194
19
2
1
106
Cat. No. | Product Name | ||
---|---|---|---|
L8600 | 泛素化化合物库 | 210 compounds | |
210 种泛素化相关的小分子,用于高通量和高内涵筛选; | |||
L8500 | HIF-1化合物库 | 1336 compounds | |
1336 个HIF-1相关小分子的独特集合,可用于缺血性疾病、癌症等相关领域的药物开发和药理研究; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
CL0137 |
E1/E2/E3 Enzyme inhibitor kit
E1/E2/E3 Enzyme inhibitor kit |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T39017 |
OVA-E1 peptide
OVA-E1 peptide |
||
OVA-E1 peptide, a variant antagonist of SIINFEKL [OVA (257-264)], elicits comparable activation of the p38 and JNK cascades in both mutant and wild-type thymocytes. | |||
T36770 |
11-deoxy Prostaglandin E1
11-deoxy Prostaglandin E1 |
||
11-deoxy Prostaglandin E1 是前列腺素 E1类似物,具有支气管扩张活性,可抑制组胺诱导的支气管收缩,引起离体豚鼠的气管条松弛。 | |||
T38665 |
OVA-E1 peptide TFA
OVA-E1 peptide TFA |
p38 MAPK; JNK | MAPK |
OVA-E1 peptide TFA 在突变型和野生型胸腺细胞中都能同样地激活 p38 和 JNK 级联。 | |||
T36214 |
16,16-dimethyl Prostaglandin E1
16,16-dimethyl Prostaglandin E1 |
||
16,16-dimethyl Prostaglandin E1 是 PGE1 (T1626) 类似物,可诱导支气管收缩和血管平滑肌收缩,并抑制吲哚美辛诱导的细胞伸长。 | |||
T36726 |
6-keto Prostaglandin E1
6-keto Prostaglandin E1 |
||
6-keto Prostaglandin E1 是 PGE1 的生物活性衍生物,在抗血小板聚集和解聚作用方面发挥作用。 | |||
T36159 |
8-iso Prostaglandin E1
8-iso Prostaglandin E1 |
||
8-iso Prostaglandin E1 能引起犬肺静脉中的痉挛,还能够起到血管舒张作用。 | |||
T36775 |
13,14-dihydro Prostaglandin E1
13,14-dihydro Prostaglandin E1 |
||
13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively. 13,14-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 which has an IC50 value of 40 nM. Also, 13,14-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hyb... | |||
T36219 |
1a,1b-dihomo Prostaglandin E1
1a,1b-dihomo Prostaglandin E1 |
||
1a,1b-dihomo Prostaglandin E1 是一类前列腺素化合物。 | |||
T37778 |
19(R)-hydroxy Prostaglandin E1
19(R)-hydroxy Prostaglandin E1 |
||
19(R)-hydroxy Prostaglandin E1 是 EP1 和 EP3 受体亚型的激动剂,并对平滑肌表现出收缩活性,也是灵长类动物精液中的主要前列腺素。 | |||
T36147 |
13,14-dihydro-15-keto Prostaglandin E1
13,14-dihydro-15-keto Prostaglandin E1 |
||
13,14-dihydro-15-keto Prostaglandin E1 可抑制 ADP 诱导的人离体富血小板血浆中的血小板聚集(IC50=14.8 μg/mL),也是 PGE1 代谢物。 | |||
T125156 | Schidigerasaponin E1 | ||
Schidigerasaponin E1 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125156,CAS号为 266998-23-6。 | |||
T25269 |
Colistin A
Polymixin E1,Polymyxin E1,Colistin IV |
||
Colistin A is an antibiotic generated by certain strains of the bacteria Paenibacillus polymyxa. Colistin is a mixture of the cyclic polypeptides colistin A and B and belongs to the class of polypeptide antibiotics known as polymyxins. Colistin is effecti | |||
T24136 |
Heclin
|
E1/E2/E3 Enzyme | Ubiquitination |
Heclin 是一种 HECT E3 泛素连接酶抑制剂,通过抑制 Smurf2、Nedd4 和 WWP1 起作用,IC50 值分别为 6.8、6.3 和 6.9 μM。 | |||
T29907 |
Alprostadil sodium
PGE1 sodium salt,Prostaglandin E1 sodium |
||
Alprostadil sodium 是一种前列腺素受体配体,对小鼠 EP1、EP2、EP3、EP4和 IP 的 Ki 值分别为 36、10、1.1、2.1 和 33 nM。它诱导血管舒张并抑制血小板聚集,可作为血管扩张剂用于外周血管疾病的研究。 | |||
T29908 |
Alprostadil ethyl ester
Prostaglandin E1 ethyl ester,PGE1 ethyl ester |
||
Alprostadil ethyl ester is a biochemical used in the treatment of scleroderma. | |||
T25362 |
Ecraprost
AS013,Circulase,AS 013,AS-013,Lipo-pro-prostaglandin E1 |
||
Ecraprost is used as a prodrug of prostaglandin E1. | |||
T16901 |
SMIP004
|
Apoptosis; Others; E1/E2/E3 Enzyme | Apoptosis; Others; Ubiquitination |
SMIP004 是一种 SKP2 E3 连接酶抑制剂。 SMIP004 是人前列腺癌细胞的癌细胞特异性凋亡诱导剂。 | |||
T12261 |
NSC232003
|
E1/E2/E3 Enzyme | Ubiquitination |
NSC232003 是高效的UHRF1抑制剂,能够抑制 DNA 甲基化,并破坏 DNMT1/UHRF1 相互作用。 | |||
T16102 |
ML-792
|
E1/E2/E3 Enzyme | Ubiquitination |
ML-792 是特异性的小泛素样修饰物活化酶抑制剂。ML-792选择性抑制SAE/SUMO1和SAE/SUMO2,IC50分别为 3 和 11 nM,对 NAE/NEDD8 和 UAE/ubiquitin 抑制作用微弱,IC50分别为 32 μM 和 >100 μM。 | |||
T2158 |
Nutlin-3
Nutlin3 |
E1/E2/E3 Enzyme | Ubiquitination |
Nutlin-3 是一种 MDM2 拮抗剂,抑制 MDM2-p53 相互作用 ,Ki 为 90 nM,并激活 p53。 | |||
T16888 |
SJ-172550
|
