173
3
172
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T15597L |
ISA-2011B-P2
|
||
ISA-2011B-P2 是 ISA-2011B 的立体异构体。ISA-2011B 是有效的 PIP5K1α 抑制剂, 具有抗肿瘤活性。 | |||
T40925 |
Peripheral Myelin Protein P2 (53-78), bovine
Peripheral Myelin Protein P2 (53-78), bovine |
||
Bovine Peripheral Myelin Protein P2 (53-78) is a derivative composed of amino acid residues 53 to 78 from the peripheral myelin P2 protein of bovine origin. It acts as a T cell epitope and is used to induce experimental autoimmune neuritis (EAN) in Lewis rats. | |||
T25098 |
Antiflammin P2
Hdmnkvldl,Antiflamin 2,His-asp-met-asn-lys-val-leu-asp-leu |
||
Antiflammin P2 is a nonapeptide fragment of lipocortin I which has no phospholipase A2 inhibitory and anti-inflammatory activity. | |||
T62402 |
TTA-P2
|
||
TTA-P2 (T-Type calcium channel inhibitor) 是一种 T 型钙通道的有效抑制剂。TTA-P2 能够有效的穿透 CNS 并阻断小脑深部核神经元中的天然 T 型电流,完全消除野生型和突变型 Cav3.1 通道的窗口电流。TTA-P2 具有潜力进行神经疾病的研究。 | |||
TMIH-0573 |
Thiothixene-d8 P2
|
||
Thiothixene-d8 P2 是 Thiothixene 的氘代化合物。Thiothixene 的 CAS 号为 3313-26-6。(Z)-Thiothixene 是一种血清素受体拮抗剂。 | |||
TMIH-0291 |
Ketorolac-d5-P2
|
||
Ketorolac-d5-P2 是 Ketorolac 的氘代化合物。Ketorolac 的 CAS 号为 74103-06-3。Ketorolac 是非甾体抗炎剂,是非选择性的COX抑制剂,对 COX-1 和 COX-2 的IC50值分别为 20 和 120 nM。 | |||
T27499 |
GSK-A1
|
HCV Protease; PI4K | Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome |
GSK-A1 是 III 型磷脂酰肌醇 4-激酶 PI4KA 选择性抑制剂,pIC50为 8.5-9.8,抑制 PtdIns(4,5)P2 再合成,IC50约为 3 nM。GSK-A1有效降低 PtdIns(4)P 的水平,而对 PtdIns(4,5)P2 没影响。GSK-A1在抗丙型肝炎病毒方面有研究的潜力。 | |||
T20731 |
Brilliant blue G-250
酸性蓝 90,BBG,Acid blue 90, Coomassie Brilliant Blue G,Brilliant Blue G |
P2X Receptor | Membrane transporter/Ion channel; Neuroscience |
Brilliant blue G-250 (Acid blue 90, Coomassie Brilliant Blue G) 是一种可视化的染料,常用于 SDS-PAGE 分离蛋白质,染色过程简单,定量高。在 Bradford 蛋白质分析中,它能够与蛋白质结合,通过595 nm 处的吸光度确定蛋白质浓度。它也是一种安全的 P2×7R 选择性拮抗剂,有望使 NLRP3炎症体失活。 | |||
T67946 |
EP2 receptor antagonist-2
|
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
EP2 receptor antagonist-2 (CID891729)为EP2受体拮抗剂,能够抑制PGE2诱导的EP2受体激活,并阻断由N-甲基-D-天冬氨酸(NMDA)引起的乳酸脱氢酶(LDH)释放。 | |||
T19345 |
GP2-114
|
Others | Others |
GP2-114 是一种儿茶酚胺运动模拟剂 ,可用于研究冠状动脉疾病 (CAD)。 | |||
T37088L |
pep2m aceate
|
Others | Others |
pep2m aceate 是 GluR2 亚基 C 端与 N-乙基马来酰亚胺敏感融合蛋白相互作用的肽抑制剂。 | |||
TP1943L1 |
pep2-EVKI acetate(1315378-67-6 free base)
|
GluR | Neuroscience |
pep2-EVKI acetate(1315378-67-6 free base) 是一种细胞渗透性肽。 它干扰与 C 激酶 (PICK1) 相互作用的蛋白质和 GluR2 AMPA 受体亚基之间的相互作用。 | |||
T2035 |
WHI-P258
|
EGFR; JAK; JNK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; MAPK; Stem Cells; Tyrosine Kinase/Adaptors |
WHI-P258 是喹唑啉化合物,结合到JAK3的活性位点(Ki:72 µM)。甚至当WHI-P258到达 100 μM 时也不会抑制 JAK3 ,且对凝血酶诱导的血小板聚集无影响。 | |||
T9070 |
ASP2905
ASP-2905 |
Potassium Channel | Membrane transporter/Ion channel |
ASP-2905 是一种有效且选择性的钾通道 Kv12.2抑制剂。ASP2905 (ASP-2905) 可以穿越血脑屏障并具有抗精神病活性。 | |||
T4253 |
Skp2 Inhibitor C1
SKPin C1 |
Others; E1/E2/E3 Enzyme | Others; Ubiquitination |
Skp2 Inhibitor C1 (SKPin C1)(SKPin C1)是Skp2介导p27降解的特异性抑制剂。 | |||
T28284 |
P22074
P-22074 |
