首页工具

登录

搜索结果

Search Results for " hypoglycemic "

58

抑制剂 & 化合物

23

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T19367	Hypoglycemic agent 1	Others	Others
	Hypoglycemic agent 1 has an action for lowering blood sugar. It acts as a therapeutic and/or prophylactic agent for diabetes.
T8345	Carbutamide	Others	Others
	Carbutamide 是一代磺酰脲，口服具有活性，具有降血糖作用。
T34532	Sari 59-801 Sari-59-801	Others	Others
	Sari 59-801 是具有口服活性的降血糖化合物，能够降低几个物种的血糖，且可以提高大鼠和小鼠的血浆中胰岛素水平。
T15567	Imiglitazar TAK-559	PPAR	DNA Damage/DNA Repair; Metabolism
	Imiglitazar (TAK559)是有效的 PPAR-β/δ受体激动剂，具有降血糖作用。
T0127	Glimepiride Glimperide,HOE-490,格列美脲	Potassium Channel	Membrane transporter/Ion channel
	Glimepiride (HOE-490) 是一种中长效的磺酰脲类抗糖尿病化合物，其 ED50=182 μg/k。
T60715	α-Glucosidase-IN-4	Glucosidase	Metabolism
	α-Glucosidase-IN-4 是一种有效的α- 葡萄糖苷酶 (α-glucosidase)抑制剂，具有降血压和降糖活性。
T1333	Tolazamide 甲磺氮草脲,妥拉磺脲,U-17835	Potassium Channel	Membrane transporter/Ion channel
	Tolazamide (U-17835) 是一种磺脲类降糖药，用于研究 2 型糖尿病，其作用和用途与氯丙酰胺相似。
T1054	Tolbutamide 甲苯磺丁脲,HLS 831	Potassium Channel; Autophagy	Autophagy; Membrane transporter/Ion channel
	Tolbutamide (HLS 831) 是一种磺脲类降糖药，作用和用途与氯丙酰胺相似。
T0150	Hydroxyhexamide 乙酸己脲,(±)-Hydroxyhexamid	Potassium Channel; Drug Metabolite	Membrane transporter/Ion channel; Metabolism
	Hydroxyhexamide ((±)-Hydroxyhexamid) 是Acetohexamide 的活性代谢物, 可用作降血糖药。
T34973	Tyrphostin 8 4-Hydroxybenzylidenemalononitrile	EGFR; GTPase	Angiogenesis; GPCR/G Protein; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) 是一种有效的 GTP 酶抑制剂，对 EGFR 激酶有抑制作用， IC50 值为 560 μM。Tyrphostin 8 可抑制蛋白丝氨酸/苏氨酸钙调磷酸酶 (IC50=21 μM)，增强 Caco-2 细胞中转铁蛋白受体介导的转吞作用，并增加口服胰岛素 - 转铁蛋白的降血糖作用。
T63166L	(S, R)-LSN 3318839 (S, R)-LSN 3318839(Isomer-2764704-18-7)	Glucagon Receptor	GPCR/G Protein

