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Search Results for " glucocorticoid "

154

抑制剂 & 化合物

19

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T37908	Glucocorticoid receptor agonist-1	Glucocorticoid Receptor	Endocrinology/Hormones
	Glucocorticoid receptor agonist-1是一种强效糖皮质激素受体激动剂，其 IC50 值为 2.8 nM。
T67742	EX-A5386 Glucocorticoid receptor modulator-1	Glucocorticoid Receptor	Endocrinology/Hormones
	EX-A5386 (Glucocorticoid receptor modulator-1)是一种有效的糖皮质激素受体调节剂，IC50/EC50<100nM。
T11417	Glucocorticoid receptor agonist	Others	Others
	Glucocorticoid receptor agonist is an effective glucocorticoid receptor agonist.
T9977	SGK1-IN-4	SGK	Metabolism
	SGK1-IN-4 是 SGK1 的特异性抑制剂，可用于骨关节炎研究。
T63539	Glucocorticoid receptor-IN-2
	Glucocorticoid receptor-IN-2 是糖皮质激素受体 (glucocorticoid receptor (GR)) 的选择性调节剂，表现出抗炎活性。Glucocorticoid receptor-IN-2 具有良好的转录抑制作用，能够作用于 hMMP1 (IC50: 0.171 nM)，也具有一定的转录激活作用，能够作用于 MMTV (EC50: 0.94 nM)。
T63551	Glucocorticoid receptor-IN-1
	Glucocorticoid receptor-IN-1 是糖皮质激素受体 (glucocorticoid receptor (GR)) 对选择性调节剂，表现出抗炎活性。Glucocorticoid receptor-IN-1 具有良好的转录抑制作用，能够作用于 hMMP1 (IC50: 2.11 nM)，也具有转录激活效果，能够作用于 MMTV (EC50: 5.59 nM)。
T72102	Glucocorticoid receptor modulator 1
	Glucocorticoid receptor modulator1 是一种高效且具有口服活性的 NF-κB 和 AP-1抑制剂，IC50分别为 9 nM 和 130 nM。Glucocorticoid receptor modulator1 可有效降低炎症因子 IL-6、IL-1β、TNF-α 的表达，可缓解小鼠皮炎。
T74697	Glucocorticoid receptor agonist-2
	Glucocorticoid receptoragonist-2 (compound 21) 作为一种糖皮质激素受体激动剂，具有 6.6 nM 的 IC50 值，主要用于抗炎 ADC 分子的合成。同时，它也是 ABBV-3373 的活性对照物。
T6635	EMD638683	SGK	Metabolism
	EMD638683 是一种具有抗高血压效力的新型 SGK 抑制剂，IC50=3 μM。
T2622	GSK 650394 GSK650394	SGK; Influenza Virus	Metabolism; Microbiology/Virology
	GSK 650394 是一种新颖的 SGK 抑制剂，可抑制流感病毒复制。它还是一种血清和糖皮质激素调节的激酶 1 抑制剂。
T14377	AZD5423	Glucocorticoid Receptor	Endocrinology/Hormones
	AZD5423 是可吸入的非甾体糖皮质激素受体选择性调节剂，能够有效降改善轻度过敏性哮喘患者的过敏原诱导反应。
T15451	GW-870086	Glucocorticoid Receptor	Endocrinology/Hormones
	GW-870086 是抗炎剂，是糖皮质激素受体激动剂，在 A549 细胞中，能够降低 NFκB 报告基因活性(pIC50: 10.1)。
T8777	Beclometasone 倍氯米松,BecloMethasone	Glucocorticoid Receptor	Endocrinology/Hormones
	Beclometasone 是糖皮质激素受体激动剂。
T77835	Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br
	Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br 为ADC linker，适用于ABBV-154、ABBV-927及ABBV-368或相似化合物的合成。
T82303	Glucocorticoid receptor agonist-1 phosphate Gly-Glu TFA
	Glucocorticoid receptor agonist-1 phosphate Gly-Glu (TFA) 是用于抗体-药物偶联物 (Antibody-Drug Conjugates (ADCs)) 合成的可降解 Linker。
T77869	Glucocorticoid receptor agonist-2 Ala-Ala-Mal
