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426

抑制剂 & 化合物

46

天然产物

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Cat. No. Product Name Target Signaling Pathways
T38260 SP 600125, negative control

JNK Inhibitor II, negative control

SP 600125, negative control 是 SP 600125 的甲基化类似物,可用作SP 600125的阴性对照,对 DTP3和GADD45β/MKK7(生长停滞和 DNA 损伤诱导型 β/介原活化蛋白激酶激酶 7)具有抑制作用,能够恢复活化。SP 600125, negative control 对 JNK2 和 JNK3 的 IC50s 分别为 18 和 24 μM。
TP1555L1 Fibronectin Active Fragment Control acetate

Fibronectin Active Fragment Control acetate(97461-84-2 Free base)

Fibronectin Active Fragment Control acetate 是纤连蛋白的活性片段,这是一种糖蛋白。
TP1833L SLLK, Control Peptide for TSP1 Inhibitor acetate

SLLK, Control Peptide for TSP1 Inhibitor acetate(464924-27-4,free base)

Others Others
SLLK, Control Peptide for TSP1 Inhibitor acetate(464924-27-4,free base) 是 LSKL 的对照肽。
TP2180L Compstatin control peptide acetate

Complement System Immunology/Inflammation
Compstatin control peptide acetate 是补体蛋白 C3 的抑制剂,通过结合和抑制补体 C3 的切割。
T37559 NF-κB Control

NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α. NF-κB control is a peptide that is identical in sequence to NF-κB inhibitor, except two essential, basic residues of the p105 NLS are substituted with non-basic amino acids...
T39317 ELA-14 negative control

ELA-14 negative control is an inactive peptide that serves as a negative control for ELA-14.
T41227 ARCC 4 negative control

ARCC 4 negative control is a negative control for ARCC 4. Binds androgen receptors (AR) without inducing degradation.
T78337 Mouse IgG2a kappa, Isotype Control

Mouse IgG2a kappa, Isotype Control 是鼠源IIgG2a kappa 抗体的同型抗体。
TP1357 Human IgG1 Control

Human IgG1 Control was purified from Human serum by chromatography.Human IgG1 Control can be used as a Control, standard, blocking agent, or coating protein in a variety of experiments, including ELISA, Western and blotting, immunoprecipitation, and immun
TP2130L Rac1 Inhibitor F56, control peptide acetate

Rac1 Inhibitor F56, control peptide acetate(1315378-77-8 free base)

Rho Cell Cycle/Checkpoint
Rac1 Inhibitor F56, control peptide acetate(1315378-77-8 free base) 是 Rac1 Inhibitor 的对照肽版本;包含Rac1的残基45-60,其中Trp56被Phe 取代。不影响 GEF-Rac1 相互作用。
T36580 Glucagon Receptor Antagonist Inactive Control

Glucagon Receptor Antagonist Inactive Control 是一种 Glucagon 受体拮抗剂,可用于生命科学领域的相关研究。其产品编号为 T36580,CAS号为 362482-00-6。
T36247 TBK1 control PROTAC® 4

Negative control for TBK1 PROTAC 3i. Binds TBK1 with high affinity, but exhibits no significant degradation of TBK1. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
TP1833 SLLK, Control Peptide for TSP1 Inhibitor(TFA)

SLLK, Control Peptide for TSP1 Inhibitor,SLLK,TSP1抑制剂控制肽

SLLK is a control peptide for LSKL.
TP1450 SLLK, Control Peptide for TSP1 Inhibitor(TFA) (464924-27-4 free base)

SLLK, Control Peptide for TSP1 Inhibitor(TFA)

SLLK, Control Peptide for TSP1 Inhibitor (TFA) is a control peptide for LSKL, which is a Thrombospondin (TSP-1) inhibitor.
TP1555 Fibronectin Active Fragment Control

Fibronectin is a high-molecular weight (~440kDa) extracellular matrix glycoprotein that binds to membrane-spanning receptor proteins called integrins.In addition to integrins, fibronectin also binds extracellular matrix components such as collagen, fibrin
TP2130 Rac1 Inhibitor F56, control peptide

Control peptide version of Rac1 Inhibitor; comprises residues 45-60 of Rac1 with Trp56 replaced by Phe. Does not affect GEF-Rac1 interaction.
TP2203 Bax inhibitor peptide, negative control

Others Others
The compound is a negative control peptide for the Bax inhibitor peptides V5 and P5.
TP2039 Dynamin inhibitory peptide, myristoylated (control)

Control peptide version of dynamin inhibitory peptide, myristoylated, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. In contrast to dynamin inhibitory peptide, has no significant eff
T71316 ERK Inhibitor II (Negative control)

ERK InhibitorII (Negative control)为高效的细胞外信号调节激酶(ERK)抑制剂,能抑制胰岛素受体(Insulin Receptor)激活,适用于糖尿病研究。
T41214 (S)-BAY-293

