65
27
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7469 |
Alendronic Acid
alendronate,阿仑膦酸 |
Others | Others |
Alendronic Acid (alendronate) 是法呢基二磷酸合酶(FDPS)抑制剂,是一种双膦酸盐。它能够抑制破骨细胞介导的骨吸收,对绝经后骨质疏松症,恶性高钙血症和 Paget 病具有疗效。 | |||
T21632 |
Myoseverin
|
Others; Microtubule Associated | Cytoskeletal Signaling; Others |
Myoseverina 是多核肌管可逆分裂成单核片段的诱导剂,影响多种生长因子、免疫调节、细胞外基质重塑和应激反应基因的表达,与伤口愈合和组织再生相关通路的激活一致。 | |||
T8575 |
ENFENAMIC ACID
|
Platelet aggregation | Others |
Enfenamic acid 是一种能够抑制伤口愈合的非甾体抗炎药。 | |||
T21653 |
1,4-DPCA
|
HIF/HIF Prolyl-Hydroxylase | Chromatin/Epigenetic; Metabolism |
1,4-DPCA 是一种脯氨酰羟化酶抑制剂,对人源包皮成纤维细胞中胶原羟基化的 IC50 为 2.4 μM,对因子抑制 HIF (FIH) 的 IC50 为 60 μM。 | |||
T16850 |
SB-265610
GSK-CXCR2 |
CXCR | Autophagy; GPCR/G Protein; Immunology/Inflammation |
SB-265610 (GSK-CXCR2) 是竞争性非肽变构CXCR2选择性拮抗剂,可阻断大鼠 CINC-1 诱导的钙动员和中性粒细胞趋化性,IC50分别为 3.7 和 70 nM。 | |||
T4478 |
CID 16020046
C390-0219 |
Cannabinoid Receptor | GPCR/G Protein |
CID 16020046 (C390-0219) 是一种选择性 GPR55 拮抗剂,在酵母中抑制 GPR55 组成型活性,IC50 为 0.15 μM。它抑制 GPR55 介导的 Ca2+信号传导和 GPR55 介导的 ERK1/2 磷酸化,可降低内皮细胞的伤口愈合,参与血小板功能的调节。 | |||
T15259 |
Evatanepag
CP-533536 free acid,2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸 |
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
Evatanepag (CP-533536 free acid) 是一种 EP2 受体选择性前列腺素 E2 (PGE2) 激动剂,可诱导局部骨形成,EC50 为 0.3 nM。它在大鼠骨折愈合模型中以单剂量局部给药时表现出愈合骨折的能力。 | |||
T34685 |
Sonedenoson
MRE-0094,MRE0094,MRE 0094 |
||
Sonedenoson( MRE0094) is an adenosine A2A receptor agonist that promotes rapid wound healing. | |||
T2206 |
Quadrol
N,N,N′,N′-Tetrakis(2-hydroxypropyl)ethylenediamine,EDTP,依的托,Edetol |
Others | Others |
Quadrol (EDTP) 是一种免疫刺激剂,是潜在的能够加速伤口愈合的有用药物。 | |||
T13823 |
Polyvinylpyrrolidone
PVP,Povidone,Polyvidone,聚乙烯吡咯烷酮 |
Others | Others |
Polyvinylpyrrolidone (Polyvidone) 与碘和其他化合物结合后,可用作人类和兽医学中有效的伤口愈合促进剂和消毒剂。 | |||
T19841 |
Tribenoside
Glyvenol,Glyvenal,Ba 2140,BG-356,Glivenol,三苄糖苷,TBGF |
Others | Others |
Tribenoside (BG-356) 是血管保护剂,能够温和的镇痛、抗炎及伤口愈合,可用研究痔疮。 | |||
T35074 |
VRT-325
CFcor 325,VRT-534,CFcor325,VRT 325,VRT325,CF-106951,CFcor-325 |
Others | Others |
VRT-325 可以通过促进两个 NBD 的二聚化或促进 TMD 的折叠来修复折叠缺陷。VRT-325 可加速CF细胞单层的愈合速度。 | |||
T8807 |
Benzydamine
|
Others | Others |
Benzydamine 是一种苄基吲唑,具有镇痛、解热和抗炎作用。 Benzydamine 用于减少手术后和创伤后的疼痛和水肿,并促进愈合。 | |||
T7116 |
Sodium gualenate
Guaiazulenesulfonate sodium,磺酸钠 |
Others | Others |
Sodium gualenate (Guaiazulenesulfonate sodium) 是一种桂皮烯的亲水性衍生物,具有良好的抗炎和愈伤活性,常用于十二指肠溃疡,胃溃疡和胃炎的研究。 | |||
T40570L |
LKKTETQ acetate
LKKTETQ acetate (476014-70-7 Free base) |
Others | Others |
LKKTETQ acetate 是胸腺素 β4 蛋白中的活性位点,负责伤口愈合、肌动蛋白结合和细胞迁移。 | |||
T41206 |
Poly Vinyl Alcohol
Polyvinyl alcohol |
Others | Others |
Poly Vinyl Alcohol (Polyvinyl alcohol)是一种水溶性可生物降解且可用于伤口愈合的聚合物,在生物医学领域广泛使用。Poly Vinyl Alcohol 常用于制作医用辅料。 | |||
TP2319 |
