185
9
1
1
92
Cat. No. | Product Name | ||
---|---|---|---|
L9830 | 抗帕金森病化合物库 | 857 compounds | |
857 种帕金森病相关的化合物集合,可用于高通量和高内涵筛选; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
CL0114 |
ERK inhibitor kit
ERK inhibitor kit |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T28543 |
RK-9123016
RK9123016,RK 9123016 |
Sirtuin | Chromatin/Epigenetic; DNA Damage/DNA Repair |
RK-9123016是一种SIRT2抑制剂。RK-9123016增加真核翻译起始因子5A(eIF5A)(SIRT2的生理底物)的乙酰化水平,降低人乳腺癌细胞的细胞活力,同时降低c-Myc 表达。 | |||
T6970 |
RK33
RK-33,RK 33 |
COX | Immunology/Inflammation; Neuroscience |
RK33 (RK 33) 是 DDX3(一种 RNA 解旋酶)的一流小分子抑制剂,可导致 G1 细胞周期停滞,诱导细胞凋亡,并促进 DDX3 过表达细胞的辐射增敏。 | |||
T16761 |
RK-287107
|
Others; PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair; Others |
RK-287107 是一种有效且特异性的 tankyrase 抑制剂,可阻断结直肠癌细胞生长,对 tankyrase-1和 tankyrase-2的 IC50分别为 14.3 和 10.6 nM。 | |||
T16760 |
RK-24466
KIN 001-51 |
Src | Angiogenesis; Tyrosine Kinase/Adaptors |
RK-24466 (KIN 001-51) 是高效的、选择性的 Lck 抑制剂,对 Lck (64-509) 和 LckCD 亚型的 IC50 值分别为小于 1 和2 nM。 | |||
TQ0132 |
A 419259 trihydrochloride
RK 20449 trihydrochloride |
Src | Angiogenesis; Tyrosine Kinase/Adaptors |
A 419259 trihydrochloride (RK 20449 trihydrochloride) 是一种 Src 家族激酶抑制剂,能够抑制 Src (IC50:9 nM)、Lck (IC50:3 nM)、Lyn (IC50:3 nM)。 | |||
T20686 |
RK 397
RK397,RK-397 |
||
RK 397 is an antibiotic of oxopentaene macrolide. | |||
T34334 |
RK 29
RK29,RK-29 |
||
RK 29 has hypoxic cell sensitizer properties. | |||
T26099 |
RK-1441A
RK 1441A,RK1441A |
||
RK-1441A is an antibacteriophage antibiotic related to neothramycin. | |||
T26098 |
RK 286D
RK286D,RK-286D |
||
RK 286D is an indolocarbazole antibiotic. | |||
T26097 |
RK 1441B
RK-1441B,RK1441B |
||
RK 1441B is a bacteriophage antibiotic related to neothramycin. | |||
T71748 |
RK-0404678
|
||
RK-0404678 is a novel inhibitor of dengue virus NS5 RNA-dependent RNA polymerase (RdRp), inhibiting the DENV type 2 (DENV2) RdRp activities. | |||
T69839 |
RK-582
|
||
RK-582 is an orally efficacious spiroindolinone-based tankyrase inhibitor for the treatment of colon cancer. It exhibits a markedly improved robust tumor growth inhibition in a COLO-320DM mouse xenograft model when orally administered. | |||
T71819 |
RK-20448
|
||
RK-20448 is an ATP-competitive inhibitor of Lck, Src, KDR/VEGF2R, and Tie-2. It also inhibits BLK, Csk, Fyn, and Lyn. RK-20448 is the cis isomer of A-419259 | |||
T70523 |
RK-682
|
||
RK-682 is a natural selective inhibitor of protein tyrosine phosphatases (PTPases). | |||
T69885 | RK-52 | ||
RK-52 is a synthetic inhibitor of rhodesain, characterized by an impressive ksecond value (ksecond = 67000 × 103 M−1 min−1) and by a picomolar affinity toward the trypanosomal protease (Ki = 38 pM). | |||
T36367 |
RK-682 (calcium salt)
|
||
Protein tyrosine phosphatases (PTPs) remove phosphate from tyrosine residues of cellular proteins. Reversible phosphorylation catalyzed by the coordinated actions of protein tyrosine kinases and phosphatases is key to the regulation of the signaling events that control cell growth and proliferation, differentiation, and survival or apoptosis, as well as adhesion and motility. RK-682, a bioactive compound originally isolated from the fermentation of Streptomyces sp. 88-682, is an inhibitor of the... | |||
T41370 |
(Rac)-RK-682
|
||