BAY 294,BAY 293 Negative Control

Ras GPCR/G Protein; MAPK
(S)-BAY-293 是一种有效的 pan-KRAS 抑制剂,可用于研究原发性非小肺癌和胰腺癌。
T35059 VinSpinIC

Vinnie's Spindlin Inactive Control,TD020826a

VinSpinIC is an inactive control for VinSpinIn.
T74869 SiRNA Negative Control

SiRNA Negative Control 是 21个核苷酸的 siRNA,可作为阴性对照使用。
T23150 PHGDH-inactive

Others Others
PHGDH-inactive 对 PHGDH 无活性,IC50大于57 μM,可用作 NCT-502 和 NCT-503 的阴性对照。
T81317 Rabbit IgG1 kappa, Isotype Control

RabbitIgG1kappa, Isotype Control为兔源IgG1κ同型对照单克隆抗体,用于科研中作为Rabbit IgG1κ抗体的实验对照。
T78338 Rat IgG1 kappa, Isotype Control

RatIgG1kappa(Isotype Control)是Rat IgG1κ抗体同型对照的鼠源性单克隆抗体。
T78243 Human IgG2 kappa, Isotype Control

HumanIgG2kappa, Isotype Control为人源化单克隆抗体,作为human IgG2κ抗体的标准同型对照使用。
T78244 Human IgG4 kappa, Isotype Control

HumanIgG4kappa Isotype Control为人源化单克隆抗体,用作human IgG4κ抗体的同型对照。
T81756 Mouse IgG3 kappa, Isotype Control

MouseIgG3kappa, Isotype Control为鼠源单克隆抗体,充当mouse IgG3κ抗体的同型对照。
T81757 Mouse IgG2c kappa, Isotype Control

MouseIgG2ckappa, Isotype Control为mouse IgG2cκ同型对照的鼠源单克隆抗体。
T81758 Mouse IgG2b kappa, Isotype Control

MouseIgG2bkappa Isotype Control是mouse IgG2bκ抗体的同型对照,属于鼠源单克隆抗体。
T78336 Mouse IgG1 kappa, Isotype Control

MouseIgG1kappa Isotype Control 为 mouse IgG1κ 抗体的同型对照鼠源单克隆抗体。
T19578 TH-263

Others Others
TH-263 是二芳基磺酰胺衍生物,可用作 TH-257 的阴性对照,对 LIMK1 和 LIMK2 均无抑制活性。
T82157 Human IgG1 lambda1, Isotype Control

HumanIgG1lambda1, Isotype Control为人-鼠嵌合型单克隆抗体,作为human IgG1λ1抗体的同型对照物。
T78242 Human IgG1 kappa, Isotype Control

HumanIgG1kappa, Isotype Control为人源化单克隆抗体,作为human IgG1κ抗体的同型对照物。
T82156 Human IgG3 kappa, Isotype Control

HumanIgG3kappa, Isotype Control为人-鼠嵌合型抗体,作为human IgG3κ抗体同型对照使用。
T15441 GSK8573

Epigenetic Reader Domain Chromatin/Epigenetic
GSK8573 是 GSK2801 的非活性对照化合物。它与BRD9具有结合活性,Kd 值为 1.04 μM。
T78041 Tat-peptide control 168-189 TFA

Tat-peptide 168-189 是一款标记有 Tat 的细胞渗透融合肽,对应回大鼠 G3BP1 的168-189残基。此配合物末端整合了HIV Tat 序列的一个高度非保守部分,以促进其穿透细胞膜。作为Tat-peptide 168-189 TFA的阴性对照,Tat-peptide 168-189 TFA 已被证实可促进轴突生长和增加神经元的突触数目。
T78340 Human IgG1 (N297A) kappa, Isotype Control

HumanIgG1(N297A) kappa, Isotype Control为具有人-鼠嵌合结构的抗体,作为HumanIgG1(N297A)κ 抗体的同型对照物。
T78341 Human IgG1 (F405L) kappa, Isotype Control

HumanIgG1(F405L) kappa, Isotype Control为人-鼠嵌合型单克隆抗体,作为HumanIgG1(F405L)κ抗体的同型对照使用。
T82155 Human IgG4 (S228P) lambda1, Isotype Control

HumanIgG4(S228P) lambda1, Isotype Control,为人-鼠嵌合型抗体,作为humanIgG4(S228P) λ1抗体同型对照使用。
T82161 Human IgG1 (D265A) kappa, Isotype Control

HumanIgG1(D265A) kappa, Isotype Control是一种人鼠嵌合型抗体,用作HumanIgG1(D265A)κ抗体的同型对照。
T81755 Mouse lgG2a (D265A) kappa, Isotype Control