T26982	Cerebrocrast IOS 11212,IOS-11212,IOS11212	Others	Others
	Cerebrocrast (IOS-11212) 是具有抗炎和降血糖活性，促进大鼠肝脏线粒体中 H+ 和 Cl- 的共转运，阻断人血小板活化，可用于研究糖尿病。
T22683	CP-316819 CP 316819,GPi 819	Others	Others
	CP-316819 (GPi 819) 是一种高效的糖原磷酸化酶 (GPase) 抑制剂，具有降血糖作用，抑制 huSMGPa 和 huLGPa，可在低血糖期间维持神经元活性，可用于研究高血糖。
T0191	Linagliptin BI 1356,利格列汀,利拉利汀	Ferroptosis; Proteasome; DPP-4; Autophagy	Apoptosis; Autophagy; Proteases/Proteasome; Ubiquitination
	Linagliptin (BI 1356) 是一种有效的、可口服的、基于二氢嘌呤二酮的二肽基肽酶 4 抑制剂，具有降血糖活性。
T0490	Chlorpropamide Diabinese,氯磺丙脲	ATPase; ABC	Membrane transporter/Ion channel
	Chlorpropamide (Diabinese) 是口服降糖剂，可用于研究非胰岛素依赖型糖尿病。
T62238	AMPK activator 4	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	AMPK activator 4 是一种有效且具有选择性的AMPK激活剂，不抑制线粒体复合物 I。AMPK activator 4 选择性地激活肌肉组织中的 AMPK且剂量依赖性地改善正常小鼠的糖耐量，显著降低 db/db 糖尿病小鼠的空腹血糖水平和改善胰岛素抵抗。AMPK activator 4 具有降血糖作用。
T31976	Glymidine sodium	Others	Others
	Glymidine sodium 是口服有活性的抗糖尿病药物，也是肝脂肪分解的抑制剂。它通过抑制葡萄糖的形成，也对由于内源性脂质动员抑制而导致的丙酮酸氧化升高具有抑制作用。
T71812	Protonstatin-1
	Protonstatin-1可用作降糖剂和治疗阿尔茨海默病的化合物，可抑制IGFIR 激酶的活性，可用于研究癌症。
T0334	Rosiglitazone BRL49653,罗格列酮	Ferroptosis; TRP/TRPV Channel; PPAR; Autophagy	Apoptosis; Autophagy; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism
	Rosiglitazone (BRL49653) 是一种 PPARγ 激动剂、TRPC5 激活剂和 TRPM3 抑制剂，具有口服活性。Rosiglitazone 也是一种降糖剂，是噻唑烷二酮类胰岛素增敏剂。
T1603	Glipizide CP 28720,K 4024,格列吡嗪	Potassium Channel; PPAR; ABC	DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism
	Glipizide (CP 28720) 是一种有效的、具有口服活性的磺酰脲类抗糖尿病试剂 (anti-diabetic agent)，在 2 型糖尿病的研究中具有价值，但不适用于1 型糖尿病。Glipizide 是通过部分阻断郎格汉斯胰岛细胞中 ATP 敏感钾通道 (KATP)发挥活性。
T1112	2-(Hydroxymethyl)pyridine 吡啶甲醇,Piconol	PDE	Metabolism
	2-(Hydroxymethyl)pyridine (Piconol) 可用作有机合成与医药化学中间体，用于刺激性泻药比沙可啶的合成，也可用作具有降血糖活性的吡啶醇。
T1502	Vildagliptin 维达列汀,NVP-LAF 237,维格列汀,LAF237	Apoptosis; Ferroptosis; Proteasome; DPP-4	Apoptosis; Proteases/Proteasome; Ubiquitination
	Vildagliptin (LAF237) 是一种选择性二肽基肽酶IV (DPP-IV) 抑制剂，在人 Caco-2 细胞中抑制 DPP-IV 的IC50为 3.5 nM。它具有出色的口服生物利用度和降血糖活性。
T8221	Insulin (human) INSULIN,甘精胰岛素,胰岛素,Insulin(human)	IGF-1R	Tyrosine Kinase/Adaptors
	Insulin (human) 是一种多肽激素，可以促进糖原的合成，调节血液中的葡萄糖水平。Insulin (human) 具有降血糖活性，临床上用于治疗糖尿病患者的高血糖。
T69146	Suksdorfin	PPAR	DNA Damage/DNA Repair; Metabolism
	Suksdorfin 具有降血糖作用，可促进脂肪细胞分化并增强脂联素的产生，可激活过氧化物酶体增殖物激活受体 γ （PPARγ），可促进脂肪细胞对胰岛素依赖性葡萄糖的摄取，可用于肥胖相关研究。
T0816	Acetohexamide Acetohexamid,醋磺环已脲,Dymelor,醋磺己脲,Gamadiabet	Potassium Channel; NADPH	Membrane transporter/Ion channel; Metabolism
	Acetohexamide (Acetohexamid) 是磺脲类试剂，可刺激胰腺分泌胰岛素，能够用于 2 型糖尿病的相关研究。
T1674	Nateglinide 那格列奈,A4166,Senaglinide	Potassium Channel; Proteasome; PPAR	DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Proteases/Proteasome; Ubiquitination
	Nateglinide (Senaglinide) 是 D-苯丙氨酸的一种衍生物，是口服有效的、短效促胰岛素释放化合物，也是 DPP IV 抑制剂。 Nateglinide 抑制胰岛 β 细胞中 ATP 敏感的 K+通道。Nateglinide 在 2 型糖尿病中具有研究价值。
T24270	KS370G KS-370-G,KS 370 G,Caffeic Acid Phenethyl Amide
	KS370G (Caffeic Acid Phenethyl Amide) 抑制 UUO 诱导的肾纤维化标志物表达。KS370G 是一种具有口服活性的降糖和心血管保护剂，可减少梗阻肾脏中胶原蛋白的沉积，并显著降低肾脏炎症趋化因子/粘附分子和单核细胞标志物的表达，改善压力过载小鼠心脏左室肥厚和功能。KS370G 可用于研究肾阻塞性肾病。
T19710	Ciglitazone Ciglitazona,U 63287,ADD3878,ADD-3878,U-63287,ADD 3878	Apoptosis; p38 MAPK; PPAR	Apoptosis; DNA Damage/DNA Repair; MAPK; Metabolism
	Ciglitazone (ADD 3878) 是一种强效和选择性的PPARγ激动剂(EC50：3μM)和口服降糖药。Ciglitazone 抑制th17细胞的增殖和分化，降低胰岛素水平、血管内皮生长因子的产生和血压，诱导胃癌细胞的细胞周期停止。Ciglitazone 能诱导负鼠肾上皮细胞的凋亡，激活p38 MAPK 和凋亡诱导因子(AIF)的核转位。 Ciglitazone 在肥胖症和高血糖症的动物模型中表现出降血糖活性。
T0242	Sitagliptin 西他列汀,MK0431,西格列汀	Proteasome; DPP-4; Autophagy	Autophagy; Proteases/Proteasome; Ubiquitination
	Sitagliptin (MK0431) 是一种有效的 DPP4抑制剂，在 Caco-2 细胞中，IC50值为 19 nM。它是一种新型口服降糖药，可单独使用或与二甲双胍或噻唑烷二酮联合用于治疗 2 型糖尿病。
T13712	Glyparamide	Others	Others
	Glyparamide is a chlorophenyl-containing sulfonylurea with hypoglycemic activity.
T32857	Lonchocarpene
