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Search Results for " sophora "

3

抑制剂 & 化合物

61

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T126196	Sophoraflavanone C
	Sophoraflavanone C 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126196。
T124490	Isosophoranone
	Isosophoranone 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124490，CAS号为 64280-18-8。
T32638	Leontalbinine N-oxide
	Leontalbinine N-oxide is a lupin alkaloid from Sophora flavescen seeds.

化合物

Sophoraflavanone C

Cat.No: T126196

Cat.No: T124490

Leontalbinine N-oxide

Cat.No: T32638

Cat. No.	Product Name	Target	Signaling Pathways
T3S0970	Thermopsine Thermospine,黄华碱	Antibacterial	Microbiology/Virology
	Thermopsine (Thermospine) 是从槐豆亚种的果实，豆荚和茎皮中分离出来的一种喹诺酮类生物碱，具有抗菌活性。
T5S1000	Sophoraflavanone G Kushenol F,槐黄烷酮 G,Vexibinol	Apoptosis	Apoptosis
	Sophoraflavanone G (Kushenol F) 是从苦参中提取到的一种天然产物，通过抑制 MAPK 相关通路诱导 MDA-MB-231 和 HL-60 细胞凋亡，具有抗肿瘤和抗炎特性。
TN2218	Sophorabioside	Others	Others
	Sophorabioside is a natural product from Sophora japonica.
TN2221	(-)-Sophoranone	Others	Others
	(-)-Sophoranone is a natural product from Sophora subprostrata.
TN5038	Sophoraflavanone I	Others	Others
	Sophoraflavanone I is a natural product from Sophora moorcroftiana.
TN5036	Sophoracarpan B	Others	Others
	Sophoracarpan B is a natural product from Sophora tomentosa L.
TN5037	Sophoraflavanone H	Others	Others
	Sophoraflavanone H is a natural product from Sophora moorcroftiana.
TN5035	Sophoracarpan A	Others	Others
	Sophoracarpan A is a natural product from Sophora tomentosa L.
TN4644	Neosophoramine	Others	Others
	Neosophoramine是一种天然产物，属于豆科苦参属，其产品编号为 TN4644，CAS号为 52932-74-8。Neosophoramine可用作对照参考。
TN2220	Sophoranol 槐醇,(+)-Sophoranol	HBV	Microbiology/Virology
	(+)-Sophoranol exhibits antiviral activity against the Coxsackie virus B3. It also shows potent anti-HBV activity with an inhibitory potency against HBsAg secretion and against HBeAg secretion.
TN2219	Sophoraisoflavone A 鲁冰花,砂生槐异黄酮 A	MRP; Antifection	Immunology/Inflammation; Microbiology/Virology
	Sophoraisoflavone A is a potential MRP inhibitor; it is also an inhibitor of germ tube growth in the AM fungus Gigaspora margarita, it strongly inhibited germ tube growth at 1.25 ug/disc. Sophoraisoflavone A shows inhibitory effects on copper-induced prot
TN3124	5-Hydroxysophoranone	Antibacterial; Parasite; Antifection	Microbiology/Virology
	5-Hydroxysophoranone 从 Erythrina subumbrans 茎中提取，对恶性疟原虫具有高抗疟原虫活性 (IC50 = 2.5 μg/mL)。
