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Search Results for " 转化生长因子 "

Targets Recommended: ALK TGF-beta/Smad

26

抑制剂 & 化合物

6

天然产物

8

化合物库

5

TargetMol 试剂盒

30

重组蛋白

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Cat. No.	Product Name
L4100	TGF-β/Smad靶点化合物库		184 compounds
	184 个 TGF-β/Smad 靶点相关的小分子化合物的特有集合，用于高通量、高内涵筛选；
L2100	抗癌化合物库		7234 compounds
	7234 种肿瘤相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L1100	蛋白酶抑制剂库		343 compounds
	343 种已知的小分子蛋白酶抑制剂的特有集合，可用于高通量筛选和高内涵筛选；
L2110	抗癌上市药物库		1779 compounds
	1779 个具有抗癌活性小分子的独特集合，所有化合物都经过了严格的临床前研究和临床试验，由FDA、EMA 或NMPA 批准上市，可用于高通量、高内涵筛选。
L1610	FDA 上市激酶抑制剂库		263 compounds
	263种靶向激酶的上市药物集合，用于特定靶向激酶，可用于高通量筛选和高内涵筛选；
L2120	抗癌临床化合物库		2545 compounds
	2545 个具有抗癌活性小分子的独特集合，可用于高通量高内涵筛选。
L2550	谷氨酰胺代谢化合物库		565 compounds
	565 种谷氨酰胺代谢相关的分子，可以用于高通量和高内涵筛选；
L7110	抗高血压化合物库		678 compounds
	678 种高血压相关的小分子，用于高通量和高内涵筛选；

化合物库

TGF-β/Smad靶点化合物库

Cat.No: L4100

Compounds: 184

抗癌化合物库

Cat.No: L2100

Compounds: 7234

蛋白酶抑制剂库

Cat.No: L1100

Compounds: 343

抗癌上市药物库

Cat.No: L2110

Compounds: 1779

FDA 上市激酶抑制剂库

Cat.No: L1610

Compounds: 263

抗癌临床化合物库

Cat.No: L2120

Compounds: 2545

谷氨酰胺代谢化合物库

Cat.No: L2550

Compounds: 565

抗高血压化合物库

Cat.No: L7110

Compounds: 678

Cat. No.	Product Name	Form	Specificity Of Inhibition
CL0058	EGFR inhibitor kit EGFR inhibitor kit
CL0080	TGFβ signaling pathway inhibitor/activator kit TGFβ signaling pathway inhibitor/activator kit
CL0089	c-Met/HGFR inhibitor kit c-Met/HGFR inhibitor kit
CL0112	PKC inhibitor kit PKC inhibitor kit
CL0139	ROS inhibitor kit ROS inhibitor kit

