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Targets Recommended: IRE1 Wee1 E1/E2/E3 Enzyme DprE1

194

抑制剂 & 化合物

19

天然产物

2

化合物库

1

TargetMol 试剂盒

106

重组蛋白

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Cat. No. Product Name
L8600 泛素化化合物库

210 compounds
210 种泛素化相关的小分子,用于高通量和高内涵筛选;
L8500 HIF-1化合物库

1336 compounds
1336 个HIF-1相关小分子的独特集合,可用于缺血性疾病、癌症等相关领域的药物开发和药理研究;

化合物库

泛素化化合物库
Cat.No: L8600
Compounds: 210
HIF-1化合物库
Cat.No: L8500
Compounds: 1336
Cat. No. Product Name Form Specificity Of Inhibition
CL0137 E1/E2/E3 Enzyme inhibitor kit

E1/E2/E3 Enzyme inhibitor kit

TargetMol 试剂盒

E1/E2/E3 Enzyme inhibitor kit
Cat.No: CL0137
Cat. No. Product Name Target Signaling Pathways
T39017 OVA-E1 peptide

OVA-E1 peptide

OVA-E1 peptide, a variant antagonist of SIINFEKL [OVA (257-264)], elicits comparable activation of the p38 and JNK cascades in both mutant and wild-type thymocytes.
T36770 11-deoxy Prostaglandin E1

11-deoxy Prostaglandin E1

11-deoxy Prostaglandin E1 是前列腺素 E1类似物,具有支气管扩张活性,可抑制组胺诱导的支气管收缩,引起离体豚鼠的气管条松弛。
T38665 OVA-E1 peptide TFA

OVA-E1 peptide TFA

p38 MAPK; JNK MAPK
OVA-E1 peptide TFA 在突变型和野生型胸腺细胞中都能同样地激活 p38 和 JNK 级联。
T36214 16,16-dimethyl Prostaglandin E1

16,16-dimethyl Prostaglandin E1

16,16-dimethyl Prostaglandin E1 是 PGE1 (T1626) 类似物,可诱导支气管收缩和血管平滑肌收缩,并抑制吲哚美辛诱导的细胞伸长。
T36726 6-keto Prostaglandin E1

6-keto Prostaglandin E1

6-keto Prostaglandin E1 是 PGE1 的生物活性衍生物,在抗血小板聚集和解聚作用方面发挥作用。
T36159 8-iso Prostaglandin E1

8-iso Prostaglandin E1

8-iso Prostaglandin E1 能引起犬肺静脉中的痉挛,还能够起到血管舒张作用。
T36775 13,14-dihydro Prostaglandin E1

13,14-dihydro Prostaglandin E1

13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively. 13,14-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 which has an IC50 value of 40 nM. Also, 13,14-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hyb...
T36219 1a,1b-dihomo Prostaglandin E1

1a,1b-dihomo Prostaglandin E1

1a,1b-dihomo Prostaglandin E1 是一类前列腺素化合物。
T37778 19(R)-hydroxy Prostaglandin E1

19(R)-hydroxy Prostaglandin E1

19(R)-hydroxy Prostaglandin E1 是 EP1 和 EP3 受体亚型的激动剂,并对平滑肌表现出收缩活性,也是灵长类动物精液中的主要前列腺素。
T36147 13,14-dihydro-15-keto Prostaglandin E1

13,14-dihydro-15-keto Prostaglandin E1

13,14-dihydro-15-keto Prostaglandin E1 可抑制 ADP 诱导的人离体富血小板血浆中的血小板聚集(IC50=14.8 μg/mL),也是 PGE1 代谢物。
T125156 Schidigerasaponin E1

Schidigerasaponin E1 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125156,CAS号为 266998-23-6。
T25269 Colistin A

Polymixin E1,Polymyxin E1,Colistin IV

Colistin A is an antibiotic generated by certain strains of the bacteria Paenibacillus polymyxa. Colistin is a mixture of the cyclic polypeptides colistin A and B and belongs to the class of polypeptide antibiotics known as polymyxins. Colistin is effecti
T24136 Heclin

E1/E2/E3 Enzyme Ubiquitination
Heclin 是一种 HECT E3 泛素连接酶抑制剂,通过抑制 Smurf2、Nedd4 和 WWP1 起作用,IC50 值分别为 6.8、6.3 和 6.9 μM。
T29907 Alprostadil sodium

PGE1 sodium salt,Prostaglandin E1 sodium

Alprostadil sodium 是一种前列腺素受体配体,对小鼠 EP1、EP2、EP3、EP4和 IP 的 Ki 值分别为 36、10、1.1、2.1 和 33 nM。它诱导血管舒张并抑制血小板聚集,可作为血管扩张剂用于外周血管疾病的研究。
T29908 Alprostadil ethyl ester

Prostaglandin E1 ethyl ester,PGE1 ethyl ester

Alprostadil ethyl ester is a biochemical used in the treatment of scleroderma.
T25362 Ecraprost

AS013,Circulase,AS 013,AS-013,Lipo-pro-prostaglandin E1

Ecraprost is used as a prodrug of prostaglandin E1.
T16901 SMIP004

Apoptosis; Others; E1/E2/E3 Enzyme Apoptosis; Others; Ubiquitination
SMIP004 是一种 SKP2 E3 连接酶抑制剂。 SMIP004 是人前列腺癌细胞的癌细胞特异性凋亡诱导剂。
T12261 NSC232003

E1/E2/E3 Enzyme Ubiquitination
NSC232003 是高效的UHRF1抑制剂,能够抑制 DNA 甲基化,并破坏 DNMT1/UHRF1 相互作用。
T16102 ML-792

E1/E2/E3 Enzyme Ubiquitination
ML-792 是特异性的小泛素样修饰物活化酶抑制剂。ML-792选择性抑制SAE/SUMO1和SAE/SUMO2,IC50分别为 3 和 11 nM,对 NAE/NEDD8 和 UAE/ubiquitin 抑制作用微弱,IC50分别为 32 μM 和 >100 μM。
T2158 Nutlin-3

Nutlin3

E1/E2/E3 Enzyme Ubiquitination
Nutlin-3 是一种 MDM2 拮抗剂,抑制 MDM2-p53 相互作用 ,Ki 为 90 nM,并激活 p53。
T16888 SJ-172550

Mdm2; E1/E2/E3 Enzyme Apoptosis; Ubiquitination
SJ-172550 是 MDMX 的小分子抑制剂,EC50为5 μM。
T8428 Subasumstat

TAK-981

E1/E2/E3 Enzyme Ubiquitination
Subasumstat (TAK-981) 是SUMOylation 酶联反应的选择性抑制剂,具有潜在的免疫激活和抗肿瘤特性。
T5374 NAcM-OPT

E1/E2/E3 Enzyme; NEDD8 Metabolism; Ubiquitination
NAcM-OPT 是口服活性、有效的 cullin neddylation 1 抑制剂,可以抑制 DCN1-UBE2M 相互作用。
T16699 PYZD-4409

