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107

抑制剂 & 化合物

10

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T19644	Benzonatate	Sodium Channel	Membrane transporter/Ion channel
	Benzonatate 是外周口服镇咳药，对咳嗽延伸受体 (cough stretch receptors) 的活性具有抑制作用。它是丁卡因样代谢物，能够阻断呼吸延伸受体的钠通道并产生局部麻醉作用。
T23070	Nisoxetine hydrochloride	Sodium Channel; Monoamine Transporter; Norepinephrine	Membrane transporter/Ion channel; Neuroscience
	Nisoxetine hydrochloride 是一种去甲肾上腺素转运蛋白 (NET) 抑制剂，Kd 值为 0.76 nM。它是抗抑郁药和局部麻药，可以阻断电压门控性钠通道。
T1115	Doxylamine succinate 琥珀酸多西拉敏,Decapryn	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Doxylamine succinate (Decapryn) 是一种吡啶衍生物组胺 H1 拮抗剂，具有明显的镇静特性。它竞争性阻断组胺 H1 受体并限制典型的过敏和过敏反应，可防止组胺引起的皮肤和粘膜疼痛和瘙痒。
T0314	Hexylresorcinol 己雷锁辛,4-己基间苯二酚,4-Hexylresorcinol	Apoptosis; Tyrosinase; Antibacterial; Parasite	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Hexylresorcinol (4-Hexylresorcinol) 是在植物中发现的一种天然产物，具有抗菌、驱虫、防腐和抗肿瘤活性。它是一种可逆、非竞争性的 α-葡萄糖苷酶抑制剂，有抗 DNA 氧化损伤的保护作用。它可诱导鳞癌细胞凋亡。
T0946	Mepivacaine hydrochloride Mepivacaine HCl,盐酸甲哌卡因	Sodium Channel	Membrane transporter/Ion channel
	Mepivacaine hydrochloride (Mepivacaine HCl) 是具有局部麻醉特性的酰胺衍生物。Mepivacaine hydrochloride 与神经元细胞膜上特定的电压门控钠离子通道结合，抑制钠离子内流和膜去极化。
T6953	Prilocaine Citanest,丙胺卡因,Propitocaine,NSC 40027	ATPase; Sodium Channel	Membrane transporter/Ion channel
	Prilocaine (NSC-40027) 是一种氨基酰胺类局部麻醉剂，作用于神经元膜上的钠通道并限制癫痫发作的扩散。它是Na/K-ATPase 抑制剂，具有神经毒性作用。
T0072	Adiphenine hydrochloride Adiphenine HCl,盐酸阿地芬宁,Spasnil,Patrovina,Sentiv	AChR	Neuroscience
	Adiphenine hydrochloride (Patrovina) 是一种烟碱样受体抑制剂，可用作解痉药，对α1、α3β4、α4β2和α4β4的IC50值分别为 1.9、1.8、3.7 和 6.3 µM。
T0916	Butamben Butyl 4-aminobenzoate,4-氨基苯甲酸丁酯	Potassium Channel; Calcium Channel; Sodium Channel	Membrane transporter/Ion channel; Metabolism
	Butamben (Butyl 4-aminobenzoate) 是一种长效局部麻醉剂，用于治疗慢性疼痛。
T0796	Prilocaine hydrochloride Prilocaine HCl,Propitocaine hydrochloride,Xylonest,盐酸丙胺卡因	ATPase; Sodium Channel	Membrane transporter/Ion channel
	Prilocaine hydrochloride (Prilocaine HCl) 是一种氨基酰胺类局部麻醉剂，作用于神经元膜上的钠通道并限制癫痫发作的扩散。它是Na/K-ATPase 抑制剂，具有神经毒性作用。
T0030	Bupivacaine hydrochloride Vivacaine,Bupivacaine HCl,盐酸布比卡因	Sodium Channel	Membrane transporter/Ion channel
	Bupivacaine hydrochloride (Vivacaine) 是NMDA 受体抑制剂，可用于慢性疼痛的研究。它可阻断钠、L-钙和钾通道，还阻断SCN5A 通道，IC50为 69.5 μM。
T13692	Ferric maltol Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate,麦芽酚铁	Others	Others
	Ferric maltol (Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate) 是一种具有口服活性的单一铁离子 (Fe3+) 复合物，可用于研究炎症性肠病缺铁性贫血。
