218
10
8
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6355 |
(R)-baclofen
STX209,Arbaclofen,(R)-巴氯芬 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
(R)-baclofen (STX209) 是一种选择性GABAB 受体激动剂。 | |||
T5843L |
(S)-Flurbiprofen
esflurbiprofen,(S)-氟比洛芬 |
COX; PGE Synthase | Immunology/Inflammation; Neuroscience |
Esflurbiprofen 是 Flurbiprofen 的活性对映体,是 COX-1 和 COX-2 的抑制剂,对 COX-1和 COX-2的 IC50分别为0.48 和 0.47 μM。 | |||
T11071 |
Dofequidar fumarate
MS-209 |
P-gp | Membrane transporter/Ion channel; Neuroscience |
Dofequidar fumarate (MS-209) 是口服活性的喹啉化合物,通过抑制 ABCB1/P-gp 和 ABCC1/MDR 相关蛋白 1 来克服 MDR。 | |||
T25956 |
Piketoprofen
Calmatel |
Others | Others |
Piketoprofen (Calmatel) 是一种局部非甾体抗炎药。 | |||
T4384 |
Halofenozide
|
Others | Others |
Halofenozide 是一种新的昆虫生长调节剂 (IGR),具有苯甲酰肼结构,也是一种蜕皮激素 (ecdysteroid) 激动剂。可模拟天然昆虫蜕皮激素 20-羟基蜕皮激素的作用, | |||
T16022 |
Arhalofenate
JNJ 39659100,芳卤芬酯,4-氯-ALPHA-[3-(三氟甲基)苯氧基]苯乙酸 2-(乙酰基氨基)乙酯,MBX 102 |
PPAR | DNA Damage/DNA Repair; Metabolism |
Arhalofenate (JNJ 39659100) 是一种选择性的(PPAR)-γ部分激动剂,用于研究 2 型糖尿病。 | |||
T4466 |
Pitofenone hydrochloride
Baralgin Ketone Hydrochloride,Pitophenone hydrochloride,吡托非农盐酸盐 |
AChE | Neuroscience |
Pitofenone hydrochloride (Pitophenone hydrochloride) 是一种能够抑制乙酰胆碱酯酶活性的解痉化合物,对于来自牛红细胞和电鳗的乙酰胆碱酯酶的Ki 分别为 36 和 45 μM。 | |||
T0839 |
Ketoprofen
酮基布洛芬,RP-19583,酮洛芬 |
Apoptosis; COX; MRP | Apoptosis; Immunology/Inflammation; Neuroscience |
Ketoprofen (RP-19583) 是一种非甾体抗炎剂,能够有效地抑制COX 的活性,在人血单核细胞中,对 COX-1 和 COX-2 的IC50值分别为 2 nM 和 26 nM。 | |||
T4440 |
Saclofen
|
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Saclofen 是竞争性GABAB 受体拮抗剂(IC50:7.8 μM)。它可研究 GABAB 受体调节大脑中缓慢抑制性突触后电位的功能。 | |||
T0291 |
Flurbiprofen
氟比洛芬,dl-Flurbiprofen |
Apoptosis; COX; MRP | Apoptosis; Immunology/Inflammation; Neuroscience |
Flurbiprofen (dl-Flurbiprofen) 是一种高效的,具有口服活性的非甾体抗炎化合物,有退热止痛活性, 常用于炎症性疾病的研究。它是一种非选择性的环氧合酶抑制剂,可研究结肠癌。 | |||
T6476 |
Dofetilide
UK 68789,UK-68798,Tikosyn,多非利特 |
Potassium Channel | Membrane transporter/Ion channel |
Dofetilide (UK 68789) 是一种具有口服活性、有效的且特异性的IKr 阻滞剂,作为 III 类抗心律失常药物。Dofetilide 可用于心血管疾病研究。 | |||
T6470 |
Diclofenac Potassium
双氯芬酸钾,CGP-45840B,Cataflam,Voltfast |
Apoptosis; Others; COX | Apoptosis; Immunology/Inflammation; Neuroscience; Others |
Diclofenac Potassium (CGP-45840B) 是一种非甾体抗炎药,用于减轻炎症并在某些情况下作为镇痛剂减轻疼痛。它通过活化 caspase 级联反应来诱导神经干细胞凋亡。它是一种COX 抑制剂,在 CHO 细胞中,对人 COX-1 和 COX-2 的IC50值分别为 4 和 1.3 nM。它对绵羊 COX-1 和 COX-2 的IC50值分别为 5.1 μM 和0.84 μM。 | |||
