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Search Results for " apt "
Targets Recommended: Others

111

抑制剂 & 化合物

17

天然产物

20

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T9079 Apostatin-1

Apt-1

Others Others
Apostatin-1 (Apt-1) 是一种新型 TRADD 抑制剂。 Apostatin-1 可以与 TRADD 的 N 末端 TRAF2 结合域上的口袋结合。
T2201 6-Mercaptopurine hydrate

6-Mercaptopurine monohydrate,6-巯基嘌呤(一水合物),6-Mercaptopurine (6-MP) Monohydrate,6-巯基嘌呤 一水合物

Nucleoside Antimetabolite/Analog; Others; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
6-Mercaptopurine hydrate (6-Mercaptopurine monohydrate) 是一种核苷代谢抑制剂。它通过抑制嘌呤代谢来干扰核酸合成,通常与其他药物联合用于白血病的治疗或缓解维持计划。
T22022 Adaptaquin

HIF Angiogenesis; Chromatin/Epigenetic
Adaptaquin 是缺氧诱导因子脯氨酰羟化酶(HIF-PH)的抑制剂。
T28153 Nelivaptan

SSR149415,SR 149415,SR-149415

Vasopressin Receptor GPCR/G Protein
Nelivaptan (SR 149415) 是一种加压素 V1b 受体拮抗剂。
T7624 DAPTA

DAPTA(TFA),D-Ala-peptide T-amide,Adaptavir

HIV Protease; CCR Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
DAPTA (Adaptavir) 是一种合成肽,是 CCR5抑制剂,有抗 HIV 的活性。
T38563 Raptinal

Caspase Apoptosis; Proteases/Proteasome
Raptinal 直接激活 caspase-3 并在多种细胞系中启动内在的 caspase 依赖性细胞凋亡途径。
T10352 APTO-253

LOR-253,LT-253

Apoptosis; c-Myc; KLF Apoptosis; Cell Cycle/Checkpoint; MAPK
APTO-253 (LOR-253) 抑制 c-Myc 表达,稳定 G-四链体 DNA,并诱导急性髓细胞白血病细胞的细胞周期停滞和凋亡。 它通过诱导 KLF4 肿瘤抑制因子介导抗癌活性,具有抗关节炎活性。
T26399 7-Methyl-6-mercaptopurine

7-Methyl-6-thiopurine,6-Mercapto-7-methylpurine

Others Others
7-Methyl-6-mercaptopurine (7-Methyl-6-thiopurine) 是 PRPP 氨基转移酶的抑制剂,抑制 IMP 代谢并阻止嘌呤、DNA 和 RNA 合成。
TP1970L Prosaptide TX14(A) acetate

Prosaptide TX14(A) acetate(196391-82-9 free base)

ERK; GPR Endocrinology/Hormones; GPCR/G Protein; MAPK
Prosaptide TX14(A) acetate 是一种有效的 GPR37L1 和 GPR37 激动剂。 它增加雪旺细胞中的 ERK1 和 ERK2 磷酸化。
T6453 Conivaptan hydrochloride

Vaprisol,盐酸考尼伐坦,Conivaptan HCl,YM 087

Vasopressin Receptor GPCR/G Protein
Conivaptan hydrochloride (Vaprisol) 是一种口服有效的加压素 V2 和 V1A 受体拮抗剂,用于治疗高血容量性低钠血症和正常血容量。
T2326 Tolvaptan

托伐普坦,OPC-41061

Vasopressin Receptor; Autophagy Autophagy; GPCR/G Protein
Tolvaptan (OPC-41061) 是一种可口服的选择性精氨酸加压素受体 2 拮抗剂,可用于治疗低钠血症。
T9046 Morpholinylmercaptobenzothiazole

Others Others
Morpholinylmercaptobenzothiazole 是一种后效快速硫化促进剂。
T19335 Danegaptide Hydrochloride

GAP-134 (Hydrochloride),ZP 1609 Hydrochloride,(4R)-甘氨酰基-4-(苯甲酰基氨基)-L-脯氨酸盐酸盐

Gap Junction Protein Cytoskeletal Signaling
Danegaptide Hydrochloride (GAP-134 (Hydrochloride)) 是一种具有口服活性的间隙连接蛋白选择性修饰剂,具有抗心律不齐的作用。
T0010 6-Mercaptopurine

6-巯基嘌呤,乐疾宁,6-MP,Mercaptopurine,6-巯基嘌呤

Nucleoside Antimetabolite/Analog; Others; Dehydrogenase; Endogenous Metabolite; Autophagy Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
6-Mercaptopurine (6-MP) 是一种具有免疫抑制特性的抗代谢物抗肿瘤剂。它通过抑制嘌呤代谢来干扰核酸合成,通常与其他药物联合用于白血病的治疗或缓解维持计划。
T7098 BAPTA