T19869	Elocalcitol Ro 26-9228,BXL 628
	Elocalcitol is a calcitriol analog for inhibition of prostate cell growth.
T124792	Cyclocalopin A
	Cyclocalopin A 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124792。
T0364L	Dibucaine hydrochloride Cinchocaine HCl,Dibucaine HCl,盐酸地布卡因,Cinchocaine hydrochloride	Sodium Channel; AChR	Membrane transporter/Ion channel; Neuroscience
	Dibucaine hydrochloride (Cinchocaine hydrochloride) 是钠通道抑制剂和有效的 SChE 抑制剂。
T2131	Articaine hydrochloride Ultracaine,盐酸阿替卡因,阿替卡因,Articaine HCl,Hoe-045	Sodium Channel	Membrane transporter/Ion channel
	Articaine hydrochloride (Hoe-045) 一种牙科局部麻醉剂。
T0325	Diperodon hydrochloride 盐酸地哌冬,Diothane hydrochloride,Proctodon,Diperocaine	Others	Others
	Diperodon hydrochloride (Diperocaine) 是一种局部麻醉剂，能够被血清分解酶分解，进而产生局部麻醉作用。
T35009	Vadocaine Vadocaina,Vadocainum	Others	Others
	Vadocaine (Vadocaina) 是一种新型的镇咳化合物，可用于局部麻醉，可用于研究中枢神经系统和心血管系统。
T24451	Mepyramine NSC-13136,NSC13136,NSC 13136
	Mepyramine is a histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies both parenterally and locally.
T17115	Tolycaine
	Tolycaine 是一种局部麻醉剂。
T31716L	Etidocaine	Others	Others
	Etidocaine 是一种氨基酸酰胺，用作局部麻醉剂，具有快速起效和长效特性。
T1144L	Lidocaine Hydrochloride hydrate	EGFR; Sodium Channel	Angiogenesis; JAK/STAT signaling; Membrane transporter/Ion channel; Tyrosine Kinase/Adaptors
	Lidocaine Hydrochloride hydrate 是一种酰胺类局部麻醉剂，具有抗炎作用。
T15653	Ketocaine Rec 7-0518	Others	Others
	Ketocaine（Rec 7-0518）是一种动物实验常用的局部麻醉剂，具有潜在的抗肿瘤活性，可用于缓解疼痛。
T28829	Soquinolol Soquinolol mucate	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Soquinolol (Soquinolol mucate) 是一种β肾上腺素能受体拮抗剂，具有较弱的局部麻醉活性。Soquinolol 具有良好的肠内疗效和较长的作用持续时间。
T6443	Chloroprocaine hydrochloride 盐酸氯普鲁卡因,Chloroprocaine HCl	ATPase; Others	Membrane transporter/Ion channel; Others
	Chloroprocaine hydrochloride (Chloroprocaine HCl) 是一种 Na/K-ATPase 活性抑制剂，IC50为 13 mM，可阻断外周神经。
T0364	Dibucaine 地布卡因,Cinchocaine	CaMK; Sodium Channel; AChR	Membrane transporter/Ion channel; Neuroscience
	Dibucaine (Cinchocaine) 是钠通道抑制剂和有效的SChE 抑制剂。
T1526	Nifuratel NF 113,SAP 113,硝呋太尔,Methylmercadone	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Nifuratel (SAP 113) 是广谱抗生素，有抗细菌、真菌和毛滴虫活性。
T27572	Ibuprofen diethylaminoethyl ester Brufen diethylaminoethyl ester,BF-DEAE,BF DEAE	Others	Others
	Ibuprofen diethylaminoethyl ester (BF DEAE) 具有抗炎活性，可作为局部麻醉剂，可用于研究麻风性神经炎等神经系统疾病。
T13995	1-Methyl-7-nitroisatoic anhydride 1M7	Others	Others
	1-Methyl-7-nitroisatoic anhydride (1M7) 是一种能够检测局部核苷酸的试剂。
