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Search Results for " sterol "

92

抑制剂 & 化合物

72

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T4039	BIBB 515	Others	Others
	BIBB 515 是口服具有活力的 2,3-氧化角鲨烯环化酶选择性抑制剂，在大鼠和小鼠中的 ED50值分别为 0.2-0.5 mg/kg 和 0.36-33.3 mg/kg (1-5 小时)。它主要利用抑制低密度脂蛋白的产生，从而发挥降脂作用。
T20237	Fenhexamid Elevate,Teldor,环酰菌胺	Antifungal	Microbiology/Virology
	Fenhexamid (Elevate) 是一种甾醇生物合成抑制剂，对植物病原真菌具有抗真菌活性。 Fenhexamid 用于农业，并在水果和蔬菜中以可测量的量存在。
T20691	Fenpropidin 苯锈啶,Ro12-3049,Ro-12-3049,Ro 12-3049	Antifungal	Microbiology/Virology
	Fenpropidin (Ro-12-3049) 是甾醇类生物合成的抑制剂，具有杀菌的活性。
T70931	SYK-IN-II
	SYK-IN-II is an inhibitor of the spleen tyrosine kinase (STK).
T41008	BODIPY-Cholesterol BCh2
	BODIPY-Cholesterol (TF-Chol)是一种带有荧光 BODIPY 基团和细胞通透性的胆固醇类似物，是一种新型 BODIPY 胆固醇探针。BODIPY-Cholesterol 可用于研究细胞内固醇摄取和细胞器间固醇通量。
T65554	cholesterol-absorption inhibitor Intermediate 2	Others	Others
	cholesterol-absorption inhibitor Intermediate 2 是一种有效且具有口服活性的胆固醇吸收抑制剂，可降低血液中胆固醇含量。
T69467	Azacosterol IMD760,Diazasterol	Others	Others
	Azacosterol (Diazasterol) 是一种DHCR24抑制剂。Azacosterol 口服或腹腔注射后会在皮质神经元中发生一系列反应。
T60796	Cholesterol 24-hydroxylase-IN-1	P450	Metabolism
	Cholesterol 24-hydroxylase-IN-1 是一种能透过血脑屏障且具有口服活性、选择性和高效性的的胆固醇24-羟化酶(CH24H or CYP46A1)抑制剂。Cholesterol 24-hydroxylase-IN-1 可用于研究癫痫类的神经系统疾病。
T35973	Cholesterol-5α,6α-epoxide Epoxycholesterol,5α,6α-epoxy Cholestanol,NSC 18176	Others	Others
	Cholesterol-5α,6α-epoxide (Epoxycholesterol) 是胆固醇氧化产生的代谢产物。在应用他莫昔芬和 PBPE 后，5α,6α-环氧胆甾烷醇通过与 LXRβ 结合诱导三酰甘油生物合成。
T21417	Dihydrotachysterol Hytakerol,HSDB-3314,双氢速甾醇,HSDB3314,Parterol,HSDB 3314
	Dihydrotachysterol (DHT) is a biologically active synthetic analog of vitamin D. It promotes intestinal absorption of active calcium and phosphate . It is also beneficial in the treatment of hypoparathyroidism.
T34528	Sarcosterol
	Sarcosterol is a marine sterol from the soft coral Sinularia mayi.
T34092	Pneumocysterol
	Pneumocysterol is a sterol detected in the opportunistic pathogen Pneumocystis carinii hominis.
T37858	Dehydroergosterol 9,11-dehydro Ergosterol,DHE
	Dehydroergosterol is a naturally occurring, fluorescent analog of cholesterol (ex/em = 324/375 nm) that mimics the properties of cholesterol in cell membranes.[1] It is readily bound by cholesterol-binding proteins and has been used for real-time probing of the sterol environment and to elucidate intracellular sterol trafficking in living organisms.[1]
T10167	5-Dehydroepisterol	Others	Others
	5-Dehydroepisterol is an episterol derivative with anti-fungal activities. It can be formed by C-5 sterol desaturase and converted into 24-methylenecholesterol by 7-dehydrocholesterol reductase.
T32847	Lokysterolamine A
	Lokysterolamine A is a steroidal alkaloid isolated from a sponge, Corticium sp.
T29729	Agosterol A
	Agosterol A is isolated from marine sponge Spongia.
T76139	Cholesterol esterase
	胆固醇酯酶 (Cholesterol esterase) 是一种在肠道内将胆固醇酯水解为胆固醇和游离脂肪酸的酶。胆固醇在腺泡细胞中合成，储存在酶原颗粒中。胆固醇酯酶又称胆盐刺激脂肪酶、羧基酯脂肪酶，具有促进胆固醇吸收的作用。
T21530	4β-hydroxy Cholesterol
	4β-hydroxy Cholesterol 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T21530，CAS号为 17320-10-4。
T35977	6α-hydroxy Cholesterol 6α-hydroxy Cholesterol,6α-OHC
	6α-hydroxy Cholesterol is an oxysterol that increases superoxide anion production in SK-N-BE cells when used at concentrations of 50 and 100 μM.[1]
T70933	Weinbersterol disulfate A
	Weinbersterol disulfate A is a derivatives of 2beta,3alpha-dihydroxy-5alpha-cholestane. It has shown inhibitory action against HSV-2. and proved to be active against DEN-2 and JV.
T29728	Agnosterol
	Agnosterol is a bioactive chemical.
T32848	Lokysterolamine B N-Acetyl-4beta-hydroxy-epi-plakinamine A
	Lokysterolamine B is a steroidal alkaloid isolated from a sponge, Corticium sp.
T68864	Saringosterol
	Saringosterol, also known as Saningosterol and Cystosphaerol, is a selective LXRβ agonist. Saringosterol is racmic at the 24-position.
T38996	4α-Methylcholesterol
	4α-Methylcholesterol, a derivative of Cholesterol, possesses the ability to oxidize 3-hydroxy steroid at an apparent K m of 12.6 μM.
T82411	Fecosterol
	Fecosterol为酿酒酵母的代谢产物，应用于植物甾醇血症的研究领域。
T38556	Larsucosterol sodium DUR-928 sodium
	Larsucosterol sodium is a cholesterol metabolite from the nuclei of normal human liver tissues, epigenetically regulates the transcription of proteins and enzymes involved in lipid synthesis, inflammation, and apoptosis.
T76128	Cholesterol oxidase
	Cholesteroloxidase (ChOx)，一种含有FAD的细菌黄素氧化酶，主要应用于生化研究领域。该酶专门催化胆固醇（及其他甾醇）的C(3)-OH基团，氧化生成cholest-5-en-3-one，并进一步异构化为cholest-4-en-3-one。
T34283	Remeisterol
	Remeisterol is a biochemical.
T22399	Phytosterols	Others	Others
	Phytosterols, also called stanol esters or plant sterols, are specialized compounds found in plants that are structurally similar to cholesterol found in humans.
T71756	24(S),25-Epoxycholesterol
	24(S),25-Epoxycholesterol is an oxysterol agonist of the liver X receptor.