1,2-双(2-氨基苯氧基)-乙烷-N,N,N`,N`-四乙酸

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
BAPTA 是非渗透性、选择性的钙离子螯合剂,对 Ca2+的亲和力是 Mg2+的 105 倍。它是一个有价值的研究钙在细胞信号传导中的作用的工具。
T83633 1-N-Methyl-4-mercaptohistidine disulfide

Others Others
1-N-Methyl-4-mercaptohistidine disulfide 是一种潜在的杜氏菌叶绿体偶联因子1氧化还原调节剂,是氧化形式的卵硫醇A,抑制光触发的CF1 ATP酶活性。
T26645 Aptiganel

CNS 1102,CNS-1102,CNS1102

NMDAR Neuroscience
Aptiganel (CNS-1102) 是一种非竞争性 NMDA 拮抗剂,是一种多肽,可用于研究急性缺血性卒中。
T7303 LIXIVAPTAN

VPA-985,利伐普坦,WAY-VPA 985

Vasopressin Receptor GPCR/G Protein
Lixivaptan (VPA-985) 是一种具有口服活性的选择性加压素受体 V2 拮抗剂,对人和大鼠的IC50值分别为 1.2 和 2.3 nM。
T1462 Captopril

SQ 14225,甲巯丙脯酸,卡托普利,SQ-14534,SA333

RAAS Endocrinology/Hormones
Captopril (SA333) 是一种含巯基的,具有口服活性的血管紧张素转换酶(ACE)抑制剂 ,IC50=0.025 μM,广泛应用于高血压和充血性心力衰竭的研究。Captopril 也是NDM-1抑制剂,IC50=7.9 μM。
T1414 Sodium 2-mercaptoethanesulfonate

Mitexan,美司那,美司钠,Uromitexan,Mesna,Mesnum,Mesnex

Others Others
Sodium 2-mercaptoethanesulfonate (Uromitexan) 是一种抗氧化剂,具有细胞保护作用。它可用于减轻由环磷酰胺引起的出血性膀胱炎。它广泛用作抗化学疗法毒性的全身保护剂。
T6202 DAPT

LY-374973,GSI-IX

Apoptosis; Beta Amyloid; Gamma-secretase; Autophagy Apoptosis; Autophagy; Neuroscience; Proteases/Proteasome; Stem Cells
DAPT (LY-374973) 是一种 γ 分泌酶抑制剂,抑制总 Aβ 和 Aβ42 (IC50=115/200 nM),具有口服活性。DAPT 也是一种 Notch 抑制剂。DAPT 可以诱导细胞分化、诱导细胞自噬和凋亡。
T8788 Naptalam

Others Others
Naptalam 是一种极性生长素转运抑制剂。它能够对玉米叶片起始、KNOX 蛋白调节和叶缘形成造成破坏。
T34262 RAPTA-C

Apoptosis Apoptosis
RAPTA-C 可通过线粒体和 p53-JNK 途径诱导 EAC 细胞周期停滞和凋亡,可用于研究乳腺癌和卵巢癌。
T16790L Rotigaptide TFA(355151-12-1 free base)

Rotigaptide TFA

Gap Junction Protein Cytoskeletal Signaling
Rotigaptide TFA(355151-12-1 free base) 是一种新型的 Cx43 特异性调节剂,是一种有效的 AAP。 Rotigaptide 可防止 Cx43 介导的间隙连接通讯的解偶联,并使急性代谢应激期间的细胞间通讯正常化。
T14494 Balovaptan

RG7314

Vasopressin Receptor GPCR/G Protein
Balovaptan (RG7314) 是一种高效和选择性的脑渗透性血管加压素 1a (hV1a) 受体拮抗剂,对人类 (hV1a) 和小鼠 (mV1a) 受体的 Ki 值分别为 1 和 39 nM,可用于自闭症的研究。
T6288 Mozavaptan

莫扎伐坦,OPC31260l,OPC-31260

Vasopressin Receptor GPCR/G Protein
Mozavaptan (OPC-31260) 是 benzazepine 衍生物,是一种竞争性加压素受体拮抗剂,作用于 V1 和 V2 受体,IC50 分别为 1.2 μM 和 14 nM。它可在体内拮抗精氨酸加压素的抗利尿作用,可用于低钠血症、抗利尿激素不适当综合征和充血性心力衰竭的研究。
T6245 BAPTA-AM