	Glucocorticoid receptor agonist-2 Ala-Ala-Mal（化合物79）是ABBV-3373的活性对照，可用于合成抗炎ADC分子。
T75130	Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br
	Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br 作为一种Drug-linker conjugates for ADC，主要用于抗CD40抗体活性分子偶联物 (ADCs) 的合成, 充当反应试剂。
T74116	Glucocorticoid receptor agonist-1 Ala-Ala-Mal
	Glucocorticoid receptoragonist-1 Ala-Ala-Mal (化合物 88) 是一种糖皮质激素，是糖皮质激素受体激动剂。Glucocorticoid receptoragonist-1 Ala-Ala-Mal 可与Adalimumab 偶联制备ADC。
T1163	Betamethasone valerate Betnovate,倍他米松戊酸酯,Betaderm,Betamethasone 17-valerate,Luxiq	Glucocorticoid Receptor	Endocrinology/Hormones
	Betamethasone valerate (Luxiq) 的 17 戊酸酯，是一种具有抗炎活性的局部皮质类固醇。它能够抑制放射标记的糖皮质激素地塞米松与人表皮(IC50:5 nM)及小鼠皮肤(IC50:6 nM)的结合。它可用于研究复发性口疮。
T14981	Clobetasone butyrate	Glucocorticoid Receptor	Endocrinology/Hormones
	Clobetasone butyrate 是糖皮质类固醇，特别是在皮肤上，具有局部抗炎活性。它可用于改善皮质类固醇反应性症状，如特应性皮炎、牛皮癣。
T17217	Vamorolone 地塞米松EP杂质E,VBP15	Glucocorticoid Receptor; NF-κB	Endocrinology/Hormones; NF-κB
	Vamorolone (VBP15) 是一种首创的，具有口服活性的解离性类固醇 (dissociative steroidal) 抗炎药和膜稳定剂。它抑制 (NF-κB) 抑制作用，并降低了激素的影响。它改善肌营养不良，无副作用。
T75016	Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal
	Glucocorticoid receptoragonist-1 phosphate Ala-Ala-Mal 是一种糖皮质激素受体激动剂。Glucocorticoid receptoragonist-1 phosphate Ala-Ala-Mal 可用于抗 CD40抗体偶联活性分子(ADC)。Glucocorticoid receptoragonist-1 phosphate Ala-Ala-Mal 可用于炎症和免疫调节的研究。
T3316	Fluorometholone 氟米龙,Fluoromethalone,Cortilet,Oxylone,Delmeson	Glucocorticoid Receptor	Endocrinology/Hormones
	Fluorometholone (Fluoromethalone) 是合成糖皮质激素，具有抗炎和抗过敏作用。它可用作糖皮质激素受体激动剂，能够用于干眼症的研究。
T0820	Triamcinolone acetonide 曲安奈德,Aristogel,Azmacort,Aristoderm	Glucocorticoid Receptor	Endocrinology/Hormones
	Triamcinolone acetonide (Azmacort) 是皮质类固醇。它是皮质类固醇激素受体激动剂。它是抗炎糖皮质激素，局部用于治疗各种皮肤疾病。它的有效性是 prednisone 的八倍。
T0261	Amcinonide 安西奈德,CL-34699	Glucocorticoid Receptor; Annexin A	Endocrinology/Hormones; GPCR/G Protein
	Amcinonide (CL-34699) 是皮质类固醇。它能够抑制NO 从活化的小胶质细胞释放(IC50:3.38 nM)，具有糖皮质激素受体亲和力。它是皮质类固醇激素受体激动剂。
T6502	Fluocinonide 醋酸氟轻松,Lidex,Metosyn,氟轻松,Topsyn	Glucocorticoid Receptor	Endocrinology/Hormones
	Fluocinonide (Topsyn) 是一种糖皮质激素类固醇，具有抗炎作用，可作用于皮肤疾病的研究。
T2526	Ciclesonide Zetonna,环索奈德,RPR251526,Omnaris,Alvesco	Glucocorticoid Receptor	Endocrinology/Hormones
	Ciclesonide (Alvesco) 是一种糖皮质激素，具有强效抗炎活性，可用于研究哮喘。
T1749	AL 082D06 D-06,AL082D06	Glucocorticoid Receptor	Endocrinology/Hormones
	AL 082D06 (D-06) 是非甾体类糖皮质激素受体 (GR) 选择性拮抗剂(Ki:210 nM)。
T8396	Prednisone acetate Prednisone 21-acetate,醋酸泼尼松	Glucocorticoid Receptor	Endocrinology/Hormones
	Prednisone acetate (Prednisone 21-acetate) 是泼尼松的醋酸盐形式，它是一种糖皮质激素受体激动剂，具有抗炎和免疫调节作用。
