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44

抑制剂 & 化合物

24

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T82372	Free radical scavenger 1
	Free radical scavenger 1 (compound 8) 显示出对DPPH自由基的清除能力，其半数抑制浓度（IC50）为43.39 μg/ml。
T8408	GKT136901 AK120765	NADPH-oxidase; NADPH	Immunology/Inflammation; Metabolism
	GKT136901 (AK120765) 是选择性的和具有口服活性的 NADPH 氧化酶 NOX-1/4抑制剂，Ki 分别为 160 和 165 nM。它具有抗炎症活性。它也是一种选择性和直接的过氧亚硝酸清除剂。它可用于糖尿病肾病，中风和神经退行性疾病的研究。
T7717	Sodium 2-oxopropanoate Sodium pyruvate,丙酮酸钠	Reactive Oxygen Species; Endogenous Metabolite	Immunology/Inflammation; Metabolism; NF-κB
	Sodium 2-oxopropanoate (Sodium pyruvate) 是 pyruvate 的钠盐形式。pyruvate 是葡萄糖的三碳代谢物，是一种在糖酵解途径中产生的化合物，它是一种能够清除 ROS 的自由基清除剂。
T14667	BLT-1	Others; HCV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	BLT-1 是一种氨基硫脲铜螯合剂，是一种选择性清除受体 B1 型 (SR-BI) 抑制剂，抑制高密度脂蛋白 (HDL) 和 SR-BI 介导的细胞之间的脂质转移。
T36512	PTIO	NO Synthase	Immunology/Inflammation
	PTIO 是一种特定的 NO 清除剂。 PTIO 与一氧化氮反应形成二氧化氮和相应的亚氨基氮氧化物。 PTIO 可用于检查一氧化氮合酶抑制活性。
T23046	N-tert-butyl-α-Phenylnitrone (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide,N-叔丁基-α-苯基硝酮	ROS; COX	Immunology/Inflammation; Neuroscience
	N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) 是基于硝酮的自由基清除剂，可形成一氧化氮自旋加合物。它可以穿透血脑屏障，抑制 COX2的催化活性，有 ROS 清除、抗炎、神经保护、抗衰老和抗糖尿病的作用。
T0630	Ethyleneurea Imidazolidinone,2-咪唑烷酮	Others	Others
	Ethyleneurea (Imidazolidinone) 用作formaldehyde scavenger 和中间体。
T24134	HDL376 SDZ-HDL376,SDZHDL376,HDL 376,SDZ HDL376,HDL-376	Others	Others
	HDL376 (SDZ HDL376) 是一种清道夫受体 BI 抑制剂。
T6699	Tempol TMPN,Tanol,4-Hydroxy-TEMPO,阻聚剂701	Reactive Oxygen Species; ROS; Autophagy	Autophagy; Immunology/Inflammation; Metabolism; NF-κB
	Tempol (Tanol) 是一种超氧化物歧化酶类似物，可有效中和活性氧，具有抗炎、神经保护和镇痛作用。
T6606	Nicaraven	Others	Others
	Nicaraven 是新型的、化学合成的羟基自由基清除剂。
T15603	ITX5061 ITX-5061	HCV Protease; p38 MAPK	MAPK; Microbiology/Virology; Proteases/Proteasome
	ITX5061 是 p38 MAPK 的 II 型抑制剂和清道夫受体 B1（SRB1）拮抗剂，可用于研究丙型肝炎病毒感染。
T0407	Edaravone 依达拉奉右莰醇,依达拉奉,MCI-186	Apoptosis; MMP; Free radical scavengers	Apoptosis; oxidation-reduction; Proteases/Proteasome
	Edaravone (MCI-186) 是一种新型自由基清除剂，能够抑制大鼠与 MMP-9有关的脑出血。
T9442	4-Chloro-3-nitrobenzoic acid	Others	Others
	4-Chloro-3-nitrobenzoic acid 是一氧化氮清除剂，已被用于研究一氧化氮对心血管系统的影响，以及一氧化氮对免疫系统的影响。
T15393	Glycerol phenylbutyrate 苯丁酸甘油酯,HPN-100	Sigma receptor	GPCR/G Protein
	Glycerol phenylbutyrate (HPN-100) 是一种氨清除剂，也是 sigma-2 受体配体，pKi 为8.02。
