426
46
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T38260 |
SP 600125, negative control
JNK Inhibitor II, negative control |
||
SP 600125, negative control 是 SP 600125 的甲基化类似物,可用作SP 600125的阴性对照,对 DTP3和GADD45β/MKK7(生长停滞和 DNA 损伤诱导型 β/介原活化蛋白激酶激酶 7)具有抑制作用,能够恢复活化。SP 600125, negative control 对 JNK2 和 JNK3 的 IC50s 分别为 18 和 24 μM。 | |||
TP1555L1 |
Fibronectin Active Fragment Control acetate
Fibronectin Active Fragment Control acetate(97461-84-2 Free base) |
||
Fibronectin Active Fragment Control acetate 是纤连蛋白的活性片段,这是一种糖蛋白。 | |||
TP1833L |
SLLK, Control Peptide for TSP1 Inhibitor acetate
SLLK, Control Peptide for TSP1 Inhibitor acetate(464924-27-4,free base) |
Others | Others |
SLLK, Control Peptide for TSP1 Inhibitor acetate(464924-27-4,free base) 是 LSKL 的对照肽。 | |||
TP2180L |
Compstatin control peptide acetate
|
Complement System | Immunology/Inflammation |
Compstatin control peptide acetate 是补体蛋白 C3 的抑制剂,通过结合和抑制补体 C3 的切割。 | |||
T37559 |
NF-κB Control
|
||
NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α. NF-κB control is a peptide that is identical in sequence to NF-κB inhibitor, except two essential, basic residues of the p105 NLS are substituted with non-basic amino acids... | |||
T39317 |
ELA-14 negative control
|
||
ELA-14 negative control is an inactive peptide that serves as a negative control for ELA-14. | |||
T41227 |
ARCC 4 negative control
|
||
ARCC 4 negative control is a negative control for ARCC 4. Binds androgen receptors (AR) without inducing degradation. | |||
T78337 |
Mouse IgG2a kappa, Isotype Control
|
||
Mouse IgG2a kappa, Isotype Control 是鼠源IIgG2a kappa 抗体的同型抗体。 | |||
TP1357 |
Human IgG1 Control
|
||
Human IgG1 Control was purified from Human serum by chromatography.Human IgG1 Control can be used as a Control, standard, blocking agent, or coating protein in a variety of experiments, including ELISA, Western and blotting, immunoprecipitation, and immun | |||
TP2130L |
Rac1 Inhibitor F56, control peptide acetate
Rac1 Inhibitor F56, control peptide acetate(1315378-77-8 free base) |
Rho | Cell Cycle/Checkpoint |
Rac1 Inhibitor F56, control peptide acetate(1315378-77-8 free base) 是 Rac1 Inhibitor 的对照肽版本;包含Rac1的残基45-60,其中Trp56被Phe 取代。不影响 GEF-Rac1 相互作用。 | |||
T36580 |
Glucagon Receptor Antagonist Inactive Control
|
||
Glucagon Receptor Antagonist Inactive Control 是一种 Glucagon 受体拮抗剂,可用于生命科学领域的相关研究。其产品编号为 T36580,CAS号为 362482-00-6。 | |||
T36247 |
TBK1 control PROTAC® 4
|
||
Negative control for TBK1 PROTAC 3i. Binds TBK1 with high affinity, but exhibits no significant degradation of TBK1. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. | |||
TP1833 |
SLLK, Control Peptide for TSP1 Inhibitor(TFA)
SLLK, Control Peptide for TSP1 Inhibitor,SLLK,TSP1抑制剂控制肽 |
||
SLLK is a control peptide for LSKL. | |||
TP1450 |