	Lonchocarpene is a hypoglycemic agent From the Amazonian plant Deguelia rufescens var. urucu.
T11431	Glycosidase-IN-2	Others	Others
	Glycosidase-IN-2 is a glycosidase inhibitor with hypoglycemic activity.
T13711	Glyhexamide Subose,SQ 15860,Serbose	Others	Others
	Glyhexamide is an effective hypoglycemic compound.
T27415	Gliamilide CP-27,634,CP27,634,CP 27,634
	Gliamilide is a high-potency sulfamylurea hypoglycemic agent.
T34537	Saudin
	Saudin is a naturally occurring hypoglycemic diterpene.
T0371L	Gliquidone sodium
	Gliquidone sodium is a hypoglycemic sulfonylurea which may protect the liver from injury from diabetes.
T13478	β-glycosidase-IN-1	Integrin	Cytoskeletal Signaling
	β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.
T69191	Pemaglitazar
	Pemaglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha and gamma agonist, with hypoglycemic activity.
T63404	Xelaglifam
	Xelaglifam 是 G 蛋白偶联受体 40 (GPR40) 的有效激动剂，表现出降血糖作用。
T71296	4-Aaqb
	4-Aaqb, also known as OB-318, is a natural inhibitor of the autophagy pathway, enhancing immune function, suppressing MAPK and NFκB, showing anti-inflammatory, hypoglycemic, vasorelaxative, and antiproliferative activities.
T68745	U 56324
	U-56324 is a hypoglycemic agent derived from nicotinic acid. It was found to inhibit the activity of ATP-sensitive potassium channels in excised patches from mouse pancreatic B-cells.
T11430	Glycosidase-IN-1	Others	Others
	Glycosidase-IN-1 is a glycosidase inhibitor synthesized from D-mannose with hypoglycemic activity. It can be used to synthesize some immunosuppressive agents and β-glucosidase inhibitors.
T40694	4-(3-Methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid
	4-(3-Methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid exhibits hypoglycemic activity and operates through a mechanism dependent on the response to oral glucose overload.
T68196	Aminocarnitine
	Aminocarnitine is an inhibitor of fatty acid oxidation that acts as a hypoglycemic and antiketogenic compound. It alters lipidic metabolism by inhibiting carnitine acetyltransferase (CAT) and carnitine palmitoyltransferase (CPT).
T68567	AMG-131 besylate
	AMG-131 besylate is a hypoglycemic agent. It is a potent PPARγ partial agonist that displays robust glucose-lowering activity in rodent models of diabetes while exhibiting a reduced side-effects profile compared to marketed TZDs.
T25283	Cytochrome P450 2C9 Cyp2C9,Human cytochrome P450 2C9,Cytochrome P 450 2C9,S-Mephenytoin 4-hydroxylase
	Cytochrome P450 2C9 is a cytochrome P-450 subtype that possesses specificity for acidic xenobiotics. It oxidizes a wide range of important clinical drugs under the categories of nonsteroidal anti-inflammatory agents, anticoagulants, hypoglycemic agents, a
T35265	YM-440 YM440,YM 440
	YM-440 is a novel hypoglycemic agent, an insulin sensitizer, that may be used for the treatment of type 2 diabetes mellitus by reducing glucose 6-phosphatase activity in obese Zucker rats and inhibiting liver glucose output through gluconeogenesis.
T34767	TA-1887 TA 1887,TA1887
	TA-1887 is a new type of selective inhibitor of sglt2 for the treatment of type 2 diabetes. It has a significant hypoglycemic effect in KK (HF-KK) mice fed a high-fat diet. TA-1887 has good pharmacokinetic characteristics and significantly increases UGE
T6203L	Saxagliptin hydrochloride BMS477118,Saxagliptin,BMS 477118,Saxagliptin HCl,BMS-477118
	Saxagliptin is a new oral hypoglycemic of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones and reducing fasting and postprandial glucose conce
T68098	Midaglizole (±)-DG5128 free base,DG5128 free base,(±)-DG5128 free base ; DG5128 free base
	Midaglizole ((±)-DG5128 free base, DG5128 free base) 是一种有效的α2-adrenoceptor 拮抗剂。Midaglizole 是一种降血糖药。Midaglizole 在具有升高血压并降低血糖水平的作用。

