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Search Results for " adr "

Targets Recommended: Adrenergic Receptor Endogenous Metabolite

111

抑制剂 & 化合物

10

天然产物

1

化合物库

1

TargetMol 试剂盒

11

重组蛋白

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Cat. No.	Product Name
L2700	肾上腺素能受体化合物库		193 compounds
	193 种特异靶向肾上腺素受体的生物活性小分子化合物的集合，是相关疾病药物筛选的有效工具；

化合物库

肾上腺素能受体化合物库

Cat.No: L2700

Compounds: 193

Cat. No.	Product Name	Form	Specificity Of Inhibition
CL0051	Adrenergic Receptor antagonist/agonist kit Adrenergic Receptor antagonist/agonist kit

TargetMol 试剂盒

Adrenergic Receptor antagonist/agonist kit

Cat.No: CL0051

Cat. No.	Product Name	Target	Signaling Pathways
T29670	ADR-925 ICRF198,ICRF-198,ADR 925,ICRF 198,ADR925	Endogenous Metabolite	Metabolism
	ADR-925 (ICRF 198) 是右雷佐生的一种活性螯合铁代谢物，具有使新生大鼠心肌细胞免受阿霉素诱导的损伤的能力。
T23642	ADR-851 free base ADR851 free base
	ADR-851 free base is an antagonist of the HT3 receptor.
T23641	ADR 882 ADR882,ADR-882
	ADR 882 is an antagonist of the 5-HT3 receptor. It has analgesic properties.
T23642L	ADR-851 HCl Adr-851,Adr 851,Adr851
	ADR-851 HCl is an HT3 receptor antagonist. It works against mechanical, acute thermal, and formalin-induced inflammatory pain.
T6467	Cardioxane ADR-529 Hydrochloride,ICRF-187 hydrochloride,ADR-529,右雷佐生盐酸盐,Dexrazoxane HCl,Cardioxane hydrochloride,ICRF-187	Topoisomerase	DNA Damage/DNA Repair
	Cardioxane (ADR-529) 是一种心脏保护剂。
T22305	Dexrazoxane 右雷佐生,ICRF-187	Others	Others
	Dexrazoxane (ICRF-187) 是一种心脏保护剂。
T9244	σ1 Receptor antagonist-1	Sigma receptor	GPCR/G Protein
	σ1 Receptor antagonist-1 是高选择性的 sigma 1受体拮抗剂，pKi 为10.28。它抑制细胞生长，在 G0/G1 期阻滞细胞周期并诱导 MCF-7/ADR 细胞凋亡。
T74734	Truncated ADR58
	Truncated ADR58 通过将全长ADR58的71个碱基缩短至31个碱基而制得。该化合物维持了与全长ADR58相似的功能性，能够高效且选择性地担任人肿瘤抑制素M(OSM)的拮抗剂，阻碍OSM与gp130受体的结合，特异性地抗拒OSM介导的信号传递。Truncated ADR58在研究类风湿性关节炎等相关疾病中有应用。
T6018	Zosuquidar trihydrochloride 唑喹达三盐酸盐,Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride	P-gp	Membrane transporter/Ion channel; Neuroscience
	Zosuquidar trihydrochloride (LY-335979 trihydrochloride) 是一种P-糖蛋白抑制剂，Ki 值为 59 nM。
T3628	Madrasin DDD00107587	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Madrasin (DDD00107587) 是剪接抑制剂，在体外能够阻止剪接中间体和产物的形成，并干扰剪接体组装途径中的一个或多个早期步骤。它能在体外抑制 pre-mRNA 的剪接，并修饰细胞中内源性 pre-mRNA 的剪接。
T7197	Fadrozole	Aromatase	Endocrinology/Hormones
	Fadrozole 是一种有效的、非甾体类的、选择性的芳香化酶抑制剂(IC50:6.4 nM)。
T68599	Orphenadrine Orphenadrine (free base)	Sodium Channel; NMDAR; AChR	Membrane transporter/Ion channel; Neuroscience
	Orphenadrine 是一种非竞争性的 N-甲基-D-天冬氨酸（NMDA）受体拮抗剂，以浓度依赖性方式抑制克隆的 HERG 通道，在 HEK 细胞中产生0.85μM 的 IC。Orphenadrine 是中枢和外周毒蕈碱受体的拮抗剂，通过孔残基 Y652或 F656突变阻断衰减。 Orphenadrine 具有抗痉挛、镇痛和抗胆碱能活性，对在体外和体内对谷氨酸神经毒性具有保护作用。Orphenadrine 对钠离子通道具有抑制作用，可用来治疗帕金森。