Others; E1/E2/E3 Enzyme Others; Ubiquitination
PYZD-4409 是一种特异性 UBA1 抑制剂,IC50 为 20 μM。 PYZD-4409 在恶性细胞中诱导细胞死亡,并且对恶性细胞的细胞毒性优于对正常造血细胞的细胞毒性。
T5199 COH000

E1/E2/E3 Enzyme Ubiquitination
COH000 是不可逆的泛素样激活酶1 共价变构抑制剂,体外测得对 SUMO 化修饰的IC50=0.2 μM。
T13244 Ubiquitination-IN-1

Others Others
Ubiquitination-IN-1 是一种有效的泛素化和Cksl-Skp2蛋白互作抑制剂 (IC50=0.17 μM) 抑制剂,增加 p27 水平,可通过阻断肿瘤抑制因子的降解发挥作用。
T7379 2-D08

E1/E2/E3 Enzyme; TAM Receptor Tyrosine Kinase/Adaptors; Ubiquitination
2-D08是小泛素样修饰蛋白抑制剂。2-D08也能抑制 Axl,IC50=0.49 nM。
T3517 RO8994

Mdm2; E1/E2/E3 Enzyme; p53 Apoptosis; Ubiquitination
RO8994是一种高效且特异性的螺吲哚酮小分子 MDM2 抑制剂,MTT 增殖试验和HTRF 结合试验的IC50 为 20 nM 和 5 nM。
T7415 DKM 2-93

E1/E2/E3 Enzyme Ubiquitination
DKM 2-93是相对选择性 UBA5抑制剂,IC50=430 μM。
T7889 C25-140

Others; TNF; E1/E2/E3 Enzyme; NF-κB Apoptosis; NF-κB; Others; Ubiquitination
C25-140 是一种具有口服活性和一定选择性的 TRAF6-Ubc13相互作用抑制剂。它直接与 TRAF6 结合,阻断 TRAF6 和 Ubc13 的相互作用,降低 TRAF6 和 NF-κB 的活性,并与自身免疫对抗。
T9236 WSB1 Degrader 1

Others; E1/E2/E3 Enzyme Others; Ubiquitination
WSB1 Degrader 1 是具有口服活性的 WSB1降解剂,具有抗癌活性。
T6629 PYR-41

PYR41,PYR 41

Apoptosis; E1/E2/E3 Enzyme Apoptosis; Ubiquitination
PYR-41 是一种选择性,可透过细胞的泛素活化酶 E1抑制剂,IC50值小于10 μM。
T23371 SMER3

SMER 3

Others; Ligand for E3 Ligase Others; PROTAC
SMER3 是选择性的 Skp1-Cullin-F-box (SCF)Met30泛素连接酶抑制剂。SMER 3 通过抑制 SCFMet30来增强 Rapamycin 的生长抑制作用。
T3653 MX69

Mdm2; E1/E2/E3 Enzyme; IAP Apoptosis; Ubiquitination
MX69 是用于抗癌研究的一种MDM2/XIAP 抑制剂。
T6149 YH239-EE

Apoptosis; E1/E2/E3 Enzyme Apoptosis; Ubiquitination
YH239-EE 是 YH239 的乙酯,是 p53-MDM2 拮抗剂和凋亡诱导剂。
T10703 Mezigdomide

CC-92480

Apoptosis; E1/E2/E3 Enzyme; Molecular Glues Apoptosis; PROTAC; Ubiquitination
Mezigdomide (CC-92480) 是一种有效的、新型的、具有选择性的和具有活性的 cereblon E3 泛素连接酶调节剂 (CELMoD),常以分子胶的方式发挥作用。Mezigdomide 具有抗骨髓瘤活性。
T13349 WS-383

E1/E2/E3 Enzyme Ubiquitination
WS-383 是高效、选择性、可逆的DCN1-UBC12相互作用抑制剂,IC50为11 nM。它抑制 Cul3/1 的类泛素化修饰,引起 NRF2,p21和p27 的积累。
T11980 MD-224

Mdm2; E1/E2/E3 Enzyme; PROTACs Apoptosis; PROTAC; Ubiquitination
MD-224是一种基于蛋白水解靶向嵌合体(PROTAC)概念的高效、高效的MDM2降解剂,是一类新型抗癌剂。
T3317 SZL P1-41

Apoptosis; Others; E1/E2/E3 Enzyme Apoptosis; Others; Ubiquitination
SZL P1-41 是 Skp2 抑制剂,可以阻止 Skp2-Skp1 复合物的组装。 它选择性地抑制 Skp2 SCF E3 连接酶活性,还在体内外抑制 Skp2 介导的 p27 和 Akt 泛素化。 它通过触发细胞衰老和抑制糖酵解来抑制 Y 细胞和 Y 干细胞的存活,有抗肿瘤作用。
T8564 BC-1382

Others; E1/E2/E3 Enzyme Others; Ubiquitination
BC-1382 是E3泛素连接酶HECTD2抑制剂,能够特异性破坏 HECTD2/PIAS1 相互作用 (IC50≈ 5 nM)。BC-1382具有抗炎活性。
T3110 PRT4165

NSC600157,PRT 4165

BMI-1; Others; E1/E2/E3 Enzyme Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others; Ubiquitination
PRT4165 (NSC600157) 是有效的 PRC1介导 H2A 泛素化的抑制剂。
T4253 Skp2 Inhibitor C1

SKPin C1

Others; E1/E2/E3 Enzyme Others; Ubiquitination
Skp2 Inhibitor C1 (SKPin C1)(SKPin C1)是Skp2介导p27降解的特异性抑制剂。
T6254 Idasanutlin

RG7388,Ro 5503781,依达奴林

Mdm2; E1/E2/E3 Enzyme Apoptosis; Ubiquitination
Idasanutlin (Ro 5503781) 是一种有效且特异性的 p53-MDM2 抑制剂 ,IC50值为 6 nM。
T5555 Siremadlin

NVP-HDM 201

E1/E2/E3 Enzyme Ubiquitination
Siremadlin (NVP-HDM 201) 是一种有效的、可口服的、高度特异性的 p53-MDM2 相互作用抑制剂。
T3549 Avadomide

CC 122

Apoptosis; E1/E2/E3 Enzyme; Ligand for E3 Ligase Apoptosis; PROTAC; Ubiquitination
Avadomide (CC 122) 是口服有效的cereblon 调节剂,可以调节 cereblon E3 连接酶活性,诱导弥漫性大 B 细胞淋巴瘤细胞凋亡,具有抗肿瘤和免疫调节活性。
T16974 TAK-243

MLN7243

Apoptosis; E1/E2/E3 Enzyme; NF-κB Apoptosis; NF-κB; Ubiquitination
TAK-243 (MLN7243) 是一种泛素激活酶 UAE 的抑制剂 (IC50=1 nM),具有选择性。TAK-243 可阻断泛素结合,破坏单泛素信号传导以及整体蛋白质泛素化。TAK-243 具有抗肿瘤活性,可以促进细胞凋亡。
TQ0127 Navtemadlin

