97
12
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4509 |
Inositol nicotinate
Inositol niacinate,Hexanicotol,Myo-Inositol hexanicotinate,Mesotal,肌醇烟酸酯,Dilexpal,Inositol hexanicotinate |
Others | Others |
Inositol nicotinate (Mesotal) 是一种血管扩张剂,可用于研究外周动脉疾病。 | |||
T35933 |
D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt)
D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt),Ins(1,4,5,6)-P4 |
||
D-myo-Inositol-1,4,5,6-tetrahosphate (sodium salt) (Ins(1,4,5,6)-P4) is one of several different inositol oligophosphate isomers implicated in signal transduction. Production of Ins(1,4,5,6)-P4 by intestinal epithelial cells increases approximately 2-14 fold, depending on the strain and incubation time, following infection with Salmonella.[1] D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt) (Ins(1,4,5,6)-P4) is one of several different inositol oligophosphate isomers implicated in signal tran... | |||
T35935 |
D-myo-Inositol-1,4,5-triphosphate trisodium
Inositol 1,4,5-trisphosphate trisodium,Ins(1,4,5)-P3 trisodium,D-myo-Inositol-1,4,5-triphosphate (sodium salt),Ins(1,4,5)P3 |
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
D-myo-Inositol-1,4,5-triphosphate trisodium (Inositol 1,4,5-trisphosphate trisodium) 是由磷脂酶 C 介导的磷脂酰肌醇-4,5-二磷酸酯水解在细胞中产生的第二信使。D-myo-Inositol-1,4,5-triphosphate (sodium salt)与 Ins(1,4,5)P3受体结合,会导致钙通道的打开和细胞内钙的增加。 | |||
T35938 |
D-myo-Inositol-4-phosphate (ammonium salt)
|
||
D-myo-Inositol-4-phosphate (Ins(4)P1) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-diphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intr... | |||
T37057 |
D-myo-Inositol-1,2-diphosphate (sodium salt)
|
||
Ins(1,2)P2 (sodium salt) is one of the many inositol phosphate (InsP) isomers that could act as small, soluble second messengers in the transmission of cellular signals. The most studied InsP Ins(1,4,5)P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(1,2)P2 (te... | |||
T37060 |
D-myo-Inositol-1,3-diphosphate (sodium salt)
|
||
D-myo-Inositol-1,3-phosphate (Ins(1,3)P) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3 is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in in... | |||
T36069 | L-myo-Inositol-1,4,5-triphosphate (sodium salt) | ||
Ins(1,4,5)P3 is an isomer of the biologically important D-myo-inositol-1,4,5-triphosphate. Unlike its isomer, Ins(1,4,5)P3 does not evoke a rise in intracellular calcium when added to cells. It is not known if Ins(1,4,5)P3 can act as a competitive inhibitor of biologically-active inositol phosphates. | |||
