95
72
1
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Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0097 |
Mag Beads Epoxy
环氧磁珠 (300 nm) |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6075 |
Epothilone B
帕妥匹隆,Patupilone,EPO 906 |
Apoptosis; Microtubule Associated; Antibiotic; Antifungal | Apoptosis; Cytoskeletal Signaling; Microbiology/Virology |
Epothilone B (EPO 906) 是微管稳定剂,Ki 为0.71 μM。 它与αβ-微管蛋白异二聚体亚基结合,使αβ-微管蛋白解离减少。 | |||
T82456 |
EPO mimetic peptide-1
EMP-1 |
||
EPO mimetic peptide-1 (EMP-1)为含20个氨基酸的多肽,该化合物具有促进细胞增殖、影响细胞周期以及诱导网织细胞产生的作用。 | |||
T69480 | Sagopilone | ||
Sagopilone is a fully synthetic low-molecular-weight epothilone with potential antineoplastic activity. Sagopilone binds to tubulin and induces microtubule polymerization while stabilizing microtubules against depolymerization, which may result in the inhibition of cell division, the induction of G2/M arrest, and apoptosis. The agent is not a substrate for the P-glycoprotein (P-gp) efflux pump and so may exhibit activity in multidrug-resistant (MDR) tumors. The epothilone class of metabolites wa... | |||
T37149 |
Carbamazepine 10,11-epoxide
|
Others | Others |
Carbamazepine 10,11-epoxide 是抗惊厥药卡马西平 (carbamazepine) 的活性代谢物。它由卡马西平通过微粒体中的细胞色素 P450 (CYP) 同种型 CYP3A4 和 CYP2C8 形成,微粒体分别由表达 CYP3A4 或 CYP2C8 的 HepG2 细胞制备。它对小鼠电击诱发的癫痫发作具有抗惊厥活性。 | |||
T12427 |
Brepocitinib P-Tosylate
PF-06700841 P-Tosylate |
JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Brepocitinib P-Tosylate (PF-06700841 P-Tosylate) 是一种有效的 JAK1和TYK2双重抑制剂,IC50值分别为 17 和 23 nM。它还抑制JAK2和JAK3,IC50值分别为 77 和 6.49 μM。 | |||
T9601 |
Tepotinib hydrochloride(1 : x)
|
c-Met/HGFR; P-gp; ABC | Membrane transporter/Ion channel; Neuroscience; Tyrosine Kinase/Adaptors |
Tepotinib hydrochloride(1 : x) 是一种口服生物可利用的间充质-上皮转化 (MET) TKI,主要针对具有 METex14 跳跃突变的特定 NSCLC 患者开发。 | |||
T6405 |
Bepotastine Besilate
Talion,TAU 284,苯磺酸贝托司汀,Bepreve,Bepotastine Beslilate |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Bepotastine Besilate (TAU 284) 是一种选择性可口服的组胺 H1 受体拮抗剂,可用于过敏性鼻炎、过敏性结膜炎、荨麻疹和瘙痒症的研究。 | |||
T9962 |
Mepolizumab
美泊利单抗,SB 240563 |
IL Receptor | Immunology/Inflammation |
Mepolizumab (SB 240563) 是一种中和 IL-5 的人源化单克隆抗体。 美泊利单抗可用于严重嗜酸性哮喘和嗜酸性肉芽肿伴多血管炎的研究。 | |||
TQ0010 |
Brepocitinib
PF-06700841 |
Tyrosine Kinases; JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors |
Brepocitinib (PF-06700841) 是JAK1和TYK2双重抑制剂,IC50分别为 17 nM 和 23 nM。它抑制JAK2和JAK3的效果较弱,IC50分别为 77 nM 和 6.49 μM 。 | |||
T4071 |
Repotrectinib
TPX-0005,TPX 0005,TPX0005 |
Trk receptor; ROS; Src; ALK; ROS Kinase | Angiogenesis; Immunology/Inflammation; Tyrosine Kinase/Adaptors |
Repotrectinib (TPX-0005) 是ROS1(IC50=0.07 nM) 和TRK(对 TRKA/B/C 的IC50=0.83/0.05/0.1 nM) 抑制剂,能够抑制 WTALK(IC50=1.01 nM)。它具有抗癌作用。 | |||
T68664 |
Epostane
Win-32729 |
Dehydrogenase | Metabolism |
Epostane (Win-32729) 是一种 3β- 羟基类固醇脱氢酶抑制剂,通过抑制 3β-羟类固醇脱氢酶发挥作用,阻断黄体酮的产生。 | |||
T3112 |
Verteporfin
维替泊芬,BPD-MA,CL 318952 |
Apoptosis; YAP; VDA; Autophagy | Angiogenesis; Apoptosis; Autophagy; Stem Cells |
Verteporfin (BPD-MA) 是一种 YAP 抑制,抑制 YAP-TEAD 相互作用。Verteporfin 也是一种光敏剂,用于光动力疗法。Verteporfin 还可以诱导细胞凋亡,抑制自噬。 | |||
T32105 |
Cipepofol
HSK3486,HSK 3486,HSK-3486 |
||
HSK3486 is similar to propofol and is a general anesthetic, which may have therapeutic potential in insomnia, migraine, anxiety, analgesia, and other aspects. | |||
T1171L |
Methylprednisolone Aceponate
MPA,SH 440,SH-440,SH440,Advantan,醋丙甲泼尼龙 |
Others | Others |
Methylprednisolone Aceponate (SH 440) 是一种非卤化皮质类固醇,是一种有效的抗炎剂。 | |||
T3444 |
Merimepodib
美泊地布,VX-497,VI-21497 |
Dehydrogenase; Antiviral; HCV Protease; HBV | Immunology/Inflammation; Metabolism; Microbiology/Virology; Proteases/Proteasome |