AMG232,CS-1300

Mdm2; E1/E2/E3 Enzyme Apoptosis; Ubiquitination
Navtemadlin (AMG232) 是一种有效的、选择性的、可口服的 p53-MDM2 相互作用抑制剂,IC50值为 0.6 nM。它以 0.045 nM 的 Kd 与 MDM2 结合。
T6965 RG7112

RG-7112,RG 7112,RO5045337

Mdm2; E1/E2/E3 Enzyme Apoptosis; Ubiquitination
RG7112 (RO5045337) 是一种口服生物可利用的选择性 p53-MDM2 抑制剂。
T2243 Serdemetan

JNJ-26854165,N-[2-(1H-吲哚-3-基)乙基]-N'-(4-吡啶基)-1,4-苯二胺

Apoptosis; Mdm2; E1/E2/E3 Enzyme; p53 Apoptosis; Ubiquitination
Serdemetan (JNJ-26854165) 是一种 HDM2泛素连接酶拮抗剂,能诱导 p53野生型细胞的早期凋亡。
TQ0231 NVP-CGM097

CGM097

Mdm2; E1/E2/E3 Enzyme Apoptosis; Ubiquitination
NVP-CGM097 (CGM097) 是一种选择性MDM2抑制剂,对hMDM2的IC50为 1.7 nM。

化合物

OVA-E1 peptide
Cat.No: T39017
Synonym: OVA-E1 peptide
Target:
11-deoxy Prostaglandin E1
Cat.No: T36770
Synonym: 11-deoxy Prostaglandin E1
Target:
OVA-E1 peptide TFA
Cat.No: T38665
Synonym: OVA-E1 peptide TFA
Target: p38 MAPK, JNK
16,16-dimethyl Prostaglandin E1
Cat.No: T36214
Synonym: 16,16-dimethyl Prostaglandin E1
Target:
6-keto Prostaglandin E1
Cat.No: T36726
Synonym: 6-keto Prostaglandin E1
Target:
8-iso Prostaglandin E1
Cat.No: T36159
Synonym: 8-iso Prostaglandin E1
Target:
13,14-dihydro Prostaglandin E1
Cat.No: T36775
Synonym: 13,14-dihydro Prostaglandin E1
Target:
1a,1b-dihomo Prostaglandin E1
Cat.No: T36219
Synonym: 1a,1b-dihomo Prostaglandin E1
Target:
19(R)-hydroxy Prostaglandin E1
Cat.No: T37778
Synonym: 19(R)-hydroxy Prostaglandin E1
Target:
13,14-dihydro-15-keto Prostaglandin E1
Cat.No: T36147
Synonym: 13,14-dihydro-15-keto Prostaglandin E1
Target:
Schidigerasaponin E1
Cat.No: T125156
Synonym:
Target:
Colistin A
Cat.No: T25269
Synonym: Polymixin E1,Polymyxin E1,Colistin IV
Target:
Heclin
Cat.No: T24136
Synonym:
Target: E1/E2/E3 Enzyme
Alprostadil sodium
Cat.No: T29907
Synonym: PGE1 sodium salt,Prostaglandin E1 sodium
Target:
Alprostadil ethyl ester
Cat.No: T29908
Synonym: Prostaglandin E1 ethyl ester,PGE1 ethyl ester
Target:
Ecraprost
Cat.No: T25362
Synonym: AS013,Circulase,AS 013,AS-013,Lipo-pro-prostaglandin E1
Target:
SMIP004
Cat.No: T16901
Synonym:
Target: Apoptosis, Others, E1/E2/E3 Enzyme
NSC232003
Cat.No: T12261
Synonym:
Target: E1/E2/E3 Enzyme
ML-792
Cat.No: T16102
Synonym:
Target: E1/E2/E3 Enzyme
Nutlin-3
Cat.No: T2158
Synonym: Nutlin3
Target: E1/E2/E3 Enzyme
SJ-172550
Cat.No: T16888
Synonym:
Target: Mdm2, E1/E2/E3 Enzyme
Subasumstat
Cat.No: T8428
Synonym: TAK-981
Target: E1/E2/E3 Enzyme
NAcM-OPT
Cat.No: T5374
Synonym:
Target: E1/E2/E3 Enzyme, NEDD8
PYZD-4409
Cat.No: T16699
Synonym:
Target: Others, E1/E2/E3 Enzyme
COH000
Cat.No: T5199
Synonym:
Target: E1/E2/E3 Enzyme
Ubiquitination-IN-1
Cat.No: T13244
Synonym:
Target: Others
2-D08
Cat.No: T7379
Synonym:
Target: E1/E2/E3 Enzyme, TAM Receptor
RO8994
Cat.No: T3517
Synonym:
Target: Mdm2, E1/E2/E3 Enzyme, p53
DKM 2-93
Cat.No: T7415
Synonym:
Target: E1/E2/E3 Enzyme
C25-140
Cat.No: T7889
Synonym:
Target: Others, TNF, E1/E2/E3 Enzyme, NF-κB
WSB1 Degrader 1
Cat.No: T9236
Synonym:
Target: Others, E1/E2/E3 Enzyme
PYR-41
Cat.No: T6629
Synonym: PYR41,PYR 41
Target: Apoptosis, E1/E2/E3 Enzyme
SMER3
Cat.No: T23371
Synonym: SMER 3
Target: Others, Ligand for E3 Ligase
MX69
Cat.No: T3653
Synonym:
Target: Mdm2, E1/E2/E3 Enzyme, IAP
YH239-EE
Cat.No: T6149
Synonym:
Target: Apoptosis, E1/E2/E3 Enzyme
Mezigdomide
Cat.No: T10703
Synonym: CC-92480
Target: Apoptosis, E1/E2/E3 Enzyme, Molecular Glues
WS-383
Cat.No: T13349
Synonym:
Target: E1/E2/E3 Enzyme
MD-224
Cat.No: T11980
Synonym:
Target: Mdm2, E1/E2/E3 Enzyme, PROTACs
SZL P1-41
Cat.No: T3317
Synonym:
Target: Apoptosis, Others, E1/E2/E3 Enzyme
BC-1382
Cat.No: T8564
Synonym:
Target: Others, E1/E2/E3 Enzyme
PRT4165
Cat.No: T3110
Synonym: NSC600157,PRT 4165
Target: BMI-1, Others, E1/E2/E3 Enzyme
Skp2 Inhibitor C1
Cat.No: T4253
Synonym: SKPin C1
Target: Others, E1/E2/E3 Enzyme
Idasanutlin
Cat.No: T6254
Synonym: RG7388,Ro 5503781,依达奴林
Target: Mdm2, E1/E2/E3 Enzyme
Siremadlin
Cat.No: T5555
Synonym: NVP-HDM 201
Target: E1/E2/E3 Enzyme
Avadomide
Cat.No: T3549
Synonym: CC 122
Target: Apoptosis, E1/E2/E3 Enzyme, Ligand for E3 Ligase
TAK-243
Cat.No: T16974
Synonym: MLN7243
Target: Apoptosis, E1/E2/E3 Enzyme, NF-κB
Navtemadlin
Cat.No: TQ0127
Synonym: AMG232,CS-1300
Target: Mdm2, E1/E2/E3 Enzyme
RG7112
Cat.No: T6965
Synonym: RG-7112,RG 7112,RO5045337
Target: Mdm2, E1/E2/E3 Enzyme
Serdemetan
Cat.No: T2243
Synonym: JNJ-26854165,N-[2-(1H-吲哚-3-基)乙基]-N'-(4-吡啶基)-1,4-苯二胺
Target: Apoptosis, Mdm2, E1/E2/E3 Enzyme, p53
NVP-CGM097
Cat.No: TQ0231
Synonym: CGM097
Target: Mdm2, E1/E2/E3 Enzyme
Cat. No. Product Name Target Signaling Pathways
T12090 Mogroside I E1

