970
6
220
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T15465 |
HC-070
HC 070 |
TRP/TRPV Channel | Membrane transporter/Ion channel |
HC-070是一种 TRPC5和 TRPC4拮抗剂(IC50 = 9.3 nM 和46 nM)。 | |||
T4604 |
HC-056456
HC 056456,3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide |
Others | Others |
HC-056456 (3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide) 是一种有效但不完全选择性的 CatSper 通道阻断剂。它能够减慢 [Na+]i 上升(IC50:3 µM)。 | |||
T4680 |
HC-067047
HC067047 |
TRP/TRPV Channel | Membrane transporter/Ion channel |
HC-067047是一种有效的TRPV4选择性拮抗剂。HC067047可逆地抑制流经人,大鼠和小鼠TRPV4直系同源物的电流,IC50分别为 48 nM,133 nM 和 17 nM。 | |||
T6530 |
HC-030031
2-(1,3-二甲基-2,6-二氧代-2,3-二氢-1H-嘌呤-7(6H)-基)-N-(4-异丙基苯基)乙酰胺,HC030031,TOSLAB 829227 |
TRP/TRPV Channel | Membrane transporter/Ion channel |
HC-030031 (TOSLAB 829227) 是一种有效的TRPA1选择性抑制剂,拮抗福尔马林和AITC 诱发的钙流入,IC50分别为5.3±0.2和6.2±0.2μM。 | |||
T32048 |
HC 9016
9016-HC,9016 HC,HC-9016 |
||
HC 9016 is a biochemical. | |||
T27529 |
HC-3
HC 3 |
||
HC-3 inhibits ChoK by binding at the conserved hydrophobic groove on the C-terminal lobe. | |||
T16532 |
Pico145
HC-608 |
TRP/TRPV Channel | Membrane transporter/Ion channel |
Pico145 (HC-608) 是有效的瞬时受体电位通道蛋白 1/4/5 (TRPC1/TRPC4/TRPC5) 抑制剂,在细胞中,抑制 (-)-englerin A 活化TRPC4/TRPC5 通道的IC50分别为 0.349 和 1.3 nM。 | |||
T35774 |
HC Toxin
|
||
HC Toxin is a cell-permeable, reversible inhibitor of histone deacetylases (HDACs) (IC50 = 30 nM). Through its effects on HDACs, HC toxin has been shown to up-regulate the expression of 15-lipoxygenase-1 in colorectal cancer cells and induce fetal hemoglobin in human primary erythroid cells. HC Toxin is a cyclic tetrapeptide first isolated from H. carbonum (now C. carbonum), a pathogen of maize. | |||
T62380L |
20-HC-Me-Pyrrolidine FA
|
Others | Others |
20-HC-Me-Pyrrolidine FA 是一种有效的 Aster 蛋白抑制剂,对 Aster-A、Aster-B 和 Aster-C 具有抑制作用,抑制 Aster 蛋白结合和转移胆固醇。20-HC-Me-Pyrrolidine FA 可用于研究脂类代谢。 | |||
T0994 |
Ketotifen fumarate
HC 20511 fumarate,富马酸酮替芬 |
PDE; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience |
Ketotifen fumarate (HC 20511 fumarate) 是组胺 H1 受体和炎症介质释放的环七噻吩阻滞剂。 | |||
T4680L |
HC067047 Hydrochloride(883031-03-6 free base)
|
TRP/TRPV Channel | Membrane transporter/Ion channel |
HC067047 Hydrochloride(883031-03-6 free base) 是一种有效的选择性 TRPV4 拮抗剂。它可逆地抑制通过人类、大鼠和小鼠 TRPV4 直系同源物的电流,IC50 值分别为 486 nM、133nM 和 17 nM。 | |||
T71204 |
Apatinib HC
Rivoceranib HCl,YN-968D1 HCl |
||
Apatinib, also known as Rivoceranib and YN-968D1, is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. The free-base form is also known as Rivoceranib. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SR... | |||
T34934 |
Trichovirin I IB
Harzianin HC I |
||
Trichovirin I IB is a peptaibiotic, alpha-aminobutyric acid-rich secondary metabolite of fungi. | |||
T69470 |
HC103A
|
||
HC103A is an inhibitor of Mycobacterium tuberculosis DosRST signaling and persistence. | |||
T71727 |
HC102A
|
||
HC102A is an inhibitor of Mycobacterium tuberculosis DosRST signaling and persistence. | |||
T73336 |
Ketotifen
酮替芬,HC 20-511 |
||
Ketotifen (HC 20-511)为第二代口服活性非竞争性组胺1(H1)受体阻滞剂兼肥大细胞稳定剂,能体外阻断6-磷酸葡萄糖酸脱氢酶(6-PGD)。其对SARS-CoV-2及流感病毒(Influenza virus)展现出抗病毒活性,适用于自身免疫性脑脊髓炎(EAE)与哮喘发作预防研究。 | |||
T62380 |
20-HC-Me-Pyrrolidine
|
||