SLLK, Control Peptide for TSP1 Inhibitor(TFA) (464924-27-4 free base)
SLLK, Control Peptide for TSP1 Inhibitor(TFA) |
||
SLLK, Control Peptide for TSP1 Inhibitor (TFA) is a control peptide for LSKL, which is a Thrombospondin (TSP-1) inhibitor. | |||
TP1555 |
Fibronectin Active Fragment Control
|
||
Fibronectin is a high-molecular weight (~440kDa) extracellular matrix glycoprotein that binds to membrane-spanning receptor proteins called integrins.In addition to integrins, fibronectin also binds extracellular matrix components such as collagen, fibrin | |||
TP2130 |
Rac1 Inhibitor F56, control peptide
|
||
Control peptide version of Rac1 Inhibitor; comprises residues 45-60 of Rac1 with Trp56 replaced by Phe. Does not affect GEF-Rac1 interaction. | |||
TP2203 |
Bax inhibitor peptide, negative control
|
Others | Others |
The compound is a negative control peptide for the Bax inhibitor peptides V5 and P5. | |||
TP2039 |
Dynamin inhibitory peptide, myristoylated (control)
|
||
Control peptide version of dynamin inhibitory peptide, myristoylated, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. In contrast to dynamin inhibitory peptide, has no significant eff | |||
T71316 |
ERK Inhibitor II (Negative control)
|
||
ERK InhibitorII (Negative control)为高效的细胞外信号调节激酶(ERK)抑制剂,能抑制胰岛素受体(Insulin Receptor)激活,适用于糖尿病研究。 | |||
T41214 |
(S)-BAY-293
BAY 294,BAY 293 Negative Control |
Ras | GPCR/G Protein; MAPK |
(S)-BAY-293 是一种有效的 pan-KRAS 抑制剂,可用于研究原发性非小肺癌和胰腺癌。 | |||
T35059 |
VinSpinIC
Vinnie's Spindlin Inactive Control,TD020826a |
||
VinSpinIC is an inactive control for VinSpinIn. | |||
T74869 | SiRNA Negative Control | ||
SiRNA Negative Control 是 21个核苷酸的 siRNA,可作为阴性对照使用。 | |||
T23150 |
PHGDH-inactive
|
Others | Others |
PHGDH-inactive 对 PHGDH 无活性,IC50大于57 μM,可用作 NCT-502 和 NCT-503 的阴性对照。 | |||
T81317 |
Rabbit IgG1 kappa, Isotype Control
|
||
RabbitIgG1kappa, Isotype Control为兔源IgG1κ同型对照单克隆抗体,用于科研中作为Rabbit IgG1κ抗体的实验对照。 | |||
T78338 |
Rat IgG1 kappa, Isotype Control
|
||
RatIgG1kappa(Isotype Control)是Rat IgG1κ抗体同型对照的鼠源性单克隆抗体。 | |||
T78243 | Human IgG2 kappa, Isotype Control | ||
HumanIgG2kappa, Isotype Control为人源化单克隆抗体,作为human IgG2κ抗体的标准同型对照使用。 | |||
T78244 |
Human IgG4 kappa, Isotype Control
|
||
HumanIgG4kappa Isotype Control为人源化单克隆抗体,用作human IgG4κ抗体的同型对照。 | |||
T81756 |
Mouse IgG3 kappa, Isotype Control
|
||
MouseIgG3kappa, Isotype Control为鼠源单克隆抗体,充当mouse IgG3κ抗体的同型对照。 | |||
T81757 |
Mouse IgG2c kappa, Isotype Control
|
||
MouseIgG2ckappa, Isotype Control为mouse IgG2cκ同型对照的鼠源单克隆抗体。 | |||
T81758 |
Mouse IgG2b kappa, Isotype Control
|
||
MouseIgG2bkappa Isotype Control是mouse IgG2bκ抗体的同型对照,属于鼠源单克隆抗体。 | |||
T78336 |
Mouse IgG1 kappa, Isotype Control
|
||
MouseIgG1kappa Isotype Control 为 mouse IgG1κ 抗体的同型对照鼠源单克隆抗体。 | |||
T19578 |
TH-263
|
Others | Others |
TH-263 是二芳基磺酰胺衍生物,可用作 TH-257 的阴性对照,对 LIMK1 和 LIMK2 均无抑制活性。 | |||