T68165	Trapencaine
	Trapencaine 是一种新合成的氨基甲酸型局部麻醉剂，诱导的肥大细胞膜上钠通道的构象变化。
T1389	Dyclonine hydrochloride 盐酸达克罗宁,Dyclocaine hydrochloride,Dyclonine HCl	Sodium Channel; Antibacterial; Antifungal	Membrane transporter/Ion channel; Microbiology/Virology
	Dyclonine hydrochloride (Dyclonine HCl) 是润喉片的有效成分，具有显著的杀菌和杀真菌作用。
T6566	Levobupivacaine hydrochloride Levobupivacaine HCl,(S)-(-)-Bupivacaine HCl,盐酸左布比卡因,(S)-(-)-Bupivacaine monohydrochloride	Sodium Channel	Membrane transporter/Ion channel
	Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) 是有效的钠通道阻滞剂。
T7118	Dimethocaine 二甲卡因,Larocaine	Others; Dopamine Receptor	GPCR/G Protein; Neuroscience; Others
	Dimethocaine (Larocaine) 是一种局部麻醉剂，也对中枢神经系统起多巴胺再摄取抑制剂的作用。
T0378	Oxybuprocaine hydrochloride Risedronic Acid,Oxybuprocaine HCl,奥布卡因盐酸盐	Sodium Channel	Membrane transporter/Ion channel
	Oxybuprocaine hydrochloride (Oxybuprocaine HCl) 是可逆的钠通道阻断剂，可防止角膜，结膜和巩膜中疼痛神经的冲动传播。Oxybuprocaine hydrochloride 专用于眼科与耳鼻喉科。
T21444	Diphenylcyclopropenone DPCP,Diphencyprone,二苯基环丙烯酮	Others	Others
	Diphenylcyclopropenone (DPCP) 是局部免疫调节剂，可用于研究斑秃。
T0328	Hexetidine NSC-17764,海克替啶	Antibacterial; Antifungal	Microbiology/Virology
	Hexetidine (NSC-17764) 是一种口服活性的抗菌抗真菌试剂，可用于口腔感染的相关研究。
T14038L	4-Azido-L-phenylalanine hydrochloride p-Azido-L-phenylalanine hydrochloride,p-Azidophenylalanine hydrochloride	Others	Others
	4-Azido-L-phenylalanine hydrochloride (p-Azido-L-phenylalanine hydrochloride) 是非天然氨基酸，可有效振动报道蛋白质环境。
T0726	Benzydamine hydrochloride Benzydamine HCl,盐酸苄达明,AF864	COX; PGE Synthase; Antibacterial	Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Benzydamine hydrochloride (AF864) 是一种局部作用的非甾体抗炎药，具有局部麻醉和镇痛作用。它也是前列腺素合成酶抑制剂，有抗细菌活性。
T1198	Tetracaine hydrochloride 盐酸丁卡因,Amethocaine hydrochloride,Amethocalne HCl,Tetracaine HCl	Calcium Channel; Sodium Channel	Membrane transporter/Ion channel; Metabolism
	Tetracaine hydrochloride (Amethocalne HCl) 是一种钙通道蛋白抑制剂，可阻断肌浆网中 Ca2+的电压敏感释放。它主要用作眼科的止痒剂和局部用药，可用于表面和脊髓麻醉。
T0386	Ropivacaine hydrochloride 盐酸罗哌卡因,Ropivacaine monohydrochloride	Potassium Channel; Sodium Channel	Membrane transporter/Ion channel
	Ropivacaine hydrochloride (Ropivacaine monohydrochloride) 是钠通道阻断剂，通过可逆地抑制钠离子内流从而引起神经纤维脉冲传导阻滞。Ropivacaine hydrochloride 也是 K2P(双孔钾通道)TREK-1的抑制剂。在动物实验模型中，Ropivacaine hydrochloride 可用于神经性疼痛的缓解。
T1787	Levobupivacaine	Sodium Channel	Membrane transporter/Ion channel
	Levobupivacaine 是一种氨基酰胺类局麻药，属于n-alkylsubstituted pipecoloxylidide 家族。它是bupivacaine 的 S-对映异构体。