TargetMol 试剂盒

EGFR inhibitor kit

Cat.No: CL0058

TGFβ signaling pathway inhibitor/activator kit

Cat.No: CL0080

c-Met/HGFR inhibitor kit

Cat.No: CL0089

PKC inhibitor kit

Cat.No: CL0112

ROS inhibitor kit

Cat.No: CL0139

Cat. No.	Product Name	Target	Signaling Pathways
T1763	SB 525334 SB525334	ALK; TGF-beta/Smad	Angiogenesis; Stem Cells; Tyrosine Kinase/Adaptors
	SB525334是转化生长因子β1受体 (ALK5) 选择性抑制剂，IC50=14.3 nM。
T4662	SJ000291942	TGF-beta/Smad	Stem Cells
	SJ000291942 是一种经典骨形态发生蛋白 (BMP) 信号传导途径的激活剂。其中 BMP 是一种转化生长因子 β 分泌信号分子家族的成员。
T13604	CDDO-dhTFEA	Others; NF-κB; Nrf2	Immunology/Inflammation; NF-κB; Others
	CDDO-dhTFEA 是合成的齐墩果烷三萜化合物，可有效激活Nrf2并抑制促炎转录因子NF-κB。它可以恢复高血压 (MAP)，提高 Nrf2 及其靶基因的表达，抑制 NF-κB 的活化和转化生长因子-β 途径，并减少慢性肾病 (CKD) 大鼠的肾小球硬化，间质纤维化和炎症。
T76866	Icrucumab LY 3012212,IMC-18F1	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Icrucumab ( IMC-18F1) 是一种人源化靶向血管内皮生长因子受体-1 的 IgG1 单克隆抗体。Icrucumab具有抗肿瘤活性，Icrucumab 具有研究转移性结肠癌。
T11052L	Disitertide acetate P144 acetate,Disitertide acetate(272105-42-7 Free base)	TGF-beta/Smad	Stem Cells
	Disitertide acetate (P144 acetate) 是转化生长因子 TGFβ1 的多肽抑制剂，特异性的阻断其与受体间的相互作用。Disitertide acetate 也是PI3K 的抑制剂和凋亡 (apoptosis) 诱导剂。
T62483	CJJ300	TGF-beta/Smad	Stem Cells
	CJJ300 是一种转化生长因子-β（TGF-β）抑制剂（IC50 : 5.3 μM）。CJJ300 通过破坏 TGF-β-TβR-I-TβR-II 信号传导复合物的形成来抑制 TGF-β 信号传导。CJJ300 可抑制细胞迁移。
T76681	Fresolimumab GC1008	TGF-beta/Smad	Stem Cells
	Fresolimumab (GC1008) 是一种具有特异性的人抗转化生长因子 β单克隆抗体，可与人 TGFβ1、TGFβ2 和 TGFβ3 的活性形式结合，可用于研究成人局灶节段性肾小球硬化和癌症。
T4013	SGC2085 HCl	Histone Methyltransferase	Chromatin/Epigenetic
	SGC2085 HCl 是一种有效的选择性辅激活剂相关的精氨酸甲基转移酶 1 (CARM1) 抑制剂，IC50 为 50 nM，选择性比其他 PRMT 高出数倍。 CARM1 是结直肠癌中 Wnt/β-catenin 转录和肿瘤转化的重要正调节因子，也是雌激素刺激的乳腺癌生长的关键因素，其耗竭导致体内髓性白血病细胞增殖减少。
T19710	Ciglitazone Ciglitazona,U 63287,ADD3878,ADD-3878,U-63287,ADD 3878	Apoptosis; p38 MAPK; PPAR	Apoptosis; DNA Damage/DNA Repair; MAPK; Metabolism
