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eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]

产品编号 T22774 CAS T22774

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in the brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in the brain, heart, and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes1.

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eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species] Chemical Structure

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species], CAS T22774

规格	价格/CNY	货期
1 mg	￥ 483	待询
5 mg	￥ 1,383	待询
10 mg	￥ 2,283	待询
25 mg	￥ 3,183	待询

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eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species] 的其他形式现货产品:

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)

其他形式的 eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]:

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)
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生物活性

化学信息

存储 & 溶解度

产品描述

体外活性

There are two forms of eEF1A in eukaryotes, eEF1A1 and eEF1A2, both of which possess the same role in protein synthesis2. eEF1A2 was reported to be exclusively expressed in the brain, heart, and skeletal muscle, whereas eEF1A1 is well known to be ubiquitously expressed3. Tetraploid cells produced by impaired chromosomal condensation are eliminated by a novel type of cell death different from caspase-dependent apoptosis. Cell death was associated with the downregulation of eukaryotic translation elongation factor-1 a 1 (eEF1A1/EF-1a) expression in conjunction with the accumulation of its mRNA in processing bodies (P bodies). Importantly, expression of exogenous eEF1A1 was shown to inhibit the caspase-independent cell death, and similar cell death was observed after inducing the expression of short hairpin RNA speci?c for eEF1A12.

分子量	918.04
分子式	C43H67N9O13
CAS No.	T22774

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度

DMSO: ≥91.8mg/mL

计算器

摩尔浓度计算器

稀释计算器

配液计算器

分子量计算器

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剂量换算

对于不同动物的给药剂量换算，您也可以参考 更多...

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10 只，您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL)，如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法：取 50 μL DMSO 主液，加入 300 μL PEG300，混匀澄清，再加 50 μL Tween 80，混匀澄清，再加 600 μL ddH2O, 混匀澄清。

第一步：请输入动物实验的基本信息

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第二步：请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。

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