罗汉果苷 I E1

Others Others
Mogroside I E1 是三萜糖苷,是非糖类甜味剂。其中 Mogroside 的甜度比蔗糖高,具有抗氧化,抗糖尿病和抗癌特性。
T1626 Prostaglandin E1

前列地尔,PGE1,列腺素E1,Alprostadil

Endogenous Metabolite; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism
Prostaglandin E1 (Alprostadil) 是一种前列腺素受体配体,对小鼠 EP1、EP2、EP3、EP4和 IP 的 Ki 值分别为 36、10、1.1、2.1 和 33 nM。它诱导血管舒张并抑制血小板聚集,可作为血管扩张剂用于外周血管疾病的研究。
T16733 Resolvin E1

RvE1

Others Others
Resolvin E1 is an effective endogenous pro-resolving mediator of inflammation. Resolvin E1 has unique counterregulatory actions that inhibit PMN transendothelial migration. Resolvin E1 also acts as an effective inhibitor of leukocyte infiltration, dendrit
T80996 Theasaponin E1

Theasaponin E1,一种可从茶籽分离的茶皂苷,对人肿瘤细胞系K562和HL60展示了抗肿瘤潜能。此外,Theasaponin E1具备醌还原酶(QR)诱导活性,有助于作为抗癌预防药物的研究。
T83902 Polymyxin E1 sulfate

Colistin A sulfate

Polymyxin E1,是一种肽类抗生素,也是原初从B. polymyxa分离得到的阳离子脂肽抗生素colistin的主要成分。对P. aeruginosa和E. coli具有活性(MICs分别为2和0.8 µg/ml)。
T4S0181 Hinokiflavone

日本扁柏黄酮,扁柏双黄酮

MMP; BCL; E1/E2/E3 Enzyme Apoptosis; Proteases/Proteasome; Ubiquitination
Hinokiflavone 是pre-mRNA 剪接活性的新型调节剂,通过抑制剪接体装配来阻止pre-mRNA 底物的剪接,特别是阻止 B complex 的形成。它是SUMO protease 蛋白酶抑制剂,能够抑制前哨蛋白特异性蛋白酶 1 的活性。
TN1124 Neoeriocitrin

AChE Neuroscience
Neoeriocitrin 是一种有效的乙酰胆碱酯酶抑制剂,分离于自百日草,在 MC3T3-E1 中显示出对增殖和成骨分化的活性。
T9352 hydrocotarnine

Others Others
hydrocotarnine 是 Cbl 的抑制剂。
T4036 Solasodine

Solancarpidine,Purapuridine,澳洲茄铵,Solasodin

Apoptosis; Others; E1/E2/E3 Enzyme; Antifungal Apoptosis; Microbiology/Virology; Others; Ubiquitination
Solasodine (Purapuridine) 是存在于茄科植物中的一种类固醇生物碱。它具有神经保护、降压、抗真菌、抗癌、抗动脉粥样硬化、抗雄激素和抗炎活性。
T2947 Indole-3-carbinol

吲哚-3-甲醇,I3C,3-Indolemethanol,3-吲哚甲醇,Indole-3-Methanol

E1/E2/E3 Enzyme; NF-κB; Aryl Hydrocarbon Receptor; Endogenous Metabolite; p53 Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; Ubiquitination
Indole-3-carbinol (I3C) 是樟子松中的一种天然产物,是可口服的硫代葡萄糖苷葡糖苷酶裂解产物。它是芳烃受体 (AhR) 的激动剂,可抑制 NF-κB 和 IκBα 激酶活化。
T6S2123 Ginkgolic Acid

Romanicardic acid,Ginkgolic acid I,Ginkgolic acid (15:1),银杏酸C15:1,银杏酸,Ginkgolic acid C15:1

Others; E1/E2/E3 Enzyme Others; Ubiquitination
Ginkgolic Acid (Romanicardic acid) 是一种天然化合物, 在体外实验中抑制SUMOylation,IC50=3.0 μM。
T21518 Colistin methanesulfonate sodium salt

粘杆菌素甲基磺酸钠,Colistin Methanesulfonate (sodium salt)

Cell wall; Antibacterial Immunology/Inflammation; Microbiology/Virology
Colistin methanesulfonate sodium salt (Colistimethate Sodium) 是一种来自 Bacillus colistinus 的环状多肽抗生素,由多粘菌素 E1 和 E2 组成。
T1245 Colistin sulfate

Colistin sulfate (1066-17-7 free base),Polymixin E Sulfate,Polymyxin E Sulfate,硫酸粘杆菌素

Cell wall; Antibacterial; Antibiotic; Autophagy Autophagy; Immunology/Inflammation; Microbiology/Virology
Colistin sulfate (Colistin sulfate (1066-17-7 free base)) 是抑制革兰氏阴性细菌的一种多肽抗生素,与革兰氏阴性细菌的外细胞膜中的脂多糖和磷脂结合起作用。
T5S2129 Sciadopitysin

TNF; NF-κB Apoptosis; NF-κB
Sciadopitysin 是一种双黄酮类化合物,来自银杏叶片中。它通过抑制NF-κB 活化并降低c-Fos 和NFATc1的表达来抑制 RANKL 诱导的破骨细胞生成和骨丢失。
TN6926 Paeonoside

Others Others
Paeonoside 发现与P. suffruticosa 中,具有生物活性,可以促进成骨细胞分化过程中的伤口愈合和迁移。Paeonoside 具有一定的抗糖尿病活性,可防止脓毒症和败血症引起的死亡。Paeonoside 对 MC3T3-E1细胞的前成骨细胞没有细胞毒性作用,以剂量依赖性的方式显著恢复伤口区域并促进细胞迁移和促进碱性磷酸酶(ALP)染色及其活性。
T4S1943 Kirenol

奇壬醇,奇任醇,Kirel

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
Kirenol (Kirel) 是分离自 Siegesbeckia orientalis 中的,具有抗氧化、抗炎、抗过敏、抗关节炎活性,可用于缓解疼痛的研究。
T6S1559 Aurantio-obtusin