Merimepodib (VX-497) 是一种新型非竞争性肌苷一磷酸脱氢酶抑制剂,具有广谱抗病毒活性。 | |||
T34383 |
Rofleponide
|
Glucocorticoid Receptor | Endocrinology/Hormones |
Rofleponide 是一种人工合成的糖皮质激素,与大鼠胸腺糖皮质激素受体有很高的亲和力。 | |||
T39520 |
Vamifeport
VIT-2763 |
Ferroptosis | Apoptosis |
Vamifeport (VIT-2763) 是一种新型具有口服活性且靶向铁转运蛋白的抑制剂,可降低 SCD Townes 模型中的溶血标志物。VIT-2763 可改善贫血和红细胞生成,可改善血管炎症,可研究 β-地中海贫血。 | |||
T6121 |
Tepotinib
特泊替尼,EMD-1214063,MSC2156119 |
Trk receptor; c-Met/HGFR; TAM Receptor | Tyrosine Kinase/Adaptors |
Tepotinib (EMD-1214063) 是一种具有潜在抗肿瘤活性的 MET 酪氨酸激酶抑制剂。 | |||
T19721 |
Epoxiconazole
BAS-480F,BAS 480F,EC 406 850 2,氟环唑,BAS480F,EC-406-850-2 |
Antifungal | Microbiology/Virology |
Epoxiconazole (BAS-480F) 是一种 14-α 去甲基化酶抑制剂,抑制麦角甾醇的合成和真菌细胞壁的形成。它是一种杀菌剂,对耐多菌灵和耐苯甲酰胺的菌株均表现出强大的抑制作用,可用于控制多种农作物病害。 | |||
T22307 |
Diclofenac Epolamine
diclofenac hydroxyethylpyrrolidine,DHEP,2-((2,6-二氯苯基)氨基)苯乙酸 1-吡咯烷乙醇盐,DIEP |
Others | Others |
Diclofenac Epolamine (DHEP) 是一种非甾体抗炎药 (NSAID),具有镇痛和解热作用。 | |||
T35973 |
Cholesterol-5α,6α-epoxide
Epoxycholesterol,5α,6α-epoxy Cholestanol,NSC 18176 |
Others | Others |
Cholesterol-5α,6α-epoxide (Epoxycholesterol) 是胆固醇氧化产生的代谢产物。 在应用他莫昔芬和 PBPE 后,5α,6α-环氧胆甾烷醇通过与 LXRβ 结合诱导三酰甘油生物合成。 | |||
T5333 |
Rimeporide hydrochloride
盐酸Rimeporide,EMD-87580 hydrochloride |
Sodium Channel | Membrane transporter/Ion channel |
Rimeporide hydrochloride (EMD-87580 hydrochloride) 是一种有效的 Na+/H+交换泵(NHE-1) 选择性抑制剂。 | |||
T3223 |
16beta-Methyl-16alpha,17alpha-epoxypregnenolone
|
Others | Others |
16beta-Methyl-16alpha,17alpha-epoxypregnenolone 用作药物中间体。 | |||
T19277 |
Dexamethasone 9,11-epoxide
|
Others | Others |
Dexamethasone 9,11-epoxide 是一种萃取得到的化合物,是制备地塞米松的中间体。 | |||
T7893 |
Bepotastine
Bepotastine free base,贝托斯汀 |
Others; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience; Others |
Bepotastine (Bepotastine free base) 是一种选择性可口服的组胺 H1 受体拮抗剂,可用于过敏性鼻炎、过敏性结膜炎、荨麻疹和瘙痒症的研究。 | |||
T32114 |
Hydrocortisone aceponate
Suniderma,Efficort,Hydrocortisone 17-propionate 21-acetate |
Glucocorticoid Receptor | Endocrinology/Hormones |
Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) 是一种有效的外用糖皮质激素,以乳膏的形式用于治疗各种皮肤病。 | |||
T62356 |
Mardepodect hydrochloride
PF-2545920 HCl,Mardepodect HCl,MP-10 HCl,PF-02545920 HCl |
Apoptosis; PDE | Apoptosis; Metabolism |
Mardepodect hydrochloride (Mardepodect HCl) 是一种可穿过血脑屏障且具有口服活性的、选择性和高效性的 PDE10A 抑制剂(IC50 :0.37 nM)。Mardepodect hydrochloride 可上调编码特定生长因子、转录因子、细胞信号分子和细胞表面蛋白的基因,同时下调广泛的可靶向细胞周期和细胞凋亡相关基因。 | |||
TQ0300 |
Conduritol B epoxide
|
Glucosidase | Metabolism |
Conduritol B epoxide 是不可逆的,β-glucosidase 共价抑制剂。 | |||
T5319 |
Rimeporide
EMD-87580 |
Sodium Channel | Membrane transporter/Ion channel |
Rimeporide (EMD-87580) 是有效的 Na+/H+交换泵 (NHE-1) 选择性抑制剂。 | |||
T3219 |
16,17-Epoxypregnenolone acetate
16alpha,17alpha-Epoxypregnenolone acetate,16,17-环氧孕烯醇酮醋酸酯 |
Others | Others |
16,17-Epoxypregnenolone acetate (16alpha,17alpha-Epoxypregnenolone acetate) 可由洋葱伯克霍尔德菌 SE-1 生产。 | |||
T7724 |
Tepoxalin
RWJ-20485,RWJ20485,ORF20485,替泊沙林,ORF-20485,RWJ 20485,ORF 20485 |
Lipoxygenase; COX | Immunology/Inflammation; Metabolism; Neuroscience |
Tepoxalin (RWJ 20485) 是有效的5-脂氧合酶和环氧合酶抑制剂,表现出强大的抗炎活性和较小的胃肠道刺激性。 | |||
T3225 |
16,17-Epoxy-21-acetoxypregnenolone
|
Others | Others |
16,17-Epoxy-21-acetoxypregnenolone 用作药物中间体。 | |||
T3222 |
16,17-Epoxypregnenol
16alpha,17alpha-Epoxypregnenolone,16,17-环氧孕烯醇酮 |
Others | Others |
16,17-Epoxypregnenol 用作药物中间体。 | |||
T16499 |
Mardepodect
PF-2545920 |
PDE | Metabolism |
Mardepodect (PF-2545920) 是一种有效的、口服具有活性的、可透过血脑屏障的、选择性的 PDE10A 抑制剂,IC50=0.37 nM,比作用于其他 PDE 选择性高 1000 多倍。 | |||
T19532 |
