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1272

抑制剂 & 化合物

22

天然产物

1

化合物库

64

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Cat. No. Product Name
L1380 转录因子库

695 compounds
695 种转录因子靶向、结构新颖的化合物;

化合物库

转录因子库
Cat.No: L1380
Compounds: 695
Cat. No. Product Name Target Signaling Pathways
T28956 TF-505

FR-146687,FK-687,TF 505,FK687

TF-505, a steroid 5α-reductase inhibitor, is used potentially for the treatment of benign prostatic hyperplasia.
T14665L Motixafortide TFA(664334-36-5,Free)

TF 14016 TFA,BKT140 TFA,BL-8040 TFA,T140 TFA

CXCR Autophagy; GPCR/G Protein; Immunology/Inflammation
Motixafortide TFA(664334-36-5,Free) (BKT140 TFA) 是 CXCR4 的拮抗剂,IC50 为 ~1 nM。它通过改变 miR-15a/16-1 表达下调 ERK、BCL-2、MCL-1 和 cyclin-D1 来诱导 AML 原始细胞凋亡。
T8390 Cefazolin

头孢唑林,头孢唑啉

Others; Antibacterial; Antibiotic Microbiology/Virology; Others
Cefazolin 是一种头孢类抗生素, 用于多种细菌感染的研究。
T14665 Motixafortide

BL-8040,BKT140 (4-fluorobenzoyl),TF14016

CXCR Autophagy; GPCR/G Protein; Immunology/Inflammation
Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM).
T35343 MTI-31

MTI-31,LXI-15029

mTOR PI3K/Akt/mTOR signaling
MTI-31 (LXI-15029) 是口服有效的,高度选择性的mTORC1和mTORC2抑制剂,对 mTOR 的Kd 为 0.20 nM,IC50为 39 nM。MTI-31可用于乳腺癌的研究。
T80168 Scorpion toxin Tf2

Sodium Channel Membrane transporter/Ion channel
Scorpion toxin Tf2为一种在Tityus fasciolatus的毒液中首次发现的β-蝎毒素。作为Nav1.3激活剂,该毒素与神经元的电压门控钠(Nav)亚型相关,此亚型与癫痫和伤害感受密切相关。Scorpion toxin Tf2作用于hNav1.3,能够增强其激活电压,并且能够在静息膜电位下开启该通道。
T0953 Cefazolin sodium

Ancef,头孢唑啉钠,头孢唑林钠,Cefazolin sodium salt,Sodium cephazolin,cephazolin sodium,cefazoline sodium,Sodium cefazolin

Others; Antibacterial; Antibiotic Microbiology/Virology; Others
Cefazolin sodium (cephazolin sodium) salt 是一种头孢类抗生素, 可研究多种细菌感染。
T64341 H-β-Ala-AMC TFA

Others Others
H-β-Ala-AMC TFA 是氨基肽酶的底物之一。
T76251L Ac-FEID-CMK TFA

Pyroptosis Apoptosis; Immunology/Inflammation
Ac-FEID-CMK TFA 是一种选择性斑马鱼 GSDMEb 衍生肽抑制剂,可减少感染性休克的死亡率和肾损伤。Ac-FEID-CMK TFA 在体内可抑制焦亡,缓解败血性 AKI (急性肾损伤),抑制 caspy2 介导的非典型炎症小体通路发挥作用。
TP1622 DX600 TFA

RAAS Endocrinology/Hormones
DX600 TFA 是 ACE2 的特异性抑制剂,不会与 ACE 发生交叉反应。
TP2036L DPDPE TFA (88373-73-3 free base)

DPDPE TFA

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
DPDPE TFA 是选择性 δ-阿片受体激动剂肽,在体内具有镇痛作用。
T1351 H-Lys(Tfa)-OH

Amino Acids and Derivatives Metabolism
H-Lys(Tfa)-OH 是L-lysine cyclodeaminase 的抑制剂。
T4470 Pyridostatin TFA

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Pyridostatin TFA 是一种 G-四链体稳定剂,靶向原癌基因 Src,降低人乳腺癌细胞 SRC 蛋白水平和 SRC 依赖的细胞运动。它通过诱导复制和转录依赖的 DNA 损伤促进人类癌细胞生长停滞。
T7759 Thalidomide-O-amido-C4-NH2 TFA

E3 ligase Ligand-Linker Conjugates 19 TFA,Cereblon Ligand-Linker Conjugates 6 TFA

E3 Ligase Ligand-Linker Conjugate PROTAC
Thalidomide-O-amido-C4-NH2 TFA (E3 ligase Ligand-Linker Conjugates 19 TFA) 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker,是一种合成的 E3 连接酶配体-linker 偶联物。
T35499 β-Amyloid (1-42), (rat/mouse) (TFA)

Amyloid β-peptide (1-42) (human) TFA,166090-74-0 TFA

β-Amyloid (1-42), (rat/mouse) (TFA) 是由 42 个氨基酸组成的多肽片段,可用于研究阿尔茨海默症。
T73712 Metformin-d6 hydrochloride

1,1-Dimethylbiguanide-d6 hydrochloride

AMPK; Autophagy Autophagy; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) 是 Metformin 的一种氘代化物,可用于研究 Metformin 在体内的代谢,常作为Metformin的内标。
T2363 STF-31

transporter; Autophagy Autophagy; Metabolism
STF31 是一种葡萄糖转运蛋白 1 的选择性抑制剂,IC50为 1 μM。
T8768 MM-102 TFA

HMTase Inhibitor IX TFA

Histone Methyltransferase Chromatin/Epigenetic
MM-102 TFA (HMTase Inhibitor IX TFA) 是一种有效的 WDR5/MLL 相互作用抑制剂,在 WDR5 结合检测中,IC50为 2.4 nM,Ki 小于 1 nM。
T8526 Metformin

甲福明,二甲双胍,1,1-Dimethylbiguanide

Mitophagy; AMPK; Autophagy Autophagy; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Metformin (1,1-Dimethylbiguanide) 是一种 AMPK 激活剂,具有血脑屏障渗透性。Metformin 可通过提高胰岛素敏感性和减少肠道对葡萄糖的吸收来改善血糖控制,常用于 2 型糖尿病的研究。
T7326 6H05 (TFA)

6H05 TFA,6H05 trifluoroacetate

Ras GPCR/G Protein; MAPK
6H05 TFA (6H05 trifluoroacetate) 是一种选择性变构致癌突变体 K-Ras(G12C) 抑制剂。
T7665 [Leu5]-Enkephalin TFA(58822-25-6(free bas))