T70047	Bedoradrine Bedoradrine free base	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Bedoradrine free base 是一种新型高选择性 β2-肾上腺素受体激动剂，可用于治疗哮喘和慢性阻塞性肺疾病。
T0948	Adrenalone hydrochloride Adrenalone HCl,肾上腺酮盐酸盐,盐酸肾上腺酮	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Adrenalone hydrochloride (Adrenalone HCl) 是一种多巴胺β氧化酶 (dopamine β oxidase) 抑制剂，结构与去甲肾上腺素转运蛋白 (NET) 配体相似，IC50=36.9 μM。它是一种肾上腺素能 (adrenergic) 激动剂，用作局部血管收缩剂和止血剂。
T20094	Adrenochrome Adraxone	Antioxidant	oxidation-reduction
	Adrenochrome (Adraxone) 是一种细胞毒性分子，可用于杀死细菌。Adrenochrome 是 Epinephrine 的氧化产物。Adrenochrome 是一种可作用于大鼠心脏的冠状动脉收缩化合物，与心脏毒性有关，可用于确定超氧化物歧化酶的活性。Adrenochrome 与可用于神经系统疾病研究，是拟精神病的潜在药物。
T7567L	Adrenorphin 3TFA(88377-68-8(free base)) Metorphamide	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Adrenorphin 3TFA(88377-68-8(free base)) (Metorphamide) 是 μ-opioid 受体 (Ki :12 nM) 的激动剂。
T26760	Bedoradrine sulfate KUR1246,MN 221 sulfate,KUR1246 sulfate,MN221 sulfate,KUR 1246 sulfate,MN-221 sulfate,KUR 1246,KUR-1246 sulfate,MN-221,MN 221,MN221,KUR-1246	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Bedoradrine sulfate（MN-221 sulfate）是一种超选择性β2激动剂，可用于治疗哮喘加重和慢性阻塞性肺病。
TP1244L1	Adrenocorticotropic Hormone (ACTH) (1-10), human acetate Adrenocorticotropic Hormone (ACTH) (1-10), human acetate(2791-05-1 Free base)	Others	Others
	Adrenocorticotropic Hormone (ACTH) (1-10), human acetate 是促肾上腺皮质激素的一个片段。 Adrenocorticotropic Hormone (ACTH) (1-10), human acetate 仅在 100 和 1000 nM 时具有较弱的 α-MSH 效力。
T26939	Cadralazine ISF 2469,卡屈嗪,ISF-2469,ISF2469	Others	Others
	Cadralazine (ISF 2469) 是一种外周小动脉血管扩张剂，可用于作为抗高血压药物的研究。
T1308	Orphenadrine hydrochloride Mebedrol,Mephenamin,盐酸邻甲苯海拉明	Sodium Channel; NMDAR; Norepinephrine; iGluR; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience
	Orphenadrine hydrochloride (Mephenamin) 是一种非竞争性的NMDA 受体拮抗剂, Ki=6.0 ± 0.7 μM。
T2206	Quadrol N,N,N′,N′-Tetrakis(2-hydroxypropyl)ethylenediamine,EDTP,依的托,Edetol	Others	Others
	Quadrol (EDTP) 是一种免疫刺激剂，是潜在的能够加速伤口愈合的有用药物。
T10003	α1 adrenoceptor-MO-1	Others	Others
	α1 adrenoceptor-MO-1（S 对映体）对α1肾上腺素受体具有亲和力，具有抗α-肾上腺素能和镇痛作用。α1 adrenoceptor-MO-1比R 对映体更具活性。
T76664	Adropin (34-76) (human, mouse, rat)
	Adropin (34-76) (human, mouse, rat) 是一种多肽，可减轻肝纤维化和胰岛素抵抗，而不依赖于肥胖或食物摄入。
TP1257L	Adrenomedullin (AM) (22-52), human acetate Adrenomedullin (AM) (22-52), human acetate（159899-65-7 Free base）	CGRP Receptor	GPCR/G Protein; Neuroscience
	Adrenomedullin (AM) (22-52), human acetate 是猫后肢血管床中 CGRP 受体和肾上腺髓质素受体的拮抗剂。
T7556	Fadrozole hydrochloride CGS 16949A,盐酸法倔唑	Aromatase	Endocrinology/Hormones
	Fadrozole hydrochloride (CGS 16949A) 是一种选择性的、有效，和非甾体类的芳香化酶抑制剂(IC50:6.4 nM)。