TN6855	Sophoramine
	Sophoramine is a natural product.
TN1781	Isokurarinone	Others	Others
	Isokurarinone 是一种来自苦参的天然产物。
T2870	Matrine Vegard,苦参碱,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine	Mitophagy; Ferroptosis; Opioid Receptor; Autophagy	Apoptosis; Autophagy; Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Matrine (Vegard) 是一种从槐属植物中分离出来的生物碱，可作为一种κ阿片受体激动剂，有抗肿瘤活性。
T2746	Sophocarpine monohydrate 槐果碱,Sophocarpine,槐果碱水合物	Apoptosis; Influenza Virus; Akt; PI3K; AMPK; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling
	Sophocarpine monohydrate 是从传统草药苦参中提取的一种重要生物碱，具有抗肿瘤活性，可用于肝细胞癌，前列腺癌和结肠直肠癌。苦参具有抗病毒，抗肿瘤和抗炎等多种药理作用。
T13768	(+)-Medicarpin	Estrogen/progestogen Receptor	Endocrinology/Hormones
	(+)-Medicarpin, a pterocarpan, is an isoflavonoid compound derived from multiple medicinal plant species such as Sophora japonica, Zollernia paraensis, Platymiscium yucatamun, Machaerium aristulatum, and Platymiscium floribundum. It exhibits potent inhibition of osteoclastogenesis and facilitates bone healing and increased bone mass through osteoblast differentiation, which is mediated by the estrogen receptor (ER) β.
T6S1010	Allomatrine 槐定碱,别苦参碱	Others	Others
	Allomatrine 是一种来源槐花树皮的生物碱。它能够激活 κ-阿片受体，进而产生缓解疼痛的作用。
TN1215	(2S)-2'-Methoxykurarinone 2'-甲氧基苦参黄素,2'-Methoxykurarinone,2'-O-Methylkurarinone	Akt; Antifection	Cytoskeletal Signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling
	(2S)-2'-Methoxykurarinone 是一种分离自苦参根中的化合物，具有抗炎、解热、抗糖尿病和抗肿瘤活性。它对人髓系白血病 HL-60 细胞具有细胞毒活性。它能够下调 RANKL 信号，抑制破骨细胞形成和骨吸收。
T2754	Oxymatrine Oxysophoridine,氧化苦参碱,Matrine N-oxide	Influenza Virus; Autophagy; TGF-beta/Smad	Autophagy; Microbiology/Virology; Stem Cells
	Oxymatrine (Oxysophoridine) 是来自槐属物种根部的一种生物碱，具有抗炎，抗纤维化和抗肿瘤的作用。它是一种用于治疗乙型肝炎病毒的中药。它可抑制博卡病毒 MVC 复制，降低病毒基因表达并减少病毒感染诱导的细胞凋亡。它还可以抑制 iNOS 的表达和 TGF-β/Smad 通路。
T5S0993	Kurarinone 苦参酮,苦参黄素	BCL; Others; IκB/IKK; TNF; NF-κB; JAK; STAT	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; NF-κB; Others; Stem Cells
	Kurarinone 是从灌木苦参中提取的黄酮类化合物，具有抗肿瘤、雌激素和抗炎活性，对免疫反应也有很强的抑制作用。
TN6967	(R)-Isomucronulatol (-)-Isomucronulatol,2H-1-Benzopyran-7-ol	Apoptosis	Apoptosis
	(R)-Isomucronulatol (2H-1-Benzopyran-7-ol) 是一种可从黄芪、刺槐、虎杖和甘草叶片中提取得到的类黄酮，抑制BMSCs 在TNF-α微环境中的增殖和凋亡。(R)-Isomucronulatol 具有潜在的抗炎活性。
T6677	Sophocarpine	ERK; p38 MAPK; NF-κB; TLR; COX; HER; JNK; STAT	Angiogenesis; Immunology/Inflammation; JAK/STAT signaling; MAPK; Neuroscience; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