Leu-enkephalin,Leucine enkephalin,Leucyl-enkephalin

Opioid Receptor; Endogenous Metabolite Endocrinology/Hormones; GPCR/G Protein; Metabolism; Neuroscience
[Leu5]-Enkephalin TFA(58822-25-6(free bas)) (Leucyl-enkephalin) 是最有效的 δ 受体。
T11237L Camizestrant TFA

Camizestrant TFA(2222844-89-3 Free base),AZD-9833 TFA

Estrogen Receptor/ERR Endocrinology/Hormones
Camizestrant TFA (AZD-9833 TFA) 是一种有效的口服雌激素受体拮抗剂。
T30191L Atecegatran TFA

Atecegatran TFA(917904-13-3 Free base),AR-H067637 TFA

Others Others
Atecegatran TFA 常被当作一种抗凝血剂,可用来治疗心血管疾病。
TP1793L Nociceptin (1-13) amide TFA

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
Nociceptin (1-13) amide TFA (178064-02-3 free base) 是一种有效的 Opioid receptor-like1 (ORL1) receptor 激动剂,对小鼠输精管的 pEC50 为 7.9,与大鼠前脑膜结合的 Ki 为 0.75 nM。
TP1904L FSLLRY-NH2 TFA(245329-02-6 free base)

Protease-activated Receptor GPCR/G Protein
FSLLRY-NH2 TFA(245329-02-6 free base) 是一种蛋白酶激活受体 2 (PAR2) 抑制剂。在 ICR 小鼠中逆转紫杉醇诱导的机械异常性疼痛、热痛觉过敏和 PKC 激活。阻断分离的心脏成纤维细胞中的 ERK 活化和胶原蛋白生成。还可以减轻皮肤癣菌相关瘙痒小鼠模型的症状。
TP1086 Men 10376 TFA(135306-85-3,free)

Men 10376 TFA,Neurokinin-2 receptor antagonist TFA

Neurokinin receptor GPCR/G Protein; Neuroscience
Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) 是一种有效的选择性速激肽 nk-2 受体拮抗剂,对大鼠小肠 nk-2 受体的 K I 值为 4.4 M。
TP1216 CaM kinase II inhibitor TFA salt

Autocamtide-2-related inhibitory peptide (TFA)

CaMK Neuroscience
CaM kinase II inhibitor TFA salt (Autocamtide-2-related inhibitory peptide(TFA)) 是一种高度特异性和有效的 CaMKII 抑制剂,IC50 为 40 nM。
T23233L RETF-4NA acetate

RETF-4NA acetate(1160928-63-1 free base)

Others Others
RETF-4NA acetate 是一种敏感的、特异性的糜蛋白酶底物。
T7617L Neurotensin(8-13) 3TFA(60482-95-3(free base))

Neurotensin Receptor GPCR/G Protein
Neurotensin(8-13) 3TFA(60482-95-3(free base)) 是神经降压素 (NT) 片段,神经降压素 (8-13) 导致细胞表面 NT1 受体 (NTR1) 密度降低。
TP1605L1 Allatostatin IV TFA(123338-13-6 free base)

Others Others
Allatostatin IV TFA(123338-13-6 free base) 是一种八肽胺,是在昆虫中发现的抑制(allatostatins)或刺激(allatotropins)保幼激素(JH)合成的调节肽家族的成员。
TP1351L Kemptide TFA

Others Others
Kemptide TFA (65189-71-1 free base) 是一种合成七肽,可作为 cAMP 依赖性蛋白激酶 (PK) 的底物。
T22774L eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA)

Others Others
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) 是延伸因子 1 亚基。真核翻译延伸因子 1 alpha 1 (EEF1A1) 编码延伸因子 alpha 亚基的同种型- 1 复合物,负责将氨酰 tRNA 酶促递送至核糖体。这种亚型(α 1)在脑、胎盘、肺、肝、肾和胰腺中表达,另一种亚型(α 2)在脑、心脏和骨骼肌中表达。这种亚型在 66% 的 Felty 综合征患者中被鉴定为自身抗原。已发现该基因在许多染色体上具有多个拷贝,其中一些(如果不是全部)代表不同的假基因。
T7627L Adrenocorticotropic Hormone (ACTH) (4-10) TFA

Adrenocorticotropic Hormone (ACTH) (4-10) TFA(4037-01-8(free base)),Acth (4-10)

Melanocortin Receptor GPCR/G Protein; Neuroscience
Adrenocorticotropic Hormone (ACTH) (4-10) TFA (Acth (4-10)) 是一种有效的黑皮质素 (MC4R) 受体激动剂。
TP1918L Lys-[Des-Arg9]Bradykinin,TFA

Lys-[Des-Arg9]Bradykinin,TFA 71800-36-7(fb-tfa)

Bradykinin Receptor GPCR/G Protein
Lys-[Des-Arg9]Bradykinin,TFA (71800-36-7 free base) 是内源性强效和高选择性的缓激肽 B1 受体激动剂(对人 B1 和 B2 受体的 Ki 值分别为 0.12 和 > 30000 nM)。降低体内外周血管阻力的降压药。比 [Des-Arg9]-缓激肽强 16 倍。
T7566L GRGDSPK 2TFA(111119-28-9(free base))

EMD 56574

Others Others
GRGDSPK 2TFA(111119-28-9(free base)) (EMD 56574) 是一种抑制肽,用于 RGD 介导的整合素和细胞外基质分子之间的粘附。
T4021L UNC3866 TFA(1872382-47-2 free base)

Histone Methyltransferase Chromatin/Epigenetic
UNC3866 TFA(1872382-47-2 free base) 是由 AlphaScreen 确定的 CBX7-H3 相互作用的有效拮抗剂。
T7484L WKYMVM 2TFA(187986-17-0(free base))

Others Others
WKYMVM 2TFA(187986-17-0(free base)) 是一种 N-甲酰肽受体 (FPR1) 激动剂。
TP1318 Antennapedia Peptide TFA(188842-14-0 free base)

Antennapedia Peptide(TFA)

Others Others
Antennapedia Peptide TFA (188842-14-0 free base) 是一种 16 个氨基酸的肽,是细胞穿透肽家族的成员,最初来源于果蝇转录因子 Antennapedia 的 60 个氨基酸长的同源域。
T7663L Angiotensin 1/2 (1-9) TFA(34273-12-6(free base))

Others Others
Angiotensin 1/2 (1-9) TFA(34273-12-6(free base)) 含有从血管紧张素 I/II 肽转化而来的氨基酸 1-9。
T8559 Galnon TFA(475115-35-6(free base))

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
GALNON TFA(475115-35-6(free base)) 是一种新型非肽甘丙肽受体激动剂(GAL1 和 GAL2,Ki 分别为 11.7 和 34.1 μM)。
T7758 Thalidomide-O-amido-PEG3-C2-NH2 TFA

E3 ligase Ligand-Linker Conjugates 14 TFA,Cereblon Ligand-Linker Conjugates 3 (TFA)