Mdm2; E1/E2/E3 Enzyme | Apoptosis; Ubiquitination |
SJ-172550 是 MDMX 的小分子抑制剂,EC50为5 μM。 | |||
T8428 |
Subasumstat
TAK-981 |
E1/E2/E3 Enzyme | Ubiquitination |
Subasumstat (TAK-981) 是SUMOylation 酶联反应的选择性抑制剂,具有潜在的免疫激活和抗肿瘤特性。 | |||
T5374 |
NAcM-OPT
|
E1/E2/E3 Enzyme; NEDD8 | Metabolism; Ubiquitination |
NAcM-OPT 是口服活性、有效的 cullin neddylation 1 抑制剂,可以抑制 DCN1-UBE2M 相互作用。 | |||
T16699 |
PYZD-4409
|
Others; E1/E2/E3 Enzyme | Others; Ubiquitination |
PYZD-4409 是一种特异性 UBA1 抑制剂,IC50 为 20 μM。 PYZD-4409 在恶性细胞中诱导细胞死亡,并且对恶性细胞的细胞毒性优于对正常造血细胞的细胞毒性。 | |||
T5199 |
COH000
|
E1/E2/E3 Enzyme | Ubiquitination |
COH000 是不可逆的泛素样激活酶1 共价变构抑制剂,体外测得对 SUMO 化修饰的IC50=0.2 μM。 | |||
T13244 |
Ubiquitination-IN-1
|
Others | Others |
Ubiquitination-IN-1 是一种有效的泛素化和Cksl-Skp2蛋白互作抑制剂 (IC50=0.17 μM) 抑制剂,增加 p27 水平,可通过阻断肿瘤抑制因子的降解发挥作用。 | |||
T7379 |
2-D08
|
E1/E2/E3 Enzyme; TAM Receptor | Tyrosine Kinase/Adaptors; Ubiquitination |
2-D08是小泛素样修饰蛋白抑制剂。2-D08也能抑制 Axl,IC50=0.49 nM。 | |||
T3517 |
RO8994
|
Mdm2; E1/E2/E3 Enzyme; p53 | Apoptosis; Ubiquitination |
RO8994是一种高效且特异性的螺吲哚酮小分子 MDM2 抑制剂,MTT 增殖试验和HTRF 结合试验的IC50 为 20 nM 和 5 nM。 | |||
T7415 |
DKM 2-93
|
E1/E2/E3 Enzyme | Ubiquitination |
DKM 2-93是相对选择性 UBA5抑制剂,IC50=430 μM。 | |||
T7889 |
C25-140
|
Others; TNF; E1/E2/E3 Enzyme; NF-κB | Apoptosis; NF-κB; Others; Ubiquitination |
C25-140 是一种具有口服活性和一定选择性的 TRAF6-Ubc13相互作用抑制剂。它直接与 TRAF6 结合,阻断 TRAF6 和 Ubc13 的相互作用,降低 TRAF6 和 NF-κB 的活性,并与自身免疫对抗。 | |||
T9236 |
WSB1 Degrader 1
|
Others; E1/E2/E3 Enzyme | Others; Ubiquitination |
WSB1 Degrader 1 是具有口服活性的 WSB1降解剂,具有抗癌活性。 | |||
T6629 |
PYR-41
PYR41,PYR 41 |
Apoptosis; E1/E2/E3 Enzyme | Apoptosis; Ubiquitination |
PYR-41 是一种选择性,可透过细胞的泛素活化酶 E1抑制剂,IC50值小于10 μM。 | |||
T23371 |
SMER3
SMER 3 |
Others; Ligand for E3 Ligase | Others; PROTAC |
SMER3 是选择性的 Skp1-Cullin-F-box (SCF)Met30泛素连接酶抑制剂。SMER 3 通过抑制 SCFMet30来增强 Rapamycin 的生长抑制作用。 | |||
T3653 |
MX69
|
Mdm2; E1/E2/E3 Enzyme; IAP | Apoptosis; Ubiquitination |
MX69 是用于抗癌研究的一种MDM2/XIAP 抑制剂。 | |||
T6149 |
YH239-EE
|
Apoptosis; E1/E2/E3 Enzyme | Apoptosis; Ubiquitination |
YH239-EE 是 YH239 的乙酯,是 p53-MDM2 拮抗剂和凋亡诱导剂。 | |||
T10703 |
Mezigdomide
CC-92480 |
Apoptosis; E1/E2/E3 Enzyme; Molecular Glues | Apoptosis; PROTAC; Ubiquitination |
Mezigdomide (CC-92480) 是一种有效的、新型的、具有选择性的和具有活性的 cereblon E3 泛素连接酶调节剂 (CELMoD),常以分子胶的方式发挥作用。Mezigdomide 具有抗骨髓瘤活性。 | |||
T13349 |
WS-383
|
E1/E2/E3 Enzyme | Ubiquitination |
WS-383 是高效、选择性、可逆的DCN1-UBC12相互作用抑制剂,IC50为11 nM。它抑制 Cul3/1 的类泛素化修饰,引起 NRF2,p21和p27 的积累。 | |||
T11980 |
MD-224
|
Mdm2; E1/E2/E3 Enzyme; PROTACs | Apoptosis; PROTAC; Ubiquitination |
MD-224是一种基于蛋白水解靶向嵌合体(PROTAC)概念的高效、高效的MDM2降解剂,是一类新型抗癌剂。 | |||
T3317 |
SZL P1-41
|
Apoptosis; Others; E1/E2/E3 Enzyme | Apoptosis; Others; Ubiquitination |
SZL P1-41 是 Skp2 抑制剂,可以阻止 Skp2-Skp1 复合物的组装。 它选择性地抑制 Skp2 SCF E3 连接酶活性,还在体内外抑制 Skp2 介导的 p27 和 Akt 泛素化。 它通过触发细胞衰老和抑制糖酵解来抑制 Y 细胞和 Y 干细胞的存活,有抗肿瘤作用。 | |||
T8564 |
BC-1382
|
Others; E1/E2/E3 Enzyme | Others; Ubiquitination |
BC-1382 是E3泛素连接酶HECTD2抑制剂,能够特异性破坏 HECTD2/PIAS1 相互作用 (IC50≈ 5 nM)。BC-1382具有抗炎活性。 | |||
T3110 |
PRT4165
NSC600157,PRT 4165 |
BMI-1; Others; E1/E2/E3 Enzyme | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others; Ubiquitination |
PRT4165 (NSC600157) 是有效的 PRC1介导 H2A 泛素化的抑制剂。 | |||
T4253 |
Skp2 Inhibitor C1
SKPin C1 |
Others; E1/E2/E3 Enzyme | Others; Ubiquitination |
Skp2 Inhibitor C1 (SKPin C1)(SKPin C1)是Skp2介导p27降解的特异性抑制剂。 | |||
T6254 |
Idasanutlin
RG7388,Ro 5503781,依达奴林 |
Mdm2; E1/E2/E3 Enzyme | Apoptosis; Ubiquitination |
Idasanutlin (Ro 5503781) 是一种有效且特异性的 p53-MDM2 抑制剂 ,IC50值为 6 nM。 | |||
T5555 |
Siremadlin
NVP-HDM 201 |
E1/E2/E3 Enzyme | Ubiquitination |
Siremadlin (NVP-HDM 201) 是一种有效的、可口服的、高度特异性的 p53-MDM2 相互作用抑制剂。 | |||
T3549 |
Avadomide
CC 122 |
Apoptosis; E1/E2/E3 Enzyme; Ligand for E3 Ligase | Apoptosis; PROTAC; Ubiquitination |
Avadomide (CC 122) 是口服有效的cereblon 调节剂,可以调节 cereblon E3 连接酶活性,诱导弥漫性大 B 细胞淋巴瘤细胞凋亡,具有抗肿瘤和免疫调节活性。 | |||