T27397	Gacyclidine GK 11,OTO311,OTO-311,OTO 311,GK-11	NMDAR	Neuroscience
	Gacyclidine (OTO311) 是一种小分子 N-甲基-D-天冬氨酸(NMDA)受体拮抗剂。在耳蜗局部注射加西环定可抑制水杨酸盐引起的耳鸣，可用于治疗脑损伤、脊髓损伤和耳鸣。
T0386L	Ropivacaine LEA-103 HCl,罗哌卡因	Potassium Channel; Sodium Channel	Membrane transporter/Ion channel
	Ropivacaine (LEA-103 HCl) 是有效的钠通道阻断剂，通过可逆地抑制钠离子内流从而引起神经纤维脉冲传导阻滞。Ropivacaine 也是一种 K2P(双孔钾通道)TREK-1的抑制剂，在 COS-7 细胞膜上的 IC50值为 402.7 μM。Ropivacaine 可以用于神经性疼痛的缓解的相关研究。
TP1820L	Osteogenic Growth Peptide, OGP acetate Osteogenic Growth Peptide, OGP acetate(132996-61-3 free base)	Others	Others
	Osteogenic Growth Peptide, OGP acetate(132996-61-3 free base) 是一种短的、天然存在的 14 聚体生长因子肽，存在于血清中，浓度为 μM。成骨生长肽 OGP 是局部骨髓损伤全身成骨反应机制的关键因素。
T34383L	2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv	Others	Others
	2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv在Sprague Dawley大鼠上进行测试时显示出高局部抗炎效力和高肺选择性。
T0901	Chlorobutanol Chlortran,Chloretone,YM-57158,三氯叔丁醇,Chlorbutol,Chloreton	Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Chlorobutanol (Chlortran) 是一种药物防腐剂，对多种革兰氏阳性和革兰氏阴性细菌以及几种霉菌孢子和真菌具有抗性。它广泛用于食品和化妆品工业，有促进安定、睡眠的作用。
T15259	Evatanepag CP-533536 free acid,2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Evatanepag (CP-533536 free acid) 是一种 EP2 受体选择性前列腺素 E2 (PGE2) 激动剂，可诱导局部骨形成，EC50 为 0.3 nM。它在大鼠骨折愈合模型中以单剂量局部给药时表现出愈合骨折的能力。
T22361	Mepivacaine Carbocaine	Sodium Channel	Membrane transporter/Ion channel
	Mepivacaine (Carbocaine) 是一种可用于局部麻醉的酰胺类化合物，可使人或动物短暂的失去自知觉。Mepivacaine 通过与神经细胞膜上特定的电压门控钠离子通道结合，抑制钠离子内流和膜去极化来发挥作用。Mepivacaine 适用于神经阻滞和硬膜外麻醉。
T1144	Lidocaine hydrochloride Lidocaine HCL,盐酸利多卡因,Lignocaine hydrochloride,Xyloneural,Lidothesin	Apoptosis; ERK; NF-κB; MEK; Sodium Channel	Apoptosis; MAPK; Membrane transporter/Ion channel; NF-κB
	Lidocaine hydrochloride (Lignocaine hydrochloride) 抑制涉及复杂电压和依赖性的钠通道。它通过调节 miR-145 表达和进一步抑制 MEK/ERK 和 NF-κB 信号通路来减少胃癌细胞的生长，迁移和侵袭。Lidocaine 是一种酰胺衍生物，是一种研究室性心律失常的药物和有效的肿瘤抑制剂。
T0802	Procaine hydrochloride Novocaine HCl,Procaine HCl,盐酸普鲁卡因	Histone Demethylase; 5-HT Receptor; DNA/RNA Synthesis; Sodium Channel; NMDAR; AChR	Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	Procaine hydrochloride (Novocaine HCl) 是DNA 脱甲基剂，是一种苯甲酸衍生物，具有局部麻醉和抗心律失常特性。
T0468	Lidocaine Lignocaine,Alphacaine,Xylocaine,利多卡因	Apoptosis; ERK; NF-κB; MEK; Sodium Channel; Histamine Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; MAPK; Membrane transporter/Ion channel; Neuroscience; NF-κB
	Lidocaine (Alphacaine) 是一种酰胺衍生物，抑制涉及复杂电压和依赖性的钠通道，可用于研究室性心律失常。它通过调节 miR-145 表达和进一步抑制 MEK/ERK 和 NF-κB 信号通路来减少胃癌细胞的生长，迁移和侵袭。