T31463	Dihydroagnosterol NSC107127,NSC-107127,NSC 107127
	Dihydroagnosterol is a bioactive chemical.
T82731	Cholesterol 24-hydroxylase-IN-2
	Cholesterol24-Hydroxylase-IN-2为胆固醇24-羟化酶（CH24H 或CYP46A1）抑制剂，具有5.4 nM的IC50值。该化合物适用于哺乳动物胆固醇24-羟化酶的成像研究。
T31010	Coprosterol Koprosterin,Stercorin,Koprosterol
	Coprosterol is a stanol formed from the biohydrogenation of cholesterol as a biomarker for the presence of human faecal matter in the environment.
T38045	Cholesterol β-D-Glucoside
	Cholesterol β-D-glucoside is a derivative of cholesterol that contains β-D-glucose . It is formed from cholesterol and glucosylceramide by β-glucosidase 1. It activates heat shock transcription factor 1 (Hsf1) in response to heat shock, which increases the expression of heat shock protein 70 (Hsp70) in TIG-3 human fetal lung fibroblasts when used at a concentration of 10 μM. Cholesterol β-D-glucoside (100 mg/kg) prevents ulcer formation following cold-restraint stress and increases Hsf1 activity...
T74147	Larsucosterol (trimethylamine)
	Larsucosterol (DUR-928) trimethylamine，一种胆固醇代谢物，有效的肝 X 受体 (LXR) 拮抗剂，同时作为内源性脂肪生成的调节剂。该化合物通过下调 mRNA 水平和抑制 SREBP-1 的激活，有效抑制胆固醇的生物合成。
T77231	Cholesterol nervonate
	Cholesterolnervonate 是一种生化试剂，可作为生物材料或有机化合物，用于生命科学相关研究。
T25930	Penasterol
	Penasterol suppresses IgE-dependent histamine release.
T77270	Cholesterol-PEG-Folate (MW 2000)
	Cholesterol-PEG-Folate (MW 2000) 是一种辅料，可用于制备叶酸偶联 PEG 脂质体。
T36998	7β,27-dihydroxy Cholesterol 7β,27-DHC,7β,27-dihydroxy Cholesterol
	7β,27-dihydroxy Cholesterol is an oxysterol and agonist of retinoic acid receptor-related orphan receptor γ (RORγ) and RORγt. [1] It activates RORγ- or RORγt-dependent signaling with EC50 values of 691 and 1,045 nM, respectively, in reporter assays using HEK293T cells expressing the recombinant human receptors. 7β,27-dihydroxy Cholesterol is selective for RORγ and RORγt over a panel of eight additional nuclear receptors at 30 &#181M. It increases IL-17A production in Th17-polarized isolated hum...
T40140	Zanamivir-Cholesterol Conjugate
	Zanamivir-cholesterol conjugate is an extended-duration neuraminidase inhibitor highly effective against drug-resistant influenza strains.
T71133	Azacosterol hydrochloride
	Azacosterol is a diaza derivative of cholesterol which acts as a hypocholesteremic agent by blocking delta-24-reductase causing accumulation of desmosterol. Azacosterol acts as an inhibitor of 24-dehydrocholesterol reductase (24-DHCR), preventing the formation of cholesterol from desmosterol. Although it primarily acts to inhibit 24-DHCR, the drug also inhibits other steps in cholesterol biosynthesis. The antifertility effects of the drug in birds are mediated by inhibition of steroid hormone pr...
T39184	Tachysterol 3
	Tachysterol 3 is a side product in vitamin D photosynthesis.
T77264	Thiocholesterol
	Thiocholesterol 是一种胆固醇衍生物，常用于合成阳离子脂质液态晶体 (CLCs)。它也作为纳米银 (SNP) 的有效稳定剂。此外，Thiocholesterol 在质膜研究和药物递送领域有重要应用。
T41015	Larsucosterol DUR-928
	Larsucosterol is a cholesterol metabolite from the nuclei of normal human liver tissues, epigenetically regulates the transcription of proteins and enzymes involved in lipid synthesis, inflammation, and apoptosis.
T35502	δ7-Avenasterol
	δ7-Avenasterol is a phytosterol that has been found in a variety of plant oils and grains, including olive and soybean oils and wheat, oats, and rye, and has antioxidant activities.1,2It reduces temperature-induced oxidation of safflower oil.3
T65073	Cholesterol n-Octanoate
	Cholesterol n-Octanoate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65073，CAS号为 1182-42-9。
T36217	19-hydroxy Cholesterol
	19-hydroxy Cholesterol is formed during metabolic oxidation of cholesterol. It has been used as an internal standard for the quantitative determination of sterols by mass spectroscopic analysis.[1]
T36130	22(S)-hydroxy Cholesterol 22(S)-hydroxy Cholesterol,22β-hydroxy Cholesterol
	22(S)-hydroxy Cholesterol is a synthetic oxysterol and a modulator of the liver X receptor (LXR). [1] t prevents monocyte chemoattractant protein 1 (MCP-1) expression induced by the LXR agonist GW 3965 in primary hepatocytes and downregulates mRNA expression of the LXR target genes CD36, ACSL1, and SCD-1 in human myotubes. It decreases triacylglycerol and diacylglycerol synthesis from labeled palmitate and acetate, respectively, in human myoblasts by 50% when used at a concentration of 10 uM. 22...
T40601	Lumisterol 3 (>90%) CholecalciferolEPImpurityA,Lumisterol 3 (>90%),9β,10α-Cholesta-5,7-dien-3β-ol
	Lumisterol 3 (>90%; 9β,10α-Cholesta-5,7-dien-3β-ol) is a predominant secosteroid metabolite found in humans, belonging to the class of vitamin D3 photoisomer derivatives. It is utilized in the synthesis of vitamin D.
T124072	9,11-Dehydroergosterol peroxide
	9,11-Dehydroergosterol peroxide 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124072，CAS号为 86363-50-0。