Others; E3 Ligase Ligand-Linker Conjugate; Ligand for E3 Ligase Others; PROTAC
Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) 包含基于 Thalidomide 的 cereblon 配体和 3 个单元的 PEG linker,是一种合成的 E3 连接酶配体-linker 偶联物。
T17918 Thalidomide-O-amido-PEG2-C2-NH2 TFA

E3 Ligase Ligand-Linker Conjugates 24 TFA,Cereblon Ligand-Linker Conjugates 10 TFA

Others; E3 Ligase Ligand-Linker Conjugate Others; PROTAC
Thalidomide-O-amido-PEG2-C2-NH2 TFA (E3 Ligase Ligand-Linker Conjugates 24 TFA) 包含基于 Thalidomide 的 cereblon 配体和 2 个单元的 PEG linker,是一种合成的 E3 连接酶配体-linker 偶联物。
T21083 TFIIH Modulator-19

TFIIH Modulator19,TFIIH Modulator 19

Others Others
TFIIH Modulator-19 诱导毛发硫营养不良组 A 蛋白的二聚化以调节 TFIIH 转录活性。
TP1346 CYN 154806 TFA

CYN 154806 TFA

Somatostatin GPCR/G Protein
CYN 154806 TFA(183658-72-2 free base) 是一种环状八肽,是一种有效的选择性生长抑素 sst2 受体拮抗剂。对于重组 sst2、sst1、sst3、sst4 和 sst5 受体,pIC50 值分别为 8.58、5.41、6.07、5.76 和 6.48。
T76089 Pepinh-TRIF TFA

Raf; TLR Immunology/Inflammation; MAPK
Pepinh-TRIF TFA 是一种 30 aa 肽,与免疫系统有关,通过干扰 TLR-TRIF 的相互作用 (TLR-TRIF interaction ) 来阻断 TRIF 信号。
TP1388 HAEGTFTSDVSSYLE

Others Others
HAEGTFTSDVSSYLE 是一种多肽。GLP-1 类似物包含该序列。
TP1300 GsMTx4 TFA (1209500-46-8 free base)

GsMTx4 TFA

Piezo Channel Membrane transporter/Ion channel
GsMTx4 TFA (1209500-46-8 free base) (GsMTx4 TFA) 是一种蜘蛛毒肽,可选择性地抑制属于 Piezo 和 TRP 通道家族的阳离子可渗透机械敏感通道 (MSC)。
T69735 ITF3756

HDAC Chromatin/Epigenetic; DNA Damage/DNA Repair
ITF3756 是一种选择性 HDAC6 抑制剂。
T13604 CDDO-dhTFEA

Others; NF-κB; Nrf2 Immunology/Inflammation; NF-κB; Others
CDDO-dhTFEA 是合成的齐墩果烷三萜化合物,可有效激活Nrf2并抑制促炎转录因子NF-κB。 它可以恢复高血压 (MAP),提高 Nrf2 及其靶基因的表达,抑制 NF-κB 的活化和转化生长因子-β 途径,并减少慢性肾病 (CKD) 大鼠的肾小球硬化,间质纤维化和炎症。
T8552 PSEM 89S TFA