Fobrepodacin disodium
pVXc-486 disodium,SPR720 disodium |
Others | Others |
SPR720 disodium is an orally active and potent phosphate VXc-486 prodrug,has potent bactericidal activities in vivo. | |||
T26061 |
Reposal
WT-161,Reposamal,Reposal novo,WT161,WT 161 |
||
Reposal is a barbiturate derivative invented in the 1960s in Denmark. It has hypnotic, sedative, and anticonvulsant properties, and was used primarily for the therapy of insomnia. | |||
T76314 |
Epobis
|
||
Epobis,一种重组树突状肽,有效地激动erythropoietin receptor,具有促进初级运动神经元神经纤维生成、减少TNF释放以及穿透血脑屏障的功能。Epobis展现出显著的抗炎和增强记忆力特性。 | |||
T71756 |
24(S),25-Epoxycholesterol
|
||
24(S),25-Epoxycholesterol is an oxysterol agonist of the liver X receptor. | |||
T66307 |
(2S,3S)-N-t-Boc-3-amino-1,2-epoxy-4-phenylbutane
|
||
(2S,3S)-N-t-Boc-3-amino-1,2-epoxy-4-phenylbutane 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66307,CAS号为 98737-29-2。 | |||
T64173 |
Epocholeone
|
||
Epocholeone 是一种生长调节剂,能够用于作物的真菌或生理性病害的防治。 | |||
T71921 |
cis-Epoxysuccinic acid
|
||
cis-Epoxysuccinic acid 是succinate receptor(SUCNR1/GPR91)的激动剂,能够降低cAMP水平,其EC50值为2.7 µM。它适用于心血管系统的研究。 | |||
T68232 |
Epofolate
|
||
Epofolate is folate receptor-targeting antimitotic agent with potential antineoplastic activity. Folate receptor-targeted epothilone BMS753493 contains an epothilone moiety linked to a single folate molecule. Mediated through the folate moiety, this agent delivers the antimitotic epothilone component into cells expressing folic acid receptors, frequently upregulated in many types of tumor cells. After ligand-receptor internalization, the epothilone moiety induces microtubule polymerization and s... | |||
T25382 |
Epostatin
|
||
Epostatin is a new dipeptidyl peptidase II (DPP-II, EC 3.4.14.2) inhibitor. | |||
T63965 |
Bepotastine tosylate
|
||
Bepotastine tosylate 是一种选择性、口服具有活力的第二代组胺 H1 受体 (histamine H1 receptor) 拮抗剂,对组胺介导的神经生长因子 (NGF) 表达上调表现出抑制作用。Bepotastine tosylate 能够用于研究过敏性鼻炎,过敏性结膜炎和荨麻疹/瘙痒症。 | |||
T70284 |
Epolactaene
|
||
Epolactaene is a neuritogenic compound in human neuroblastoma cells which selectively inhibit the activities of mammalian DNA polymerases and human DNA topoisomerase II. | |||
T83451 |
14,15-Epoxyeicosatrienoic acid
14,15-EET |
||
14,15-Epoxyeicosatrienoic acid(14,15-EET)是花生四烯酸的代谢物,具有显著的体内抑制血小板聚集的作用。此外,它能促进星形胶质细胞清除Aβ,因而在老年痴呆症的研究中具有潜在应用价值。 | |||
T126129 |
4,7'-Epoxy-4',9'-dihydroxy-3',5,5'-trimethoxy-3,8'
|
||
4,7'-Epoxy-4',9'-dihydroxy-3',5,5'-trimethoxy-3,8' 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126129,CAS号为 1264177-64-1。 | |||
T82454 |
Epoetin zeta
|
||
Epoetin zeta,内源性促红细胞生成素(Erythropoietin)的衍生物,作为促红细胞生成剂使用。它主要应用于肾源性贫血及其相关研究领域。 | |||
TMIH-0360 |
N(4)-desoxychlordiazepoxide-d5
|
||
N(4)-desoxychlordiazepoxide-d5 是 N(4)-desoxychlordiazepoxide 的氘代化合物。N(4)-desoxychlordiazepoxide 的 CAS 号为 4393-72-0。 | |||
T31318 | Decane, 1,2:9,10-diepoxy- | ||
Decane, 1,2:9,10-diepoxy- is a biochemical. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6490 |
Epothilone A
埃博霉素 A,epothile,Epo A |
Apoptosis; Microtubule Associated | Apoptosis; Cytoskeletal Signaling |
Epothilone A (Epo A) 是紫杉醇和管蛋白聚合物结合的一种竞争性抑制剂,其Ki 值为 0.6-1.4 μM。 | |||
T4S1999 |
Valepotriate
戊曲酯/缬草素,Valtrate |
Apoptosis; HIV Protease | Apoptosis; Microbiology/Virology; Proteases/Proteasome |
Valepotriate (Valtrate) 是从蜘蛛香分离而来的一种天然产物,是一类新的细胞毒剂和抗肿瘤剂,对 HTC 肝癌细胞是非常有效的细胞毒剂。 它可能对焦虑的精神症状具有潜在的抗焦虑作用。 | |||
T6830 |
Epoxomicin
BU-4061T,BU-4061T,Aids010837,环氧酶素 |
Apoptosis; Proteasome | Apoptosis; Proteases/Proteasome; Ubiquitination |
Epoxomicin (BU-4061T,Aids010837) 是一种含环氧酮的天然产物,可穿越血脑屏障,并具有很强的抗肿瘤和抗炎活性。它是一种选择性不可逆的蛋白酶体抑制剂,抑制类胰凝乳蛋白酶的活性。 | |||
TQ0234 |