化合物

Cat.No: T4039

Target: Others

Cat.No: T20237

Synonym: Elevate,Teldor,环酰菌胺

Target: Antifungal

Cat.No: T20691

Synonym: 苯锈啶,Ro12-3049,Ro-12-3049,Ro 12-3049

Target: Antifungal

Cat.No: T70931

BODIPY-Cholesterol

Cat.No: T41008

Synonym: BCh2

cholesterol-absorption inhibitor Intermediate 2

Cat.No: T65554

Target: Others

Cat.No: T69467

Synonym: IMD760,Diazasterol

Target: Others

Cholesterol 24-hydroxylase-IN-1

Cat.No: T60796

Target: P450

Cholesterol-5α,6α-epoxide

Cat.No: T35973

Synonym: Epoxycholesterol,5α,6α-epoxy Cholestanol,NSC 18176

Target: Others

Dihydrotachysterol

Cat.No: T21417

Synonym: Hytakerol,HSDB-3314,双氢速甾醇,HSDB3314,Parterol,HSDB 3314

Cat.No: T34528

Cat.No: T34092

Dehydroergosterol

Cat.No: T37858

Synonym: 9,11-dehydro Ergosterol,DHE

5-Dehydroepisterol

Cat.No: T10167

Target: Others

Lokysterolamine A

Cat.No: T32847

Cat.No: T29729

Cholesterol esterase

Cat.No: T76139

4β-hydroxy Cholesterol

Cat.No: T21530

6α-hydroxy Cholesterol

Cat.No: T35977

Synonym: 6α-hydroxy Cholesterol,6α-OHC

Weinbersterol disulfate A

Cat.No: T70933

Cat.No: T29728

Lokysterolamine B

Cat.No: T32848

Synonym: N-Acetyl-4beta-hydroxy-epi-plakinamine A

Cat.No: T68864

4α-Methylcholesterol

Cat.No: T38996

Cat.No: T82411

Larsucosterol sodium

Cat.No: T38556

Synonym: DUR-928 sodium

Cholesterol oxidase

Cat.No: T76128

Cat.No: T34283

Cat.No: T22399

Target: Others

24(S),25-Epoxycholesterol

Cat.No: T71756

Dihydroagnosterol

Cat.No: T31463

Synonym: NSC107127,NSC-107127,NSC 107127

Cholesterol 24-hydroxylase-IN-2

Cat.No: T82731

Cat.No: T31010

Synonym: Koprosterin,Stercorin,Koprosterol

Cholesterol β-D-Glucoside

Cat.No: T38045

Larsucosterol (trimethylamine)

Cat.No: T74147

Cholesterol nervonate

Cat.No: T77231

Cat.No: T25930

Cholesterol-PEG-Folate (MW 2000)

Cat.No: T77270

7β,27-dihydroxy Cholesterol

Cat.No: T36998

Synonym: 7β,27-DHC,7β,27-dihydroxy Cholesterol

Zanamivir-Cholesterol Conjugate

Cat.No: T40140

Azacosterol hydrochloride

Cat.No: T71133

Cat.No: T39184

Thiocholesterol

Cat.No: T77264

Cat.No: T41015

Synonym: DUR-928

δ7-Avenasterol

Cat.No: T35502

Cholesterol n-Octanoate

Cat.No: T65073

19-hydroxy Cholesterol

Cat.No: T36217

22(S)-hydroxy Cholesterol

Cat.No: T36130

Synonym: 22(S)-hydroxy Cholesterol,22β-hydroxy Cholesterol

Lumisterol 3 (>90%)

Cat.No: T40601

Synonym: CholecalciferolEPImpurityA,Lumisterol 3 (>90%),9β,10α-Cholesta-5,7-dien-3β-ol