T1344	4-Chloro-4'-hydroxybenzophenone	Others	Others
	4-Chloro-4'-hydroxybenzophenone 可抑制酪氨酸酶，也可作为自由基清除剂或抗氧化剂，减少脂质和蛋白质的氧化。
T19032	Nitro blue tetrazolium chloride NBT,氯化硝基四氮唑兰	NO Synthase	Immunology/Inflammation
	Nitro blue tetrazolium chloride (NBT) 是一种脱氢酶底物，能够与碱性磷酸酶底物 BCIP 一起用于 western blotting 和免疫组化染色。
T36506	Tempone 4-Oxo-tempo
	Tempone 是一种氨基氧烷，具有自由基清除剂的作用，会与活性氧（ROS）发生反应。静脉注射 Tempone 可降低自发性高血压大鼠的平均动脉。
T5363	Tempo 2,2,6,6-四甲基哌啶氧化物,2,2,6,6-Tetramethylpiperidinooxy	Free radical scavengers; Reactive Oxygen Species; DNA/RNA Synthesis; Mitochondrial Metabolism	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
	Tempo (2,2,6,6-Tetramethylpiperidinooxy) 可用作自由基清除剂、有机合成中的试剂和电子自旋共振光谱中的结构探针。它可在催化循环中使超氧化物歧化，也可诱导DNA 链断裂。
T38164	MnTBAP chloride Mn(III)TBAP
	MnTBAP chloride (Mn(III)TBAP) 是一种具有细胞渗透性的超氧化物歧化酶 (SOD) 模拟物和过氧亚硝酸盐清除剂，能使SOD-大肠杆菌的加倍时间减少了2倍。 MnTBAP chloride 通过上调 BMPR-II 和抑制 NFκB 信号传导展现抗炎作用。MnTBAP chloride 是一种锰卟啉配合物，具有抗氧化性能，具有用于研究慢性肾脏疾病 (CKDs) 纤维化反应的潜力。
T21967	MEG hemisulfate Mercaptoethylguanidine hemisulfate	NOS	Immunology/Inflammation
	MEG hemisulfate (Mercaptoethylguanidine hemisulfate) 是一种有效和选择性的诱导型 NO 合酶 (iNOS) 的抑制剂，在组织匀浆中抑制 iNOS，ecNOS 和 bNOS 的 EC50 值分别为 11.5，110 和 60 μM。MEG hemisulfate 也有效的过氧亚硝酸盐清除剂，可抑制过氧亚硝酸盐诱导的氧化过程。MEG hemisulfate 在许多炎症实验模型中具有保护作用，包括缺血/再灌注损伤，牙周炎，失血性休克，炎性肠病以及内毒素和败血性休克。
T9948	NecroX-7 LC-280126,LC28-0126,LC28 0126	NADPH-oxidase	Immunology/Inflammation
	NecroX-7 (LC-280126) 是一种有效的自由基清除剂和 HMGB1(高迁移率族蛋白 1) 抑制剂。NecroX-7 可以作为对乙酰氨基酚毒性的解毒剂。NecroX-7 通过抑制缺血/再灌注损伤中 HMGB1 的释放发挥保护作用。NecroX-7 抑制 HMGB1 诱导的 TNF 和 IL-6的释放，以及TLR-4和晚期糖基化终产物受体的表达，用于移植物抗宿主病 (GVHD) 研究。
T28222	5-Hydroxy-1-methylhydantoin HD-003,HD003,5-羟基-1-甲基咪唑啉-2,4-二酮,NZ419,NZ-419,HD 003,NZ 419	Bradykinin Receptor	GPCR/G Protein
	5-Hydroxy-1-methylhydantoin (HD-003) 是一种可能用于治疗肾衰竭的抗氧化剂。它是肌酐代谢物，是一种羟基自由基清除剂，此前已显示通过抑制大鼠慢性肾病的进展来提供肾脏保护。它是一种新型抗氧化药物，可完全抑制 B2-激肽受体(B2KR) 对 VSMC 中高葡萄糖 (25 mM) 刺激的反应，并且还显示可减弱 BK 对 VSMC 重塑的影响。它抑制 BK 诱导的 MAPK 磷酸化增加并减弱 VSMC 中结缔组织生长因子 (CTGF) 蛋白水平的增加。这些研究结果表明，它可能通过其抗氧化特性赋予血管保护免受高葡萄糖浓度和 BK 刺激以改善血管损伤和重塑。
T26837	BLT-3 BLT 3
	BLT-3 is a novel scavenger receptor BI (SR-BI) inhibitor.
T23853	Carazostatin
	Carazostatin is an antioxidant, free radical scavenger, and potent lipid peroxidation inhibitor.
T35974	5-methyl-2-HOBA (hydrochloride)
	5-methyl-2-HOBA is an isoketal scavenger. It reduces angiotensin II-induced increases in systolic blood pressure in mice.
T10253	AD 0261	Others	Others