20-HC-Me-Pyrrolidine 是一种有效的 Aster 蛋白抑制剂,对 Aster-A、Aster-B 和 Aster-C 具有抑制作用, IC50 分别为 0.11 μM、0.06 μM 和 0.71 μM。20-HC-Me-Pyrrolidine 阻止 Aster 蛋白结合和转移胆固醇,抑制低密度脂蛋白 (LDL) 胆固醇向内质网 (ER) 的移动。 | |||
T33827 |
Oseltamivir carboxylate HCl
Oseltamivir carboxylate(HCI),GS4071 HC,Oseltamivir carboxylate HCI,Oseltamivir carboxylate hydrochloride,Ro 64-0802 hydrochloride |
||
Oseltamivir carboxylate is an active metabolite of oseltamivir phosphate (Tamiflu). | |||
T75370 |
CellTracker Blue CMF2HC Dye
|
||
CellTracker Blue CMF2HC Dye为蓝色荧光染料,适用于双通道核酸测序,激发光为蓝色和紫色(450-460 nm/400-405nm 或 415-450 nm/480-525nm)。此外,该染料亦应用于微生物抗生素敏感性快速测定。储存要求:避光。 | |||
T65815 |
H-Asp(OtBu)-OtBu HCl
|
Amino Acids and Derivatives | Metabolism |
H-Asp(OtBu)-OtBu HCl 是一种天冬氨酸衍生物,可能用于研究神经功能的比较和非酒精类肝炎类代谢性疾病。 | |||
T68114L |
Nardeterol HCl
Nardeterol HCl(73865-18-6 Free base) |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Nardeterol HCl 是一种 β肾上腺素能受体部分激动剂,可用于研究中枢神经系统。 | |||
T5162 |
MRT67307 HCl (1190378-57-4(free base))
盐酸MRT67307 |
IκB/IKK; AMPK; Autophagy | Autophagy; Chromatin/Epigenetic; NF-κB; PI3K/Akt/mTOR signaling |
MRT67307 HCl (1190378-57-4(free base)) 是 TBK1、MARK1-4、IKKε 和 NUAK1 的激酶抑制剂(IC50 分别为 19、27-52、160 和 230 nM)。 | |||
T10744L |
SEL120-34A HCl
|
CDK | Cell Cycle/Checkpoint |
SEL120-34A HCl 是一种可口服的,选择性的,ATP-竞争性的CDK8抑制剂,具有抗肿瘤活性,对 CDK8/CycC 和 CDK19/CycC 的IC50值分别为 4.4 nM 和 10.4 nM。 | |||
T21300 |
Trientine-2HCl
Triethylenetetramine,Trientine HCl,Trientine,盐酸三乙烯四胺,Triethylene tetramine,TETA,Trien |
Others | Others |
Trientine-2HCl (Trien) 是一种螯合剂,通过结合和去除体内的铜来治疗威尔逊氏病。曲恩汀还可用作肝豆状核变性中铜的螯合剂,环氧树脂的稳定剂,等电聚焦的两性电解质。 | |||
T9140 |
NAcM-OPT HCl(2089293-61-6 free base)
|
NEDD8 | Metabolism |
NAcM-OPT HCl(2089293-61-6 free base) 是一种可口服的 cullin neddylation 1 (DCN1) 抑制剂,靶向 N-Acetyl-UBE2M(E2 结合酶,UBC12)与 DCN1 的相互作用,IC50 为 79 nM。 | |||
T68067L |
Etilefrine pivalate HCl
Etilefrine pivalate HCl(100696-30-8 Free base) |
||
Etilefrine pivalate HCl 是一种具有口服活性的化合物,可用于治疗偏头痛。 | |||
T8738 |
LUN42518 HCl 47142-51-8(free base)
|
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
LUN42518 HCl 47142-51-8(free base) 是酚妥拉明的类似物。酚妥拉明是一种非选择性的α-肾上腺素能拮抗剂。 | |||
T22364 |
Methyl 4-aminobutyrate HCl
4-氨基丁酸甲酯盐酸盐,Methyl 4-aminobutyrate hydrochloride,GABA methyl ester |
Others | Others |
Methyl 4-aminobutyrate HCl (GABA methyl ester) 是一种由氨基丁酸和甲醇缩合而成的甲酯化合物。 | |||
T10276L |
AKT Kinase Inhibitor HCl
AKT Kinase Inhibitor HCl(842148-40-7 Free base) |
Akt | Cytoskeletal Signaling; PI3K/Akt/mTOR signaling |
AKT Kinase Inhibitor HCl 是一种 Akt 抑制剂,具有抗肿瘤活性。 | |||
T21319L |
Gimatecan HCl
ST1481 HCL,Gimatecan HCl(292618-32-7 Free base) |
Topoisomerase | DNA Damage/DNA Repair |
Gimatecan HCl (ST1481 HCL) 是一种有效的拓扑异构酶 I (topoisomerase I) 抑制剂。Gimatecan HCl 是一种具有口服活性的喜树碱类似物。具有抗肿瘤活性。 | |||
T77676 |
(Z)-Metanicotine 2HCl
(Z)-Metanicotine 2HCl(1129-68-6 Free base) |
Others | Others |
(Z)-Metanicotine 2HCl 具有镇痛活性,可用于治疗中枢系统疾病。 | |||
TP1663L |
CysHHC10 acetate
CysHHC10 acetate(1408311-03-4 free base) |
Antibacterial | Microbiology/Virology |
CysHHC10 acetate 对革兰氏阳性菌和革兰氏阴性菌均具有抗菌活性,对大肠杆菌、铜绿假单胞菌、金黄色葡萄球菌和表皮葡萄球菌的 MIC 分别为 10.1、20.2、2.5 和 1.3 mM。 | |||
T26627L |
Anatibant 2HCl
Anatibant 2HCl(209733-45-9 Free base) |
Bradykinin Receptor | GPCR/G Protein |