9,11-Dehydroergosterol peroxide

Cat.No: T124072

Cat. No.	Product Name	Target	Signaling Pathways
TN6736	Dihydrolanosterol 24,25-Dihydrolanosterol,Lanostenol,二氢羊毛甾醇	Others	Others
	Dihydrolanosterol (24,25-Dihydrolanosterol) 是一种 CYP51 的底物，能够阻碍胆固醇的合成。
T4717	25-Hydroxycholesterol 25-羟基胆固醇,25-羟基胆甾醇	Others; Endogenous Metabolite; HMG-CoA Reductase	Metabolism; Others
	25-Hydroxycholesterol 是胆固醇的代谢产物，由巨噬细胞响应 Toll 样受体激活而分泌。它有效抑制 B 细胞产生 IgA，EC50约为 65 nM。
T4S2157	Campesterol 菜油甾醇,(24R)-5-Ergosten-3β-ol	Endogenous Metabolite	Metabolism
	Campesterol ((24R)-5-Ergosten-3β-ol) 是一种植物甾醇，具有降胆固醇和抗癌的活性。
T0760	Cholesterol Cholesterin,Cholesteryl alcohol,胆固醇	Estrogen Receptor/ERR; MRP; Endogenous Metabolite; ROR	Endocrinology/Hormones; Immunology/Inflammation; Metabolism
	Cholesterol (Cholesteryl alcohol) 属于天然产物，是哺乳动物中的主要固醇，是一种雌激素相关受体 α (ERRα) 的激动剂。Cholesterol 广泛存在于动物的细胞膜，也是合成几种重要荷尔蒙及胆酸的材料。
T4970	LANOSTEROL 羊毛甾醇,3β-Hydroxy-8,24-lanostadiene,8,24-Lanostadien-3β-ol	Endogenous Metabolite	Metabolism
	Lanosterol (3β-Hydroxy-8,24-lanostadiene) 是胆固醇合成的中间产物，能够诱导胆固醇合成的速率控制酶 HMG-CoA 还原酶的泛素化和降解。Lanosterol 可以抑制神经退行性疾病相关错误折叠蛋白的聚集和细胞毒性。
T10086	24-Hydroxycholesterol Cholest-5-ene-3beta,24-diol	Liver X Receptor; NMDAR	Metabolism; Neuroscience
	24-Hydroxycholesterol (Cholest-5-ene-3beta,24-diol) 是一种氧甾醇化合物，是一种 n-甲基-d-天门冬氨酸受体 (NMDA) 和转录因子 LXR 的激活剂，可用于研究心血管生成和胰腺癌。
T15720	Lathosterol	Endogenous Metabolite	Metabolism
	Lathosterol 是胆固醇样分子，其血清浓度是全身胆固醇合成的指标。
TN7127	5,6-Epoxyergosterol	Others	Others
	5,6-Epoxyergosterol 来源于内生真菌 Phyllosticta capitalensis。
T2966	Beta-Sitosterol Cupreol,谷甾醇,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,beta-谷甾醇,22,23-Dihydrostigmasterol,Betaprost	Apoptosis; Lipase; Endogenous Metabolite	Apoptosis; Metabolism
	Beta-Sitosterol (SKF 14463) 是一种植物甾醇，干扰细胞周期、细胞凋亡、增殖、存活、侵袭、血管生成和炎症等多种细胞信号通路。
T8040	Cholesterol myristate 胆甾烯基豆蔻酸酯,Cholesteryl myristate,胆固醇肉豆蔻酸,Cholesteryl tetradecanoate	Others; Potassium Channel; GABA Receptor; Endogenous Metabolite; AChR	Membrane transporter/Ion channel; Metabolism; Neuroscience; Others
	Cholesterol myristate (Cholesteryl myristate) 是粗吻海龙中的一种类固醇，可与多种离子通道结合，例如nAChR、GABAA 受体和内向整流钾离子通道。
T19161	7α-Hydroxycholesterol	Others	Others
	7α-Hydroxycholesterol 是一种由酶促氧化和非酶促氧化形成的胆固醇氧化物，可用作脂质过氧化的生物标志物。
T8184	Fucosterol 岩皂甾醇,岩藻甾醇	PARP; Endogenous Metabolite; PPAR	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	Fucosterol 是从藻类、海藻或硅藻中分离的一种甾醇，具有抗氧化、抗脂肪、降低血液胆固醇、抗糖尿病和抗癌活性。它通过抑制 PPARα和C/EBPα的表达调控脂肪生成，可用于抗肥胖试剂开发研究。
TN1377	α-Spinasterol Α-波菜甾醇,alpha-Spinasterol,菠甾醇	COX; Antibacterial; TRP/TRPV Channel	Immunology/Inflammation; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	α-Spinasterol 是一种从Spinacia oleracea 分离的瞬时受体电位香草酸 1 拮抗剂，具有抗菌、抗炎、抗抑郁、抗氧化和抗伤害作用。它抑制COX-1和COX-2活性，IC50值分别为 16.17 μM 和 7.76 μM。
TN6715	7-Ketocholesterol	Others	Others
	7-Ketocholesterol 是胆固醇的代谢物。
T19711	Desmosterol Desmesterol,24-Dehydrocholesterol	Endogenous Metabolite	Metabolism
	Desmosterol(24-Dehydrocholesterol) 是一种胆固醇生物合成中间体，抑制巨噬细胞炎症小体活化，防止血管炎症和动脉粥样硬化。