Others Others
Aurantio-obtusin 是从决明子中分离出的蒽醌类化合物,具有抗炎、抗凝血、抗氧化、抗高血压的活性。它能抑制 IgE 介导的肥大细胞和过敏模型中的过敏反应,具有研究过敏相关疾病的潜力。在大鼠中,它通过内皮细胞 PI3K/AKT/ eNOS 依赖信号通路放松全身动脉,是潜在的新型血管扩张剂。
TQ0262 Dihomo-γ-linolenic acid

Diroleuton,顺式-8,11,14-二十烷三烯酸甲酯,all-cis-8,11,14-Eicosatrienoic acid,Ro 12-1989

Others Others
Ro 12-1989 can be converted into prostaglandin E1 (PGE1). Ro 12-1989 competes with arachidonic acid for COX and lipoxygenase, inhibiting the production of arachidonic acid's eicosanoids.
TN3753 Dalbergioidin

Tyrosinase; ROS; Akt; PI3K; TGF-beta/Smad Cytoskeletal Signaling; Immunology/Inflammation; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces bikiniensis that has commonly been used as an indicator organism. Dalbergioidin protects MC3T3-E1 osteoblastic cells against H2O2-induced cell damage through activation of the PI3K/AKT/SMAD1 pathway, suggests that it may be useful in bone metabolism diseases, particularly osteoporosis. Dalbergioidin also ameliorates doxorubicin-induced ...

天然产物

Mogroside I E1
Cat.No: T12090
Synonym: 罗汉果苷 I E1
Target: Others
Prostaglandin E1
Cat.No: T1626
Synonym: 前列地尔,PGE1,列腺素E1,Alprostadil
Target: Endogenous Metabolite, Prostaglandin Receptor
Resolvin E1
Cat.No: T16733
Synonym: RvE1
Target: Others
Theasaponin E1
Cat.No: T80996
Synonym:
Target:
Polymyxin E1 sulfate
Cat.No: T83902
Synonym: Colistin A sulfate
Target:
Hinokiflavone
Cat.No: T4S0181
Synonym: 日本扁柏黄酮,扁柏双黄酮
Target: MMP, BCL, E1/E2/E3 Enzyme
Neoeriocitrin
Cat.No: TN1124
Synonym:
Target: AChE
hydrocotarnine
Cat.No: T9352
Synonym:
Target: Others
Solasodine
Cat.No: T4036
Synonym: Solancarpidine,Purapuridine,澳洲茄铵,Solasodin
Target: Apoptosis, Others, E1/E2/E3 Enzyme, Antifungal
Indole-3-carbinol
Cat.No: T2947
Synonym: 吲哚-3-甲醇,I3C,3-Indolemethanol,3-吲哚甲醇,Indole-3-Methanol
Target: E1/E2/E3 Enzyme, NF-κB, Aryl Hydrocarbon Receptor, Endogenous Metabolite, p53
Ginkgolic Acid
Cat.No: T6S2123
Synonym: Romanicardic acid,Ginkgolic acid I,Ginkgolic acid (15:1),银杏酸C15:1,银杏酸,Ginkgolic acid C15:1
Target: Others, E1/E2/E3 Enzyme
Colistin methanesulfonate sodium salt
Cat.No: T21518
Synonym: 粘杆菌素甲基磺酸钠,Colistin Methanesulfonate (sodium salt)
Target: Cell wall, Antibacterial
Colistin sulfate
Cat.No: T1245
Synonym: Colistin sulfate (1066-17-7 free base),Polymixin E Sulfate,Polymyxin E Sulfate,硫酸粘杆菌素
Target: Cell wall, Antibacterial, Antibiotic, Autophagy
Sciadopitysin
Cat.No: T5S2129
Synonym:
Target: TNF, NF-κB
Paeonoside
Cat.No: TN6926
Synonym:
Target: Others
Kirenol
Cat.No: T4S1943
Synonym: 奇壬醇,奇任醇,Kirel
Target: Wnt/beta-catenin
Aurantio-obtusin
Cat.No: T6S1559
Synonym:
Target: Others
Dihomo-γ-linolenic acid
Cat.No: TQ0262
Synonym: Diroleuton,顺式-8,11,14-二十烷三烯酸甲酯,all-cis-8,11,14-Eicosatrienoic acid,Ro 12-1989
Target: Others
Dalbergioidin
Cat.No: TN3753
Synonym:
Target: Tyrosinase, ROS, Akt, PI3K, TGF-beta/Smad
Cat. No. Product Name Species Expression System
TMPY-04135 Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His)

HCV-E1

HCV HEK293 Cells
Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.7 kDa and the accession number is AAC15725.1.
TMPJ-00625 Serpin E1 Protein, Mouse, Recombinant (His)

Pai1,Planh1,Plasminogen activator inhibitor 1,Serpin E1<...

Mouse HEK293 Cells
Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis.
TMPH-00597 Colicin-E1 Protein, E. coli, Recombinant (His & Myc)

cea,Colicin-E1

E. coli E. coli
This colicin is a channel-forming colicin. This class of transmembrane toxins depolarize the cytoplasmic membrane, leading to dissipation of cellular energy.; Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.
TMPH-00596 Colicin-E1 Protein, E. coli, Recombinant (Cell-Free, His & Myc)

Colicin-E1,cea

E. coli E. coli
This colicin is a channel-forming colicin. This class of transmembrane toxins depolarize the cytoplasmic membrane, leading to dissipation of cellular energy.; Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.
TMPY-02777 Cyclin E Protein, Human, Recombinant (His & GST)

cyclin E1,CCNE

Human Baculovirus Insect Cells
Cyclin E Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75 kDa and the accession number is P24864-1.
TMPY-01550 Cyclin E Protein, Human, Recombinant (His)

cyclin E1,CCNE

Human Baculovirus Insect Cells
Cyclin E Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49.3 kDa and the accession number is P24864-1.
TMPY-03535 Cyclin E Protein, Mouse, Recombinant (His & GST)

cyclin E1,AW538188,CycE1

Mouse Baculovirus Insect Cells
Cyclin E Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 74.8 kDa and the accession number is AAH62152.1.
TMPY-01693 Butyrylcholinesterase Protein, Human, Recombinant (His)

CHE1,E1,butyrylcholinesterase,CHE2

Human HEK293 Cells
Butyrylcholinesterase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.5 kDa and the accession number is P06276.
TMPY-06748 UBA6 Protein, Human, Recombinant (GST)

ubiquitin-like modifier activating enzyme 6,UBE1L2,...

Human Baculovirus Insect Cells
UBA6 (Ubiquitin Like Modifier Activating Enzyme 6) is a Protein Coding gene. The UBA6 gene, located on 4q13.2, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. Uba6 is a homolog of the ubiquitin-activating enzyme, Uba1, and activates two ubiquitin-like proteins (UBLs), ubiquitin and FAT10. UBA6 is an alternative enzyme for ubiquitin activation in vertebrates that plays a pivotal role in early mouse development. UBA6 is widely expressed in the lymph n...
TMPY-01595 PCBP1 Protein, Human, Recombinant (His)

HNRPE1,hnRNP-E1,HEL-S-85,HNRPX,poly(rC) bi...