Epoxymicheliolide
1β,10β-Epoxymicheliolide,环氧木香内酯 |
Others | Others |
Epoxymicheliolide (1β,10β-Epoxymicheliolide) 是木香内酯衍生物的一种。 | |||
TN6730 |
Epoxyazadiradione
|
NF-κB | NF-κB |
Epoxyazadiradione 是从印楝果实中得到的柠檬苦素。它能够可逆的、非竞争性的抑制人类、约氏疟原虫、疟原虫的互变异构酶活性。它具有抗疟原虫和人类 MIF 诱导的促炎反应的潜力。 | |||
T8014 |
Epoxylinalool
氧化芳樟醇,2-(2-Hydroxy-2-Propyl)-5-Methyl-5-Vinyltetrahydrofuran |
Others | Others |
Epoxylinalool (2-(2-Hydroxy-2-Propyl)-5-Methyl-5-Vinyltetrahydrofuran) 是一种天然存在的单萜醇,广泛用于香水和调味品的生产。 | |||
TN1159 |
(1(10)E,2R*,4R*)-2-Methoxy-8,12-epoxygermacra-1(10),7,11-trien-6-one
[(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one |
Others | Others |
(1(10)E,2R*,4R*)-2-Methoxy-8,12-epoxygermacra-1(10),7,11-trien-6-one ([(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one) 是一种来自姜黄的倍半萜。 | |||
TN7127 |
5,6-Epoxyergosterol
|
Others | Others |
5,6-Epoxyergosterol 来源于内生真菌 Phyllosticta capitalensis。 | |||
TN1100 |
Nepodin
|
transporter; COX; AMPK; Parasite | Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling |
Nepodin 是从Rumex crispus 中分离的一种醌氧化还原酶抑制剂,具有抗糖尿病和抗疟疾的作用。。它通过激活 AMPK 刺激 GLUT4 向质膜的转运。 | |||
T7931 |
16a,17a-Epoxy-4-Pregnen-3,20-Dione
|
Others | Others |
16a,17a-Epoxy-4-Pregnen-3,20-Dione 是一种合成孕激素,是黄体酮激素的代谢产物,它通过与黄体酮受体结合发挥作用,已被用于研究孕激素对生殖器官的影响,激素对细胞生长和发育的影响,以及激素对免疫系统的影响。 | |||
T13616 |
cis-9,10-Epoxystearic acid
cis-9,10-Epoxystearic acid,cis-9,10-Epoxyoctadecanoic acid |
Endogenous Metabolite | Metabolism |
cis-9,10-Epoxystearic acid (cis-9,10-Epoxyoctadecanoic acid) 是来自人血液和尿液的内源性成分。它可以通过油酸和非酶环氧化反应从油酸中制备。 | |||
TN2667 |
1beta,10beta-Epoxydehydroleucodin
|
Others | Others |
1beta,10beta-Epoxydehydroleucodin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2667,CAS号为 130858-00-3。 | |||
TN5420 |
3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan
|
||
3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5420,CAS号为 873867-94-8。 | |||
TN6320 |
(19S,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol
|
||
(19S,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6320,CAS号为 1616120-83-2。 | |||
TN6333 |
(19R,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol
|
||
(19R,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6333,CAS号为 2281872-79-3。 | |||
TN6332 |
(19S,23R)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol
|
||
(19S,23R)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6332,CAS号为 1474062-47-9。 | |||
TN3384 |
alpha-Epoxydihydroartemisinic acid
|
Others | Others |
alpha-Epoxydihydroartemisinic acid 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3384,CAS号为 380487-65-0。 | |||
T83260 |
6β,7β-Epoxyasteriscunolide A
|
||
6β,7β-Epoxyasteriscunolide A 是一种具有细胞毒性的倍半萜类化合物,其对 HL-60 和 MOLT-3 白血病细胞系展现出的 IC50 值介于 4.1-5.4 μM 之间。 | |||
T83578 |
(19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol
|
||
(19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol 是一种葫芦烷型三萜。该化合物在 MTT 法检测中对癌细胞系 MCF-7、HepG2、Du145、Colon205 以及 HL-60 均未表现出抑制效果。 | |||
TN3980 | Epoxyparvinolide | Others | Others |
Epoxyparvinolide是一种天然产物,属于唇形科刺蕊草属,其产品编号为 TN3980,CAS号为 102227-61-2。Epoxyparvinolide可用作对照参考。 | |||
TN5584 | ent-11α,16α-Epoxy-15α-hydroxykauran-19-oic acid | ||
ent-11α,16α-Epoxy-15α-hydroxykauran-19-oic acid 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5584,CAS号为 77658-46-9。 | |||
TN2633 | 15,16-Epoxy-15-ethoxy-6beta,13-dihydroxylabd-8-en-7-one | Others | Others |
15,16-Epoxy-15-ethoxy-6beta,13-dihydroxylabd-8-en-7-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2633,CAS号为 1374328-47-8。 | |||
TN5375 |
1β,10β-Epoxy-6β-isobutyryloxy-9-oxofuranoeremophilane
|
||
1beta,10beta-Epoxy-6beta-isobutyryloxy-9-oxofuranoeremophilane is a natural product from Ligularia fischeri. | |||
