180
20
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T20913 |
Light Green SF Yellowish
Acid Green 5,C.I. Acid Green 5,C.I. 42095 |
||
Light Green SF Yellowish (Acid Green 5) 是一种碱性染色剂,可用于动物组织染色,可用于植物组织学中作细胞质和纤维染色。 | |||
T22865 |
immunoglobulin light chain variable region fragment [Homo sapiens]
|
Others | Others |
Immunoglobulin light chain variable region fragment [Homo sapiens] is a fragment (Phe-Thr-Leu-Lys-Ile-Ser-Arg) on the variable region of the human immunoglobulin light chain. | |||
TP2259 |
immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]
|
Others | Others |
Immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus] is a fragment on the variable region of the human and mouse immunoglobulin light chain. Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule | |||
T22856 |
IgG light chain variable region [Homo sapiens]/IgM/kappa antibody [Mus musculus]
|
Others | Others |
IgG has four forms, provides the majority of antibody-based immunity against invading pathogens. The only antibody capable of crossing the placenta to give passive immunity to the fetus. Eliminates pathogens in the early stages of B cell-mediated (humoral | |||
T6617 |
Optovin
|
TRP/TRPV Channel | Membrane transporter/Ion channel |
Optovin 是可逆的光活化 TRPA1配体,可实现光介导的神经元兴奋。它通过与氧化还原敏感的半胱氨酸残基产生结构依赖性光化学反应激活 TRPA1。 | |||
T81732 |
Myosin light chain kinase fragment 11-19 amide
MLCK(11-19) amide |
||
Myosinlight chain kinase fragment 11-19 amide (MLCK(11-19) amide) 为MLCK专一性多肽抑制剂,具抑制低渗透压刺激下Ca2+入细胞的能力,并可应用于人类宫颈癌研究。 | |||
T0343 |
Nimodipine
尼莫地平,BAY-e 9736 |
Glucocorticoid Receptor; AhR; Calcium Channel; Autophagy | Autophagy; Endocrinology/Hormones; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism |
Nimodipine (BAY-e 9736) 是一种具有口服活性,耐受性良好的光敏二氢吡啶钙拮抗剂。它可研究脑血管疾病。 | |||
T3213 |
Hematoporphyrin dihydrochloride
血卟啉二盐酸盐,Hematoporphyrin IX dihydrochloride |
Apoptosis; Others; Endogenous Metabolite | Apoptosis; Metabolism; Others |
Hematoporphyrin dihydrochloride (Hematoporphyrin IX dihydrochloride) 是一种光敏剂,是血红素结合蛋白亲和色谱底物。它暴露在红光下时,可诱导 U87 胶质瘤细胞凋亡,并降低体内肿瘤的生长。 | |||
T21343 |
PTZ-343
PTZ-343 sodium,PTZ 343,吩噻嗪-10-基-丙基磺酸钠盐 |
Others | Others |
PTZ-343 是一种鲁米诺的强效发光增强剂 (enhancer)。它极大的增强了过氧化物酶催化的鲁米诺化学发光氧化反应 (>80%) 的光输出。 | |||
T20792 |
W-7 hydrochloride
N-(6-氨基己基)-5-氯-1-萘磺胺盐酸盐,W 7 HCl,W7 HCl,W-7 HCl |
CaMK; Apoptosis; Myosin; PDE | Apoptosis; Cytoskeletal Signaling; Metabolism; Neuroscience |