T16974 |
TAK-243
MLN7243 |
Apoptosis; E1/E2/E3 Enzyme; NF-κB | Apoptosis; NF-κB; Ubiquitination |
TAK-243 (MLN7243) 是一种泛素激活酶 UAE 的抑制剂 (IC50=1 nM),具有选择性。TAK-243 可阻断泛素结合,破坏单泛素信号传导以及整体蛋白质泛素化。TAK-243 具有抗肿瘤活性,可以促进细胞凋亡。 | |||
TQ0127 |
Navtemadlin
AMG232,CS-1300 |
Mdm2; E1/E2/E3 Enzyme | Apoptosis; Ubiquitination |
Navtemadlin (AMG232) 是一种有效的、选择性的、可口服的 p53-MDM2 相互作用抑制剂,IC50值为 0.6 nM。它以 0.045 nM 的 Kd 与 MDM2 结合。 | |||
T6965 |
RG7112
RG-7112,RG 7112,RO5045337 |
Mdm2; E1/E2/E3 Enzyme | Apoptosis; Ubiquitination |
RG7112 (RO5045337) 是一种口服生物可利用的选择性 p53-MDM2 抑制剂。 | |||
T2243 |
Serdemetan
JNJ-26854165,N-[2-(1H-吲哚-3-基)乙基]-N'-(4-吡啶基)-1,4-苯二胺 |
Apoptosis; Mdm2; E1/E2/E3 Enzyme; p53 | Apoptosis; Ubiquitination |
Serdemetan (JNJ-26854165) 是一种 HDM2泛素连接酶拮抗剂,能诱导 p53野生型细胞的早期凋亡。 | |||
TQ0231 |
NVP-CGM097
CGM097 |
Mdm2; E1/E2/E3 Enzyme | Apoptosis; Ubiquitination |
NVP-CGM097 (CGM097) 是一种选择性MDM2抑制剂,对hMDM2的IC50为 1.7 nM。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12090 |
Mogroside I E1
罗汉果苷 I E1 |
Others | Others |
Mogroside I E1 是三萜糖苷,是非糖类甜味剂。其中 Mogroside 的甜度比蔗糖高,具有抗氧化,抗糖尿病和抗癌特性。 | |||
T1626 |
Prostaglandin E1
前列地尔,PGE1,列腺素E1,Alprostadil |
Endogenous Metabolite; Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation; Metabolism |
Prostaglandin E1 (Alprostadil) 是一种前列腺素受体配体,对小鼠 EP1、EP2、EP3、EP4和 IP 的 Ki 值分别为 36、10、1.1、2.1 和 33 nM。它诱导血管舒张并抑制血小板聚集,可作为血管扩张剂用于外周血管疾病的研究。 | |||
T16733 |
Resolvin E1
RvE1 |
Others | Others |
Resolvin E1 is an effective endogenous pro-resolving mediator of inflammation. Resolvin E1 has unique counterregulatory actions that inhibit PMN transendothelial migration. Resolvin E1 also acts as an effective inhibitor of leukocyte infiltration, dendrit | |||
T80996 |
Theasaponin E1
|
||
Theasaponin E1,一种可从茶籽分离的茶皂苷,对人肿瘤细胞系K562和HL60展示了抗肿瘤潜能。此外,Theasaponin E1具备醌还原酶(QR)诱导活性,有助于作为抗癌预防药物的研究。 | |||
T83902 |
Polymyxin E1 sulfate
Colistin A sulfate |
||
Polymyxin E1,是一种肽类抗生素,也是原初从B. polymyxa分离得到的阳离子脂肽抗生素colistin的主要成分。对P. aeruginosa和E. coli具有活性(MICs分别为2和0.8 µg/ml)。 | |||
T4S0181 |
Hinokiflavone
日本扁柏黄酮,扁柏双黄酮 |
MMP; BCL; E1/E2/E3 Enzyme | Apoptosis; Proteases/Proteasome; Ubiquitination |
Hinokiflavone 是pre-mRNA 剪接活性的新型调节剂,通过抑制剪接体装配来阻止pre-mRNA 底物的剪接,特别是阻止 B complex 的形成。它是SUMO protease 蛋白酶抑制剂,能够抑制前哨蛋白特异性蛋白酶 1 的活性。 | |||
TN1124 |
Neoeriocitrin
|
AChE | Neuroscience |
Neoeriocitrin 是一种有效的乙酰胆碱酯酶抑制剂,分离于自百日草,在 MC3T3-E1 中显示出对增殖和成骨分化的活性。 | |||
T9352 |
hydrocotarnine
|
Others | Others |
hydrocotarnine 是 Cbl 的抑制剂。 | |||
T4036 |
Solasodine
Solancarpidine,Purapuridine,澳洲茄铵,Solasodin |
Apoptosis; Others; E1/E2/E3 Enzyme; Antifungal | Apoptosis; Microbiology/Virology; Others; Ubiquitination |
Solasodine (Purapuridine) 是存在于茄科植物中的一种类固醇生物碱。它具有神经保护、降压、抗真菌、抗癌、抗动脉粥样硬化、抗雄激素和抗炎活性。 | |||
T2947 |
Indole-3-carbinol
吲哚-3-甲醇,I3C,3-Indolemethanol,3-吲哚甲醇,Indole-3-Methanol |
E1/E2/E3 Enzyme; NF-κB; Aryl Hydrocarbon Receptor; Endogenous Metabolite; p53 | Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; Ubiquitination |
Indole-3-carbinol (I3C) 是樟子松中的一种天然产物,是可口服的硫代葡萄糖苷葡糖苷酶裂解产物。它是芳烃受体 (AhR) 的激动剂,可抑制 NF-κB 和 IκBα 激酶活化。 | |||
T6S2123 |
Ginkgolic Acid
Romanicardic acid,Ginkgolic acid I,Ginkgolic acid (15:1),银杏酸C15:1,银杏酸,Ginkgolic acid C15:1 |
Others; E1/E2/E3 Enzyme | Others; Ubiquitination |
Ginkgolic Acid (Romanicardic acid) 是一种天然化合物, 在体外实验中抑制SUMOylation,IC50=3.0 μM。 | |||
T21518 |
Colistin methanesulfonate sodium salt
粘杆菌素甲基磺酸钠,Colistin Methanesulfonate (sodium salt) |
Cell wall; Antibacterial | Immunology/Inflammation; Microbiology/Virology |
Colistin methanesulfonate sodium salt (Colistimethate Sodium) 是一种来自 Bacillus colistinus 的环状多肽抗生素,由多粘菌素 E1 和 E2 组成。 | |||
T1245 |
Colistin sulfate
Colistin sulfate (1066-17-7 free base),Polymixin E Sulfate,Polymyxin E Sulfate,硫酸粘杆菌素 |
Cell wall; Antibacterial; Antibiotic; Autophagy | Autophagy; Immunology/Inflammation; Microbiology/Virology |