TN2819 |
24,25-Epoxytirucall-7-en-3,23-dione
|
Others | Others |
24,25-Epoxytirucall-7-en-3,23-dione 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2819,CAS号为 890928-81-1。 | |||
TN5370 |
1β,10β-Epoxydesacetoxymatricarin
|
||
1beta,10beta-Epoxydesacetoxymatricarin shows high anti-hypercholesterolemic potential. | |||
TN2716 |
2',4'-Dihydroxy-3,7':4,8'-diepoxylign-7-ene
|
Others | Others |
2',4'-Dihydroxy-3,7':4,8'-diepoxylign-7-ene 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2716,CAS号为 666250-52-8。 | |||
TN3074 |
5,19-Epoxy-25-methoxycucurbita-6,23-dien-3-ol
|
Others | Others |
5,19-Epoxy-25-methoxycucurbita-6,23-dien-3-ol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3074,CAS号为 81910-39-6。 | |||
T81952 |
Lanosta-7,9(11),23,25(27)-tetraen-26-oic acid, 23,27-epoxy-3-oxo-
|
||
Lanosta-7,9(11),23,25(27)-tetraen-26-oic acid, 23,27-epoxy-3-oxo- 是一种从土津皮 (山楝的根皮) 提取的羊毛甾烷型化合物。 | |||
TN5329 |
Epitulipinolide diepoxide
|
||
Epitulipinolide diepoxide has antioxidative and chemopreventive activities in skin melanoma cells, can significantly inhibit the proliferation of melanoma cells, it possesses cytotoxic activity against KB cells. | |||
TN2589 |
11alpha,12alpha-Epoxy-3beta,23-dihydroxy-30-norolean-20(29)-en-28,13beta-olide
|
Others | Others |
11alpha,12alpha-Epoxy-3beta,23-dihydroxy-30-norolean-20(29)-en-28,13beta-olide is a natural product from Paeonia lactiflora. | |||
T82453 |
Epothilone D1
|
||
Epothilone D1为分离得到的天然产物,展现对小鼠成纤维细胞的细胞毒性。 | |||
T31658 |
Epoxyparthenolide
|
||
Epoxyparthenolide is a biochemical. | |||
T83570 |
(23E)-5b,19-epoxycucurbita-6,23,25(26)-triene-3b-ol
|
||
(23E)-5b,19-epoxycucurbita-6,23,25(26)-triene-3b-ol,一种葫芦烷三萜,可从苦瓜籽中提取。 | |||
TN6492 | (1E)-3-methoxy-8,12-epoxygermacra-1,7,10,11-tetraen-6-one | ||
(1E)-3-methoxy-8,12-epoxygermacra-1,7,10,11-tetraen-6-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6492,CAS号为 1393342-06-7。 | |||
TN3007 | 4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan | Others | Others |
4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan shows cytotoxic activities against four tumor cell lines (A549, SK-OV-3, SKMEL-2 and HCT15). | |||
T10197 |
8,9-Epoxy-3-isobutyryloxy-10-(2-methylbutanoyl)thymol
8,9-环氧-3-异丁酰-10-(2-甲基丁酰) 百里草酚,8-9-epoxy-3-isobutyryloxy-10-2-methylbutanoyl-thymol |
Others | Others |
8,9-Epoxy-3-isobutyryloxy-10-(2-methylbutanoyl)thymol is a chemical composition of essential oils from Telekia speciosa. It also shows marked antipro-liferative activity against human cancer cell lines in vitro. | |||
TN2508 | 1,6-Dihydro-4,7'-epoxy-1-methoxy-3',4'-methylenedioxy-6-oxo-3,8'-lignan | Others | Others |
1,6-Dihydro-4,7'-epoxy-1-methoxy-3',4'-methylenedioxy-6-oxo-3,8'-lignan 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2508,CAS号为 67920-48-3。 | |||
T37810 |
6',7'-Epoxybergamottin
|
||
6'7'-Epoxybergamottin is a furanocoumarin found in grapefruit. It is a potent inhibitor of the cytochrome P450 (CYP) isoform CYP3A4 with an IC50 value of 0.30 ppm in a cell-free assay, 0.33 μM in HL7 human liver cells, and 0.22 μM in S9 human intestine cells. It has been studied in the context of drug interactions with grapefruit constituents. It is found in grapefruit juice at concentrations of 0.1-7.4 μM and inhibits the transport of talinolol , a permeability glycoprotein (P-gp/ABCB1) transpo... | |||
TN2818 |
24,25-Epoxydammar-20(21)-en-3-one
|
Others | Others |
24,25-Epoxydammar-20(21)-en-3-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2818,CAS号为 63543-52-2。 | |||
TN3202 |
6beta-Angeloyloxy-1beta,10beta-epoxy-9-oxofuranoeremophilane
