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44

抑制剂 & 化合物

17

天然产物

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Cat. No. Product Name Target Signaling Pathways
T38565 Testosterone glucuronide

Others Others
Testosterone glucuronide 是睾酮的主要尿液代谢物,是一种潜在的尿液生物标记物。
T9170 Testosterone decanoate

Others Others
Testosterone decanoate 是天然存在的雄激素睾酮酯,具有长效男性抗生育活性。
T9035 Testosterone undecanoate

Others; Androgen Receptor Endocrinology/Hormones; Others
Testosterone undecanoate 是一种睾酮酯,是睾酮的代谢产物,睾酮是很有前途的男性激素避孕雄激素。
T38572 Testosterone buciclate

Testosterone buciclate, a long-acting androgen ester, shows promise as a research agent for male hypogonadism.
T34813 Testosterone ketolaurate

Testosterone 3-oxododecanoate,Testosteroni ketolauras,十二酮酸睾酮

Testosterone ketolaurate is an androgen and anabolic steroid and a testosterone ester.
T40653 Testosterone phenylacetate

Testosterone phenylacetate, an analogue of Testosterone, is an androgen.
T28952 Testosterone glucoside

Testosterone glucoside is an androgen receptor agonist.
T13921 Testosterone tridecanoate

Others Others
Testosterone tridecanoate is a prodrug of testosterone. Testosterone is an anabolic steroid and primary male sex hormone.
T34814 Testosterone, amidinohydrazone

V-2052,V2052,V 2052

Testosterone, amidinohydrazone is a biochemical.
T7313 Enclomiphene citrate

恩氯米芬柠檬酸盐,Enclomifene citrate,(E)-Clomiphene citrate,trans-Clomiphene citrate

Estrogen Receptor/ERR Endocrinology/Hormones
Enclomiphene citrate (trans-Clomiphene citrate) 是口服具有活力的 oestrogen receptor 拮抗剂,具有抗雌激素活性。
TP1015 NFAT Inhibitor

VIVIT peptide

Others Others
NFAT Inhibitor (VIVIT peptide) 是NFAT 的细胞渗透性肽抑制剂,能够选择性抑制钙调磷酸酶介导的NFAT 脱磷酸作用。
T34303 Retrotestosterone

Lumitestosterone

Retrotestosterone, a biochemical, can affect testosterone.
T70409 6alpha-Fluorotestosterone

6alpha-Fluorotestosterone is a synthetic nonaromatizable androgen analog of testosterone. It binds to and activates specific nuclear receptors inhibits and is equipotent to testosterone.
T1167 Cyproterone acetate

Androcur,醋酸环丙氯地孕酮,Cyproterone 17-O-acetate,醋酸环丙孕酮

Androgen Receptor Endocrinology/Hormones
Cyproterone acetate (Cyproterone 17-O-acetate) 是能够抗雄激素(IC50=7.1 nM) 和孕激素合成的类固醇。它与 progesteron 和糖皮质激素受体有亲和力。
T3630 Relugolix

RVT-601,瑞卢戈利,TAK-385

GNRH Receptor GPCR/G Protein
Relugolix (RVT-601) 是口服有活性的非肽性促性腺激素释放激素的拮抗剂。同 TAK-013 相比,它对人和猴子的受体具有高亲和力和强拮抗活性,它们的 IC50值分别为0.33 nM 和0.32 nM。它可用于研究性激素依赖性疾病,如子宫肌瘤、子宫内膜异位症、前列腺癌等。
T22025 AG 045572

P450; GNRH Receptor GPCR/G Protein; Metabolism
AG 045572 是一种有效的 GnRH 受体拮抗剂,对人类和大鼠的 GnRH receptor 具有抑制作用, Ki 值分别为 6.0 nM 和 3.8 nM。AG 045572 通过 CYP3A 代谢并抑制睾酮。
T14116 ACP-105

Androgen Receptor Endocrinology/Hormones
ACP-105 是选择性的、可口服的雄激素受体调节剂 , 能够作用于野生型 AR (pEC50:9.0)和 T877A 突变型 AR (pEC50:9.3)。
T13187 Topterone

Win 17665

Androgen Receptor Endocrinology/Hormones
Topterone(Win 17,665) 是一种有效的局部抗雄激素,抑制睾酮和二氢睾酮对阉割未成熟雄性仓鼠腰部器官发育的刺激。
T26539 AC-262536