BAPTA/AM

Potassium Channel Membrane transporter/Ion channel
BAPTA-AM 是一种钙离子螯合剂,具有细胞渗透性和选择性,可以阻断 hERG、hKv1.3 和 hKv1.5 通道 (IC50=1.3/1.45/1.23 μM)。BAPTA-AM对 Ca2+的亲和力是 Mg2+的 105 倍,可以用于钙在细胞信号传导中的作用。
T31249 Deacetylsaptomycin D

Deacetylsaptomycin D is a biochemical.
T34325 Ribuvaptan

Ribuvaptan is a antagonist of vasopressin receptor .
T34680 Sodium stibocaptate

Sodium stibocaptate is a biochemical.
T64256 Emapticap pegol

Emapticap pegol 是一种促炎趋化因子 C-C 基序配体 2 (CCL2) 抑制剂。Emapticap pegol 也是一种 40 个核苷酸的寡核苷酸适体,在人 (NOX-E36) 和小鼠 (mNOX-E36) 中表现出不同的 Spiegelmers (L-RNA 适配子) 形式。
T60530 Mercaptoethylguanidine (MEG) (dihydrobromide)

Mercaptoethylguanidine (MEG) dihydrobromide 是选择性的诱导型一氧化氮合酶抑制剂和过氧亚硝酸盐清除剂,在炎症性肠病研究中具有潜力。
TD0097 BAPTA, tetrapotassium salt

BAPTA-AM,BAPTA 四钾盐

BAPTA, tetrapotassium salt is a Ca2+ chelator.
TP1970 Prosaptide TX14(A)

Potent GPR37L1 and GPR37 agonist (EC50 values are 5 and 7 nM, respectively). Stimulates signaling through pertussis toxin-sensitive G proteins. Stimulates ERK phosphorylation. Protects against cellular stress. Promotes myelin lipid synthesis and prolongs
T35456 (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane

(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane (BMC) is a cyclohexane with two mercaptoacetamido groups. It is used, both in vitro and in vivo, to promote the correct folding of proteins that require disulfide bonds for functionality. For in vitro applications, BMC may be used to facilitate protein refolding of solubilized proteins from inclusion bodies. Reducing agents, like dithiothreitol, may interfere with refolding. BMC may also be added to the growth medium of cells, including yeast cel...
T30108 Aptazapine maleate

CGS7525A,CGS-7525A,CGS 7525A

Aptazapine (CGS 7525A) is a tetracyclic antidepressant (TECA) that is a potent α2-adrenergic receptor antagonist and has also been shown to act as a 5-HT2 receptor antagonist and an H1 receptor reverse agonist, both for serotonin reuptake or norepinephrin
T33881 Paracetamol mercapturate

Paracetamol mercapturate is a deuterated metabolite of acetaminophen.
T25488 Haptamide B

Haptamide-B

Haptamide B is a selective Hap2/3/4/5p mediated transcription inhibitor in vivo.
T30713 Carbamic acid, N-mercapto-N-methyl-, m-isopropylphenyl ester

Carbamic acid, N-mercapto-N-methyl-, m-isopropylphenyl ester is a bioactive chemical.
T60383 Captopril hydrochloride

Captopril (SQ 14225) hydrochloride 是一种含巯基的口服活性血管紧张素转换酶(ACE)抑制剂,IC50值为0.025 μM,已广泛应用于高血压和充血性心力衰竭的研究。Captopril hydrochloride 也是 NDM-1抑制剂,IC50值为 7.9 μM。
T34522 Sarcinapterin

Sarcinapterin is a coenzyme isolated from Methanosarcina barkeri.
T33294 Mercaptomerin sodium

Diucardyn sodium,Mercaptomerine sodique,Thiomerin sodium,Letorin

Mercaptomerin sodium can be used to treat cardiac edema.
T71885 Sodium 2-mercaptobenzothiazole

Sodium 2-mercaptobenzothiazole is the sodium salt of mercaptobenzothiazole, and is used as a copper corrosion inhibitor.
T64663 3-Mercaptopropionic acid NHS ester

3-Mercaptopropionic acid NHS ester 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64663。
T81600 Oregon-BAPTA Green 1AM

Oregon Green 488 BAPTA 1AM

Oregon-BAPTA Green 1AM(Oregon Green 488 BAPTA 1AM)是一种荧光Ca2+指示剂,由绿色荧光探针OG 488和可透过细胞膜的Ca2+螯合剂BAPTA AM组成。
T38068 Aptiganel hydrochloride