Thymosin β4 acetate(75591-33-4 free base)
|
Autophagy | Autophagy |
Thymosin β4 acetate(75591-33-4 free base) 是一种胸腺激素,具有多种不同的细胞内和细胞外活性,影响伤口愈合、炎症、纤维化和组织再生。 | |||
T74048 |
PAPA NONOate
|
Endogenous Metabolite; NO Synthase | Immunology/Inflammation; Metabolism |
PAPA NONOate 是一种依赖于 pH 调节的 NO 供体。PAPA NONOate 具有潜在的抗肿瘤活性,通过增加伤口部位的胶原合成率,可用于研究糖尿病伤口愈合障碍。 | |||
T31615 |
Elsibucol
AGI-1096,UNII-O7T92N1Y8T,AGI 1096 |
Antioxidant | oxidation-reduction |
Elsibucol (AGI 1096) 是一种VCAM1抑制剂,可用于研究器官移植排斥。Elsibucol 是一种代谢稳定的丙醇衍生物,具有抗氧化、抗炎和抗增殖的特性。它能降低血液中的胆固醇水平,减少受伤动脉中的氧化应激和炎症反应,从而抑制动脉粥样硬化,保护动脉损伤后的内皮愈合。 | |||
T36033 |
DETA NONOate
NOC-18,Diethylamine NONOate |
NO Synthase | Immunology/Inflammation |
DETA NONOate (NOC 18)是外源性一氧化氮 (NO) 供体,具有血管舒张和抗抑郁活性。DETA NONOate 可用于激活神经元中的内向电流,可加速MRSA感染伤口的愈合。 | |||
T21550 |
Blebbistatin
(±)-Blebbistatin |
ATPase; Myosin | Cytoskeletal Signaling; Membrane transporter/Ion channel |
Blebbistatin ((±)-Blebbistatin) 是一种选择性的非肌肉肌球蛋白 II 抑制剂,可促进角膜内皮细胞 (CEC) 的定向迁移并加速伤口愈合,并保留了细胞连接的完整性和屏障功能。 | |||
T32613 |
LCB 03-0110 dihydrochloride
|
Src | Angiogenesis; Tyrosine Kinase/Adaptors |
LCB 03-0110 Dihydrochloride 是BTK 和SYK 家族以及DDR2家族中c-Src 激酶(IC50=1.3 nM)和酪氨酸激酶的有效抑制剂。在体外抑制LPS 诱导的巨噬细胞活化和TGF-β1诱导的成纤维细胞活化,抑制巨噬细胞和成纤维细胞的活化,并抑制伤口愈合模型中的瘢痕形成。 | |||
T31195 |
Dalcotidine
KU 1257,KU-1257 |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Dalcotidine (KU 1257) 是一种新型组胺H2受体拮抗剂,具有组胺H9受体拮抗活性和抗分泌作用,与豚鼠大脑皮层结合的Ki 值为0.040 对分离性豚鼠右心房组胺诱导的正变时反应的拮抗作用的KB 值为0.041。Dalcotidine 提高了溃疡愈合的质量,可能有助于降低溃疡的复发率和复发率。 | |||
T4425 |
JK-P3
|
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
JK-P3 是广谱 VEGFR2抑制剂。它能够抑制 VEGF-A 刺激的 VEGFR2 激活和细胞内信号转导,也可阻碍内皮单层细胞迁移和血管生成,影响成纤维细胞生长因子受体激酶在体外的活性。它具有抗血管生成的作用。 | |||
T41231 |
GP 1a
|
Cannabinoid Receptor; PERK; Arrestin | Apoptosis; GPCR/G Protein |
GP 1a 是cannabinoid receptor 2(CB2)的强效激动剂(EC50=7.1),是在cAMP、GTPγS 和β-arrestin 招募试验中显示的。GP 1a 对CB2受体的选择性约为CB1受体的30倍,且在体外增加HL-60细胞的P-ERK1/2表达。GP 1a 对皮肤伤口愈合有益。GP 1a 可抑制炎症和纤维生成,同时促进上皮的重新形成。 | |||
T33710 |
Nocloprost
|
||
Nocloprost is a prostaglandin E2 analog with local gastroprotective and ulcer-healing activity. | |||
T29547 |
Acemannan
Acemannanan |
||
Acemannan can produce cell proliferation and skin wound healing through AKT/mTOR signaling pathway. | |||
T34087 |
Plaunotol
Kelnac,Plaunotolum |
||
Plaunotol is a gastric protective agent that increases prostaglandins in the gastric mucosa and accelerates ulcer healing. | |||
T34693 |
Sphingosine phosphorylcholine
|
||
Sphingosine phosphorylcholine is a wound healing agent. | |||
T25309 |
Dermabond
Liquid Bandage,2-Octyl 2-cyanoacrylate,RiteLok CON 895 |
||
Dermabond 是一种抗菌化合物,已被用于伤口愈合的基础科学研究。 | |||
T30107 | Apratyramide | ||
Apratyramide is a marine-derived peptidic stimulator of VEGF-A and other growth factors with potential application in wound healing. | |||
T40570 |