T82157 |
Human IgG1 lambda1, Isotype Control
|
||
HumanIgG1lambda1, Isotype Control为人-鼠嵌合型单克隆抗体,作为human IgG1λ1抗体的同型对照物。 | |||
T78242 |
Human IgG1 kappa, Isotype Control
|
||
HumanIgG1kappa, Isotype Control为人源化单克隆抗体,作为human IgG1κ抗体的同型对照物。 | |||
T82156 |
Human IgG3 kappa, Isotype Control
|
||
HumanIgG3kappa, Isotype Control为人-鼠嵌合型抗体,作为human IgG3κ抗体同型对照使用。 | |||
T15441 |
GSK8573
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
GSK8573 是 GSK2801 的非活性对照化合物。它与BRD9具有结合活性,Kd 值为 1.04 μM。 | |||
T78041 |
Tat-peptide control 168-189 TFA
|
||
Tat-peptide 168-189 是一款标记有 Tat 的细胞渗透融合肽,对应回大鼠 G3BP1 的168-189残基。此配合物末端整合了HIV Tat 序列的一个高度非保守部分,以促进其穿透细胞膜。作为Tat-peptide 168-189 TFA的阴性对照,Tat-peptide 168-189 TFA 已被证实可促进轴突生长和增加神经元的突触数目。 | |||
T78340 |
Human IgG1 (N297A) kappa, Isotype Control
|
||
HumanIgG1(N297A) kappa, Isotype Control为具有人-鼠嵌合结构的抗体,作为HumanIgG1(N297A)κ 抗体的同型对照物。 | |||
T78341 |
Human IgG1 (F405L) kappa, Isotype Control
|
||
HumanIgG1(F405L) kappa, Isotype Control为人-鼠嵌合型单克隆抗体,作为HumanIgG1(F405L)κ抗体的同型对照使用。 | |||
T82155 |
Human IgG4 (S228P) lambda1, Isotype Control
|
||
HumanIgG4(S228P) lambda1, Isotype Control,为人-鼠嵌合型抗体,作为humanIgG4(S228P) λ1抗体同型对照使用。 | |||
T82161 |
Human IgG1 (D265A) kappa, Isotype Control
|
||
HumanIgG1(D265A) kappa, Isotype Control是一种人鼠嵌合型抗体,用作HumanIgG1(D265A)κ抗体的同型对照。 | |||
T81755 |
Mouse lgG2a (D265A) kappa, Isotype Control
|
||
Mouse lgG2a (D265A) kappa, Isotype Control 为 mouse lgG2a (D265A) 的鼠源单克隆同型对照抗体。 | |||
T81759 |
Mouse IgG1 (N297A) kappa, Isotype Control
|
||
MouseIgG1(N297A) kappa,Isotype Control 为特定mouse IgG1(N297A)κ 抗体之同型对照,属鼠源单克隆抗体。 | |||
T0961 |
Trometamol
三(羟甲基)氨基甲烷,Tromethamine,缓血酸铵 |
COX | Immunology/Inflammation; Neuroscience |
Trometamol (Tromethamine) 是一种在生理范围内控制 pH 值的有效胺类化合物,也是一种低毒性的生物惰性氨基醇,可以在体内和体外缓冲二氧化碳和酸。 | |||
T24677 |
PS47
PS 47,PS-47 |
PDK | PI3K/Akt/mTOR signaling |
PS-47(PS 47) 是一种 PS48 的非活性 E-异构体。其中 PS48 是一种 PDK1 的激活剂。PS47 (PS 47) 可用作 PS48 的阴性对照。 | |||
T81760 |
Mouse IgG1 (D265A) kappa, Isotype Control
|
||
MouseIgG1(D265A) kappa, Isotype Control 为鼠源IgG1 κ类同型对照单克隆抗体,适用作为mouse IgG1(D265A)κ抗体的实验对照。 | |||
T78339 |
Human IgG4 (S228P) kappa, Isotype Control
|
||
HumanIgG4(S228P) kappa, Isotype Control为人-鼠嵌合型单克隆抗体,作为humanIgG4(S228P)κ抗体的同型对照使用。 | |||
T82159 |
Human IgG1 (K214R) kappa, Isotype Control
|
||
HumanIgG1(K214R) kappa, Isotype Control为HumanIgG1(K214R)κ 抗体的人源化同型对照,属于人-鼠嵌合型抗体。 | |||
T82160 |
Human IgG1 (D270N) kappa, Isotype Control
|
||
HumanIgG1(D270N) kappa, Isotype Control为人-鼠嵌合型抗体, 作为HumanIgG1(D270N)κ 抗体的同型对照品。 | |||
T8543 |
KN-92 hydrochloride
|
CaMK | Neuroscience |
KN-92 hydrochloride 是 KN-93 的非活性衍生物,对 CaM 激酶无抑制作用。它可作为对照化合物用于阐明 KN-93 的拮抗活性。KN-93 是一种可渗透细胞的、可逆的、竞争性的 CaMKII 抑制剂。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6S2243 |
Alisol A 24-acetate
Alisol A 24-monoacetate,Alisol A monoacetate,泽泻醇A24-醋酸酯 |