AC262536,4-(3-内型-羟基-8-氮杂双环[3.2.1]辛烷-8-基)萘-1-甲腈

Androgen Receptor Endocrinology/Hormones
AC-262536 是非甾体雄激素受体选择性调节剂,具有有益的合成代谢作用。它可以强效激动雄激素受体,亲和力为1-10 nM。
T0488 Finasteride

非那雄胺,MK-906

Reductase Endocrinology/Hormones; Metabolism
Finasteride (MK-906) 是 5α-还原酶的竞争性抑制剂,对 II 型 5α-还原酶的IC50为 4.2 nM,对 II 型 5α-还原酶的亲和力是 I 型酶的 100 倍。它可用于研究前列腺增生和雄激素性脱发。
T2556 Nandrolone decanoate

癸酸诺龙,19-Nortestosterone decanoate

Others; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
Nandrolone decanoate (19-Nortestosterone decanoate) 是一种合成代谢雄激素,通过涉及谷氨酸诱导的 N-甲基-D-天冬氨酸受体过度兴奋的机制诱导攻击性行为表征。
T2408 Ostarine

MK-2866,GTX-024,Enobosarm

Androgen Receptor Endocrinology/Hormones
Ostarine (MK-2866) 是一种具有合成代谢活性的非甾体药物。选择性雄激素受体调节剂 (SARM) GTx-024 旨在像睾酮一样发挥作用,从而促进和/或维持性欲、生育能力、前列腺生长以及肌肉生长和力量。模仿睾酮的作用,这种药物可以增加瘦体重,从而改善癌症恶病质高代谢状态下的肌肉萎缩。
T20681 Estramustine

NSC-89201,NSC 89201,LEO 275,LEO275,雌莫司汀,NSC89201,LEO-275

Microtubule Associated Cytoskeletal Signaling
Estramustine (LEO-275) 是一种与雌二醇相连的氮芥,通常为磷酸盐。它已被用于治疗前列腺肿瘤;还具有防辐射功能。它被前列腺细胞选择性吸收,并通过干扰微管动力学和降低血浆睾酮水平发挥抗肿瘤作用。
T0679 Ketoconazole

R-41400,Xolegel,(±)-Ketoconazol,酮康唑,Extina

NADPH-oxidase; P450; Hydroxylase; Antifungal; Ras GPCR/G Protein; Immunology/Inflammation; MAPK; Metabolism; Microbiology/Virology
Ketoconazole (R-41400) 是一种咪唑类抗真菌剂,也是一种 CYP3A4 抑制剂。
T30647 C 881

C-881,C881

C 881 is a raw testosterone propionate material.
T71341 Myclobutanil hydroxide

Myclobutanil hydroxide is a 14-α demethylase inhibitor that inhibits ergosterol synthesis and fungal cell wall formation. It also weakly inhibits testosterone production.
T25390 Estrandron

Estrandron is an agent containing testosterone, estradiol or their derivatives reported in eastern European literature.
T68757 RMI-18341

RMI-18341 is a Testosterone 5 alpha reductase inhibitor.
T70266 Acyline

Acyline is a novel GnRH antagonist found in animal studies to be a potent suppressor of circulating gonadotropin and testosterone (T) levels. Acyline inhibits basal and GnRH-stimulated serum testosterone concentrations in male dogs. Acyline prevented ovulation, but did not affect ovarian follicular development or gestational corpora lutea in the domestic cat. A single dose of the potent gonadotropin-releasing hormone antagonist acyline suppresses gonadotropins and testosterone for 2 weeks in hea...
T24084 Gamendazole

Gamendazole is a novel drug candidate for male contraception. It has been shown to reduce fertility in male rats without affecting testosterone levels.
TP1094 TAK-448

MVT-602

TAK-448 (MVT-602) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM.TAK-448 has been used in trials studying the treatment of Prostate Cancer, Low Testosterone, Prostatic Neoplasms, and Hypogonadotropic Hypogonadism.
T69492 Ozarelix

Ozarelix is a fourth generation GnRH antagonist, induces apoptosis in hormone refractory androgen receptor negative prostate cancer cells modulating expression and activity of death receptors. Mechanistically, LHRH antagonists exert rapid inhibition of luteinizing hormone and follicle stimulating hormone with an accompanying rapid decrease in sex hormones and would therefore be expected to be effective in a variety of hormonally dependent disease states including ovarian cancer, prostate cancer,...
T19194 Androst-4-ene-3,17-diol, dipropanoate, (3β,17β)-