T35936 |
D-myo-Inositol-1,4,6-triphosphate (sodium salt)
|
||
D-myo-Inositol-1,4,6-phosphate (Ins(1,4,6)-P3) is a member of the inositol phosphate (InsP) family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)-P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)-P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in int... | |||
T37058 |
D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)
|
||
D-myo-Inositol-1,3,4,5-tetraphosphate (Ins(1,3,4,5)-P4) is formed by the phosphorylation of Ins(1,4,5)P3 by inositol 1,4,5-triphosphate 3-kinase. Ins(1,3,4,5)-P4 increases intracellular calcium levels by two distinct mechanisms: opening calcium channels on both the endoplasmic reticulum to release calcium from internal stores and on the plasma membrane to allow the influx of calcium from outside the cell. | |||
T35937 |
D-myo-Inositol-1,5,6-triphosphate (sodium salt)
|
||
The inositol phosphates are a family of mono- to poly-phosphorylated compounds that act as messengers, regulating cellular functions including cell cycling, apoptosis, differentiation, andmotility. D-myo-Inositol-1,5,6-triphosphate is an intermediate compound, produced by the dephosphorylation of various inositol-tetrakisphosphate forms. The triphosphate can be further metabolized to produce inositol-biphosphate mediators. The biological roles of D-myo-inositol-1,5,6-triphosphate remain to be de... | |||
T35934 |
D-myo-Inositol-1,4,5-triphosphate (potassium salt)
|
||
D-myo-Inositol-1,4,5-triphosphate (Ins(1,4,5)P3) is a second messenger produced in cells by phospholipase C (PLC) mediated hydrolysis of phosphatidyl inositol-4,5-biphosphate. It binds to one of several Ins(1,4,5)P3 receptors, each containing a calcium channel domain. Binding of Ins(1,4,5)P3 to the receptor results in opening of the calcium channels and an increase in intracellular calcium. | |||
T37059 |
D-myo-Inositol-1,3,4,6-tetraphosphate (ammonium salt)
|
||
The inositol phosphates (IPs) are a family of molecules produced by altering the phosphorylation status of each of the six carbons on the cyclic inositol structure. They act as second messengers, regulating a wide array of cellular functions. D-myo-inositol-1,3,4,6-tetraphosphate(Ins(1,3,4,6)-P4) largely acts an intermediate, serving as substrate for inositol-1,3,4,6-tetraphosphate 5-kinase to produce inositol-1,3,4,5,6-pentaphosphate, or inositol-1,3,4,6-tetraphosphate 2-kinase to give inositol... | |||
T77247 |