Human E. coli
Poly(rC)-binding protein 1, also known as Heterogeneous nuclear ribonucleoprotein E1, Alpha-CP1, Nucleic acid-binding protein SUB2.3 and PCBP1, is a family member of heterogeneous nuclear ribonucleoproteins (hnRNPs) that belong to RNA-binding proteins and bear three KH domains. PCBP1 is loosely bound in the nucleus. It may shuttle between the nucleus and the cytoplasm. It is abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in pr...
TMPK-01168 LOX-1 Protein, Mouse, Recombinant (His)

LOXIN,LOX-1,CLEC8A,Ox-LDL receptor 1,SLOX1,LOX1,SCARE1

Mouse HEK293 Cells
LOX-1 is a transmembrane glycoprotein that binds to and internalizes ox-LDL.LOX-1 gene deletion in mice and anti-LOX-1 therapy has been shown to decrease inflammation, oxidative stress and atherosclerosis. LOX-1 deletion also results in damage from ischemia, making LOX-1 a promising target of therapy for atherosclerosis and related disorders. In this article we focus on the different mechanisms for regulation, signaling and the various effects of LOX-1 in contributing to atherosclerosis.
TMPY-02840 Ubiquitin Activating Enzyme E1/UBA1 Protein, Human, Recombinant (His & GST)

UBE1,ubiquitin-like modifier activating enzyme 1,UB...

Human Baculovirus Insect Cells
UBE1, also known as UBA1, belongs to the ubiquitin-activating E1 family. UBE1 gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. UBE1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. It also catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation by first adenylating its C-terminal glycine residue w...
TMPH-00850 OGDC-E1 Protein, Human, Recombinant (His & SUMO)

Human E. coli
OGDC-E1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 59.1 kDa and the accession number is Q02218.
TMPY-00015 Influenza A H10N8 (A/duck/Guangdong/E1/2012) Hemagglutinin/HA1 Protein (His)

Harvey rat sarcoma viral oncogene homolog

H10N8 HEK293 Cells
Influenza A H10N8 (A/duck/Guangdong/E1/2012) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37 kDa and the accession number is I6PXD4.
TMPY-01583 ALDH1A1 Protein, Human, Recombinant (His)

ALDH11,ALDC,PUMB1,ALDH-E1,HEL-S-53e,HEL-9,aldehyde ...

Human E. coli
Aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), also known as Aldehyde dehydrogenase 1 (ALDH1), or Retinaldehyde Dehydrogenase 1 (RALDH1), is an enzyme that is expressed at high levels in stem cells and that has been suggested to regulate stem cell function. The retinaldehyde dehydrogenase (RALDH) subfamily of ALDHs, composed of ALDH1A1, ALDH1A2, ALDH1A3, and ALDH8A1, regulate development by catalyzing retinoic acid biosynthesis. The ALDH1A1 protein belongs to the aldehyde dehydrogenases f...
TMPH-01829 Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E1 (His)

HPV 11 E. coli
Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E1 (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.1 kDa and the accession number is P04014.
TMPJ-00914 YY1 Protein, Human, Recombinant (His)

NF-E1,Transcriptional repressor protein YY1,Yin and...

Human E. coli
Transcriptional repressor protein YY1(YY1)contains 4 C2H2-type zinc fingers and belongs to the YY transcription factor family. Multifunctional transcription factor exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. The effect on transcription regulation of the protein is depending upon the context in which it binds and diverse mechanisms of action include direct activation or repression, indirect acti...
TMPJ-01324 UBA5 Protein, Human, Recombinant (His)

Ubiquitin-like modifier-activating enzyme 5,UBE1DC1...

Human E. coli
UBA5 is a member of the ubiquitin-activating E1 family and UBA5 subfamily. Ubiquitin and ubiquitin-like proteins are recognized as covalently conjugated to various cellular substrates by a three-step enzymatic pathway. The ubiquitin-activating enzyme (E1) has a vital role in the first step of ubiquitination pathway to activate ubiquitin or ubiquitin-like proteins. UBA5 activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy th...
TMPY-00019 Influenza A H10N8 (A/duck/Guangdong/E1/2012) Neuraminidase/NA Protein (His)

NA Protein,Neuraminidase

H10N8 Baculovirus Insect Cells
Influenza A H10N8 (A/duck/Guangdong/E1/2012) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.2 kDa and the accession number is I6PU08.
TMPY-04413 IRE1 Protein, Human, Recombinant (aa 465-977, His & GST)

hIRE1p,endoplasmic reticulum to nucleus signaling 1...

Human Baculovirus Insect Cells
IRE1 Protein, Human, Recombinant (aa 465-977, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 86 kDa and the accession number is O75460-1.
TMPY-04753 IRE1 Protein, Human, Recombinant (aa 465-977)

hIRE1p,endoplasmic reticulum to nucleus signaling 1...

Human Baculovirus Insect Cells
IRE1 Protein, Human, Recombinant (aa 465-977) is expressed in Baculovirus insect cells. The predicted molecular weight is 58.3 kDa and the accession number is O75460-1.
TMPY-03441 SAE1 Protein, Human, Recombinant

SUA1,SUMO1 activating enzyme subunit 1,HSPC140,UBLE1

Human Baculovirus Insect Cells
SAE1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 38.6 kDa and the accession number is Q9UBE0.
TMPY-06417 SARS-CoV-2 Spike S1 Protein (T19R & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (T19R & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.22 kDa and the accession number is A0A6G7K2L4.
TMPY-06271 SARS-CoV-2 Spike S1+S2 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R & Q1071H, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R & Q1071H, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.51 kDa and the accession number is A0A6G7K2L4.
TMPY-03612 PSME1 Protein, Human, Recombinant (His)

proteasome (prosome, macropain) activator subunit 1 (PA28 al...

Human E. coli
PA28A, also known as PSME1, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 1 non-ATPase subunit...
TMPH-00899 Human adenovirus C serotype 5 E1B 55 kDa protein (His & Myc)

HAdV-5 E. coli
Human adenovirus C serotype 5 E1B 55 kDa protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 62.4 kDa and the accession number is P03243.
TMPY-06252 SARS-CoV-2 Spike S1 Protein (T19R & G142D & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (T19R & G142D & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.27 kDa and the accession number is A0A6G7K2L4.
TMPH-00516 StxA2 Protein, Enterobacteria phage 933W, Recombinant (E189K, His & Myc)

Enterobacteria phage 933W E. coli
The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits.
TMPY-02337 Influenza A H3N2 Neuraminidase/NA Protein (E119V)

NA Protein

H3N2 HEK293 Cells
Influenza A H3N2 Neuraminidase/NA Protein (E119V) is expressed in HEK293 mammalian cells. The accession number is C0LU95.
TMPY-06224 SARS-CoV-2 Spike S1+S2 Protein (E154K & L452R & E484Q & D614G & P681R & E1072K & K1073R, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (E154K & L452R & E484Q & D614G & P681R & E1072K & K1073R, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.5 kDa and the accession number is A0A6G7K2L4.
TMPJ-00815 FBPase1 Protein, Human, Recombinant (His, E. coli)

6-Bisphosphate 1-Phosphohydrolase 1,FBP1,FBP,FBPase 1,D-Fruc...