Others | Others |
Alisol A 24-acetate (Alisol A monoacetate) 是一种天然产物。 | |||
TQ0195 |
1,5-Anhydrosorbitol
|
Others; Endogenous Metabolite | Metabolism; Others |
1,5-Anhydrosorbitol 是评价短期血糖控制情况的可靠指标,主要来源于食物。 | |||
TN1114 |
Carabrone
|
Antibacterial; Antifection | Microbiology/Virology |
Carabrone 是分离自Carpesium abrotanoides 果实的一种倍半萜,表现出显著抗肿瘤活性和抗菌活性,如灰霉病菌Botrytis cinerea,炭疽病菌Colletotrichum lagenarium 和禾白粉菌Erysiphe graminis。 | |||
T8162 |
Cannabidivarin
Cannabidivarin,GWP-42006,GWP42006,GWP 42006 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Cannabidivarin (GWP42006) 是一种非拟精神病药大麻素。 它具有缓解多种神经系统疾病 (包括癫痫和自闭症谱系障碍) 的研究潜力。 | |||
T5786 |
TETRAHYDROPIPERINE
四氢胡椒碱,Cosmoperine |
P450; TRP/TRPV Channel | Membrane transporter/Ion channel; Metabolism |
Tetrahydropiperine (Cosmoperine) 是胡椒碱的环己基类似物,也是一种天然芳基戊酰胺,从Piper longum 分离得到。它对细胞色素 P450 (CYP) 同工型 CYP1A1/芳基烃羟化酶 (AHH;IC50=23 µM)具有抑制作用。 | |||
T0861 |
Tylosin tartrate
酒石酸泰洛星,酒石酸泰乐菌素 |
Antibacterial; Antibiotic | Microbiology/Virology |
Tylosin tartrate 是一种大环内酯类抗生素,是 Streptomyces fradiae 的产物。它对革兰氏阳性菌具有高效的抗菌活性。它作为饲料添加剂可促进动物生长。它被用于治疗家禽、猪和牛的细菌性痢疾和呼吸道疾病。 | |||
TN1334 |
7-Methoxyrosmanol
7ALPHA-甲氧基迷迭香酚,7-O-Methylrosmanol |
cAMP | GPCR/G Protein |
7-Methoxyrosmanol (7-O-Methylrosmanol) 是一种酚类二萜,从迷迭香中分离得到,可抑制 PEPCK 和 G6Pase 启动子的 cAMP 反应。 | |||
T2O2774 |
L-Asparagine
alpha-aminosuccinamic acid,L-天门冬氨酸,(-)-Asparagine,Asparamide,2-Aminosuccinamic acid,Asn,Altheine |
Endogenous Metabolite | Metabolism |
L-Asparagine (Asparamide) 是一种非必需氨基酸,可以参与神经和脑组织细胞功能的代谢控制。 | |||
T14853 |
Cabergoline
FCE-21336,卡麦角林 |
Dopamine Receptor; 5-HT Receptor; Autophagy | Autophagy; GPCR/G Protein; Neuroscience |
Cabergoline (FCE-21336) 是一种麦角衍生的多巴胺 D2亚类受体激动剂,高亲和力作用于D2、D3和5-HT2B 受体,Ki 分别为 0.7、1.5 和 1.2。 | |||
T3S0195 |
Nootkatone
诺卡酮,努特卡酮,诺卡酮 |
AMPK | Chromatin/Epigenetic; PI3K/Akt/mTOR signaling |
Nootkatone 是一种神经保护剂,来自于Alpiniae OxyphyllaeFructus ,具有抗氧化和抗炎活性。它能够改善脂多糖诱导的阿尔茨海默氏病小鼠模型的认知障碍。 | |||
T20754 |
Deltamethrin
Butoss,RU-22974,Esbecythrin,溴氰菊酯,K-Othrin,Decamethrin,RU 22974 |
Others | Others |
Deltamethrin (RU 22974) 是一种具有神经毒性的拟除虫菊酯杀虫剂,在大鼠中能够产生一系列可逆的运动症状(如包括后肢僵硬、舞蹈性关节炎)。 | |||
T4A2462 |
Telocinobufagin
Telobufotoxin,远华蟾蜍精,Telocinobufogenin |
Others | Others |
Telocinobufagin (Telobufotoxin) 是一种从蟾酥中分离提取获得的组份。 | |||
T4592 |
TOMATIDINE HYDROCHLORIDE
Tomatidine,Tomatidine HCl,盐酸番茄碱 |
Others; NF-κB; JNK; Autophagy | Autophagy; MAPK; NF-κB; Others |
Tomatidine hydrochloride (Tomatidine HCl) 是一种甾体生物碱,可防止肌肉萎缩并促进肌肉生长。它通过阻断 NF-κB 和JNK 信号发挥抗炎作用,可激活哺乳动物细胞或秀丽隐杆线虫中的自噬。 | |||
TN1059 |
Ganoderic acid B
|
IL Receptor; HIV Protease; JAK; STAT | Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Proteases/Proteasome; Stem Cells |
Ganoderic acid B 是从灵芝中分离的一种三萜类天然产物。它是端粒酶抑制剂,抑制 Epstein-Barr 病毒抗原的活化。它是 HIV-1 蛋白酶抑制剂。 | |||
T1157 |
Moxidectin
milbemycin B,CL301423,莫昔克丁,莫西菌素 |