Potent and noncompetitive NMDA receptor antagonist (IC50 = 36 nM). Exhibits >70-fold selectivity for NMDA receptor over σ receptor. Neuroprotective in a rat model of focal ischemia.
TP2222 APTSTAT3-9R

Others Others
APTSTAT3-9R-9R is a STAT3 inhibitor (Ki: 231 nmol/L). STAT3 has been reported to promote the proliferation, survival, metastasis, immune escape, as well as drug resistance of cancer cells, making it a promising target for various diseases. However, though
TP2222L APTSTAT3-9R acetate

STAT JAK/STAT signaling; Stem Cells
APTSTAT3-9R acetate 是一种特异性肽结合 STAT3,具有抗增殖和抗肿瘤活性。 APTSTAT3-9R acetate 并通过特异性阻断 STAT3 磷酸化来抑制 STAT3 活化和下游信号传导。
T35971 4-hydroxy Nonenal Mercapturic Acid

Peroxidation of common ω-6 polyunsaturated fatty acids (PUFAs) such as linoleic acid, DGLA, and arachidonic acid can give rise to 4-HNE. 4-HNE is cleared rapidly from the plasma and undergoes enterohepatic circulation as a glutathione conjugate in the rat. About two thirds of an administered dose of 4-HNE is excreted within 48 hours in the urine, primarily in the form of mercapturic acid conjugates. The C-1 aldehyde of 4-HNE is reduced to an alcohol in about half of these metabolites. The remain...
T19830 Dicapthon

AC4124,AC 4124,Captex,ENT-17035,ENT 17035,AC-4124

Dicapthon is an insecticide. Dicapthon increases the occurrence of abnormal cell frequency, decreases the mitotic index, and decreases the nuclear division index.

