首页工具

登录

搜索结果

Search Results for " isoform "

136

抑制剂 & 化合物

10

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
TP2098	Echistatin Echistatin, α1 isoform
	Potent irreversible αVβ3 integrin antagonist (Ki = 0.27 nM). Disrupts attachment of osteoclasts to bone and inhibits bone reabsorption (IC50 = 0.1 nM). Prevents ADP-induced platelet aggregation via inhibition of glycoprotein IIb/IIIa (GpIIb/IIIa, αIIbβ3)
T16129	MPI_5a	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	MPI_5a 是高效的 HDAC6选择性抑制剂，IC50=36 nM，对其他 HDAC 酶几乎无抑制作用。MPI_5a 抑制细胞内酰基微管蛋白积累， IC50为 210 nM。
T76655	Prokineticin 2 Isoform 2 (human)
	Prokineticin 2 Isoform 2 (human) 为一下丘脑神经肽，能减少食物摄入，并在啮齿动物的体温调节与能量代谢中发挥作用。此外，Prokineticin 2 对高血糖、代谢综合征 (MetS) 及肥胖研究具有潜在价值。
T76064	Beta-defensin 103 isoform X1, pig
	Beta-defensin 103 isoform X1, pig 是一种抗菌肽、在多种生物体内被发现，参与了先天性免疫防线。
T76064L	Beta-defensin 103 isoform X1, pig TFA
	Beta-defensin 103 isoform X1, pig TFA 是一种抗菌肽、在多种生物体内被发现，参与了先天性免疫防线。
T12103	MR-L2	PDE	Metabolism
	MR-L2 是可逆的、非竞争性的长型异构体磷酸二酯酶 -4激活剂，可以激活代表性的 PDE4 长型异构体 (PDE4A4、PDE4B1、PDE4C3、PDE4D5)。它可抑制 PGE2- 诱导的 MDCK 细胞囊肿形成，其EC50=1.2 µM。
T6704	TG 100713 TG100713	PI3K	PI3K/Akt/mTOR signaling
	TG 100713 是一种PI3K 的抑制剂，抑制PI3Kδ，γ，α和β的IC50值分别为24、50、165 和 215 nM。
T2256	CNX-1351 1-[4-[[2-(1H-吲唑-4-基)-4-(4-吗啉基)噻吩并[3,2-D]嘧啶-6-基]甲基]-1-哌嗪基]-6-甲基-5-庚烯-1,4-二酮	PI3K	PI3K/Akt/mTOR signaling
	CNX1351 是有效的、选择性的 PI3Kα 抑制剂，其 IC50=6.8 nM。
T22774L	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)	Others	Others
	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) 是延伸因子 1 亚基。真核翻译延伸因子 1 alpha 1 (EEF1A1) 编码延伸因子 alpha 亚基的同种型- 1 复合物，负责将氨酰 tRNA 酶促递送至核糖体。这种亚型（α 1）在脑、胎盘、肺、肝、肾和胰腺中表达，另一种亚型（α 2）在脑、心脏和骨骼肌中表达。这种亚型在 66% 的 Felty 综合征患者中被鉴定为自身抗原。已发现该基因在许多染色体上具有多个拷贝，其中一些（如果不是全部）代表不同的假基因。
T14089	AC-261066 AC 261066	Retinoid Receptor	Metabolism
	AC-261066是一种口服的RARβ2的同型选择性激动剂，pEC50为8.0。
T8584	6-Phenyldihydropyrimidine-2,4(1h,3h)-dione 2,4(1H,3H)-Pyrimidinedione,dihydro-6-phenyl-	Others	Others
	6-Phenyldihydropyrimidine-2,4(1h,3h)-dione 靶向多嘧啶束结合蛋白 1 亚型 a（人）。
T3985	GDC-0326 GDC 0326,GDC0326	PI3K	PI3K/Akt/mTOR signaling
	GDC-0326是一种有效，选择性的 PI3Kα抑制剂，Ki=0.2 nM。
T14947	CHDI-390576	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	CHDI-390576 is a CNS penetrant class IIa HDAC inhibitor (IC50s: 54 nM, 60 nM, 31 nM, 50 nM for class IIa HDAC4, HDAC5, HDAC7, HDAC9). It shows >500-fold selectivity over class I HDACs (1, 2, 3) and ~150-fold selectivity over HDAC8 and the class IIb HDAC6 isoform.