Anatibant 2HCl 是一种小分子缓激肽B2受体拮抗剂,可用于治疗神经系统疾病,可能用于研究脑损伤。 | |||
T28686 |
SB-237376 HCl
SB-237376 hydrochloride |
Calcium Channel; Sodium Channel | Membrane transporter/Ion channel; Metabolism |
SB-237376 HCl (SB-237376 hydrochloride) 是一种钙和钾通道拮抗剂,可用于治疗心律失常。 | |||
T4087 |
S 38093 HCl
|
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
S 38093 HCl 是一种新型的脑渗透性 H3 受体拮抗剂/反向激动剂。 | |||
T15760L |
Lintopride HCl(107429-63-0 Free base)
|
||
T11538 |
Hck-IN-1
|
HIV Protease; Src; Hck | Angiogenesis; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors |
Hck-IN-1 是二苯基吡唑啉化合物,选择性的 Nef 依赖性 Hck 抑制剂。它是广泛的 HIV-1 Nef 直接拮抗剂,对于野生型 HIV-1 复制的IC50为 100-300 nM。它结合口袋残基 Asn126,具有抗逆转录病毒活性。 | |||
T83974 |
OPC18750 HCl
|
PDE | Metabolism |
OPC18750 HCl 是一种潜在的磷酸二酯酶抑制剂,具有正肌力作用,可用于研究哮喘、癌症、糖尿病和精神疾病。 | |||
T19958 |
2-Iminothiolane HCl
2-Iminothiolane,2-亚氨基硫烷盐酸盐,Traut's reagent,Trauts reagent,2-IT |
Others | Others |
2-Iminothiolane HCl (Trauts reagent) 可用于将巯基引入衍生自天冬酰胺连接聚糖的寡糖中。 | |||
T68037L |
CBS-1114 HCl
N-Phenylbenzamidrazone hydrochloride,cbs-1114 HCl(46721-85-1 Free base) |
Lipoxygenase | Metabolism |
CBS-1114 HCl (N-Phenylbenzamidrazone hydrochloride) 是一种5-脂氧合酶抑制剂,是一种良好眼睛渗透型号的抗炎化合物。CBS-1114 HCl 可以保持和改善心脏功能,减轻心功能障碍,以及减少患有心血管疾病的受试者的心外膜脂肪组织和/或心包脂肪组织。 | |||
T6139L |
A-674563 2HCl(552325-73-2(fb-2hcl))
|
ERK; Akt; PKA; CDK; PKC | Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors |
A-674563 2HCl(552325-73-2(fb-2hcl)) 是一种 Akt1 抑制剂,Ki 为 11 nM,对 PKA 有效,对 Akt1 的选择性比 PKC 高 30 倍以上。 | |||
T77673 |
7-FluorotryptaMine HCl
|
GPR; Arrestin | Endocrinology/Hormones; GPCR/G Protein |
7-FluorotryptaMine HCl 是一种有效的芳香单胺 GPRC5A 激动剂,可诱导 GPRC5A 介导的 β-arrestin 募集。7-FluorotryptaMine HCl 可用于研究与免疫和癌症相关的信号通路。 | |||
T5398 |
BMS 599626 2HCl (873837-23-1(HCl))
AC480 dihydrochloride |
HER | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
BMS 599626 2HCl (873837-23-1(HCl)) (AC480 dihydrochloride) 是 HER1 和 HER2 的选择性抑制剂(IC50:20 nM 和 30 nM),对 HER4 的效力降低约 8 倍,对 Lck、VEGFR2、c-Kit、MET 等的效力降低 100 倍以上。 | |||
T2610L |
BMS-599626 2HCL(714971-09-2 Free base)
BMS 599626 dihydrochloride,BMS-599626 2HCL(714971-09-2 Free base),AC480 2HCl |
HER | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
BMS-599626 2HCL (AC480 2HCl) 是BMS-599626 衍生物。BMS-599626 是一种可口服且具有选择性的 HER1 和 HER2 双重抑制剂, IC50 分别为 20 和 30 nM。BMS-599626 抑制肿瘤细胞增殖,并有可能增加肿瘤对放疗的反应。 | |||
T50034 |
1-{1H-pyrrolo[2,3-d]pyrimidin-4-yl}piperazine 2HCl
|
Others | Others |
1-{1H-pyrrolo[2,3-d]pyrimidin-4-yl}piperazine dihydrochloride (1-PPZ-DHC)是一种用作分子结构单元的化合物。它是天然产物哌嗪的类似物,具有广泛的生物活性,包括抗炎、抗肿瘤和抗菌活性,同时还被研究用于治疗神经系统疾病,如阿尔茨海默氏症和帕金森氏症。 | |||
T50047 |
1-(3,4-Dihydroxyphenyl)-2-(dimethylamino)ethanone HCl
|
Others | Others |
1-(3,4-dihydroxyphenyl)-2-(dimethylamino)ethan-1-one hydrochloride 是一种胆碱能制剂,抑制胆碱代谢,从而导致大脑中乙酰胆碱水平的增加,进而增强认知功能和记忆。 | |||
T50092 |
1-(7-carbamimidamidoheptyl)guanidine 2HCl
1-(7-carbamimidamidoheptyl)guanidine dihydrochloride,1,1'-(Heptane-1,7-diyl)diguanidine 2HCl |
Others | Others |
1,1'-(Heptane-1,7-diyl)diguanidine dihydrochloride 是糖原合成酶激酶-3(GSK-3)的有效性和选择性小分子抑制剂,用于干细胞分化、肿瘤和神经退行性疾病的研究。 | |||
T6158 |
LDN-193189 HCl
LDN193189 Hydrochloride |
ALK | Angiogenesis; Tyrosine Kinase/Adaptors |
LDN-193189 HCl (LDN193189 Hydrochloride) 是一种选择性 BMP I 型受体激酶抑制剂。 | |||
T50063 |
(2-methyl-2,3-dihydro-1H-inden-2-yl)methanamine HCl