	Ciglitazone (ADD 3878) 是一种强效和选择性的PPARγ激动剂(EC50：3μM)和口服降糖药。Ciglitazone 抑制th17细胞的增殖和分化，降低胰岛素水平、血管内皮生长因子的产生和血压，诱导胃癌细胞的细胞周期停止。Ciglitazone 能诱导负鼠肾上皮细胞的凋亡，激活p38 MAPK 和凋亡诱导因子(AIF)的核转位。 Ciglitazone 在肥胖症和高血糖症的动物模型中表现出降血糖活性。
T60596	TGFβ-IN-1
	TGFβ-IN-1一种通过抑制转化生长因子β信号通路的抗肿瘤生长和转移剂。
T75717	Disitertide diammonium
	Disitertide (P144) diammonium 是转化生长因子TGFβ1的多肽抑制剂，特异性的阻断其与受体间的相互作用。Disitertide diammonium 也是PI3K 的抑制剂和凋亡 (apoptosis) 诱导剂。
T62277	PPARδ agonist 8
	Pparδ agonist 8 是一种 Pparδ 的有效激动剂。其中过氧化物酶体增殖物激活受体 (PPAR) 属于核内受体转录因子超家族，在体内代谢稳态、炎症、细胞生长和分化的调节中具有关键作用。Pparδ agonist 8 具有潜力进行非酒精性脂肪肝 (NAFLD) 的研究。
T80588	Bintrafusp alfa M7824,MSB0011359C
	Bintrafusp alfa (M 7824) 是高端双功能融合蛋白，融合了转化生长因子β受体II (TGF-βRII) 的细胞外域与人源IgG1单克隆抗体 (mAb) 致程序性细胞死亡配体阻断功能。该化合物主要用于癌症研究领域。
T75716	Disitertide TFA
	Disitertide (P144) TFA 是转化生长因子TGFβ1的多肽抑制剂，特异性的阻断其与受体间的相互作用。Disitertide TFA 也是PI3K 的抑制剂和凋亡 (apoptosis) 诱导剂。
T77076	Luspatercept
	Luspatercept (ACE-536) 是一种重组修饰的 ActRIIB 融合蛋白，与转化生长因子β超家族配体结合，通过与GDF11结合抑制Smad2/3信号通路，从而增加红细胞数量并促进红细胞前体成熟，用于贫血的研究。
T78585	Pentabromopseudilin
	Pentabromopseudilin (PBrP) 为自Pseudomonas bromoutilis与Alteromonas luteoviolaceus两种海洋细菌中提取的海洋抗生素，展现抗菌、抗肿瘤及植物毒性活性。此化合物为肌球蛋白 Va(Myosin Va, MyoVa)的可逆构型抑制剂，并能有效抑制转化生长因子-β(Transforming Growth Factor-β, TGF-β)的活性，适用于纤维化疾病与癌症研究领域。
T63498	ALK5-IN-6
	ALK5-IN-6 是 ALK5 的有效抑制剂。 ALK5-IN-6 具有潜力进行 TGF-β 相关疾病和病症的研究，包括但不限于肿瘤、炎症性疾病、纤维化疾病、自身免疫性疾病等。其中转化生长因子 β (TGF-β) 是一种多功能细胞因子，通过细胞表面的复杂受体信号通路以自分泌、旁分泌和内分泌的方式参与调控细胞增殖、分化和凋亡。
T62205	Pparδ agonist 7
	Pparδ agonist 7 是一种 Pparδ 的有效激动剂。其中过氧化物酶体增殖物激活受体 (PPAR) 属于核内受体转录因子超家族，在体内代谢稳态、炎症、细胞生长和分化的调节中发挥着关键作用。Pparδ agonist 7 对非酒精性脂肪肝 (NAFLD) 表现出研究潜力。
T74415	Imlunestrant tosylate
	Imlunestrant (LY-3484356) tosylate 是口服有效且选择性的雌激素受体(estrogen receptor, ER)降解剂(SERD)，具纯拮抗性。该化合物能持续抑制ER依赖的基因转录与细胞生长，适用于研究ER阳性(ER+)晚期乳腺癌(aBC)与子宫内膜样癌(EEC)。
T63114	ALK5-IN-7
	ALK5-IN-7 是一种 ALK5 的有效抑制剂。转化生长因子 β (TGF-β) 是一种多功能细胞因子，能够利用细胞表面的复杂受体信号通路，通过自分泌、旁分泌和内分泌的方式参与调控细胞增殖、分化和凋亡。ALK5-IN-7 具有潜力进行 TGF-β 相关疾病和病症的研究（包括但不限于肿瘤、纤维化疾病、炎症性疾病、自身免疫性疾病等）。
