Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(R)-baclofen (STX209) 是一种选择性GABAB 受体激动剂。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
5 mg | ¥ 397 | 现货 | ||
10 mg | ¥ 586 | 现货 | ||
50 mg | ¥ 1,890 | 现货 | ||
100 mg | ¥ 2,721 | 现货 | ||
200 mg | ¥ 3,809 | 现货 |
产品描述 | (R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity. |
体外活性 | Baclofen is a skeletal muscle relaxant used in the treatment of spasticity of spinal and cerebral origin. Although it is marketed as a racemic mixture, only the baclofen R-enantiomer is stereospecifically active at so called GAGAB-receptors. [1] Researchers believe that the enantiomers of baclofen have different properties. It is claimed that the R-(?)-enantiomer is about 100 times more active than the S-(+)-enantiomer. |
别名 | STX209, Arbaclofen, (R)-巴氯芬 |
分子量 | 213.66 |
分子式 | C10H12ClNO2 |
CAS No. | 69308-37-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 10 mM
DMSO: Insoluble
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
H2O | 1 mM | 4.6803 mL | 23.4017 mL | 46.8033 mL | 117.0083 mL |
5 mM | 0.9361 mL | 4.6803 mL | 9.3607 mL | 23.4017 mL | |
10 mM | 0.468 mL | 2.3402 mL | 4.6803 mL | 11.7008 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
(R)-baclofen 69308-37-8 Membrane transporter/Ion channel Neuroscience GABA Receptor γ-Aminobutyric acid Receptor inhibit (R)-Baclofen STX 209 STX209 STX-209 Gamma-aminobutyric acid Receptor Arbaclofen (R) baclofen (R)-巴氯芬 baclofen (R)baclofen Inhibitor inhibitor