T0181	Loteprednol etabonate Lotemax,Alrex,氯替泼诺	Glucocorticoid Receptor; Antibacterial; Antibiotic	Endocrinology/Hormones; Microbiology/Virology
	Loteprednol etabonate (Lotemax) 是具有抗炎活性的皮质类固醇，用于眼科。
T1076	Dexamethasone MK 125,Prednisolone F,NSC 34521,Hexadecadrol,地塞米松	Glucocorticoid Receptor; Mitophagy; IL Receptor; SARS-CoV; Antibacterial; Antibiotic; Autophagy; Complement System	Autophagy; Endocrinology/Hormones; Immunology/Inflammation; Microbiology/Virology
	Dexamethasone (Hexadecadrol) 是一种糖皮质激素受体激动剂和一种 IL 受体调节剂。Dexamethasone 具有抗炎和免疫抑制活性，可诱导自噬。Dexamethasone 抑制 LPS 诱导的巨噬细胞炎症反应。
T0367	Fluocinolone (Acetonide) Fluocinolone acetonide,醋酸肤轻松,Flucort-N	Glucocorticoid Receptor	Endocrinology/Hormones
	Fluocinolone Acetonide (Flucort-N) 是一种糖皮质激素衍生物，能够作用于各种皮肤病的研究。
TQ0225	Velsecorat AZD7594,AZ13189620	Glucocorticoid Receptor	Endocrinology/Hormones
	Velsecorat (AZD7594) 是非甾体类糖皮质激素受体的选择性调节剂(IC50:0.9 nM)。
T6713	Ulipristal	Estrogen/progestogen Receptor; Progesterone Receptor	Endocrinology/Hormones; Others
	Ulipristal 是性孕酮受体 (progesterone receptor) 的选择性调节剂。它能够与孕激素受体结合，抑制 PR 介导的基因表达，降低生殖系统中孕激素的活性。
T0094	Budesonide Entocort,Pulmicort,布地奈德,Rhinocort	Glucocorticoid Receptor	Endocrinology/Hormones
	Budesonide (Pulmicort) 是吸入型糖皮质类固醇，是一种口服具有活性的糖皮质激素受体激动剂。它能够减小肺部肿瘤的体积，逆转 DNA 低度甲基化，调节基因的 mRNA 表达。它是能够用于哮喘的抗炎药。
T1531	Mometasone furoate 糠酸莫美他松,糠酸莫米松,Sch32088	Glucocorticoid Receptor	Endocrinology/Hormones
	Mometasone furoate (Sch32088) 是糖皮质激素受体激动剂，具有抗炎和抗过敏作用。它是皮质固醇类试剂，动物模型中，可局部应用于气道炎症、慢性皮肤湿疹、哮喘。
T22367	Methylprednisolone succinate Methylprednisolone hemisuccinate,Methylprednisolone hydrogen succinate,甲基泼尼松龙琥珀酸酯	Glucocorticoid Receptor	Endocrinology/Hormones
	Methylprednisolone succinate (Methylprednisolone hemisuccinate) 是合成的糖皮质激素，常用作抗炎剂。
T6580	Meprednisone SCH 4358,Methylprednisone,NSC 527579,Betanisona,Betapar,泼尼松	Glucocorticoid Receptor; Autophagy	Autophagy; Endocrinology/Hormones
	Meprednisone (Betapar) 是糖皮质激素，用于糖皮质激素受体，是泼尼松的甲基化衍生物。
T21404	Fluticasone furoate Veramyst,Allermist,Avamys,糠酸氟替卡松,Fluticasone furoate	Glucocorticoid Receptor	Endocrinology/Hormones
	Fluticasone furoate (Avamys) 是一种合成的三氟化皮质类固醇，衍生自氟替卡松，Kd 为 0.3 nM。Fluticasone furoate 具有有效的抗炎、抗哮喘活性和低全身暴露。Fluticasone furoate 可用作过敏性鼻炎治疗研究的鼻喷雾剂。
T2527	Ulipristal acetate Ulipristal,醋酸乌利司他,CDB-2914	Estrogen/progestogen Receptor; Progesterone Receptor; Autophagy	Autophagy; Endocrinology/Hormones; Others
	Ulipristal acetate (CDB-2914) 是一种具有抗孕酮活性的选择性孕酮受体调节剂。它可抑制子宫平滑肌瘤病的生长。它通过抑制或延迟排卵和影响子宫内膜组织，可用作紧急避孕药。
T16079	Mirodenafil 米罗那非,SK3530	PDE	Metabolism
	Mirodenafil 是一种磷酸二酯酶5（PDE-5）抑制剂，可用于勃起功能紊乱的研究。