AChR Neuroscience
PSEM 89S TFA 是一种脑渗透性和选择性离子通道激动剂,分别对 Q79G 和 L141F 具有正交选择性。

化合物

TF-505
Cat.No: T28956
Synonym: FR-146687,FK-687,TF 505,FK687
Target:
Motixafortide TFA(664334-36-5,Free)
Cat.No: T14665L
Synonym: TF 14016 TFA,BKT140 TFA,BL-8040 TFA,T140 TFA
Target: CXCR
Cefazolin
Cat.No: T8390
Synonym: 头孢唑林,头孢唑啉
Target: Others, Antibacterial, Antibiotic
Motixafortide
Cat.No: T14665
Synonym: BL-8040,BKT140 (4-fluorobenzoyl),TF14016
Target: CXCR
MTI-31
Cat.No: T35343
Synonym: MTI-31,LXI-15029
Target: mTOR
Scorpion toxin Tf2
Cat.No: T80168
Synonym:
Target: Sodium Channel
Cefazolin sodium
Cat.No: T0953
Synonym: Ancef,头孢唑啉钠,头孢唑林钠,Cefazolin sodium salt,Sodium cephazolin,cephazolin sodium,cefazoline sodium,Sodium cefazolin
Target: Others, Antibacterial, Antibiotic
H-β-Ala-AMC TFA
Cat.No: T64341
Synonym:
Target: Others
Ac-FEID-CMK TFA
Cat.No: T76251L
Synonym:
Target: Pyroptosis
DX600 TFA
Cat.No: TP1622
Synonym:
Target: RAAS
DPDPE TFA (88373-73-3 free base)
Cat.No: TP2036L
Synonym: DPDPE TFA
Target: Opioid Receptor
H-Lys(Tfa)-OH
Cat.No: T1351
Synonym:
Target: Amino Acids and Derivatives
Pyridostatin TFA
Cat.No: T4470
Synonym:
Target: DNA/RNA Synthesis
Thalidomide-O-amido-C4-NH2 TFA
Cat.No: T7759
Synonym: E3 ligase Ligand-Linker Conjugates 19 TFA,Cereblon Ligand-Linker Conjugates 6 TFA
Target: E3 Ligase Ligand-Linker Conjugate
β-Amyloid (1-42), (rat/mouse) (TFA)
Cat.No: T35499
Synonym: Amyloid β-peptide (1-42) (human) TFA,166090-74-0 TFA
Target:
Metformin-d6 hydrochloride
Cat.No: T73712
Synonym: 1,1-Dimethylbiguanide-d6 hydrochloride
Target: AMPK, Autophagy
STF-31
Cat.No: T2363
Synonym:
Target: transporter, Autophagy
MM-102 TFA
Cat.No: T8768
Synonym: HMTase Inhibitor IX TFA
Target: Histone Methyltransferase
Metformin
Cat.No: T8526
Synonym: 甲福明,二甲双胍,1,1-Dimethylbiguanide
Target: Mitophagy, AMPK, Autophagy
6H05 (TFA)
Cat.No: T7326
Synonym: 6H05 TFA,6H05 trifluoroacetate
Target: Ras
[Leu5]-Enkephalin TFA(58822-25-6(free bas))
Cat.No: T7665
Synonym: Leu-enkephalin,Leucine enkephalin,Leucyl-enkephalin
Target: Opioid Receptor, Endogenous Metabolite
Camizestrant TFA
Cat.No: T11237L
Synonym: Camizestrant TFA(2222844-89-3 Free base),AZD-9833 TFA
Target: Estrogen Receptor/ERR
Atecegatran TFA
Cat.No: T30191L
Synonym: Atecegatran TFA(917904-13-3 Free base),AR-H067637 TFA
Target: Others
Nociceptin (1-13) amide TFA
Cat.No: TP1793L
Synonym:
Target: Opioid Receptor
FSLLRY-NH2 TFA(245329-02-6 free base)
Cat.No: TP1904L
Synonym:
Target: Protease-activated Receptor
Men 10376 TFA(135306-85-3,free)
Cat.No: TP1086
Synonym: Men 10376 TFA,Neurokinin-2 receptor antagonist TFA
Target: Neurokinin receptor
CaM kinase II inhibitor TFA salt
Cat.No: TP1216
Synonym: Autocamtide-2-related inhibitory peptide (TFA)
Target: CaMK
RETF-4NA acetate
Cat.No: T23233L
Synonym: RETF-4NA acetate(1160928-63-1 free base)
Target: Others
Neurotensin(8-13) 3TFA(60482-95-3(free base))
Cat.No: T7617L
Synonym:
Target: Neurotensin Receptor
Allatostatin IV TFA(123338-13-6 free base)
Cat.No: TP1605L1
Synonym:
Target: Others
Kemptide TFA
Cat.No: TP1351L
Synonym:
Target: Others
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA)
Cat.No: T22774L
Synonym:
Target: Others
Adrenocorticotropic Hormone (ACTH) (4-10) TFA
Cat.No: T7627L
Synonym: Adrenocorticotropic Hormone (ACTH) (4-10) TFA(4037-01-8(free base)),Acth (4-10)
Target: Melanocortin Receptor
Lys-[Des-Arg9]Bradykinin,TFA
Cat.No: TP1918L
Synonym: Lys-[Des-Arg9]Bradykinin,TFA 71800-36-7(fb-tfa)
Target: Bradykinin Receptor
GRGDSPK 2TFA(111119-28-9(free base))
Cat.No: T7566L
Synonym: EMD 56574
Target: Others
UNC3866 TFA(1872382-47-2 free base)
Cat.No: T4021L
Synonym:
Target: Histone Methyltransferase
WKYMVM 2TFA(187986-17-0(free base))
Cat.No: T7484L
Synonym:
Target: Others
Antennapedia Peptide TFA(188842-14-0 free base)
Cat.No: TP1318
Synonym: Antennapedia Peptide(TFA)
Target: Others
Angiotensin 1/2 (1-9) TFA(34273-12-6(free base))
Cat.No: T7663L
Synonym:
Target: Others
Galnon TFA(475115-35-6(free base))
Cat.No: T8559
Synonym:
Target: Neuropeptide Y Receptor
Thalidomide-O-amido-PEG3-C2-NH2 TFA
Cat.No: T7758
Synonym: E3 ligase Ligand-Linker Conjugates 14 TFA,Cereblon Ligand-Linker Conjugates 3 (TFA)
Target: Others, E3 Ligase Ligand-Linker Conjugate, Ligand for E3 Ligase
Thalidomide-O-amido-PEG2-C2-NH2 TFA
Cat.No: T17918
Synonym: E3 Ligase Ligand-Linker Conjugates 24 TFA,Cereblon Ligand-Linker Conjugates 10 TFA
Target: Others, E3 Ligase Ligand-Linker Conjugate
TFIIH Modulator-19
Cat.No: T21083
Synonym: TFIIH Modulator19,TFIIH Modulator 19
Target: Others
CYN 154806 TFA
Cat.No: TP1346
Synonym: CYN 154806 TFA
Target: Somatostatin
Pepinh-TRIF TFA
Cat.No: T76089
Synonym:
Target: Raf, TLR
HAEGTFTSDVSSYLE
Cat.No: TP1388
Synonym:
Target: Others
GsMTx4 TFA (1209500-46-8 free base)
Cat.No: TP1300
Synonym: GsMTx4 TFA
Target: Piezo Channel
ITF3756
Cat.No: T69735
Synonym:
Target: HDAC
CDDO-dhTFEA
Cat.No: T13604
Synonym:
Target: Others, NF-κB, Nrf2
PSEM 89S TFA
Cat.No: T8552
Synonym:
Target: AChR
Cat. No. Product Name Target Signaling Pathways
T81001 TF-DG-cThea

TF-DG-cThea是一种与红茶储存相关的标志性化合物。
T81002 TF-3ʹ-G-cThea

TF-3ʹ-G-cThea是一种与红茶存储过程相关联的标志性化学物质。
T81003 TF-3-G-cThea

TF-3-G-cThea是与红茶储存过程相关的重要标志化合物。
T5429 Theaflavin 3,3'-digallate

茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG

Virus Protease; Antioxidant; HIV Protease; HSV Microbiology/Virology; oxidation-reduction; Proteases/Proteasome
Theaflavin 3,3'-digallate (8-Gingerol) 是一种寨卡病毒蛋白酶抑制剂,IC50为 2.3 μM。它直接与 ZIKVpro 结合并抑制 ZIKV 复制,可抑制 gp41 和 NS2B-3 蛋白酶的活性,并具有抗 HSV 和 HIV-1病毒活性。它是红茶中的主要多酚,有抗肿瘤作用。
T4643 TFAP

N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide

COX; Endogenous Metabolite Immunology/Inflammation; Metabolism; Neuroscience
TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) 是环氧酶 1 的一种选择性抑制剂,IC50值为 0.8 μM。
T36295 Echistatin TFA

Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of αIIbβ3, αvβ3 and α5β1[1][2][3][4]. [1]. J Musial, et al. Inhibition of platelet adhesion to surfaces of extracorporeal circuits by disintegrins. RGD-containing peptides from viper venoms. Circulation. 1990 Jul;82(1):261-73.[2]. ...
T75753 Magainin 1 TFA

Magainin 1 TFA (Magainin I TFA) 是从 Xenopus laevis 皮肤中分离出的一种抗菌和两亲性肽。Magainin 1 TFA 对多种革兰氏阴性和革兰氏阳性细菌均表现出抗生素活性。
T75722 Chlorotoxin TFA

Chlorotoxin TFA,一种从蝎子毒液中分离出的多肽,作为氯离子通道 (chloride channel) 的阻断剂,具备抗癌活性。
T75974 Cecropin A TFA

Cecropin A TFA 是由 37 个氨基酸残基构成的线性抗菌肽,从 Hyalaphora cecropiapupae 得到,具有抗菌、抗炎和抗癌作用。
T75890 Conantokin G TFA

Conantokin G TFA 是一种 17 个氨基酸的肽,是一种有效,选择性和竞争性的 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂。Conantokin G TFA 抑制鼠皮质神经元中NMDA 诱发的电流,IC50为 480 nM,具有神经保护作用。
T83693 Magainin 2 TFA