化合物

Apostatin-1
Cat.No: T9079
Synonym: Apt-1
Target: Others
6-Mercaptopurine hydrate
Cat.No: T2201
Synonym: 6-Mercaptopurine monohydrate,6-巯基嘌呤(一水合物),6-Mercaptopurine (6-MP) Monohydrate,6-巯基嘌呤 一水合物
Target: Nucleoside Antimetabolite/Analog, Others, DNA/RNA Synthesis
Adaptaquin
Cat.No: T22022
Synonym:
Target: HIF
Nelivaptan
Cat.No: T28153
Synonym: SSR149415,SR 149415,SR-149415
Target: Vasopressin Receptor
DAPTA
Cat.No: T7624
Synonym: DAPTA(TFA),D-Ala-peptide T-amide,Adaptavir
Target: HIV Protease, CCR
Raptinal
Cat.No: T38563
Synonym:
Target: Caspase
APTO-253
Cat.No: T10352
Synonym: LOR-253,LT-253
Target: Apoptosis, c-Myc, KLF
7-Methyl-6-mercaptopurine
Cat.No: T26399
Synonym: 7-Methyl-6-thiopurine,6-Mercapto-7-methylpurine
Target: Others
Prosaptide TX14(A) acetate
Cat.No: TP1970L
Synonym: Prosaptide TX14(A) acetate(196391-82-9 free base)
Target: ERK, GPR
Conivaptan hydrochloride
Cat.No: T6453
Synonym: Vaprisol,盐酸考尼伐坦,Conivaptan HCl,YM 087
Target: Vasopressin Receptor
Tolvaptan
Cat.No: T2326
Synonym: 托伐普坦,OPC-41061
Target: Vasopressin Receptor, Autophagy
Morpholinylmercaptobenzothiazole
Cat.No: T9046
Synonym:
Target: Others
Danegaptide Hydrochloride
Cat.No: T19335
Synonym: GAP-134 (Hydrochloride),ZP 1609 Hydrochloride,(4R)-甘氨酰基-4-(苯甲酰基氨基)-L-脯氨酸盐酸盐
Target: Gap Junction Protein
6-Mercaptopurine
Cat.No: T0010
Synonym: 6-巯基嘌呤,乐疾宁,6-MP,Mercaptopurine,6-巯基嘌呤
Target: Nucleoside Antimetabolite/Analog, Others, Dehydrogenase, Endogenous Metabolite, Autophagy
BAPTA
Cat.No: T7098
Synonym: 1,2-双(2-氨基苯氧基)-乙烷-N,N,N`,N`-四乙酸
Target: Reactive Oxygen Species
1-N-Methyl-4-mercaptohistidine disulfide
Cat.No: T83633
Synonym:
Target: Others
Aptiganel
Cat.No: T26645
Synonym: CNS 1102,CNS-1102,CNS1102
Target: NMDAR
LIXIVAPTAN
Cat.No: T7303
Synonym: VPA-985,利伐普坦,WAY-VPA 985
Target: Vasopressin Receptor
Captopril
Cat.No: T1462
Synonym: SQ 14225,甲巯丙脯酸,卡托普利,SQ-14534,SA333
Target: RAAS
Sodium 2-mercaptoethanesulfonate
Cat.No: T1414
Synonym: Mitexan,美司那,美司钠,Uromitexan,Mesna,Mesnum,Mesnex
Target: Others
DAPT
Cat.No: T6202
Synonym: LY-374973,GSI-IX
Target: Apoptosis, Beta Amyloid, Gamma-secretase, Autophagy
Naptalam
Cat.No: T8788
Synonym:
Target: Others
RAPTA-C
Cat.No: T34262
Synonym:
Target: Apoptosis
Rotigaptide TFA(355151-12-1 free base)
Cat.No: T16790L
Synonym: Rotigaptide TFA
Target: Gap Junction Protein
Balovaptan
Cat.No: T14494
Synonym: RG7314
Target: Vasopressin Receptor
Mozavaptan
Cat.No: T6288
Synonym: 莫扎伐坦,OPC31260l,OPC-31260
Target: Vasopressin Receptor
BAPTA-AM
Cat.No: T6245
Synonym: BAPTA/AM
Target: Potassium Channel
Deacetylsaptomycin D
Cat.No: T31249
Synonym:
Target:
Ribuvaptan
Cat.No: T34325
Synonym:
Target:
Sodium stibocaptate
Cat.No: T34680
Synonym:
Target:
Emapticap pegol
Cat.No: T64256
Synonym:
Target:
Mercaptoethylguanidine (MEG) (dihydrobromide)
Cat.No: T60530
Synonym:
Target:
BAPTA, tetrapotassium salt
Cat.No: TD0097
Synonym: BAPTA-AM,BAPTA 四钾盐
Target:
Prosaptide TX14(A)
Cat.No: TP1970
Synonym:
Target:
(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane
Cat.No: T35456
Synonym:
Target:
Aptazapine maleate
Cat.No: T30108
Synonym: CGS7525A,CGS-7525A,CGS 7525A
Target:
Paracetamol mercapturate
Cat.No: T33881
Synonym:
Target:
Haptamide B
Cat.No: T25488
Synonym: Haptamide-B
Target:
Carbamic acid, N-mercapto-N-methyl-, m-isopropylphenyl ester
Cat.No: T30713
Synonym:
Target:
Captopril hydrochloride
Cat.No: T60383
Synonym:
Target:
Sarcinapterin
Cat.No: T34522
Synonym:
Target:
Mercaptomerin sodium
Cat.No: T33294
Synonym: Diucardyn sodium,Mercaptomerine sodique,Thiomerin sodium,Letorin
Target:
Sodium 2-mercaptobenzothiazole
Cat.No: T71885
Synonym:
Target:
3-Mercaptopropionic acid NHS ester
Cat.No: T64663
Synonym:
Target:
Oregon-BAPTA Green 1AM
Cat.No: T81600
Synonym: Oregon Green 488 BAPTA 1AM
Target:
Aptiganel hydrochloride
Cat.No: T38068
Synonym:
Target:
APTSTAT3-9R
Cat.No: TP2222
Synonym:
Target: Others
APTSTAT3-9R acetate
Cat.No: TP2222L
Synonym:
Target: STAT
4-hydroxy Nonenal Mercapturic Acid
Cat.No: T35971
Synonym:
Target:
Dicapthon
Cat.No: T19830
Synonym: AC4124,AC 4124,Captex,ENT-17035,ENT 17035,AC-4124
Target:
Cat. No. Product Name Target Signaling Pathways
T11060 DMAPT

Dimethylamino Parthenolide

NF-κB NF-κB
DMAPT (Dimethylamino Parthenolide) 是一种具有口服活性的NF-κB 抑制剂,是一种 Parthenolide (PTL) 的类似物,对原发性急性髓性白血病细胞的LD50值为1.7 μM。具有潜在的抗肿瘤和抗转移作用。
T19856 2-Mercaptobenzothiazole

Mercaptobenzothiazole,Dermacid,2-巯基苯并噻唑,Captax

Others; Endogenous Metabolite Metabolism; Others
2-Mercaptobenzothiazole (Captax) 是内源性代谢产物的一种。
T1665 Daptomycin

达托霉素,LY146032

DNA/RNA Synthesis; Antibacterial; Antibiotic Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
Daptomycin (LY146032) 是脂肽类抗生素,在体外快速灭活革兰氏阳性细菌。
T2143 Bergapten