T8231	Adrenocorticotropic Hormone (ACTH) (1-39), human ACTH (1-39), human,丝拉克肽	Others	Others
	Adrenocorticotropic Hormone (ACTH) (1-39), human (ACTH (1-39), human) 是黑皮质素受体激动剂。
TQ0053	Fadraciclib CYC065	CDK	Cell Cycle/Checkpoint
	Fadraciclib (CYC065) 是一种口服有效的 ATP 竞争性的CDK2/CDK9激酶抑制剂，IC50分别为 5 和 26 nM。
T7627L	Adrenocorticotropic Hormone (ACTH) (4-10) TFA Adrenocorticotropic Hormone (ACTH) (4-10) TFA(4037-01-8(free base)),Acth (4-10)	Melanocortin Receptor	GPCR/G Protein; Neuroscience
	Adrenocorticotropic Hormone (ACTH) (4-10) TFA (Acth (4-10)) 是一种有效的黑皮质素 (MC4R) 受体激动剂。
T0366	Cefadroxil BL-S 578,头孢羟氨苄	Antibacterial; Antibiotic	Microbiology/Virology
	Cefadroxil (BL-S 578) 是头孢菌素类广谱抗生素，有效抑制革兰氏阳性和阴性菌感染。
T0871	Noradrenaline bitartrate	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Noradrenaline bitartrate 直接作用于 α 和 β 肾上腺素能受体。它是去甲肾上腺素的酒石酸氢盐，去甲肾上腺素是一种合成苯乙胺，可模拟内源性去甲肾上腺素的拟交感神经作用。临床上，去甲肾上腺素用作外周血管收缩剂，通过其α-肾上腺素能作用导致动脉和静脉床收缩。它还被用作通过其 β-1 肾上腺素能作用介导的强效正性肌力和变时性心脏刺激剂。
T10250	ADRA1D receptor antagonist 1 HCl ADRA1D receptor antagonist 1 HCl（1191908-24-3 free base）	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	ADRA1D receptor antagonist 1 HCl 是一种具有口服活性、高效性和选择性的 α1D 肾上腺素受体拮抗剂（Ki：1.6 nM），具有潜在的抗增殖活性。
T6618	Orphenadrine Citrate Flexon,Flexoject,Banflex,枸酸芬那君,奥芬那君	AChR; iGluR	Membrane transporter/Ion channel; Neuroscience
	Orphenadrine Citrate (Flexon) 是NMDA 受体拮抗剂，Ki 为6.0μM，还是HERG 钾离子通道阻断剂。它是一种骨骼肌松弛剂，它作用于中枢神经系统以产生肌肉松弛作用。
TP1240	Adrenocorticotropic Hormone (ACTH) (18-39), human TFA CLIP (human) (TFA)	Others	Others
	Adrenocorticotropic Hormone (ACTH) (18-39), human TFA (CLIP human TFA) 是一种似皮质促素中叶肽，由垂体中叶的促黑素细胞产生。
T2558	Cladribine 2-chlorodeoxyadenosine,克拉屈滨,2-Chloro-2′-deoxyadenosine,CldAdo,2CdA	Apoptosis; Adenosine deaminase	Apoptosis; Metabolism
	Cladribine (2CdA) 是一种嘌呤核苷类似物，是具有口服活性的腺苷脱氨酶抑制剂。它能作为 DNA 合成的抑制剂，可阻断受损 DNA 的修复。它可抑制 DNA 甲基化，具有抗淋巴瘤活性，可研究血液恶性肿瘤和多发性硬化。
T125154	Quadranoside III	Antioxidant; Antibacterial	Microbiology/Virology; oxidation-reduction
	Quadranoside III 是从 Melissa officinalis 的干燥茎和叶中分离出三萜化合物，具有潜在的抗菌和抗氧化活性。
T38424	(R)-Fadrozole FAD286,(R)-CGS 16949A free base,(R)-Fadrozole
	(R)-Fadrozole ((R)-CGS 16949A; FAD286) is a potent nonsteroidal inhibitor. (R)-Fadrozole also inhibits human placental aromatase (pIC 50 = 6.17) and aldosterone biosynthesis. (R)-Fadrozole reverses cardiac fibrosis in spontaneously hypertensive heart failure rats..
T76473	Adrenotensin (human)
	Adrenotensin (human) (Pro-ADM-153-185 (human)) 是一种肾上腺髓质素前体肽的特定片段，具体为153至185位点。Adrenotensin (ADM)作为一个含有52个氨基酸的多功能肽，隶属于血管活性肽激素CGRP超家族。
TP2214	Adrenomedullin (1-12), human	Others	Others