(Rac)-RK-682 是 RK-682 的外消旋体。(Rac)-RK-682 是一种蛋白质酪氨酸磷酸酶 (PTPases) 抑制剂。(Rac)-RK-682 抑制蛋白酪氨酸磷酸酶 1B (PTP-1B)、低分子量蛋白酪氨酸磷酸酶 (LMW-PTP)、细胞分裂周期 25B (CDC-25B),IC50分别为 8.6 μM、12.4 μM 和 0.7 μM。 | |||
T73188 |
RK-0133114
|
||
RK-0133114 是G9a 抑制剂,也是RK-701 的 R-对映体。RK-0133114 抑制 G9a 的IC50值为 3.7 μM。RK-0133114 可用于镰状细胞病 (SCD) 的研究。 | |||
T10206 |
A 419259
RK-20449 |
Src | Angiogenesis; Tyrosine Kinase/Adaptors |
A 419259 is a pyrrolo-pyrimidine inhibitor, designed to enhance selectivity towards the Src family (IC50s: 9 nM, <3 nM and <3 nM for Src, Lck and Lyn). | |||
T69539 |
8RK64
|
||
8RK64 是一种共价的UCHL1抑制剂。 | |||
T73517 |
RK-701
|
||
RK-701 是一种G9a 高选择性且非遗传毒性的抑制剂,IC50值为 23-27 nM。RK-701 选择性的上调 HbF、γ- Globin、BGLT3 的表达,下调 H3K9me2 的表达。RK-701 也对 BCL11A 和 ZBTB7A 有抑制作用。 | |||
T69538 |
8RK59
|
||
8RK59 is a PARK7 inhibitor. | |||
T10188 |
6RK73
|
Others | Others |
6RK73 是一种共价不可逆的特异性 UCHL1 抑制剂,IC50 为 0.23 µM。6RK73 对 UCHL3 几乎没有抑制效果 (IC50=236 µM)。6RK73 特异性抑制乳腺癌中 UCHL1 的活性。 | |||
T70521 |
CGP-49823
|
||
CGP-49823 is a non-peptide tachykinin NK1 receptor antagonist. | |||
T69838 | NB-506 glucuronide | ||
NB-506 glucuronide is an indolocarbazole antitumor agent; a DNA topoisomerase I inhibitor. | |||
T69884 |
M122
|
||
M122 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent. | |||
T13360 |
XRK3F2
|
Autophagy | Autophagy |
XRK3F2 是 p62-ZZ 结构域的抑制剂,在体外减弱 MM 诱导的 Runx2 抑制,在体内肿瘤存在的情况下诱导新骨形成和重塑。 | |||
T2246 |
LRRK2-IN-1
5,11-二氢-2-[[2-甲氧基-4-[[4-(4-甲基-1-哌嗪基)-1-哌啶基]羰基]苯基]氨基]-5,11-二甲基-6H-嘧啶并[4,5-B][1,4]苯并二氮杂卓-6-酮 |
Apoptosis; LRRK2; CDK | Apoptosis; Autophagy; Cell Cycle/Checkpoint |
LRRK2-IN-1 是一种选择性的LRRK2有效抑制剂,作用于 LRRK2 (G2019S) 和 LRRK2 (WT),IC50值分别为 6 nM 和 13 nM。 | |||
T11226 |
ERK1/2 inhibitor 1
|
ERK | MAPK |
ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively. | |||
T72053 |
PERK-IN-6
|
PERK | Apoptosis |
PERK-IN-6 是一种新型高效的 PERK 抑制剂(IC50 : 2.5 nM)。 | |||
T63059 |
CRK12-IN-1
|
Antibiotic | Microbiology/Virology |
CRK12-IN-1 是一种有效的CRK12抑制剂。CRK12-IN-1具有杀虫活性, 对布氏锥虫 (T.b. brucei) 和刚果锥虫 (T. congolense) 具有抑制作用EC50分别为1.3和18 nM。CRK12-IN-1能迅速杀死病原细胞。 | |||
TP1606L |
NLS PKKKRKV acetate(95088-49-6 free base)
|
Others | Others |
NLS PKKKRKV acetate(95088-49-6 free base) 是从大猿病毒40肿瘤抗原(SV40大T 抗原)衍生的肽,是基因转移研究领域中增强核入口的一种方法。 | |||
T5535 |
ERK5-IN-2
|
ERK | MAPK |
ERK5-IN-2 是具有口服活性,亚微摩尔效力,选择性ERK5抑制剂,对ERK5和ERK5 MEF2D 的IC50s 分别是 0.82 和 3 μM。它抑制肿瘤异种移植生长和碱性成纤维细胞生长因子驱动的基质胶塞血管生成。 | |||
T9141 |
ERK-IN-3
ASN007 free base |
ERK | MAPK |
ERK-IN-3 (ASN007 free base) 是一种有效的口服活性 ERK 抑制剂,以低 IC50 值抑制 ERK1/2,可用于研究由 RAS 突变驱动的癌症。 | |||
T62957 |
MRK-740
|
Histone Methyltransferase | Chromatin/Epigenetic |
MRK-740 是一种具有高效性和选择性的 PRDM9 组蛋白甲基转移酶抑制剂。MRK-740 对其他组蛋白甲基转移酶具有抑制作用,抑制PRDM9依赖性的 H3K4 三甲基化 。 | |||
T16133 |
MRK-560
|
Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
MRK-560 是高效的、口服有效的 γ- 分泌酶抑制剂抑制剂,具有大脑屏障渗透性。 | |||
T74100 |
dAURK-4 hydrochloride
|
||
dAURK-4 hydrochloride,Alisertib 的衍生物,为高效选择性AURKA (Aurora A)降解剂,具备抗癌功能。 | |||
T10429 |
Tizaterkib
AZD-0364 |
ERK | MAPK |
Tizaterkib (AZD-0364) 是一种选择性ERK2抑制剂,IC50为 0.6 nM。 | |||
T10984 |
DDR-TRK-1
|
Discoidin Domain Receptor (DDR) | Tyrosine Kinase/Adaptors |
DDR-TRK-1 是 DDR1的一个选择性抑制剂,其 IC50 值为 9.4 nM。DDR-TRK-1 也抑制 TRK 激酶家族。 | |||
T77731 |
ERK5-IN-6
|
ERK | MAPK |
ERK5-IN-6 是一种有效的 ERK5 激酶抑制剂。ERK5-IN-6 具有抗增殖活性、抗惊厥活性和抗肿瘤活性,可用于研究中枢神经系统相关疾病。 | |||
T1898 |
RKI-1447
RKI1447 |
ROCK | Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells |
RKI-1447 是一种高效的ROCK1和ROCK2的小分子抑制剂,IC50值分别为14.5和6.2 nM。 | |||