W-7 hydrochloride (W-7 HCl) 是一种选择性的钙调蛋白拮抗剂。它抑制Ca2+-钙调蛋白依赖性磷酸二酯酶和肌球蛋白轻链激酶,IC50值分别为 28 μM 和 51 μM。它可诱导细胞凋亡,具有抗癌活性。 | |||
T0642 |
2-Methoxyphenothiazine
|
Factor Xa | Metabolism |
2-Methoxyphenothiazine 为淡黄色或淡灰色固体。 | |||
T77752 |
HMBR
4-Thiazolidinone, 5-[(4-hydroxy-3-methylphenyl)methylene]-2-thioxo-, (5Z)- |
Others | Others |
HMBR本身不具有荧光,但当与 Y-FAST 结合时,它们在蓝光激发时会发出黄光。 | |||
T0659 |
Bispyrazolone
NSC 37393,依达拉奉杂质IV |
Others | Others |
Bispyrazolone (NSC-37393) 为淡黄色或白色结晶性粉末。 | |||
T9550 |
Drometrizole Trisiloxane
甲酚曲唑三硅氧烷,Mexoryl XL,Silatrizole |
Others | Others |
Drometrizole Trisiloxane (Mexoryl XL) 是一种光稳定的 UVA 和 UVB 滤光剂。 | |||
T24533 |
Nicotinoyl azide
N-Az,NAz,叠氮烟酸甲酰,N Az |
Others | Others |
Nicotinoyl azide (N-Az) 是一种光活化化学探针。它已被用于测量嘌呤核碱基的溶剂可及性。 | |||
T3050 |
ML-7 hydrochloride
ML-7 HCl,ML-7盐酸盐 |
Serine/threonin kinase; Myosin; YAP; PKA; PKC | Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Stem Cells; Tyrosine Kinase/Adaptors |
ML-7 hydrochloride (ML-7 HCl) 是一种可渗透细胞的、可逆的、有效的、ATP 竞争性的肌球蛋白轻链激酶(MLCK) 特异性抑制剂,IC50为300 nM。它还抑制平滑肌肌球蛋白轻链激酶、PKA 和 PKC。 | |||
T26078 |
Rhodblock 6
Rhodblock6,Rhodblock-6 |
ROCK | Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells |
Rhodblock 6 是一种 Rho 激酶 (ROCK) 抑制剂,可抑制磷酸化 MRLC(肌球蛋白调节轻链)定位,通过特异性抑制 Rho 激酶的活性发挥作用。 | |||
T40684 |
N-Nitrosomorpholine
|
Others | Others |
N-Nitrosomorpholine 是一种亚硝胺,具有光敏感性。它对动物有强致癌作用。 | |||
T1699 |
resorufin galactopyranoside
|
Others | Others |
resorufin galactopyranoside 是β-半乳糖苷酶的荧光底物,在被β-半乳糖苷酶酶切后,荧光部分间苯二酚被释放,其荧光可用于定量β-半乳糖糖苷酶的活性。它的激发光为570,发射光为580nm。 | |||
T21282 |
Topanol CA
|
Others | Others |
Topanol CA 是一种抗氧化剂,可用于树脂和浅色橡胶制品中作稳定剂。 | |||
T27931 |
LY2033298
LY 2033298,LY-2033298 |
AChR | Neuroscience |
LY2033298 是毒蕈碱 M4 受体的正变构调节剂,可增强奥昔莫林对仓鼠昼夜节律活动中光诱导的相移的抑制作用,可用于与神经系统相关的疾病。 | |||
T0691 |
Sulisobenzone
舒利苯酮,Benzophenone-4,Sungard |
Others | Others |
Sulisobenzone (Sungard) 是防晒霜的成分,能够保护皮肤,使其免于受UVB 和短波紫外线UVA 的伤害。 | |||
T35501 |
5,6-trans-Vitamin D3
5,6-trans-Colecalciferol,5,6-trans-Cholecalciferol,Cholecalciferol EP Impurity A |
Vitamin | Metabolism |
5,6-trans-Vitamin D3(5,6-trans-Cholecalciferol)是维生素 D3 的异构体,经光照后在皮肤表面由 Vitamin D3 转化而来。 | |||
T14994 |
Coelenterazine h
腔肠素-H,2-Deoxycoelenterazine,CLZN-h |
Others | Others |
Coelenterazine h (CLZN-h) 是一种 Coelenterazine 的衍生物。它对 Ca2+比它的天然复合物更敏感,是一种能够测量 Ca2+浓度的微小变化的有效工具。 | |||
T7465 |
4-Methylbenzylidene camphor
Enzacamene,4-甲基苄亚基樟脑,3-(4-甲基苯亚甲基)樟脑,4-MBC |
AChE | Neuroscience |