T79560	22-(4′-py)-JA 22-(4′-Pyridinecarbonyl) jorunnamycin A	Akt	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	22-(4′-py)-JA是久那霉素A的半合成衍生物，源自泰国蓝海绵（Xestospongia sp.）。该化合物显示出抗转移活性，能抑制AKT/mTOR/p70S6K信号通路，并阻断人脐静脉内皮细胞（HUVEC）中肿瘤细胞侵袭及管形成作用。它通过下调金属蛋白酶（MMP-2和MMP-9）、缺氧诱导因子1α（HIF-1α）和血管内皮生长因子（VEGF）来发挥作用。此外，22-(4′-py)-JA对非小细胞肺癌（NSCLC）显示出显著的抗癌效果。
T83951	TM2 TEAD inhibitor
	TM2 TEAD抑制剂是一种有效并且可逆的TEA领域转录因子抑制剂(IC50为TEAD4自动棕榈酰化和TEAD2棕榈酰化分别为38 nM和156 nM)。它抑制TEAD-YAP的结合和转录活性。TM2 TEAD抑制剂在YAP依赖型癌症细胞中，无论是单独使用还是与MEK抑制剂联合使用，都显示出强大的抗增殖效果。同时抑制体外YAP依赖的肝脏类器官生长。
T21763	Lenalidomide hydrochloride
	Lenalidomide hydrochloride (CC-5013 hydrochloride) 是 Thalidomide 的衍生物，也是一种具有口服活性免疫调节剂，以分子胶的方式作用。Lenalidomide hydrochloride (CC-5013 hydrochloride) 是一种泛素 E3 连接酶 cereblon (CRBN) 的配体，通过 CRBN-CRL4 泛素连接酶对两种淋巴转录因子 IKZF1 和 IKZF3 进行选择性泛素化和降解。Lenalidomide hydrochloride (CC-5013 hydrochloride) 特异性抑制成熟 B 细胞淋巴瘤 (包括多发性骨髓瘤) 的生长，并诱导 T 细胞释放白细胞介素-2 (IL-2)。
T81942	Lenalidomide sodium CC-5013 sodium
	Lenalidomide (sodium)是Thalidomide的衍生物，这种口服活性的免疫调节剂通过分子胶模式作用。作为泛素E3连接酶cereblon(CRBN)的配体，Lenalidomide (sodium)通过CRBN-CRL4泛素连接酶复合体，针对淋巴转录因子IKZF1和IKZF3进行选择性泛素化和降解。此外，Lenalidomide (sodium)有效抑制成熟B细胞淋巴瘤的增长，如多发性骨髓瘤，并能促使T细胞分泌白细胞介素-2(IL-2)。
T67921	Retinoic acid-d5 all-trans-Retinoic acid-d5,Isotretinoin-d5,Vitamin A acid-d5,Accutane-d5,ATRA-d5	Retinoid Receptor	Metabolism
	Retinoic acid-d5 (Vitamin A acid-d5)是视黄酸的氘标记形式。视黄酸是一种天然的RAR 核受体激动剂，对 RARα/β/γ 的 IC50 为 14 nM，与 PPARβ/δ 结合的Kd 为 17 nM。视黄酸是维生素a 的代谢物，在细胞生长、分化和器官发育中起着重要作用。视黄酸通过激活视黄酸受体α作为转录因子Nrf2的抑制剂来发挥作用。
T83825	Trofinetide acetate NNZ-2566
	Trofinetide是一种衍生自具有神经保护作用的三肽Gly-Pro-Glu的化合物，后者是胰岛素样生长因子-1（IGF-1）的N-端序列。在10 nM的浓度下使用时，它能减少由蛋白磷酸酶抑制剂奥卡达酸在原代大鼠胚胎纹状体神经元中引起的细胞死亡。Trofinetide在一种由穿透性弹道样脑损伤引起的大鼠神经炎症模型中减少了编码IL-1β、TNF-α、IL-6和E-selectin的mRNA的脑表达。在通过中脑动脉闭塞（MCAO）引起的大鼠脑损伤模型中，以30和60 mg/kg的剂量给药时，它减少了皮层和纹状体梗塞区域。Trofinetide（每天100 mg/kg）减少了树突棘的数量，并逆转了在fmr1-/-敲除小鼠脆性X综合征模型中的社交识别和情景恐惧条件反射的缺陷，同时也减少了睾丸重量的增加。含有Trofinetide的制剂已被用于治疗Rett综合征。