化合物

Cat.No: T19644

Target: Sodium Channel

Nisoxetine hydrochloride

Cat.No: T23070

Target: Sodium Channel, Monoamine Transporter, Norepinephrine

Doxylamine succinate

Cat.No: T1115

Synonym: 琥珀酸多西拉敏,Decapryn

Target: Histamine Receptor

Hexylresorcinol

Cat.No: T0314

Synonym: 己雷锁辛,4-己基间苯二酚,4-Hexylresorcinol

Target: Apoptosis, Tyrosinase, Antibacterial, Parasite

Mepivacaine hydrochloride

Cat.No: T0946

Synonym: Mepivacaine HCl,盐酸甲哌卡因

Target: Sodium Channel

Cat.No: T6953

Synonym: Citanest,丙胺卡因,Propitocaine,NSC 40027

Target: ATPase, Sodium Channel

Adiphenine hydrochloride

Cat.No: T0072

Synonym: Adiphenine HCl,盐酸阿地芬宁,Spasnil,Patrovina,Sentiv

Target: AChR

Cat.No: T0916

Synonym: Butyl 4-aminobenzoate,4-氨基苯甲酸丁酯

Target: Potassium Channel, Calcium Channel, Sodium Channel

Prilocaine hydrochloride

Cat.No: T0796

Synonym: Prilocaine HCl,Propitocaine hydrochloride,Xylonest,盐酸丙胺卡因

Target: ATPase, Sodium Channel

Bupivacaine hydrochloride

Cat.No: T0030

Synonym: Vivacaine,Bupivacaine HCl,盐酸布比卡因

Target: Sodium Channel

Cat.No: T13692

Synonym: Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate,麦芽酚铁

Target: Others

Cat.No: T19869

Synonym: Ro 26-9228,BXL 628

Cat.No: T124792

Dibucaine hydrochloride

Cat.No: T0364L

Synonym: Cinchocaine HCl,Dibucaine HCl,盐酸地布卡因,Cinchocaine hydrochloride

Target: Sodium Channel, AChR

Articaine hydrochloride

Cat.No: T2131

Synonym: Ultracaine,盐酸阿替卡因,阿替卡因,Articaine HCl,Hoe-045

Target: Sodium Channel

Diperodon hydrochloride

Cat.No: T0325

Synonym: 盐酸地哌冬,Diothane hydrochloride,Proctodon,Diperocaine

Target: Others

Cat.No: T35009

Synonym: Vadocaina,Vadocainum

Target: Others

Cat.No: T24451

Synonym: NSC-13136,NSC13136,NSC 13136

Cat.No: T17115

Cat.No: T31716L

Target: Others

Lidocaine Hydrochloride hydrate

Cat.No: T1144L

Target: EGFR, Sodium Channel

Cat.No: T15653

Synonym: Rec 7-0518

Target: Others

Cat.No: T28829

Synonym: Soquinolol mucate

Target: Adrenergic Receptor

Chloroprocaine hydrochloride

Cat.No: T6443

Synonym: 盐酸氯普鲁卡因,Chloroprocaine HCl

Target: ATPase, Others

Cat.No: T0364

Synonym: 地布卡因,Cinchocaine

Target: CaMK, Sodium Channel, AChR

Cat.No: T1526

Synonym: NF 113,SAP 113,硝呋太尔,Methylmercadone

Target: Antibacterial, Antibiotic, Parasite

Ibuprofen diethylaminoethyl ester

Cat.No: T27572

Synonym: Brufen diethylaminoethyl ester,BF-DEAE,BF DEAE

Target: Others

1-Methyl-7-nitroisatoic anhydride

Cat.No: T13995

Synonym: 1M7

Target: Others

Cat.No: T68165

Dyclonine hydrochloride

Cat.No: T1389

Synonym: 盐酸达克罗宁,Dyclocaine hydrochloride,Dyclonine HCl

Target: Sodium Channel, Antibacterial, Antifungal

Levobupivacaine hydrochloride

Cat.No: T6566

Synonym: Levobupivacaine HCl,(S)-(-)-Bupivacaine HCl,盐酸左布比卡因,(S)-(-)-Bupivacaine monohydrochloride