Mouse lgG2a (D265A) kappa, Isotype Control 为 mouse lgG2a (D265A) 的鼠源单克隆同型对照抗体。
T81759 Mouse IgG1 (N297A) kappa, Isotype Control

MouseIgG1(N297A) kappa,Isotype Control 为特定mouse IgG1(N297A)κ 抗体之同型对照,属鼠源单克隆抗体。
T0961 Trometamol

三(羟甲基)氨基甲烷,Tromethamine,缓血酸铵

COX Immunology/Inflammation; Neuroscience
Trometamol (Tromethamine) 是一种在生理范围内控制 pH 值的有效胺类化合物,也是一种低毒性的生物惰性氨基醇,可以在体内和体外缓冲二氧化碳和酸。
T24677 PS47

PS 47,PS-47

PDK PI3K/Akt/mTOR signaling
PS-47(PS 47) 是一种 PS48 的非活性 E-异构体。其中 PS48 是一种 PDK1 的激活剂。PS47 (PS 47) 可用作 PS48 的阴性对照。
T81760 Mouse IgG1 (D265A) kappa, Isotype Control

MouseIgG1(D265A) kappa, Isotype Control 为鼠源IgG1 κ类同型对照单克隆抗体,适用作为mouse IgG1(D265A)κ抗体的实验对照。
T78339 Human IgG4 (S228P) kappa, Isotype Control

HumanIgG4(S228P) kappa, Isotype Control为人-鼠嵌合型单克隆抗体,作为humanIgG4(S228P)κ抗体的同型对照使用。
T82159 Human IgG1 (K214R) kappa, Isotype Control

HumanIgG1(K214R) kappa, Isotype Control为HumanIgG1(K214R)κ 抗体的人源化同型对照,属于人-鼠嵌合型抗体。
T82160 Human IgG1 (D270N) kappa, Isotype Control

HumanIgG1(D270N) kappa, Isotype Control为人-鼠嵌合型抗体, 作为HumanIgG1(D270N)κ 抗体的同型对照品。
T8543 KN-92 hydrochloride

CaMK Neuroscience
KN-92 hydrochloride 是 KN-93 的非活性衍生物,对 CaM 激酶无抑制作用。它可作为对照化合物用于阐明 KN-93 的拮抗活性。KN-93 是一种可渗透细胞的、可逆的、竞争性的 CaMKII 抑制剂。