LKKTETQ
|
||
LKKTETQ, a peptide segment, is the active site within the protein thymosin β 4 responsible for actin binding, cell migration and wound healing. | |||
T26554 |
Aclerastide
DSC-127,DSC 127,NorLeu-3-A(1-7),DSC127,NorLeu-3A(1-7) |
||
Aclerastide is an angiotensin receptor agonist. Administration of Aclerastide reduced fibrosis and scarring in the healing wounds. This action was more pronounced with longer administration of the peptide after injury. The action of this peptide was block | |||
T28146 |
ND-336
ND336,ND-336 hydrochloride,ND 336 |
||
ND-336 is a highly selective inhibitor ofMMP-2, MMP-9 and MMP-14. ND-336 accelerates diabetic wound healing by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound. | |||
T69755 |
Evatanepag sodium
|
||
Evatanepag, also known as CP-533536, is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation. CP-533536 demonstrated the ability to heal fractures when administered locally as a single dose in rat models of fracture healing. | |||
TP2362 |
Acetyl decapeptide-3
Rejuline,Ac-tyr-arg-ser-arg-lys-tyr-thr-ser-trp-tyr-NH2 |
||
Acetyl decapeptide-3 is a peptide that can stimulate collagen and elastin to increase skin elasticity and increase cell growth and improve healing and repair. | |||
T21185 |
CEP03
CEP 03,CEP-03 |
||
CEP03 enhances EC/EPC proliferation, tubelike formation, and wound-healing efficiency, leading to promote angiogenesis and significantly improve blood flow perfusion recovery in the ischemic hind limbs of mice. | |||
T82358 |
G-{d-Arg}-GDSPASSK
|
||
G-{d-Arg}-GDSPASSK是一种抑制细胞粘附的多肽,有助于促进伤口愈合和组织修复。 | |||
T14139 |
Aganepag
AGN 210937 |
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
Aganepag, a potent Prostanoid EP2 receptor agonist, exhibits remarkable selectivity with an EC50 of 0.19 nM, demonstrating no activity at the EP4 receptor. Its applications are primarily in the fields of wound healing, scar reduction, scar prevention, and the treatment and prevention of wrinkles. | |||
T15642 | KAG-308 | Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
KAG-308 is an effective selective and orally active agonist of the EP4 receptor (Ki: 2.57 nM and EC50: 17 nM for human EP4 receptor), more selective over EP1, EP2, EP3, and IP receptor. KAG-308 suppresses colitis and promotes histological mucosal healing, | |||
T68206 | Arbortristoside A | ||
Arbortristoside A is an anti-inflammatory and antinociceptive. This activity may be due to the inhibiting effect of prostaglandin, histamine and serotonin. Arbortristoside A has also been shown to act on ulcerations and may facilitate healing of peptic ulcers. | |||
T81404 |
Prezatide copper
Bisprezatide copper,PC 1020,Iamin |
||
Prezatide Copper(亦称Iamin)具有促进伤口愈合的多重特性,且用于抑制脱发。 | |||
T71801 |
Arbaprostil
|
||