4-Methylbenzylidene camphor 是有机的樟脑衍生物,应用于化妆品行业,具有保护皮肤抵抗紫外线(特别是紫外线B 辐射)的能力。 | |||
T19743 |
D-Luciferin Sodium
D-萤光素钠盐,D-虫荧光素钠 |
Others | Others |
D-Luciferin sodium 是一种萤光素酶底物,能够催化生物发光昆虫产生典型的黄绿光。 | |||
T83633 |
1-N-Methyl-4-mercaptohistidine disulfide
|
Others | Others |
1-N-Methyl-4-mercaptohistidine disulfide 是一种潜在的杜氏菌叶绿体偶联因子1氧化还原调节剂,是氧化形式的卵硫醇A,抑制光触发的CF1 ATP酶活性。 | |||
T8940 |
KUN56321
3H-Naphth[1,2-d]imidazole, 2-(4-bromophenyl)-3-phenyl- |
Others | Others |
KUN56321 (3H-Naphth[1,2-d]imidazole, 2-(4-bromophenyl)-3-phenyl-) 是一种发光剂。 KUN56321的应用包括:真空蒸镀将 KUN56321薄膜涂布在 ITO 玻璃的空穴传输层或电子传输层上。将空穴传输层或电子传输层蒸镀在薄膜上,preppg。蒸发金属电极。 KUN56321 展示了提高发光效率和降低 org 驱动电压的能力。发光器件和显示器件。 | |||
TP1890L1 |
MLCK inhibitor peptide 18 acetate
MLCK inhibitor peptide 18 acetate(224579-74-2 free base) |
Serine/threonin kinase | Cell Cycle/Checkpoint; Metabolism |
MLCK inhibitor peptide 18 acetate(224579-74-2 free base) 是肌球蛋白轻链激酶的选择性竞争性抑制剂 (IC50 = 50 nM)。显示出比 CaM 激酶 II 高 4000 倍的选择性,并且不抑制 PKA。细胞可渗透。 | |||
T67886 |
Girard's Reagent T
Trimethylacetohydrazideammonium Chloride |
Others | Others |
Girard's Reagent T (Trimethylacetohydrazideammonium Chloride) 是生化试剂。Girard's Reagent T 在温和的酸性或碱性条件下,与含有α-二羰基官能团的醛类和酮类反应,生成强吸收紫外线的加成化合物 | |||
T16562 |
Ponceau 4R
Acid Red 18,New Coccine |
Others | Others |
Ponceau 4R (Acid Red 18) 是一种合成草莓红偶氮染料,是一种可用为食品着色剂染料,可用于各种食品。它对光、热和酸都很稳定,但在抗坏血酸存在下会褪色。它通常由芳香烃合成。 | |||
T16104 |
ML-9
|
Myosin; Akt | Cytoskeletal Signaling; PI3K/Akt/mTOR signaling |
ML-9 是 Akt 激酶的一种选择性强效抑制剂,可抑制肌球蛋白轻链激酶 (MLCK) 和基质相互作用分子1(STIM1) 活性。它通过刺激自噬小体的形成并抑制其降解来诱导自噬。它抑制 MLCK,PKA 和 PKC 活性,Ki 值分别为 4、32 和 54 μM。 | |||
T1433 |
Ritodrine hydrochloride
DU21220,盐酸利托君,Ritodrine HCl,NSC 291565 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Ritodrine hydrochloride (NSC 291565) 是一种 β-2肾上腺素受体激动剂。 | |||
T0075 |
Nicorandil
SG-75,尼可地尔 |
Potassium Channel | Membrane transporter/Ion channel |
Nicorandil (SG-75) 是一种有效的钾通道激活剂,靶向血管核苷二磷酸依赖性 K+通道和心脏 ATP 敏感 K+通道 (KATP)。Nicorandil 是一种烟酰胺酯,具有血管舒张和心脏保护作用,并具有治疗心绞痛和缺血性心脏病的潜力。 | |||
T9403 |
1,3,5-tris(pyridin-4-ylethynyl)benzene
|
Others | Others |
1,3,5-tris(pyridin-4-ylethynyl)benzene 是一种杂环化合物,具有广泛的性质,如荧光和电化学活性,具有相对较低的毒性。它已被用作合成各种材料的构建块,如聚合物、纳米材料和有机发光二极管(OLED)。它也是开发新型药物递送系统的一种有前途的材料。 | |||
T14069 |
A-3 hydrochloride
|
CaMK; Casein Kinase; PKA; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Neuroscience; Stem Cells; Tyrosine Kinase/Adaptors |