T9609 |
GRK5-IN-2
|
GRK | GPCR/G Protein |
GRK5-IN-2 是基于吡啶的双环化合物,抑制 G 蛋白偶联受体激酶 5 。它调节胰岛素的表达和/或释放,在代谢疾病中有研究价值。 | |||
T10827 |
CK2/ERK8-IN-1
TMCB |
Apoptosis; ERK; Casein Kinase; Pim; DYRK | Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; JAK/STAT signaling; MAPK; Metabolism; Stem Cells; Tyrosine Kinase/Adaptors |
CK2/ERK8-IN-1 (TMCB) 是一种酪蛋白激酶 2 (CK2) (Ki 为 0.25 µM) 和 ERK8 (MAPK15, ERK7) 的双重抑制剂,IC50 均为 0.50 μM。CK2/ERK8-IN-1 也与 PIM1,HIPK2 和 DYRK1A 结合,Ki 值分别为 8.65 µM,15.25 µM 和 11.9 µM。 | |||
T77734 |
ERK5-IN-5
|
ERK | MAPK |
ERK5-IN-5 是一种有效的细胞外信号调节激酶 5 (ERK5)抑制剂,有抗癌活性和潜在的抗惊厥活性,抑制 A549 细胞增殖。 | |||
T11947 |
MARK4 inhibitor 1
|
Apoptosis; Others; AMPK | Apoptosis; Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling |
MARK4 inhibitor 1 是一种MARK4的抑制剂,IC50值为1.54 μM。它抑制癌细胞增殖、转移,诱导凋亡。 | |||
T63727 |
CRK12-IN-2
|
Parasite | Microbiology/Virology |
CRK12-IN-2 是一种有效的 CRK12 的抑制剂。CRK12-IN-2 对寄生虫具有抑制作,对Trypanosoma congolense 和 Trypanosoma vivax 的 EC50 值分别为 3.2 和 0.08 nM。CRK12-IN-2 可用于预防和治疗动物锥体虫病。 | |||
T61556 |
GRK6-IN-2
|
GRK | GPCR/G Protein |
GRK6-IN-2 是一种高效的 G 蛋白偶联受体激酶 6 (GRK6)抑制剂,具有潜在的抗肿瘤活性。GRK6-IN-2具有研究多发性骨髓瘤。 | |||
T2011 |
RKI1313
RKI 1313,RKI-1313 |
ROCK | Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells |
RKI1313 (RKI-1313) 是一种选择性抑制剂,可抑制 ROCK 依赖性信号传导、细胞骨架变化、不依赖锚定的集落形成、迁移和侵袭。 | |||
T14364 |
AZ-Dyrk1B-33
3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine |
DYRK | Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors |
AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) 是高选择性的Dyrk1B 激酶抑制剂,其IC50=7 nM。 | |||
T2414 |
Torkinib
PP 242 |
Apoptosis; Mitophagy; PI3K; mTOR; Autophagy | Apoptosis; Autophagy; PI3K/Akt/mTOR signaling |
Torkinib (PP 242) 是一种选择性,ATP 竞争型的mTOR 抑制剂,IC50为 8 nM。它也抑制mTORC1和mTORC2,IC50分别为 30 nM 和 58 nM。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6S1495 |
Ginsenoside Rk3
人参皂苷Rk3,人参皂甙 Rk3 |
Others; NF-κB | NF-κB; Others |
Ginsenoside Rk3 是存在于 Panax notoginseng 的根中。它能够抑制 HepG2 细胞中 TNF-α 诱导的 NF-κB 转录活性,IC50=14.24±1.30 μM。 | |||
TN1095 |
Ginsenoside Rk2
人参皂苷RK2 |
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities. | |||
T4S1499 |
Ginsenoside Rk1
人参皂苷RK1,人参皂苷 |
Apoptosis; Others; NF-κB; PI3K; JAK | Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; NF-κB; Others; PI3K/Akt/mTOR signaling; Stem Cells |
Ginsenoside Rk1 是人参的高温加工提取物,抑制Jak2/Stat3信号通路和NF-κB 的激活。它具有抗肿瘤、抗血小板聚集活性、抗炎、抗胰岛素抵抗、肾保护和抗菌作用,可使认知功能增强,脂质积聚减少和预防骨质疏松症,还诱导细胞凋亡。 | |||
TN2287 |
Turkesterone
|
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Turkesterone is a phytoecdysteroid possessing an 11alpha-hydroxyl group, also is an analogue of the insect steroid hormone 20-hydroxyecdysone. It has immunomodulating and antistress activity, can increase the adaptation capacity of mice under immobilization-induced stress conditions. | |||
TN4669 |
Norkhellol
|
Others | Others |
Norkhellol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4669,CAS号为 4439-68-3。 | |||
T20635 |
Senkirkin
Renardin |
||
Senkirkin is a pyrrolizidine alkaloid with hepatotoxicity. | |||
T79951 |
Piperkadsin A
|
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
Piperkadsin A作为一种ROS抑制剂,能够有效地抑制PMA诱导的人多形核中性粒细胞中ROS的生成,其IC50值为4.3 μM。 | |||
T81859 |
Markogenin
|
||
Markogenin为一Yucca shidgera所源甾类化合物。 | |||
T2S0633 |
Raspberry ketone
Oxyphenalon,Rasketone,Aloenin,4-(4-Hydroxyphenyl)-2-butanone,p-Hydroxybenzyl acetone,Frambinone,覆盆子酮 |