	AD 0261 is a radical scavenger. It has a strong inhibitory action on the generation of lipid peroxides and superoxide anions.
T11152	Edaravone-d5 MCI-186 D5	Others	Others
	Edaravone, a novel and potent free radical scavenger, effectively prevents MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Its deuterium-labeled variant, Edaravone D5, retains the original compound's attributes while offering isotopic labeling benefits.
T60530	Mercaptoethylguanidine (MEG) (dihydrobromide)
	Mercaptoethylguanidine (MEG) dihydrobromide 是选择性的诱导型一氧化氮合酶抑制剂和过氧亚硝酸盐清除剂，在炎症性肠病研究中具有潜力。
T80720	Zovostotug
	Zovostotug为针对人类CD163（又称1型富含半胱氨酸结构域的清道夫受体M130）的单克隆抗体。
T38945	Carboxy-PTIO
	Carboxy-PTIO is a highly effective nitric oxide (NO) scavenger known for its rapid reaction rate with NO, resulting in the formation of nitric dioxide (NO2). Its direct scavenging action against NO plays a crucial role in preventing hypotension and endotoxic shock, particularly in lipopolysaccharide-stimulated rat models.
T40979	XJB-5-131
	XJB-5-131 is a synthetic, bi-functional antioxidant specifically designed to target mitochondria for the scavenging of reactive oxygen species (ROS) and electrons, thereby acting as a radical scavenger. Additionally, it serves as an effective protector and mitigator against ionizing irradiation for cord blood mononuclear cells (CB MNCs).
T25943	Phenazoviridin
	Phenazoviridin 是一种新发现的微生物自由基清除剂，从链霉菌 HR04的培养基中分离得到。它是一种抗低氧化合物，对大鼠脑匀浆中的脂质过氧化具有较强的抑制活性，对小鼠具有抗缺氧活性。
T41058	Nelonemdaz potassium Neu2000potassium,Salfaprodil
	Nelonemdaz potassium (also known as Salfaprodil) is a potent NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). This compound exhibits remarkable neuroprotection against cell death induced by both NMDA and free radicals, in addition to its role as a free radical scavenger.
T35967	N-methyl-2-HOBA (hydrochloride)
	N-methyl-2-HOBA is a methylated form of the isoketal scavenger 2-HOBA .1It has low reactivity with isoketals and has no effect on hypertension induced by angiotensin II . N-methyl-2-HOBA has been used as a negative control for the activity of 2-HOBA in a mouse model of hypertension. 1.Kirabo, A., Fontana, V., de Faria, A.P.C., et al.DC isoketal-modified proteins activate T cells and promote hypertensionJ. Clin. Invest.124(10)4642-4656(2014)
T60238	Acloproxalap
	Acloproxalap 是一种基于喹啉的醛清除剂，可用于研究有毒醛积累的疾病，如眼部、皮肤等炎症性疾病，肺炎等呼吸系统疾病，器官疾病以及病毒感染相关性综合症等。