Arbaprostil is a synthetic prostaglandin E analog that protects gastric mucosa, prevents ulceration, and promotes healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and can inhibit the growth of experimental tumors. Arbaprostil is a prodrug for the potent PGE2. | |||
T41189 |
AY 254
|
||
AY 254 is a potent PAR2 biased agonist. Selectively activates ERK1/2 signaling (EC50= 2 nM for ERK1/2 phosphorylation versus 80 nM for Ca2+release). Reduces cytoKi ne-induced caspase 3/8 activation, promotes scratch-wound healing, and induces IL-8 secretion, in human colorectal cancer (HT29) cellsin vitro. | |||
T34653 | SK1071 | ||
SK1071 is a novel migrastatin analogs, which demonstrated improved performance over migrastatin, with nanomolar IC50 values in chamber cell migration assays with tumor cells and human umbilical vein endothelial cells (HUVECs), and in wound healing assays. | |||
T61106 | GRP78-IN-1 | ||
GRP78-IN-1 displays interactions with specific residues on the GRP78 protein with a binding energy of -8.07 kcal/mol. This compound possesses potent cytotoxic and anti-proliferative effects on cancer cells, particularly demonstrating promising apoptosis in breast cancer cells and wound healing properties [1]. | |||
T70826 | PF-03671148 | ||
PF-03671148 is a potent ALK inhibitor. PF-03671148 inhibits the expression of fibrotic genes and protein markers both in vitro in human fibroblasts and in vivo in a rat wound repair model. Wound healing is not inhibited by the topical application of the ALK5 inhibitor to the wound. PF-03671148 may have potential utility for the prevention of dermal scarring. | |||
T81330 |
Q-Peptide
|
||
Q-Peptide(QHREDGS),是血管生成素-1的衍生肽。在糖尿病小鼠模型中,它通过增加角质形成细胞迁移来改善伤口愈合,并加速伤口闭合。 | |||
T78018 |
Plasminogen
|
||
Plasminogen是一种可由尿激酶血浆蛋白原激活剂(uPA)或组织血浆蛋白原激活剂(tPA)裂解激活的分泌性蛋白,生成血浆蛋白,该酶可以广泛裂解纤维蛋白及其他ECM成分。作为促炎调节剂,Plasminogen能促进急性及糖尿病相关伤口愈合。该蛋白在伤口愈合、炎症和低纤溶酶原血症的研究中有重要应用。 | |||
T75857 |
LL-37, human TFA
|
||
LL-37, human TFA 是一种由37个氨基酸残基组成的两亲性抗菌肽,源自组织蛋白酶,具备广谱抗菌活性。该化合物有助于防护角膜避免感染,同时调节伤口的愈合过程。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3855 |
Tracheloside
|
Estrogen Receptor/ERR; Phosphorylase | Endocrinology/Hormones; Metabolism |
Tracheloside 是抗雌激素木质素,利用 ERK1/2 刺激促进角质形成细胞增殖,是一种良好的促进伤口愈合的药物。 | |||
T3881 |
Vaccarin
|
Integrin; Akt; PERK; AMPK | Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling |
Vaccarin 是从王不留行中提取的一种黄酮糖苷,可显著促进伤口愈合以及伤口部位的内皮和成纤维细胞增殖。它通过激活 AMPK 信号通路改善胰岛素抵抗和脂肪变性。 | |||
T5S1982 |
Periplocin
Periplocoside,杠柳毒苷 |
Apoptosis; Others | Apoptosis; Others |
Periplocin (Periplocoside) 是从黑龙骨中分离出的一种强心类固醇。它可促进肿瘤细胞凋亡并抑制肿瘤生长。它通过激活 Na/K-ATPase 介导的 Src/ERK 和 PI3K/Akt 途径,具有促进伤口愈合的潜力。 | |||
TN1686 |
Ginsenoside Rg4
人参皂苷 RG4 |
Antibacterial | Microbiology/Virology |
Ginsenoside Rg4 是分离自Panax ginsengC. A. Meyer 叶子中的一种人参三醇型人参皂苷。人参三醇型人参皂苷具有多种生物活性,包括防腐,抗糖尿病,伤口愈合,免疫刺激和抗氧化活性等。 | |||