PPAR | DNA Damage/DNA Repair; Metabolism |
Raspberry ketone (p-Hydroxybenzyl acetone) 是覆盆子中主要的芳香族天然产物,主要用作化妆品的香料和食品增味剂,也可作 PPAR-α激动剂。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04260 |
p38 Protein, Human, Recombinant (His)
mitogen-activated protein kinase 14,CSPB1,PRKM14, |
Human | Baculovirus Insect Cells |
MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. MAPK14 can be detected in the brain, heart, placenta, pancreas, and skeletal muscle and it is expressed to a lesser extent in the lung, liver, and kidney. MAPK14 is activated by various environmental stresses ... | |||
TMPY-00751 |
TrkB Protein, Human, Recombinant (His)
trk-B,GP145-TrkB/GP95-TrkB,neurot... |
Human | HEK293 Cells |
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2. | |||
TMPY-02231 |
TrkB Protein, Mouse, Recombinant (His)
trk-B,neurotrophic tyrosine kinase, receptor, type ... |
Mouse | HEK293 Cells |
TrkB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15209-2. | |||
TMPY-01129 |
Influenza A H5N1 (A/Vietnam/1194/2004) Hemagglutinin/HA Protein (RERRRKKR to TETR, HA1+HA2, uncleaved, His)
Harvey rat sarcoma viral oncogene homolog |
H5N1 | HEK293 Cells |
Influenza A H5N1 (A/Vietnam/1194/2004) Hemagglutinin/HA Protein (RERRRKKR to TETR, HA1+HA2, uncleaved, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is Q6DQ34. | |||
TMPJ-01464 |
IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)
TCGF,Aldesleukin,T-Cell Growth Factor,IL-2,Interleukin-2,IL2 |
Human | HEK293 Cells |
Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system,belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages... | |||
TMPY-04751 |
VRK1 Protein, Human, Recombinant
PCH1,vaccinia related kinase 1,PCH1A |
Human | Baculovirus Insect Cells |
VRK1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 45.6 kDa and the accession number is Q99986. | |||
TMPY-01084 |
TrkA Protein, Human, Recombinant (His)
TRK1,TRK,TRKA,neurotrophic tyrosi... |
Human | HEK293 Cells |
TrkA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.5 kDa and the accession number is P04629-1. | |||
TMPY-00146 |
RKIP/PEBP1 Protein, Human, Recombinant
PBP,HEL-S-34,PEBP,RKIP,HCNP,PEBP-1,phosphatidyletha... |
Human | E. coli |
Phosphatidylethanolamine-binding protein 1 (PEBP1), also known as Raf kinase inhibitor protein, belongs to PEBP family of proteins. It is known to interact with many proteins that are mainly involved in pathways that monitor cell proliferation and differentiation. PEBP1 in many cells interacts with several pathways, namely MAPK, GRK2, NF-small ka, CyrillicB, etc. that keeps the cell proliferation and differentiation in check. This protein is expressed by many cells in humans, including neurons w... | |||
TMPH-02461 |
pylS Protein, Methanosarcina barkeri, Recombinant (His)
|
Methanosarcina barkeri | E. coli |
Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG. pylS Protein, Methanosarcina barkeri, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 51.8 kDa and the accession number is Q46E77. | |||
TMPY-04440 |
Brk Protein, Mouse, Recombinant (His & GST)
BRK,Tksk,protein tyrosine kinase 6,tks,Sik |
Mouse | Baculovirus Insect Cells |
Brk Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 79.8 kDa and the accession number is Q64434. | |||
TMPK-00774 |
TrkA Protein, Human, Recombinant (aa 33-417, His)