化合物

Cat.No: T1763

Synonym: SB525334

Target: ALK, TGF-beta/Smad

Cat.No: T4662

Target: TGF-beta/Smad

Cat.No: T13604

Target: Others, NF-κB, Nrf2

Cat.No: T76866

Synonym: LY 3012212,IMC-18F1

Target: VEGFR

Disitertide acetate

Cat.No: T11052L

Synonym: P144 acetate,Disitertide acetate(272105-42-7 Free base)

Target: TGF-beta/Smad

Cat.No: T62483

Target: TGF-beta/Smad

Cat.No: T76681

Synonym: GC1008

Target: TGF-beta/Smad

Cat.No: T4013

Target: Histone Methyltransferase

Cat.No: T19710

Synonym: Ciglitazona,U 63287,ADD3878,ADD-3878,U-63287,ADD 3878

Target: Apoptosis, p38 MAPK, PPAR

Cat.No: T60596

Disitertide diammonium

Cat.No: T75717

PPARδ agonist 8

Cat.No: T62277

Bintrafusp alfa

Cat.No: T80588

Synonym: M7824,MSB0011359C

Disitertide TFA

Cat.No: T75716

Cat.No: T77076

Pentabromopseudilin

Cat.No: T78585

Cat.No: T63498

Pparδ agonist 7

Cat.No: T62205

Imlunestrant tosylate

Cat.No: T74415

Cat.No: T63114

22-(4′-py)-JA

Cat.No: T79560

Synonym: 22-(4′-Pyridinecarbonyl) jorunnamycin A

Target: Akt

TM2 TEAD inhibitor

Cat.No: T83951

Lenalidomide hydrochloride

Cat.No: T21763

Lenalidomide sodium

Cat.No: T81942

Synonym: CC-5013 sodium

Retinoic acid-d5

Cat.No: T67921

Synonym: all-trans-Retinoic acid-d5,Isotretinoin-d5,Vitamin A acid-d5,Accutane-d5,ATRA-d5

Target: Retinoid Receptor

Trofinetide acetate

Cat.No: T83825

Synonym: NNZ-2566

Cat. No.	Product Name	Target	Signaling Pathways
T2798	Esculetin 秦皮乙素,二羟基香豆素,Aesculetin,Cichorigenin	Lipoxygenase; Akt; PI3K	Cytoskeletal Signaling; Metabolism; PI3K/Akt/mTOR signaling
	Esculetin (Cichorigenin) 是主要提取自水曲柳的树皮中的活性成分。它能够抑制PI3K/Akt 途径，阻碍血小板衍生生长因子诱导的气道平滑肌细胞表型转换。它具有抗氧化，抗炎和抗肿瘤的活性。
T1331	Riboflavin phosphate sodium Riboflavin 5'-phosphate sodium,核黄素磷酸钠(维生素B2),Vitamin B2 Phosphate Sodium Salt,Flavin mononucleotide,FMN,核黄素磷酸钠,FMN-Na,riboflavin-5'-phosphate	Endogenous Metabolite	Metabolism
	Riboflavin phosphate sodium (FMN) 是 riboflavin 的磷酸钠盐形式，riboflavin 是一种水溶性和必需的微量营养素，是自然产生的维生素B复合物的主要生长促进因子。Riboflavin phosphate sodium 转化为2种辅酶，黄素单核苷酸(FMN)和黄素腺嘌呤二核苷酸(FAD)，这两种辅酶通过帮助脂肪、碳水化合物和蛋白质的代谢来产生能量，并且是红细胞形成和呼吸、抗体产生以及调节人体生长和繁殖所必需的。
TN1567	Delphinidin chloride	Estrogen Receptor/ERR; VEGFR	Angiogenesis; Endocrinology/Hormones; Tyrosine Kinase/Adaptors
	Delphinidin chloride 是一种花青素，是一种可从浆果和红酒中分离得到的天然植物色素，是某些花青素的前体。Delphinidin chloride 诱导血管内皮释放一氧化氮，引起血管松弛。在1 ~ 40 μM 剂量下，对上皮生长因子受体的信号传导和雌激素受体α的表达有抑制作用，与细胞凋亡和自噬有关。Delphinidin chloride 能调节 JAK/STAT3 和 MAPKinase 信号传导。Delphinidin 还能抑制 p300/CBP 的组蛋白乙酰转移酶活性(IC50 在约为30 μM)
T75526	Chlorfortunone A
	Chlorfortunone A 是一种新的倍半萜类二聚体，可从 Chloranthus fortunei 的根中分离得到。Chlorfortunone A 能够抑制细胞转化生长因子 (TGF) β 的活性。
T75487	7-Hydroxyneolamellarin A
	7-Hydroxyneolamellarin A，一种从海绵Dendrilla nigra 提取的天然产物，是高效的缺氧诱导因子 1α (HIF-1α) 抑制剂。该化合物能够减弱HIF-1α蛋白的积累，并抑制血管表皮生长因子 (VEGF) 的转录活性，因而在癌症研究中有应用价值。
TN5153	Torilin	MMP; ERK; IκB/IKK; p38 MAPK; NF-κB; Tyrosinase; Reductase; DNA/RNA Synthesis; JNK	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Endocrinology/Hormones; MAPK; Metabolism; NF-κB; Proteases/Proteasome
	Torilin 是一种睾酮5α还原酶抑制剂，它（IC50=31.7+/-4.23μM）对5α还原酶的抑制作用强于α-亚麻酸（IC50=160.3+/-24.62μM），但弱于非那雄胺（IC50=0.38+/-0.06μM）。Torilin 具有免疫调节、肝脏保护和抗炎特性，它通过限制 TAK1介导的 MAP 激酶和 NF-βB 活化来抑制炎症，它可以减轻关节炎的严重程度，改变 dLN 或关节中的白细胞活化，并恢复血清和脾细胞细胞因子失衡。托利林抑制α-黑素细胞刺激激素激活的 B16黑色素瘤细胞中的黑色素生成，IC（50）值为25μM。Torilin 对枯草芽孢杆菌 ATCC 6633孢子和营养细胞表现出优异的抗菌活性。Torilin 在体内和体外都具有强大的抗血管生成活性，它可能通过抑制肿瘤侵袭来抑制肿瘤发生，逆转癌细胞的多药耐药性，它可以增强阿霉素、长春碱、紫杉醇和秋水仙碱对多药耐药 KB-V1和 MCF7/ADR 细胞的细胞毒性。