DUB | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination |
P22074是一种USP7抑制剂。它不像其卤代相关化合物那样是一种活跃的拮抗剂。P22074 具有抗肿瘤活性。 | |||
TP1777L |
p2Ca acetate(142606-55-1 free base)
|
Others | Others |
p2Ca acetate(142606-55-1 free base) 是一种天然加工的肽,来源于普遍存在的酶 α-酮戊二酸脱氢酶,并被 CTL 克隆 (2C) 识别为与 I 类 MHC 蛋白 Ld 结合。 | |||
T24494 |
MP265
S-(4-氯苄基)氯化异硫脲,MP-265,MP 265 |
Others | Others |
MP265 破坏 MreB 细胞骨架并具有抗增殖作用。 | |||
T7685 |
USP25/28 inhibitor AZ1
AZ1 |
DUB | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination |
USP25/28 inhibitor AZ1 (AZ1) 是一种口服有效,选择性,非竞争性的双重泛素特异性蛋白酶 USP25/28抑制,IC50分别为 0.7 μM 和0.6 μM。它有抗炎和抗肿瘤作用。 | |||
T61326 |
AIMP2-DX2-IN-1
|
Others | Others |
AIMP2-DX2-IN-1 是一种有效的 AIMP2-DX2 抑制剂,具有潜在的抗肿瘤活性,可用于研究淋巴癌。 | |||
T6266 |
PP2
AGL 1879,AG 1879,AGL 1879 |
EGFR; Tyrosine Kinases; JAK; Src | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors |
PP2 (AG 1879,AGL 1879) 是 Lck/Fyn 抑制剂 (IC50:4/5 nM),对 EGFR 的效力降低约 100 倍,对 ZAP-70、PKA 和 JAK2 无活性。 | |||
T1857 |
TMP269
|
HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair |
TMP269 是一种有效的特异性 IIa 类 HDAC 抑制剂,分别抑制 HDAC 4/HDAC 5/HDAC 7/HDAC 9,IC50值分别为 157 nM,97 nM,43 nM 和 23 nM。 | |||
T68455 |
AP23846
AP-23846 |
Src | Angiogenesis; Tyrosine Kinase/Adaptors |
AP23846 是一种新型高效的 Src 家族激酶抑制剂,可降低人实体瘤细胞系中血管内皮生长因子和白细胞介素-8 的表达,并消除下游血管生成过程。 | |||
TP1945L1 |
Pep2m, myristoylated acetate
Pep2m, myristoylated acetate(1423381-07-0 free base) |
PKC | Chromatin/Epigenetic; Cytoskeletal Signaling |
Pep2m, myristoylated acetate(1423381-07-0 free base) 是一种细胞可渗透的肉豆蔻酰化形式的 pep2m。 GluA2(AMPA 受体)亚基的 C 末端与 N-乙基马来酰亚胺敏感融合蛋白 (NSF)(一种调节 AMPA 受体功能的蛋白质)之间相互作用的肽抑制剂。降低 CA1 神经元中的突触后电流、培养的海马神经元中 AMPA 介导的电流和 AMPA 受体表面表达。 | |||
TP1909L1 |
CALP2 acetate(261969-04-4 free base)
|
CaMK; PDE | Metabolism; Neuroscience |
CALP2 acetate 是一种钙调蛋白拮抗剂,对与 CaM EF-hand/Ca2+-结合位点具有高亲和力,Kd 为 7.9 µM。它有效抑制粘附和脱粒。它也是肺泡巨噬细胞的强激活剂。它抑制 CaM 依赖性磷酸二酯酶活性并增加细胞内 Ca2+ 浓度。 | |||
T7265 |
HSP27 inhibitor J2
J2 |
HSP | Cytoskeletal Signaling; Metabolism |
HSP27 inhibitor J2 (J2) 是一种HSP27抑制剂,可显著增强 17-AAG 的抗增殖活性,并对顺铂诱导的肺癌细胞生长抑制具有敏感性。它显著诱导异常 HSP27 二聚体形成并抑制HSP27巨聚合物的产生,从而具有抑制HSP27的伴侣功能和降低细胞保护功能的作用。 | |||
T12728 |
RIP2 Kinase Inhibitor 3
|
Others; RIP kinase | Apoptosis; NF-κB; Others |
RIP2 Kinase Inhibitor 3 是一种有效的选择性 受体相互作用蛋白2 激酶抑制剂,IC50 为 1 nM。 | |||
TP1942L1 |
pep2-AVKI acetate(1315378-69-8 free base)
|
Others | Others |
pep2-AVKI acetate(1315378-69-8 free base) 选择性破坏 AMPA 受体亚基 GluA2(在 C 末端 PDZ 位点)与与 C 激酶 (PICK1) 相互作用的蛋白质结合的抑制剂肽。不影响 GluA2 与 GRIP 或 ABP 的结合,也不增加 AMPA 电流幅度或影响长期抑制 (LTD)。 | |||
T79600 |
Zharp2-1
|
RIP kinase | Apoptosis; NF-κB |
Zharp2-1是一种 RIPK2 抑制剂,抑制了 MDP 诱导或单核细胞增生李斯特菌感染诱导的炎症细胞因子的转录,缓解MDP诱导的小鼠腹膜炎症状,可用于研究炎症性肠病 (IBD)。 | |||
T10904 |
CWP232228
|
Wnt/beta-catenin | Cytoskeletal Signaling; Stem Cells |
CWP232228 是一种高效的、选择性的Wnt/β-catenin 信号通路抑制剂,在细胞核中,拮抗 β-catenin 与 T 细胞因子结合。它能够抑制乳腺癌和肝癌干细胞的生长,抑制肿瘤的形成和转移,且没有毒性。 | |||
T73151 |
USP22-IN-1
|
DUB | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination |
USP22-IN-1是一种泛素特异性肽酶22(USP22)抑制剂,可用于治疗增殖性疾病或癌症。 | |||
T72043 |
SCFSkp2-IN-2
|
Apoptosis; E1/E2/E3 Enzyme | Apoptosis; Ubiquitination |