Colistin sulfate (Colistin sulfate (1066-17-7 free base)) 是抑制革兰氏阴性细菌的一种多肽抗生素,与革兰氏阴性细菌的外细胞膜中的脂多糖和磷脂结合起作用。 | |||
T5S2129 |
Sciadopitysin
|
TNF; NF-κB | Apoptosis; NF-κB |
Sciadopitysin 是一种双黄酮类化合物,来自银杏叶片中。它通过抑制NF-κB 活化并降低c-Fos 和NFATc1的表达来抑制 RANKL 诱导的破骨细胞生成和骨丢失。 | |||
TN6926 |
Paeonoside
|
Others | Others |
Paeonoside 发现与P. suffruticosa 中,具有生物活性,可以促进成骨细胞分化过程中的伤口愈合和迁移。Paeonoside 具有一定的抗糖尿病活性,可防止脓毒症和败血症引起的死亡。Paeonoside 对 MC3T3-E1细胞的前成骨细胞没有细胞毒性作用,以剂量依赖性的方式显著恢复伤口区域并促进细胞迁移和促进碱性磷酸酶(ALP)染色及其活性。 | |||
T4S1943 |
Kirenol
奇壬醇,奇任醇,Kirel |
Wnt/beta-catenin | Cytoskeletal Signaling; Stem Cells |
Kirenol (Kirel) 是分离自 Siegesbeckia orientalis 中的,具有抗氧化、抗炎、抗过敏、抗关节炎活性,可用于缓解疼痛的研究。 | |||
T6S1559 |
Aurantio-obtusin
|
Others | Others |
Aurantio-obtusin 是从决明子中分离出的蒽醌类化合物,具有抗炎、抗凝血、抗氧化、抗高血压的活性。它能抑制 IgE 介导的肥大细胞和过敏模型中的过敏反应,具有研究过敏相关疾病的潜力。在大鼠中,它通过内皮细胞 PI3K/AKT/ eNOS 依赖信号通路放松全身动脉,是潜在的新型血管扩张剂。 | |||
TQ0262 |
Dihomo-γ-linolenic acid
Diroleuton,顺式-8,11,14-二十烷三烯酸甲酯,all-cis-8,11,14-Eicosatrienoic acid,Ro 12-1989 |
Others | Others |
Ro 12-1989 can be converted into prostaglandin E1 (PGE1). Ro 12-1989 competes with arachidonic acid for COX and lipoxygenase, inhibiting the production of arachidonic acid's eicosanoids. | |||
TN3753 |
Dalbergioidin
|
Tyrosinase; ROS; Akt; PI3K; TGF-beta/Smad | Cytoskeletal Signaling; Immunology/Inflammation; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells |
Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces bikiniensis that has commonly been used as an indicator organism. Dalbergioidin protects MC3T3-E1 osteoblastic cells against H2O2-induced cell damage through activation of the PI3K/AKT/SMAD1 pathway, suggests that it may be useful in bone metabolism diseases, particularly osteoporosis. Dalbergioidin also ameliorates doxorubicin-induced ... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04135 |
Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His)
HCV-E1 |
HCV | HEK293 Cells |
Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.7 kDa and the accession number is AAC15725.1. | |||
TMPJ-00625 |
Serpin E1 Protein, Mouse, Recombinant (His)
Pai1,Planh1,Plasminogen activator inhibitor 1,Serpin E1<... |
Mouse | HEK293 Cells |
Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis. | |||
TMPH-00597 |
Colicin-E1 Protein, E. coli, Recombinant (His & Myc)
cea,Colicin-E1 |
E. coli | E. coli |
This colicin is a channel-forming colicin. This class of transmembrane toxins depolarize the cytoplasmic membrane, leading to dissipation of cellular energy.; Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria. | |||
TMPH-00596 |
Colicin-E1 Protein, E. coli, Recombinant (Cell-Free, His & Myc)
Colicin-E1,cea |
E. coli | E. coli |
This colicin is a channel-forming colicin. This class of transmembrane toxins depolarize the cytoplasmic membrane, leading to dissipation of cellular energy.; Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria. | |||
TMPY-02777 |
Cyclin E Protein, Human, Recombinant (His & GST)
cyclin E1,CCNE |
Human | Baculovirus Insect Cells |
Cyclin E Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75 kDa and the accession number is P24864-1. | |||
TMPY-01550 |
Cyclin E Protein, Human, Recombinant (His)
cyclin E1,CCNE |
Human | Baculovirus Insect Cells |
Cyclin E Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49.3 kDa and the accession number is P24864-1. | |||
TMPY-03535 |
Cyclin E Protein, Mouse, Recombinant (His & GST)
cyclin E1,AW538188,CycE1 |
Mouse | Baculovirus Insect Cells |
Cyclin E Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 74.8 kDa and the accession number is AAH62152.1. | |||
TMPY-01693 |
Butyrylcholinesterase Protein, Human, Recombinant (His)
CHE1,E1,butyrylcholinesterase,CHE2 |
Human | HEK293 Cells |
Butyrylcholinesterase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.5 kDa and the accession number is P06276. | |||
TMPY-06748 |
UBA6 Protein, Human, Recombinant (GST)