Androst-4-ene-3β,17β-diol, dipropionate

Others Others
Androst-4-ene-3,17-diol, dipropanoate, (3β,17β)- is a metabolite of testosterone.
T75244 Acyline TFA

Acyline TFA,GnRH 多肽类似物,是一种GnRH 拮抗剂,可以抑制促性腺激素和睾酮 (T) 水平。
T68292 GTX-758

GTX-758, also known as Capesaris, is a n orally available, nonsteroidal selective estrogen receptor (ER) alpha agonist with potential antineoplastic activity. Upon administration of GTx-758, this agent suppresses the secretion of the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the pituitary gland through feedback inhibition. In males, the inhibition of LH secretion prevents the synthesis of androgens, including testosterone, by the testes. This may result in ...
T81390 Prolactin-Releasing Peptide (1-31) (rat)

Prolactin-Releasing Peptide (1-31) (rat) 通过减少禁食诱导的大鼠食物摄入,有效提升血浆LH、FSH及睾酮水平。
T79183 SOS1-IN-16

Ras GPCR/G Protein; MAPK
SOS1-IN-16(Comp 54)为SOS1的选择性抑制剂,IC50值为7.2 nM。在以睾酮作为底物的情况下,该化合物对CYP3A4也显示出抑制活性,IC50为8.9 μM,适用于肿瘤学研究。
T62572 Enclomiphene hydrochloride

Enclomiphene ((E)-Clomiphene) hydrochloride 是一种口服具有活力的、有效的非甾体雌激素受体 (estrogen receptor) 拮抗剂,具有抗雌激素作用。Enclomiphene hydrochloride 能够用于研究卵巢功能障碍、睾酮缺乏、男性性腺功能减退症和 type 2 型糖尿病。
T68701 Abarelix acetate

Abarelix acetate is a synthetic third generation gonadotropin-releasing hormone receptor (GnRHR) antagonist. It increases histamine release from rat peritoneal mast cells in vitro and from a human skin model ex vivo. In vivo, abarelix decreases plasma luteinizing hormone (LH) levels six hours post-treatment in castrated rats, with levels returning to baseline within 24 hours.3 Abarelix (2 mg/kg) also transiently decreases plasma testosterone levels in intact rats, with levels returning to baseli...
T74284 SH379

SH379为2-甲基嘧啶-稠合三环二萜衍生物,是具有口服活性的有效抗迟发性性腺机能减退剂。它显著促进StAR与3β-HSD等关键睾酮合成相关酶的表达,并通过调节AMPK/mTOR信号通路刺激自噬。
T76048 TAK-683 acetate

TAK-683 acetate是一种高效的KISS1R激动剂(IC50=170 pM),改善了代谢稳定性。作为九肽metastin的类似物,对人和大鼠的EC50值分别为0.96 nM和1.6 nM。该化合物通过消耗下丘脑GnRH,能够降低血浆FSH、LH、睾酮水平,展示了对研究激素依赖性前列腺癌的潜力。
T35676 17β-hydroxy Exemestane

17β-hydroxy Exemestane is the primary active metabolite of exemestane . It is formed by metabolism of exemestane by the cytochrome P450 (CYP) isoforms CYP1A and CYP4A11. 17β-hydroxy Exemestane is an aromatase inhibitor (IC50 = 69 nM using human placental microsomes) and an androgen receptor (AR) agonist (IC50 = 39.6 nM) that is selective for AR over estrogen receptor α (ERα; IC50 = 21.2 μM). It stimulates growth of AR- and ERα-positive MCF-7 (EC50 = 2.7 μM) and T47D breast cancer cells (EC50s = ...
T76047 TAK-683 TFA

TAK-683 TFA是一种高效的全KISS1R激动剂(IC50=170 pM),拥有较好的代谢稳定性,是九肽metastin的类似物,对KISS1R有激动效应,其对人和大鼠EC50值分别为0.96 nM和1.6 nM。TAK-683 TFA能够降低下丘脑GnRH水平,进而减少血浆FSH、LH、睾酮的浓度,显示出对激素依赖性前列腺癌研究的可能性。
T71142 Tebuconazole-d9

Tebuconazole-d9 is intended for use as an internal standard for the quantification of tebuconazole by GC- or LC-MS. Tebuconazole is a triazole fungicide that is active against both seed and foliar fungi. It inhibits 14α-demethylase isolated from U. maydis and S. bicolor with IC50 values of 0.05 and 0.16 nM, respectively. It inhibits the androgenic effect of the androgen receptor agonist DHT (IC20 = 2.89 µM) and is cytotoxic (EC20 = 38.9 µM) in an MDA-kb2 assay. Tebuconazole (50 and 100 mg/kg per...