|
Others | Others |
6beta-Angeloyloxy-1beta,10beta-epoxy-9-oxofuranoeremophilane is a natural product from Ligularia songarica. | |||
TN6345 |
(19S,23E)-5β,19-Epoxy-19-methoxycucurbita-6,23,25-trien-3β-ol
|
||
(19S,23E)-5β,19-Epoxy-19-methoxycucurbita-6,23,25-trien-3β-ol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6345,CAS号为 874287-87-3。 | |||
TN5949 |
5β,19-Epoxy-19,25-dimethoxycucurbita-6,23-dien-3β-ol
|
||
5β,19-Epoxy-19,25-dimethoxycucurbita-6,23-dien-3β-ol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5949,CAS号为 85372-70-9。 | |||
TN4958 |
Schisandrin C epoxide
|
Others | Others |
Schisandrin C epoxide 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4958,CAS号为 81345-36-0。 | |||
TN6329 |
16α-Hydroxy-19,20-epoxy-20β-methoxy-ent-kaurane
|
||
16α-Hydroxy-19,20-epoxy-20β-methoxy-ent-kaurane 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6329,CAS号为 197369-57-6。 | |||
TN3313 |
9-Deacetyl-9-benzoyl-10-debenzoyl-4beta,20-epoxytaxchinin A
|
Others | Others |
9-Deacetyl-9-benzoyl-10-debenzoyl-4beta,20-epoxytaxchinin A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3313,CAS号为 227011-48-5。 | |||
TN2795 |
20,24-Epoxy-24-methoxy-23(24-25)abeo-dammaran-3-one
|
Others | Others |
20,24-Epoxy-24-methoxy-23(24-25)abeo-dammaran-3-one 用作参考标准化合物,可用于生命科学领域相关研究。 | |||
TN2631 |
15,16-Epoxy-12R-hydroxylabda-8(17),13(16),14-triene
|
Others | Others |
15,16-Epoxy-12R-hydroxylabda-8(17),13(16),14-triene 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2631,CAS号为 61597-55-5。 | |||
T35483 |
19,20-Epoxycytochalasin D
|
||
19,20-Epoxycytochalasin D is a fungal metabolite that has been found in the endophytic fungus Nemania sp. UM10M. It is active against the chloroquine-sensitive and -resistant strains of P. falciparum (MIC = 0.4 ng/ml for both) without inducing cytotoxicity in Vero cells. It is cytotoxic to BT-549, LLC-PK11, and P388 cells (IC50s = 7.84, 8.4, and 0.16 µM, respectively) but not SK-MEL, KB, or SKOV3 cells up to a concentration of 10 µM. | |||
TN4229 |
Humulene epoxide II
|
Antifection | Microbiology/Virology |
Humulene epoxide II has antimalarial activity. | |||
TN5758 | 1,5-Epoxy-3-hydroxy-1-(3,4-dihydroxy-5-methoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane | ||
1,5-Epoxy-3-hydroxy-1-(3,4-dihydroxy-5-methoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5758,CAS号为 182369-54-6。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00071 |
EPO/Erythropoietin Protein, Human, Recombinant (His)
Erythropoietin,EPO,红细胞生长素,Epoetin |
Human | HEK293 Cells |
Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoietin is a member of the EPO/TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. The differentiation of CFU-E (Colony Forming Unit-Erythroid) cells into erythrocytes can only be accomplished in the presence of EPO. Physiological levels of EP... | |||
TMPY-01883 |
EPOR Protein, Human, Recombinant (His)
erythropoietin receptor,EPO-R |
Human | HEK293 Cells |
EPOR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P19235-1. | |||
TMPK-00077 |
EPO/Erythropoietin Protein, Human, Recombinant
EPO,MVCD2,红细胞生长素,Epoetin,Erythropoietin,EP |
Human | HEK293 Cells |
Erythropoietin (EPO) is a circulating hormone conventionally considered to be responsible for erythropoiesis. In addition to facilitating red blood cell production, EPO has pluripotent potential, such as for cognition improvement, neurogenesis, and anti-fibrotic, anti-apoptotic, anti-oxidative, and anti-inflammatory effects. | |||
TMPY-00443 |
EPO/Erythropoietin Protein, Mouse, Recombinant
红细胞生长素,erythropoietin |
Mouse | HEK293 Cells |