天然产物

Cat.No: T2798

Synonym: 秦皮乙素,二羟基香豆素,Aesculetin,Cichorigenin

Target: Lipoxygenase, Akt, PI3K

Riboflavin phosphate sodium

Cat.No: T1331

Synonym: Riboflavin 5'-phosphate sodium,核黄素磷酸钠(维生素B2),Vitamin B2 Phosphate Sodium Salt,Flavin mononucleotide,FMN,核黄素磷酸钠,FMN-Na,riboflavin-5'-phosphate

Target: Endogenous Metabolite

Delphinidin chloride

Cat.No: TN1567

Target: Estrogen Receptor/ERR, VEGFR

Chlorfortunone A

Cat.No: T75526

7-Hydroxyneolamellarin A

Cat.No: T75487

Cat.No: TN5153

Target: MMP, ERK, IκB/IKK, p38 MAPK, NF-κB, Tyrosinase, Reductase, DNA/RNA Synthesis, JNK

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03958	TGF alpha Protein, Human, Recombinant transforming growth factor α,转化生长因子,transforming gr...	Human	E. coli
	The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (...
TMPY-03945	Latent TGF beta 1 Protein, Rat, Recombinant (His) TGF β1,transforming growth factor, β1,transforming growth fa...	Rat	HEK293 Cells
	Latent TGF beta 1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P17246.
TMPY-00608	TGF beta 1 Protein, Rat/Mouse, Recombinant transforming growth factor, beta 1,transforming growth facto...	Mouse,Rat	HEK293 Cells
	TGF beta 1 Protein, Rat/Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 12.8 kDa.
TMPY-04211	Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) transforming growth factor, β1,TGF β1,transforming growth fa...	Cynomolgus	HEK293 Cells
	Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa.
TMPY-02638	TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant transforming growth factor, beta 1,转化生长因子,transform...	Human,Rhesus,Cynomolgus,Canine	CHO Cells
	TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 12.8 kDa and the accession number is A0A499FJK2.
TMPY-06355	Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His) 转化生长因子,TGF β1 & GARP Heterotrimer	Human	HEK293 Cells
	Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 108.72 kDa and the accession number is P01137.
TMPY-00500	Latent TGF beta 1 Protein, Mouse, Recombinant (His) transforming growth factor, beta 1,TGF β1,Tgfb-1,TGF-beta1,<...	Mouse	HEK293 Cells
	Latent TGF beta 1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P04202.
TMPY-06247	TGF beta 3 Protein, Human, Recombinant (hFc) TGF-beta 3,ARVD,TGF β3,TGF-β3,TGF-beta3,transforming growth ...	Human	HEK293 Cells
	TGF beta 3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.2 kDa and the accession number is P10600-1.
TMPY-01133	Latent TGF beta 1 Protein, Human, Recombinant (His) CED,DPD1,transforming growth factor, beta 1,TGF β1,LAP,转...	Human	HEK293 Cells
	Latent TGF beta 1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2.
TMPJ-00255	TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated ARVD,TGF-β3,TGFB3,转化生长因子,TGF-beta3	Human	HEK293 Cells
	TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with N-Avi tag. The predicted molecular weight is 10-14 KDa and the accession number is P10600.
TMPJ-00249	TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated TGF-Beta-1,TGFB1,Transforming Growth Factor β-1,Latency-Asso...	Human	HEK293 Cells
	Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family...
TMPY-00413	Latent TGF beta 2 Protein, Mouse, Recombinant (His) Tgfb-2,Tgf-beta2,TGF-beta 2,Tgf-β2,TGFB2,TGF-β2,TGF β2,转...	Mouse	HEK293 Cells
	TGF beta 2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.9 kDa and the accession number is P27090.
TMPK-00757	TGF alpha Protein, Human, Recombinant (hFc) TGF type 1,TGFA,TGF-alpha,TGF-α,ETGF,转化生长因子	Human	HEK293 Cells
	Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) and of nonsyndromic cleft palate only (NS-CPO). Biologic support for a role of TGFA arises from its presence at high levels in the epithelial tissue of the medial edge of the palatal shelves at the time of shelf fusion in mice. TGF alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted ...
TMPK-00888	TGF alpha Protein, Mouse, Recombinant (hFc) TGF type 1,转化生长因子,TGF-alpha,TGF-α,ETGF,TGFA	Mouse	HEK293 Cells
	Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) and of nonsyndromic cleft palate only (NS-CPO). Biologic support for a role of TGFA arises from its presence at high levels in the epithelial tissue of the medial edge of the palatal shelves at the time of shelf fusion in mice. TGF alpha Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted ...