TC0027	beta-Sitosterol acetate	Others	Others
	beta-Sitosterol acetate 是几种被称为植物甾醇的植物性物质之一。
T3871	Daucosterol Alexandrin,Sitogluside,β-Sitosterol β-D-glucoside,Eleutheroside A,西托糖苷	Glucosidase	Metabolism
	Daucosterol (Sitogluside) 是天然的甾醇体类化合物。
TN7071	Ergosterol Acetate Ergosta-5,7,22-trien-3-beta-yl acetate	Others	Others
	Ergosterol Acetate (Ergosta-5,7,22-trien-3-beta-yl acetate) 是来自红曲霉的 Ergosterol 的乙酸酯衍生物之一。
T2912	Ergosterol 麦角固醇,Provitamin D,Ergosterin,Provitamin D2	Others; Endogenous Metabolite	Metabolism; Others
	Ergosterol (Provitamin D2) 是真菌中的主要固醇类，具有抗炎，抗氧化和抗增殖的作用。
T10085	20(S)-Hydroxycholesterol 20α-Hydroxycholesterol	Smo	Stem Cells
	20(S)-Hydroxycholesterol (20α-Hydroxycholesterol) 是平滑 (smo) 癌蛋白的变构激活剂。
TQ0274	27-Hydroxycholesterol 27-羟基胆固醇,5,25R-胆甾烯-3BETA,26-二醇,25(R)-27-hydroxy Cholesterol	Estrogen/progestogen Receptor; Liver X Receptor	Endocrinology/Hormones; Metabolism
	27-Hydroxycholesterol (25(R)-27-hydroxy Cholesterol) 是一种有效的、选择性的雌激素受体调节剂和肝X 受体激动剂。
T2967	Stigmasterol Stigmasterin,beta-Stigmasterol,豆甾醇	MMP; Endogenous Metabolite	Metabolism; Proteases/Proteasome
	Stigmasterol (Stigmasterin) 是一种植物性甾醇，具有抑制胆固醇的特性，此外在风湿性疾病的研究中被评价为抗硬化因子。
T3770	Taraxasterol 蒲公英甾醇,Taraxasterin	IL Receptor; TNF; NO Synthase; Prostaglandin Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation
	Taraxasterol (Taraxasterin) 是一种五环三萜类化合物，从Taraxacum officinale 中分离得到，具有代谢物和抗炎的活性。
T4923	7-Dehydrocholesterol Provitamin D3,7-DHC,7-去氢胆固醇	Endogenous Metabolite	Metabolism
	7-Dehydrocholesterol (Provitamin D3) 是合成胆固醇和维生素 D3的前体。7-Dehydrocholesterol 下调培养的 Smith-Lemi-Opitz 综合征皮肤成纤维细胞中的胆固醇生物合成。
TN2810	22-Dehydroclerosterol glucoside	Others	Others
	22-Dehydroclerosterol, and cholesterol are sterol constituents.
T72962	Sycosterol A
	Sycosterol A 是一种α-synuclein(α-syn)甾醇抑制剂。
T29329	24-Methylenecholesterol 24Methylenecholesterol,24 Methylenecholesterol,Chalinasterol,24-亚甲基胆固醇,Ostreasterol	Acyltransferase	Metabolism
	24-Methylenecholesterol (24 Methylenecholesterol) 是一种天然海洋甾醇，可刺激人类巨噬细胞中的胆固醇酰基转移酶 (ACAT))。
T83520	(S)-Campesterol 5-Ergosten-3β-ol
	(S)-Campesterol (5-Ergosten-3β-ol)，一种植物甾醇，存在于多种食物和植物源中，对人体健康具有潜在益处。
TN1523	Conicasterol	Others	Others
	Conicasterol displays marked cytotoxic activity against human breast adenocarcinoma cell line (MCF-7) with the IC50 value of 6.23 ug/mL.
TN4247	Ikshusterol 3-O-glucoside	Phospholipase	Metabolism
	Ikshusterol 3-O-glucoside has a potent snake-venom neutralizing capacity and it might be a potential molecule for the therapeutic treatment for snakebites.
TN5288	Ergosterol peroxide glucoside 过氧化麦角甾醇葡萄糖苷,Ergosterol peroxide 3-O-β-D-glucopyranoside
	Ergosterol peroxide exhibits anti-cancer, amoebicidal, anticomplementary, antibacterial, antiviral, anti-oxdiant, and anti-melanogenic activities. Ergosterol peroxide could as an anti-atherosclerosis agent, it exhibits hACAT-1 and Lp-PLA2 inhibitory effec
TN3814	Delta 5-avenasterol	Others	Others
	Delta 5-avenasterol has antioxidant activity.
TN4837	Pseudotaraxasterol	AChR	Neuroscience