化合物

Hypoglycemic agent 1

Cat.No: T19367

Target: Others

Cat.No: T8345

Target: Others

Cat.No: T34532

Synonym: Sari-59-801

Target: Others

Cat.No: T15567

Synonym: TAK-559

Target: PPAR

Cat.No: T0127

Synonym: Glimperide,HOE-490,格列美脲

Target: Potassium Channel

α-Glucosidase-IN-4

Cat.No: T60715

Target: Glucosidase

Cat.No: T1333

Synonym: 甲磺氮草脲,妥拉磺脲,U-17835

Target: Potassium Channel

Cat.No: T1054

Synonym: 甲苯磺丁脲,HLS 831

Target: Potassium Channel, Autophagy

Hydroxyhexamide

Cat.No: T0150

Synonym: 乙酸己脲,(±)-Hydroxyhexamid

Target: Potassium Channel, Drug Metabolite

Cat.No: T34973

Synonym: 4-Hydroxybenzylidenemalononitrile

Target: EGFR, GTPase

(S, R)-LSN 3318839

Cat.No: T63166L

Synonym: (S, R)-LSN 3318839(Isomer-2764704-18-7)

Target: Glucagon Receptor

Cat.No: T26982

Synonym: IOS 11212,IOS-11212,IOS11212

Target: Others

Cat.No: T22683

Synonym: CP 316819,GPi 819

Target: Others

Cat.No: T0191

Synonym: BI 1356,利格列汀,利拉利汀

Target: Ferroptosis, Proteasome, DPP-4, Autophagy

Cat.No: T0490

Synonym: Diabinese,氯磺丙脲

Target: ATPase, ABC

AMPK activator 4

Cat.No: T62238

Target: AMPK

Glymidine sodium

Cat.No: T31976

Target: Others

Cat.No: T71812

Cat.No: T0334

Synonym: BRL49653,罗格列酮

Target: Ferroptosis, TRP/TRPV Channel, PPAR, Autophagy

Cat.No: T1603

Synonym: CP 28720,K 4024,格列吡嗪

Target: Potassium Channel, PPAR, ABC

2-(Hydroxymethyl)pyridine

Cat.No: T1112

Synonym: 吡啶甲醇,Piconol

Target: PDE

Cat.No: T1502

Synonym: 维达列汀,NVP-LAF 237,维格列汀,LAF237

Target: Apoptosis, Ferroptosis, Proteasome, DPP-4

Insulin (human)