MG2

Magainin 2是一种从非洲爪蟾(X. laevis)皮肤中分离出的阳离子肽,具有宿主防御和抗菌活性。该化合物对细菌E. coli、K. pneumoniae、S. epidermidis、S. aureus及真菌C. albicans表现出活性(MICs分别为5、10、10、50和80 µg/ml)。Magainin 2(20 µM)能降低猕猴桃花粉的萌发率和平均管长。在被单纯疱疹病毒1型(HSV-1)或2型(HSV-2)感染的Vero细胞中,它可减少病毒复制(EC50s分别为22.16和19.8 µM),同时不影响细胞活性,其50%细胞毒性浓度值(CC50)大于100 µM。
T73764 L-Palmitoylcarnitine TFA

L-Palmitoylcarnitine TFA 是一种长链酰基肉碱和脂肪酸代谢产物,在缺血期间积聚于肌膜并扰乱膜脂环境。L-Palmitoylcarnitine TFA 通过与Kir6.2的相互作用抑制KATP 通道活性,而不影响单通道电导。
T35401 γ-Glu-Gly TFA

γ-Glu-Gly TFA, a γ-glutamyl dipeptide, is a human lipid metabolite with a structure resembling GABA (γ-aminobutyric acid). It serves as an excitatory amino acid antagonist [1][2][3].
T61171 Cyclo(his-pro) TFA

Cyclo(his-pro) TFA, an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone, has shown inhibitory effects on NF-κB nuclear accumulation. Additionally, it possesses the ability to cross the blood-brain barrier and impact various inflammatory and stress responses [1, 2].
T75743 HA Peptide TFA

HA Peptide (TFA) 为源自人类流感血凝素 (HA) 的九氨基酸多肽, 在细胞生物学与生物化学领域内广泛应用于目标蛋白的分离、纯化、检测及追踪。
T78500 α-Factor Mating Pheromone, yeast TFA

Mating Factor α TFA

α-Factor Mating Pheromone, yeast (TFA)为一来自S. cerevisiae的α细胞分泌的十三肽,通过Ste2p受体发挥作用。
T76027 β-Endorphin, equine TFA

β-Endorphin, equine TFA,是具备强效亲和力于μ和δ阿片受体(μ/δ opioid receptors)的内源性阿片类多肽,主要功能包括止痛。
T75967 Bactenecin TFA

Bactenecin TFA (Bactenecin, bovine TFA) 是一种从牛嗜中性粒细胞中分离出来的有效的含 12 个氨基酸的环状抗菌肽。Bactenecin TFA 抑制细菌和酵母菌 (bacteria 和 yeast) 的生长,并能杀死真菌红毛癣菌 (fungusTrichophyton rubrum)。Bactenecin TFA 增加了膜的通透性,抑制了假苹果芽孢杆菌 (B. pseudomallei) 的生长和生物膜的形成。
T75767 Parasin I TFA

Parasin I (TFA) 是一种含有19个氨基酸残基的多肽,源自鲶鱼皮肤中分离出的组蛋白H2A,具备抗菌功能。
T3809 Liriope muscari baily saponins C

Others Others
Liriope muscari baily saponins C 是一种L. muscari (Decne.) Baily 的主要活性成分。它已被作为肿瘤转移候选药物进行研究。它具有很强的抗炎、免疫药理和心脏保护作用。
T6S1256 Ruscogenin

NOS; NF-κB; NOD-like Receptor (NLR) Immunology/Inflammation; NF-κB
Ruscogenin 是一种重要甾体皂苷元,提取自麦冬。它能够抑制 TXNIP/NLRP3炎症体激活和 MAPK 途径,改善脑缺血诱导的血脑屏障功能障碍,具有显著抗血栓、抗炎作用。
T3229 Cytochalasin D

ATPase; p38 MAPK; Calcium Channel; Akt; PI3K Cytoskeletal Signaling; MAPK; Membrane transporter/Ion channel; Metabolism; PI3K/Akt/mTOR signaling
Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head decondensation. Cytochalasin D inhibit

天然产物

TF-DG-cThea
Cat.No: T81001
Synonym:
Target:
TF-3ʹ-G-cThea
Cat.No: T81002
Synonym:
Target:
TF-3-G-cThea
Cat.No: T81003
Synonym:
Target:
Theaflavin 3,3'-digallate
Cat.No: T5429
Synonym: 茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG
Target: Virus Protease, Antioxidant, HIV Protease, HSV
TFAP
Cat.No: T4643
Synonym: N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide
Target: COX, Endogenous Metabolite
Echistatin TFA
Cat.No: T36295
Synonym:
Target:
Magainin 1 TFA
Cat.No: T75753
Synonym:
Target:
Chlorotoxin TFA
Cat.No: T75722
Synonym:
Target:
Cecropin A TFA
Cat.No: T75974
Synonym:
Target:
Conantokin G TFA
Cat.No: T75890
Synonym:
Target:
Magainin 2 TFA
Cat.No: T83693
Synonym: MG2
Target:
L-Palmitoylcarnitine TFA
Cat.No: T73764
Synonym:
Target:
γ-Glu-Gly TFA
Cat.No: T35401
Synonym:
Target:
Cyclo(his-pro) TFA
Cat.No: T61171
Synonym:
Target:
HA Peptide TFA
Cat.No: T75743
Synonym:
Target:
α-Factor Mating Pheromone, yeast TFA
Cat.No: T78500
Synonym: Mating Factor α TFA
Target:
β-Endorphin, equine TFA
Cat.No: T76027
Synonym:
Target:
Bactenecin TFA
Cat.No: T75967
Synonym:
Target:
Parasin I TFA
Cat.No: T75767
Synonym:
Target:
Liriope muscari baily saponins C
Cat.No: T3809
Synonym:
Target: Others
Ruscogenin
Cat.No: T6S1256
Synonym:
Target: NOS, NF-κB, NOD-like Receptor (NLR)
Cytochalasin D
Cat.No: T3229
Synonym:
Target: ATPase, p38 MAPK, Calcium Channel, Akt, PI3K
Cat. No. Product Name Species Expression System
TMPY-02530 Tissue Factor Protein, Human, Recombinant (His)

CD142,coagulation factor III (thromboplastin, tissue factor)...

Human HEK293 Cells
Tissue Factor Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P13726.
TMPH-01514 IGIP Protein, Human, Recombinant (His & TF)

Human Baculovirus Insect Cells
Enhances IgA secretion from B-cells stimulated via CD40.
TMPK-00993 Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His)

Thromboplastin,CD142,TF,FLJ17960,TFA,F3,Co...