T1127	Beclometasone dipropionate Beclovent,Beclomethasone dipropionate,二丙酸倍氯米松,丙酸倍氯米松,Beconase,Vancenase	Glucocorticoid Receptor	Endocrinology/Hormones
	Beclometasone dipropionate (Vancenase) 是具有口服活性的糖皮质激素，具有抗炎和免疫抑制作用。它是Betamethasone 的前体药物，Betamethasone 是 LPS 诱导的炎症及 MMP 释放的抑制剂。
T6503	Fluorometholone Acetate NSC 47438,Flarex,Eflone,氟米龙醋酸酯,Oxylone acetate	Glucocorticoid Receptor; Carbonic Anhydrase	Endocrinology/Hormones; Metabolism
	Fluorometholone Acetate (Oxylone acetate) 是合成的糖皮质激素皮质类固醇及皮质类固醇酯。它有效抑制碳酸酐酶 (CA) 对 hCA-I(IC50:2.18 μM)和 hCA-II(IC50:17.5 μM)。它具有抗炎活性，可用于研究外部眼部炎症。
T0947L	Dexamethasone Phosphate disodium 地塞米松磷酸二钠,EGP-437,EGP437. Dex-Phos,EGP 437	Glucocorticoid Receptor	Endocrinology/Hormones
	Dexamethasone Phosphate disodium (EGP437. Dex-Phos) 是糖皮质激素受体激动剂。
T0208	Prednisolone disodium phosphate 泼尼松龙21-磷酸二钠,Prednisolone phosphate sodium,Prednisolone 21-phosphate disodium,泼尼松龙磷酸钠	Glucocorticoid Receptor	Endocrinology/Hormones
	Prednisolone disodium phosphate是一种合成的糖皮质素，具有抗炎和免疫调节作用。
T0188	Fluticasone (propionate) 丙酸氟替卡松,CCI-187881,氟替卡松丙酸酯,Fluticasone propionate	Glucocorticoid Receptor; Virus Protease; Estrogen/progestogen Receptor; Phospholipase; Endogenous Metabolite	Endocrinology/Hormones; Metabolism; Microbiology/Virology
	Fluticasone propionate (CCI-187881) 是一种选择性糖皮质激素受体激动剂，是一种局部抗炎激素，亲和力KD 为 0.5 nM。具有抗病毒活性。
T19913	CKI-7 CKI 7 2HCl,CKI-7 dihydrochloride,N-(2-氨基乙基)-5-氯异喹啉-8-磺酰胺二盐酸盐,CKI7 2HCl,CKI 7 dihydrochloride,CKI7 dihydrochloride,CKI-7 2HCl	ROCK; SGK; Casein Kinase; CDK; S6 Kinase	Cell Cycle/Checkpoint; Cytoskeletal Signaling; MAPK; Metabolism; PI3K/Akt/mTOR signaling; Stem Cells
	CKI-7 是一种有效且 ATP 竞争性的酪蛋白激酶 1 抑制剂，IC50为 6 μM，Ki 为 8.5 μM。它选择性抑制 Cdc7激酶，还抑制 SGK，S6K1以及 MSK1。
T1559	Betamethasone dipropionate Diprolene AF,SCH 11460,二丙酸倍他米松,Betamethasone 17,21-dipropionate,Diprolene,倍他米松二丙酸酯,Diprosone	Glucocorticoid Receptor	Endocrinology/Hormones
	Betamethasone dipropionate (SCH 11460) 是糖皮质激素类固醇，具有免疫抑制、抗炎作用。
T1102	Mifepristone C-1073,RU486,RU 38486,米非司酮	Glucocorticoid Receptor; Estrogen/progestogen Receptor; Progesterone Receptor; NO Synthase; Autophagy	Autophagy; Endocrinology/Hormones; Immunology/Inflammation; Others
	Mifepristone (C-1073) 是一种黄体酮受体和糖皮质激素受体拮抗剂，在体外实验中的 IC50值分别为 0.2 nM 和 2.6 nM。
T0947	Dexamethasone acetate Dexamethasone 21-acetate,醋酸地塞米松,Dexamethason acetate,NSC 39471	Glucocorticoid Receptor; Mitophagy; IL Receptor; Annexin A; NOS; Antibacterial; Autophagy	Autophagy; Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology
	Dexamethasone acetate (NSC 39471) 是一种糖皮质素类甾体，有抗炎和免疫抑制活性。它可研究眼部感染。