EPO/Erythropoietin Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.6 kDa and the accession number is P07321. | |||
TMPY-00639 |
EPO/Erythropoietin Protein, Human, Recombinant (hFc)
红细胞生长素,MVCD2,Erythropoietin,EP |
Human | HEK293 Cells |
EPO/Erythropoietin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.1 kDa and the accession number is G9JKG7. | |||
TMPY-01107 |
TIMP-1 Protein, Human, Recombinant
EPO,TIMP metallopeptidase inhibitor 1,TIMP-1,HCI,CL... |
Human | HEK293 Cells |
TIMP-1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21 kDa and the accession number is P01033. | |||
TMPY-02049 |
EPOR & CD131 Heterodimer Protein, Human, Recombinant (hFc)
EPO-R,erythropoietin receptor |
Human | HEK293 Cells |
EPOR & CD131 Heterodimer Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101 kDa and the accession number is NP_000112.1&NP_000386.1. | |||
TMPY-00794 |
EPOR Protein, Human, Recombinant (hFc)
EPO-R,erythropoietin receptor |
Human | HEK293 Cells |
EPOR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.0 kDa and the accession number is P19235-1. | |||
TMPY-06109 |
EPOR Protein, Human, Recombinant (His), Biotinylated
EPO-R,erythropoietin receptor |
Human | HEK293 Cells |
EPOR Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P19235-1. | |||
TMPY-00154 |
TIMP-1 Protein, Human, Recombinant (hFc)
TIMP-1,TIMP metallopeptidase inhibitor 1,EPA,EPO,CL... |
Human | HEK293 Cells |
TIMP-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is P01033. | |||
TMPY-00932 |
TIMP-1 Protein, Human, Recombinant (His)
CLGI,EPA,TIMP,TIMP-1,EPO,TIMP metallopeptidase inhi... |
Human | HEK293 Cells |
TIMP-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is P01033. | |||
TMPY-02986 |
EPO/Erythropoietin Protein, Mouse, Recombinant (His)
红细胞生长素,erythropoietin |
Mouse | HEK293 Cells |
EPO/Erythropoietin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is P07321. | |||
TMPY-00462 |
EPO/Erythropoietin Protein, Cynomolgus, Recombinant (His)
红细胞生长素,erythropoietin |
Cynomolgus | HEK293 Cells |
EPO/Erythropoietin Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.7 kDa and the accession number is XP_005549312.1. | |||
TMPY-02073 |
EPO/Erythropoietin Protein, Rat, Recombinant (His)
红细胞生长素,erythropoietin |
Rat | Baculovirus Insect Cells |
EPO/Erythropoietin Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 20 kDa and the accession number is P29676-1. | |||
TMPK-00093 |
TIMP-1 Protein, Mouse, Recombinant (hFc)
TPA-S1,CLGI,TIMP-1,EPO,TIMP,EPA,EPATIMP-1,TPAS1 |
Mouse | HEK293 Cells |
Tissue inhibitor of metalloprotease-1 (TIMP-1) is a tissue inhibitor of matrix metalloproteinases (MMPs). It however exerts multiple effects on biological processes, such as cell growth, proliferation, differentiation and apoptosis, in an MMP-independent manner. | |||
TMPH-03287 |
EPOR Protein, Rat, Recombinant (His & SUMO)
|
Rat | E. coli |
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate LYN tyrosine kinase. EPOR Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO and C-6xHis tag. The predicted molecular weight is 39.1 kDa and the accession number is Q07303. | |||
TMPH-03643 |
TmpB Protein, Treponema phagedenis, Recombinant (His & Myc)
|
Treponema phagedenis | E. coli |
Tmp may serve as a porin or transport protein for large molecules. TmpB Protein, Treponema phagedenis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 47.4 kDa and the accession number is P29720. | |||
TMPH-00487 |
EPOR Protein, Canine, Recombinant (His)
|
Canine | E. coli |
EPOR Protein, Canine, Recombinant (His) is expressed in E. coli. | |||
TMPY-01224 |
EPOR Protein, Mouse, Recombinant (His)