5-Methoxypsoralen,佛手柑内酯,香柑内酯

P450; Autophagy Autophagy; Metabolism
Bergapten (5-Methoxypsoralen) 是白芷中的一种香豆素,也是一种补骨脂素,可抑制细胞复制。
TN7233 Pseudobaptigenin

Psi-baptigenin

Others Others
Pseudobaptigenin (Psi-baptigenin) 是一种异黄酮,是一种黄酮类脂质分子,是在Pterocarpus marsupium、Dalbergia spruceana 中发现的一种天然产品。
T5747 ISOBERGAPTEN

Others Others
Isobergapten 是一种化感抑制剂,分离自Hevacleum laciniatum 种子。
TN1345 8-Hydroxybergapten

8-羟基佛手柑内酯,8-羟基佛手苷内酯

Others Others
8-hydroxybergapten 具有优异的抗皱效果。在离散的 O-甲基转移酶介导的反应中,它被 Ruta 细胞的无细胞提取物 O-甲基化为异青霉素。
T4115 Auraptene

橙皮油内酯,7-geranyloxycoumarin,橙皮油素

MMP; BACE Neuroscience; Proteases/Proteasome
Auraptene 是一种丰富的天然香叶氧基香豆素。它能够抑制基质金属蛋白酶 2 以及关键炎症因子,包括 IL-6,IL-8 和趋化因子 (C-C 基序) 配体-5 (CCL5)的分泌。
T2S1434 Bergaptol

5-Hydroxyfuranocoumarin,4-Hydroxybergapten,5-羟基-6,7-呋喃并香豆素,5-Hydroxypsoralen

P450 Metabolism
Bergaptol (4-Hydroxybergapten) 是CYP3A4酶脱苄基作用的抑制剂(IC50:24.92 uM),具有抗癌、抗增殖作用。
T38250 L-Sepiapterin

L-Sepiapterin, also known as Sepiapterin, is a precursor compound crucial for the production of tetrahydrobiopterin (BH4), which serves as a coenzyme for endothelial nitric oxide synthase (eNOS). This compound demonstrates its efficacy by improving endothelial dysfunction in small mesenteric arteries from db/db mice and promoting angiogenesis. Moreover, L-Sepiapterin exerts inhibitory effects on cellular proliferation and migration in ovarian cancer cells through the down-regulation of p70S6K-de...
TN1354 Aaptamine

c-Myc; TNF; p53 Apoptosis; Cell Cycle/Checkpoint
Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.
TMA1241 Apterin

Others Others
Apterin has anti-inflammatory activity in vitro, it shows significantly inhibitory activity on nitric oxide production in RAW264.7 cells.
TN3488 Baptifoline

Others Others
Baptifoline has cytotoxic activity.
TN5875 6′′-O-β-D-Apiofuranosylapterin

6′′-O-β-D-Apiofuranosylapterin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5875,CAS号为 2188162-94-7。
T83239 7-O-Primverosylpseudobaptigenin

7-O-Primverosylpseudobaptigenin为Amur maackia根醇提取物中分离得到的天然产物。
TN6432 Bergaptol O-β-D-glucopyranoside

Bergaptol-beta-glucopyranoside

Bergaptol O-β-D-glucopyranoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6432,CAS号为 131623-13-7。
TN1415 Auraptenol

酸橙素烯醇

5-HT Receptor GPCR/G Protein; Neuroscience
Auraptenol possesses robust antidepressant-like efficacy in mice.