Cat.No: T8221

Synonym: INSULIN,甘精胰岛素,胰岛素,Insulin(human)

Target: IGF-1R

Cat.No: T69146

Target: PPAR

Cat.No: T0816

Synonym: Acetohexamid,醋磺环已脲,Dymelor,醋磺己脲,Gamadiabet

Target: Potassium Channel, NADPH

Cat.No: T1674

Synonym: 那格列奈,A4166,Senaglinide

Target: Potassium Channel, Proteasome, PPAR

Cat.No: T24270

Synonym: KS-370-G,KS 370 G,Caffeic Acid Phenethyl Amide

Cat.No: T19710

Synonym: Ciglitazona,U 63287,ADD3878,ADD-3878,U-63287,ADD 3878

Target: Apoptosis, p38 MAPK, PPAR

Cat.No: T0242

Synonym: 西他列汀,MK0431,西格列汀

Target: Proteasome, DPP-4, Autophagy

Cat.No: T13712

Target: Others

Cat.No: T32857

Glycosidase-IN-2

Cat.No: T11431

Target: Others

Cat.No: T13711

Synonym: Subose,SQ 15860,Serbose

Target: Others

Cat.No: T27415

Synonym: CP-27,634,CP27,634,CP 27,634

Cat.No: T34537

Gliquidone sodium

Cat.No: T0371L

β-glycosidase-IN-1

Cat.No: T13478

Target: Integrin

Cat.No: T69191

Cat.No: T63404

Cat.No: T71296

Cat.No: T68745

Glycosidase-IN-1

Cat.No: T11430

Target: Others

4-(3-Methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid

Cat.No: T40694

Cat.No: T68196

AMG-131 besylate

Cat.No: T68567

Cytochrome P450 2C9

Cat.No: T25283

Synonym: Cyp2C9,Human cytochrome P450 2C9,Cytochrome P 450 2C9,S-Mephenytoin 4-hydroxylase

Cat.No: T35265

Synonym: YM440,YM 440

Cat.No: T34767

Synonym: TA 1887,TA1887

Saxagliptin hydrochloride

Cat.No: T6203L

Synonym: BMS477118,Saxagliptin,BMS 477118,Saxagliptin HCl,BMS-477118

Cat.No: T68098

Synonym: (±)-DG5128 free base,DG5128 free base,(±)-DG5128 free base ; DG5128 free base