T5030 |
Zofenopril calcium
SQ26991,佐芬普利钙,Zofenopril (calcium) |
RAAS; Reactive Oxygen Species | Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB |
Zofenopril calcium (SQ26991) 是一种抗氧化剂和血管紧张素转化酶 (ACE) 抑制剂。 | |||
T4994 |
Tocofersolan
Vitamin E-TPGS,Tocophersolan,TPGS,D-α-Tocopherol polyethylene glycol 1000 succinate,托可索仑,维生素E聚乙二醇琥珀酸酯 |
Others | Others |
Tocofersolan (TPGS) 是合成的 α-生育酚的聚乙二醇衍生物。 | |||
T36683 |
Vedaprofen
Quadrisol,PM 150,维达洛芬,CERM 10202 |
COX; Antibacterial; Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience |
Vedaprofen (PM 150) 抑制 COX-1 并通过抗炎活性减少前列腺素 H2 的合成。 Vedaprofen 是一种大肠杆菌滑动钳抑制剂,IC50 为 222 μM,Ki 为 131 μM。 | |||
T0321 |
Indoprofen
吲哚洛芬,(±)-Indoprofe,茚酮苯丙酸 |
COX | Immunology/Inflammation; Neuroscience |
Indoprofen ((±)-Indoprofe) 是非甾体类抗炎药, 可用于研究脊髓性肌萎缩。 | |||
T0184 |
Fenoprofen calcium dihydrate
|
COX | Immunology/Inflammation; Neuroscience |
Fenoprofen calcium dihydrate 是一种丙酸衍生物,用作非甾体抗炎剂。 | |||
T50053 |
Lofemizole
|
P450 | Metabolism |
Lofemizole 是 CYP1A2 的拮抗剂。 | |||
T1065 |
Baclofen
巴氯芬,Lioresal |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Baclofen (Lioresal) 是 γ-氨基丁酸 (GABA) 的亲脂性衍生物,是可口服的选择性代谢型 GABA-B 受体激动剂,具有高血脑屏障渗透率,用于治疗因脊髓损伤和多发性硬化引起的痉挛。 | |||
T6540 |
Ibuprofen Lysine
布洛芬赖氨酸盐,Neoprofen |
COX | Immunology/Inflammation; Neuroscience |
Ibuprofen Lysine (Neoprofen) 是一种非甾体抗炎药。 | |||
T12987 |
Spirodiclofen
BAJ-2740,螺螨酯 |
Parasite | Microbiology/Virology |
Spirodiclofen (BAJ-2740) 是选择性非系统性的杀螨剂,来自新的化学类特酮酸衍生物, 与目前市面上的杀螨剂无交叉耐药, 具有额外的杀虫性能。 | |||
T8364 |
Mebrofenin
N-(3-溴-2,4,6-三甲基苯基甲酰甲基)乙酰乙酸,SQ 26962 |
Others | Others |
Mebrofenin (SQ 26962) 是一种亚氨基二乙酸 (IDA) ,可用作 Tc-99m 的放射性标记试剂盒。其中Tc-99m Mebrofenin 是一种诊断剂,用于肝胆显像,也是评价肝功能的首选放射性药物。 | |||
T6568 |
Licofelone
利克飞龙,ML-3000 |
Apoptosis; Lipoxygenase; COX | Apoptosis; Immunology/Inflammation; Metabolism; Neuroscience |
Licofelone (ML-3000) 是一种 COX/LOX 双重抑制剂,IC50分别为 0.21和0.18 μM,有潜力研究骨关节炎,具有抗炎和抗增殖作用。它可诱导细胞凋亡,减少促炎性白三烯和前列腺素的产生。 | |||
T0643 |
Diclofenac Amide
|
Others | Others |
Diclofenac Amide 用作Diclofenac 的中间体。 | |||
T15300 |
Fluorofenidone
AKF-PD |
Others | Others |
Fluorofenidone (AKF-PD) 是 AMR69 的类似物,抗纤维化活性与 AMR69相同,但 Fluorofenidone 的毒性更低,半衰期长。它部分通过 PI3K/Akt 信号通路抑制 NADPH 氧化酶和细胞外基质 (ECM) 的沉积,能够减少肾间质纤维化的发生。 | |||
T37482 |
Diclofenac methyl ester
|
Others | Others |
Diclofenac methyl ester 是双氯芬酸(diclofenac)的疏水性前药形式,它是一种非甾体抗炎药 (NSAID)。它比双氯芬酸更易溶于肉豆蔻酸异丙酯,但毒性更高。 | |||