|
Others | Others |
(2-methyl-2,3-dihydro-1H-inden-2-yl)methanamine hydrochloride 是一种环状胺,在结构上与安非他命有关,并已被证明对中枢神经系统具有显著影响。 | |||
T39284 |
EST73502 HCl
|
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
EST73502 是 μ-阿片受体激动剂 (Ki = 64 nM) 激动剂和 σ1 受体拮抗剂 (Ki = 118 nM)。 EST73502 显示出镇痛活性。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4866 |
H-Trp-NH2.HCl
L-Tryptophanamide hydrochloride,L-色氨酰胺盐酸盐,(2S)-2-amino-3-(1H-indol-3-yl)propanamide hydrochloride |
Others; Endogenous Metabolite | Metabolism; Others |
H-Trp-NH2.HCl ((2S)-2-amino-3-(1H-indol-3-yl)propanamide hydrochloride) 是一种内源性代谢产物,已在多种生物体液中检测到,如尿液和血液。 | |||
T3938 |
H-HomoArg-OH.HCl
NSC 145416,L-Homoarginine hydrochloride,L-高精氨酸盐酸盐,L(+)-Homoarginine hydrochloride |
Endogenous Metabolite; Phosphorylase | Metabolism |
H-HomoArg-OH.HCl (L-Homoarginine hydrochloride) 是内源性代谢产物的一种。 | |||
T64911 |
Blasticidin S HCl
|
Antibiotic | Microbiology/Virology |
Blasticidin S HCl 是从 Streptomyces griseochromogenes 中分离的肽基核苷类抗生素 (antibiotic),主要通过干扰核糖体中肽键的形成从而抑制原核细胞和真核细胞蛋白的合成。 | |||
TN4698 |
Ohchinin acetate
|
Others | Others |
Ohchinin acetate is a natural product from Melia azedarach. | |||
TN4882 |
Quinine HCl
奎宁树 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Quinine HCl produces alpha-adrenergic blockade. Quinine modifies catecholamine- and calcium-induced myocardial contractile force responses. | |||
TN4699 | Ohchinin | Others | Others |
Ohchinin exhibits potent inhibitory activities with 26 - 66% reduction of melanin content at 100 μm concentration with almost no or low toxicity to the B16 melanoma cells (70 - 99% cell viability at 100 μm). |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02342 |
Collagenase Protein, Hypoderma lineatum, Recombinant (His & Myc)
Collagenase,HC,Hypodermin C |
Hypoderma lineatum | E. coli |
This enzyme is a serine protease capable of degrading the native triple helix of collagen. Also cleaves the B chain of insulin at the 15-Leu-|-Try-16 and 22-Arg-|-Gly-23 bonds. Hydrolyzes casein, but not Px-Pro-Leu-Gly-Pro-DArg, BzArgNHPh, AcTyrNHPh, 2-naphthyl phosphate, 2-naphthyl butyrate, 2-naphthyl caprylate, 2-naphthyl myristate, L-leucine 2-2-naphthylamide, L-valine 2-naphthylamide, L-cysteine 2-naphthylamide or L-glutarylphenylalanine 2-naphthylamide. | |||
TMPY-01304 |
YKL-40/CHI3L1 Protein, Human, Recombinant (His)
YKL-40,CGP-39,HC-gp39,GP39,DKFZp686N19119,HC |
Human | HEK293 Cells |
YKL-40/CHI3L1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is A0A024R969. | |||
TMPY-02104 |
MCP-2 Protein, Mouse, Recombinant (His & NusA)
MCP-2,Mcp2,chemokine (C-C motif) ligand 8,HC14,1810... |
Mouse | E. coli |
MCP-2 Protein, Mouse, Recombinant (His & NusA) is expressed in E. coli expression system with His and NusA tag. The predicted molecular weight is 66 kDa and the accession number is Q9Z121. | |||
TMPY-00118 |
MCP-1/CCL2 Protein, Human, Recombinant (His)
SCYA2,HC11,MCAF,HSMCR30,MCP-1,MCP1,GDCF-2,SMC-CF,ch... |
Human | P. pastoris (Yeast) |
MCP-1/CCL2 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 10.1 kDa and the accession number is P13500. | |||
TMPY-00296 |
Hepatitis C virus (HCV) (serotype 1c,isolate HC-G9) E2 Protein (His)
HCV-1a E2 |
HCV | HEK293 Cells |