TMPY-00229	Latent TGF beta 1 Protein, Canine, Recombinant (His) transforming growth factor, β1,transforming growth factor, b...	Canine	HEK293 Cells
	Latent TGF beta 1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.4 kDa.
TMPJ-00258	TGF beta 2 Protein, Human, Recombinant Glioblastoma-derived T-cell suppressor factor,TGF-β-2,Transf...	Human	HEK293 Cells
	Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be...
TMPJ-00261	TGF beta 2 Protein, Mouse/Rat, Recombinant transforming growth factor β-2,BSC-1 cell growth inhibitor,G...	Mouse,Rat	HEK293 Cells
	Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the n...
TMPK-00258	Latent TGF beta 3 Protein, Human, Recombinant (His) TGFβ3,转化生长因子,TGF-β3,TGF-beta3,TGFβ,TGF-β,ARVD,TGFB3...	Human	HEK293 Cells
	Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differentiation. And transforming growth factor beta3 (TGFbeta3) is a key protein involved in scar-free healing observed in embryos. Latent TGF beta 3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 45.9 kDa and t...
TMPK-00259	Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated TGF-beta3,TGFβ,TGF-β,TGF-β3,TGFB3,ARVD,TGFβ3,转化生长因子...	Human	HEK293 Cells
	Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differentiation. And transforming growth factor beta3 (TGFbeta3) is a key protein involved in scar-free healing observed in embryos. Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predi...
TMPY-05313	Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated transforming growth factor, beta 1,transforming growth facto...	Mouse	HEK293 Cells
	Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P04202.
TMPJ-00772	Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated Transforming growth factor β-1,Latent TGF-β1,TGFB1,Transform...	Mouse	HEK293 Cells
	Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 13 and 35-45 KDa and the accession number is P04202.
TMPY-00231	TGF beta 2 Protein, Canine, Recombinant (His) transforming growth factor β2,转化生长因子,TGF-beta 2,TGF...	Canine	HEK293 Cells
	TGF beta 2 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is A0A8C0RRP5.
TMPJ-00622	Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) 转化生长因子,Transforming growth factor β-1,Latent TGF-β1...	Cynomolgus	HEK293 Cells
	Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 11 and 35-45 KDa and the accession number is F7HCV5.
TMPY-04577	TGF beta 2 Protein, Rhesus, Recombinant (His) TGF-beta 2,transforming growth factor beta 2,transforming gr...	Rhesus	HEK293 Cells
	TGF beta 2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is F6ZJW6.
TMPJ-00260	Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated TGFB2,TGF-β-2,TGF-beta-2,Transforming growth factor beta-2 p...	Human	HEK293 Cells
	Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 13 and 39-50 KDa and the accession number is P61812.
TMPJ-00256	Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated Transforming growth factor β-3,Latent TGF-β3,TGF-β-3,TGFβ3,T...	Human	HEK293 Cells
	Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 12 and 37-45 KDa and the accession number is P10600.
TMPY-05521	Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated TGFB,TGF β1,转化生长因子,TGF-beta 1,transforming growth f...	Human	HEK293 Cells
	Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2.
TMPY-05314	TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated transforming growth factor β2,TGF β2,转化生长因子,Tgfb-2,...	Mouse	HEK293 Cells
	TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.9 kDa and the accession number is P27090.
TMPJ-00259	TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated G-TSF,转化生长因子,Cetermin,Transforming growth factor be...	Human	HEK293 Cells
	TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with N-Avi tag. The predicted molecular weight is 10-14 KDa and the accession number is P61812.
TMPJ-00771	TGF beta 1 Protein, Mouse/Rat, Recombinant TGFB,TGFbeta,CEDLAP,TGF-beta-1,TGF-beta 1 protein,latency-as...	Mouse,Rat	HEK293 Cells
	Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II)...