T16329 |
Nitroflurbiprofen
NO-flurbiprofen,Nitroxybutyl flurbiprofen,硝基氟比洛芬,HCT 1206 |
COX | Immunology/Inflammation; Neuroscience |
Nitroflurbiprofen (Nitroxybutyl flurbiprofen) 是一种释放 NO 的环氧合酶抑制剂,可调节门脉高压性肝硬化大鼠肝内血管张力的增加。 | |||
T1185 |
Rofecoxib
MK 966,罗非昔布,罗非考昔,MK-0966 |
COX | Immunology/Inflammation; Neuroscience |
Rofecoxib (MK 966) 是可口服的 COX-2特异性抑制剂,具有抗炎、解热和镇痛特性以及潜在的抗肿瘤特性。在人骨肉瘤细胞和中国仓鼠卵巢细胞中,对人 COX-2 的 IC50值分别为 26 和 18 nM。 | |||
T5460 |
Mofezolac
莫苯唑酸,莫非佐酸 |
COX | Immunology/Inflammation; Neuroscience |
Mofezolac 是一种非甾体类抗炎药,可缓解疼痛并具有抗炎活性,抑制 COX-1和COX-2的IC50为 1.44 和 447 nM。 | |||
T2553 |
Etofenamate
|
COX | Immunology/Inflammation; Neuroscience |
Etofenamate 是非甾体类抗炎小分子,也是非选择性的 COX 抑制剂,具有抗风湿和解热抗炎作用,可用于缓解疼痛、关节炎等炎症相关疾病的研究。 | |||
T0463 |
Loxoprofen
Loxoprofene,洛索洛芬,Loxoprofeno,Koloxo |
COX | Immunology/Inflammation; Neuroscience |
Loxoprofen (Koloxo) 是一种非甾体类抗炎药,具有解热作用,可用于缓解疼痛的研究。它是非选择性COX 抑制剂,对 COX-1 和 COX-2 的IC50分别为 6.5 和 13.5 μM。 | |||
T0159 |
Pranoprofen
普拉洛芬,Pyranoprofen |
Apoptosis; COX; PGE Synthase; Prostaglandin Receptor | Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Pranoprofen (Pyranoprofen) 可抑制COX1/2酶,阻断花生四烯酸转化为二十烷醇,减少前列腺素的合成。它是一种用于眼科的非甾体抗炎试剂。 | |||
T0196 |
Diclofenac
双氯芬酸,奥尔芬,Diclofenacum,Voltaren |
Apoptosis; COX | Apoptosis; Immunology/Inflammation; Neuroscience |
Diclofenac (Diclofenacum) 是一种具有抗炎活性的非甾体苯乙酸衍生物,是 COX 抑制剂,在 CHO 细胞中,对人 COX-1 和 COX-2 的 IC50值分别为 4 和 1.3 nM。它对绵羊 COX-1 和 COX-2 的 IC50值分别为 5.1 μM,0.84 μM。它通过活化 caspase 级联反应来诱导神经干细胞凋亡。 | |||
T6687 |
Suprofen
Maldocil,Suprol,TN-762,舒洛芬,Profenal |
COX; PGE Synthase | Immunology/Inflammation; Neuroscience |
Suprofen (Suprol) 是一种非甾体抗炎化合物,对前列腺素合成具有抑制作用。 | |||
T7363 |
Ibuprofen Piconol
U75630,匹美诺芬,布洛芬吡啶甲醇 |
Others | Others |
Ibuprofen Piconol (U75630) 是非甾体抗炎药物,局部使用可缓解原发性热灼伤和晒伤。 | |||
T6497 |
Fenoprofen Calcium
|
Others; COX | Immunology/Inflammation; Neuroscience; Others |
Fenoprofen Calcium 是一种非甾体类抗炎药,可治疗关节炎。 | |||
T34268 |
Raxofelast
IRFI016,IRFI-016,IRFI 016 |
||
Raxofelast (IRFI-016) 具有治疗糖尿病并发症和动脉粥样硬化的潜力 | |||
T27572 |
Ibuprofen diethylaminoethyl ester
Brufen diethylaminoethyl ester,BF-DEAE,BF DEAE |
Others | Others |
Ibuprofen diethylaminoethyl ester (BF DEAE) 具有抗炎活性,可作为局部麻醉剂,可用于研究麻风性神经炎等神经系统疾病。 | |||
T3496 |
Buprofezin
噻嗪酮,NNI 750,Applaud,Buprofezine |
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