GluCls; Antibiotic; Parasite | Microbiology/Virology |
Moxidectin (CL301423) 是可用于预防和控制心丝虫和蛔虫的一种驱虫剂。 | |||
TN3048 |
4-Methoxycinnamaldehyde
p-Methoxycinnamaldehyde |
RSV | Microbiology/Virology |
4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde) 是 Agastache rugosa 的一种活性成分。4-Methoxycinnamaldehyde 对人喉癌细胞系中的呼吸道合胞病毒 (RSV) 具有细胞保护活性,有助于控制 RSV 感染诱发的疾病,IC50 约为 0.055 μg/mL。 | |||
T20945 |
2,4-D
Hedonal,Macondray,2,4-D acid,Chloroxone,2,4-二氯苯氧乙酸 |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
2,4-Dichlorophenoxyacetic acid (Hedonal) 是一种合成生长素,用作植物生长调节剂,也用作植物细胞培养基中的补充剂。它是除草剂中的一种活性成分,用于破坏肌动蛋白细胞骨架,以控制根系伸长和细胞生成。 | |||
T6S0232 |
Eriodictyol
圣草酚,Huazhongilexone |
Influenza Virus; DNA/RNA Synthesis; Nrf2; Endogenous Metabolite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology |
Eriodictyol (Huazhongilexone) 是从中草药中得到的一种黄酮类天然产物,具有抗氧化、抗炎和抗糖尿病作用。它还是一种流感依赖 RNA 的RNA 聚合酶抑制剂,IC50为 18 nM。它可诱导Nrf2信号通路。 | |||
T6S1653 |
Albiflorin
Alibiflorin,芍药内酯苷 |
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
Albiflorin (Alibiflorin) 是一种牡丹根中的主要成分,是一种单萜糖苷。它具有神经保护、抗炎、抗氧化和缓解疼痛作用。 | |||
T0414 |
D-Mannitol
Mannite,Mannitol,D-甘露糖醇,Osmitrol |
Apoptosis; Dehydrogenase; Endogenous Metabolite | Apoptosis; Metabolism |
D-Mannitol (Mannitol) 是与山梨醇相关的利尿剂和肾脏诊断辅助剂,具有较弱的肾脏血管扩张活性。 | |||
T64744 |
Ovalbumins
|
Endogenous Metabolite | Metabolism |
Ovalbumins 是蛋清中的主要蛋白质。Ovalbumins 具有多种生物活性,如降压、抗菌、抗癌、抗氧化和免疫调节活性。Ovalbumins 是雌激素或孕酮处理的输卵管中合成的丰富的蛋白质。Ovalbumins 通常用作研究激素控制该组织中基因表达的标志物。 | |||
T3926 |
Echinatin
刺甘草查尔酮,Retrochalcone |
Free radical scavengers | oxidation-reduction |
Echinatin (Retrochalcone) 是分离自中草药甘草中,具有保肝和抗炎活性。在大鼠中,它可以被快速吸收和消除,并广泛分布,绝对生物利用度约为 6.81%。 | |||
T3891 |
Oroxylin A-7-O-glucuronide
Oroxylin A Glucoronide,千层纸素A-7-0-Β-D-葡萄糖醛酸苷,Oroxyloside,Oroxylin A 7-O-beta-D-glucuronide |
Others | Others |
Oroxylin A-7-O-glucuronide (Oroxylin A Glucoronide) 是一种类黄酮葡糖苷酸,提取自 Scutellaria baicalensis 干燥的根中,具有脯氨酰寡肽酶(POP)抑制作用。 | |||
T2915 |
Bardoxolone
RTA 401,齐墩果烷三萜化合物,CDDO |
Others; Nrf2 | Immunology/Inflammation; Others |
Bardoxolone (CDDO) 是新型核调节因子激活剂。 | |||
T8270 |
Deserpidine
地舍平,Harmonyl |
RAAS | Endocrinology/Hormones |
Deserpidine (Harmonyl) 是从 Rauwolfia canescens 的根中分离的生物碱。Deserpidine 与 Reserpine 相关。Deserpidine 是竞争性血管紧张素转化酶抑制剂,可以被用作抗高血压药以及镇定剂。Deserpidine 还减少了肾上腺皮质血管紧张素 II 诱导的醛固酮分泌。 | |||
TN2635 | 15-Demethylplumieride | Others | Others |
15-Demethylplumieride is a quality control index of Plumeriarubra L. | |||
T23825 | Bryononic acid | ||
Bryononic acid is a new cucurbitane-type triterpenoid. Bryonolic acid transcriptional control of anti-inflammatory and antioxidant genes in macrophages in vitro and in vivo. | |||
TN1024 |
Baldrinal
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Others | Others |
Baldrinal, valtrate, and acevaltrate are the quality control compounds of Valeriana jatamansi Jones. | |||