T36556	(±)5(6)-DiHET lactone
	5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET. In solution, 5(6)-EET degrades into 5(6)-DiHET and 5(6)-δ-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS. 5,6-DiHET potently induces vasodilation of isolated canine coronary arterioles, with 41 and 100% inhibition occurring at 0.01 and 100 pM, respectively. It also induces vasodilation in isolated human microvessels and increases intracellular calcium levels in a dose-dependent manner, an effect that can be b...
T80880	Valziflocept BAX1810,TAK-752
	Valziflocept (BAX1810; TAK-752)是一种靶向Fc和FcγR的重组可溶性人FcγRIIb受体。该受体通过结合并中和致病IgG发挥作用，充当“诱饵”或“清道夫”，从而有助于缓解自身免疫性疾病如系统性红斑狼疮（SLE）的病情。
T36172	KOdiA-PC
	Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl) phosphatidylcholine, or KOdiA-PC, is one of the most potent CD36 ligands among the oxLDL species. KOdiA-PC confers CD36 scave...
T36171	KDdiA-PC
	Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. KDdiA-PC is one of the most potent CD36 ligands among the oxLDL species. KDdiA-PC confers CD-36 scavenger receptor binding affinity to LDL at a frequency of only two...
T35580	POV-PC
	Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. 1-(Palmitoyl)-2-(5-oxovaleroyl)-phosphatidylcholine, or POV-PC, is one of the oxLDL species derived from 2-arachidonoyl or eicosapentanoyl phospholipids. POV-PC conf...
T83922	Pep2 Peptide
	Pep2 peptide是一种针对跨膜糖蛋白CD36的肽配体，CD36也被称为清道夫受体B2。在1 mM浓度使用时，Pep2 peptide在无细胞检测中选择性地与CD36结合，相比于人血清白蛋白(HSA)、IgG和CD44具有更高的亲和力。与不含Pep2 peptide的胶束相比，包裹抗癌剂多柔比星的Pep2 peptide功能化胶束能增加多柔比星在过表达CD36的HepG2肝细胞癌细胞中的细胞内输送，并提升细胞毒性。
T83422	1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine
	1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine 是一种由磷酸甘油、胆碱和棕榈酸构成的甘油磷酸胆碱类化合物，通常在体内氧化应激位点累积。该化合物是 B 类清道夫受体 (CD36和SR-BI) 的有效配体，特别是氧化磷脂 oxPC(CD36)。此外，氧化磷脂 (oxPLs) 在肿瘤细胞凋亡中扮演关键角色，并且在恶性胆管狭窄疾病中可能会有所增加。
T83771	6-PPD Antioxidant 4020,N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine
	6-PPD是一种取代的p-苯二胺。它通过形成亚硝基自由基来清除臭氧。当6-PPD的浓度分别为0.022 mg/L和0.22 mg/L时，斑马鱼胚胎的孵化能力分别下降了25.6%和78.9%。6-PPD还会降低斑马鱼胚胎的活动能力和体长，并诱导发育畸形及氧化应激。含有6-PPD的配方已作为橡胶中的稳定剂添加物和抗臭氧剂使用。
T83709	LIH383 TFA Phe-Gly-Gly-Phe-Met-Arg-Arg-Lys-NH2
	LIH383是一种趋化因子(C-X-C motif) 受体7 (CXCR7)的多肽激动剂，属于趋化因子和阿片肽清除受体。它专一性激活CXCR7 (EC50 = 0.61 nM)，在3 µM浓度时，相比μ-、δ-、κ-阿片受体以及诺氨酸阿片肽（NOP）受体的β-arrestin招募实验中表现出高选择性。LIH383（3 µM）通过阻止U87-ACKR3细胞中，由非选择性阿片受体激动剂dynorphin A诱导的CXCR7对阿片肽的摄取，发挥作用。