Target: Sodium Channel

Cat.No: T7118

Synonym: 二甲卡因,Larocaine

Target: Others, Dopamine Receptor

Oxybuprocaine hydrochloride

Cat.No: T0378

Synonym: Risedronic Acid,Oxybuprocaine HCl,奥布卡因盐酸盐

Target: Sodium Channel

Diphenylcyclopropenone

Cat.No: T21444

Synonym: DPCP,Diphencyprone,二苯基环丙烯酮

Target: Others

Cat.No: T0328

Synonym: NSC-17764,海克替啶

Target: Antibacterial, Antifungal

4-Azido-L-phenylalanine hydrochloride

Cat.No: T14038L

Synonym: p-Azido-L-phenylalanine hydrochloride,p-Azidophenylalanine hydrochloride

Target: Others

Benzydamine hydrochloride

Cat.No: T0726

Synonym: Benzydamine HCl,盐酸苄达明,AF864

Target: COX, PGE Synthase, Antibacterial

Tetracaine hydrochloride

Cat.No: T1198

Synonym: 盐酸丁卡因,Amethocaine hydrochloride,Amethocalne HCl,Tetracaine HCl

Target: Calcium Channel, Sodium Channel

Ropivacaine hydrochloride

Cat.No: T0386

Synonym: 盐酸罗哌卡因,Ropivacaine monohydrochloride

Target: Potassium Channel, Sodium Channel

Levobupivacaine

Cat.No: T1787

Target: Sodium Channel

Cat.No: T27397

Synonym: GK 11,OTO311,OTO-311,OTO 311,GK-11

Target: NMDAR

Cat.No: T0386L

Synonym: LEA-103 HCl,罗哌卡因

Target: Potassium Channel, Sodium Channel

Osteogenic Growth Peptide, OGP acetate

Cat.No: TP1820L

Synonym: Osteogenic Growth Peptide, OGP acetate(132996-61-3 free base)

Target: Others

2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv

Cat.No: T34383L

Target: Others

Cat.No: T0901

Synonym: Chlortran,Chloretone,YM-57158,三氯叔丁醇,Chlorbutol,Chloreton

Target: Antibacterial, Antibiotic, Antifungal

Cat.No: T15259

Synonym: CP-533536 free acid,2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸

Target: Prostaglandin Receptor

Cat.No: T22361

Synonym: Carbocaine

Target: Sodium Channel

Lidocaine hydrochloride

Cat.No: T1144

Synonym: Lidocaine HCL,盐酸利多卡因,Lignocaine hydrochloride,Xyloneural,Lidothesin

Target: Apoptosis, ERK, NF-κB, MEK, Sodium Channel

Procaine hydrochloride

Cat.No: T0802

Synonym: Novocaine HCl,Procaine HCl,盐酸普鲁卡因

Target: Histone Demethylase, 5-HT Receptor, DNA/RNA Synthesis, Sodium Channel, NMDAR, AChR