Hepatitis C virus (HCV) (serotype 1c,isolate HC-G9) E2 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.2 kDa and the accession number is BAA03581.1. | |||
TMPY-05166 |
Hepatitis C virus (HCV) (serotype 1b, isolate HC-J4) Envelope/E2 Protein (His)
HCV-1a E2 |
HCV | HEK293 Cells |
Hepatitis C virus (HCV) (serotype 1b, isolate HC-J4) Envelope/E2 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.4 kDa and the accession number is AAC15723.1. | |||
TMPY-04135 |
Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His)
HCV-E1 |
HCV | HEK293 Cells |
Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.7 kDa and the accession number is AAC15725.1. | |||
TMPY-04680 |
MCP-2 Protein, Human, Recombinant (His)
SCYA10,MCP2,chemokine (C-C motif) ligand 8,HC14,MCP... |
Human | P. pastoris (Yeast) |
MCP-2 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 10.3 kDa and the accession number is P80075. | |||
TMPY-04078 |
PSMA3 Protein, Human, Recombinant (His)
HC8,PSC3,proteasome (prosome, macropain) subunit, α... |
Human | E. coli |
PSMA3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30.7 kDa and the accession number is AAH29402.1. | |||
TMPJ-00234 |
AMBP Protein, Human, Recombinant (His)
α-1-Microglobulin,Uronic-Acid-Rich Protein,Inter-α-Trypsin I... |
Human | HEK293 Cells |
Protein AMBP belongs to the calycin superfamily and Lipocalin family. AMBP can be cleaved into three chains: α-1-microglobulin, inter-α-trypsin inhibitor light chain and trypstatin. AMBP is expressed by the liver and secreted in plasma. α-1-microglobulin occurs in many physiological fluids including the plasma, urine, and cerebrospinal fluid. Inter-α-trypsin inhibitor is present in the plasma and urine. α-1-microglobulin occurs as a monomer and also in complexes with IgA and albumin, Inter-α-try... | |||
TMPY-01887 |
MCP-2 Protein, Human, Recombinant (SUMO)
HC14,MCP-2,chemokine (C-C motif) ligand 8,SCYA10,MC... |
Human | E. coli |
MCP-2 Protein, Human, Recombinant (SUMO) is expressed in E. coli expression system with SUMO tag. The predicted molecular weight is 21.7 kDa and the accession number is P80075-1. | |||
TMPY-05653 |
MCP-1/CCL2 Protein, Mouse, Recombinant (His), Biotinylated
MCP-1,chemokine (C-C motif) ligand 2,HC11,SMC-CF,MC... |
Mouse | Baculovirus Insect Cells |
MCP-1/CCL2 Protein, Mouse, Recombinant (His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is P10148. | |||
TMPY-00606 |
MCP-1/CCL2 Protein, Mouse, Recombinant (His)
AI323594,HC11,Sigje,MCP-1,MCAF,Scya2,JE,SMC-CF,MCP1... |
Mouse | Baculovirus Insect Cells |
MCP-1/CCL2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is P10148. | |||
TMPY-00917 |
Serpin D1 Protein, Human, Recombinant (His)
serpin peptidase inhibitor, clade D (heparin cofactor), memb... |
Human | HEK293 Cells |
Serpin D1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.4 kDa and the accession number is P05546. | |||
TMPK-00011 |
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated
SMC-CF,HC11,MCAF,MCP1,MCP-1,HSMCR30,C-C motif chemo... |
Human | HEK293 Cells |
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 11.5 kDa and the accession number is P13500. | |||
TMPK-00010 |
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi)