化合物

Free radical scavenger 1

Cat.No: T82372

Cat.No: T8408

Synonym: AK120765

Target: NADPH-oxidase, NADPH

Sodium 2-oxopropanoate

Cat.No: T7717

Synonym: Sodium pyruvate,丙酮酸钠

Target: Reactive Oxygen Species, Endogenous Metabolite

Cat.No: T14667

Target: Others, HCV Protease

Cat.No: T36512

Target: NO Synthase

N-tert-butyl-α-Phenylnitrone

Cat.No: T23046

Synonym: (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide,N-叔丁基-α-苯基硝酮

Target: ROS, COX

Cat.No: T0630

Synonym: Imidazolidinone,2-咪唑烷酮

Target: Others

Cat.No: T24134

Synonym: SDZ-HDL376,SDZHDL376,HDL 376,SDZ HDL376,HDL-376

Target: Others

Cat.No: T6699

Synonym: TMPN,Tanol,4-Hydroxy-TEMPO,阻聚剂701

Target: Reactive Oxygen Species, ROS, Autophagy

Cat.No: T6606

Target: Others

Cat.No: T15603

Synonym: ITX-5061

Target: HCV Protease, p38 MAPK

Cat.No: T0407

Synonym: 依达拉奉右莰醇,依达拉奉,MCI-186

Target: Apoptosis, MMP, Free radical scavengers

4-Chloro-3-nitrobenzoic acid

Cat.No: T9442

Target: Others

Glycerol phenylbutyrate

Cat.No: T15393

Synonym: 苯丁酸甘油酯,HPN-100

Target: Sigma receptor

4-Chloro-4'-hydroxybenzophenone

Cat.No: T1344

Target: Others

Nitro blue tetrazolium chloride

Cat.No: T19032

Synonym: NBT,氯化硝基四氮唑兰

Target: NO Synthase

Cat.No: T36506

Synonym: 4-Oxo-tempo

Cat.No: T5363

Synonym: 2,2,6,6-四甲基哌啶氧化物,2,2,6,6-Tetramethylpiperidinooxy

Target: Free radical scavengers, Reactive Oxygen Species, DNA/RNA Synthesis, Mitochondrial Metabolism

MnTBAP chloride

Cat.No: T38164

Synonym: Mn(III)TBAP

MEG hemisulfate

Cat.No: T21967

Synonym: Mercaptoethylguanidine hemisulfate

Target: NOS

Cat.No: T9948

Synonym: LC-280126,LC28-0126,LC28 0126

Target: NADPH-oxidase

5-Hydroxy-1-methylhydantoin

Cat.No: T28222

Synonym: HD-003,HD003,5-羟基-1-甲基咪唑啉-2,4-二酮,NZ419,NZ-419,HD 003,NZ 419

Target: Bradykinin Receptor

Cat.No: T26837

Synonym: BLT 3

Cat.No: T23853

5-methyl-2-HOBA (hydrochloride)

Cat.No: T35974

Cat.No: T10253

Target: Others

Cat.No: T11152

Synonym: MCI-186 D5

Target: Others

Mercaptoethylguanidine (MEG) (dihydrobromide)

Cat.No: T60530

Cat.No: T80720

Cat.No: T38945

Cat.No: T40979

Cat.No: T25943

Nelonemdaz potassium

Cat.No: T41058

Synonym: Neu2000potassium,Salfaprodil

N-methyl-2-HOBA (hydrochloride)

Cat.No: T35967

Cat.No: T60238

(±)5(6)-DiHET lactone

Cat.No: T36556

Cat.No: T80880

Synonym: BAX1810,TAK-752

Cat.No: T36172

Cat.No: T36171

Cat.No: T35580

Cat.No: T83922

1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine

Cat.No: T83422

Cat.No: T83771

Synonym: Antioxidant 4020,N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine

Cat.No: T83709

Synonym: Phe-Gly-Gly-Phe-Met-Arg-Arg-Lys-NH2

Cat. No.	Product Name	Target	Signaling Pathways
TN1058	Pelargonidin chloride	NOS; Reactive Oxygen Species; Nrf2; NO Synthase	Immunology/Inflammation; Metabolism; NF-κB
	Pelargonidin chloride 是一种氧化氮自由基的清除剂，具有抗氧化作用。
TN1621	Eriodictyol-7-O-glucoside	Nrf2	Immunology/Inflammation
	Eriodictyol-7-O-glucoside 是一种 Nrf2 激活剂，可防止顺铂诱导的毒性。 Eriodictyol-7-O-glucoside 是一种类黄酮和自由基清除剂，在开心果皮中具有抗氧化活性。
T41358	2-Hydroxybenzylamine	Others	Others
	2-Hydroxybenzylamine 是一种有效的 IsoLG 小分子清除剂，可将活性物质作为惰性加合物螯合。 2-Hydroxybenzylamine 可用于通过减少具有天然生物分子的 IsoLG 加合物来减少心房颤动消融后心房颤动和其他心房心律失常的早期复发。
T3S1068	Oxyresveratrol trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,氧化白藜芦醇,Tetrahydroxystilbene	Tyrosinase; Autophagy; HSV	Autophagy; Microbiology/Virology; Proteases/Proteasome
	Oxyresveratrol (trans-Oxyresveratrol) 是非竞争性酪氨酸酶抑制剂，对蘑菇酪氨酸酶的 IC50值为 1.2 µM。它抑制HSV-1，HSV-2和水痘带状疱疹病毒，具有神经保护作用。它是天然抗氧化剂和自由基清除剂。
T1648	α-Vitamin E 天然维生素E,Dexrabeprazole Sodium,Vitamin E,Alpha-Tocopherol,D-α-Tocopherol,5,7,8-Trimethyltocol,D-α-生育酚,(+)-alpha-Tocopherol	Others; Ferroptosis; Influenza Virus; Reactive Oxygen Species; Endogenous Metabolite; Antibacterial; PKC; GST	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Others; oxidation-reduction
	α-Vitamin E (Dexrabeprazole Sodium) 是一种天然存在的维生素 E，也是抗氧化剂。
T8059	N-Acetyl-L-methionine N-Acetylmethionine,N-乙酰-L-蛋氨酸	Others; Endogenous Metabolite	Metabolism; Others
	N-Acetyl-L-methionine (N-Acetylmethionine) 是人体代谢物，在营养和代谢作用上和 L-methionine 相当。其中 L-methionine 是生长发育并不能够少的氨基酸。
TN2100	Pratensein 红车轴草素,三叶草	Others; NF-κB	NF-κB; Others
	Pratensein 是黄酮类化合物，能够减少氧化损伤和恢复突触和 BDNF 水平，改善 β-淀粉样蛋白诱导的大鼠认知障碍。
T2778	(+)-Catechin Hydrate 一水合儿茶素,(+)-水合儿茶素	Antioxidant; COX	Immunology/Inflammation; Neuroscience; oxidation-reduction
	(+)-Catechin hydrate 是来自茶树的抗氧化类黄酮，可抑制环加氧酶-1，IC50为 1.4 μM。它是一种自由基清除剂，可防止多种生物系统中自由基介导的损害。
T2838	Naringenin 柚皮素,Naringetol,S-Dihydrogenistein,Pelargidanon,Salipurol,NSC 11855,NSC 34875	P450; Influenza Virus; Reactive Oxygen Species; Endogenous Metabolite; PPAR	DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Naringenin (NSC-11855) 是葡萄柚中主要的黄烷酮，可作为抗氧化剂、自由基清除剂、抗炎剂、碳水化合物代谢促进剂、免疫系统调节剂。
T40080	(±)-Taxifolin (±)-Dihydroquercetin	Antioxidant; Tyrosinase	oxidation-reduction; Proteases/Proteasome
	(±)-Taxifolin ((±)-Dihydroquercetin) 是 Taxifolin 的外消旋体。Taxifolin 是一种常见于洋葱，水飞蓟，法国海洋松树皮和道格拉斯冷杉树皮中的类黄酮，具有抗酪氨酸酶和抗纤维化活性。Taxifolin 对胶原酶具有抑制作用，IC 50 值为 193.3 μM。Taxifolin是一种具有抗氧化能力的自由基清除剂。
T40615	N,N'-Dimethylthiourea N,N-二甲基硫脲,DMTU	Antioxidant	oxidation-reduction
	N,N'-Dimethylthiourea (DMTU) 是一种分离自黑蒜的化合物。N,N'-Dimethylthiourea 具有口服活性的羟基自由基 (•OH) 的清除剂，通过活化的中性粒细胞在体外阻止 •OH 的产生。N,N'-Dimethylthiourea 通过发挥 •OH 清除和抗炎作用，防止水浸限制应激诱导的大鼠胃粘膜损伤。
T26288	Clovamide trans-Clovamide,N-trans-Caffeoy-L-dopa	Apoptosis; Influenza Virus; ROS; Antibacterial	Apoptosis; Immunology/Inflammation; Microbiology/Virology