TN3016 |
4',6,7-Trimethoxyisoflavone
|
MMP | Proteases/Proteasome |
4',6,7-Trimethoxyisoflavone 通过 NOX2 诱导促进伤口愈合,从而导致集体迁移和 MMP 活化。 | |||
T2827 |
Asiatic acid
Asiantic acid,Dammarolic acid,积雪草酸 |
Apoptosis; p38 MAPK; Parasite | Apoptosis; MAPK; Microbiology/Virology |
Asiatic acid (Dammarolic acid) 是在Centella asiatica 中发现的一种五环三萜,有抗炎活性,可诱导黑色素瘤细胞的凋亡,有可能治疗皮肤癌。 | |||
TN1079 |
Deoxyelephantopin
|
NF-κB | NF-κB |
Deoxyelephantopin 是来自Elephantopus scaber 的,具有生物活性的天然倍半萜烯内酯,能够抑制NF-κB,MAPK,PI3K/Akt 和β-catenin 信号传导。它可广泛用于癌症方面的研究。 | |||
T1125 |
Shikonin
NSC 252844,Isoarnebin 4,(+)-Shikonin,紫草素,Alkanna Red,C.I. 75535,Anchusa acid |
TNF; NF-κB; Chloride channel; HIV Protease; PKM | Apoptosis; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome |
Shikonin (Anchusa acid) 属于天然产物,是一种 TMEM16A 氯离子通道抑制剂 (IC50=6.5 μM) 和选择性 PKM2 抑制剂。Shikonin 具有抗肿瘤、抗炎和伤口愈合活性。 | |||
TN2077 |
(+/-)-Pinocembrin
NSC 43318,(±)-5,7-Dihydroxyflavanone |
GPR; Others | Endocrinology/Hormones; GPCR/G Protein; Others |
(+/-)-Pinocembrin (NSC-43318) 是一种来自腋松的天然产物,它是一种 GPR120 配体,能促进 HaCaT 细胞系的伤口愈合。 | |||
T13768 |
(+)-Medicarpin
|
Estrogen/progestogen Receptor | Endocrinology/Hormones |
(+)-Medicarpin, a pterocarpan, is an isoflavonoid compound derived from multiple medicinal plant species such as Sophora japonica, Zollernia paraensis, Platymiscium yucatamun, Machaerium aristulatum, and Platymiscium floribundum. It exhibits potent inhibition of osteoclastogenesis and facilitates bone healing and increased bone mass through osteoblast differentiation, which is mediated by the estrogen receptor (ER) β. | |||
T3488 |
Tectorigenin
4',5,7-Trihydroxy-6-methoxyisoflavone,Tectorigenine,鸢尾黄酮,鸢尾黄素 |
Apoptosis | Apoptosis |
Tectorigenin (4',5,7-Trihydroxy-6-methoxyisoflavone) 是一种从葛根汤干燥的花中分离出来的植物异黄酮。 | |||
TN7082 |
demethyldaphnoretin-7-O-glucoside
|
Others | Others |
demethyldaphnoretin-7-O-glucoside 是从 Daphne oleoides Schreber subsp. 中分离出来的天然产物。在土耳其传统医学中,它的地上部分已被用于治疗疟疾、风湿病和伤口愈合。 | |||
TN1132 |
Procyanidin A2
原花青素 A2,原花青素A2 |
IL Receptor; TNF; transporter; Antibacterial | Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology |
Procyanidin A2 是一种具有抗癌、抗氧化、抗菌和抗炎活性的黄酮类天然产物,存在于蔓越莓和越橘中。 | |||
TN1641 | (-)-Fenchone | Others; Antioxidant; Antifungal | Microbiology/Virology; Others; oxidation-reduction |
(-)-Fenchone 是一种双环单萜类化合物,广泛分布于植物中,可从Foeniculum vulgare 和Peumus boldus 中提取。(-)-Fenchone 具有广泛的生物活性,包括抗氧化,伤口愈合,止泻,抗真菌,抗伤害感受和支气管扩张剂活性。(-)-Fenchone 是一种潜在的抗肿瘤化合物。 | |||
T3O2749 |
L-Leucine
(S)-Leucine,Leu,L-亮氨酸,亮氨酸 |
mTOR | PI3K/Akt/mTOR signaling |
L-Leucine ((S)-Leucine) 是必需的支链氨基酸,能够激活 mTOR 信号通路。 | |||
T5S2347 |
Deoxyshikonin
去氧紫草素,Arnebin 7 |
Others; HIF/HIF Prolyl-Hydroxylase; Antibacterial | Chromatin/Epigenetic; Metabolism; Microbiology/Virology; Others |