	Pseudotaraxasterol shows cytotoxic activity against MOLT-4 cells.
TN1450	Brassicasterol 菜籽甾醇,油菜	Others	Others
	Brassicasterol may be a relevant additional biomarker in Alzheimer's disease (AD).
T14063	7α,25-Dihydroxycholesterol 7α,25-OHC	EBI2/GPR183; Endogenous Metabolite	GPCR/G Protein; Metabolism
	7α,25-Dihydroxycholesterol 是一种孤儿 GPCR 受体EBI2 (GPR183)的内源性配体和有效选择性激动剂。它对激活 EBI2 有很强的作用 (EC50=140 pM;Kd=450 pM)。它能够作为一种趋化因子，指导 B 细胞、T 细胞和树突状细胞的迁移。
T75515	7β,25-Dihydroxycholesterol
	7β,25-Dihydroxycholesterol 是一种内源性代谢物，被发现作为表达 EBI2 的免疫细胞的趋化剂。
TN1338	7Beta-Hydroxycholesterol	LDL; Calcium Channel; MAPK	MAPK; Membrane transporter/Ion channel; Metabolism
	7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells.
TN3984	Ergosterol glucoside	Others	Others
	Ergosterol glucoside is a natural product from Rehmannia glutinosa.
T73808	Zymosterol
	Zymosterol 是一种胆固醇Cholesterol 生物合成代谢物。Zymosterol 是胆固醇的前体，主要存在于质膜中。Zymosterol 在细胞内循环。
TN3248	7-Oxo-beta-sitosterol	Others	Others
	7-Oxo-beta-sitosterol是一种天然产物，属于茜草科红芽大戟属，其产品编号为 TN3248，CAS号为 2034-74-4。7-Oxo-beta-sitosterol可用作对照参考。
T38036	Lumisterol
	Lumisterol (9β,10α-Ergosterol), a steroid compound, is the (9β,10α)-stereoisomer of Ergosterol. Lumisterol is a photoprotective agent against UVB-induced DNA damage and anti-proliferative activities[1]. [1]. Anyamanee Chaiprasongsuk, et al. Protective Effects of Novel Derivatives of Vitamin D 3 and Lumisterol Against UVB-induced Damage in Human Keratinocytes Involve Activation of Nrf2 and p53 Defense Mechanisms. Redox Biol. 2019 Jun;24:101206.
TN4248	Ikshusterol	Others	Others
	Ikshusterol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4248，CAS号为 34427-61-7。
TN5947	3-Dehydro-15-deoxoeucosterol 17,23-Epoxy-29-hydroxy-27-norlanost-8-ene-3,24-dione
	3-Dehydro-15-deoxoeucosterol is a natural product from Scilla scilloides.
T41052	24,25-Dihydrolanosterol Lanostenol,二氢羊毛甾醇
	24,25-Dihydrolanosterol (Lanostenol) is a chemical compound found in the seeds of the red pepper (Capsicum annuum).
TN5292	6-O-Methylcerevisterol
	6-O-Methylcerevisterol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5292，CAS号为 126060-09-1。
T19164	8-Dehydrocholesterol	Others	Others
	8-Dehydrocholesterol is a compound whose elevated concentration is a diagnostic biochemical hallmark of classical Smith-Lemli-Opitz syndrome.
TMA0984	Cerevisterol	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Cerevisterol 是一种细胞毒性类固醇，提取于Agaricus blazei 子实体，对 DNA 聚合酶 α 的活性具有抑制作用。
T10805	Cholesterol glucuronide	Others	Others
	Cholesterol glucuronide is an endogenous metabolite of lipid generated by UDP glucuonyltransferase in the liver.
TMA1799	alpha-Spinasterol glucoside	Others	Others
	alpha-Spinasterol glucoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TMA1799，CAS号为 1745-36-4。
TN2809	22-Dehydroclerosterol	Antifection	Microbiology/Virology
	22-Dehydroclerosterol has antibacterial activity against against E. coli, S. aureus, and H. pylori.
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天然产物