ubiquitin-like modifier activating enzyme 6,UBE1L2,... |
Human | Baculovirus Insect Cells |
UBA6 (Ubiquitin Like Modifier Activating Enzyme 6) is a Protein Coding gene. The UBA6 gene, located on 4q13.2, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. Uba6 is a homolog of the ubiquitin-activating enzyme, Uba1, and activates two ubiquitin-like proteins (UBLs), ubiquitin and FAT10. UBA6 is an alternative enzyme for ubiquitin activation in vertebrates that plays a pivotal role in early mouse development. UBA6 is widely expressed in the lymph n... | |||
TMPY-01595 |
PCBP1 Protein, Human, Recombinant (His)
HNRPE1,hnRNP-E1,HEL-S-85,HNRPX,poly(rC) bi... |
Human | E. coli |
Poly(rC)-binding protein 1, also known as Heterogeneous nuclear ribonucleoprotein E1, Alpha-CP1, Nucleic acid-binding protein SUB2.3 and PCBP1, is a family member of heterogeneous nuclear ribonucleoproteins (hnRNPs) that belong to RNA-binding proteins and bear three KH domains. PCBP1 is loosely bound in the nucleus. It may shuttle between the nucleus and the cytoplasm. It is abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in pr... | |||
TMPK-01168 |
LOX-1 Protein, Mouse, Recombinant (His)
LOXIN,LOX-1,CLEC8A,Ox-LDL receptor 1,SLOX1,LOX1,SCARE1 |
Mouse | HEK293 Cells |
LOX-1 is a transmembrane glycoprotein that binds to and internalizes ox-LDL.LOX-1 gene deletion in mice and anti-LOX-1 therapy has been shown to decrease inflammation, oxidative stress and atherosclerosis. LOX-1 deletion also results in damage from ischemia, making LOX-1 a promising target of therapy for atherosclerosis and related disorders. In this article we focus on the different mechanisms for regulation, signaling and the various effects of LOX-1 in contributing to atherosclerosis. | |||
TMPY-02840 |
Ubiquitin Activating Enzyme E1/UBA1 Protein, Human, Recombinant (His & GST)
UBE1,ubiquitin-like modifier activating enzyme 1,UB... |
Human | Baculovirus Insect Cells |
UBE1, also known as UBA1, belongs to the ubiquitin-activating E1 family. UBE1 gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. UBE1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. It also catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation by first adenylating its C-terminal glycine residue w... | |||
TMPH-00850 |
OGDC-E1 Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
OGDC-E1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 59.1 kDa and the accession number is Q02218. | |||
TMPY-00015 |
Influenza A H10N8 (A/duck/Guangdong/E1/2012) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H10N8 | HEK293 Cells |
Influenza A H10N8 (A/duck/Guangdong/E1/2012) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37 kDa and the accession number is I6PXD4. | |||
TMPY-01583 |
ALDH1A1 Protein, Human, Recombinant (His)
ALDH11,ALDC,PUMB1,ALDH-E1,HEL-S-53e,HEL-9,aldehyde ... |
Human | E. coli |
Aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), also known as Aldehyde dehydrogenase 1 (ALDH1), or Retinaldehyde Dehydrogenase 1 (RALDH1), is an enzyme that is expressed at high levels in stem cells and that has been suggested to regulate stem cell function. The retinaldehyde dehydrogenase (RALDH) subfamily of ALDHs, composed of ALDH1A1, ALDH1A2, ALDH1A3, and ALDH8A1, regulate development by catalyzing retinoic acid biosynthesis. The ALDH1A1 protein belongs to the aldehyde dehydrogenases f... | |||
TMPH-01829 |
Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E1 (His)
|
HPV 11 | E. coli |
Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E1 (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.1 kDa and the accession number is P04014. | |||
TMPJ-00914 |
YY1 Protein, Human, Recombinant (His)
NF-E1,Transcriptional repressor protein YY1,Yin and... |
Human | E. coli |