	Sophocarpine 是一种从传统草药苦参中提取的重要生物碱。苦参具有抗病毒、抗肿瘤和抗炎等多种药理作用。它通过多种机制显著抑制癌细胞的生长，具有抗肿瘤活性。
TN7225	2'-Hydroxy-3,4-dimethoxychalcone	Antioxidant; Parasite	Microbiology/Virology; oxidation-reduction
	2'-Hydroxy-3,4-dimethoxychalcone 是从槐树根分离除的查耳酮化合物，具有抗氧化活性，抑制了多诺瓦尼乳杆菌寄生虫 EC 的细胞内存活50值介于 0.39 和 0.41 μg/mL 之间，可用于研究糖尿病，治疗血吸虫病、疟疾和其它感染。
TN3210	7,3'-Di-O-methylorobol	Others	Others
	7,3'-Di-O-methylorobol is a natural product from Sophora japonica L.
T8214	Kushenol E 苦参醇E,Flemiphilippinin D	IDO; Indoleamine 2,3-Dioxygenase (IDO)	Metabolism
	Kushenol E (Flemiphilippinin D) 是一种分离自Sophora flavescens 中的类黄酮，是一种IDO1的非竞争性抑制剂，其IC50=7.7 µM，Ki=为 9.5 µM，具有抗肿瘤特性。
T39394	(2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone
	(2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone is derived exclusively from the roots of Sophora flavescens.
T81809	Methylkushenol C
	甲基苦参新醇 C 是一种从苦参 (Sophora flavescens) 中分离得到的酚类化合物。
TN3179	6-Methylgenistein	Others	Others
	6-Methylgenistein is a natural product from Sophora dunnii.
TN1844	Kushenol L 苦参醇 L,苦参醇L	Others	Others
	Kushenol L是一种天然产物，属于豆科苦参属，其产品编号为 TN1844，CAS号为 101236-50-4。Kushenol L可用作对照参考。
T33170	Mamanine
	Mamanine is a metabolite of a lupine alkaloid isolated from leaves of Sophora glauca Lesch.
T80019	17-Hydroxyneomatrine
	17-Hydroxyneomatrine 是一种从苦参 (Sophora flavescens) 提取的化合物，有效抑制人宫颈癌Hela细胞生长，并展现抗菌、抗过敏、抗肿瘤、抗心律失常、消肿、利尿、免疫调节等多种生物活性。
T0772	Troxerutin 曲克芦丁,Trihydroxyethylrutin,维脑路通	NOD-like Receptor (NLR)	Immunology/Inflammation
	Troxerutin (Trihydroxyethylrutin) 是一种天然生物类黄酮芦丁的三羟乙基化衍生物，也被称为维生素 P4，可抑制活性氧的产生并抑制 ER 应激介导的NOD 活化。
TN4400	Kushenol M	Others	Others
	Kushenol M是一种天然产物，属于豆科苦参属，其产品编号为 TN4400，CAS号为 101236-51-5。Kushenol M可用作对照参考。
T4S0998	Trifolirhizin 红车轴草根甙/三叶豆紫檀苷,三叶豆紫檀苷	TNF; Tyrosinase	Apoptosis; Proteases/Proteasome
	Trifolirhizin 是一种从苦参根中分离出的 pterocarpan 黄酮类化合物。它具有酪氨酸酶高抑制活性，IC50=506 μM。它具有抗炎和抗癌的潜能。
T3339	Sophoridine 5-Epidihydrosophocarpine,槐定碱,Dihydro-5-episophocarpine	Apoptosis; Topoisomerase	Apoptosis; DNA Damage/DNA Repair
	Sophoridine (Dihydro-5-episophocarpine) 是一种从豆科植物槐豆斜生植物的叶子中分离出来的喹喔啉生物碱。它是胰腺癌的候选药物，诱导细胞凋亡。
T2S1008	Oxysophoridine Sophoridine N-oxide,氧化槐定碱	Apoptosis; Antioxidant	Apoptosis; oxidation-reduction
	Oxysophoridine (Sophoridine N-oxide) 是从苦豆子中提取的一种生物碱，具有抗发炎，抗氧化应激和抗凋亡的作用。
T5S0994	N-Methylcytisine N-甲基野靛碱,Caulophylline	Others; AChR	Neuroscience; Others
	N-Methylcytisine (Caulophylline) 是苦参中的一种三环喹啉类生物碱，具有降血糖、缓解疼痛和抗炎活性。它是中枢神经系统中乙酰胆碱烟碱受体的选择性配体，对鱿鱼视神经节中的烟碱乙酰胆碱受体具有很高的亲和力，Kd 为 50 nM。