TN6564 |
Palustrol
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Palustrol exhibits acaricidal, insecticidal, 'pesticidal' and/or arthropod repellent properties, may be useful sources of chemicals for the control of arthropods of medical, veterinary or agricultural importance. | |||
T78499 |
1,5-Anhydro-D-mannitol
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1,5-Anhydro-D-mannitol为1,5-Anhydrosorbitol的非活性类似物,通常用作实验对照。1,5-Anhydrosorbitol则作为评估短期血糖控制的可靠指标。 | |||
TN1479 |
Celosin J
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Others | Others |
Celosin H, celosin I, celosin J could be used as chemical markers for the quality control of C. argentea seeds. | |||
TN3989 |
Erycibelline
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LDL; PPAR | DNA Damage/DNA Repair; Metabolism |
Erycibelline has antiobesity activity, it may be a useful therapeutic agent for body weight control by downregulating adipogenesis and lipogenesis. | |||
T20612 |
4,5,6,7-Tetrachlorophthalide
KF 32,KF32,Rabcide,KF-32,Fthalide |
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4,5,6,7-Tetrachlorophthalide is a fungicide used for the control of rice blast. It has a role as a melanin synthesis inhibitor and an antifungal agrochemical. | |||
TMA0925 | Wilforlide A acetate | Others | Others |
Wilforlide A (T1) serves as a quality control standard of Tripterygium Glycosides that be listed in Drug Standard of Ministry of Public Health of the People's Republic of China. T1 has anti-inflammatory effects. | |||
TN2060 |
Petunidin-3-O-glucoside chloride
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Others | Others |
Petunidin-3-O-glucoside chloride has significantly higher antioxidant activity than the Fe2+ control. Petunidin-3-O-glucoside causes problems in digestibility, may be important dietary supplements with beneficial health effects. | |||
TN3056 | 4-O-Galloylbergenin | Others | Others |
4-O-Galloylbergenin shows significant 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging activity with EC50 7.8 uM, it shows more antioxidant activity than the positive control vitamin C (EC50 = 28.3 uM). | |||
TN1478 |
Celosin I
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Others | Others |
Celosin H, celosin I, and celosin J could be used as chemical markers for the quality control of C. argentea seeds. Celosin I exhibited significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in | |||
TN5463 |
Leachianone G
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Leachianone G exhibits significant antioxidant potentials in the ABTS, ONOO(-), and total ROS assays, it also shows inhibitory activities against pancreatic lipase, it may be used as drug candidate to control obesity. Leachianone G shows potent antiviral | |||
TN5154 | Torilolone | Others | Others |