化合物

Testosterone glucuronide
Cat.No: T38565
Synonym:
Target: Others
Testosterone decanoate
Cat.No: T9170
Synonym:
Target: Others
Testosterone undecanoate
Cat.No: T9035
Synonym:
Target: Others, Androgen Receptor
Testosterone buciclate
Cat.No: T38572
Synonym:
Target:
Testosterone ketolaurate
Cat.No: T34813
Synonym: Testosterone 3-oxododecanoate,Testosteroni ketolauras,十二酮酸睾酮
Target:
Testosterone phenylacetate
Cat.No: T40653
Synonym:
Target:
Testosterone glucoside
Cat.No: T28952
Synonym:
Target:
Testosterone tridecanoate
Cat.No: T13921
Synonym:
Target: Others
Testosterone, amidinohydrazone
Cat.No: T34814
Synonym: V-2052,V2052,V 2052
Target:
Enclomiphene citrate
Cat.No: T7313
Synonym: 恩氯米芬柠檬酸盐,Enclomifene citrate,(E)-Clomiphene citrate,trans-Clomiphene citrate
Target: Estrogen Receptor/ERR
NFAT Inhibitor
Cat.No: TP1015
Synonym: VIVIT peptide
Target: Others
Retrotestosterone
Cat.No: T34303
Synonym: Lumitestosterone
Target:
6alpha-Fluorotestosterone
Cat.No: T70409
Synonym:
Target:
Cyproterone acetate
Cat.No: T1167
Synonym: Androcur,醋酸环丙氯地孕酮,Cyproterone 17-O-acetate,醋酸环丙孕酮
Target: Androgen Receptor
Relugolix
Cat.No: T3630
Synonym: RVT-601,瑞卢戈利,TAK-385
Target: GNRH Receptor
AG 045572
Cat.No: T22025
Synonym:
Target: P450, GNRH Receptor
ACP-105
Cat.No: T14116
Synonym:
Target: Androgen Receptor
Topterone
Cat.No: T13187
Synonym: Win 17665
Target: Androgen Receptor
AC-262536
Cat.No: T26539
Synonym: AC262536,4-(3-内型-羟基-8-氮杂双环[3.2.1]辛烷-8-基)萘-1-甲腈
Target: Androgen Receptor
Finasteride
Cat.No: T0488
Synonym: 非那雄胺,MK-906
Target: Reductase
Nandrolone decanoate
Cat.No: T2556
Synonym: 癸酸诺龙,19-Nortestosterone decanoate
Target: Others, HIV Protease
Ostarine
Cat.No: T2408
Synonym: MK-2866,GTX-024,Enobosarm
Target: Androgen Receptor
Estramustine
Cat.No: T20681
Synonym: NSC-89201,NSC 89201,LEO 275,LEO275,雌莫司汀,NSC89201,LEO-275
Target: Microtubule Associated
Ketoconazole
Cat.No: T0679
Synonym: R-41400,Xolegel,(±)-Ketoconazol,酮康唑,Extina
Target: NADPH-oxidase, P450, Hydroxylase, Antifungal, Ras
C 881
Cat.No: T30647
Synonym: C-881,C881
Target:
Myclobutanil hydroxide
Cat.No: T71341
Synonym:
Target:
Estrandron
Cat.No: T25390
Synonym:
Target:
RMI-18341
Cat.No: T68757
Synonym:
Target:
Acyline
Cat.No: T70266
Synonym:
Target:
Gamendazole
Cat.No: T24084
Synonym:
Target:
TAK-448
Cat.No: TP1094
Synonym: MVT-602
Target:
Ozarelix
Cat.No: T69492
Synonym:
Target:
Androst-4-ene-3,17-diol, dipropanoate, (3β,17β)-
Cat.No: T19194
Synonym: Androst-4-ene-3β,17β-diol, dipropionate
Target: Others
Acyline TFA
Cat.No: T75244
Synonym:
Target:
GTX-758
Cat.No: T68292
Synonym:
Target:
Prolactin-Releasing Peptide (1-31) (rat)
Cat.No: T81390
Synonym:
Target:
SOS1-IN-16
Cat.No: T79183
Synonym:
Target: Ras
Enclomiphene hydrochloride
Cat.No: T62572
Synonym:
Target:
Abarelix acetate
Cat.No: T68701
Synonym:
Target:
SH379
Cat.No: T74284
Synonym:
Target:
TAK-683 acetate
Cat.No: T76048
Synonym:
Target:
17β-hydroxy Exemestane
Cat.No: T35676
Synonym:
Target:
TAK-683 TFA
Cat.No: T76047
Synonym:
Target:
Tebuconazole-d9
Cat.No: T71142
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T3130 Testosterone phenylpropionate