Canine HEK293 Cells
Tissue factor (also named Coagulation Factor III) is a cell surface glycoprotein responsible for initiating the extrinsic pathway of coagulation.Tissue factor is the primary cellular initiator of blood coagulation via interaction with coagulation factor VII. Aberrant expression of tissue factor is responsible for thrombosis during septic shock, atherosclerosis and cancer.
TMPY-01325 Tissue Factor Protein, Mouse, Recombinant (His)

Cf-3,AA409063,CD142,coagulation factor III (thromboplastin, ...

Mouse HEK293 Cells
Tissue Factor Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is A0A0R4J088.
TMPY-02537 Tissue Factor Protein, Human, Recombinant (hFc)

coagulation factor III,coagulation factor III (thromboplasti...

Human HEK293 Cells
Tissue Factor Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.8 kDa and the accession number is P13726.
TMPY-05083 Tissue Factor Protein, Human, Recombinant (aa 1-295, His)

coagulation factor 3,TF,TFA,coagulation fa...

Human Baculovirus Insect Cells
Tissue Factor Protein, Human, Recombinant (aa 1-295, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 31 kDa and the accession number is P13726-1.
TMPY-06957 Tissue Factor Protein, Human, Recombinant (hFc & Avi), Biotinylated

TFA,coagulation factor 3,coagulation factor III,CD1...

Human HEK293 Cells
Tissue Factor Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 53.34 kDa and the accession number is P13726.
TMPJ-00661 PDCD5 Protein, Human, Recombinant (His)

Programmed Cell Death Protein 5,Protein TFAR19,...

Human E. coli
Programmed Cell Death Protein 5 (PDCD5) is a member of the PDCD5 family. PDCD5 is expressed in tumor cells during apoptosis, independent of apoptosis-inducing stimuli. This protein may function in the process of apoptosis. PDCD5 is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. PDCD5 may play an important regulator of K (lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its pr...
TMPJ-01300 PDCD10 Protein, Human, Recombinant

TFAR15,Programmed Cell Death Protein 10,PDCD10,...

Human E. coli
Programmed Cell Death Protein 10 (PDCD10) belongs to the PDCD10 family. PDCD10 exists as a homodimer and is widely expressed. PDCD10 can increase mitogen-activated protein kinase activity and MST4 activity. PDCD10 is required for normal cardiovascular development and normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development. Defects in PDCD10 are the cause of cerebral cavernous malformations type 3.
TMPY-01873 Transferrin Receptor/TFRC Protein, Human, Recombinant (His)

TFR1,p90,CD71,TFR,transferrin receptor,T9,...

Human HEK293 Cells
Transferrin Receptor/TFRC Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 77.4 kDa and the accession number is AAA61153.1.
TMPY-05096 Transferrin Receptor/TFRC Protein, Human, Recombinant (hFc)

CD71,T9,transferrin receptor,TFR1,p90,TRFR,TF

Human HEK293 Cells
Transferrin Receptor/TFRC Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 103.6 kDa and the accession number is CAA25527.1.
TMPY-01864 CNTF Protein, Human, Recombinant (His)

ciliary neurotrophic factor,HCNTF

Human E. coli
CNTF Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.5 kDa and the accession number is P26441.
TMPY-01030 TFPI Protein, Human, Recombinant (His)

TFPI1,tissue factor pathway inhibitor (lipoprotein-...

Human HEK293 Cells
TFPI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.6 kDa and the accession number is P10646-1.
TMPY-03739 Transferrin Receptor/TFRC Protein, Cynomolgus, Rhesus, Recombinant (His)

transferrin receptor

Cynomolgus,Rhesus HEK293 Cells
Transferrin Receptor/TFRC Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 77.5 kDa and the accession number is XP_005545315.1&NP_001244232.1.
TMPY-02294 Transferrin Receptor/TFRC Protein, Mouse, Recombinant (His)

2610028K12Rik,p90,E430033M20Rik,AI426448,TFR,AU0157...

Mouse HEK293 Cells
Transferrin Receptor/TFRC Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.3 kDa and the accession number is Q62351.
TMPH-03211 TFPI Protein, Rabbit, Recombinant (His)

Rabbit HEK293 Cells
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. TFPI Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis tag. The predicted molecular weight is 35.4 kDa and the accession number is P19761.
TMPH-03210 TFPI Protein, Rabbit, Recombinant (E. coli, His)

Rabbit E. coli
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. TFPI Protein, Rabbit, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.8 kDa and the accession number is P19761.
TMPK-00194 TFPI Protein, Human, Recombinant (His & Avi)

LACI,EPI,TFPI,convertin,TFI,TFPI1

Human HEK293 Cells
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and has recently been associated with breast cancer cell development. TFPI Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 32.1 kDa and the accession number is P10646-1.
TMPK-00195 TFPI Protein, Human, Recombinant (His & Avi), Biotinylated

convertin,TFI,LACI,EPI,TFPI,TFPI1

Human HEK293 Cells
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and has recently been associated with breast cancer cell development. TFPI Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 32.1 kDa and the accession number is P10646-1.
TMPY-02444 ATF2 Protein, Human, Recombinant (His & GST)

CREB2,CRE-BP1,CREB-2,TREB7,activating transcription factor 2...

Human Baculovirus Insect Cells
Activating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP response element. Its activity is enhanced after phosphorylation by stress-activated protein kinases such as c-Jun N-terminal kinase and p38. ATF2 has been found to be a target of the JNK signal transduction pathway and mediate adenovirus E1A-inducible transcriptional activation. ATF2 is also been reported playing roles in TGF-β signaling pathway. It has ...
TMPK-00941 TFF1 Protein, Mouse, Recombinant (hFc)

HP1.A,D21S21,TFF1,Polypeptide P1.A,PS2,BCEI,pNR-2,H...

Mouse HEK293 Cells
Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in serum were associated with development of BC, TFF1 expression was upregulated in BC compared to the healthy breast tissue.That expression of TFF1 was related to ER status of BC and that expression of TFF1 was lower in TNBC than in non-TNBC. TFF1 Protein, Mouse, Recombinant (hFc) is e...
TMPH-00406 ctfB Protein, Clostridium acetobutylicum, Recombinant (His & Myc)

Butyrate--acetoacetate CoA-transferase subunit B,ctf

Clostridium acetobutylicum E. coli
Involved in solventogenic switch which allows C.acetobutylicum to uptake acid and produce solvents. Acts mainly to detoxify the medium by removing the acetate and butyrate excreted earlier in the fermentation. ctfB Protein, Clostridium acetobutylicum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.6 kDa and the accession number is P23673.
TMPH-00502 TFF3 Protein, Canine, Recombinant (His & Myc)

Canine E. coli
Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).
TMPY-05179 TFPI Protein, Human, Recombinant (His), Biotinylated

TFI,TFPI1,EPI,LACI,tissue factor pathway i...