天然产物

DMAPT
Cat.No: T11060
Synonym: Dimethylamino Parthenolide
Target: NF-κB
2-Mercaptobenzothiazole
Cat.No: T19856
Synonym: Mercaptobenzothiazole,Dermacid,2-巯基苯并噻唑,Captax
Target: Others, Endogenous Metabolite
Daptomycin
Cat.No: T1665
Synonym: 达托霉素,LY146032
Target: DNA/RNA Synthesis, Antibacterial, Antibiotic
Bergapten
Cat.No: T2143
Synonym: 5-Methoxypsoralen,佛手柑内酯,香柑内酯
Target: P450, Autophagy
Pseudobaptigenin
Cat.No: TN7233
Synonym: Psi-baptigenin
Target: Others
ISOBERGAPTEN
Cat.No: T5747
Synonym:
Target: Others
8-Hydroxybergapten
Cat.No: TN1345
Synonym: 8-羟基佛手柑内酯,8-羟基佛手苷内酯
Target: Others
Auraptene
Cat.No: T4115
Synonym: 橙皮油内酯,7-geranyloxycoumarin,橙皮油素
Target: MMP, BACE
Bergaptol
Cat.No: T2S1434
Synonym: 5-Hydroxyfuranocoumarin,4-Hydroxybergapten,5-羟基-6,7-呋喃并香豆素,5-Hydroxypsoralen
Target: P450
L-Sepiapterin
Cat.No: T38250
Synonym:
Target:
Aaptamine
Cat.No: TN1354
Synonym:
Target: c-Myc, TNF, p53
Apterin
Cat.No: TMA1241
Synonym:
Target: Others
Baptifoline
Cat.No: TN3488
Synonym:
Target: Others
6′′-O-β-D-Apiofuranosylapterin
Cat.No: TN5875
Synonym:
Target:
7-O-Primverosylpseudobaptigenin
Cat.No: T83239
Synonym:
Target:
Bergaptol O-β-D-glucopyranoside
Cat.No: TN6432
Synonym: Bergaptol-beta-glucopyranoside
Target:
Auraptenol
Cat.No: TN1415
Synonym: 酸橙素烯醇
Target: 5-HT Receptor
Cat. No. Product Name Species Expression System
TMPJ-00702 APT-1 Protein, Human, Recombinant (His)

LPL-I,LPL1,APT-1,Acyl-Protein Thioesterase 1,LYPLA1...

Human E. coli
Acyl-Protein Thioesterase 1 (APT-1) is lysophospholipase that belongs to the AB hydrolase 2 family. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. APT-1 performs on biological membranes to regulate the multifunctional lysophospholipids. It hydrolyzes lysophosphatidylcholine in both monomeric and micellar forms. It hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS; in a...
TMPH-03595 APT Protein, S. pyogenes serotype M1, Recombinant (His & Myc)

Adenine phosphoribosyltransferase,apt,APRT

Streptococcus pyogenes P. pastoris (Yeast)
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. APT Protein, S. pyogenes serotype M1, Recombinant (His & Myc) is expressed in yeast with N-10xHis and C-Myc tag. The predicted molecular weight is 22.7 kDa and the accession number is P63546.
TMPH-00663 APT Protein, E. coli O139:H28, Recombinant (His & Myc)

APRT,apt,Adenine phosphoribosyltransferase

E. coli E. coli
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
TMPY-02132 LYPLA2 Protein, Human, Recombinant (His)

APT-2,lysophospholipase II,DJ886K2.4,APT2

Human E. coli
Lysophospholipase II (LYPLA2, LPL-II, or LysoPLA II), also known as Acyl-protein thioesterase 2 (APT-2), belongs to the AB hydrolase 2 family. This enzyme has lysophospholipase activity and may hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Acyl-protein thioesterase 1 (APT-1) and Acyl-protein thioesterase 2 (APT-2) are cytosolic lysophospholipids hydrolyzing enzymes. The serum activity of APT-1 may play an important role in the dete...
TMPY-00799 Fas/CD95 Protein, Human, Recombinant (hFc)

CD95,FAS1,ALPS1A,APT1,FASTM,TNFRSF6,APO-1,Fas cell ...

Human HEK293 Cells
Fas/CD95 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.4 kDa and the accession number is P25445-1.
TMPY-01704 Fas/CD95 Protein, Human, Recombinant (His)

TNFRSF6,FAS1,ALPS1A,FASTM,Fas cell surface death receptor,

Human HEK293 Cells
Fas/CD95 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.2 kDa and the accession number is P25445-1.
TMPY-01426 Fas/CD95 Protein, Mouse, Recombinant (His)

Fas cell surface death receptor,lpr,CD95,APT1,TNFR6...

Mouse HEK293 Cells
Fas/CD95 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is P25446.
TMPJ-00730 Haptoglobin Protein, Human, Recombinant (C-His)

Zonulin,HP,Haptoglobin

Human HEK293 Cells
Haptoglobin Protein, Human, Recombinant (C-His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 16 and 40-75 KDa and the accession number is P00738.
TMPH-00581 ATP-dependent Clp protease adapter protein ClpS Protein, E. coli, Recombinant (His)

yljA,ATP-dependent Clp protease adapter protein Clp...