TrkAI,TrkA I,Trk-A,TRKA,... |
Human | HEK293 Cells |
TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces receptor autophosphorylation and activation of intracellular signaling pathways, resulting in diverse biological effects. | |||
TMPY-03162 |
TrkB Protein, Rat, Recombinant (His)
neurotrophic tyrosine kinase, receptor, type 2 |
Rat | HEK293 Cells |
TrkB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.1 kDa and the accession number is Q63604. | |||
TMPY-04406 |
Protein Kinase D2/PRKD2 Protein, Human, Recombinant (His & GST)
protein kinase D2,nPKC-D2,PKD2,HSPC187 |
Human | Baculovirus Insect Cells |
Serine/threonine-protein kinase D2, also known as PRKD2 and PKD2, is a cytoplasm and membrane protein that belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and PKD subfamily. PRKD2 / PKD2 is widely expressed. It contains one PH domain, two phorbol-ester/DAG-type zinc fingers and one protein kinase domain. PRKD2 / PKD2 is activated by DAG and phorbol esters. Phorbol-ester/DAG-type domains bind DAG, mediating translocation to membranes. Autophosphorylation of Ser-71 an... | |||
TMPY-04292 |
Influenza A H5N1 (A/Hong kong/213/2003) Hemagglutinin/HA Protein (S28W, RRRKKR to TETR, His)
Harvey rat sarcoma viral oncogene homolog |
H5N1 | Baculovirus Insect Cells |
Influenza A H5N1 (A/Hong kong/213/2003) Hemagglutinin/HA Protein (S28W, RRRKKR to TETR, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.9 kDa and the accession number is Q4H2E2. | |||
TMPY-04409 |
GRK6 Protein, Human, Recombinant (His & GST)
G protein-coupled receptor kinase 6,GPRK6 |
Human | Baculovirus Insect Cells |
G protein-coupled receptor kinase 6, also known as G protein-coupled receptor kinase GRK6, GRK6, and GPRK6, is a lipid-anchor protein that belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family, and GPRK subfamily. GRK6 / GPRK6 contains one AGC-kinase C-terminal domain, one protein kinase domain, and one RGS domain. This protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding differen... | |||
TMPY-03470 |
TrkA Protein, Mouse, Recombinant (hFc)
TrkA,C80751,neurotrophic tyrosine kinase, receptor,... |
Mouse | HEK293 Cells |
TrkA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69.2 kDa and the accession number is Q3UFB7. | |||
TMPY-04771 |
CARKL Protein, Human, Recombinant (His & GST)
SHK,CARKL,sedoheptulokinase |
Human | Baculovirus Insect Cells |
CARKL, also known as SHPK, is a nonprotein kinase of glucose metabolism. CARKL has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. CARKL catalyzes an orphan reaction in the pentose phosphate pathway, refocusing cellular metabolism to a high-redox state upon physiological or artificial downregulation. CARKL-dependent metabolic reprogramming is required for proper M1- and ... | |||
TMPY-03560 |
TrkA Protein, Rat, Recombinant (hFc)
neurotrophic tyrosine kinase, receptor, type 1 |
Rat | HEK293 Cells |
TrkA Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69.2 kDa and the accession number is P35739. | |||
TMPJ-01112 |
PRKG1 Protein, Human, Recombinant (His)
PRKGR1B,PRKG1B,cGKI,cGMP-Dependent Protein... |
Human | HEK293 Cells |