Dihydrolanosterol

Cat.No: TN6736

Synonym: 24,25-Dihydrolanosterol,Lanostenol,二氢羊毛甾醇

Target: Others

25-Hydroxycholesterol

Cat.No: T4717

Synonym: 25-羟基胆固醇,25-羟基胆甾醇

Target: Others, Endogenous Metabolite, HMG-CoA Reductase

Cat.No: T4S2157

Synonym: 菜油甾醇,(24R)-5-Ergosten-3β-ol

Target: Endogenous Metabolite

Cat.No: T0760

Synonym: Cholesterin,Cholesteryl alcohol,胆固醇

Target: Estrogen Receptor/ERR, MRP, Endogenous Metabolite, ROR

Cat.No: T4970

Synonym: 羊毛甾醇,3β-Hydroxy-8,24-lanostadiene,8,24-Lanostadien-3β-ol

Target: Endogenous Metabolite

24-Hydroxycholesterol

Cat.No: T10086

Synonym: Cholest-5-ene-3beta,24-diol

Target: Liver X Receptor, NMDAR

Cat.No: T15720

Target: Endogenous Metabolite

5,6-Epoxyergosterol

Cat.No: TN7127

Target: Others

Beta-Sitosterol

Cat.No: T2966

Synonym: Cupreol,谷甾醇,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,beta-谷甾醇,22,23-Dihydrostigmasterol,Betaprost