Buprofezin (Applaud) 是一种杀虫剂,通过抑制几丁质合成起作用,在体外还可以剂量依赖性地增加活性氧的产生。 | |||
T19679 |
Benoxaprofen
氧苯恶唑丙酸,NSC 299582,LY-90459,Benoxaphen. Compound 90459 |
COX | Immunology/Inflammation; Neuroscience |
Benoxaprofen (NSC-299582) 是长效的、强效的抗炎和解热化合物,在体外具有较弱的对环氧合酶的抑制作用,也可以抑制脂氧合酶,在一些炎症动物模型中抑制单核细胞迁移。 | |||
T39280 |
Nitrofen
|
Others | Others |
Nitrofen 是选择性接触除草剂,也是视原卟啉原氧化酶和网膜脱氢酶抑制剂。 | |||
T9472 |
Rebamipide mofetil
|
COX | Immunology/Inflammation; Neuroscience |
Rebamipide mofetil 是 Rebamipide 的口服活性前药,是一种粘膜保护剂。 | |||
T1555 |
Diclofenac sodium
GP 45840,双氯芬酸钠 |
Apoptosis; COX | Apoptosis; Immunology/Inflammation; Neuroscience |
Diclofenac sodium (GP 45840) 是一种非选择性抗炎剂,是 COX 抑制剂,在 CHO 细胞中,对人 COX-1 和 COX-2 的 IC50值分别为 4 和 1.3 nM。它对绵羊 COX-1 和 COX-2 的 IC50值分别为 5.1 μM,0.84 μM。它通过活化 caspase 级联反应来诱导神经干细胞凋亡。 | |||
T6053 |
Turofexorate Isopropyl
XL335,FXR-450,WAY-362450,妥芬异丙酯 |
FXR; Autophagy | Autophagy; Metabolism |
Turofexorate Isopropyl (XL335) 是一种口服有效的,选择性 FXR 激动剂,EC50为 4 nM。 | |||
T1394 |
Ibuprofen
Brufen,(±)-Ibuprofe,布洛芬,Motrin,Advil |
COX | Immunology/Inflammation; Neuroscience |
Ibuprofen (Advil) 是一种丙酸衍生物和非甾体抗炎药 (NSAID),具有抗炎、镇痛和解热作用。它是COX-1和COX-2的抑制剂,IC50值分别为 13 和 370 μM,导致前列腺素和血栓素前体的形成减少。 | |||
T0463L |
Loxoprofen sodium
CS-600,CS600,Loxoprofen,CS 600 |
COX | Immunology/Inflammation; Neuroscience |
Loxoprofen sodium (CS-600) 是一种有效的和具有口服活性的非选择性 COX 抑制剂,对 COX-1 和 COX-2具有抑制作用, IC50 分别为 6.5 和 13.5 μM。 Loxoprofen sodium 通过减少花生四烯酸合成前列腺素而起作用。Loxoprofen sodium 具有抗炎和抗肿瘤活性,可用来治疗动脉粥样硬化。 | |||
T0448 |
(S)-(+)-Ibuprofen
左旋布洛芬,Dexibuprofen,(S)-Ibuprofen,(S)-(+)-布洛芬 |
BCL; Thrombin; Cysteine Protease; COX; PPAR | Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience; Proteases/Proteasome |
(S)-(+)-Ibuprofen (Dexibuprofen) 是 Ibuprofen 的 S(+)-对映异构体,能够有效的抑制COX-1(IC50:2.1 μM)和COX-2(IC50:1.6 μM),。它具有抗癌、退热、止痛,抗炎的效果。 | |||
T6498 |
Fenoprofen calcium hydrate
Feprona dihydrate,Fenoprofen calcium salt dihydrate,Progesic dihydrate,非诺洛芬钙二水合物 |
Apoptosis; Others; COX | Apoptosis; Immunology/Inflammation; Neuroscience; Others |
Fenoprofen calcium hydrate (Progesic dihydrate) 是一非甾体类抗炎症化合物。 | |||
T11854 |
Lipofermata
|
Others; Antibacterial | Microbiology/Virology; Others |
Lipofermata 是一种脂肪酸转运蛋白 2抑制剂,可阻止脂质转运至黑色素瘤细胞并减少黑色素瘤的生长和侵袭。 | |||
T15773 |
Lofepramine
Gamanil,洛非帕明,Amplit,Leo 640,Lopramine |
5-HT Receptor; Norepinephrine | GPCR/G Protein; Neuroscience |