Cat.No: T0468

Synonym: Lignocaine,Alphacaine,Xylocaine,利多卡因

Target: Apoptosis, ERK, NF-κB, MEK, Sodium Channel, Histamine Receptor

Cat. No.	Product Name	Target	Signaling Pathways
TN4684	O-Acetylcyclocalopin A	Others	Others
	O-Acetylcyclocalopin A是一种天然产物，其产品编号为 TN4684，CAS号为 486430-93-7。O-Acetylcyclocalopin A可用作对照参考。
T0012	Cinchonine LA40221,(8R,9S)-Cinchonine,奎宁树,辛可宁	Apoptosis; P-gp; Parasite	Apoptosis; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	Cinchonine (LA40221) 是金鸡纳树皮中的一种天然产物。它可激活内质网应激诱导的人肝癌细胞凋亡。它是一种酰胺类局部麻醉剂。
T1407	(-)-Menthol L-Menthol,Levomenthol,(-)-薄荷醇,薄荷冰,Menthomenthol,Menthacamphor	Opioid Receptor; Endogenous Metabolite; TRP/TRPV Channel	Endocrinology/Hormones; GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience
	(-)-Menthol (Levomenthol) 分离自薄荷油，L-Menthol 是瞬时受体电位 M8 (TRPM8)的激活剂，TRPM8 是 Ca2+-可渗透的非选择性阳离子通道，并增加 [Ca2+]i。L-Menthol 具有抗肿瘤活性。
T5S1550	Cinnamyl alcohol 肉桂醇,肉桂醇；beta-苯丙烯醇,Cinnamic Alcohol,Styryl Carbinol	PPAR	DNA Damage/DNA Repair; Metabolism
	Cinnamyl alcohol (Styryl Carbinol) 是从板栗花中分离得到的一种活性成分，抑制增加的 PPARγ表达，具有抗肥胖作用。
T5723	Menthol 薄荷脑,DL-Menthol	Others; Calcium Channel	Membrane transporter/Ion channel; Metabolism; Others
	Menthol (DL-Menthol) 是从薄荷或薄荷油中得到的一种天然产物，具有调味和局部麻醉特性。它通过抑制神经元细胞膜的 Ca++电流，刺激冷感受器，从而产生清凉的感觉。
T1301	Guaiacol O-methylcatechol,2-hydroxyanisole,o-methoxyphenol,2-Methoxyphenol,愈创木酚	NF-κB; COX; Endogenous Metabolite	Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	Guaiacol (2-Methoxyphenol) 是从小叶栲中提取的一种酚类，可抑制 LPS 刺激的COX-2表达和NF-κB 激活，具有抗炎活性。
T3893	Forsythoside B 连翘酯苷 B,连翘脂苷B	TNF; NF-κB	Apoptosis; NF-κB
	Forsythoside B 是传统中药植物独一味叶子中分离的一种苯乙醇苷。它可抑制 TNF-alpha，IL-6，IκB，调节 NF-κB。它抑制炎症反应，具有抗氧化和神经保护作用。
TN6028	Gardneramine
	Gardneramine has a mild central depressive effect. Gardneramine and hirsutine show a local anesthetic action, they also can inhibit the ganglionic transmission of the dog urinary bladder and that the blockade of the nicotinic receptor plays a main role.
T35770	Cylindrospermopsin
	Cylindrospermopsin, a tricyclic uracil derivative, is a cyanobacterial toxin that was first discovered in an algal bloom contaminating a local drinking supply on Palm Island in Queensland, Australia after an outbreak of a mysterious disease. Cylindrospermopsin targets protein and glutathione synthesis in hepatocytes (IC50s = 1.3 and 2.4 &#181M, respectively), leading to cell death. [1] It has been shown to inhibit the activity of the uridine monophosphate synthase complex with a Ki value of 10 &...
T36489	Malformin A
	Malformin A is a cyclopentapeptide fungal metabolite that has been found in A. niger and has diverse biological activities. It is a plant growth regulator that induces malformations in plant structure. Malformin A inhibits replication of tobacco mosaic virus (TMV) in local lesion and leaf-disc assays (IC50s = 19.7 and 45.4 μg/ml, respectively). It is cytotoxic to NCI-H460, MIA PaCa-2, MCF-7, SF-268, and WI-38 cancer cells (IC50s = 70, 50, 100, 70, and 100 nM, respectively), inhibits proliferati...

天然产物

O-Acetylcyclocalopin A

Cat.No: TN4684

Target: Others

Cat.No: T0012

Synonym: LA40221,(8R,9S)-Cinchonine,奎宁树,辛可宁

Target: Apoptosis, P-gp, Parasite

Cat.No: T1407

Synonym: L-Menthol,Levomenthol,(-)-薄荷醇,薄荷冰,Menthomenthol,Menthacamphor

Target: Opioid Receptor, Endogenous Metabolite, TRP/TRPV Channel

Cinnamyl alcohol

Cat.No: T5S1550

Synonym: 肉桂醇,肉桂醇；beta-苯丙烯醇,Cinnamic Alcohol,Styryl Carbinol

Target: PPAR

Cat.No: T5723

Synonym: 薄荷脑,DL-Menthol

Target: Others, Calcium Channel

Cat.No: T1301

Synonym: O-methylcatechol,2-hydroxyanisole,o-methoxyphenol,2-Methoxyphenol,愈创木酚

Target: NF-κB, COX, Endogenous Metabolite

Cat.No: T3893

Synonym: 连翘酯苷 B,连翘脂苷B

Target: TNF, NF-κB

Cat.No: TN6028

Cylindrospermopsin

Cat.No: T35770

Cat.No: T36489

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