MCP-1,MCAF,GDCF-2,SMC-CF,C-C motif chemokine 2,SCYA2,HC<... |
Human | HEK293 Cells |
MCP-1/CCL2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 11.5 kDa and the accession number is P13500. | |||
TMPK-00916 |
MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His)
MCP-1,MCP1,SCYA2,GDCF-2,MCAF,CCL2,SMC-CF,HC11,HSMCR... |
Cynomolgus | HEK293 Cells |
MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 9.79 kDa and the accession number is P61274. | |||
TMPY-00646 |
CCL4 Protein, Human, Recombinant (His)
SCYA2,G-26,MIP-1-β,LAG-1,MIP1B,AT744.1,SCYA4,MIP-1-beta,chem... |
Human | P. pastoris (Yeast) |
CCL4 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.2 kDa and the accession number is P13236. | |||
TMPJ-00010 |
CCL8 Protein, Human, Recombinant
Monocyte Chemoattractant Protein 2,C-C Motif Chemokine 8,MCP... |
Human | E. coli |
CCL8 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12 KDa and the accession number is P80075. | |||
TMPJ-00591 |
CCL8 Protein, Human, Recombinant (His)
SCYA8,MCP-2,Monocyte Chemotactic Protein 2,C-C Motif Chemoki... |
Human | HEK293 Cells |
CCL8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 13 KDa and the accession number is AAI26243.1. | |||
TMPJ-00009 |
CCL2 Protein, Human, Recombinant
C-C motif chemokine 2,MCAF,CCL2,MCP-1,Monocyte chemotactic p... |
Human | E. coli |
The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2)), is a small cytokine that belongs to the CC chemokine family responsible for monocyte attraction. Its cognate receptor, CCR2, play a critical role in regulating nociceptive processes during neuropathic pain. Both CCL2 and CCR2 are implicated in induction of autoimmunity. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation... | |||
TMPY-00811 |
Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein
Human cytωlovirus (HCMV) Glycoprotein B/gB |
CMV | HEK293 Cells |
Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 92 kDa and the accession number is P13201. | |||
TMPY-05677 |
Human coronavirus (HCoV-OC43) Spike Protein (S1+S2 ECD, His)
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HCoV-OC43 | Baculovirus Insect Cells |
Human coronavirus (HCoV-OC43) Spike Protein (S1+S2 ECD, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 145.1 kDa and the accession number is A0A2P1ZWW8. | |||
TMPY-01201 |
Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (His)
Human cytωlovirus (HCMV) Glycoprotein B/gB |
CMV | HEK293 Cells |
Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 93.2 kDa and the accession number is P13201. | |||
TMPY-05750 |
Human coronavirus (HCoV-OC43) Spike S1 Protein (His)
|
HCoV-OC43 | HEK293 Cells |
Human coronavirus (HCoV-OC43) Spike S1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 89.02 kDa and the accession number is A0A2P1ZWW8. | |||
TMPY-05675 |
Human coronavirus (HCoV-229E) Spike Protein (S1+S2 ECD, His)
|
HCoV-229E | Baculovirus Insect Cells |
Human coronavirus (HCoV-229E) Spike Protein (S1+S2 ECD, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 122.1 kDa and the accession number is A0A1L7B942. | |||
TMPY-05676 |
Human coronavirus HKU1 (isolate N5) (HCoV-HKU1) Spike Protein (S1+S2 ECD, His)
|
HCoV-HKU1 | Baculovirus Insect Cells |
