store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Atosiban acetate (RW22164) 是一种脱氨基催产素类似物,是一种九肽,也是竞争性的催产素受体拮抗剂。它是一种宫缩抑制剂,可用于自发早产的研究。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 248 | 现货 | ||
5 mg | ¥ 578 | 现货 | ||
10 mg | ¥ 828 | 现货 | ||
25 mg | ¥ 1,150 | 现货 | ||
50 mg | ¥ 1,490 | 现货 | ||
100 mg | ¥ 2,220 | 现货 | ||
500 mg | ¥ 5,290 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 963 | 现货 |
产品描述 | Atosiban acetate (RW22164) is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban acetate (RW22164) inhibits the oxytocin-mediated release of inositol trisphosphate from the myometrial cell membrane. As a result, there is reduced release of intracellular, stored calcium from the sarcoplasmic reticulum of myometrial cells, and reduced influx of Ca2+ from the extracellular space through voltage gated channels. In addition, Atosiban acetate (RW22164) suppresses oxytocin-mediated release of PGE and PGF from the decidua. In human pre-term labor, atosiban, at the recommended dosage, antagonizes uterine contractions and induces uterine quiescence. The onset of uterus relaxation following atosiban is rapid, uterine contractions being significantly reduced within 10 minutes to achieve stable uterine quiescence. |
别名 | RW22164, Atosiban acetate (90779-69-4 free base), RWJ22164, 醋酸阿托西班 |
分子量 | 1054.24 |
分子式 | C45H71N11O14S2 |
CAS No. | 914453-95-5 |
store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mM
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 0.9486 mL | 4.7428 mL | 9.4855 mL | 23.7138 mL |
5 mM | 0.1897 mL | 0.9486 mL | 1.8971 mL | 4.7428 mL | |
10 mM | 0.0949 mL | 0.4743 mL | 0.9486 mL | 2.3714 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Atosiban acetate 914453-95-5 Endocrinology/Hormones GPCR/G Protein Oxytocin Receptor Vasopressin Receptor RWJ 22164 nonapeptide RW22164 Preterm vasopressin RW 22164 Atosiban tocolytic desamino-oxytocin inhibit Ca2+ oxytocin maternal-fetal Atosiban Acetate 90779-69-4 free base Atosiban acetate (90779-69-4 free base) RWJ22164 Inhibitor RWJ-22164 醋酸阿托西班 90779-69-4 RW-22164 OXTR inhibitor