	Clovamide (trans-Clovamide) 是一种天然存在的咖啡酰结合物，具有抗菌、抗炎、抗氧化和神经保护作用。它是一种极好的活性氧和氧自由基清除剂。
T3753	Sinapinic Acid Sinapic acid,芥子酸,Synapoic acid	Apoptosis; RAAS; Reactive Oxygen Species; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB
	Sinapinic Acid (Synapoic acid) 是从 Hydnophytum formicarumJack. 根中分离到的酚类，是HDAC 抑制剂，对ACE-I 的活性也有抑制作用。它有抗肿瘤活性，诱导肿瘤细胞凋亡，具有抗氧化、抗糖尿病的作用。
TN4609	Myzodendrone	Others	Others
	Myzodendrone is a highly effective as free radical scavenger.
T39393	Samwirin A
	Samwirin A is a promising radical scavenger in aqueous media at physiological pH.
T8518	Erigeside I	Others	Others
	Erigeside I is a radical scavenger.
T4131	Arjunic acid	COX; Antifection	Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Arjunic acid is a strong antioxidant and a free radical scavenger. Arjunic acid shows activity against Gram-positive and Gram-negative bacteria with MIC values ranging between 1.9 and 15.6 microg/mL.
TN4420	Latifolin 檀木	IL Receptor; IκB/IKK; TNF; NOS; NF-κB; COX; Nrf2; Prostaglandin Receptor; Antifection; Autophagy	Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB
	Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-ÎºB activation via Nrf2-mediated heme oxygenase-1 expression. Latifolin displays potent anticarcinogenic phase II marker enzyme, quinone reductase (QR) inducing activity and high chemopreventive indices. Latifolin also shows antifungal activity against white- and brown-rot fungi.
T38497	(-)-Taxifolin (-)-二氢槲皮素,(-)-Dihydroquercetin
	(-)-Taxifolin is the less active enantiomer of Taxifolin, demonstrating vital anti-tyrosinase activity and notable inhibition against collagenase (IC50 = 193.3 μM). It is valued as an essential natural compound showing antifibrotic potential, while also acting as a capable free radical scavenger and possessing antioxidant capacity.
T72806	Isobellidifolin 异雏菊叶龙胆酮
	Isobellidifolin，一种蒽酮类化合物，同时兼具自由基清除剂和抗氧化功能，亦显示出有效的抗真菌活性。
T75532	Cirsiliol 4′-glucoside
	Cirsiliol 4′-glucoside，从Ruellia tuberosaL 中提取，是一种具有抗糖尿病潜力的自由基清除剂。
TN4399	Kushenol C	SGLT; NF-κB; ROS; BACE; Antifection	GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB
	Kushenol C is a good 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenger, and it exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2). Kushenol C shows antimicrobial activity against Staphylococcus aureus and Streptococcus mutan
TN2050	Peonidin-3-O-glucoside chloride Peonidin 3-Glucoside Chloride	Free radical scavengers	oxidation-reduction
	Peonidin-3-O-glucoside chloride (Peonidin 3-Glucoside Chloride) 是一种具有自由基清除活性的花青素，可用于作为胰岛素促分泌剂的研究。
T79996	N,N′-Diferuloylputrescine	Melanocortin Receptor	GPCR/G Protein; Neuroscience
	N,N′-Diferuloylputrescine 作为pigmentation的抑制剂，有效减少了57%的色素沉着，并显著降低了MITF蛋白水平。同时，该化合物对活性氧表现出强大的抗氧化活性。