化合物

SP 600125, negative control
Cat.No: T38260
Synonym: JNK Inhibitor II, negative control
Target:
Fibronectin Active Fragment Control acetate
Cat.No: TP1555L1
Synonym: Fibronectin Active Fragment Control acetate(97461-84-2 Free base)
Target:
SLLK, Control Peptide for TSP1 Inhibitor acetate
Cat.No: TP1833L
Synonym: SLLK, Control Peptide for TSP1 Inhibitor acetate(464924-27-4,free base)
Target: Others
Compstatin control peptide acetate
Cat.No: TP2180L
Synonym:
Target: Complement System
NF-κB Control
Cat.No: T37559
Synonym:
Target:
ELA-14 negative control
Cat.No: T39317
Synonym:
Target:
ARCC 4 negative control
Cat.No: T41227
Synonym:
Target:
Mouse IgG2a kappa, Isotype Control
Cat.No: T78337
Synonym:
Target:
Human IgG1 Control
Cat.No: TP1357
Synonym:
Target:
Rac1 Inhibitor F56, control peptide acetate
Cat.No: TP2130L
Synonym: Rac1 Inhibitor F56, control peptide acetate(1315378-77-8 free base)
Target: Rho
Glucagon Receptor Antagonist Inactive Control
Cat.No: T36580
Synonym:
Target:
TBK1 control PROTAC® 4
Cat.No: T36247
Synonym:
Target:
SLLK, Control Peptide for TSP1 Inhibitor(TFA)
Cat.No: TP1833
Synonym: SLLK, Control Peptide for TSP1 Inhibitor,SLLK,TSP1抑制剂控制肽
Target:
SLLK, Control Peptide for TSP1 Inhibitor(TFA) (464924-27-4 free base)
Cat.No: TP1450
Synonym: SLLK, Control Peptide for TSP1 Inhibitor(TFA)
Target:
Fibronectin Active Fragment Control
Cat.No: TP1555
Synonym:
Target:
Rac1 Inhibitor F56, control peptide
Cat.No: TP2130
Synonym:
Target:
Bax inhibitor peptide, negative control
Cat.No: TP2203
Synonym:
Target: Others
Dynamin inhibitory peptide, myristoylated (control)
Cat.No: TP2039
Synonym:
Target:
ERK Inhibitor II (Negative control)
Cat.No: T71316
Synonym:
Target:
(S)-BAY-293
Cat.No: T41214
Synonym: BAY 294,BAY 293 Negative Control
Target: Ras
VinSpinIC
Cat.No: T35059
Synonym: Vinnie's Spindlin Inactive Control,TD020826a
Target:
SiRNA Negative Control
Cat.No: T74869
Synonym:
Target:
PHGDH-inactive
Cat.No: T23150
Synonym:
Target: Others
Rabbit IgG1 kappa, Isotype Control
Cat.No: T81317
Synonym:
Target:
Rat IgG1 kappa, Isotype Control
Cat.No: T78338
Synonym:
Target:
Human IgG2 kappa, Isotype Control
Cat.No: T78243
Synonym:
Target:
Human IgG4 kappa, Isotype Control
Cat.No: T78244
Synonym:
Target:
Mouse IgG3 kappa, Isotype Control
Cat.No: T81756
Synonym:
Target:
Mouse IgG2c kappa, Isotype Control
Cat.No: T81757
Synonym:
Target:
Mouse IgG2b kappa, Isotype Control
Cat.No: T81758
Synonym:
Target:
Mouse IgG1 kappa, Isotype Control
Cat.No: T78336
Synonym:
Target:
TH-263
Cat.No: T19578
Synonym:
Target: Others
Human IgG1 lambda1, Isotype Control
Cat.No: T82157
Synonym:
Target:
Human IgG1 kappa, Isotype Control
Cat.No: T78242
Synonym:
Target:
Human IgG3 kappa, Isotype Control
Cat.No: T82156
Synonym:
Target:
GSK8573
Cat.No: T15441
Synonym:
Target: Epigenetic Reader Domain
Tat-peptide control 168-189 TFA
Cat.No: T78041
Synonym:
Target:
Human IgG1 (N297A) kappa, Isotype Control
Cat.No: T78340
Synonym:
Target:
Human IgG1 (F405L) kappa, Isotype Control
Cat.No: T78341
Synonym:
Target:
Human IgG4 (S228P) lambda1, Isotype Control
Cat.No: T82155
Synonym:
Target:
Human IgG1 (D265A) kappa, Isotype Control
Cat.No: T82161
Synonym:
Target:
Mouse lgG2a (D265A) kappa, Isotype Control
Cat.No: T81755
Synonym:
Target:
Mouse IgG1 (N297A) kappa, Isotype Control
Cat.No: T81759
Synonym:
Target:
Trometamol
Cat.No: T0961
Synonym: 三(羟甲基)氨基甲烷,Tromethamine,缓血酸铵
Target: COX
PS47
Cat.No: T24677
Synonym: PS 47,PS-47
Target: PDK
Mouse IgG1 (D265A) kappa, Isotype Control
Cat.No: T81760
Synonym:
Target:
Human IgG4 (S228P) kappa, Isotype Control
Cat.No: T78339
Synonym:
Target:
Human IgG1 (K214R) kappa, Isotype Control
Cat.No: T82159
Synonym:
Target:
Human IgG1 (D270N) kappa, Isotype Control
Cat.No: T82160
Synonym:
Target:
KN-92 hydrochloride
Cat.No: T8543
Synonym:
Target: CaMK
Cat. No. Product Name Target Signaling Pathways
T6S2243 Alisol A 24-acetate

Alisol A 24-monoacetate,Alisol A monoacetate,泽泻醇A24-醋酸酯

Others Others
Alisol A 24-acetate (Alisol A monoacetate) 是一种天然产物。
TQ0195 1,5-Anhydrosorbitol

Others; Endogenous Metabolite Metabolism; Others
1,5-Anhydrosorbitol 是评价短期血糖控制情况的可靠指标,主要来源于食物。
TN1114 Carabrone

Antibacterial; Antifection Microbiology/Virology
Carabrone 是分离自Carpesium abrotanoides 果实的一种倍半萜,表现出显著抗肿瘤活性和抗菌活性,如灰霉病菌Botrytis cinerea,炭疽病菌Colletotrichum lagenarium 和禾白粉菌Erysiphe graminis。
T8162 Cannabidivarin

Cannabidivarin,GWP-42006,GWP42006,GWP 42006

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Cannabidivarin (GWP42006) 是一种非拟精神病药大麻素。 它具有缓解多种神经系统疾病 (包括癫痫和自闭症谱系障碍) 的研究潜力。
T5786 TETRAHYDROPIPERINE

四氢胡椒碱,Cosmoperine

P450; TRP/TRPV Channel Membrane transporter/Ion channel; Metabolism
Tetrahydropiperine (Cosmoperine) 是胡椒碱的环己基类似物,也是一种天然芳基戊酰胺,从Piper longum 分离得到。它对细胞色素 P450 (CYP) 同工型 CYP1A1/芳基烃羟化酶 (AHH;IC50=23 µM)具有抑制作用。
T0861 Tylosin tartrate