化合物

Glucocorticoid receptor agonist-1

Cat.No: T37908

Target: Glucocorticoid Receptor

Cat.No: T67742

Synonym: Glucocorticoid receptor modulator-1

Target: Glucocorticoid Receptor

Glucocorticoid receptor agonist

Cat.No: T11417

Target: Others

Cat.No: T9977

Target: SGK

Glucocorticoid receptor-IN-2

Cat.No: T63539

Glucocorticoid receptor-IN-1

Cat.No: T63551

Glucocorticoid receptor modulator 1

Cat.No: T72102

Glucocorticoid receptor agonist-2

Cat.No: T74697

Cat.No: T6635

Target: SGK

Cat.No: T2622

Synonym: GSK650394

Target: SGK, Influenza Virus

Cat.No: T14377

Target: Glucocorticoid Receptor

Cat.No: T15451

Target: Glucocorticoid Receptor

Cat.No: T8777

Synonym: 倍氯米松,BecloMethasone

Target: Glucocorticoid Receptor

Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br

Cat.No: T77835

Glucocorticoid receptor agonist-1 phosphate Gly-Glu TFA

Cat.No: T82303

Glucocorticoid receptor agonist-2 Ala-Ala-Mal

Cat.No: T77869

Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br

Cat.No: T75130

Glucocorticoid receptor agonist-1 Ala-Ala-Mal

Cat.No: T74116

Betamethasone valerate

Cat.No: T1163

Synonym: Betnovate,倍他米松戊酸酯,Betaderm,Betamethasone 17-valerate,Luxiq

Target: Glucocorticoid Receptor

Clobetasone butyrate

Cat.No: T14981

Target: Glucocorticoid Receptor

Cat.No: T17217

Synonym: 地塞米松EP杂质E,VBP15

Target: Glucocorticoid Receptor, NF-κB

Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal

Cat.No: T75016

Fluorometholone

Cat.No: T3316

Synonym: 氟米龙,Fluoromethalone,Cortilet,Oxylone,Delmeson

Target: Glucocorticoid Receptor

Triamcinolone acetonide

Cat.No: T0820

Synonym: 曲安奈德,Aristogel,Azmacort,Aristoderm

Target: Glucocorticoid Receptor

Cat.No: T0261

Synonym: 安西奈德,CL-34699

Target: Glucocorticoid Receptor, Annexin A

Cat.No: T6502

Synonym: 醋酸氟轻松,Lidex,Metosyn,氟轻松,Topsyn

Target: Glucocorticoid Receptor

Cat.No: T2526

Synonym: Zetonna,环索奈德,RPR251526,Omnaris,Alvesco

Target: Glucocorticoid Receptor

Cat.No: T1749

Synonym: D-06,AL082D06

Target: Glucocorticoid Receptor

Prednisone acetate

Cat.No: T8396

Synonym: Prednisone 21-acetate,醋酸泼尼松

Target: Glucocorticoid Receptor

Loteprednol etabonate

Cat.No: T0181

Synonym: Lotemax,Alrex,氯替泼诺

Target: Glucocorticoid Receptor, Antibacterial, Antibiotic

Cat.No: T1076

Synonym: MK 125,Prednisolone F,NSC 34521,Hexadecadrol,地塞米松

Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, SARS-CoV, Antibacterial, Antibiotic, Autophagy, Complement System

Fluocinolone (Acetonide)

Cat.No: T0367

Synonym: Fluocinolone acetonide,醋酸肤轻松,Flucort-N

Target: Glucocorticoid Receptor

Cat.No: TQ0225

Synonym: AZD7594,AZ13189620

Target: Glucocorticoid Receptor

Cat.No: T6713

Target: Estrogen/progestogen Receptor, Progesterone Receptor

Cat.No: T0094

Synonym: Entocort,Pulmicort,布地奈德,Rhinocort

Target: Glucocorticoid Receptor

Mometasone furoate

Cat.No: T1531

Synonym: 糠酸莫美他松,糠酸莫米松,Sch32088

Target: Glucocorticoid Receptor

Methylprednisolone succinate

Cat.No: T22367

Synonym: Methylprednisolone hemisuccinate,Methylprednisolone hydrogen succinate,甲基泼尼松龙琥珀酸酯