A-3 hydrochloride 是一种细胞可渗透的、可逆的、ATP 竞争性非选择性拮抗剂。它抑制 PKA 、酪蛋白激酶 II 和肌球蛋白轻链激酶,Ki 值分别为4.3 µM、5.1 µM 和7.4 µM。它还抑制 PKC 和酪蛋白激酶 I 的活性,Ki 分别为 47 µM 和 80 µM。 | |||
T31144 |
CycLuc2
CycLuc 2,CycLuc-2 |
||
CycLuc2 is a cyclic alkylaminoluciferin substrate for firefly luciferase. CycLuc2 emits 4.7-fold more light than aminoluciferin, and 2.6-fold more light than D-luciferin. | |||
T20096 |
Octabenzone
Seikalizer E,Rhodialux,Benzophenone 12,P Sanduvor 3035 |
||
Octabenzone protects damage against UV light. It also prevents skin cancer. | |||
T31145 |
CycLuc3
Cyc Luc 3,Cyc-Luc-3 |
||
CycLuc3 is a type of mutant firefly luciferase variant with enhanced light emission. | |||
T16145 |
MS-444
BE-34776 |
Others | Others |
MS-444 suppresses the activity of purified smooth muscle myosin light chain kinase (MLCK) (IC50: 10 μM). | |||
T33814 |
OptoDArG
Opto-DArG,Opto DArG |
||
OptoDArG is a diacylglycerol (DAG) photoswitch, which enables efficient control of TRPC3 by light. | |||
T33451 |
ML 7
ML7,ML-7 |
||
ML 7 is an inhibitor of myosin light chain kinase that protects cardiac function from ischemia/reperfusion (I/R) injury. | |||
T69377 |
BoNT-IN-33
|
||
BoNT-IN-33 is a potent inhibitor of Botulinum neurotoxin/A light chain (BoNT/A LC). | |||
T38229 | JF-NP-26 | ||
Caged Raseglurant . Releases raseglurant upon exposure to 405 nm (violet) light. Inhibits the effects of Quisqualate in cultured neurons when exposed to 405 nm light. Exhibits analgesic activity in pain models in vivo on photoactivation. Quantum yield = 0.18. Font et al (2017) Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator. eLIFE 6 e23545 PMID:28395733 | |||
T28287 |
PA1 2HCl
PA1,PA1 dihydrochloride |
||
PA1 2HCl is a blocker of photoswitchable epithelial sodium channel (ENaC). PA1 2HCl enables the optical control of ENaC channels, in particular the δβγ isoform, by switching between blue and green light, or by turning on and off blue light. | |||
T34777 |
Talaporfin free acid
Monoaspartyl chlorin,NPe6,Talaporfin,Aspartyl chlorin |
||
Talaporfin, an effective tumor localizer, can produce the selective degradation of tumor tissue following light exposure. | |||
T70626 |
MS 347a
|
||
MS 347a is a myosin light chain kinase (MLCK) inhibitor; an epoxide analog of sydowinin B (MS-347b). | |||
T25818 |
ML344
ML-344,ML 344 |
||
ML344 is a CqsS/LuxQ agonist probe that acts as an inducer of light production without autoinducers. | |||
T31552 |
DMNP-EDTA