重组蛋白

TGF alpha Protein, Human, Recombinant

Cat.No: TMPY-03958

Species: Human

Expression System: E. coli

Latent TGF beta 1 Protein, Rat, Recombinant (His)

Cat.No: TMPY-03945

Species: Rat

Expression System: HEK293 Cells

TGF beta 1 Protein, Rat/Mouse, Recombinant

Cat.No: TMPY-00608

Species: Mouse,Rat

Expression System: HEK293 Cells

Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-04211

Species: Cynomolgus

Expression System: HEK293 Cells

TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant

Cat.No: TMPY-02638

Species: Human,Rhesus,Cynomolgus,Canine

Expression System: CHO Cells

Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His)

Cat.No: TMPY-06355

Species: Human

Expression System: HEK293 Cells

Latent TGF beta 1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00500

Species: Mouse

Expression System: HEK293 Cells

TGF beta 3 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06247

Species: Human

Expression System: HEK293 Cells

Latent TGF beta 1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01133

Species: Human

Expression System: HEK293 Cells

TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated

Cat.No: TMPJ-00255

Species: Human

Expression System: HEK293 Cells

TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated

Cat.No: TMPJ-00249

Species: Human

Expression System: HEK293 Cells

Latent TGF beta 2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00413

Species: Mouse

Expression System: HEK293 Cells

TGF alpha Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00757

Species: Human

Expression System: HEK293 Cells

TGF alpha Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00888

Species: Mouse

Expression System: HEK293 Cells

Latent TGF beta 1 Protein, Canine, Recombinant (His)

Cat.No: TMPY-00229

Species: Canine

Expression System: HEK293 Cells

TGF beta 2 Protein, Human, Recombinant

Cat.No: TMPJ-00258

Species: Human

Expression System: HEK293 Cells

TGF beta 2 Protein, Mouse/Rat, Recombinant

Cat.No: TMPJ-00261

Species: Mouse,Rat

Expression System: HEK293 Cells

Latent TGF beta 3 Protein, Human, Recombinant (His)

Cat.No: TMPK-00258

Species: Human

Expression System: HEK293 Cells

Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

Cat.No: TMPK-00259

Species: Human

Expression System: HEK293 Cells

Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated

Cat.No: TMPY-05313

Species: Mouse

Expression System: HEK293 Cells

Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00772

Species: Mouse

Expression System: HEK293 Cells

TGF beta 2 Protein, Canine, Recombinant (His)

Cat.No: TMPY-00231

Species: Canine

Expression System: HEK293 Cells

Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPJ-00622

Species: Cynomolgus

Expression System: HEK293 Cells

TGF beta 2 Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-04577

Species: Rhesus

Expression System: HEK293 Cells

Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00260

Species: Human

Expression System: HEK293 Cells

Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00256

Species: Human

Expression System: HEK293 Cells

Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05521

Species: Human

Expression System: HEK293 Cells

TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated

Cat.No: TMPY-05314

Species: Mouse

Expression System: HEK293 Cells

TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated

Cat.No: TMPJ-00259

Species: Human

Expression System: HEK293 Cells

TGF beta 1 Protein, Mouse/Rat, Recombinant

Cat.No: TMPJ-00771

Species: Mouse,Rat

Expression System: HEK293 Cells

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