Torilin and torilolone show hepatoprotective effects on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells,the EC50 values are 20.6 +/- 1.86 and 3.6 +/- 0.1 microM, respectively; and silybin as a positive control shows an EC50 value of 69.0 | |||
TN3626 | Cerbinal | Antifection | Microbiology/Virology |
Cerbinal 是一种天然化合物,来源于非洲非洲菊的草本植物。它具有杀虫活性,是一种潜在的新型害虫防治剂。 | |||
TN4999 | Serratenediol | BCL; PARP; Caspase | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome |
Serratenediol demonstrates strong inhibitory effects on the Epstein-Barr virus early antigen (EBV-EA) activation without showing any cytotoxicity, its effects being stronger than that of a representative control, oleanolic acid. Serratenediol can promote | |||
T82487 |
Ejaponine A
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Ejaponine A(化合物1)为源于日本卫矛的杀虫倍半萜酯。该化合物展现出强效针对粘虫的活性(LD50为89.2 μg/g),在相关杀粘虫机制研究中得到应用。 | |||
TN1606 |
(-)-Epiafzelechin
(-)-表阿夫儿茶精,表阿夫儿茶精 |
COX | Immunology/Inflammation; Neuroscience |
(-)-Epiafzelechin exhibits significant anti-inflammatory activity on carrageenin-induced mouse paw edema, it exhibits a dose-dependent inhibition on the COX activity with an IC50 value of 15 microM, it exhibits about 3-fold weaker inhibitory potency on th | |||
TN2553 |
1-Methyl-2-undecyl-4(1H)-quinolone
1-Methyl-2-undecylquinolin-4(1H)-one |
MAO | Metabolism; Neuroscience |
1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodia rutaecarpa (Juss.) Benth. 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of type B MAO (MAO-B) activity with the IC(50) value of 15.3 microM using a substrate kynuramine, but does not inhibit type A MAO (MAO-A) activity.It can mitigate high phosphate-induced human aortic valve interstitial cells (HAVICs) calcification ... | |||
T35741 |
Gliovirin
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Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum(MIC = 60 ng/ml) and the parasiteT. brucei brucei(IC50= 90 ng/ml), but has no effect on the plant pathogenic fungiR. solani,P. omnivorum,T. basicola,R. arrhizus, andV. dahliaeor the bacteriaB. thuringiensis,P. fluorescens, andX. malvacearumwhen used at concentrations up to 1,000 ng/ml.2,3Gliovirin decrease... | |||
T36563 |
(E)-Guggulsterone
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Bile acids are essential for solubilization and transport of dietary lipids, are the major products of cholesterol catabolism, and are physiological ligands for farnesoid X receptor (FXR), a nuclear receptor that regulates genes involved in lipid metabolism.1They are also inherently cytotoxic, as physiological imbalance contributes to increased oxidative stress.2,3Bile acid-controlled signaling pathways are promising novel targets to treat such metabolic diseases as obesity, type II diabetes, hy... |