DMNPEDTA,DM-Nitrophen,DM Nitrophen,DMNP EDTA |
||
DMNP-EDTA is a caged Ca2+ chelator which photouncages Cu2+ ions for light-controlled gene expression in yeast. | |||
T25890 |
NSC-84096
CID 256758,CID-256758,CID256758 |
||
NSC-84096 is an endopeptidase activity inhibitor of botulinum neurotoxin type A light chain (rBoNT/A-LC). |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8024 |
3-Indoleacetonitrile
|
Others; Endogenous Metabolite | Metabolism; Others |
3-Indoleacetonitrile 是内源性代谢产物的一种。 | |||
T5682 |
6-Hydroxyindole
|
Others | Others |
6-Hydroxyindole 是白色至浅棕色结晶或结晶性粉末。 | |||
T5771 |
Hypocrellin A
|
Antibacterial; PKC; Parasite | Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology |
Hypocrellin A 是一种天然的PKC 抑制剂,具有光诱导的抗肿瘤、抗真菌和抗病毒活性,还对 MHC 限制性抗原呈递发挥免疫调节作用。 | |||
T1391 |
4-Methylumbelliferone
Hymecromone,4-MU,胆通 |
Others | Others |
4-Methylumbelliferone (Hymecromone) 是透明质酸生物合成抑制剂,显示出抗肿瘤和抗转移活性。 | |||
TMA2394 |
DL-alpha-Tocopherol
DL-α-生育酚,消旋-α-生育酚,DL-α-Tocopherol,Alpha-Tochopherol,Ephanyl |
Antioxidant; Ferroptosis | Apoptosis; oxidation-reduction |
DL-alpha-Tocopherol (Ephanyl) 是一种合成维生素 E,能保护皮肤成纤维细胞免受紫外线的细胞毒性作用,具有抗氧化作用。 | |||
TMS2180 |
Zeaxanthin
Anchovyxanthin,All-Trans-Zeaxanthin,玉米 |
Antioxidant; Endogenous Metabolite | Metabolism; oxidation-reduction |
Zeaxanthin (All-Trans-Zeaxanthin) 是食物获得类胡萝卜素,存在于眼睛的黄斑部,具有抗氧化活性。 | |||
T1311 |
4-aminobenzoic acid
PABA,Vitamin H1,Vitamin Bx,para-Aminobenzoic acid,对氨基苯甲酸 |
Endogenous Metabolite | Metabolism |
4-aminobenzoic acid (para-Aminobenzoic acid) 是一种具有紫外线吸收和抗纤维化特性的有机酸。当暴露在光线下时,4-aminobenzoic acid 吸收紫外线并通过光化学反应释放多余的能量,这可能会对DNA造成损害。4-aminobenzoic acid 还可以增加组织水平的摄氧量,并可能增强单胺氧化酶(MAO)活性以促进血清素的降解,过量可能导致纤维化变化。 | |||
T2850 |
Bicuculline
荷包牡丹碱,(+)-Bicuculline,d-Bicuculline |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Bicuculline ((+)-Bicuculline) 是从东北延胡索中提取的一种生物碱,能阻断 Ca2+激活钾 (SK) 通道。它是一种竞争性的神经递质 GABAA 受体拮抗剂,IC50为 2 μM。 | |||
TN2286 |
Tsugaric acid A
|
NO Synthase | Immunology/Inflammation |
Tsugaric acid A 能够显著抑制超氧阴离子的形成,还可以保护人类角质形成细胞,使其免受紫外线 B 诱导的损害。 | |||
T1301 |
Guaiacol
O-methylcatechol,2-hydroxyanisole,o-methoxyphenol,2-Methoxyphenol,愈创木酚 |
NF-κB; COX; Endogenous Metabolite | Immunology/Inflammation; Metabolism; Neuroscience; NF-κB |
Guaiacol (2-Methoxyphenol) 是从小叶栲中提取的一种酚类,可抑制 LPS 刺激的COX-2表达和NF-κB 激活,具有抗炎活性。 | |||
T1659 |
Melatonin
Melatonine,松果体素,N-Acetyl-5-methoxytryptamine,褪黑素 |