	Adrenomedullin (AM) (1-12), human, is a peptide with the sequence Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg. Adrenomedullin (AM) (1-12), human, was initially identified as a vasodilator, and as such, it has the ability to relax vascular tone. Other
T76011	Adrenomedullin (16-31), human TFA
	Adrenomedullin(16-31), human TFA 为人类肾上腺髓质素(hADM)之16至31氨基酸片段，对CGRP1受体显示高亲和力。该化合物在大鼠体内可提高全身血压，但对猫无效。
TP1857	Adrenomedullin (AM) (13-52), human
	Adrenomedullin (13-52) is a 40 amino acid peptide with one intramolecular disulfide bridge, Adrenomedullin (13-52) is a high affinity ligand for the adrenomedullin receptor.
T35851	Etzadroxil Ethyl 2-Ethylbutyrate	Antibacterial	Microbiology/Virology
	Etzadroxil (Ethyl 2-Ethylbutyrate) 是一种可口服且具有挥发性的酯化物。Etzadroxil 具有广谱的抗菌活性，可用于治疗由多重耐药细菌引起的尿路感染。
T32536	l-Adrenalin ascorbinate Tonhormon
	l-Adrenalin ascorbinate is a bioactive chemical.
T29674	Adrogolide HCl ABT 431,DAS 431,A-93431.1,ABT 431;ABT-431;ABT431,ABT-431,Adrogolide Hydrochloride,ABT431
	Adrogolide Hydrochloride is a selective dopamine receptor D1 agonist.
T36817	Quadrone
	Quadrone is a sesquiterpene originally isolated from A. terreus. It is cytotoxic to human carcinoma KB cells in vitro (EC50 = 1.3 μg/ml).
T32748	Lidadronic Acid Lidadronate
	Lidadronic Acid is a bioactive chemical.
T10251	Adrenocorticotropic Hormone (ACTH) (1-39), rat TFA ACTH (1-39) (mouse, rat) TFA	Others	Others
	Adrenocorticotropic Hormone (ACTH) (1-39), rat (TFA) is a potent melanocortin 2 receptor (MC2) agonist.
TP1256	Adrenomedullin (AM) (22-52), human TFA 22-52-Adrenomedullin (human) (TFA)
	Adrenomedullin (AM) (22-52), human (22-52-Adrenomedullin human) TFAis a kind of NH2 TFA truncated at the end of the quality of adrenal medullary analogue, is a kind of quality of adrenal medullary receptor antagonist.
T12435	Adriforant hydrochloride PF-3893787 hydrochloride	Others	Others
	Adriforant hydrochloride is an antagonist of histamine H4 receptor.
T80503	Proadrenomedullin (N-20) (bovine, porcine) ProADM N20(bovine, porcine),PAMP-20(bovine, porcine)
	Proadrenomedullin (N-20) (bovine, porcine) 是一种来源于嗜铬细胞的、具有降压及抑制 catecholamine release 的非竞争性肽类。该化合物能显著抑制 PC12 嗜铬细胞瘤细胞的 catecholamine 分泌，显示出 350 nM 的 IC50 值。此外，Proadrenomedullin (N-20) (bovine, porcine) 作为 EC50 约为 270 nM 的阻断剂，能够有效抵抗烟碱能激动剂引起的 catecholamine release 脱敏现象和烟碱相关的信号通道 (22Na+摄取)。
T71150	Incadronic acid
	Incadronate, also known as Cimadronate and YM-175, is a bone resorption inhibitor. Incadronate disodium inhibits macrophage migration to site of inflammation in vivo and proliferation and causes apoptosis in cancer cells in vitro. Incadronate disodium is a bone density conservation, antitumor and anti-inflammatory agent.