T21529	(S)-Mephenytoin	Others	Others
	(S)-Mephenytoin 是一种抗惊厥剂。(S)-Mephenytoin 作为细胞色素 P450 (CYP) 同种型 CYP2C19 的底物，可用于分析细胞色素 P450 代谢。
T35501	5,6-trans-Vitamin D3 5,6-trans-Colecalciferol,5,6-trans-Cholecalciferol,Cholecalciferol EP Impurity A	Vitamin	Metabolism
	5,6-trans-Vitamin D3（5,6-trans-Cholecalciferol）是维生素 D3 的异构体，经光照后在皮肤表面由 Vitamin D3 转化而来。
T14090	AC-55649	Retinoid Receptor	Metabolism
	AC-55649是一种有效的、高度亚型选择性的人 RARβ2受体激动剂，pEC50为6.9。
T9608	KL201	Others	Others
	KL201 是一种昼夜节律调制器，是 CRY1选择性的稳定剂，对 CRY2 没有稳定作用。KL201 延长了细胞和组织中的昼夜节律周期。
T2057	BVT 2733	Dehydrogenase	Metabolism
	BVT 2733 是具有口服活性的、强效的、非甾体类11β-HSD1选择性抑制剂。它对小鼠 11β-HSD1 酶的作用 (IC50:96 nM) 比对人 11β-HSD1 酶 (IC50:3341 nM) 的作用强。它对关节炎和肥胖相关疾病具有潜在的研究价值。
T1999	Taselisib RG-7604,GDC-0032	PI3K; Carbonic Anhydrase	Metabolism; PI3K/Akt/mTOR signaling
	Taselisib (GDC-0032) 是 PI3K 抑制剂，靶向作用于突变 PI3KCA。它能够抑制 PI3Kα (IC50:0.29 nM)，PI3Kβ (IC50:0.91 nM) 和 PI3Kγ (IC50:0.97 nM)。
T2002	PF-4708671 PF4708671	S6 Kinase; Autophagy	Autophagy; MAPK; PI3K/Akt/mTOR signaling
	PF-4708671 是一种可渗透细胞的 p70 核糖体 S6 激酶抑制剂，对 S6K1的Ki 为 20 nM，IC50为 160 nM。
T2287	PIK-75 hydrochloride PIK-75 HCl,2-甲基-5-硝基苯磺酸 [(6-溴咪唑并[1,2-a]吡啶-3-基)亚甲基]甲基肼盐酸盐,PIK-75	Apoptosis; DNA-PK; PI3K	Apoptosis; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	PIK-75 hydrochloride (PIK-75 HCl) 是一种可逆的 DNA-PK 和 p110α-选择性抑制剂，抑制 DNA-PK，p110α和 p110γ，可诱导凋亡。
T8840	PF-543 hydrochloride PF-543	Apoptosis; S1P Receptor; Autophagy; LPL Receptor	Apoptosis; Autophagy; GPCR/G Protein
	PF-543 hydrochloride (PF-543) 是一种选择性可逆和鞘氨醇竞争性SPHK1抑制剂，对SPHK1的选择性是 SPHK2 的 100 倍以上。它还是全血中 1-磷酸鞘氨醇形成的有效抑制剂，诱导细胞凋亡、坏死和自噬。
T64377	AGI-41998 tautomers	Others	Others
	AGI-41998 tautomers 是pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-[(2,2,2-trifluoroethyl)amino]-. pyrido[4,3-d]pyrimidin-7(6H)-one 的互变异构体。pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-[(2,2,2-trifluoroethyl)amino]-. pyrido[4,3-d]pyrimidin-7(6H)-one 是S-adenosylmethionine synthase isoform type-2抑制剂, IC50= 0.022μM。
T16333	NKY80 Adenylyl cyclase type V Inhibitor	Adenylyl cyclase	Neuroscience
	NKY80 调节心脏和肺组织中的腺苷酸环化酶催化活性。 NKY80 是腺苷酸环化酶 V 型亚型的非竞争性抑制剂（IC50 值：V、III 和 II 型分别为 8.3 µM、132 µM 和 1.7 mM）。
T27371	FR-167356 FR167356,FR 167356	ATPase	Membrane transporter/Ion channel
	FR-167356 是 a3 异构体液泡型 H+-ATPase 的特异性抑制剂，对破骨细胞质膜、肾刷状缘膜和巨噬细胞微粒体的 IC50 分别为 170 nM、370 nM 和 220 nM。 FR-167356 减少 B16-F10 细胞的骨转移。