Transcriptional repressor protein YY1(YY1)contains 4 C2H2-type zinc fingers and belongs to the YY transcription factor family. Multifunctional transcription factor exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. The effect on transcription regulation of the protein is depending upon the context in which it binds and diverse mechanisms of action include direct activation or repression, indirect acti... | |||
TMPJ-01324 |
UBA5 Protein, Human, Recombinant (His)
Ubiquitin-like modifier-activating enzyme 5,UBE1DC1... |
Human | E. coli |
UBA5 is a member of the ubiquitin-activating E1 family and UBA5 subfamily. Ubiquitin and ubiquitin-like proteins are recognized as covalently conjugated to various cellular substrates by a three-step enzymatic pathway. The ubiquitin-activating enzyme (E1) has a vital role in the first step of ubiquitination pathway to activate ubiquitin or ubiquitin-like proteins. UBA5 activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy th... | |||
TMPY-00019 |
Influenza A H10N8 (A/duck/Guangdong/E1/2012) Neuraminidase/NA Protein (His)
NA Protein,Neuraminidase |
H10N8 | Baculovirus Insect Cells |
Influenza A H10N8 (A/duck/Guangdong/E1/2012) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.2 kDa and the accession number is I6PU08. | |||
TMPY-04413 |
IRE1 Protein, Human, Recombinant (aa 465-977, His & GST)
hIRE1p,endoplasmic reticulum to nucleus signaling 1... |
Human | Baculovirus Insect Cells |
IRE1 Protein, Human, Recombinant (aa 465-977, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 86 kDa and the accession number is O75460-1. | |||
TMPY-04753 |
IRE1 Protein, Human, Recombinant (aa 465-977)
hIRE1p,endoplasmic reticulum to nucleus signaling 1... |
Human | Baculovirus Insect Cells |
IRE1 Protein, Human, Recombinant (aa 465-977) is expressed in Baculovirus insect cells. The predicted molecular weight is 58.3 kDa and the accession number is O75460-1. | |||
TMPY-03441 |
SAE1 Protein, Human, Recombinant
SUA1,SUMO1 activating enzyme subunit 1,HSPC140,UBLE1 |
Human | Baculovirus Insect Cells |
SAE1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 38.6 kDa and the accession number is Q9UBE0. | |||
TMPY-06417 |
SARS-CoV-2 Spike S1 Protein (T19R & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (T19R & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.22 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-06271 |
SARS-CoV-2 Spike S1+S2 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R & Q1071H, His)
|
SARS-CoV-2 | Baculovirus Insect Cells |
SARS-CoV-2 Spike S1+S2 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R & Q1071H, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.51 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-03612 |
PSME1 Protein, Human, Recombinant (His)
proteasome (prosome, macropain) activator subunit 1 (PA28 al... |
Human | E. coli |
PA28A, also known as PSME1, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 1 non-ATPase subunit... | |||
TMPH-00899 |
Human adenovirus C serotype 5 E1B 55 kDa protein (His & Myc)
|
HAdV-5 | E. coli |
Human adenovirus C serotype 5 E1B 55 kDa protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 62.4 kDa and the accession number is P03243. | |||
TMPY-06252 |
SARS-CoV-2 Spike S1 Protein (T19R & G142D & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (T19R & G142D & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.27 kDa and the accession number is A0A6G7K2L4. | |||
TMPH-00516 |
StxA2 Protein, Enterobacteria phage 933W, Recombinant (E189K, His & Myc)
|
Enterobacteria phage 933W | E. coli |
The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits. | |||
TMPY-02337 |
Influenza A H3N2 Neuraminidase/NA Protein (E119V)
NA Protein |
H3N2 | HEK293 Cells |
Influenza A H3N2 Neuraminidase/NA Protein (E119V) is expressed in HEK293 mammalian cells. The accession number is C0LU95. | |||
TMPY-06224 |
SARS-CoV-2 Spike S1+S2 Protein (E154K & L452R & E484Q & D614G & P681R & E1072K & K1073R, His)