D-myo-Inositol 4-monophosphate
|
||
D-myo-Inositol 4-mono-phos-phate 是一种生化试剂,可作为生物材料或有机化合物,用于生命科学相关研究。 | |||
T83390 |
2-C-methylene-myo-inositol oxide
NSC 45109 |
||
2-C-methylene-myo-inositol oxide (NSC 45109)是一种诱导裂糖酵母假菌丝形成的肌醇衍生物。 | |||
TQ0076 |
KIRA6
|
IRE1 | Cell Cycle/Checkpoint |
KIRA6 是一种 IRE1α RNase 激酶的有效抑制剂,IC50为0.6 µM。它可以触发细胞凋亡反应。 | |||
T12071 |
MKC9989
|
IRE1 | Cell Cycle/Checkpoint |
MKC9989 是一种羟基芳基醛 (HAA) 的抑制剂,抑制 IRE1α的 IC50值在 0.23 到 44 μM 之间。 | |||
T3654 |
APY29
|
IRE1 | Cell Cycle/Checkpoint |
APY29 是 IRE1α 的变构调节剂;抑制 IRE1α 自磷酸化,IC50值为 280 nM,并激活 IRE1α RNase 活性。 | |||
T6363 |
4μ8C
IRE1 Inhibitor III |
IRE1 | Cell Cycle/Checkpoint |
4μ8C (IRE1 Inhibitor III) 是一种有效且特异性的 IRE1α 抑制剂。 | |||
T6681 |
STF-083010
STF083010 |
IRE1 | Cell Cycle/Checkpoint |
STF-083010 是一种 IRE1α 核酸内切酶的选择性抑制剂。 | |||
T19266 |
Ins(1,4,5)-P3 hexapotassium salt
1,4,5-IP3 hexapotassium salt,D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt |
Others | Others |
D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt is promotes endoplasmic The second messenger of net calcium ions. | |||
TQ0101 |
MKC3946
|
IRE1 | Cell Cycle/Checkpoint |
MKC3946 是一种有效的可溶性 IRE1α 抑制剂,可在多发性骨髓瘤细胞系中引发适度的生长抑制,可用于癌症研究。 | |||
T11488 |
GSK2850163
|
IRE1 | Cell Cycle/Checkpoint |
GSK2850163 是新型的肌醇需要酶-1α (IRE1α) 抑制剂,抑制 IRE1α 激酶活性的 IC50为 20nM,对 RNA 酶活性也有抑制活性,IC50为200 nM。 | |||
T15594 |
MKC8866
|
IRE1 | Cell Cycle/Checkpoint |
MKC8866 是一种选择性IRE1 RNase 抑制剂,在体外的IC50为 0.29 μM,是水杨醛类似物。 它抑制乳腺癌细胞中的 IRE1 RNase,导致促肿瘤因子的产生减少,并且可以抑制前列腺癌 (PCa) 肿瘤的生长。它强烈抑制二硫苏糖醇诱导的 XBP1s 表达,EC50为 0.52 μM。 | |||
T11762L |
Kira8
AMG-18 |
IRE1 | Cell Cycle/Checkpoint |
Kira8 (AMG-18) 是一种单选择性 IRE1α 抑制剂,可变构减弱 IRE1α RNase 活性,IC50为 5.9 nM。 | |||
T9349 |
IXA4
|
IRE1 | Cell Cycle/Checkpoint |
IXA4 是一种高选择性、无毒的 IRE1/XBP1s 激活剂,通过激活 IRE1 来减少 APP 的分泌。它刺激的 IRE1 激活也增强了胰腺功能。 | |||
T9564 |
IRE1α kinase-IN-1
|
IRE1 | Cell Cycle/Checkpoint |
IRE1α kinase-IN-1 是IRE1α 的选择性抑制剂(IC50为 77 nM),对 IRE1α 的选择性高于 IRE1β 亚型 100 倍。它抑制内质网诱导的 IRE1α 寡聚和自磷酸化,并抑制 IRE1α RNase 活性 (IC50=80 nM)。 | |||
T7483 |
6-Bromo-2-hydroxy-3-methoxybenzaldehyde
6-溴-2-羟基于-甲氧基苯甲醛,NSC95682 |
IRE1 | Cell Cycle/Checkpoint |
6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC-95682) 是一个 IRE-1α抑制剂,其 IC50值为 0.08 μM。 | |||
T21980 |
PD 198306
|
MEK | MAPK |
PD 198306 是一种具有抗痛觉过敏作用的 MAPK/ERK 激酶 (MEK) 选择性抑制剂。 PD 198306 可降低链脲佐菌素诱导的活性 ERK1 水平升高。 | |||
T8531 |
m-3M3FBS
2,4,6-三甲基-N-[3-(三氟甲基)苯基]苯磺酰胺 |
Apoptosis; Phospholipase | Apoptosis; Metabolism |
m-3M3FBS 是一种有效的磷脂酶C 激活剂,刺激人中性粒细胞产生超氧物,上调细胞内钙离子浓度,刺激多种细胞产生磷酸肌醇。它诱导单核细胞白血病细胞凋亡。 | |||