Cat. No.	Product Name	Target	Signaling Pathways
T8319	Butyl isobutyl phthalate ButylIsobutylPhthalate,邻苯二甲酸-1-丁酯-2-异丁酯	Glucosidase	Metabolism
	Butyl isobutyl phthalate (ButylIsobutylPhthalate) 是一种非竞争性 α-葡萄糖苷酶抑制剂，IC50=38 μM，可以从海带的根状茎中分离得到。它具有降血糖作用，可用于糖尿病相关的研究。
T3776	Rhapontigenin 丹叶大黄素,Protigenin	P450; Antibacterial; Antifungal	Metabolism; Microbiology/Virology
	Rhapontigenin (Protigenin) 是一种基于机制的选择性细胞色素 P450 1A1 (IC50: 400 nM) 灭活剂。它是一种芳烃羟化酶，可激活作为致癌物质的多环芳烃。它是白藜芦醇的天然类似物，具有抗癌，抗氧化剂，抗真菌和抗菌活性。
T2780	Catalpol 梓醇,Catalpinoside,Digitalis purpurea L	Others; HBV	Microbiology/Virology; Others
	Catalpol (Catalpinoside) 是一种在Rehmannia glutinosa 中发现的鸢尾花苷，具有神经保护、降血糖、抗癌、抗痉挛、抗氧化、抗HBV 和抗肝炎病毒作用。
T38475	2,6-Dimethylpyrazine	Others	Others
	2,6-Dimethylpyrazine 是食品工业中不可缺少的调味添加剂，也是生产降糖和抗脂解化合物的重要底物。
T2756	Swertiamarin 獐牙菜苦苷,獐牙菜苦甙,Swertiamaroside	Others	Others
	Swertiamarin (Swertiamaroside) 是一种裂环烯醚萜苷，在 Enicostemma Species 属植物中发现，具有降血糖和降血脂作用。
T2889	Isoferulic acid Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate,异阿魏酸	Influenza Virus; Adrenergic Receptor	GPCR/G Protein; Microbiology/Virology; Neuroscience
	Isoferulic acid (Hesperetate) 是一种肉桂酸衍生物，有抗糖尿病活性和抗流感病毒活性。它能结合并激活 α1-肾上腺素能受体，增强 β-内啡肽的分泌并增加体外葡萄糖的使用。
TN2326	(Z)-Butylidenephthalide (Z)-3-Butylidenephthalide	Glucosidase	Metabolism
	(Z)-Butylidenephthalide ((Z)-3-Butylidenephthalide) 具有抗肿瘤和降血糖作用，能有效抑制胶质瘤的肿瘤生长，抑制 R-葡萄糖苷酶活性。
TN2429	Capsiate	Antioxidant; TRP/TRPV Channel	Membrane transporter/Ion channel; oxidation-reduction
	Capsiate 是一种具有口服活性的 TRPV1 激动剂，是非刺激性辣椒素类似物，可作为抗过敏剂，具有抗炎、抗氧、降糖和抑制血管生成活性。
TJS0928	Calenduloside E 去葡萄糖竹节参皂苷,Silphioside F	Others	Others
	Calenduloside E (Silphioside F) 是从辽东楤木中提取的一种五环三萜皂苷。它靶向热休克蛋白90 (Hsp90) ，具有抗凋亡作用。
TQ0298	Fagomine D-Fagomine	ROS; glycosidase	Immunology/Inflammation; Metabolism
	Fagomine (D-Fagomine) 是一种温和的糖苷酶 (glycosidase) 抑制剂，是1-脱氧野尻霉素（DNJ）的类似物，具有降血糖活性，Fagomine 降低了细胞内活性氧（ROS）的产生和丙二醛（MDA）水平。
T3665	Tectoridin 射干苷,Shekanin	Estrogen Receptor/ERR; Reductase	Endocrinology/Hormones; Metabolism
	Tectoridin (Shekanin) 是分离自 Maackia amurensis 中的异黄酮，是一种植物雌激素，能够激活雌激素和甲状腺激素受体。它通过 ER 依赖性基因组途径和 GPR30 依赖性非基因组途径发挥雌激素作用。
T5716	4'-Methoxyresveratrol 白藜芦醇-4'-甲醚,4'-O-Methylresveratrol	advanced glycation end products	Others
	4'-Methoxyresveratrol (4'-O-Methylresveratrol) 是一种多酚类化合物，来源于双翅目植物中，具有抗雄激素、抗真菌和抗炎症作用。它能抑制 RAGE- 介导的 MAPK/NF-κB 信号通路，并激活 NLRP3 炎性体，从而缓解 AGE- 诱导的炎症。
TN4883	Quinine sulfate dihydrate 奎宁树	Others	Others
	Quinine sulfate dihydrate 在钾通道阻滞剂中起主要作用。它也被用作抗疟疾、抗胆碱能、抗高血压和降糖药。它抑制线粒体atp 调节的钾通道。它也被用来研究生物结晶血红素，血红素，在疟疾寄生虫的代谢和研究血红素(FP)复合物的毒性。
T6S1597	Mulberroside A 桑皮苷 A,桑皮苷A	TNF; Tyrosinase; Interleukin	Apoptosis; Immunology/Inflammation; Proteases/Proteasome
	Mulberroside A 是桑中的一种主要活性成分，可降低TNF-α、IL-1β和IL-6的表达，抑制 NALP3、caspase-1 和 NF-κB 的激活以及 ERK、JNK 和 p38 的磷酸化。它抑制蘑菇酪氨酸酶，具有抗炎和抗细胞凋亡作用。
T4S0797	Berberine 小檗碱,Berberin,Umbellatine,黄连素	Reactive Oxygen Species; Topoisomerase; Endogenous Metabolite; Antibacterial; Antibiotic; Autophagy	Autophagy; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Berberine (Umbellatine) 是从中草药黄连中分离出来的一种生物碱抗生素。它诱导活性氧生成并抑制 DNA 拓扑异构酶，具有抗肿瘤特性。
TWS1613	Erioside 桑皮苷B,mulberroside B	Others	Others
	Erioside (mulberroside B) 存在于Lasiosiphon eriocephalus 中，有镇咳、平喘、降血糖、抗肿瘤、治疗痛风的功效。
TN4793	Pinoresinol diacetate	Glucokinase	Metabolism
	Pinoresinol diacetate inhibits the enzyme α-glucosidase in vitro and may therefore act as a hypoglycemic agent.
TN1943	Momordicoside G	Others	Others
	Momordicosides K and L, the main bitter taste triterpene glycosides in Bitter melon; and bitter melon has been reported to have hypoglycemic, anti atherogenic and anti HIV activities.
T81093	Sterebin F
	Sterebin F, 一种甾类化合物，来源于Stevia rebaudiana叶的分离提取，表现出降血糖的活性。
TN1368	Alisol C	Others	Others
	Alisol C can improve glucose uptake in Hep G2 cells, it may be one of the therapeutic material basis in hypoglycemic activities in A. orientalis. Alisol C,16,23-oxido-alisol B and alisol O in Zexie may cause nephrotoxicity.
TN3692	Conduritol A	TNF	Apoptosis
	Conduritol A has a hypoglycemic effect, can have an effect on regulating the metabolism of blood lipid, free-radical scavenging, enhancing the antioxidant ability, potentiating immune function; it also can markedly prevent the diabetic rats from getting c
T79937	Mortatarin F	Glucosidase	Metabolism
	Mortatarin F (Compound 1) 是一种具有戊烯基化类黄酮结构的葡萄糖苷酶抑制剂，其IC50值为8.7 μΜ。该化合物可从桑叶中提取，并应用于研究降低血糖效果。
TN1874	Liriodendrin 鹅掌楸苦素	ATPase; Potassium Channel; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel
	Liriodendrin 调节肺部炎症、NF-kB (p65) 的磷酸化和血管内皮生长因子 (VEGF) 的表达。Liriodendrin 具有抗炎、镇痛、降血糖活性，在脓毒症引起的急性肺损伤中起保护作用。