Human HEK293 Cells
TFPI Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.6 kDa and the accession number is P10646-1.
TMPY-05617 Transferrin Receptor/TFRC Protein, Human, Recombinant (His), Biotinylated

TRFR,p90,TR,TFR,CD71,TFR1,T9,transferrin r...

Human HEK293 Cells
Transferrin Receptor/TFRC Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 77.4 kDa and the accession number is P02786.
TMPJ-01173 TFF3 Protein, Mouse, Recombinant (His)

Itf,Trefoil factor 3,Intestinal trefoil factor,mI

Mouse HEK293 Cells
Trefoil factors (TFF) are secretory products of mucin producing cells. They play a key role in the maintenance of the surface integrity of oral mucosa and enhance healing of the gastrointestinal mucosa by a process called restitution. TFF comprises the gastric peptides (TFF1), spasmolytic peptide (TFF2), and the intestinal trefoil factor (TFF3). They have an important and necessary role in epithelial restitution within the gastrointestinal tract. Members of the trefoil family are characterized b...
TMPY-05431 TFF1 Protein, Human, Recombinant (His)

trefoil factor 1,HP1.A,HPS2,pNR-2,D21S21,pS2,BCEI

Human HEK293 Cells
TFF1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 8.1 kDa and the accession number is P04155.
TMPK-00007 TFF1 Protein, Human, Recombinant (hFc)

Polypeptide P1.A,Trefoil factor 1,Bcei,HP1.A,pNR-2,PS2,HPS2,...

Human HEK293 Cells
Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in serum were associated with development of BC, TFF1 expression was upregulated in BC compared to the healthy breast tissue.That expression of TFF1 was related to ER status of BC and that expression of TFF1 was lower in TNBC than in non-TNBC. TFF1 Protein, Human, Recombinant (hFc) is e...
TMPH-00641 YTFE Protein, E. coli, Recombinant (GST)

E. coli E. coli
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions. YTFE Protein, E. coli, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 51.9 kDa and the accession number is P69506.
TMPJ-01079 TFF2 Protein, Mouse, Recombinant (His)

SP,Trefoil Factor 2,Spasmolytic polypeptide,Tff2,Sm...

Mouse HEK293 Cells
Recombinant Murine TFF-2 is an 11.9 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds. The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute a...
TMPY-02728 Lactoferrin/LTF Protein, Mouse, Recombinant (His)

MMS10R,Lf,Csp82,lactotransferrin,Ms10r

Mouse HEK293 Cells
Lactoferrin/LTF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 77.2 kDa and the accession number is AAH06904.1.
TMPY-02859 TFPI2 Protein, Mouse, Recombinant (hFc)

PP5/TFPI-2,AV000670,tissue factor pathway inhibitor...

Mouse HEK293 Cells
TFPI2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.4 kDa and the accession number is O35536.
TMPH-01164 ATF-3 Protein, Human, Recombinant (His)

ATF3,cAMP-dependent transcription factor ATF

Human E. coli
ATF3 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-02613 ATF-5 Protein, Mouse, Recombinant (His & Myc)

Transcription factor ATFx,Transcription factor-like...

Mouse E. coli
Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific response element (ARE) (consensus: 5'-C[CT]TCT[CT]CCTT[AT]-3') but also the amino acid response element (AARE), present in many viral and cellular promoters. Critically involved, often in a cell type-dependent manner, in cell survival, proliferation, and differentiation. Its transcrip...
TMPJ-00081 CNTF Protein, Human, Recombinant

CNTF,Ciliary Neurotrophic Factor

Human E. coli
Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83% homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor com...
TMPH-03388 Transferrin Receptor/TFRC Protein, Rat, Recombinant (His & SUMO)

Rat E. coli
Transferrin Receptor/TFRC Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.9 kDa and the accession number is Q99376.
TMPY-00928 TFPI Protein, Mouse, Recombinant (His)

AW552122,A630013F22Rik,tissue factor pathway inhibitor (lipo...

Mouse HEK293 Cells
TFPI Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is O54819-1.
TMPJ-00513 LTF Protein, Human, Recombinant (His)

Lactoferroxin-A,Talalactoferrin,LTF,Lactotransferri...

Human HEK293 Cells
Lactotransferrin is a member of the transferrin family that transfer iron to the cells and control the level of free iron in the blood and external secretions. Lactotransferrin is a secreted protein and contains two transferrin-like domains. Lactotransferrin can be cleaved into the following four chains: Kaliocin-1, Lactoferroxin-A, Lactoferroxin-B, and Lactoferroxin-C. Lactoferroxin A, Lactoferroxin B, and Lactoferroxin C have opioid antagonist activity. Lactoferroxin A shows preference for mu-...
TMPH-00886 ATF7IP2 Protein, Human, Recombinant (His)

MCAF2,ATF7-interacting protein 2,Activating transcr...

Human E. coli
Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (Probable). AT...
TMPH-03285 ETFDH Protein, Rat, Recombinant (His)

Rat E. coli
Accepts electrons from ETF and reduces ubiquinone. ETFDH Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 68.6 kDa and the accession number is Q6UPE1.
TMPH-01724 MRTFA Protein, Human, Recombinant (His & KSI)

Human E. coli
MRTFA Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 25.4 kDa and the accession number is Q969V6.
TMPY-01004 TFPI2 Protein, Human, Recombinant (His)

REF1,PP5,tissue factor pathway inhibitor 2,TFPI-2

Human HEK293 Cells
TFPI2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.2 kDa and the accession number is P48307-1.
TMPH-02243 TFF3 Protein, Human, Recombinant (GST)

Human E. coli
Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).
TMPY-04828 TFF3 Protein, Human, Recombinant (His)

trefoil factor 3 (intestinal),ITF,P1B,TFI

Human HEK293 Cells
Trefoil factor family (TFF) peptides are involved in the maintenance of epithelial integrity and epithelial restitution. Trefoil factor-3 (TFF3) is an estrogen-regulated gene associated with prognosis in different types of cancer. The presence and localization of TFF3 peptide was associated with the embryonic stage and tissue differentiation. TFF3 peptide distribution specific to the germ layers was not observed. The role of TFF3 peptide in cell migration and differentiation, immune response, an...
TMPJ-00886 ATF1 Protein, Human, Recombinant (His)

Cyclic AMP-dependent transcription factor ATF-1,Act...