天然产物

Pelargonidin chloride

Cat.No: TN1058

Target: NOS, Reactive Oxygen Species, Nrf2, NO Synthase

Eriodictyol-7-O-glucoside

Cat.No: TN1621

Target: Nrf2

2-Hydroxybenzylamine

Cat.No: T41358

Target: Others

Cat.No: T3S1068

Synonym: trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,氧化白藜芦醇,Tetrahydroxystilbene

Target: Tyrosinase, Autophagy, HSV

Cat.No: T1648

Synonym: 天然维生素E,Dexrabeprazole Sodium,Vitamin E,Alpha-Tocopherol,D-α-Tocopherol,5,7,8-Trimethyltocol,D-α-生育酚,(+)-alpha-Tocopherol

Target: Others, Ferroptosis, Influenza Virus, Reactive Oxygen Species, Endogenous Metabolite, Antibacterial, PKC, GST

N-Acetyl-L-methionine

Cat.No: T8059

Synonym: N-Acetylmethionine,N-乙酰-L-蛋氨酸

Target: Others, Endogenous Metabolite

Cat.No: TN2100

Synonym: 红车轴草素,三叶草

Target: Others, NF-κB

(+)-Catechin Hydrate

Cat.No: T2778

Synonym: 一水合儿茶素,(+)-水合儿茶素

Target: Antioxidant, COX

Cat.No: T2838

Synonym: 柚皮素,Naringetol,S-Dihydrogenistein,Pelargidanon,Salipurol,NSC 11855,NSC 34875

Target: P450, Influenza Virus, Reactive Oxygen Species, Endogenous Metabolite, PPAR

Cat.No: T40080

Synonym: (±)-Dihydroquercetin

Target: Antioxidant, Tyrosinase

N,N'-Dimethylthiourea

Cat.No: T40615

Synonym: N,N-二甲基硫脲,DMTU

Target: Antioxidant

Cat.No: T26288

Synonym: trans-Clovamide,N-trans-Caffeoy-L-dopa

Target: Apoptosis, Influenza Virus, ROS, Antibacterial

Cat.No: T3753

Synonym: Sinapic acid,芥子酸,Synapoic acid

Target: Apoptosis, RAAS, Reactive Oxygen Species, HDAC

Cat.No: TN4609

Target: Others

Cat.No: T39393

Cat.No: T8518

Target: Others

Cat.No: T4131

Target: COX, Antifection

Cat.No: TN4420

Synonym: 檀木

Target: IL Receptor, IκB/IKK, TNF, NOS, NF-κB, COX, Nrf2, Prostaglandin Receptor, Antifection, Autophagy

Cat.No: T38497

Synonym: (-)-二氢槲皮素,(-)-Dihydroquercetin

Isobellidifolin

Cat.No: T72806

Synonym: 异雏菊叶龙胆酮

Cirsiliol 4′-glucoside

Cat.No: T75532

Cat.No: TN4399

Target: SGLT, NF-κB, ROS, BACE, Antifection

Peonidin-3-O-glucoside chloride

Cat.No: TN2050

Synonym: Peonidin 3-Glucoside Chloride

Target: Free radical scavengers

N,N′-Diferuloylputrescine

Cat.No: T79996

Target: Melanocortin Receptor

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