Human E. coli
Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young chi...
TMPY-00652 BACE1 Protein, Human, Recombinant

BACE,HSPC104,β-site APP-cleaving enzyme 1,beta-site APP-clea...

Human HEK293 Cells
BACE1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 49 kDa and the accession number is A0A024R3D7.
TMPK-01335 3CLpro/3C-like Protease Protein (E166V), SARS-COV-2, Recombinant

M Proteinase,Mpro,3CL Protease,3CL-Mpro

SARS-CoV-2 E. coli
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (E166V), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.80 kDa and the accession number is YP_009725301.1.
TMPY-04467 NME1 Protein, Human, Recombinant (His)

NME/NM23 nucleoside diphosphate kinase 1,NB,NDPK-A,NM23-H1,N...

Human E. coli
NME1, also known as Nucleoside Diphosphate Kinase A (NDK-A), or NM23-H1, belongs to the NDK family. NM23-H1 is known to have a metastasis suppressive activity in many tumor cells. Recent studies have shown that the interacting proteins with NM23-H1 which mediate cell proliferation, may act as modulators of the metastasis suppressor activity. The interacting proteins with NM23-H1 can be classified into 3 groups. The first group of proteins can be classified as upstream kinases of NM23-H1 such as ...
TMPY-02983 LYVE1 Protein, Mouse, Recombinant (hFc)

1200012G08Rik,Lyve-1,lymphatic vessel endothelial hyaluronan...

Mouse HEK293 Cells
LYVE1, also known as LYVE-1, is a type I integral membrane glycoprotein. It contains 1 Link domain and is mainly expressed in endothelial cells lining lymphatic vessels. LYVE1 acts as a receptor and binds to both soluble and immobilized hyaluronan. It may function in lymphatic hyaluronan transport and have a role in tumor metastasis. LYVE1 also is a cell surface receptor on lymphatic endothelial cells that can be used as a lymphatic endothelial cell marker, and sort these cells for experimental ...
TMPY-03265 CPNE1 Protein, Human, Recombinant (SUMO)

CPN1,copine I,COPN1

Human Baculovirus Insect Cells
CPNE1 Protein, Human, Recombinant (SUMO) is expressed in Baculovirus insect cells with SUMO tag. The predicted molecular weight is 72.7 kDa and the accession number is Q99829.
TMPY-04450 CDK1 & CCNE1 Heterodimer Protein, Human, Recombinant (His & GST)

P34CDC2 & CCNE1,CDC2,CDKN1,CDK1,CCNE,CDC28A

Human Baculovirus Insect Cells
CDK1 & CCNE1 Heterodimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 109.7 kDa and the accession number is NP_001777.1&NP_001229.1.
TMPY-01660 SULT1E1 Protein, Human, Recombinant (His)

ST1E1,EST,sulfotransferase family 1E member 1,EST-1...

Human E. coli
Estrogen sulfotransferase, also known as Sulfotransferase, estrogen-preferring, Sulfotransferase 1E1, SULT1E1 and ST1E1, is a cytoplasm enzyme that belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SULT1E1 may control the level of the estrogen receptor by sulfurylating free estradio...
TMPY-03449 CPNE1 Protein, Human, Recombinant

CPN1,COPN1,copine I

Human Baculovirus Insect Cells
CPNE1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 59.2 kDa and the accession number is Q99829.
TMPY-06443 SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His)

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.29 kDa and the accession number is YP_009724390.1.
TMPY-03062 SAE1 Protein, Human, Recombinant (His & GST)

UBLE1A,SUMO1 activating enzyme subunit 1,AOS1,HSPC1...

Human Baculovirus Insect Cells
SAE1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 66.3 kDa and the accession number is Q9UBE0.
TMPK-01347 3CLpro/3C-like Protease Protein (E166A), SARS-COV-2, Recombinant

3CL-Mpro,3CL Protease,M Proteinase,Mpro

SARS-CoV-2 E. coli
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (E166A), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 34.4kDa and the accession number is YP_009725301.1.
TMPH-02618 CYP2E1 Protein, Mouse, Recombinant (His)

Cyp2e1,Cytochrome P450 2E1,Cytochrome P450...

Mouse E. coli
A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be invo...
TMPH-03458 STE11 Protein, S. cerevisiae, Recombinant

Saccharomyces cerevisiae E. coli
Serine/threonine protein kinase required for cell-type-specific transcription and signal transduction in yeast. It is thought that it phosphorylates the STE7 protein kinase which itself, phosphorylates the FUS3 and or KSS1 kinases. STE11 Protein, S. cerevisiae, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.5 kDa and the accession number is P23561.
TMPJ-00879 HOXB4 Protein, Human,Recombinant (L175D, E176K, E178K, His)

Homeobox protein Hox-2.6,HOX2F,HOXB4,Homeobox protein Hox-2F...

Human E. coli
Homeobox B4 (HOXB4) is encoded by the HOXB4 gene which is a member of the the class I homeobox (HOX) gene family and encodes a nuclear protein with a homeobox DNA-binding domain. These genes are master control regulators of developmental programs including embryonic and adult hematopoiesis. Multiple HOX genes, including HOXB4, are highly expressed in the hematopoietic stem cells (HSC) compartment. HOXB4 gene can act in opposite ways when expressed by different cells, promoting the proliferation ...
TMPH-01213 DNASE1L3 Protein, Human, Recombinant (His)

DNase I homolog protein DHP2,DNAS1L3,DNase I-like 3,Deoxyrib...

Human Baculovirus Insect Cells
Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA. Acts in internucleosomal DNA fragmentation (INDF) during apoptosis and necrosis. The role in apoptosis includes myogenic and neuronal differentiation, and BCR-mediated clonal deletion of self-reactive B cells. Is active on chromatin in apoptotic cell-derived membrane-coated mic...
TMPH-00900 Human adenovirus C serotype 5 Early E1A protein (His & SUMO)

HAdV-5 E. coli
Human adenovirus C serotype 5 Early E1A protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.8 kDa and the accession number is P03255.
TMPY-06292 SARS-CoV-2 Spike S1+S2 Protein (D614G & E154K & E484Q & G142D & H1101D & L452R & P681R & Q1071H, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (D614G & E154K & E484Q & G142D & H1101D & L452R & P681R & Q1071H, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.48 kDa and the accession number is A0A6G7K2L4.
TMPH-01212 DNASE1L3 Protein, Human, Recombinant (His & Myc)

LSD,Liver and spleen DNase,Deoxyribonuclease I-like 3,DNAS1L...