CaMK; Apoptosis; Mitophagy; Estrogen/progestogen Receptor; Melatonin Receptor; Glutathione Peroxidase; Endogenous Metabolite; ROR; Autophagy | Apoptosis; Autophagy; Endocrinology/Hormones; GPCR/G Protein; Metabolism; Neuroscience |
Melatonin (Melatonine) 是一种由松果体制成的激素,可激活褪黑激素受体。它在睡眠中起作用,有抗氧化和抗炎特性。它是新型选择性ATF-6抑制剂,可诱导细胞凋亡。 | |||
T3851 |
Vicenin 2
Vicenin -2,维采宁 2,新西兰牡荆苷 |
RAAS | Endocrinology/Hormones |
Vicenin 2 来源于广金钱草 (Desmodium styracifolium) 的地上部分。Vicenin 2 是一种血管紧张素转换酶 (ACE) 抑制剂,IC50=43.83 μM。 | |||
TN4280 |
Isodictamnine
|
Others | Others |
Isodictamnine is phototoxic to certain bacteria and yeasts in long wave UV light. | |||
T10348 |
Apigenin-7-diglucuronide
|
Others | Others |
Apigenin-7-diglucuronide is a flavonoid glycoside that exists in an assortment of medicinal plants with anti-inflammatory or ant-oxidant activities. It protects retinas against bright light-induced photoreceptor degeneration through the inhibition of reti | |||
T60290 | Benzyl salicylate | ||
Benzyl salicylate 是一种水杨酸衍生物,可用作香料添加剂或紫外线吸收剂。 | |||
TN3276 |
8-Epixanthatin
|
Antifection | Microbiology/Virology |
8-Epixanthatin, a light-induced growth inhibitor, mediates the phototropic curvature in sunflower (Helianthus annuus) hypocotyls, it can induce germination of O. cumana at nano- to micromolar concentrations. 8-Epixanthatin has antiprotozoal activity. | |||
TN2736 | 2',6'-Dihydroxy-4'-methoxyacetophenone | Antifection | Microbiology/Virology |
2',6'-Dihydroxy-4'-methoxyacetophenone is a phytoalexin after fungal inoculation with Botrytis cinerea or UV light irradiation, it has spore germination inhibition on Botrytis cinerea and Phomopsis perniciosa, with ED50 values of 45 and 410 uM, respective | |||
T29607 |
Acid Red 88
11391 Red,Eniacid Fast Red A,Peony,Red No. 506 |
||
Acid red 88 is an anionic dye with potentially useful photocatalytic research applications. Acid red 88 has been used to determine the effect of Au deposition on ZnO photocatalytic activity under visible light. Additionally, the photocatalyst Au-TiO2 was | |||
T75608 | Myricetin 3-O-α-L-arabinopyranoside | ||
Myricetin 3-O-α-L-arabinopyranoside 抑制 A2E 光氧化诱导的RPE 细胞死亡。Myricetin 3-O-α-L-arabinopyranoside 对视网膜变性具有保护作用,可保护蓝光 (BL) 诱导对 RPE 细胞和小鼠模型的损伤。 | |||
T14047 |
5-Aminolevulinic acid
5-Amino-4-oxopentanoic acid |
Others | Others |
5-Aminolevulinic acid 是血红素合成的中间体,是卟啉合成途径中的一个化合物。它是一种光敏剂、抗肿瘤剂和前药。它也可以(以盐酸盐的形式)与蓝光照明结合使用,用于治疗面部或头皮的轻度至中度厚的光化性角化病。 |