酒石酸泰洛星,酒石酸泰乐菌素

Antibacterial; Antibiotic Microbiology/Virology
Tylosin tartrate 是一种大环内酯类抗生素,是 Streptomyces fradiae 的产物。它对革兰氏阳性菌具有高效的抗菌活性。它作为饲料添加剂可促进动物生长。它被用于治疗家禽、猪和牛的细菌性痢疾和呼吸道疾病。
TN1334 7-Methoxyrosmanol

7ALPHA-甲氧基迷迭香酚,7-O-Methylrosmanol

cAMP GPCR/G Protein
7-Methoxyrosmanol (7-O-Methylrosmanol) 是一种酚类二萜,从迷迭香中分离得到,可抑制 PEPCK 和 G6Pase 启动子的 cAMP 反应。
T2O2774 L-Asparagine

alpha-aminosuccinamic acid,L-天门冬氨酸,(-)-Asparagine,Asparamide,2-Aminosuccinamic acid,Asn,Altheine

Endogenous Metabolite Metabolism
L-Asparagine (Asparamide) 是一种非必需氨基酸,可以参与神经和脑组织细胞功能的代谢控制。
T14853 Cabergoline

FCE-21336,卡麦角林

Dopamine Receptor; 5-HT Receptor; Autophagy Autophagy; GPCR/G Protein; Neuroscience
Cabergoline (FCE-21336) 是一种麦角衍生的多巴胺 D2亚类受体激动剂,高亲和力作用于D2、D3和5-HT2B 受体,Ki 分别为 0.7、1.5 和 1.2。
T3S0195 Nootkatone

诺卡酮,努特卡酮,诺卡酮

AMPK Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Nootkatone 是一种神经保护剂,来自于Alpiniae OxyphyllaeFructus ,具有抗氧化和抗炎活性。它能够改善脂多糖诱导的阿尔茨海默氏病小鼠模型的认知障碍。
T20754 Deltamethrin

Butoss,RU-22974,Esbecythrin,溴氰菊酯,K-Othrin,Decamethrin,RU 22974

Others Others
Deltamethrin (RU 22974) 是一种具有神经毒性的拟除虫菊酯杀虫剂,在大鼠中能够产生一系列可逆的运动症状(如包括后肢僵硬、舞蹈性关节炎)。
T4A2462 Telocinobufagin

Telobufotoxin,远华蟾蜍精,Telocinobufogenin

Others Others
Telocinobufagin (Telobufotoxin) 是一种从蟾酥中分离提取获得的组份。
T4592 TOMATIDINE HYDROCHLORIDE

Tomatidine,Tomatidine HCl,盐酸番茄碱

Others; NF-κB; JNK; Autophagy Autophagy; MAPK; NF-κB; Others
Tomatidine hydrochloride (Tomatidine HCl) 是一种甾体生物碱,可防止肌肉萎缩并促进肌肉生长。它通过阻断 NF-κB 和JNK 信号发挥抗炎作用,可激活哺乳动物细胞或秀丽隐杆线虫中的自噬。
TN1059 Ganoderic acid B

IL Receptor; HIV Protease; JAK; STAT Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Proteases/Proteasome; Stem Cells
Ganoderic acid B 是从灵芝中分离的一种三萜类天然产物。它是端粒酶抑制剂,抑制 Epstein-Barr 病毒抗原的活化。它是 HIV-1 蛋白酶抑制剂。
T1157 Moxidectin

milbemycin B,CL301423,莫昔克丁,莫西菌素

GluCls; Antibiotic; Parasite Microbiology/Virology
Moxidectin (CL301423) 是可用于预防和控制心丝虫和蛔虫的一种驱虫剂。
TN3048 4-Methoxycinnamaldehyde

p-Methoxycinnamaldehyde

RSV Microbiology/Virology
4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde) 是 Agastache rugosa 的一种活性成分。4-Methoxycinnamaldehyde 对人喉癌细胞系中的呼吸道合胞病毒 (RSV) 具有细胞保护活性,有助于控制 RSV 感染诱发的疾病,IC50 约为 0.055 μg/mL。
T20945 2,4-D

Hedonal,Macondray,2,4-D acid,Chloroxone,2,4-二氯苯氧乙酸

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
2,4-Dichlorophenoxyacetic acid (Hedonal) 是一种合成生长素,用作植物生长调节剂,也用作植物细胞培养基中的补充剂。它是除草剂中的一种活性成分,用于破坏肌动蛋白细胞骨架,以控制根系伸长和细胞生成。
T6S0232 Eriodictyol

圣草酚,Huazhongilexone

Influenza Virus; DNA/RNA Synthesis; Nrf2; Endogenous Metabolite Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology
Eriodictyol (Huazhongilexone) 是从中草药中得到的一种黄酮类天然产物,具有抗氧化、抗炎和抗糖尿病作用。它还是一种流感依赖 RNA 的RNA 聚合酶抑制剂,IC50为 18 nM。它可诱导Nrf2信号通路。
T6S1653 Albiflorin