T0374L |
Sunitinib
苏尼替尼,舒尼替尼,SU 11248 |
Apoptosis; Mitophagy; VEGFR; FLT; IRE1; PDGFR; c-Kit; Autophagy | Angiogenesis; Apoptosis; Autophagy; Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors |
Sunitinib (SU 11248) 是一种多靶点受体酪氨酸激酶 (RTK) 抑制剂,可以抑制 VEGFR2 和 PDGFRβ (IC50=80/2 nM)。Sunitinib 具有抗肿瘤活性,可以用于治疗肾癌和胃肠道肿瘤。 | |||
T0374 |
Sunitinib Malate
苏尼替尼苹果酸盐,Sutent,SU 11248 (Malate),SU 11248,Sunitinib |
Apoptosis; Mitophagy; VEGFR; FLT; IRE1; PDGFR; c-Kit; Autophagy | Angiogenesis; Apoptosis; Autophagy; Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors |
Sunitinib Malate (Sunitinib) 是一种基于吲哚酮的酪氨酸激酶抑制剂,抑制 VEGFR2和 PDGFRβ的 IC50分别为80 nM 和 2 nM。它是 ATP 竞争性抑制剂,可通过抑制自身磷酸化和随后的 RNase 激活来有效抑制 Ire1α的磷酸化。 | |||
T0825 |
Ebselen
SPI-1005,PZ-51,依布硒,CCG-39161 |
Phosphatase; Virus Protease; Calcium Channel; COX; HIV Protease | Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome |
Ebselen (CCG-39161) 是一种谷胱甘肽过氧化物酶模拟物,是电压依赖性钙通道阻断剂。它抑制Mpro 和COVID-19病毒,是HIV-1衣壳 CTD 二聚化的抑制剂,具有抗炎、抗癌和抗氧化活性。 | |||
T75688 | 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol | ||
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol 是一种内源性代谢物,是细胞膜成分。 | |||
T77212 | L-α-lysophosphatidylinositol (Soy) (sodium) | ||
L-α-lysophosphatidylinositol Soy sodium 作为GPR55的内源性配体,是一种既属于内源性溶血磷脂也是内源性大麻素神经递质的化合物。 | |||
T31951 |
Glycerophosphoinositol choline
Plain |
||
Glycerophosphoinositol choline is the salt of choline and glycerophosphoinositol. | |||
T24094 |
Glycerophosphoinositol lysine
Distinctive gpi lysine,Gpi lysine |
||
Glycerophosphoinositol lysine has an anti-dandruff, anti-inflammatory, anti-aging activity. It significantly suppresses UVB - induced PGE secretion in NHEK keratinocytes. | |||
T30203 | Atrinositol | ||
Atrinositol improves energy homeostasis in a mouse model of pancreatic cancer. | |||
T41270 |
Phosphatidylinositols, soya, sodium salts
|
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T10877 |
CPDA
|
Phosphatase | Metabolism |
CPDA 是新型 SH2 domain-containing inositol phosphatase 2 抑制剂,能够作用于3T3-L1脂肪细胞,改善胰岛素抗性。 | |||
T60164 |
UNC7467
|
Others | Others |
UNC7467 是一种有效的IP6K 抑制剂,IP6K2、IP6K1 和 IP6K6 的IC50值分别为 4.9、8.9 和1320 nM。UNC7467 可降低肌醇焦磷酸盐的水平,而不会显着干扰其他肌醇磷酸盐的水平。UNC7467 可用于肥胖研究。 | |||
T36442L |
(Hyp³)-Bradykinin acetate
(Hyp³)-Bradykinin acetate (37642-65-2 Free base) |
Bradykinin Receptor | GPCR/G Protein |
(Hyp³)-Bradykinin acetate 是一种缓激肽 B2 受体激动剂,可刺激培养的人成纤维细胞中磷酸肌醇的产生。 | |||
T14037 |
3α-Aminocholestane
5α-Cholestan-3α-amine |
Phosphatase | Metabolism |