erythropoietin receptor |
Mouse | HEK293 Cells |
EPOR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P14753-1. | |||
TMPH-03640 |
34 kDa membrane antigen Protein, Treponema pallidum, Recombinant (His & Myc)
34 kDa membrane antigen,Pathogen-specific membrane antigen |
Treponema pallidum | E. coli |
This antigen is a pathogen-specific membrane immunogen. 34 kDa membrane antigen Protein, Treponema pallidum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.1 kDa and the accession number is P19478. | |||
TMPY-00521 |
EPOR Protein, Mouse, Recombinant (hFc)
erythropoietin receptor |
Mouse | Baculovirus Insect Cells |
EPOR Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 51.4 kDa and the accession number is P14753-1. | |||
TMPH-03641 |
TroA Protein, Treponema pallidum, Recombinant (His & Myc)
|
Treponema pallidum | E. coli |
Part of an ATP-driven transport system TroABCD for zinc. Substrate-binding protein involved in the transport of zinc across the cytoplasmic membrane. TroA Protein, Treponema pallidum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 38.2 kDa and the accession number is P96116. | |||
TMPH-00341 |
Canine distemper virus (strain Onderstepoort) Fusion glycoprotein F0 (His & SUMO)
F,Fusion glycoprotein F0 |
CDV | E. coli |
Canine distemper virus (strain Onderstepoort) Fusion glycoprotein F0 (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 67.5 kDa and the accession number is P12569. | |||
TMPH-03230 |
PHB depolymerase Protein, Ralstonia pickettii, Recombinant (His)
|
Ralstonia pickettii | E. coli |
This protein degrades water-insoluble and water-soluble PHB to monomeric D(-)-3-hydroxybutyrate. PHB depolymerase Protein, Ralstonia pickettii, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 50.9 kDa and the accession number is P12625. | |||
TMPH-03642 |
TP_0608 Protein, Treponema pallidum, Recombinant (His & Myc)
|
Treponema pallidum | E. coli |
N/A. TP_0608 Protein, Treponema pallidum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.5 kDa and the accession number is O83617. | |||
TMPJ-00235 |
TPO Protein, Human, Recombinant (His)
Megakaryocyte growth and development factor,C-mpl ligand,Thr... |
Human | HEK293 Cells |
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physi... | |||
TMPH-02312 |
Wilms tumor protein/WT1 Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may b... | |||
TMPY-04380 |
DYRK3 Protein, Human, Recombinant (His & GST)
REDK,RED,DYRK5,dual-specificity tyrosine-(Y)-phosphorylation... |
Human | Baculovirus Insect Cells |
Dual specificity tyrosine-phosphorylation-regulated kinase 3, also known as Regulatory erythroid kinase, REDK and DYRK3, is a nucleus protein which belongs to theprotein kinase superfamily, CMGC Ser/Thr protein kinase family and MNB/DYRK subfamily. DYRKs are an emerging family of dual-specificity kinases that play key roles in cell proliferation, survival, and development. DYRK3 contains oneprotein kinase domain. Isoform 1 and isoform 2 of DYRK3 are highly expressed in testis and in hemat... | |||
TMPY-04260 |
p38 Protein, Human, Recombinant (His)
mitogen-activated protein kinase 14,CSPB1,PRKM14,RK,p38α,CSB... |
Human | Baculovirus Insect Cells |
MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. MAPK14 can be detected in the brain, heart, placenta, pancreas, and skeletal muscle and it is expressed to a lesser extent in the lung, liver, and kidney. MAPK14 is activated by various environmental stresses ... | |||
TMPH-02274 |
JAK2 Protein, Human, Recombinant (His)
|
Human | E. coli |
Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple int... |