SCFSkp2-IN-2 是一种 Skp2抑制剂,其 KD 为 28.77 μM。AAA-237 诱导 NSCLC 细胞凋亡 (apoptosis),显示出抗肿瘤活性。 | |||
T61271 |
MMP2-IN-3
|
MMP | Proteases/Proteasome |
MMP2-IN-3是一种有效的基质金属蛋白酶(MMP-2)抑制剂( IC50 值:31 μM)。MMP2-IN-3 抑制 MMP-9 和 MMP-8 ,其 IC50 分别为 26.6 和 32 μM。 | |||
T14299 |
AP20187
B/B Homodimerizer |
Others | Others |
AP20187 (B/B Homodimerizer) 是一种细胞渗透性配体,用于二聚化 FK506 结合蛋白 (FKBP) 融合蛋白。它启动生物信号级联和基因表达或破坏蛋白质-蛋白质相互作用。 | |||
T39738 |
ASP2453
|
Ras | GPCR/G Protein; MAPK |
ASP2453是选择性的KRAS G12C 共价抑制剂,抑制Son of Sevenless 介导的KRAS G12C 和Raf 之间的相互作用,IC50为40 nM。 | |||
T62420 |
P2Y2R/GPR17 antagonist 1
|
GPR | Endocrinology/Hormones; GPCR/G Protein |
P2Y2R/GPR17 antagonist 1 (Compound 14m) 是一种双重的 P2Y2R (IC50: 3.17 μM) 和 GPR17 (IC50: 1.67 μM) 拮抗剂。P2Y2R/GPR17 antagonist 1 在人肝微粒体中表现出极好的代谢稳定性。 | |||
T3684 |
CP21R7
CP21 |
GSK-3; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Stem Cells |
CP21R7 (CP21) 是一种 GSK-3β抑制剂,其 IC50=1.8 nM。它也是一种 PKCα抑制剂,其 IC50=1900 nM。 | |||
TP1944L1 |
pep2-SVKI acetate
pep2-SVKI acetate(328944-75-8 free base) |
GluR | Neuroscience |
Pep2-SVKI acetate(pep2-SVKI acetate (328944-75-8 free base)) 是一种合成肽盐,可防止 AMPA 型谷氨酸受体的内化。 | |||
T74794 |
USP28-IN-4
|
DUB | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination |
USP28-IN-4 是一种高效的 USP28 抑制剂,对 USP28 的 IC50 值为 0.04 μM。USP28-IN-4 具有抗癌活性,抑制 USP2、USP7、USP8、USP9x、UCHL3和UCHL5。USP28-IN-4 对人结直肠癌和肺鳞癌细胞具有细胞毒性,通过泛素-蛋白酶体系统对c-Myc的细胞水平进行剂量依赖性下调。 | |||
T14984 |
CLP257
|
Potassium Channel | Membrane transporter/Ion channel |
CLP257 是有效的 K+-Cl- 协同转运蛋白 KCC2 选择性激活剂 (EC50: 616 nM)。它可减轻神经性疼痛大鼠的超敏反应,并在翻译后调节质膜 KCC2 蛋白周转。它在 KCC2 活性降低的神经元中恢复受损的 Cl- 转运。 | |||
T12901 |
SHIP2-IN-1
|
Phosphatase | Metabolism |
SHIP2-IN-1 是一种 SHIP2 抑制剂,IC50=2 µM。它能够使 GSK3β 的 Ser9 位点磷酸化,抑制 GSK3β 的活化。它可用于研究阿尔滋海默症。 | |||
T5444 |
CLP290
CLP-290 |
Potassium Channel | Membrane transporter/Ion channel |
CLP-290 是一种神经特异性 K+-Cl−共转运体 KCC2的口服激活剂,在多种神经和精神疾病方面具有研究潜力。CLP290 能显著降低 STZ 大鼠的血液中 AVP 和血糖水平。 | |||
T2304 |
SP2509
HCI-2509 |
Apoptosis; Histone Demethylase | Apoptosis; Chromatin/Epigenetic |
SP2509 是一种选择性 LSD1拮抗剂,IC50值为 13 nM。 | |||
T74793 |
USP28-IN-3
|
DUB | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination |
USP28-IN-3是一种高选择性 USP28 抑制剂,对USP28的IC50 值为 0.1 μM。USP28-IN-3 具有抗癌活性,抑制 USP2、USP7、USP8、USP9x、UCHL3和UCHL5。USP28-IN-3 对人结直肠癌和肺鳞癌细胞具有细胞毒性,通过泛素-蛋白酶体系统对c-Myc的细胞水平进行剂量依赖性下调。 | |||
T63496 | CYP2C9/CYP2C19-IN-1 | ||
CYP2C9/CYP2C19-IN-1 是无肝脏毒性和遗传毒性的CYP2C9/CYP2C19强效抑制剂,能够用于研究寨卡病毒 (ZIKV) 感染。 | |||
T68766 | Dp2mT | ||
Dp2mT is an iron chelator which inhibits HIV-1 transcription. | |||
T63337 | CYP2C19-IN-1 | ||
CYP2C19-IN-1 是强效的,无遗传毒性的、无肝脏毒性的 CYP2C19 抑制剂。 CYP2C19-IN-1 能够抑制 RNA 依赖的 RNA 聚合酶 (RdRP) (Ki: 6.16 μM),能够用于研究寨卡病毒 (ZIKV) 感染。 | |||
T62685 | IMP2-IN-2 | ||
IMP2-IN-2 是一种有效的、选择性的 IMP2 抑制剂,抑制 IMP2 与 RNA_A 和 RNA_B 相互作用的 IC50 值分别为 120.9 μM 和 236.7 μM。IMP2-IN-2 能够用于研究癌症。 | |||
TP2149 |
NP213 TFA (942577-31-3 free base)
NP213 TFA |
Others | Others |
NP213 TFA is a rapidly acting and first-in-class synthetic antimicrobial peptide (AMP) with anti-fungal activity. It targets the fungal cytoplasmic membrane via membrane perturbation and disruption. | |||