化合物

Cat.No: T29670

Synonym: ICRF198,ICRF-198,ADR 925,ICRF 198,ADR925

Target: Endogenous Metabolite

ADR-851 free base

Cat.No: T23642

Synonym: ADR851 free base

Cat.No: T23641

Synonym: ADR882,ADR-882

Cat.No: T23642L

Synonym: Adr-851,Adr 851,Adr851

Cat.No: T6467

Synonym: ADR-529 Hydrochloride,ICRF-187 hydrochloride,ADR-529,右雷佐生盐酸盐,Dexrazoxane HCl,Cardioxane hydrochloride,ICRF-187

Target: Topoisomerase

Cat.No: T22305

Synonym: 右雷佐生,ICRF-187

Target: Others

σ1 Receptor antagonist-1

Cat.No: T9244

Target: Sigma receptor

Truncated ADR58

Cat.No: T74734

Zosuquidar trihydrochloride

Cat.No: T6018

Synonym: 唑喹达三盐酸盐,Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride

Target: P-gp

Cat.No: T3628

Synonym: DDD00107587

Target: DNA/RNA Synthesis

Cat.No: T7197

Target: Aromatase

Cat.No: T68599

Synonym: Orphenadrine (free base)

Target: Sodium Channel, NMDAR, AChR

Cat.No: T70047

Synonym: Bedoradrine free base

Target: Adrenergic Receptor

Adrenalone hydrochloride

Cat.No: T0948

Synonym: Adrenalone HCl,肾上腺酮盐酸盐,盐酸肾上腺酮

Target: Adrenergic Receptor

Cat.No: T20094

Synonym: Adraxone

Target: Antioxidant

Adrenorphin 3TFA(88377-68-8(free base))

Cat.No: T7567L

Synonym: Metorphamide

Target: Opioid Receptor

Bedoradrine sulfate

Cat.No: T26760

Synonym: KUR1246,MN 221 sulfate,KUR1246 sulfate,MN221 sulfate,KUR 1246 sulfate,MN-221 sulfate,KUR 1246,KUR-1246 sulfate,MN-221,MN 221,MN221,KUR-1246

Target: Adrenergic Receptor

Adrenocorticotropic Hormone (ACTH) (1-10), human acetate

Cat.No: TP1244L1

Synonym: Adrenocorticotropic Hormone (ACTH) (1-10), human acetate(2791-05-1 Free base)

Target: Others

Cat.No: T26939

Synonym: ISF 2469,卡屈嗪,ISF-2469,ISF2469

Target: Others

Orphenadrine hydrochloride

Cat.No: T1308

Synonym: Mebedrol,Mephenamin,盐酸邻甲苯海拉明

Target: Sodium Channel, NMDAR, Norepinephrine, iGluR, Histamine Receptor

Cat.No: T2206

Synonym: N,N,N′,N′-Tetrakis(2-hydroxypropyl)ethylenediamine,EDTP,依的托,Edetol

Target: Others

α1 adrenoceptor-MO-1

Cat.No: T10003

Target: Others

Adropin (34-76) (human, mouse, rat)

Cat.No: T76664

Adrenomedullin (AM) (22-52), human acetate

Cat.No: TP1257L

Synonym: Adrenomedullin (AM) (22-52), human acetate（159899-65-7 Free base）

Target: CGRP Receptor

Fadrozole hydrochloride

Cat.No: T7556

Synonym: CGS 16949A,盐酸法倔唑

Target: Aromatase

Adrenocorticotropic Hormone (ACTH) (1-39), human

Cat.No: T8231

Synonym: ACTH (1-39), human,丝拉克肽

Target: Others

Cat.No: TQ0053

Synonym: CYC065

Target: CDK

Adrenocorticotropic Hormone (ACTH) (4-10) TFA

Cat.No: T7627L

Synonym: Adrenocorticotropic Hormone (ACTH) (4-10) TFA(4037-01-8(free base)),Acth (4-10)

Target: Melanocortin Receptor

Cat.No: T0366

Synonym: BL-S 578,头孢羟氨苄

Target: Antibacterial, Antibiotic

Noradrenaline bitartrate

Cat.No: T0871

Target: Adrenergic Receptor

ADRA1D receptor antagonist 1 HCl

Cat.No: T10250

Synonym: ADRA1D receptor antagonist 1 HCl（1191908-24-3 free base）

Target: Adrenergic Receptor

Orphenadrine Citrate

Cat.No: T6618

Synonym: Flexon,Flexoject,Banflex,枸酸芬那君,奥芬那君

Target: AChR, iGluR

Adrenocorticotropic Hormone (ACTH) (18-39), human TFA

Cat.No: TP1240

Synonym: CLIP (human) (TFA)

Target: Others

Cat.No: T2558

Synonym: 2-chlorodeoxyadenosine,克拉屈滨,2-Chloro-2′-deoxyadenosine,CldAdo,2CdA

Target: Apoptosis, Adenosine deaminase

Quadranoside III

Cat.No: T125154

Target: Antioxidant, Antibacterial

Cat.No: T38424

Synonym: FAD286,(R)-CGS 16949A free base,(R)-Fadrozole

Adrenotensin (human)