Alibiflorin,芍药内酯苷

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
Albiflorin (Alibiflorin) 是一种牡丹根中的主要成分,是一种单萜糖苷。它具有神经保护、抗炎、抗氧化和缓解疼痛作用。
T0414 D-Mannitol

Mannite,Mannitol,D-甘露糖醇,Osmitrol

Apoptosis; Dehydrogenase; Endogenous Metabolite Apoptosis; Metabolism
D-Mannitol (Mannitol) 是与山梨醇相关的利尿剂和肾脏诊断辅助剂,具有较弱的肾脏血管扩张活性。
T64744 Ovalbumins

Endogenous Metabolite Metabolism
Ovalbumins 是蛋清中的主要蛋白质。Ovalbumins 具有多种生物活性,如降压、抗菌、抗癌、抗氧化和免疫调节活性。Ovalbumins 是雌激素或孕酮处理的输卵管中合成的丰富的蛋白质。Ovalbumins 通常用作研究激素控制该组织中基因表达的标志物。
T3926 Echinatin

刺甘草查尔酮,Retrochalcone

Free radical scavengers oxidation-reduction
Echinatin (Retrochalcone) 是分离自中草药甘草中,具有保肝和抗炎活性。在大鼠中,它可以被快速吸收和消除,并广泛分布,绝对生物利用度约为 6.81%。
T3891 Oroxylin A-7-O-glucuronide

Oroxylin A Glucoronide,千层纸素A-7-0-Β-D-葡萄糖醛酸苷,Oroxyloside,Oroxylin A 7-O-beta-D-glucuronide

Others Others
Oroxylin A-7-O-glucuronide (Oroxylin A Glucoronide) 是一种类黄酮葡糖苷酸,提取自 Scutellaria baicalensis 干燥的根中,具有脯氨酰寡肽酶(POP)抑制作用。
T2915 Bardoxolone

RTA 401,齐墩果烷三萜化合物,CDDO

Others; Nrf2 Immunology/Inflammation; Others
Bardoxolone (CDDO) 是新型核调节因子激活剂。
T8270 Deserpidine

地舍平,Harmonyl

RAAS Endocrinology/Hormones
Deserpidine (Harmonyl) 是从 Rauwolfia canescens 的根中分离的生物碱。Deserpidine 与 Reserpine 相关。Deserpidine 是竞争性血管紧张素转化酶抑制剂,可以被用作抗高血压药以及镇定剂。Deserpidine 还减少了肾上腺皮质血管紧张素 II 诱导的醛固酮分泌。
TN2635 15-Demethylplumieride

Others Others
15-Demethylplumieride is a quality control index of Plumeriarubra L.
T23825 Bryononic acid

Bryononic acid is a new cucurbitane-type triterpenoid. Bryonolic acid transcriptional control of anti-inflammatory and antioxidant genes in macrophages in vitro and in vivo.
TN1024 Baldrinal

Others Others
Baldrinal, valtrate, and acevaltrate are the quality control compounds of Valeriana jatamansi Jones.
TN6564 Palustrol

Palustrol exhibits acaricidal, insecticidal, 'pesticidal' and/or arthropod repellent properties, may be useful sources of chemicals for the control of arthropods of medical, veterinary or agricultural importance.
T78499 1,5-Anhydro-D-mannitol

1,5-Anhydro-D-mannitol为1,5-Anhydrosorbitol的非活性类似物,通常用作实验对照。1,5-Anhydrosorbitol则作为评估短期血糖控制的可靠指标。
TN1479 Celosin J

Others Others
Celosin H, celosin I, celosin J could be used as chemical markers for the quality control of C. argentea seeds.
TN3989 Erycibelline

LDL; PPAR DNA Damage/DNA Repair; Metabolism
Erycibelline has antiobesity activity, it may be a useful therapeutic agent for body weight control by downregulating adipogenesis and lipogenesis.
T20612 4,5,6,7-Tetrachlorophthalide

KF 32,KF32,Rabcide,KF-32,Fthalide

4,5,6,7-Tetrachlorophthalide is a fungicide used for the control of rice blast. It has a role as a melanin synthesis inhibitor and an antifungal agrochemical.
TMA0925 Wilforlide A acetate

Others Others
Wilforlide A (T1) serves as a quality control standard of Tripterygium Glycosides that be listed in Drug Standard of Ministry of Public Health of the People's Republic of China. T1 has anti-inflammatory effects.
TN2060 Petunidin-3-O-glucoside chloride

Others Others
Petunidin-3-O-glucoside chloride has significantly higher antioxidant activity than the Fe2+ control. Petunidin-3-O-glucoside causes problems in digestibility, may be important dietary supplements with beneficial health effects.
TN3056 4-O-Galloylbergenin