T61891 | SHP2-IN-8 | ||
SHP2-IN-8 是一种可逆、非竞争性、选择性、高效性的变构SHP2抑制剂(IC50= 23 nM,Ki= 22 nM),在细胞中也有效果。SHP2-IN-8 能引起显著的热位移(ΔTm = 7.01 ℃)。SHP2-IN-8 可抑制AKT 的磷酸化,诱导 Hela 细胞凋亡 (apoptosis)。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1997 |
Notoginsenoside FP2
三七皂苷FP2 |
Others | Others |
Notoginsenoside FP2 是从三七 Panax notoginseng 果实花梗中分离得到的天然产物,可用于治疗心血管疾病的研究。 | |||
T1352 |
ATP disodium salt
Adenosine 5'-triphosphate disodium salt,三磷酸腺苷二钠,ATP,ATP disodium,腺苷-5'-三磷酸二钠盐,Adetide,Adenosine-Triphosphate,Disodium adenosine triphosphate |
P2X Receptor; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism; Neuroscience |
ATP disodium salt (Adenosine-Triphosphate) 是体内能量储存的重要物质,为代谢提供能量,同时在细胞中作为辅酶发挥作用。Adenosine 5'-triphosphate disodium salt 也是免疫和炎症中重要的内源性信号分子。 | |||
TN4088 |
Futoenone
|
PAFR | GPCR/G Protein |
Futoenone and a series of its derivatives have shown inhibitory activities against matrix metalloproteinases, the molecular modelings of these compounds indicate the preferred binding of the P2' site of the enzymes. Neolignan derivative compounds of the 2,4-diaryl-1,3-dithiolane and futoenone variety exhibit both platelet activating factor receptor(PAF)and 5-lipoxygenase antagonist activity. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01563 |
PMP2 Protein, Human, Recombinant (His)
MP2,FABP8,peripheral myelin protein 2,P2,M... |
Human | E. coli |
Myelin P2 protein, also known as PMP2, is a cytosolic protein found primarily in peripheral nerves. It Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. PMP2 is a small, basic, and cytoplasmic lipid binding protein of peripheral myelin. It is similar in amino acid sequence and tertiary structure to fatty acid binding proteins found in the liver, adipocytes, and intestine, its expression is limited to the nervous system. PMP2 is detected only in myelin-producing cells ... | |||
TMPH-03184 |
P2 Protein, Pseudomonas phage phi6, Recombinant (His & Myc)
|
Pseudomonas phage phi6 | E. coli |
Rna-dependent RNA polymerase part of the packaging complex that packages the viral RNA segments, replicate them into a double-stranded form and transcribe them. P2 Protein, Pseudomonas phage phi6, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.2 kDa and the accession number is P11124. | |||
TMPH-00182 |
Cry2Aa Protein, Bacillus thuringiensis subsp., Recombinant (His & Myc)
cryB1,P2 crystal protein,Crystaline entomocidal pro... |
Bacillus thuringiensis subsp. kurstaki | E. coli |
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of both dipteran (Aedes aegypti) and lepidopteran (Manduca sexta) larvae. Cry2Aa Protein, Bacillus thuringiensis subsp., Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.7 kDa and the accession number is P0A377. | |||
TMPH-02569 |
WISP2/CCN5 Protein, Mouse, Recombinant (His)
|
Mouse | P. pastoris (Yeast) |
May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production. | |||
TMPY-00463 |
ENPP2 Protein, Cynomolgus, Recombinant (His)