T4S0999	(2S)-Isoxanthohumol Isoxanthohumol,(2S)-异黄腐酚,异黄腐醇	Virus Protease; HSV	Microbiology/Virology
	(2S)-Isoxanthohumol 是一种由啤酒花原异戊烯基二氢黄酮 Isoxanthohumol 的微生物转化代谢物。
T6377	Aloperine	Apoptosis; Virus Protease; HIV Protease; Antibiotic; Autophagy	Apoptosis; Autophagy; Microbiology/Virology; Proteases/Proteasome
	Aloperine 是一种在苦参类植物中的生物碱，其具有抗癌，抗炎、抗肿瘤和抗病毒特性，可用于研究过敏性接触性皮炎湿疹和其他皮肤炎症。
T2882	Genistin 染料木甙,Genistoside,Genistein glucoside,Genistein 7-glucoside,Genistine,Genistein 7-O-β-D-glucopyranoside,染料木苷	Apoptosis; Estrogen Receptor/ERR; Others	Apoptosis; Endocrinology/Hormones; Others
	Genistin (Genistoside) 是一种植物雌激素家族的异黄酮，是一种抗脂肪生成剂。它通过调节ERalpha 信号通路抑制乳腺癌细胞生长和促进凋亡细胞死亡。
TN1856	Leachianone A Isokurarinone,里查酮 A	SGLT	GPCR/G Protein
	Leachianone A (Isokurarinone) 是从槐花中分离的一种天然产物，可诱导细胞凋亡，具有抗疟疾、抗炎和细胞毒性作用。
T5901	3-Hydroxy-2-methylpyridine	Others	Others
	3-Hydroxy-2-methylpyridine 是分离自可可碱提取物，可用于合成嘧啶。
TN1840	Kurarinol	Tyrosinase; HBV; STAT	JAK/STAT signaling; Microbiology/Virology; Proteases/Proteasome; Stem Cells
	Kurarinol is a potent inhibitor of sortase A, with an IC50 value of 107.7 ± 6.6 μM. Kurarinol has extremely strong tyrosinase inhibitory activity, exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, is a candidate as skin-whitening agents.
TN2217	Sophoflavescenol 槐苦参醇,槐黄醇	Others; Beta-Secretase; BACE; PDE; AChR; AChE	Metabolism; Neuroscience; Others
	Sophoflavescenol 是异戊烯基黄酮类化合物，能够抑制PDE5的活性，IC50=0.013 μM。它也抑制 RLAR，HRAR，BACE1，AChE 和 BChE，IC50值分别为 0.30 µM，0.17 µM，10.98 µM，8.37 µM 和 8.21 µM。
TN3751	Daidzein-4'-glucoside	Others	Others
	Daidzein-4'-glucoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3751，CAS号为 58970-69-7。
TN5463	Leachianone G
	Leachianone G exhibits significant antioxidant potentials in the ABTS, ONOO(-), and total ROS assays, it also shows inhibitory activities against pancreatic lipase, it may be used as drug candidate to control obesity. Leachianone G shows potent antiviral
TN4993	Sepinol	Others	Others
	Sepinol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4993，CAS号为 72061-63-3。
TN3173	6-Hydroxywogonin	Others	Others
	6-Hydroxywogonin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3173，CAS号为 76844-70-7。
TN2709	2,4,6,6-Tetramethyl-3(6H)-pyridinone	Others	Others
	2,4,6,6-Tetramethyl-3(6H)-pyridinone 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2709，CAS号为 203524-64-5。
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天然产物

