ANGPTL4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 55.5 kDa and the accession number is Q9BY76. | |||
TMPK-01329 |
ANGPTL4 Protein, Cynomolgus, Recombinant (His)
PGAR,AGP4,NGPTL2,ANG4,ANGPTL4,pp1158,HFARP,ANG3,Ang... |
Cynomolgus | HEK293 Cells |
Candidates for this common regulatory system include signals mediated by peroxisome proliferator-activated regulator and its response factor, angiopoietin-like 4. The expression and bioactivity of angiopoietin-like 4, an adipocytokine that was originally reported to have an angiogenic function, have been detected not only in the vascular system and adipose tissue but also in rheumatoid joints. | |||
TMPY-03065 |
BACE2 Protein, Mouse, Recombinant (His)
CEAP1,BAE2,1110059C24Rik,β-site APP-cleaving enzyme 2,CDA13,... |
Mouse | HEK293 Cells |
BACE2, also known as beta secretase 2, belongs to the peptidase A1 family. It is a protease known to be an important enzyme involved in the cellular pathways. BACE2 has been shown to interact with GGA1 and GGA2. It is the major β-secretase in vivo. BACE2 is located on chromosome 21 and may play a role in alzheimer's disease pathogenesis in down syndrome(DS). Overexpression of BACE2 by lentivirus markedly reduced amyloid β protein production in primary neurons. Despite an extra copy of the BACE2 ... | |||
TMPY-01188 |
PARP Protein, Human, Recombinant (His)
ADPRT1,ADPRT,pADPRT-1,PPOL,ARTD1,PARP-1,poly (ADP-r... |
Human | Baculovirus Insect Cells |
PARP Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 114.5 kDa and the accession number is A0A024R3T8. | |||
TMPY-06723 |
Cyp c 1 Protein, Common carp, Recombinant
|
Common carp | E. coli |
Cyp c 1 Protein, Common carp, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12.5 kDa. | |||
TMPH-01943 |
PARP4 Protein, Human, Recombinant (His)
|
Human | E. coli |
PARP4 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-00349 |
Car b 1 isoforms 1A and 1B Protein, Carpinus betulus, Recombinant (His)
Allergen Car b I,Major pollen allergen Car b 1 isoforms 1A a... |
Carpinus betulus | E. coli |
Car b 1 isoforms 1A and 1B Protein, Carpinus betulus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.3 kDa and the accession number is P38949. | |||
TMPH-01945 |
TIPARP Protein, Human, Recombinant (His)
|
Human | Baculovirus Insect Cells |
TIPARP Protein, Human, Recombinant (His) is expressed in Baculovirus. | |||
TMPH-00348 |
Car b 1 isoform 2 Protein, Carpinus betulus, Recombinant (His)
Major pollen allergen Car b 1 isoform 2,Car b 1,Allergen Car... |
Carpinus betulus | E. coli |
Car b 1 isoform 2 Protein, Carpinus betulus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.4 kDa and the accession number is P38950. | |||
TMPH-01880 |
PARP2 Protein, Human, Recombinant (His)
|
Human | E. coli |
PARP2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 72.2 kDa and the accession number is Q9UGN5. | |||
TMPH-01882 |
PARP9 Protein, Human, Recombinant (His)
|
Human | E. coli |
PARP9 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.0 kDa and the accession number is Q8IXQ6. | |||
TMPH-03372 |
Sharpin Protein, Rat, Recombinant (His & Myc)
|
Rat | E. coli |
Sharpin Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 47.7 kDa and the accession number is Q9EQL9. | |||
TMPH-01879 |
PARP11 Protein, Human, Recombinant (His)
|
Human | E. coli |
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Plays a role in nuclear envelope stability and nuclear remodeling during spermiogenesis. PARP11 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 41.0 kDa and the accession number is Q9NR21. | |||
TMPH-01944 |
PARP9 Protein, Human, Recombinant (His & Myc)
|
Human | HEK293 Cells |
PARP9 Protein, Human, Recombinant (His & Myc) is expressed in HEK293. | |||
TMPH-01881 |
PARP2 Protein, Human, Recombinant (GST & His)
|
Human | Baculovirus Insect Cells |
PARP2 Protein, Human, Recombinant (GST & His) is expressed in Baculovirus insect cells with N-GST and C-6xHis tag. The predicted molecular weight is 92.8 kDa and the accession number is Q9UGN5. | |||
TMPH-01942 |
PARP14 Protein, Human, Recombinant (His & Myc)
|
Human | HEK293 Cells |
PARP14 Protein, Human, Recombinant (His & Myc) is expressed in HEK293. | |||
TMPY-02465 |
PARP Protein, Mouse, Recombinant (His)
AI893648,Adprp,5830444G22Rik,C80510,sPARP-1,poly (A... |
Mouse | Baculovirus Insect Cells |
PARP Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 115 kDa and the accession number is Q921K2. | |||
TMPY-06355 |
Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His)
转化生长因子,TGF β1 & GARP Heterotrimer |
Human | HEK293 Cells |
Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 108.72 kDa and the accession number is P01137. | |||
TMPH-01941 |
PARP12 Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
PARP12 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPY-02421 |
PARP3 Protein, Human, Recombinant (His & GST)
ARTD3,IRT1,ADPRTL2,ADPRTL3,poly (ADP-ribose) polymerase fami... |
Human | Baculovirus Insect Cells |
Poly(ADP-ribose) polymerase 3 (PARP3) is an important member of the PARP family and shares high structural similarities with both PARP1 and PARP2. Poly(ADP-ribose) polymerase 3 (PARP3), a critical player in cellular response to DNA double-strand breaks (DSBs), plays an essential role in the maintenance of genome integrity. The ADP ribosyl transferase [poly(ADP-ribose) polymerase] ARTD3(PARP3) is a newly characterized member of the ARTD(PARP) family that catalyzes the reaction of ADP ribosylation... |