Target: Glucocorticoid Receptor

Cat.No: T6580

Synonym: SCH 4358,Methylprednisone,NSC 527579,Betanisona,Betapar,泼尼松

Target: Glucocorticoid Receptor, Autophagy

Fluticasone furoate

Cat.No: T21404

Synonym: Veramyst,Allermist,Avamys,糠酸氟替卡松,Fluticasone furoate

Target: Glucocorticoid Receptor

Ulipristal acetate

Cat.No: T2527

Synonym: Ulipristal,醋酸乌利司他,CDB-2914

Target: Estrogen/progestogen Receptor, Progesterone Receptor, Autophagy

Cat.No: T16079

Synonym: 米罗那非,SK3530

Target: PDE

Beclometasone dipropionate

Cat.No: T1127

Synonym: Beclovent,Beclomethasone dipropionate,二丙酸倍氯米松,丙酸倍氯米松,Beconase,Vancenase

Target: Glucocorticoid Receptor

Fluorometholone Acetate

Cat.No: T6503

Synonym: NSC 47438,Flarex,Eflone,氟米龙醋酸酯,Oxylone acetate

Target: Glucocorticoid Receptor, Carbonic Anhydrase

Dexamethasone Phosphate disodium

Cat.No: T0947L

Synonym: 地塞米松磷酸二钠,EGP-437,EGP437. Dex-Phos,EGP 437

Target: Glucocorticoid Receptor

Prednisolone disodium phosphate

Cat.No: T0208

Synonym: 泼尼松龙21-磷酸二钠,Prednisolone phosphate sodium,Prednisolone 21-phosphate disodium,泼尼松龙磷酸钠

Target: Glucocorticoid Receptor

Fluticasone (propionate)

Cat.No: T0188

Synonym: 丙酸氟替卡松,CCI-187881,氟替卡松丙酸酯,Fluticasone propionate

Target: Glucocorticoid Receptor, Virus Protease, Estrogen/progestogen Receptor, Phospholipase, Endogenous Metabolite

Cat.No: T19913

Synonym: CKI 7 2HCl,CKI-7 dihydrochloride,N-(2-氨基乙基)-5-氯异喹啉-8-磺酰胺二盐酸盐,CKI7 2HCl,CKI 7 dihydrochloride,CKI7 dihydrochloride,CKI-7 2HCl

Target: ROCK, SGK, Casein Kinase, CDK, S6 Kinase

Betamethasone dipropionate

Cat.No: T1559

Synonym: Diprolene AF,SCH 11460,二丙酸倍他米松,Betamethasone 17,21-dipropionate,Diprolene,倍他米松二丙酸酯,Diprosone

Target: Glucocorticoid Receptor

Cat.No: T1102

Synonym: C-1073,RU486,RU 38486,米非司酮

Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, NO Synthase, Autophagy

Dexamethasone acetate

Cat.No: T0947

Synonym: Dexamethasone 21-acetate,醋酸地塞米松,Dexamethason acetate,NSC 39471

Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, Annexin A, NOS, Antibacterial, Autophagy