ENPP2,ectonucleotide pyrophosphatase/phosphodiester... |
Cynomolgus | HEK293 Cells |
ENPP2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 96 kDa and the accession number is XP_005564040.1. | |||
TMPY-04192 |
HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His)
Gag-p24 |
HIV | E. coli |
HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P04591. | |||
TMPY-01552 |
HIV-1 (group M, subtype B, strain 92418) p24 Protein (His)
Gag-p24 |
HIV | E. coli |
HIV-1 (group M, subtype B, strain 92418) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is B6DRA0. | |||
TMPY-02778 |
ENPP2 Protein, Human, Recombinant (His)
ATX,ectonucleotide pyrophosphatase/phosphodiesterase 2,AUTOT... |
Human | HEK293 Cells |
ENPP2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 96 kDa and the accession number is AAH34961.1. | |||
TMPK-01149 |
XPNPEP2 Protein, Rat, Recombinant (His)
Xaa-Pro aminopeptidase 2,Xpnpep2,Aminoacylproline a... |
Rat | HEK293 Cells |
Aminopeptidase P2 (XPNPEP2) is a receptor for TMTP1 tumor-homing peptide. However, the biological and clinical significance of Aminopeptidase P2 in human cancers remains unknown. XPNPEP2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 72.05 kDa and the accession number is Q99MA2. | |||
TMPK-00629 |
XPNPEP2 Protein, Mouse, Recombinant (His)
Xpnpep2,Aminoacylproline aminopeptidase,Xaa-Pro ami... |
Mouse | HEK293 Cells |
Aminopeptidase P2 (XPNPEP2) is a receptor for TMTP1 tumor-homing peptide. However, the biological and clinical significance of Aminopeptidase P2 in human cancers remains unknown. XPNPEP2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 72.24 kDa and the accession number is B1AVD1. | |||
TMPK-00333 |
IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-1 Rrp2,IL-1 R6,IL1RL2,IL1RRP2,IL-36R |
Human | HEK293 Cells |
IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 39.1 kDa and the accession number is Q9HB29-1. | |||
TMPH-00455 |
OBP28 Protein, Culex quinquefasciatus, Recombinant (His)
|
Culex quinquefasciatus | P. pastoris (Yeast) |
N/A. OBP28 Protein, Culex quinquefasciatus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 16.1 kDa and the accession number is B0XC79. | |||
TMPH-01736 |
PGLYRP2 Protein, Human, Recombinant (His)
|
Human | P. pastoris (Yeast) |
May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. PGLYRP2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 62.0 kDa and the accession number is Q96PD5. | |||
TMPH-02570 |
WISP2/CCN5 Protein, Mouse, Recombinant (His & SUMO)
|
Mouse | E. coli |
May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production. | |||
TMPY-06420 |
SARS-CoV-2 Spike S1 Protein (P26S & 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H, His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (P26S & 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 75.77 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-06682 |
PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His)
hPD-1,hSLE1,hPD-l,CD279,PD1,PD-1,programmed cell death 1,SLE... |
Human | HEK293 Cells |
PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.65 kDa and the accession number is NP_005009.2. | |||
TMPH-02131 |
SKP2 Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1, CDT1, RBL2, KMT2A/MLL1, CDK9, RAG2, FOXO1, UB... | |||
TMPH-02523 |
AQP2 Protein, Mouse, Recombinant (His)
ADH water channel,cph,Water channel protein for renal collec... |
Mouse | E. coli |
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential role in renal water homeostasis. AQP2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 30.5 kDa and the accession number is P56402. | |||
TMPH-01737 |
PGLYRP2 Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. PGLYRP2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 76.0 kDa and the accession number is Q96PD5. | |||
TMPK-00496 |
MASP2 Protein, Cynomolgus, Recombinant (His)
MAP19,MASP1P1,MASP-2,sMap |
Cynomolgus | E. coli |
MASP2 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.8 kDa and the accession number is A0A2K5UJY0. | |||
TMPK-01533 |
HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi)
MHC,LMP2,RING12,PSMB9,Macropain chain 7,Proteasome ... |
Human | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma... | |||
TMPH-03231 |
AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO)
Cysteine-rich antifungal protein 2,Defensin-like protein 2,R... |
Raphanus sativus | E. coli |
Possesses antifungal activity sensitive to inorganic cations. Induces potential changes in fungal membranes and increased K(+) efflux and Ca(2+) uptake. AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 21.7 kDa and the accession number is P30230. | |||
TMPY-04196 |
HIV-1 (group M, subtype D, strain NDK) p24 Protein (His)
Gag-p24 |
HIV | E. coli |
HIV-1 (group M, subtype D, strain NDK) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P18800. | |||
TMPH-01233 |
DIP2C Protein, Human, Recombinant (His)
DIP2 homolog C,DIP2C,KIAA0934,Disco-intera... |
Human | Baculovirus Insect Cells |
DIP2C Protein, Human, Recombinant (His) is expressed in Baculovirus. | |||
TMPH-01185 |
CYP2C19 Protein, Human, Recombinant (His & Myc)
Cytochrome P450 2C19,(R)-limonene 6-monooxygenase,(S)-limone... |
Human | E. coli |
CYP2C19 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-03757 |
TPP2 Protein, Human, Recombinant (E. coli, His & Myc)
|
Human | E. coli |
Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to some extent under conditions in which the latter is inhibited. Stimulates adipogenesis. TPP2 Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.8 kDa and the accession number is P29144. | |||
TMPJ-01336 |
SENP2 Protein, Human, Recombinant
Sentrin/SUMO-specific protease SENP2,Axam2,SMT3-spe... |
Human | E. coli |
SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway. | |||
TMPH-02284 |
USP26 Protein, Human, Recombinant (His)
|
Human | E. coli |
Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome. Deubiquitinates the androgen receptor and regulates the androgen receptor signaling pathway. | |||
TMPK-01542 |
HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human, MHC (His & Avi)