|
SARS-CoV-2 | Baculovirus Insect Cells |
SARS-CoV-2 Spike S1+S2 Protein (E154K & L452R & E484Q & D614G & P681R & E1072K & K1073R, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.5 kDa and the accession number is A0A6G7K2L4. | |||
TMPJ-00815 |
FBPase1 Protein, Human, Recombinant (His, E. coli)
6-Bisphosphate 1-Phosphohydrolase 1,FBP1,FBP,FBPase 1,D-Fruc... |
Human | E. coli |
Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young chi... | |||
TMPY-00652 |
BACE1 Protein, Human, Recombinant
BACE,HSPC104,β-site APP-cleaving enzyme 1,beta-site APP-clea... |
Human | HEK293 Cells |
BACE1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 49 kDa and the accession number is A0A024R3D7. | |||
TMPK-01335 |
3CLpro/3C-like Protease Protein (E166V), SARS-COV-2, Recombinant
M Proteinase,Mpro,3CL Protease,3CL-Mpro |
SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (E166V), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.80 kDa and the accession number is YP_009725301.1. | |||
TMPY-04467 |
NME1 Protein, Human, Recombinant (His)
NME/NM23 nucleoside diphosphate kinase 1,NB,NDPK-A,NM23-H1,N... |
Human | E. coli |
NME1, also known as Nucleoside Diphosphate Kinase A (NDK-A), or NM23-H1, belongs to the NDK family. NM23-H1 is known to have a metastasis suppressive activity in many tumor cells. Recent studies have shown that the interacting proteins with NM23-H1 which mediate cell proliferation, may act as modulators of the metastasis suppressor activity. The interacting proteins with NM23-H1 can be classified into 3 groups. The first group of proteins can be classified as upstream kinases of NM23-H1 such as ... | |||
TMPY-02983 |
LYVE1 Protein, Mouse, Recombinant (hFc)
1200012G08Rik,Lyve-1,lymphatic vessel endothelial hyaluronan... |
Mouse | HEK293 Cells |
LYVE1, also known as LYVE-1, is a type I integral membrane glycoprotein. It contains 1 Link domain and is mainly expressed in endothelial cells lining lymphatic vessels. LYVE1 acts as a receptor and binds to both soluble and immobilized hyaluronan. It may function in lymphatic hyaluronan transport and have a role in tumor metastasis. LYVE1 also is a cell surface receptor on lymphatic endothelial cells that can be used as a lymphatic endothelial cell marker, and sort these cells for experimental ... | |||
TMPY-03265 |
CPNE1 Protein, Human, Recombinant (SUMO)
CPN1,copine I,COPN1 |
Human | Baculovirus Insect Cells |
CPNE1 Protein, Human, Recombinant (SUMO) is expressed in Baculovirus insect cells with SUMO tag. The predicted molecular weight is 72.7 kDa and the accession number is Q99829. | |||
TMPY-04450 |
CDK1 & CCNE1 Heterodimer Protein, Human, Recombinant (His & GST)
P34CDC2 & CCNE1,CDC2,CDKN1,CDK1,CCNE,CDC28A |
Human | Baculovirus Insect Cells |
CDK1 & CCNE1 Heterodimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 109.7 kDa and the accession number is NP_001777.1&NP_001229.1. | |||
TMPY-01660 |
SULT1E1 Protein, Human, Recombinant (His)
ST1E1,EST,sulfotransferase family 1E member 1,EST-1... |
Human | E. coli |
Estrogen sulfotransferase, also known as Sulfotransferase, estrogen-preferring, Sulfotransferase 1E1, SULT1E1 and ST1E1, is a cytoplasm enzyme that belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SULT1E1 may control the level of the estrogen receptor by sulfurylating free estradio... | |||
TMPY-03449 |
CPNE1 Protein, Human, Recombinant
CPN1,COPN1,copine I |
Human | Baculovirus Insect Cells |
CPNE1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 59.2 kDa and the accession number is Q99829. | |||
TMPY-06443 |
SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.29 kDa and the accession number is YP_009724390.1. | |||
TMPY-03062 |
SAE1 Protein, Human, Recombinant (His & GST)
UBLE1A,SUMO1 activating enzyme subunit 1,AOS1,HSPC1... |
Human | Baculovirus Insect Cells |