Lofepramine (Leo 640) 是一种有效的三环抗抑郁药,广泛地代谢为 Desipramine。它能够抑制摄取促进去甲肾上腺素能神经传递,以及抑制神经元摄取 5-羟色胺和色氨酸吡咯酶,增强 5-羟色胺能神经传递,进而发挥其抗抑郁作用。它还具有显著的抗焦虑效果。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6293 |
Mycophenolate Mofetil
TM-MMF,吗替麦考酚酯,RS 61443 |
Apoptosis; Dehydrogenase; Drug Metabolite | Apoptosis; Metabolism |
Mycophenolate Mofetil (TM-MMF) 是 Mycophenolic acid 的吗啉乙酯前药。它通过抑制肌苷一磷酸脱氢酶抑制从头嘌呤合成,显示出选择性淋巴细胞抗增殖作用。 | |||
T4394 |
Methyl Isoferulate
|
Others | Others |
Methyl Isoferulate 从毛竹叶中分离纯化。 | |||
T0558 |
Dihydroferulic acid
Dihydroconiferylic acid,氢化阿魏酸,Hydroferulic acid |
Others | Others |
Dihydroferulic acid 是一种姜黄素的主要代谢产物,具有抗氧化/清除自由基的活性,其IC50=19.5 μM。它是香草酸的前体物质,也是人类肠道菌群的代谢产物。 | |||
TN1145 |
Isofebrifugine
|
Parasite | Microbiology/Virology |
Isofebrifugine 是一种来自虎耳草科植物常山的生物碱,具有抗疟抗感染活性。 | |||
T2889 |
Isoferulic acid
Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate,异阿魏酸 |
Influenza Virus; Adrenergic Receptor | GPCR/G Protein; Microbiology/Virology; Neuroscience |
Isoferulic acid (Hesperetate) 是一种肉桂酸衍生物,有抗糖尿病活性和抗流感病毒活性。它能结合并激活 α1-肾上腺素能受体,增强 β-内啡肽的分泌并增加体外葡萄糖的使用。 | |||
T9790 |
Lactoferrin
Lactoferrin (Bovine) |
Endogenous Metabolite | Metabolism |
Lactoferrin 由哺乳动物分泌,具有广泛的生物学作用,包括提高应用良好的益生菌菌株的耐寒性。 | |||
T81099 | Staphyloferrin A | ||
Staphyloferrin A,一种铁载体蛋白,与抗生素结合对抗抗药性细菌性皮肤病进行研究。 | |||
TN3662 | Cinnamyl isoferulate | Others | Others |
Cinnamyl isoferulate是一种天然产物,属于杨柳科杨属,其产品编号为 TN3662,CAS号为 115610-31-6。Cinnamyl isoferulate可用作对照参考。 | |||
T40988 | (+)-Norlirioferine | ||
(+)-Norlirioferine is an alkaloid compound that exhibits cell growth inhibitory effects on macrophages and VERO cells. | |||
T10072 |
2-Hydroxy Ibuprofen
2-羟基布洛芬,(±)-2-Hydroxy Ibuprofen |
Others | Others |
2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1/COX-2 (IC50s: 13 μM/370 μM). |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04142 |
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
OPTB7,OFE,OSTS,LOH18CR1,FEO,TRANCER,tumor necrosis ... |
Human | HEK293 |
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. It is an essential mediator for osteoclast and lymph node development. TNFRSF11A and its ligand are important regulators of the interaction between T cells and dendritic cells. It can interact with various TRAF family proteins, through which this recep... | |||
TMPY-05514 |
RANK/TNFRSF11A Protein, Human, Recombinant (mFc)
OFE,RANK,OPTB7,FEO,tumor necrosis factor receptor s... |
Human | HEK293 |