Cat. No.	Product Name	Target	Signaling Pathways
T1560	Prednisolone 氢化泼尼松,Predonine,Hydroretrocortine,泼尼松龙,Metacortandralone	Glucocorticoid Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Prednisolone (Hydroretrocortine) 是有口服活性的皮质类固醇和糖皮质激素。它的抗炎特性约为氢化可的松的四倍，同时减少了水和盐的保留。它能够用于眼部抗炎研究。
T1614	Hydrocortisone 氢化可的松,Cortisol	Glucocorticoid Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Hydrocortisone (Cortisol) 是一种糖皮质激素，由肾上腺素皮质分泌。Hydrocortisone 激动糖皮质激素受体，可促进蛋白质分解代谢、糖异生、毛细血管壁稳定性、肾脏钙排泄，并抑制免疫和炎症反应。
T1168	Desonide Tridesilon,地索奈德,Locapred,Prednacinolone	Glucocorticoid Receptor	Endocrinology/Hormones
	Desonide (Prednacinolone) 是一种非氟化皮质类固醇抗炎剂，能够作用于糖皮质激素受体。
T0798	Triamcinolone Fluoxyprednisolone,曲安西龙,Aristocort,Rodinolone	Glucocorticoid Receptor; COX	Endocrinology/Hormones; Immunology/Inflammation; Neuroscience
	Triamcinolone (Aristocort) 是一种皮质类固醇激素受体激动剂，也是一种合成的长效糖皮质激素，具有抗炎活性。
T2884	Cortisone Kendall's compound E,17-Hydroxy-11-dehydrocorticosterone,可的松	Glucocorticoid Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Cortisone (17-Hydroxy-11-dehydrocorticosterone) 是 Cortisol(一种糖皮质激素)的氧化代谢产物。Cortisone 具有消炎和免疫抑制的作用。Cortisone 在高浓度下对 Glucocorticoid 与Glucocorticoid-receptor 的结合具有部分干预作用。
T1243	Hydrocortisone acetate Cortisol 21-acetate,Hydrocortisone 21-acetate,醋酸氢化可的松	Glucocorticoid Receptor; Annexin A; Endogenous Metabolite	Endocrinology/Hormones; GPCR/G Protein; Metabolism
	Hydrocortisone acetate (Cortisol 21-acetate) 是皮质类固醇，能够减少轻微皮肤刺激或痔疮引起的肿胀、搔痒和疼痛。
T0034	Cortisone acetate 醋酸可的松,Cortisone 21-acetate,NSC 49420	Glucocorticoid Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Cortisone acetate (NSC-49420) 是 Cortisol(一种糖皮质激素)的氧化代谢产物。它在高浓度下能够部分干预 Glucocorticoid 与Glucocorticoid-receptor 的结合。它具有免疫抑制和消炎的作用。
T2810	(20S)-Protopanaxatriol 原人参三醇,20(S)-APPT,20 (S)-原人参三醇,g-PPT	Apoptosis; Estrogen Receptor/ERR; Glucocorticoid Receptor; Estrogen/progestogen Receptor; Liver X Receptor	Apoptosis; Endocrinology/Hormones; Metabolism
	(20S)-Protopanaxatriol (g-PPT) 是人参皂苷的代谢物，通过糖皮质激素受体和雌激素受体起作用，同时为LXRα的抑制剂，具有广泛的抗癌活性。
T2748	Cortodoxone 可托多松,11-Deoxycortisol,cortexolone,17α,21-dihydroxyprogesterone,Reichstein's substance S,11-Desoxycortisol	Glucocorticoid Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Cortodoxone (11-Desoxycortisol) 是糖皮质类固醇激素，能够氧化为皮质醇。
T1261	Medroxyprogesterone Acetate Medroxyprogesterone 17-acetate,Provera,Metigestrona,NSC-26386,醋酸甲羟孕酮,Farlutin,安宫黄体酮,Medroxyprogesterone (acetate)	Glucocorticoid Receptor; Estrogen/progestogen Receptor; Progesterone Receptor; Androgen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism; Others
	Medroxyprogesterone Acetate (Farlutin) 是广泛使用的合成类固醇，与雄激素，孕酮及糖皮质激素受体均有作用。
T0948L	Corticosterone 皮质酮,17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,肾上腺酮,Corticosterone (From plants)	Glucocorticoid Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Corticosterone (Kendall's compound B) 是一种肾上腺皮质类固醇，有盐皮质激素和糖皮质激素的活性，具有口服活性。Corticosterone 参与体内能量、免疫反应和应激反应的调节。
T0269	Dichlorisone Acetate 糊状叶绿素,Diloderm,醋酸二氯松	Endogenous Metabolite; AChE	Metabolism; Neuroscience
	Dichlorisone Acetate (Diloderm) 一种是合成的糖皮质激素皮质类固醇，具有抗炎特性。
T1683	Actriol 异雌三醇,Epiestriol	Glucocorticoid Receptor	Endocrinology/Hormones
	Actriol (Epiestriol) 是内源性雌激素雌酮的代谢物，拥有抗炎及抗菌活性。
T6343	Geldanamycin 格尔德霉素,NSC 122750	HSP; Influenza Virus; Tyrosine Kinases; Antibacterial; Antibiotic	Cytoskeletal Signaling; Metabolism; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Geldanamycin 是一种 HSP90 抑制剂（Kd：1.2 μM），可特异性破坏糖皮质激素受体 (GR)/HSP 的结合。
T1429	17α-Hydroxyprogesterone Hydroxyprogesterone,17-OHP,羟孕酮,17-Hydroxyprogesterone,17α-羟孕酮	Estrogen/progestogen Receptor; Progesterone Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism; Others
	17α-Hydroxyprogesterone (17-OHP) 是一种内源性孕激素，其他类固醇激素（包括糖皮质激素，雌激素，和雄激素）生物合成的化学中间体。
T2S2043	Dracorhodin perchlorate Dracorhodin perochlorate,血竭素高氯酸盐,Dracohodin perochlorate	Apoptosis; Others	Apoptosis; Others
	Dracorhodin perchlorate 是来源于中药血竭的一种天然产物。它抑制细胞生长，并以剂量和时间依赖性方式诱导成纤维细胞凋亡，将细胞周期阻滞在 G1 期，可作为抗乳腺癌的候选药物。
T5S2343	Acetylshikonin 乙酰紫草素,Acetyl shikonin	Others; P450; AChE	Metabolism; Neuroscience; Others
	Acetylshikonin 来源于紫草根，具有抗癌、抗炎作用。它是一种 AChE 抑制剂，具有很强的抗凋亡活性。它是一种非选择性的细胞色素 P450抑制剂，对所有 P450 亚型抑制的 IC50值范围为 1.4-4.0 μM。
TN3537	Braylin	IL Receptor; TNF; NF-κB	Apoptosis; Immunology/Inflammation; NF-κB
	Braylin has anti-inflammatory, antinociceptive and immunomodulatory effects, which possibly act through the glucocorticoid receptor activation and by inhibition of the transcriptional activity of NF-ÎºB. Braylin is also a phosphodiesterase-4 inhibitor, it could represent an ideal prototype of glucocorticoid receptor ligand, able to induce synergic immunomodulatory effects.
T13517	Allotetrahydrocortisol 5a-Tetrahydrocortisol	Others	Others
	Allotetrahydrocortisol (5a-Tetrahydrocortisol) is a metabolite of Cortisol. Cortisol is the main glucocorticoid in human.