3α-Aminocholestane (5α-Cholestan-3α-amine) 是包含 SH2 结构域的肌醇-5'-磷酸酶 1 (SHIP1) 的有效抑制剂(IC50 : 2.5 μM),可用于研究和免疫相关的疾病。 | |||
T6347 | Ki16198 | LPA Receptor; LPL Receptor | GPCR/G Protein |
Ki16198 是一种可口服的 LPA 受体拮抗剂,是 Ki16425 的甲酯衍生物。它抑制 LPA1 和 LPA3 诱导的肌醇磷酸的Ki 值分别为 0.34 和 0.93 μM,可用于胰腺癌发生和转移的研究。 | |||
T9848 |
GSK2850163 (S enantiomer)
|
IRE1 | Cell Cycle/Checkpoint |
GSK2850163 (S enantiomer) 是 GSK2850163 的无活性对映体。GSK2850163 是一种新型的肌醇需求酶-1α (IRE1a) 抑制剂。 | |||
T22954 |
LY 456236 hydrochloride
MPMQ hydrochloride |
EGFR; GluR | Angiogenesis; JAK/STAT signaling; Neuroscience; Tyrosine Kinase/Adaptors |
LY 456236 hydrochloride (MPMQ hydrochloride) 是一种 mGlu1 受体拮抗剂,ic50值为143 nM。LY456236具有选择性、非竞争性和具有口服活性,对磷酸肌醇水解具有抑制作用, IC50值 为 0.145 μM。LY 456236 hydrochloride 对EGFR 具有抑制作用,其IC50 为 0.91 μM。 | |||
T14327 |
AS1949490
|
Phosphatase | Metabolism |
AS1949490 是选择性SHIP-2抑制剂,其IC50=620 nM。它能够通过上调L6肌管GLUT1基因激活葡萄糖代谢。 | |||
T14496 |
BAMB-4
ITPKA-IN-C14 |
Others | Others |
BAMB-4 (ITPKA-IN-C14) 是一种新型的膜渗透型ITPKA 抑制剂,在ADP-Glo 实验中的IC50值为37uM。 | |||
T11137 |
(E)-GABAB receptor antagonist 1
|
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
(E)-GABAB receptor antagonist 1 是 GABAB receptor antagonist 1 的反式结构。(E)-GABAB receptor antagonist 1 降低 GABA 诱导的 IP3 (三磷酸肌醇) 产生,IC50 为 37.9 μM。GABAB receptor antagonist 1是选择性的 GABAB (γ-氨基丁酸) 受体的负变构调节剂。 | |||
TP1896L1 |
Kisspeptin 234 acetate(1145998-81-7 free base)
|
GPR; Kisspeptin | Endocrinology/Hormones; GPCR/G Protein |
Kisspeptin 234 acetate(1145998-81-7 free base) 是Kisspeptin 受体 (KISS1, GPR54) 拮抗剂; 是Kisspeptin-10 类似物。它抑制 Kisspeptin-10 对磷酸肌醇 (IP) (IC50 = 7 nM) 的刺激和促性腺激素释放激素 (GnRH) 的释放。 | |||
T5148 |
Atosiban acetate
RW22164,Atosiban acetate (90779-69-4 free base),RWJ22164,醋酸阿托西班 |
Oxytocin Receptor; Vasopressin Receptor | Endocrinology/Hormones; GPCR/G Protein |
Atosiban acetate (RW22164) 是一种脱氨基催产素类似物,是一种九肽,也是竞争性的催产素受体拮抗剂。它是一种宫缩抑制剂,可用于自发早产的研究。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0421 |
i-Inositol
Inositol,myo-Inositol,肌醇,meso-Inositol |
Endogenous Metabolite | Metabolism |
i-Inositol (myo-Inositol) 是一种细胞内磷酸化合物,参与细胞信号传导,可能刺激肿瘤细胞分化。 | |||
T5915 |
D-chiro-Inositol
D-手性肌醇,D-(+)-CHIRO-INOSITOL |
Endogenous Metabolite | Metabolism |
D-chiro-Inositol (D-(+)-CHIRO-INOSITOL) 是肌醇差向异构体,存在于某些哺乳动物糖基磷脂酰肌醇蛋白锚和具有胰岛素样生物特性的肌醇磷脂聚糖中。它能够抑制高血糖,改善胰岛素抵抗。它用于多囊卵巢综合征和糖尿病的相关研究。 | |||
T8012 |
Scyllo-Inositol
Scyllitol,鲨肌醇 |
Beta Amyloid; Endogenous Metabolite | Metabolism; Neuroscience |
Scyllo-Inositol (Scyllitol) 是淀粉样抑制剂,能够抑制 α-突触核蛋白聚集。它在体外能够稳定非纤维状无毒形式的淀粉样蛋白-β 肽,逆转阿尔茨海默病小鼠模型的认知缺陷,抑制突触毒性和淀粉样斑块。 | |||