Testosterone hydrocinnamate,苯丙酸睾酮,Retandrol,Testosterone 17-phenylpropionate

Others Others
Testosterone phenylpropionate (Testosterone 17-phenylpropionate) 是一种长效雄激素。d3-Testosterone phenylpropionate 可用作内标物。
T0419 Testosterone propionate

Others; Androgen Receptor; Transferase Endocrinology/Hormones; Metabolism; Others
Testosterone Propionate is a short acting oil-based injectable formulation of testosterone. Testosterone inhibits gonadotropin secretion from the pituitary gland and ablates estrogen production in the ovaries, thereby decreasing endogenous estrogen levels.
TC0026 Testosterone benzoate

Others Others
Testosterone benzoate 是一种合成的注射合成代谢雄激素类固醇 (AAS) 和一种雄激素酯。
TC0025 Testosterone acetate

NSC523836,NSC-523836,NSC 523836,醋酸睾酮

Others Others
Testosterone acetate (NSC-523836) 是一种 Testosterone 前药,是一种天然存在的雄激素睾酮酯。它可用于阳痿、虚弱、疲劳和性腺机能减退的研究。
T19470 Nandrolone propionate

Others; Androgen Receptor Endocrinology/Hormones; Others
Nandrolone propionate 是合成代谢类固醇,主要由雄激素和保氮剂组成,具有作用时间相对较长的特点。
T8709 Nandrolone phenylpropionate

Nandrolone phenpropionate,苯丙酸诺龙

Androgen Receptor Endocrinology/Hormones
Nandrolone phenylpropionate (Nandrolone phenpropionate) 是一种合成代谢类固醇,是一种 19-nortestosterone 的衍生物。它能够促进蛋白质合成,用于缓解组织分解代谢,可以用于骨质疏松症和特纳综合征的研究。
T5S0543 Isocurcumenol

Apoptosis; Estrogen Receptor/ERR; Reductase Apoptosis; Endocrinology/Hormones; Metabolism
Isocurcumenol 是从莪术中分离得到的一种天然产物,是一种ERα抑制剂,对 DLA 和 KB 癌细胞的IC50分别为 99.1 µg/mL 和 178.2 µg/mL,具有抗肿瘤活性。
T3329 4',7-Dimethoxyisoflavone

4',7-二甲氧基异黄酮,Dimethoxydaidzein,Daidzein dimethyl ether

Endogenous Metabolite; Antifungal Metabolism; Microbiology/Virology
4',7-Dimethoxyisoflavone (Daidzein dimethyl ether) 是从阔荚合欢中分离的黄酮类化合物,有抗真菌作用,可抑制大鼠前列腺睾酮5α-还原酶。
T1009 Estrone

Oestrone,雌酮,Fluoroethyl,Aquacrine

Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Estrone (Aquacrine) 是内源性雌激素的主要代表,由多种组织产生,尤其是脂肪组织。它是脂肪细胞中雄烯二酮芳构化过程的结果。
T4885 (-)-Aspartic acid

(R)-Aspartic acid,Asp,D-(-)-Aspartic acid,D-天门冬氨酸,Aminosuccinic acid,asparagic acid,L-Homoproline,D-Aspartic acid