E. coli E. coli
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. ATP-dependent Clp protease adapter protein ClpS Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16.2?kDa and the accession number is P0A8Q6.
TMPH-03384 Synaptotagmin-2 Protein, Rat, Recombinant (His)

Rat E. coli
Synaptotagmin-2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 48.7 kDa and the accession number is P29101.
TMPY-04057 Synaptotagmin VI Protein, Human, Recombinant (His)

synaptotagmin VI,sytVI

Human E. coli
Synaptotagmin VI Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 19.4 kDa and the accession number is I6L9C3.
TMPH-03379 Synaptogyrin-1/SYNGR1 Protein, Rat, Recombinant (His)

Rat E. coli
May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation. Involved in the regulation of short-term and long-term synaptic plasticity. Synaptogyrin-1/SYNGR1 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 31.7 kDa and the accession number is Q62876.
TMPH-03380 Synaptophysin/SYP Protein, Rat, Recombinant (His)

Rat E. coli
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin/SYP Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 34.8 kDa and the accession number is P07825.
TMPH-03382 Synaptotagmin-1 Protein, Rat, Recombinant (His)

Rat E. coli
Synaptotagmin-1 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 53.5 kDa and the accession number is P21707.
TMPY-05011 Haptoglobin Protein, Rat, Recombinant (His)

haptoglobin

Rat HEK293 Cells
Haptoglobin Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.1 kDa and the accession number is A6IZ24.
TMPH-02701 Haptoglobin Protein, Mouse, Recombinant (His)

Mouse E. coli
Haptoglobin Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.9 kDa and the accession number is Q61646.
TMPH-02162 Synaptotagmin-1 Protein, Human, Recombinant (His)

Human E. coli
Calcium sensor that participates in triggering neurotransmitter release at the synapse. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at leas...
TMPH-03383 Synaptotagmin-12 Protein, Rat, Recombinant (His)

Rat E. coli
Synaptic vesicle phosphoprotein that enhances spontaneous neurotransmitter release but does not effect induced neurotransmitter release. Unlike other synaptotagmins, it does not bind Ca(2+) or phospholipids. Essential for mossy-fiber long-term potentiation in the hippocampus. Synaptotagmin-12 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 50.7 kDa and the accession number is P97610.
TMPH-03381 Synaptoporin/SYNPR Protein, Rat, Recombinant (His)

Rat E. coli
Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein. Synaptoporin/SYNPR Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 35.2 kDa and the accession number is P22831.
TMPJ-00729 Haptoglobin Protein, Human, Recombinant (N-His)

Haptoglobin,HP,Zonulin

Human E. coli
Haptoglobin Protein, Human, Recombinant (N-His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35 KDa and the accession number is P00738.

重组蛋白

APT-1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00702
Species: Human
Expression System: E. coli
APT Protein, S. pyogenes serotype M1, Recombinant (His & Myc)
Cat.No: TMPH-03595
Species: Streptococcus pyogenes
Expression System: P. pastoris (Yeast)
APT Protein, E. coli O139:H28, Recombinant (His & Myc)
Cat.No: TMPH-00663
Species: E. coli
Expression System: E. coli
LYPLA2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02132
Species: Human
Expression System: E. coli
Fas/CD95 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00799
Species: Human
Expression System: HEK293 Cells
Fas/CD95 Protein, Human, Recombinant (His)
Cat.No: TMPY-01704
Species: Human
Expression System: HEK293 Cells
Fas/CD95 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01426
Species: Mouse
Expression System: HEK293 Cells
Haptoglobin Protein, Human, Recombinant (C-His)
Cat.No: TMPJ-00730
Species: Human
Expression System: HEK293 Cells
ATP-dependent Clp protease adapter protein ClpS Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00581
Species: E. coli
Expression System: E. coli
Synaptotagmin-2 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03384
Species: Rat
Expression System: E. coli
Synaptotagmin VI Protein, Human, Recombinant (His)
Cat.No: TMPY-04057
Species: Human
Expression System: E. coli
Synaptogyrin-1/SYNGR1 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03379
Species: Rat
Expression System: E. coli
Synaptophysin/SYP Protein, Rat, Recombinant (His)
Cat.No: TMPH-03380
Species: Rat
Expression System: E. coli
Synaptotagmin-1 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03382
Species: Rat
Expression System: E. coli
Haptoglobin Protein, Rat, Recombinant (His)
Cat.No: TMPY-05011
Species: Rat
Expression System: HEK293 Cells
Haptoglobin Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02701
Species: Mouse
Expression System: E. coli
Synaptotagmin-1 Protein, Human, Recombinant (His)
Cat.No: TMPH-02162
Species: Human
Expression System: E. coli
Synaptotagmin-12 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03383
Species: Rat
Expression System: E. coli
Synaptoporin/SYNPR Protein, Rat, Recombinant (His)
Cat.No: TMPH-03381
Species: Rat
Expression System: E. coli
Haptoglobin Protein, Human, Recombinant (N-His)
Cat.No: TMPJ-00729
Species: Human
Expression System: E. coli
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