Cat.No: T76473

Adrenomedullin (1-12), human

Cat.No: TP2214

Target: Others

Adrenomedullin (16-31), human TFA

Cat.No: T76011

Adrenomedullin (AM) (13-52), human

Cat.No: TP1857

Cat.No: T35851

Synonym: Ethyl 2-Ethylbutyrate

Target: Antibacterial

l-Adrenalin ascorbinate

Cat.No: T32536

Synonym: Tonhormon

Adrogolide HCl

Cat.No: T29674

Synonym: ABT 431,DAS 431,A-93431.1,ABT 431;ABT-431;ABT431,ABT-431,Adrogolide Hydrochloride,ABT431

Cat.No: T36817

Lidadronic Acid

Cat.No: T32748

Synonym: Lidadronate

Adrenocorticotropic Hormone (ACTH) (1-39), rat TFA

Cat.No: T10251

Synonym: ACTH (1-39) (mouse, rat) TFA

Target: Others

Adrenomedullin (AM) (22-52), human TFA

Cat.No: TP1256

Synonym: 22-52-Adrenomedullin (human) (TFA)

Adriforant hydrochloride

Cat.No: T12435

Synonym: PF-3893787 hydrochloride

Target: Others

Proadrenomedullin (N-20) (bovine, porcine)

Cat.No: T80503

Synonym: ProADM N20(bovine, porcine),PAMP-20(bovine, porcine)

Incadronic acid

Cat.No: T71150

Cat. No.	Product Name	Target	Signaling Pathways
T19768	γ-Tocotrienol gamma Tocotrienol,gammaTocotrienol,gamma-Tocotrienol,D-gamma-Tocotrienol,Plastochromanol,γ-生育三烯酚	Others	Others
	γ-Tocotrienol (Plastochromanol) 是一种维生素 E 的活性形式。
T19180	Adrenic Acid 二十二碳四烯酸,廿二碳四烯酸,cis-7,10,13,16-Docosatetraenoic acid	Endogenous Metabolite	Metabolism
	Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) 是一种天然的多不饱和脂肪酸，主要存在于肾上腺，肾脏，大脑和脉管系统中。Adrenic Acid 能够调节肾上腺皮质血管的血管紧张度。Adrenic Acid 也是非酒精性脂肪肝疾病的炎症增强剂。
T2207	Adrenosterone 肾上腺甾酮,11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G	Androgen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Adrenosterone (11-ketoandrostenedione) 是一种人内源性代谢物，由肾上腺皮质产生。Adrenosterone 是一种竞争性羟基类固醇脱氢酶 1 抑制剂。它是一种的类固醇激素，具有较弱的雄激素特性。它是一种膳食补充剂，能够减少脂肪并提高肌肉质量。它能够抑制人类癌细胞的转移进展。
T1071L	DL-Adrenaline Hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	DL-Adrenaline Hydrochloride 是天然存在的拟交感神经胺的盐酸盐，具有收缩血管、降低眼内压的活性。
T20173	Noradrenaline tartrate NSC 169106,NSC-169106,l-Noradrenaline d-bitartrate,NSC169106,Norepinephrine bitartrate
	Norepinephrine bitartrate is a precursor of epinephrine. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus.
T5132	9-dihydro-13-acetylbaccatin III 13-乙酰基-9-羟基巴卡丁 III,13-Acetyl-9-dihydrobaccatin III,9-DHAB III	Apoptosis	Apoptosis
	9-dihydro-13-acetylbaccatin III (9-DHAB III) 是一种制备紫杉醇类似物的中间体。
T4085	Paris saponin VII 重楼皂苷 VII,Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII	Apoptosis; BCL; Others; PARP; p38 MAPK; Akt; Caspase; P-gp; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; MAPK; Membrane transporter/Ion channel; Neuroscience; Others; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Paris saponin VII (Dioscini) 是从延龄草的根和根茎中分离的一种甾体皂苷。它减弱线粒体膜电位，增加凋亡相关蛋白的表达，并降低Bcl-2、caspase-9、caspase-3、PARP-1和p-Akt 的蛋白表达水平。它在 K562/ADR 细胞中诱导强烈的自噬，可研究白血病。
T4A2399	Cinobufotalin 华蟾毒它灵,华蟾素	IL Receptor; Akt; MRP; P-gp	Cytoskeletal Signaling; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; PI3K/Akt/mTOR signaling
	Cinobufotalin 是一种从蟾蜍的皮肤分泌物中提取的强心类固醇或丁二烯内酯。它已被用作强心药，利尿药和止血药，也是潜在的抗肺癌药物。
T83368	3,5-Dimethoxy-2,7-phenanthrenediol
	3,5-Dimethoxy-2,7-phenanthrenediol (compound 2)，一種從Combretum laxum根部分離的菲類化合物，對786-0、MCF-7及NCI/ADR-RES人癌細胞系展現出顯著的細胞毒性，其IC50s值分別為73.26 μM、118.40 μM以及83.99 μM。該化合物還表現出自由基清除活性，其IC50為20.4 μM。
TN5153	Torilin	MMP; ERK; IκB/IKK; p38 MAPK; NF-κB; Tyrosinase; Reductase; DNA/RNA Synthesis; JNK	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Endocrinology/Hormones; MAPK; Metabolism; NF-κB; Proteases/Proteasome
	Torilin 是一种睾酮5α还原酶抑制剂，它（IC50=31.7+/-4.23μM）对5α还原酶的抑制作用强于α-亚麻酸（IC50=160.3+/-24.62μM），但弱于非那雄胺（IC50=0.38+/-0.06μM）。Torilin 具有免疫调节、肝脏保护和抗炎特性，它通过限制 TAK1介导的 MAP 激酶和 NF-βB 活化来抑制炎症，它可以减轻关节炎的严重程度，改变 dLN 或关节中的白细胞活化，并恢复血清和脾细胞细胞因子失衡。托利林抑制α-黑素细胞刺激激素激活的 B16黑色素瘤细胞中的黑色素生成，IC（50）值为25μM。Torilin 对枯草芽孢杆菌 ATCC 6633孢子和营养细胞表现出优异的抗菌活性。Torilin 在体内和体外都具有强大的抗血管生成活性，它可能通过抑制肿瘤侵袭来抑制肿瘤发生，逆转癌细胞的多药耐药性，它可以增强阿霉素、长春碱、紫杉醇和秋水仙碱对多药耐药 KB-V1和 MCF7/ADR 细胞的细胞毒性。