T21938	AS-041164	PI3K	PI3K/Akt/mTOR signaling
	AS-041164 是选择性的，具有口服活性的PI3Kγ亚型抑制剂，IC50=70 nM。它对 PI3Kα (IC50:240 μM)，PI3Kβ (IC50:1.45 μM) 和 PI3Kδ (IC50:1.70 μM) 的活性较低。它具有抗炎活性。
T9564	IRE1α kinase-IN-1	IRE1	Cell Cycle/Checkpoint
	IRE1α kinase-IN-1 是IRE1α 的选择性抑制剂(IC50为 77 nM)，对 IRE1α 的选择性高于 IRE1β 亚型 100 倍。它抑制内质网诱导的 IRE1α 寡聚和自磷酸化，并抑制 IRE1α RNase 活性 (IC50=80 nM)。
T4281	Endoxifen (E/Z)-N-desmethyl-4-hydroxy Tamoxifen,N-去甲基-4-羟基-,(E/Z)-Endoxifen	Estrogen Receptor/ERR; Aromatase; Estrogen/progestogen Receptor; Parasite; Drug Metabolite	Endocrinology/Hormones; Metabolism; Microbiology/Virology
	Endoxifen ((E/Z)-Endoxifen) 是 Tamoxifen 的关键活性代谢物，能抑制芳香酶的活性，与雌激素受体有较高的亲和力和特异性。它有潜力研究乳腺癌。
T27787L	L-797,591 hydrochloride L-797,591 hydrochloride(217480-24-5 Free base)
	L-797,591 hydrochloride 对生长抑素受体亚型 1 (SSTR1)有活性。L-797,591 hydrochloride 常与 AG1478 联合使用来增强表达 SSTR1的细胞中 p-ERK5的表达。L-797,591 hydrochloride 在共转染的细胞中显著增强了 p38的磷酸化，这一作用在与 AG1478联合处理时被逆转。
T24873	TGX-115 TGX 115	PI3K	PI3K/Akt/mTOR signaling
	TGX-115是一种细胞渗透性和有效的PI 3-K 异构体p110β/p110δ抑制剂(对p110β IC50值为 0.13 μM, 对p110δ值为0.63 μM），是一种调节血小板粘附过程的酶，可抑制磷酸肌苷（PI）3-激酶，可用来治疗冠状动脉闭塞、中风、急性冠状动脉综合征、急性心肌梗塞、血管再狭窄、动脉硬化和不稳定心绞痛等心血管疾病。
T8944	TTA-A2	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	TTA-A2 是一种选择性 T 型钙通道拮抗剂，是一种有效的抗惊厥药，可减少孕烷 X 受体的激活。它对 Cav3.1 (a1G) 和 Cav3.2 (a1H) 通道在 -80 mV 和- 100 mV 保持电位上具有同样的作用，IC50 值分别为 89 和 92 nM。它可用于多种人类神经系统疾病的研究，包括睡眠障碍和癫痫。
T36696	DMBA
	7,12-Dimethylbenz[a]anthracene (DMBA) is a polycyclic aromatic hydrocarbon (PAH) that has been found in tobacco smoke and diesel exhaust and has carcinogenic activity.1,2It undergoes metabolic activation by numerous enzymes, including the cytochrome P450 (CYP450) isoform CYP1B1, as well as microsomal epoxide hydrolase (mEH), producing a variety of reactive metabolites that form DNA adductsin vivo, and it has been commonly used to induce tumor formation in various rodent models.2,3,1DMBA increase...
T26960	CB7833407
	CB7833407 is a selective Adenylyl Cyclase isoform-2 (AC2) inhibitor.
T2238L	Cariporide Mesylate Cariporide Mesylate salt,HOE-642,HOE 642,HOE642
	Cariporide Mesylate is a selective inhibitor of the Na+/H+ exchanger isoform 1.
T23566	Zoniporide dihydrochloride	Others	Others
	Sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor
TP2241	[Des-octanoyl]-Ghrelin (human)	Others	Others