Human coronavirus HKU1 (isolate N5) (HCoV-HKU1) Spike Protein (S1+S2 ECD, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 144.4 kDa and the accession number is Q0ZME7.1. | |||
TMPY-05773 |
Human coronavirus (HCoV-HKU1) Nucleocapsid Protein (His)
|
HCoV-HKU1 | E. coli |
Human coronavirus (HCoV-HKU1) Nucleocapsid Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 43.21 kDa and the accession number is Q19U25. | |||
TMPY-05674 |
Human coronavirus (HCoV-NL63) Spike Protein (S1+S2 ECD, His)
|
HCoV-NL63 | Baculovirus Insect Cells |
Human coronavirus (HCoV-NL63) Spike Protein (S1+S2 ECD, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 142.4 kDa and the accession number is A0A1L2YVI8. | |||
TMPY-02429 |
Human coronavirus HKU1 (isolate N1) (HCoV-HKU1) Spike S1 Protein (His)
|
HCoV-HKU1 | HEK293 Cells |
Human coronavirus HKU1 (isolate N1) (HCoV-HKU1) Spike S1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.8 kDa and the accession number is Q5MQD0. | |||
TMPY-06013 |
Human coronavirus (HCoV-OC43) Spike S2 Protein (His)
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HCoV-OC43 | Baculovirus Insect Cells |
Human coronavirus (HCoV-OC43) Spike S2 Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 60.7 kDa and the accession number is A0A2P1ZWW8. | |||
TMPY-05766 |
Human coronavirus (HCoV-NL63) Nucleocapsid Protein (His)
|
HCoV-NL63 | E. coli |
Human coronavirus (HCoV-NL63) Nucleocapsid Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 43.21 kDa and the accession number is H9EJA4. | |||
TMPY-05671 |
Human coronavirus (HCoV-229E) Spike S1 Protein (His)
|
HCoV-229E | HEK293 Cells |
Human coronavirus (HCoV-229E) Spike S1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.3 kDa and the accession number is A0A1L7B942. | |||
TMPY-05775 |
Human coronavirus (HCoV-229E) Nucleocapsid Protein (His)
|
HCoV-229E | E. coli |
Human coronavirus (HCoV-229E) Nucleocapsid Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 44.43 kDa and the accession number is P15130. | |||
TMPY-05774 |
Human coronavirus (HCoV-OC43) Nucleocapsid Protein (His)
|
HCoV-OC43 | E. coli |
Human coronavirus (HCoV-OC43) Nucleocapsid Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 50.43 kDa and the accession number is YP_009555245.1. | |||
TMPY-05670 |
Human coronavirus (HCoV-NL63) Spike S1 Protein (His)
|
HCoV-NL63 | HEK293 Cells |
Human coronavirus (HCoV-NL63) Spike S1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.8 kDa and the accession number is A0A1L2YVI8. | |||
TMPK-01400 |
HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated
NS,KRAS1,RALD,K-RAS2A,K-RAS2B,K-RAS4A,MHC,RASK2,KRA... |
Human | E. coli |
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. | |||
TMPK-01407 |
HLA-A*02:01&B2M&KRAS WT (KLVVVGAGGV) Monomer Protein, Human, MHC (His & Avi), Biotinylated
KRAS2,RALD,C-K-RAS,NS3,MHC,CFC2,KRAS,KI-RAS,K-RAS4B... |
Human | E. coli |
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. | |||
TMPK-01422 |
Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi)
Peptide Ready,MHC,HLA-A*02:01 |
Human | HEK293 Cells |
Peptide Ready HLA-A*02:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner. | |||
TMPK-01536 |
HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
NS3,MHC,KRAS,RALD,CFC2,K-RAS2B,GTPase Kras,K-Ras 2,... |