RMF,PSMB9,Proteasome chain 7,RING12,LMP2,LMP-2,MHC,... |
Human | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma... | |||
TMPH-02776 |
Mup2 Protein, Mouse, Recombinant (His)
|
Mouse | P. pastoris (Yeast) |
Mup2 Protein, Mouse, Recombinant (His) is expressed in Yeast. | |||
TMPJ-00919 |
FKBP2 Protein, Human, Recombinant (His)
also named 13 kDa FK506-binding protein,FK506-binding protei... |
Human | HEK293 Cells |
Peptidyl-prolyl cis-trans isomerase FKBP2(FKBP2 for short), also named 13 kDa FK506-binding protein, FK506-binding protein 2, Immunophilin FKBP13, Rotamase, is a endoplasmic reticulum peripheral membrane protein. It contains 1 PPIase FKBP-type domain and belongs to the FKBP-type PPIase family, FKBP2 subfamily which takes part in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP2 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 an... | |||
TMPH-02299 |
UGP2 Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. | |||
TMPH-01780 |
SCP2 Protein, Human, Recombinant (GST)
|
Human | E. coli |
SCP2 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 42.4 kDa and the accession number is P22307. | |||
TMPY-00018 |
METAP2 Protein, Human, Recombinant (His)
MAP2,MNPEP,p67eIF2,methionyl aminopeptidase 2,p67 |
Human | Baculovirus Insect Cells |
METAP2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.3 kDa and the accession number is A0A140VJE3. | |||
TMPH-01508 |
HABP2 Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII. May function as a tumor suppressor negatively regulat... | |||
TMPY-00499 |
TMP21 Protein, Human, Recombinant (mFc)
Tmp-21-I,p23,S31III125,TMP21,P24(... |
Human | HEK293 Cells |
TMED10 disrupts the complex formation between TGF-beta type I (also termed ALK5) and type II receptors (TbetaRII). Misexpression studies revealed that TMED10 attenuated TGF-beta-mediated signaling. A 20-amino acid-long region from Thr(91) to Glu(110) within the extracellular region of TMED10 was found to be crucial for TMED10 interaction with both ALK5 and TbetaRII. Synthetic peptides corresponding to this region inhibit both TGF-beta-induced Smad2 phosphorylation and Smad-dependent transcriptio... | |||
TMPY-03342 |
CRIP2 Protein, Human, Recombinant (His & GST)
CRIP,ESP1,CRP2,cysteine-rich protein 2 |
Human | Baculovirus Insect Cells |
CRIP2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 50.3 kDa and the accession number is P52943. | |||
TMPY-00992 |
ERAP2 Protein, Human, Recombinant (His)
L-RAP,endoplasmic reticulum aminopeptidase 2,FLJ23633,LRAP.E... |
Human | HEK293 Cells |
Leukocyte-derived arginine aminopeptidase (LRAP), also known as endoplasmic reticulum-aminopeptidase 2 (ERAP2), is the second identified aminopeptidase localized in the in the lumenal side of endoplasmic reticulum (ER) processing antigenic peptides presented to major histocompatibility complex (MHC) class I molecules. It is a 96-amino acid protein with significant homology to placental leucine aminopeptidase and adipocyte-derived leucine aminopeptidase. LRAP preferentially hydrolyz... | |||
TMPK-01498 |
HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Tetramer Protein, Human, MHC (His & Avi)
Proteasome chain 7,MHC,RING12,RMF,LMP2,LMP-2,PSMB9,... |
Human | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma... | |||
TMPK-00638 |
IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus, Recombinant (His)
IL1RL2,IL-1 Rrp2,IL-36R,IL-1 R6,IL1RRP2 |
Cynomolgus | HEK293 Cells |
IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.1 kDa and the accession number is G8F338. | |||
TMPK-01142 |
SFRP2 Protein, Human, Recombinant (His)
Sarp1,SARP-1,sFRP-2,AI851596,Sfrp2,Sdf5 |
Human | HEK293 Cells |
SFRP2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 32.4 kDa and the accession number is Q96HF1. | |||
TMPH-01293 |
ERP29 Protein, Human, Recombinant (GST)
|
Human | E. coli |
Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER. | |||
TMPH-01230 |
DIP2A Protein, Human, Recombinant (hFc)
DIP2 homolog A,Disco-interacting protein 2 homolog ... |
Human | HEK293 Cells |
Catalyzes the de novo synthesis of acetyl-CoA in vitro. Promotes acetylation of CTTN, possibly by providing the acetyl donor, ensuring correct dendritic spine morphology and synaptic transmission. Binds to follistatin-related protein FSTL1 and may act as a cell surface receptor for FSTL1, contributing to AKT activation and subsequent FSTL1-induced survival and function of endothelial cells and cardiac myocytes. | |||
TMPY-01773 |
CNDP2 Protein, Human, Recombinant (His)
CNDP dipeptidase 2 (metallopeptidase M20 family),CPGL,HEL-S-... |
Human | Baculovirus Insect Cells |
CNDP2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.2 kDa and the accession number is CAC69883.1. | |||
TMPY-01549 |
CRABP2 Protein, Human, Recombinant (His)
RBP6,cellular retinoic acid binding protein 2,CRABP-II |
Human | E. coli |
CRABP2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16.5 kDa and the accession number is P29373. | |||
TMPH-02986 |
Murine polyomavirus (MPyV) (strain Kilham) VP2 Protein (His)
|
MPyV | E. coli |
Murine polyomavirus (MPyV) (strain Kilham) VP2 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 41.4 kDa and the accession number is P24596. | |||
TMPH-02820 |
GP2 Protein, Mouse, Recombinant (His)
|
Mouse | P. pastoris (Yeast) |
GP2 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 59.0 kDa and the accession number is Q9D733. | |||
TMPH-01880 |
PARP2 Protein, Human, Recombinant (His)
|
Human | E. coli |
PARP2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 72.2 kDa and the accession number is Q9UGN5. | |||
TMPH-03039 |
ASP2 Protein, Necator americanus, Recombinant (His)
Secreted protein ASP-2,Ancylostoma secreted protein 2,AS... |
Necator americanus | E. coli |
ASP2 Protein, Necator americanus, Recombinant (His) is expressed in E. coli. | |||
TMPK-00582 |
MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated
MASP1P1,MAP19,sMap,MASP-2 |
Rat | E. coli |
MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.7 kDa and the accession number is A2VCV7. | |||
------------------------ 更多 ------------------------ |