	[Des-octanoyl]-Ghrelin (human) is a Non-acylated, major circulating isoform of ghrelin.
T13113	Teglicar	Others	Others
	Teglicar is a selective and reversible liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1) inhibitor.
TP2242	[Des-octanoyl]-Ghrelin (rat)	Others	Others
	[Des-octanoyl]-Ghrelin (rat) is a Non-acylated, major circulating isoform of ghrelin.
T24020	DTS Dibenzyl trisulfide
	DTS is a selective and isoform-specific RSK1 kinase inhibitor. It also has broad cancer therapeutic potential.
T11702	J30-8	Others	Others
	J30-8 exhibits neuroprotective activity in vitro and potential for the treatment of neurodegenerative diseases. J30-8 is a potent and isoform-selective inhibitor of c-Jun N-terminal kinase 3 (JNK3) with an IC50 of 40 nM, which 2500-fold isoform selectivit
T16908	Sonolisib PX-866	PI3K	PI3K/Akt/mTOR signaling
	Sonolisib is an irreversible and pan-isoform inhibitor of PI3K (IC50=0.1 nM (p110α), 1.0 nM (p120γ), 2.9 nM (p110δ)).
T12616	(R)-CE3F4	Others	Others
	(R)-CE3F4 is a selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1)(IC50 of 4.2 μM),
T71513	GK-136901
	GK-136901 is a first-in-class, potent, and orally bioavailable NADPH oxidase isoform 4 (Nox4) inhibitor.
T13359	XPC-6444	Others	Others
	XPC-6444 is a isoform-selective, and CNS-penetrant inhibitor of NaV1.6 with IC50 of41 nM for hNaV1.6,with anticonvulsant activity.
T61874	DN02
	DN02 is a highly potent and selective probe for the BRD8 bromodomain. It demonstrates a marked affinity for the BRD8(1) isoform with a Ki value of 32 nM, exhibiting a 30-fold greater affinity compared to BRD8(2) isoform with a Ki value greater than 1000 nM [1].
T22774	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]	Others	Others
	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed
T14566	BI-9627	Others	Others
	BI-9627 is an inhibitor of sodium-hydrogen exchanger isoform 1 (NHE1) (EC50: 31 nM).
T24224	JTT-010 JTT010
	JTT-010 is a selective inhibitor of protein kinase C-beta isoform.
T40852	(Rac)-γ-Tocopherol (Rac)-γ-Tocopherol,DMPBQ
	(Rac)-γ-Tocopherol (DMPBQ) is an isoform of Vitamin E that undergoes conversion to γ-Tocopherol through the action of tocopherol cyclase.
T37306	6-hydroxy Chlorzoxazone 6-hydroxy Chlorzoxazone,NSC 24955
	6-hydroxy Chlorzoxazone is a metabolite of chlorzoxazone. [1] It is formed by metabolism of chlorzoxazone by the cytochrome P450 (CYP) isoform CYP2E1 in human hepatic microsomes.