Others Others
4-O-Galloylbergenin shows significant 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging activity with EC50 7.8 uM, it shows more antioxidant activity than the positive control vitamin C (EC50 = 28.3 uM).
TN1478 Celosin I

Others Others
Celosin H, celosin I, and celosin J could be used as chemical markers for the quality control of C. argentea seeds. Celosin I exhibited significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in
TN5463 Leachianone G

Leachianone G exhibits significant antioxidant potentials in the ABTS, ONOO(-), and total ROS assays, it also shows inhibitory activities against pancreatic lipase, it may be used as drug candidate to control obesity. Leachianone G shows potent antiviral
TN5154 Torilolone

Others Others
Torilin and torilolone show hepatoprotective effects on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells,the EC50 values are 20.6 +/- 1.86 and 3.6 +/- 0.1 microM, respectively; and silybin as a positive control shows an EC50 value of 69.0
TN3626 Cerbinal

Antifection Microbiology/Virology
Cerbinal 是一种天然化合物,来源于非洲非洲菊的草本植物。它具有杀虫活性,是一种潜在的新型害虫防治剂。
TN4999 Serratenediol

BCL; PARP; Caspase Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome
Serratenediol demonstrates strong inhibitory effects on the Epstein-Barr virus early antigen (EBV-EA) activation without showing any cytotoxicity, its effects being stronger than that of a representative control, oleanolic acid. Serratenediol can promote
T82487 Ejaponine A

Ejaponine A(化合物1)为源于日本卫矛的杀虫倍半萜酯。该化合物展现出强效针对粘虫的活性(LD50为89.2 μg/g),在相关杀粘虫机制研究中得到应用。
TN1606 (-)-Epiafzelechin

(-)-表阿夫儿茶精,表阿夫儿茶精

COX Immunology/Inflammation; Neuroscience
(-)-Epiafzelechin exhibits significant anti-inflammatory activity on carrageenin-induced mouse paw edema, it exhibits a dose-dependent inhibition on the COX activity with an IC50 value of 15 microM, it exhibits about 3-fold weaker inhibitory potency on th
TN2553 1-Methyl-2-undecyl-4(1H)-quinolone

1-Methyl-2-undecylquinolin-4(1H)-one

MAO Metabolism; Neuroscience
1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodia rutaecarpa (Juss.) Benth. 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of type B MAO (MAO-B) activity with the IC(50) value of 15.3 microM using a substrate kynuramine, but does not inhibit type A MAO (MAO-A) activity.It can mitigate high phosphate-induced human aortic valve interstitial cells (HAVICs) calcification ...
T35741 Gliovirin

Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum(MIC = 60 ng/ml) and the parasiteT. brucei brucei(IC50= 90 ng/ml), but has no effect on the plant pathogenic fungiR. solani,P. omnivorum,T. basicola,R. arrhizus, andV. dahliaeor the bacteriaB. thuringiensis,P. fluorescens, andX. malvacearumwhen used at concentrations up to 1,000 ng/ml.2,3Gliovirin decrease...
T36563 (E)-Guggulsterone

Bile acids are essential for solubilization and transport of dietary lipids, are the major products of cholesterol catabolism, and are physiological ligands for farnesoid X receptor (FXR), a nuclear receptor that regulates genes involved in lipid metabolism.1They are also inherently cytotoxic, as physiological imbalance contributes to increased oxidative stress.2,3Bile acid-controlled signaling pathways are promising novel targets to treat such metabolic diseases as obesity, type II diabetes, hy...