天然产物

Cat.No: T19768

Synonym: gamma Tocotrienol,gammaTocotrienol,gamma-Tocotrienol,D-gamma-Tocotrienol,Plastochromanol,γ-生育三烯酚

Target: Others

Cat.No: T19180

Synonym: 二十二碳四烯酸,廿二碳四烯酸,cis-7,10,13,16-Docosatetraenoic acid

Target: Endogenous Metabolite

Adrenosterone

Cat.No: T2207

Synonym: 肾上腺甾酮,11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G

Target: Androgen Receptor, Endogenous Metabolite

DL-Adrenaline Hydrochloride

Cat.No: T1071L

Target: Adrenergic Receptor

Noradrenaline tartrate

Cat.No: T20173

Synonym: NSC 169106,NSC-169106,l-Noradrenaline d-bitartrate,NSC169106,Norepinephrine bitartrate

9-dihydro-13-acetylbaccatin III

Cat.No: T5132

Synonym: 13-乙酰基-9-羟基巴卡丁 III,13-Acetyl-9-dihydrobaccatin III,9-DHAB III

Target: Apoptosis

Paris saponin VII

Cat.No: T4085

Synonym: 重楼皂苷 VII,Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII

Target: Apoptosis, BCL, Others, PARP, p38 MAPK, Akt, Caspase, P-gp, Autophagy

Cat.No: T4A2399

Synonym: 华蟾毒它灵,华蟾素

Target: IL Receptor, Akt, MRP, P-gp

3,5-Dimethoxy-2,7-phenanthrenediol

Cat.No: T83368

Cat.No: TN5153

Target: MMP, ERK, IκB/IKK, p38 MAPK, NF-κB, Tyrosinase, Reductase, DNA/RNA Synthesis, JNK