Human E. coli
Cyclic AMP-dependent transcription factor ATF-1(ATF1) which contains 1 bZIP (basic-leucine zipper) domain and 1 KID (kinase-inducible) domain, belongs to the bZIP family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. It also binds to the ...
TMPY-02188 Lactoferrin/LTF Protein, Human, Recombinant (His)

HEL110,LF,HLF2,GIG12,lactotransferrin

Human HEK293 Cells
Lactoferrin/LTF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 77.5 kDa and the accession number is P02788.
TMPY-02008 CNTFR Protein, Rat, Recombinant (His)

ciliary neurotrophic factor receptor

Rat Baculovirus Insect Cells
CNTFR Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is Q08406-1.
TMPJ-00378 Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His)

p90,TfR,T9,Trfr,Transferrin receptor protein 1,TR

Human HEK293 Cells
Transferrin receptor protein 1 (TFRC) belongs to the peptidase M28 family that is synthesized as a 172 amino acid (aa). TFRC regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. It binds one transferrin or HFE molecule per subunit and binds the HLA class II histocompatibility antigen, DR1. It Interacts with SH3BP3 and STEAP3, facilitates TFRC endocytosis in erythroid precursor cells. Cellular uptake of iron o...
TMPH-03274 ATF-4 Protein, Rat, Recombinant (His & Myc)

cAMP-dependent transcription factor ATF-4,Activatin...

Rat E. coli
ATF-4 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 43.2 kDa and the accession number is Q9ES19.
TMPY-00523 CNTF Protein, Mouse, Recombinant (His)

AI429687,ciliary neurotrophic factor

Mouse E. coli
CNTF Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.7 kDa and the accession number is P51642.
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重组蛋白

Tissue Factor Protein, Human, Recombinant (His)
Cat.No: TMPY-02530
Species: Human
Expression System: HEK293 Cells
IGIP Protein, Human, Recombinant (His & TF)
Cat.No: TMPH-01514
Species: Human
Expression System: Baculovirus Insect Cells
Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His)
Cat.No: TMPK-00993
Species: Canine
Expression System: HEK293 Cells
Tissue Factor Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01325
Species: Mouse
Expression System: HEK293 Cells
Tissue Factor Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02537
Species: Human
Expression System: HEK293 Cells
Tissue Factor Protein, Human, Recombinant (aa 1-295, His)
Cat.No: TMPY-05083
Species: Human
Expression System: Baculovirus Insect Cells
Tissue Factor Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06957
Species: Human
Expression System: HEK293 Cells
PDCD5 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00661
Species: Human
Expression System: E. coli
PDCD10 Protein, Human, Recombinant
Cat.No: TMPJ-01300
Species: Human
Expression System: E. coli
Transferrin Receptor/TFRC Protein, Human, Recombinant (His)
Cat.No: TMPY-01873
Species: Human
Expression System: HEK293 Cells
Transferrin Receptor/TFRC Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05096
Species: Human
Expression System: HEK293 Cells
CNTF Protein, Human, Recombinant (His)
Cat.No: TMPY-01864
Species: Human
Expression System: E. coli
TFPI Protein, Human, Recombinant (His)
Cat.No: TMPY-01030
Species: Human
Expression System: HEK293 Cells
Transferrin Receptor/TFRC Protein, Cynomolgus, Rhesus, Recombinant (His)
Cat.No: TMPY-03739
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
Transferrin Receptor/TFRC Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02294
Species: Mouse
Expression System: HEK293 Cells
TFPI Protein, Rabbit, Recombinant (His)
Cat.No: TMPH-03211
Species: Rabbit
Expression System: HEK293 Cells
TFPI Protein, Rabbit, Recombinant (E. coli, His)
Cat.No: TMPH-03210
Species: Rabbit
Expression System: E. coli
TFPI Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00194
Species: Human
Expression System: HEK293 Cells
TFPI Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00195
Species: Human
Expression System: HEK293 Cells
ATF2 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-02444
Species: Human
Expression System: Baculovirus Insect Cells
TFF1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00941
Species: Mouse
Expression System: HEK293 Cells
ctfB Protein, Clostridium acetobutylicum, Recombinant (His & Myc)
Cat.No: TMPH-00406
Species: Clostridium acetobutylicum
Expression System: E. coli
TFF3 Protein, Canine, Recombinant (His & Myc)
Cat.No: TMPH-00502
Species: Canine
Expression System: E. coli
TFPI Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05179
Species: Human
Expression System: HEK293 Cells
Transferrin Receptor/TFRC Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05617
Species: Human
Expression System: HEK293 Cells
TFF3 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01173
Species: Mouse
Expression System: HEK293 Cells
TFF1 Protein, Human, Recombinant (His)
Cat.No: TMPY-05431
Species: Human
Expression System: HEK293 Cells
TFF1 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00007
Species: Human
Expression System: HEK293 Cells
YTFE Protein, E. coli, Recombinant (GST)
Cat.No: TMPH-00641
Species: E. coli
Expression System: E. coli
TFF2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01079
Species: Mouse
Expression System: HEK293 Cells
Lactoferrin/LTF Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02728
Species: Mouse
Expression System: HEK293 Cells
TFPI2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02859
Species: Mouse
Expression System: HEK293 Cells
ATF-3 Protein, Human, Recombinant (His)
Cat.No: TMPH-01164
Species: Human
Expression System: E. coli
ATF-5 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02613
Species: Mouse
Expression System: E. coli
CNTF Protein, Human, Recombinant
Cat.No: TMPJ-00081
Species: Human
Expression System: E. coli
Transferrin Receptor/TFRC Protein, Rat, Recombinant (His & SUMO)
Cat.No: TMPH-03388
Species: Rat
Expression System: E. coli
TFPI Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00928
Species: Mouse
Expression System: HEK293 Cells
LTF Protein, Human, Recombinant (His)
Cat.No: TMPJ-00513
Species: Human
Expression System: HEK293 Cells
ATF7IP2 Protein, Human, Recombinant (His)
Cat.No: TMPH-00886
Species: Human
Expression System: E. coli
ETFDH Protein, Rat, Recombinant (His)
Cat.No: TMPH-03285
Species: Rat
Expression System: E. coli
MRTFA Protein, Human, Recombinant (His & KSI)
Cat.No: TMPH-01724
Species: Human
Expression System: E. coli
TFPI2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01004
Species: Human
Expression System: HEK293 Cells
TFF3 Protein, Human, Recombinant (GST)
Cat.No: TMPH-02243
Species: Human
Expression System: E. coli
TFF3 Protein, Human, Recombinant (His)
Cat.No: TMPY-04828
Species: Human
Expression System: HEK293 Cells
ATF1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00886
Species: Human
Expression System: E. coli
Lactoferrin/LTF Protein, Human, Recombinant (His)
Cat.No: TMPY-02188
Species: Human
Expression System: HEK293 Cells
CNTFR Protein, Rat, Recombinant (His)
Cat.No: TMPY-02008
Species: Rat
Expression System: Baculovirus Insect Cells
Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His)
Cat.No: TMPJ-00378
Species: Human
Expression System: HEK293 Cells
ATF-4 Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03274
Species: Rat
Expression System: E. coli
CNTF Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00523
Species: Mouse
Expression System: E. coli
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