天然产物

Butyl isobutyl phthalate

Cat.No: T8319

Synonym: ButylIsobutylPhthalate,邻苯二甲酸-1-丁酯-2-异丁酯

Target: Glucosidase

Cat.No: T3776

Synonym: 丹叶大黄素,Protigenin

Target: P450, Antibacterial, Antifungal

Cat.No: T2780

Synonym: 梓醇,Catalpinoside,Digitalis purpurea L

Target: Others, HBV

2,6-Dimethylpyrazine

Cat.No: T38475

Target: Others

Cat.No: T2756

Synonym: 獐牙菜苦苷,獐牙菜苦甙,Swertiamaroside

Target: Others

Isoferulic acid

Cat.No: T2889

Synonym: Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate,异阿魏酸

Target: Influenza Virus, Adrenergic Receptor

(Z)-Butylidenephthalide

Cat.No: TN2326

Synonym: (Z)-3-Butylidenephthalide

Target: Glucosidase

Cat.No: TN2429

Target: Antioxidant, TRP/TRPV Channel

Calenduloside E

Cat.No: TJS0928

Synonym: 去葡萄糖竹节参皂苷,Silphioside F

Target: Others

Cat.No: TQ0298

Synonym: D-Fagomine

Target: ROS, glycosidase

Cat.No: T3665

Synonym: 射干苷,Shekanin

Target: Estrogen Receptor/ERR, Reductase

4'-Methoxyresveratrol

Cat.No: T5716

Synonym: 白藜芦醇-4'-甲醚,4'-O-Methylresveratrol

Target: advanced glycation end products

Quinine sulfate dihydrate

Cat.No: TN4883

Synonym: 奎宁树

Target: Others

Cat.No: T6S1597

Synonym: 桑皮苷 A,桑皮苷A

Target: TNF, Tyrosinase, Interleukin

Cat.No: T4S0797

Synonym: 小檗碱,Berberin,Umbellatine,黄连素

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

Cat.No: TWS1613

Synonym: 桑皮苷B,mulberroside B

Target: Others

Pinoresinol diacetate

Cat.No: TN4793

Target: Glucokinase

Momordicoside G

Cat.No: TN1943

Target: Others

Cat.No: T81093

Cat.No: TN1368

Target: Others

Cat.No: TN3692

Target: TNF

Cat.No: T79937

Target: Glucosidase

Cat.No: TN1874

Synonym: 鹅掌楸苦素

Target: ATPase, Potassium Channel, Prostaglandin Receptor

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