cGMP-Dependent Protein Kinase 1 (PRKG1) belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. PRKG1 contains one AGC-kinase C-terminal domain, two cyclic nucleotide-binding domains, and one protein kinase domain. PRKG1 is mainly expressed in the lung and placenta. PRKG1 acts as a key mediator of the nitric oxide (NO)/cGMP signaling pathway. PRKG1 can phosphorylate many proteins that regulate platelet activation and adhesion, smooth muscle contraction, cardiac function,... | |||
TMPH-03408 |
NirK Protein, Rhizobium sullae, Recombinant (His)
|
Rhizobium sullae | E. coli |
NirK Protein, Rhizobium sullae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.8 kDa and the accession number is Q60214. | |||
TMPY-01128 |
Influenza A H5N1 (A/turkey/Turkey/1/2005) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H5N1 | HEK293 Cells |
Influenza A H5N1 (A/turkey/Turkey/1/2005) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is Q207Z6. | |||
TMPY-03712 |
TrkA Protein, Canine, Recombinant (His)
neurotrophic tyrosine kinase, receptor, type 1 |
Canine | HEK293 Cells |
TrkA Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is XP_851619.3. | |||
TMPY-04560 |
VRK1 Protein, Human, Recombinant (His & GST)
PCH1A,PCH1,vaccinia related kinase 1 |
Human | Baculovirus Insect Cells |
VRK1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 73 kDa and the accession number is Q99986. | |||
TMPY-00202 |
Influenza A H5N8 (A/turkey/Ireland/1378/1983) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H5N8 | HEK293 Cells |
Influenza A H5N8 (A/turkey/Ireland/1378/1983) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.8 kDa and the accession number is P11135. | |||
TMPY-05872 |
Influenza A H1N1 (A/swine/Denmark/12813-1/2004) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N1 | HEK293 Cells |
Influenza A H1N1 (A/swine/Denmark/12813-1/2004) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is U5JC06. | |||
TMPY-04840 |
Influenza A H5N8 (A/turkey/Germany-MV/R2472/2014) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H5N8 | Baculovirus Insect Cells |
Influenza A H5N8 (A/turkey/Germany-MV/R2472/2014) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 60.1 kDa. | |||
TMPY-01702 |
Influenza A H5N1 (A/Hong kong/213/2003) Hemagglutinin/HA Protein (S28W, RRRKKR to TETR, uncleaved, His)
Harvey rat sarcoma viral oncogene homolog |
H5N1 | HEK293 Cells |
Influenza A H5N1 (A/Hong kong/213/2003) Hemagglutinin/HA Protein (S28W, RRRKKR to TETR, uncleaved, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is Q4H2E2. | |||
TMPY-01759 |
TrkA Protein, Human, Recombinant (aa 285-413, His)
neurotrophic tyrosine kinase, receptor, type 1,p140-Trk<... |
Human | E. coli |
TrkA Protein, Human, Recombinant (aa 285-413, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 15.1 kDa and the accession number is P04629-1. | |||
TMPY-01526 |
Influenza A H5N1 (A/Cambodia/R0405050/2007) Hemagglutinin/HA Protein (HA1+HA2, uncleaved, GRRKKR to TETR, aa 1-531, His)
Harvey rat sarcoma viral oncogene homolog |
H5N1 | HEK293 Cells |
Influenza A H5N1 (A/Cambodia/R0405050/2007) Hemagglutinin/HA Protein (HA1+HA2, uncleaved, GRRKKR to TETR, aa 1-531, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is B6EBW8. | |||
TMPK-00677 |
PKA/PRKACA Protein, Canine, Recombinant (His)
PKA C alpha,PKACA,PPNAD4,PKA C α,PKA C-α,PKA C-alpha,PRK... |
Canine | E. coli |