Human | HEK293 Cells |
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail. | |||
TMPK-01475 |
HLA-A*24:02&B2M&GP100 Intron 4 (VYFFLPDHL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
HLA-A*24:02,Intron 4,gp100,GP100 Intron 4,Glycoprotein 100,M... |
Human | HEK293 Cells |
Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is involved in melanosome maturation. The Human HLA-A*0201 gp100 (YLEPGPVTA) complex Protein is a complex of HLA-A*0201 of the MHC Class I, B2M and YLEPGPVTA peptide of the gp100. | |||
TMPK-01459 |
HLA-A*02:01&B2M&MAGE-A4 or MAGE-A8 (KVLEHVVRV) Monomer Protein, Human, MHC (His & Avi), Biotinylated
MAGE-A4 or MAGE-A8,MAGE-A8,MAGE-A4 |
Human | HEK293 Cells |
MAGE-A4 and MAGE-A8 are type I membes of the melanoma associated antigen (MAGE) family. The MAGE family is a large, highly conserved group of proteins that share a common MAGE homology domain. Both MAGE-A4 and MAGE-A8 antigen-presenting peptides can be presented by HLA-A*02:01. | |||
TMPK-01464 |
HLA-A*11:01&B2M&KRAS G12R (VVVGARGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
C-K-RAS,K-RAS4A,GTPase Kras,K-RAS2A,NS,K-RAS2B,MHC,... |
Human | HEK293 Cells |
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail. | |||
TMPK-01414 |
Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein, Mouse, MHC (His & Avi)
Qa-1b,Qdm,MHC,H2-T23 |
Mouse | HEK293 Cells |
Qa-1b binds a peptide (AMAPRTLLL), referred to as Qdm (for Qa-1 determinant modifier), derived from the signal sequence of murine class Ia molecules. This peptide binds with high affinity and accounts for almost all of the peptides associated with this molecule. Human histocompatibility leukocyte antigen (HLA)-E, a homologue of Qa-1b, binds similar peptides derived from human class Ia molecules and interacts with CD94/NKG2 receptors on natural killer cells. | |||
TMPK-01502 |
HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
PSMB9,LMP2,Macropain chain 7,MHC,Proteasome chain 7... |
Human | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma... | |||
TMPK-01546 |
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi)
MHC,CT6.1,CTAG1,MY-ESO-1,ESO1CTAG,CTAG1B,NY-ESO-1,L... |
Human | HEK293 Cells |
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy. | |||
TMPK-01471 |
HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi), FITC-Labeled
CFC2,KRAS,K-RAS4B,MHC,K-RAS2B,KRAS1,NS3,K-RAS2A,NS,... |
Human | HEK293 Cells |
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. | |||
TMPK-01522 |
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi)
RMF,WT33,WIT-2,MHC,WAGR,AWT1,GUD,WT1,NPHS4GUD |
Human & Mouse | HEK293 Cells |
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of the MHC Class I, B2M and RMFPNAPYL peptide of the WT-1. | |||
TMPK-01535 |
Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)
Macropain chain 7,LMP2,Proteasome chain 7,RING12,PSMB9,M... |
Human & Mouse | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma... | |||
TMPK-01453 |
HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
RASK2,CFC2,K-Ras 2,NS3,GTPase Kras,KRAS1,K-RAS4B,K-RAS2B,M |
Human | HEK293 Cells |
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail. | |||
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