Deoxyshikonin (Arnebin 7) 是从紫草中分离的天然产物,具有抗肿瘤活性,在体外具有促血管生成作用。它和没食子酸十二烷基酯在体内外均与青霉素有显着的协同抗菌活性。 | |||
TN6926 |
Paeonoside
|
Others | Others |
Paeonoside 发现与P. suffruticosa 中,具有生物活性,可以促进成骨细胞分化过程中的伤口愈合和迁移。Paeonoside 具有一定的抗糖尿病活性,可防止脓毒症和败血症引起的死亡。Paeonoside 对 MC3T3-E1细胞的前成骨细胞没有细胞毒性作用,以剂量依赖性的方式显著恢复伤口区域并促进细胞迁移和促进碱性磷酸酶(ALP)染色及其活性。 | |||
TN6872 |
Trypsin
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Protease-activated Receptor | GPCR/G Protein |
Trypsin 是一种可从鱼类分离出的丝氨酸蛋白酶,可水解赖氨酸或精氨酸羧基侧蛋白质。Trypsin 具有抗炎活性,可通过 PDCoV 的 S 糖蛋白与 pAPN 的相互作用诱导 PDCoV 感染的细胞膜融合,可激活 PAR2 和 PAR4,促进细胞增殖和分化。Trypsin 可用于促进伤口愈合和研究神经源性炎症。 | |||
T1437 |
D-Panthenol
D-泛醇,D-Pantothenyl alcohol,Ilopan,Dexpanthenol,Pantothenol |
Endogenous Metabolite | Metabolism |
D-Panthenol (D-Pantothenyl alcohol) 是 D-pantothenic acid 和胆碱能剂的酒精类似物。D-Panthenol 作为乙酰化反应所必需的辅酶A的前体,参与乙酰胆碱的合成。虽然 D-Panthenol 作用的确切机制尚不清楚,但它可能增强乙酰胆碱的作用。D-Panthenol 作用于胃肠道,增加下肠蠕动。它也适用于局部皮肤,以缓解瘙痒和促进愈合。 | |||
T13559 | Astragaloside VI | EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Astragaloside VI could improve wound healing by activating the EGFR/ERK signaling pathway. | |||
TN6495 | 3,4-O-dimethylcedrusin | ||
3′,4-O-Dimethylcedrusin can improve wound healing in vivo by stimulating the formation of fibroblasts and collagen. | |||
T8001 | Aloe vera | Others | Others |
Aloe vera 是一种天然产品,对伤口特别是皮肤伤口的愈合有很好的作用。 | |||
T40611 |
(E)-Dehydrodiconiferyl alcohol
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(E)-Dehydrodiconiferyl alcohol is a potent dual inhibitor of hCA IX and hCA XII, effectively impeding the catalytic activity of both carbonic anhydrase isoforms. Additionally, (E)-Dehydrodiconiferyl alcohol exerts inhibitory effects on the nuclear translocation of NF-κB in the connective tissue of the healing area. | |||
TN5044 |
Specioside
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Others | Others |
Specioside has antioxidant, analgesic, anti-dyspeptic, astringent, liver stimulating and wound healing activities. It ameliorates oxidative stress and promotes longevity in Caenorhabditis elegans. | |||
T4454 |
Traumatic Acid
Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,愈伤酸,Trans-2-Dodecenedioic Acid |
Antioxidant | oxidation-reduction |
Traumatic Acid (Dodec-2-Enedioic Acid) 是一种单不饱和二元羧酸,从菜豆中分离得到。它可减少膜磷脂的过氧化,并表现出抗氧化和对胶原生物合成的刺激作用。它可用于许多与胶原蛋白生物合成障碍和氧化应激有关的皮肤疾病的研究。 | |||
T81322 |
Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside
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Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside,一种具备伤口愈合活性的化合物,可从Ophioglossum vulgatumL地上部分分离得到。 | |||
T78490 |
Polygalacturonic acid
Galacturonic acid polymer |
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Polygalacturonic acid(Galacturonic acid polymer)为透明胶状物,构成细胞壁关键组分。该酸应用于制备银纳米颗粒(AgNPs),充当抗氧化剂与抗炎剂,防护细胞遭受ROS增高引起的损伤,并促进伤口愈合。Polygalacturonic acid纳米颗粒亦显示抗菌性能。 |