Target: Apoptosis, Lipase, Endogenous Metabolite

Cholesterol myristate

Cat.No: T8040

Synonym: 胆甾烯基豆蔻酸酯,Cholesteryl myristate,胆固醇肉豆蔻酸,Cholesteryl tetradecanoate

Target: Others, Potassium Channel, GABA Receptor, Endogenous Metabolite, AChR

7α-Hydroxycholesterol

Cat.No: T19161

Target: Others

Cat.No: T8184

Synonym: 岩皂甾醇,岩藻甾醇

Target: PARP, Endogenous Metabolite, PPAR

Cat.No: TN1377

Synonym: Α-波菜甾醇,alpha-Spinasterol,菠甾醇

Target: COX, Antibacterial, TRP/TRPV Channel

7-Ketocholesterol

Cat.No: TN6715

Target: Others

Cat.No: T19711

Synonym: Desmesterol,24-Dehydrocholesterol

Target: Endogenous Metabolite

beta-Sitosterol acetate

Cat.No: TC0027

Target: Others

Cat.No: T3871

Synonym: Alexandrin,Sitogluside,β-Sitosterol β-D-glucoside,Eleutheroside A,西托糖苷

Target: Glucosidase

Ergosterol Acetate

Cat.No: TN7071

Synonym: Ergosta-5,7,22-trien-3-beta-yl acetate

Target: Others

Cat.No: T2912

Synonym: 麦角固醇,Provitamin D,Ergosterin,Provitamin D2

Target: Others, Endogenous Metabolite

20(S)-Hydroxycholesterol

Cat.No: T10085

Synonym: 20α-Hydroxycholesterol

Target: Smo

27-Hydroxycholesterol

Cat.No: TQ0274

Synonym: 27-羟基胆固醇,5,25R-胆甾烯-3BETA,26-二醇,25(R)-27-hydroxy Cholesterol

Target: Estrogen/progestogen Receptor, Liver X Receptor

Cat.No: T2967

Synonym: Stigmasterin,beta-Stigmasterol,豆甾醇

Target: MMP, Endogenous Metabolite

Cat.No: T3770

Synonym: 蒲公英甾醇,Taraxasterin

Target: IL Receptor, TNF, NO Synthase, Prostaglandin Receptor

7-Dehydrocholesterol

Cat.No: T4923

Synonym: Provitamin D3,7-DHC,7-去氢胆固醇

Target: Endogenous Metabolite

22-Dehydroclerosterol glucoside

Cat.No: TN2810

Target: Others

Cat.No: T72962

24-Methylenecholesterol

Cat.No: T29329

Synonym: 24Methylenecholesterol,24 Methylenecholesterol,Chalinasterol,24-亚甲基胆固醇,Ostreasterol

Target: Acyltransferase

(S)-Campesterol

Cat.No: T83520

Synonym: 5-Ergosten-3β-ol

Cat.No: TN1523

Target: Others

Ikshusterol 3-O-glucoside

Cat.No: TN4247

Target: Phospholipase

Ergosterol peroxide glucoside

Cat.No: TN5288

Synonym: 过氧化麦角甾醇葡萄糖苷,Ergosterol peroxide 3-O-β-D-glucopyranoside

Delta 5-avenasterol

Cat.No: TN3814

Target: Others

Pseudotaraxasterol

Cat.No: TN4837

Target: AChR

Cat.No: TN1450

Synonym: 菜籽甾醇,油菜

Target: Others

7α,25-Dihydroxycholesterol

Cat.No: T14063

Synonym: 7α,25-OHC

Target: EBI2/GPR183, Endogenous Metabolite

7β,25-Dihydroxycholesterol

Cat.No: T75515

7Beta-Hydroxycholesterol

Cat.No: TN1338

Target: LDL, Calcium Channel, MAPK

Ergosterol glucoside

Cat.No: TN3984

Target: Others

Cat.No: T73808

7-Oxo-beta-sitosterol

Cat.No: TN3248

Target: Others

Cat.No: T38036

Cat.No: TN4248

Target: Others

3-Dehydro-15-deoxoeucosterol

Cat.No: TN5947

Synonym: 17,23-Epoxy-29-hydroxy-27-norlanost-8-ene-3,24-dione

24,25-Dihydrolanosterol

Cat.No: T41052

Synonym: Lanostenol,二氢羊毛甾醇

6-O-Methylcerevisterol

Cat.No: TN5292

8-Dehydrocholesterol

Cat.No: T19164

Target: Others

Cat.No: TMA0984

Target: DNA/RNA Synthesis

Cholesterol glucuronide

Cat.No: T10805

Target: Others

alpha-Spinasterol glucoside

Cat.No: TMA1799

Target: Others

22-Dehydroclerosterol

Cat.No: TN2809

Target: Antifection

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