T2971 |
Phytic acid
Inositol hexaphosphate,inositol hexakisphosphate,inositol polyphosphate,myo-Inositol, hexakis(dihydrogen phosphate),植酸,Fytic Acid |
Xanthine Oxidase; Endogenous Metabolite | Metabolism |
Phytic acid (Fytic Acid) 是种子和谷粒的磷储存化合物。它被称为食品抑制剂,具有很强的螯合多价金属离子的能力,特别是钙,铁,锌和蛋白质残留物。它抑制超氧化物来源黄嘌呤氧化酶并具有抗氧化,抗炎以及神经保护作用。 | |||
T33632 |
Neo-inositol
J101.890F,Neo inositol,Inositol, neo-,Neoinositol |
||
Neo-Inositol is a group of chemically very stable small polar molecules with a variety of properties. It is one of the naturally occurring but rare inositol stereoisomers. | |||
T5075 |
Phytic acid potassium
植酸二钾盐,Inositol hexakisphosphate dipotassium salt,Phytic acid dipotassium salt,Fytic Acid dipotassium salt,Inositol polyphosphate dipotassium salt |
Others; Endogenous Metabolite | Metabolism; Others |
Phytic acid potassium (Inositol polyphosphate dipotassium salt) 是内源性代谢产物的一种。 | |||
T16527 |
Phytic acid dodecasodium salt hydrate
植酸十二钠盐,myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate,Inositol hexaphosphate dodecasodium salt hydrate |
Others; Xanthine Oxidase; Endogenous Metabolite | Metabolism; Others |
Phytic acid dodecasodium salt hydrate (myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate) 是种子和谷物的磷储存化合物。 Phytic acid dodecasodium salt hydrate 抑制酶促超氧化物源黄嘌呤氧化酶,IC50 为 6 mM,并具有抗氧化、神经保护和抗炎作用。 | |||
TMS0719 |
Sequoyitol
5-O-Methyl-Myo-Inositol,红杉醇,红杉醇,西曲依醇 |
Others | Others |
Sequoyitol (5-O-Methyl-Myo-Inositol) 来源于植物。它可以改善体内葡萄糖耐量,降低血糖,可用于糖尿病的研究。 | |||
T3823 |
D-Pinitol
Pinitol,Inzitol,D-(+)-Pinitol,D-松醇,Methylinositol,3-O-Methyl-D-chiro-inositol |
Others; Influenza Virus | Microbiology/Virology; Others |
D-Pinitol (Methylinositol) 是一种存在于几种植物中,如松科和豆科植物的天然产物,具有抗病毒、杀幼虫、降血糖活性和心血管系统保护作用。 | |||
T5584 |
Phytic acid sodium salt
Sodium phytate hydrate,玉米 |
Others | Others |
Phytic acid sodium salt (Sodium phytate hydrate) 源于豆类种子中,具有抗营养活性。它是 [PO4]3-储藏库,是其他肌醇磷酸酯和焦磷酸酯的前体,在植物中被植酸酶逐步水解。 | |||
T17143 |
Toyocamycin
丰加霉素,Vengicide |
Apoptosis; Others; IRE1; Antibiotic; Antifungal | Apoptosis; Cell Cycle/Checkpoint; Microbiology/Virology; Others |
Toyocamycin (Vengicide) 是放线菌类产生的腺苷类似物,为 X 盒结合蛋白 1 (XBP1) 抑制剂,抑制 IRE1α 诱导的 ATP 依赖性 XBP1 mRNA 的断裂,IC50值为 80 nM。它还诱导凋亡。 | |||
T73812 |
Phosphatidylinositol 4,5-bisphosphate
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Phosphatidylinositol 4,5-bisphosphate(L-alpha-Phosphatidylinositol-4,5-bisphosphate)为细胞膜磷脂成分,主要作为磷脂酶C(PLC)与磷酸肌醇3-激酶(PI3K)的底物,充当重要信使。 |