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02438	AKR1B1 Protein, Human, Recombinant (His) ALDR1,AR,ADR,aldo-keto reductase family 1, member B...	Human	E. coli
	Aldose reductase (AKR1B1) belongs to the aldo/keto reductase superfamily. AKR1B1 is a NADPH-dependent aldo-keto reductase best known as the rate-limiting enzyme of the polyol pathway. Expression of AKR1B1 was the highest in lens and retina. It is the first enzyme in the polyol pathway through which glucose is converted to sorbitol which is important for the function of various organs in the body, and has been implicated in the etiology of diabetic complications. AKR1B1 is quite abundant in the c...
TMPY-02121	CXADR/CAR Protein, Human, Recombinant (His) coxsackie virus and adenovirus receptor,CAR,CXADR,C...	Human	HEK293 Cells
	CXADR/CAR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is P78310-1.
TMPY-00738	CXADR/CAR Protein, Mouse, Recombinant (His & hFc) AW553441,coxsackie virus and adenovirus receptor,MCAR,261020...	Mouse	HEK293 Cells
	CXADR/CAR Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 52 kDa and the accession number is P97792-1.
TMPJ-00237	CXADR/CAR Protein, Mouse, Recombinant (hFc) CVB3 BP,Cxadr,CAR,Coxsackievirus and adenovirus rec...	Mouse	HEK293 Cells
	CXADR/CAR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 50-70 KDa and the accession number is P97792.
TMPH-00288	Adrenodoxin reductase Protein, Bovine, Recombinant (His) Ferredoxin reductase,Adrenodoxin reductase,Ferredox...	Bovine	P. pastoris (Yeast)
	Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. Adrenodoxin reductase Protein, Bovine, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 52.8 kDa and the accession number is P08165.
TMPY-02839	Adrenomedullin Protein, Human, Recombinant (hFc) AM,PAMP,adrenomedullin	Human	HEK293 Cells
	Adrenomedullin consists of 52 amino acids and is a member of the adrenomedullin family. It s a a hypotensive peptide and has 1 intramolecular disulfide bond. It seems that adrenomedullin has a slight homology with the calcitonin gene-related peptide. Adrenomedullin has a highly expression in pheochromocytoma and adrenal medulla. It also can be detected in lung, ventricle and kidney tissues. Adrenomedullin and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been report...
TMPY-00739	CXADR/CAR Protein, Human, Recombinant (His & hFc) CXADR,HCAR,CAR,coxsackie virus and adenovirus recep...	Human	HEK293 Cells
	CXADR/CAR Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 52 kDa and the accession number is P78310-1.
TMPY-01939	CXADR/CAR Protein, Mouse, Recombinant (His) CAR,coxsackie virus and adenovirus receptor,MCAR,AU016810,MC...	Mouse	HEK293 Cells
	CXADR/CAR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.7 kDa and the accession number is P97792-1.
TMPH-00220	Adrenodoxin, mitochondrial Protein, Bovine, Recombinant (His) Hepato-ferredoxin,FDX1,Ferredoxin-1,Adrenodoxin, mi...	Bovine	E. coli
	Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage to produce pregnenolone, the precursor of most steroid hormones. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons. Adrenodoxin, mitochondrial Protein, Bov...
TMPH-00287	Adrenodoxin reductase Protein, Bovine, Recombinant (E. coli, His) Ferredoxin--NADP(+) reductase,ADXR,NADPH:adrenodoxi...	Bovine	E. coli
	Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. Adrenodoxin reductase Protein, Bovine, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 55.8 kDa and the accession number is ...
TMPJ-00236	CXADR/CAR Protein, Mouse, Recombinant (Avi & His), Biotinylated Cxadr,Coxsackievirus and adenovirus receptor homolo...	Mouse	HEK293 Cells
	CXADR/CAR Protein, Mouse, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 30-40 KDa and the accession number is P97792.

重组蛋白

AKR1B1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02438

Species: Human

Expression System: E. coli

CXADR/CAR Protein, Human, Recombinant (His)

Cat.No: TMPY-02121

Species: Human

Expression System: HEK293 Cells

CXADR/CAR Protein, Mouse, Recombinant (His & hFc)

Cat.No: TMPY-00738

Species: Mouse

Expression System: HEK293 Cells

CXADR/CAR Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00237

Species: Mouse

Expression System: HEK293 Cells

Adrenodoxin reductase Protein, Bovine, Recombinant (His)

Cat.No: TMPH-00288

Species: Bovine

Expression System: P. pastoris (Yeast)

Adrenomedullin Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02839

Species: Human

Expression System: HEK293 Cells

CXADR/CAR Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-00739

Species: Human

Expression System: HEK293 Cells

CXADR/CAR Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01939

Species: Mouse

Expression System: HEK293 Cells

Adrenodoxin, mitochondrial Protein, Bovine, Recombinant (His)

Cat.No: TMPH-00220

Species: Bovine

Expression System: E. coli

Adrenodoxin reductase Protein, Bovine, Recombinant (E. coli, His)

Cat.No: TMPH-00287

Species: Bovine

Expression System: E. coli

CXADR/CAR Protein, Mouse, Recombinant (Avi & His), Biotinylated

Cat.No: TMPJ-00236

Species: Mouse

Expression System: HEK293 Cells

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