天然产物

Alisol A 24-acetate
Cat.No: T6S2243
Synonym: Alisol A 24-monoacetate,Alisol A monoacetate,泽泻醇A24-醋酸酯
Target: Others
1,5-Anhydrosorbitol
Cat.No: TQ0195
Synonym:
Target: Others, Endogenous Metabolite
Carabrone
Cat.No: TN1114
Synonym:
Target: Antibacterial, Antifection
Cannabidivarin
Cat.No: T8162
Synonym: Cannabidivarin,GWP-42006,GWP42006,GWP 42006
Target: GABA Receptor
TETRAHYDROPIPERINE
Cat.No: T5786
Synonym: 四氢胡椒碱,Cosmoperine
Target: P450, TRP/TRPV Channel
Tylosin tartrate
Cat.No: T0861
Synonym: 酒石酸泰洛星,酒石酸泰乐菌素
Target: Antibacterial, Antibiotic
7-Methoxyrosmanol
Cat.No: TN1334
Synonym: 7ALPHA-甲氧基迷迭香酚,7-O-Methylrosmanol
Target: cAMP
L-Asparagine
Cat.No: T2O2774
Synonym: alpha-aminosuccinamic acid,L-天门冬氨酸,(-)-Asparagine,Asparamide,2-Aminosuccinamic acid,Asn,Altheine
Target: Endogenous Metabolite
Cabergoline
Cat.No: T14853
Synonym: FCE-21336,卡麦角林
Target: Dopamine Receptor, 5-HT Receptor, Autophagy
Nootkatone
Cat.No: T3S0195
Synonym: 诺卡酮,努特卡酮,诺卡酮
Target: AMPK
Deltamethrin
Cat.No: T20754
Synonym: Butoss,RU-22974,Esbecythrin,溴氰菊酯,K-Othrin,Decamethrin,RU 22974
Target: Others
Telocinobufagin
Cat.No: T4A2462
Synonym: Telobufotoxin,远华蟾蜍精,Telocinobufogenin
Target: Others
TOMATIDINE HYDROCHLORIDE
Cat.No: T4592
Synonym: Tomatidine,Tomatidine HCl,盐酸番茄碱
Target: Others, NF-κB, JNK, Autophagy
Ganoderic acid B
Cat.No: TN1059
Synonym:
Target: IL Receptor, HIV Protease, JAK, STAT
Moxidectin
Cat.No: T1157
Synonym: milbemycin B,CL301423,莫昔克丁,莫西菌素
Target: GluCls, Antibiotic, Parasite
4-Methoxycinnamaldehyde
Cat.No: TN3048
Synonym: p-Methoxycinnamaldehyde
Target: RSV
2,4-D
Cat.No: T20945
Synonym: Hedonal,Macondray,2,4-D acid,Chloroxone,2,4-二氯苯氧乙酸
Target: DNA/RNA Synthesis
Eriodictyol
Cat.No: T6S0232
Synonym: 圣草酚,Huazhongilexone
Target: Influenza Virus, DNA/RNA Synthesis, Nrf2, Endogenous Metabolite
Albiflorin
Cat.No: T6S1653
Synonym: Alibiflorin,芍药内酯苷
Target: Reactive Oxygen Species
D-Mannitol
Cat.No: T0414
Synonym: Mannite,Mannitol,D-甘露糖醇,Osmitrol
Target: Apoptosis, Dehydrogenase, Endogenous Metabolite
Ovalbumins
Cat.No: T64744
Synonym:
Target: Endogenous Metabolite
Echinatin
Cat.No: T3926
Synonym: 刺甘草查尔酮,Retrochalcone
Target: Free radical scavengers
Oroxylin A-7-O-glucuronide
Cat.No: T3891
Synonym: Oroxylin A Glucoronide,千层纸素A-7-0-Β-D-葡萄糖醛酸苷,Oroxyloside,Oroxylin A 7-O-beta-D-glucuronide
Target: Others
Bardoxolone
Cat.No: T2915
Synonym: RTA 401,齐墩果烷三萜化合物,CDDO
Target: Others, Nrf2
Deserpidine
Cat.No: T8270
Synonym: 地舍平,Harmonyl
Target: RAAS
15-Demethylplumieride
Cat.No: TN2635
Synonym:
Target: Others
Bryononic acid
Cat.No: T23825
Synonym:
Target:
Baldrinal
Cat.No: TN1024
Synonym:
Target: Others
Palustrol
Cat.No: TN6564
Synonym:
Target:
1,5-Anhydro-D-mannitol
Cat.No: T78499
Synonym:
Target:
Celosin J
Cat.No: TN1479
Synonym:
Target: Others
Erycibelline
Cat.No: TN3989
Synonym:
Target: LDL, PPAR
4,5,6,7-Tetrachlorophthalide
Cat.No: T20612
Synonym: KF 32,KF32,Rabcide,KF-32,Fthalide
Target:
Wilforlide A acetate
Cat.No: TMA0925
Synonym:
Target: Others
Petunidin-3-O-glucoside chloride
Cat.No: TN2060
Synonym:
Target: Others
4-O-Galloylbergenin
Cat.No: TN3056
Synonym:
Target: Others
Celosin I
Cat.No: TN1478
Synonym:
Target: Others
Leachianone G
Cat.No: TN5463
Synonym:
Target:
Torilolone
Cat.No: TN5154
Synonym:
Target: Others
Cerbinal
Cat.No: TN3626
Synonym:
Target: Antifection
Serratenediol
Cat.No: TN4999
Synonym:
Target: BCL, PARP, Caspase
Ejaponine A
Cat.No: T82487
Synonym:
Target:
(-)-Epiafzelechin
Cat.No: TN1606
Synonym: (-)-表阿夫儿茶精,表阿夫儿茶精
Target: COX
1-Methyl-2-undecyl-4(1H)-quinolone
Cat.No: TN2553
Synonym: 1-Methyl-2-undecylquinolin-4(1H)-one
Target: MAO
Gliovirin
Cat.No: T35741
Synonym:
Target:
(E)-Guggulsterone
Cat.No: T36563
Synonym:
Target:
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