化合物

Cat.No: TP2098

Synonym: Echistatin, α1 isoform

Cat.No: T16129

Target: HDAC

Prokineticin 2 Isoform 2 (human)

Cat.No: T76655

Beta-defensin 103 isoform X1, pig

Cat.No: T76064

Beta-defensin 103 isoform X1, pig TFA

Cat.No: T76064L

Cat.No: T12103

Target: PDE

Cat.No: T6704

Synonym: TG100713

Target: PI3K

Cat.No: T2256

Synonym: 1-[4-[[2-(1H-吲唑-4-基)-4-(4-吗啉基)噻吩并[3,2-D]嘧啶-6-基]甲基]-1-哌嗪基]-6-甲基-5-庚烯-1,4-二酮

Target: PI3K

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)

Cat.No: T22774L

Target: Others

Cat.No: T14089

Synonym: AC 261066

Target: Retinoid Receptor

6-Phenyldihydropyrimidine-2,4(1h,3h)-dione

Cat.No: T8584

Synonym: 2,4(1H,3H)-Pyrimidinedione,dihydro-6-phenyl-

Target: Others

Cat.No: T3985

Synonym: GDC 0326,GDC0326

Target: PI3K

Cat.No: T14947

Target: HDAC

(S)-Mephenytoin

Cat.No: T21529

Target: Others

5,6-trans-Vitamin D3

Cat.No: T35501

Synonym: 5,6-trans-Colecalciferol,5,6-trans-Cholecalciferol,Cholecalciferol EP Impurity A

Target: Vitamin

Cat.No: T14090

Target: Retinoid Receptor

Cat.No: T9608

Target: Others

Cat.No: T2057

Target: Dehydrogenase

Cat.No: T1999

Synonym: RG-7604,GDC-0032

Target: PI3K, Carbonic Anhydrase

Cat.No: T2002

Synonym: PF4708671

Target: S6 Kinase, Autophagy

PIK-75 hydrochloride

Cat.No: T2287

Synonym: PIK-75 HCl,2-甲基-5-硝基苯磺酸 [(6-溴咪唑并[1,2-a]吡啶-3-基)亚甲基]甲基肼盐酸盐,PIK-75

Target: Apoptosis, DNA-PK, PI3K

PF-543 hydrochloride

Cat.No: T8840

Synonym: PF-543

Target: Apoptosis, S1P Receptor, Autophagy, LPL Receptor

AGI-41998 tautomers

Cat.No: T64377

Target: Others

Cat.No: T16333

Synonym: Adenylyl cyclase type V Inhibitor

Target: Adenylyl cyclase

Cat.No: T27371

Synonym: FR167356,FR 167356

Target: ATPase

Cat.No: T21938

Target: PI3K

IRE1α kinase-IN-1

Cat.No: T9564

Target: IRE1

Cat.No: T4281

Synonym: (E/Z)-N-desmethyl-4-hydroxy Tamoxifen,N-去甲基-4-羟基-,(E/Z)-Endoxifen

Target: Estrogen Receptor/ERR, Aromatase, Estrogen/progestogen Receptor, Parasite, Drug Metabolite

L-797,591 hydrochloride

Cat.No: T27787L

Synonym: L-797,591 hydrochloride(217480-24-5 Free base)

Cat.No: T24873

Synonym: TGX 115

Target: PI3K

Cat.No: T8944

Target: Calcium Channel

Cat.No: T36696

Cat.No: T26960

Cariporide Mesylate

Cat.No: T2238L

Synonym: Cariporide Mesylate salt,HOE-642,HOE 642,HOE642

Zoniporide dihydrochloride

Cat.No: T23566

Target: Others

[Des-octanoyl]-Ghrelin (human)

Cat.No: TP2241

Target: Others

Cat.No: T13113

Target: Others

[Des-octanoyl]-Ghrelin (rat)

Cat.No: TP2242

Target: Others

Cat.No: T24020

Synonym: Dibenzyl trisulfide

Cat.No: T11702

Target: Others

Cat.No: T16908

Synonym: PX-866

Target: PI3K

Cat.No: T12616

Target: Others

Cat.No: T71513

Cat.No: T13359

Target: Others

Cat.No: T61874

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]