天然产物

Cat.No: T1560

Synonym: 氢化泼尼松,Predonine,Hydroretrocortine,泼尼松龙,Metacortandralone

Target: Glucocorticoid Receptor, Endogenous Metabolite

Cat.No: T1614

Synonym: 氢化可的松,Cortisol

Target: Glucocorticoid Receptor, Endogenous Metabolite

Cat.No: T1168

Synonym: Tridesilon,地索奈德,Locapred,Prednacinolone

Target: Glucocorticoid Receptor

Cat.No: T0798

Synonym: Fluoxyprednisolone,曲安西龙,Aristocort,Rodinolone

Target: Glucocorticoid Receptor, COX

Cat.No: T2884

Synonym: Kendall's compound E,17-Hydroxy-11-dehydrocorticosterone,可的松

Target: Glucocorticoid Receptor, Endogenous Metabolite

Hydrocortisone acetate

Cat.No: T1243

Synonym: Cortisol 21-acetate,Hydrocortisone 21-acetate,醋酸氢化可的松

Target: Glucocorticoid Receptor, Annexin A, Endogenous Metabolite

Cortisone acetate

Cat.No: T0034

Synonym: 醋酸可的松,Cortisone 21-acetate,NSC 49420

Target: Glucocorticoid Receptor, Endogenous Metabolite

(20S)-Protopanaxatriol

Cat.No: T2810

Synonym: 原人参三醇,20(S)-APPT,20 (S)-原人参三醇,g-PPT

Target: Apoptosis, Estrogen Receptor/ERR, Glucocorticoid Receptor, Estrogen/progestogen Receptor, Liver X Receptor

Cat.No: T2748

Synonym: 可托多松,11-Deoxycortisol,cortexolone,17α,21-dihydroxyprogesterone,Reichstein's substance S,11-Desoxycortisol

Target: Glucocorticoid Receptor, Endogenous Metabolite

Medroxyprogesterone Acetate

Cat.No: T1261

Synonym: Medroxyprogesterone 17-acetate,Provera,Metigestrona,NSC-26386,醋酸甲羟孕酮,Farlutin,安宫黄体酮,Medroxyprogesterone (acetate)

Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, Androgen Receptor, Endogenous Metabolite

Cat.No: T0948L

Synonym: 皮质酮,17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,肾上腺酮,Corticosterone (From plants)

Target: Glucocorticoid Receptor, Endogenous Metabolite

Dichlorisone Acetate

Cat.No: T0269

Synonym: 糊状叶绿素,Diloderm,醋酸二氯松

Target: Endogenous Metabolite, AChE

Cat.No: T1683

Synonym: 异雌三醇,Epiestriol

Target: Glucocorticoid Receptor

Cat.No: T6343

Synonym: 格尔德霉素,NSC 122750

Target: HSP, Influenza Virus, Tyrosine Kinases, Antibacterial, Antibiotic

17α-Hydroxyprogesterone

Cat.No: T1429

Synonym: Hydroxyprogesterone,17-OHP,羟孕酮,17-Hydroxyprogesterone,17α-羟孕酮

Target: Estrogen/progestogen Receptor, Progesterone Receptor, Endogenous Metabolite

Dracorhodin perchlorate

Cat.No: T2S2043

Synonym: Dracorhodin perochlorate,血竭素高氯酸盐,Dracohodin perochlorate

Target: Apoptosis, Others

Cat.No: T5S2343

Synonym: 乙酰紫草素,Acetyl shikonin

Target: Others, P450, AChE

Cat.No: TN3537

Target: IL Receptor, TNF, NF-κB

Allotetrahydrocortisol

Cat.No: T13517

Synonym: 5a-Tetrahydrocortisol

Target: Others

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