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. It is an essential mediator for osteoclast and lymph node development. TNFRSF11A and its ligand are important regulators of the interaction between T cells and dendritic cells. It can interact with various TRAF family proteins, through which this recep... | |||
TMPY-04157 |
RANK/TNFRSF11A Protein, Human, Recombinant (His)
ODFR,OFE,CD265,PDB2,RANK,tumor necrosis factor rece... |
Human | HEK293 |
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. It is an essential mediator for osteoclast and lymph node development. TNFRSF11A and its ligand are important regulators of the interaction between T cells and dendritic cells. It can interact with various TRAF family proteins, through which this recep... | |||
TMPJ-00349 |
RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)
CD265 antigen,FEO,TRANCER,ODFR,ODFROSTS,TRANCE R,TNFRSF11A,<... |
Human | Human Cells |
Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutive... | |||
TMPY-02728 |
Lactoferrin/LTF Protein, Mouse, Recombinant (His)
MMS10R,Lf,Csp82,lactotransferrin,Ms10r |
Mouse | HEK293 |
Lactotransferrin, also known as Lactoferrin, Talalactoferrin, and LTF, is a secreted protein that belongs to the transferrin family. Transferrins are iron binding transport proteins that can bind two Fe3+ions in association with the binding of an anion, usually bicarbonate. Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Lactoferroxins A, B, and C have opioid antagonist activity. Lactoferrin A shows a preference for mu-receptors, while lactofe... | |||
TMPY-02188 |
Lactoferrin/LTF Protein, Human, Recombinant (His)
HEL110,LF,HLF2,GIG12,lactotransferrin |
Human | HEK293 |
Lactotransferrin, also known as Lactoferrin, Talalactoferrin, and LTF, is a secreted protein that belongs to the transferrin family. Transferrins are iron binding transport proteins that can bind two Fe3+ions in association with the binding of an anion, usually bicarbonate. Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Lactoferroxins A, B, and C have opioid antagonist activity. Lactoferrin A shows a preference for mu-receptors, while lactofe... | |||
TMPH-02646 |
Erythroferrone Protein, Mouse, Recombinant (His)
|
Mouse | Yeast |
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake. | |||
TMPH-01301 |
Erythroferrone Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake. |