Human E. coli
Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA. Acts in internucleosomal DNA fragmentation (INDF) during apoptosis and necrosis. The role in apoptosis includes myogenic and neuronal differentiation, and BCR-mediated clonal deletion of self-reactive B cells. Is active on chromatin in apoptotic cell-derived membrane-coated mic...
TMPH-01214 DNASE1L3 Protein, Human, Recombinant

DHP2,Deoxyribonuclease I-like 3,Deoxyribonuclease gamma,DNas...

Human E. coli
Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA. Acts in internucleosomal DNA fragmentation (INDF) during apoptosis and necrosis. The role in apoptosis includes myogenic and neuronal differentiation, and BCR-mediated clonal deletion of self-reactive B cells. Is active on chromatin in apoptotic cell-derived membrane-coated mic...
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重组蛋白

Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His)
Cat.No: TMPY-04135
Species: HCV
Expression System: HEK293 Cells
Serpin E1 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00625
Species: Mouse
Expression System: HEK293 Cells
Colicin-E1 Protein, E. coli, Recombinant (His & Myc)
Cat.No: TMPH-00597
Species: E. coli
Expression System: E. coli
Colicin-E1 Protein, E. coli, Recombinant (Cell-Free, His & Myc)
Cat.No: TMPH-00596
Species: E. coli
Expression System: E. coli
Cyclin E Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-02777
Species: Human
Expression System: Baculovirus Insect Cells
Cyclin E Protein, Human, Recombinant (His)
Cat.No: TMPY-01550
Species: Human
Expression System: Baculovirus Insect Cells
Cyclin E Protein, Mouse, Recombinant (His & GST)
Cat.No: TMPY-03535
Species: Mouse
Expression System: Baculovirus Insect Cells
Butyrylcholinesterase Protein, Human, Recombinant (His)
Cat.No: TMPY-01693
Species: Human
Expression System: HEK293 Cells
UBA6 Protein, Human, Recombinant (GST)
Cat.No: TMPY-06748
Species: Human
Expression System: Baculovirus Insect Cells
PCBP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01595
Species: Human
Expression System: E. coli
LOX-1 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01168
Species: Mouse
Expression System: HEK293 Cells
Ubiquitin Activating Enzyme E1/UBA1 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-02840
Species: Human
Expression System: Baculovirus Insect Cells
OGDC-E1 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-00850
Species: Human
Expression System: E. coli
Influenza A H10N8 (A/duck/Guangdong/E1/2012) Hemagglutinin/HA1 Protein (His)
Cat.No: TMPY-00015
Species: H10N8
Expression System: HEK293 Cells
ALDH1A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01583
Species: Human
Expression System: E. coli
Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E1 (His)
Cat.No: TMPH-01829
Species: HPV 11
Expression System: E. coli
YY1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00914
Species: Human
Expression System: E. coli
UBA5 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01324
Species: Human
Expression System: E. coli
Influenza A H10N8 (A/duck/Guangdong/E1/2012) Neuraminidase/NA Protein (His)
Cat.No: TMPY-00019
Species: H10N8
Expression System: Baculovirus Insect Cells
IRE1 Protein, Human, Recombinant (aa 465-977, His & GST)
Cat.No: TMPY-04413
Species: Human
Expression System: Baculovirus Insect Cells
IRE1 Protein, Human, Recombinant (aa 465-977)
Cat.No: TMPY-04753
Species: Human
Expression System: Baculovirus Insect Cells
SAE1 Protein, Human, Recombinant
Cat.No: TMPY-03441
Species: Human
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike S1 Protein (T19R & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)
Cat.No: TMPY-06417
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1+S2 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R & Q1071H, His)
Cat.No: TMPY-06271
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
PSME1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03612
Species: Human
Expression System: E. coli
Human adenovirus C serotype 5 E1B 55 kDa protein (His & Myc)
Cat.No: TMPH-00899
Species: HAdV-5
Expression System: E. coli
SARS-CoV-2 Spike S1 Protein (T19R & G142D & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)
Cat.No: TMPY-06252
Species: SARS-CoV-2
Expression System: HEK293 Cells
StxA2 Protein, Enterobacteria phage 933W, Recombinant (E189K, His & Myc)
Cat.No: TMPH-00516
Species: Enterobacteria phage 933W
Expression System: E. coli
Influenza A H3N2 Neuraminidase/NA Protein (E119V)
Cat.No: TMPY-02337
Species: H3N2
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1+S2 Protein (E154K & L452R & E484Q & D614G & P681R & E1072K & K1073R, His)
Cat.No: TMPY-06224
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
FBPase1 Protein, Human, Recombinant (His, E. coli)
Cat.No: TMPJ-00815
Species: Human
Expression System: E. coli
BACE1 Protein, Human, Recombinant
Cat.No: TMPY-00652
Species: Human
Expression System: HEK293 Cells
3CLpro/3C-like Protease Protein (E166V), SARS-COV-2, Recombinant
Cat.No: TMPK-01335
Species: SARS-CoV-2
Expression System: E. coli
NME1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04467
Species: Human
Expression System: E. coli
LYVE1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02983
Species: Mouse
Expression System: HEK293 Cells
CPNE1 Protein, Human, Recombinant (SUMO)
Cat.No: TMPY-03265
Species: Human
Expression System: Baculovirus Insect Cells
CDK1 & CCNE1 Heterodimer Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04450
Species: Human
Expression System: Baculovirus Insect Cells
SULT1E1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01660
Species: Human
Expression System: E. coli
CPNE1 Protein, Human, Recombinant
Cat.No: TMPY-03449
Species: Human
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His)
Cat.No: TMPY-06443
Species: SARS-CoV-2
Expression System: HEK293 Cells
SAE1 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-03062
Species: Human
Expression System: Baculovirus Insect Cells
3CLpro/3C-like Protease Protein (E166A), SARS-COV-2, Recombinant
Cat.No: TMPK-01347
Species: SARS-CoV-2
Expression System: E. coli
CYP2E1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02618
Species: Mouse
Expression System: E. coli
STE11 Protein, S. cerevisiae, Recombinant
Cat.No: TMPH-03458
Species: Saccharomyces cerevisiae
Expression System: E. coli
HOXB4 Protein, Human,Recombinant (L175D, E176K, E178K, His)
Cat.No: TMPJ-00879
Species: Human
Expression System: E. coli
DNASE1L3 Protein, Human, Recombinant (His)
Cat.No: TMPH-01213
Species: Human
Expression System: Baculovirus Insect Cells
Human adenovirus C serotype 5 Early E1A protein (His & SUMO)
Cat.No: TMPH-00900
Species: HAdV-5
Expression System: E. coli
SARS-CoV-2 Spike S1+S2 Protein (D614G & E154K & E484Q & G142D & H1101D & L452R & P681R & Q1071H, His)
Cat.No: TMPY-06292
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
DNASE1L3 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01212
Species: Human
Expression System: E. coli
DNASE1L3 Protein, Human, Recombinant
Cat.No: TMPH-01214
Species: Human
Expression System: E. coli
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