Cat.No: T3S0970

Synonym: Thermospine,黄华碱

Target: Antibacterial

Sophoraflavanone G

Cat.No: T5S1000

Synonym: Kushenol F,槐黄烷酮 G,Vexibinol

Target: Apoptosis

Sophorabioside

Cat.No: TN2218

Target: Others

(-)-Sophoranone

Cat.No: TN2221

Target: Others

Sophoraflavanone I

Cat.No: TN5038

Target: Others

Sophoracarpan B

Cat.No: TN5036

Target: Others

Sophoraflavanone H

Cat.No: TN5037

Target: Others

Sophoracarpan A

Cat.No: TN5035

Target: Others

Cat.No: TN4644

Target: Others

Cat.No: TN2220

Synonym: 槐醇,(+)-Sophoranol

Target: HBV

Sophoraisoflavone A

Cat.No: TN2219

Synonym: 鲁冰花,砂生槐异黄酮 A

Target: MRP, Antifection

5-Hydroxysophoranone

Cat.No: TN3124

Target: Antibacterial, Parasite, Antifection

Cat.No: TN6855

Cat.No: TN1781

Target: Others

Cat.No: T2870

Synonym: Vegard,苦参碱,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine

Target: Mitophagy, Ferroptosis, Opioid Receptor, Autophagy

Sophocarpine monohydrate

Cat.No: T2746

Synonym: 槐果碱,Sophocarpine,槐果碱水合物

Target: Apoptosis, Influenza Virus, Akt, PI3K, AMPK, Autophagy

Cat.No: T13768

Target: Estrogen/progestogen Receptor

Cat.No: T6S1010

Synonym: 槐定碱,别苦参碱

Target: Others

(2S)-2'-Methoxykurarinone

Cat.No: TN1215

Synonym: 2'-甲氧基苦参黄素,2'-Methoxykurarinone,2'-O-Methylkurarinone

Target: Akt, Antifection

Cat.No: T2754

Synonym: Oxysophoridine,氧化苦参碱,Matrine N-oxide

Target: Influenza Virus, Autophagy, TGF-beta/Smad

Cat.No: T5S0993

Synonym: 苦参酮,苦参黄素

Target: BCL, Others, IκB/IKK, TNF, NF-κB, JAK, STAT

(R)-Isomucronulatol

Cat.No: TN6967

Synonym: (-)-Isomucronulatol,2H-1-Benzopyran-7-ol

Target: Apoptosis

Cat.No: T6677

Target: ERK, p38 MAPK, NF-κB, TLR, COX, HER, JNK, STAT

2'-Hydroxy-3,4-dimethoxychalcone

Cat.No: TN7225

Target: Antioxidant, Parasite

7,3'-Di-O-methylorobol

Cat.No: TN3210

Target: Others

Cat.No: T8214

Synonym: 苦参醇E,Flemiphilippinin D

Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)

(2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone

Cat.No: T39394

Methylkushenol C

Cat.No: T81809

6-Methylgenistein

Cat.No: TN3179

Target: Others

Cat.No: TN1844

Synonym: 苦参醇 L,苦参醇L

Target: Others

Cat.No: T33170

17-Hydroxyneomatrine

Cat.No: T80019

Cat.No: T0772

Synonym: 曲克芦丁,Trihydroxyethylrutin,维脑路通

Target: NOD-like Receptor (NLR)

Cat.No: TN4400

Target: Others

Cat.No: T4S0998

Synonym: 红车轴草根甙/三叶豆紫檀苷,三叶豆紫檀苷

Target: TNF, Tyrosinase

Cat.No: T3339

Synonym: 5-Epidihydrosophocarpine,槐定碱,Dihydro-5-episophocarpine

Target: Apoptosis, Topoisomerase

Cat.No: T2S1008

Synonym: Sophoridine N-oxide,氧化槐定碱

Target: Apoptosis, Antioxidant

N-Methylcytisine

Cat.No: T5S0994

Synonym: N-甲基野靛碱,Caulophylline

Target: Others, AChR

(2S)-Isoxanthohumol

Cat.No: T4S0999

Synonym: Isoxanthohumol,(2S)-异黄腐酚,异黄腐醇

Target: Virus Protease, HSV

Cat.No: T6377

Target: Apoptosis, Virus Protease, HIV Protease, Antibiotic, Autophagy

Cat.No: T2882

Synonym: 染料木甙,Genistoside,Genistein glucoside,Genistein 7-glucoside,Genistine,Genistein 7-O-β-D-glucopyranoside,染料木苷

Target: Apoptosis, Estrogen Receptor/ERR, Others

Cat.No: TN1856

Synonym: Isokurarinone,里查酮 A

Target: SGLT

3-Hydroxy-2-methylpyridine

Cat.No: T5901

Target: Others

Cat.No: TN1840

Target: Tyrosinase, HBV, STAT

Sophoflavescenol

Cat.No: TN2217

Synonym: 槐苦参醇,槐黄醇

Target: Others, Beta-Secretase, BACE, PDE, AChR, AChE

Daidzein-4'-glucoside

Cat.No: TN3751

Target: Others

Cat.No: TN5463

Cat.No: TN4993

Target: Others

6-Hydroxywogonin

Cat.No: TN3173

Target: Others

2,4,6,6-Tetramethyl-3(6H)-pyridinone

Cat.No: TN2709

Target: Others

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