The cAMP-dependent protein kinase PKA is a well-characterized member of the serine-threonine protein AGC kinase family and is the effector kinase of cAMP signaling. As such, PKA is involved in the control of a wide variety of cellular processes including metabolism, cell growth, gene expression and apoptosis. cAMP-dependent PKA signaling pathways play important roles during infection and virulence of various pathogens. Since fluxes in cAMP are involved in multiple intracellular functions, a vari... | |||
TMPY-05207 |
PRKAR1A Protein, Mouse, Recombinant (His)
1300018C22Rik,protein kinase, cAMP-dependent, regulatory, ty... |
Mouse | Baculovirus Insect Cells |
PRKAR1A Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 44.6 kDa and the accession number is Q9DBC7. | |||
TMPY-04174 |
Influenza A H7N3 (A/turkey/Italy/214845/2002) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H7N3 | HEK293 Cells |
Influenza A H7N3 (A/turkey/Italy/214845/2002) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q701U0. | |||
TMPH-00318 |
LpxD Protein, Burkholderia pseudomallei, Recombinant (His & Myc)
|
Burkholderia pseudomallei | E. coli |
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. LpxD Protein, Burkholderia pseudomallei, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 44.2 kDa and the accession number is A3NAT7. | |||
TMPH-02478 |
PRKAA1 Protein, Mouse, Recombinant (His)
|
Mouse | Baculovirus Insect Cells |
PRKAA1 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with N-6xHis tag. The predicted molecular weight is 65 kDa and the accession number is Q5EG47. | |||
TMPY-03656 |
PRKAR1A Protein, Human, Recombinant (His)
PRKAR1,CAR,CNC1,PPNAD1,CNC,protein kinase, cAMP-dep... |
Human | HEK293 Cells |
PRKAR1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is P10644. | |||
TMPH-02480 |
PRKAB1 Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
PRKAB1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 36.1 kDa and the accession number is Q9R078. | |||
TMPY-00923 |
SLITRK1 Protein, Human, Recombinant (His)
TTM,FLJ54428,LRRC12,RP11-395N17.1,KIAA0918,SLITRK1,... |
Human | HEK293 Cells |
SLITRK1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 105-115 kDa and the accession number is Q96PX8. | |||
TMPH-02481 |
PRKAG1 Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
PRKAG1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 41.6 kDa and the accession number is O54950. | |||
TMPY-00370 |
Influenza A H7N1 (A/turkey/Italy/4602/99) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H7N1 | HEK293 Cells |
Influenza A H7N1 (A/turkey/Italy/4602/99) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q7TAW6. | |||
TMPH-01263 |
PRKN Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, MIRO1 and AIMP2. Mediates monoubiquitination as well as 'Lys-6', 'Lys-11', 'Lys-48'-linked and 'Lys-63'-linked polyubiquitination of substrates depending on the context. Participates in the removal and/or det... | |||
TMPY-06967 |
TrkA Protein, Cynomolgus, Recombinant (His)
neurotrophic tyrosine kinase, receptor, type 1 |
Cynomolgus | HEK293 Cells |
TrkA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.95 kDa and the accession number is XP_005541454.3. | |||
TMPY-03063 |
SLITRK6 Protein, Human, Recombinant (His)
SLIT and NTRK like family member 6,SLITRK6... |
Human | HEK293 Cells |