SAE1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 66.3 kDa and the accession number is Q9UBE0. | |||
TMPK-01347 |
3CLpro/3C-like Protease Protein (E166A), SARS-COV-2, Recombinant
3CL-Mpro,3CL Protease,M Proteinase,Mpro |
SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (E166A), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 34.4kDa and the accession number is YP_009725301.1. | |||
TMPH-02618 |
CYP2E1 Protein, Mouse, Recombinant (His)
Cyp2e1,Cytochrome P450 2E1,Cytochrome P450... |
Mouse | E. coli |
A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be invo... | |||
TMPH-03458 |
STE11 Protein, S. cerevisiae, Recombinant
|
Saccharomyces cerevisiae | E. coli |
Serine/threonine protein kinase required for cell-type-specific transcription and signal transduction in yeast. It is thought that it phosphorylates the STE7 protein kinase which itself, phosphorylates the FUS3 and or KSS1 kinases. STE11 Protein, S. cerevisiae, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.5 kDa and the accession number is P23561. | |||
TMPJ-00879 |
HOXB4 Protein, Human,Recombinant (L175D, E176K, E178K, His)
Homeobox protein Hox-2.6,HOX2F,HOXB4,Homeobox protein Hox-2F... |
Human | E. coli |
Homeobox B4 (HOXB4) is encoded by the HOXB4 gene which is a member of the the class I homeobox (HOX) gene family and encodes a nuclear protein with a homeobox DNA-binding domain. These genes are master control regulators of developmental programs including embryonic and adult hematopoiesis. Multiple HOX genes, including HOXB4, are highly expressed in the hematopoietic stem cells (HSC) compartment. HOXB4 gene can act in opposite ways when expressed by different cells, promoting the proliferation ... | |||
TMPH-01213 |
DNASE1L3 Protein, Human, Recombinant (His)
DNase I homolog protein DHP2,DNAS1L3,DNase I-like 3,Deoxyrib... |
Human | Baculovirus Insect Cells |
Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA. Acts in internucleosomal DNA fragmentation (INDF) during apoptosis and necrosis. The role in apoptosis includes myogenic and neuronal differentiation, and BCR-mediated clonal deletion of self-reactive B cells. Is active on chromatin in apoptotic cell-derived membrane-coated mic... | |||
TMPH-00900 |
Human adenovirus C serotype 5 Early E1A protein (His & SUMO)
|
HAdV-5 | E. coli |
Human adenovirus C serotype 5 Early E1A protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.8 kDa and the accession number is P03255. | |||
TMPY-06292 |
SARS-CoV-2 Spike S1+S2 Protein (D614G & E154K & E484Q & G142D & H1101D & L452R & P681R & Q1071H, His)
|
SARS-CoV-2 | Baculovirus Insect Cells |
SARS-CoV-2 Spike S1+S2 Protein (D614G & E154K & E484Q & G142D & H1101D & L452R & P681R & Q1071H, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.48 kDa and the accession number is A0A6G7K2L4. | |||
TMPH-01212 |
DNASE1L3 Protein, Human, Recombinant (His & Myc)
LSD,Liver and spleen DNase,Deoxyribonuclease I-like 3,DNAS1L... |
Human | E. coli |
Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA. Acts in internucleosomal DNA fragmentation (INDF) during apoptosis and necrosis. The role in apoptosis includes myogenic and neuronal differentiation, and BCR-mediated clonal deletion of self-reactive B cells. Is active on chromatin in apoptotic cell-derived membrane-coated mic... | |||
TMPH-01214 |
DNASE1L3 Protein, Human, Recombinant
DHP2,Deoxyribonuclease I-like 3,Deoxyribonuclease gamma,DNas... |
Human | E. coli |
Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA. Acts in internucleosomal DNA fragmentation (INDF) during apoptosis and necrosis. The role in apoptosis includes myogenic and neuronal differentiation, and BCR-mediated clonal deletion of self-reactive B cells. Is active on chromatin in apoptotic cell-derived membrane-coated mic... | |||
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