Cat.No: T22774

Target: Others

Cat.No: T14566

Target: Others

Cat.No: T24224

Synonym: JTT010

(Rac)-γ-Tocopherol

Cat.No: T40852

Synonym: (Rac)-γ-Tocopherol,DMPBQ

6-hydroxy Chlorzoxazone

Cat.No: T37306

Synonym: 6-hydroxy Chlorzoxazone,NSC 24955

Cat. No.	Product Name	Target	Signaling Pathways
T2S1797	Santalol 檀香醇；白檀油萜醇;檀香脑,檀香醇	Antioxidant; Antifungal	Microbiology/Virology; oxidation-reduction
	Santalol 是一种檀香醇的 α 和 β-异构体混合物。其中α-santalol 分离自檀香油中，是一种有前途的抗癌药，能够预防口腔癌、前列腺癌、乳腺癌和皮肤癌。
TN1778	Isoformononetin 异刺芒柄花素,黄豆苷元杂质	IL Receptor; Antifection	Immunology/Inflammation; Microbiology/Virology
	Isoformononetin shows fungitoxic activity against Cladosporium sphaerospermum; it also has immunomodulatory activity, it inhibits the differentiation of Th17 cells and B-cell lymphopoesis to promote osteogenesis in estrogen-deficient bone loss conditions.
T5743	Gymnemagenin	Liver X Receptor	Metabolism
	Gymnemagenin 是一种分离自G. sylvestre 的三萜。它具有抗病毒作用，对糖尿病和肥胖症具有潜在的研究价值。
T2949	Alizarin Mordant Red 11,Anthraquinonic,茜素	P450	Metabolism
	Alizarin (Mordant Red 11) 是一种天然红色染料，从茜草植物根部提取得到，已广泛用作纺织品和绘画中的颜料。
T9675	α-Tocotrienol	Endogenous Metabolite	Metabolism
	α-Tocotrienol 是维生素 E 的一种亚型，存在于蔬菜、水果、种子、坚果、谷物和油脂中。α-Tocotrienol 是抗氧化剂，可以降低胆固醇和其他脂类，也是神经保护和抗癌剂，在心血管疾病的保护中发挥作用。
T6491	(-)-(S)-Equol (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol,雌马酚	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	(-)-(S)-Equol (4',7-Dihydroxyisoflavan) 是雌激素受体β的高亲和力配体。
T16837	SAICAR	Others	Others
	SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner (EC50: 0.3 mM).
TN3910	Ecdysone	Apoptosis; ATPase; Glucocorticoid Receptor; Potassium Channel; Sodium Channel; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Endocrinology/Hormones; Membrane transporter/Ion channel; Metabolism
	Ecdysone 是存在于昆虫和草药中的主要类固醇激素，可以激活盐皮质激素受体并诱导细胞凋亡。Ecdysone 的活性代谢物 20-羟基蜕皮激素在协调发育过渡和体内稳态睡眠调节中起重要作用。
T36472	Tetrahydro-11-deoxy Cortisol
	Tetrahydro-11-deoxy cortisol (THS) is the primary urinary metabolite of 11-deoxycortisol. Urinary excretion of THS is elevated in patients with 11β-hydroxylase deficiency, a condition resulting from mutations in the cytochrome P450 (CYP) isoform CYP11B1. Urinary levels of THS are also elevated in patients with adrenocortical carcinoma (ACC) and adrenocortical adenoma (ACA) but are higher in patients with ACC compared to ACA.
T37810	6',7'-Epoxybergamottin
	6'7'-Epoxybergamottin is a furanocoumarin found in grapefruit. It is a potent inhibitor of the cytochrome P450 (CYP) isoform CYP3A4 with an IC50 value of 0.30 ppm in a cell-free assay, 0.33 μM in HL7 human liver cells, and 0.22 μM in S9 human intestine cells. It has been studied in the context of drug interactions with grapefruit constituents. It is found in grapefruit juice at concentrations of 0.1-7.4 μM and inhibits the transport of talinolol , a permeability glycoprotein (P-gp/ABCB1) transpo...

天然产物

Cat.No: T2S1797

Synonym: 檀香醇；白檀油萜醇;檀香脑,檀香醇

Target: Antioxidant, Antifungal

Isoformononetin

Cat.No: TN1778

Synonym: 异刺芒柄花素,黄豆苷元杂质

Target: IL Receptor, Antifection

Cat.No: T5743

Target: Liver X Receptor

Cat.No: T2949

Synonym: Mordant Red 11,Anthraquinonic,茜素

Target: P450

Cat.No: T9675

Target: Endogenous Metabolite

Cat.No: T6491

Synonym: (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol,雌马酚

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

Cat.No: T16837

Target: Others

Cat.No: TN3910

Target: Apoptosis, ATPase, Glucocorticoid Receptor, Potassium Channel, Sodium Channel, Endogenous Metabolite, Autophagy

Tetrahydro-11-deoxy Cortisol

Cat.No: T36472

6',7'-Epoxybergamottin

Cat.No: T37810

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