SLITRK6 belongs to the SLITRK family. Members of this family share two conserved leucine-rich repeat domains in the extracellular domain. SLITRK6 contains 11 LRR (leucine-rich) repeats, 2 LRRCT domains and 2 LRRNT domains. Expression of SlITRK proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. SLITRK6 is highly expressed in putamen with no expression in cerebral cortex. It also can be detected in adult and fetal lung and fetal liver. It can sup... | |||
TMPH-02540 |
GRK2 Protein, Mouse, Recombinant (His & SUMO)
|
Mouse | E. coli |
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and... | |||
TMPY-04571 |
ERK2 Protein, Mouse, Recombinant (His & GST)
PRKM2,C78273,mitogen-activated protein kinase 1,AU0... |
Mouse | Baculovirus Insect Cells |
ERK2 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.1 kDa and the accession number is P63085. | |||
TMPY-04562 |
GRK2 Protein, Human, Recombinant (His & GST)
β,adrenergic, beta, receptor kinase 1 |
Human | Baculovirus Insect Cells |
G-protein coupled receptor kinase 2 (GRK2), also referred as Adrenergic, beta, receptor kinase 1 (ADRBK1), is a ubiquitous member of the G protein-coupled receptor kinase (GRK) family that appears to play a central, integrative role in signal transduction cascades. GRK2 can phosphorylate a growing number of non-GPCR substrates and associate with a variety of proteins related to signal transduction, thus suggesting that this kinase could also have diverse 'effector' functions. GRK2 has been repor... | |||
TMPY-02484 |
SLITRK4 Protein, Human, Recombinant (His)
DKFZp547M2010,SLIT and NTRK like family member 4 |
Human | HEK293 Cells |
SLIT and NTRK-like family proteins 4 is a member of the SLIT and NTRK-like family. This protein is characterized as an integral membrane protein that has two leucine-rich repeat (LRR) domains and a carboxy-terminal domain that is partially similar to SLIT protein and TRK Neurotrophin There are six members in this family: SLITRK1, SLITRK2, SLITRK3, SLITRK4, SLITRK5, and SLITRK6. Their expression was detected mainly in the brain, but the expression profile of each SLITRK was unique. Each of these ... | |||
TMPH-02899 |
VRK1 Protein, Mouse, Recombinant (His & Myc)
|
Mouse | E. coli |
VRK1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-6xHis and C-Myc tag. The predicted molecular weight is 55.2 kDa and the accession number is Q80X41. | |||
TMPY-00485 |
Olfactory Marker Protein Protein, Human, Recombinant (His)
OMP,olfactory marker protein |
Human | E. coli |
OMP (Olfactory Marker Protein) is a Protein Coding gene. OMP is a protein expressed in the mature olfactory and vomeronasal neurons of many vertebrates, such as mammals, amphibians, and bony fishes. Its structure and protein sequence are highly conserved between the mouse, rat, and human. OMP is a ubiquitous, cytoplasmic protein found in mature olfactory receptor neurons of all vertebrates. It participates in the olfactory signal transduction pathway. OMP expression is a hallmark of mature verte... | |||
TMPH-01262 |
PRKN Protein, Human, Recombinant (His & Myc)
|
Human | Baculovirus Insect Cells |
PRKN Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 55.6 kDa and the accession number is O60260. | |||
TMPY-01385 |
Influenza A H1N1 (A/New York/18/2009) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H1N1 | Baculovirus Insect Cells |
Influenza A H1N1 (A/New York/18/2009) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59 kDa and the accession number is C3W6C4. | |||
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