Endogenous Metabolite; NMDAR; iGluR Membrane transporter/Ion channel; Metabolism; Neuroscience
(-)-Aspartic acid (L-Homoproline) 是一种存在于无脊椎动物和脊椎动物中的内源性氨基酸,是 NMDA 受体激动剂,可调节睾酮合成。
T5264 Androsterone

5alpha-Androsterone,Androkinin,5α-Androstan-3α-ol-17-one,雄甾酮,雄酮

FXR; Endogenous Metabolite; Autophagy Autophagy; Metabolism
Androsterone 是睾酮的代谢产物,可以激活法尼醇 X 受体。
T20976 Clostebol acetate

Clostebolacetate,Clostene,Alfa-Trofodermin,4-CLTA

Clostebol acetate is a synthetic anabolic-androgenic steroid (AAS) and a derivative of testosterone. It acts as a prodrug of clostebol in the body.
TN4604 Myricanone

BCL; HSP; NF-κB; ROS; Caspase; STAT Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; JAK/STAT signaling; Metabolism; NF-κB; Proteases/Proteasome; Stem Cells
Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activation, and suppression of cell proliferation by down-regulation of NF-κB and STAT3 signalling cascades. Myricanone shows in vitro testost
TN2144 Resveratroloside

P450; NO Synthase Immunology/Inflammation; Metabolism
Resveratroloside 是α-glucosidase 的竞争性抑制剂,可以对血糖水平进行调节,对心脏具有保护作用。
TN5682 2,6,4'-Trihydroxy-4-methoxybenzophenone

2,6,4'-Trihydroxy-4-methoxybenzophenone shows weak inhibitory activity of testosterone 5alpha-reductase, it also shows significant inhibition of pancreatic lipase activity. 2,6,4'-Trihydroxy-4-methoxybenzophenone has neurotrophic activity, it induced neurite outgrowth in PC-12 cells at concentration of 50 microg/ml. 2,6,4′-Trihydroxy-4-methoxybenzophenone exhibits low cytotoxic effect against HeLa and 3T3 cell lines with IC50 values of 132 ug/ml and 158 ug/ml, repectively. It also shows antiox...
T37452 Stephacidin B

Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, including testosterone-independent PC3 and -sensitive LNCaP prostate cancer cells (IC50s = 0.37 and 0.06 μM, respectively) and estradiol-independent SK-BR-3 and -sensitive MCF-7 breast cancer cells (IC50s = 0.32 and 0.27 μM, respectively).1It induces apoptosis in HepG2 and Huh7 hepatoc...
TN5153 Torilin

MMP; ERK; IκB/IKK; p38 MAPK; NF-κB; Tyrosinase; Reductase; DNA/RNA Synthesis; JNK Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Endocrinology/Hormones; MAPK; Metabolism; NF-κB; Proteases/Proteasome
Torilin 是一种睾酮5α还原酶抑制剂,它(IC50=31.7+/-4.23μM)对5α还原酶的抑制作用强于α-亚麻酸(IC50=160.3+/-24.62μM),但弱于非那雄胺(IC50=0.38+/-0.06μM)。Torilin 具有免疫调节、肝脏保护和抗炎特性,它通过限制 TAK1介导的 MAP 激酶和 NF-βB 活化来抑制炎症,它可以减轻关节炎的严重程度,改变 dLN 或关节中的白细胞活化,并恢复血清和脾细胞细胞因子失衡。托利林抑制α-黑素细胞刺激激素激活的 B16黑色素瘤细胞中的黑色素生成,IC(50)值为25μM。Torilin 对枯草芽孢杆菌 ATCC 6633孢子和营养细胞表现出优异的抗菌活性。Torilin 在体内和体外都具有强大的抗血管生成活性,它可能通过抑制肿瘤侵袭来抑制肿瘤发生,逆转癌细胞的多药耐药性,它可以增强阿霉素、长春碱、紫杉醇和秋水仙碱对多药耐药 KB-V1和 MCF7/ADR 细胞的细胞毒性。

天然产物

Testosterone phenylpropionate
Cat.No: T3130
Synonym: Testosterone hydrocinnamate,苯丙酸睾酮,Retandrol,Testosterone 17-phenylpropionate
Target: Others
Testosterone propionate
Cat.No: T0419
Synonym:
Target: Others, Androgen Receptor, Transferase
Testosterone benzoate
Cat.No: TC0026
Synonym:
Target: Others
Testosterone acetate
Cat.No: TC0025
Synonym: NSC523836,NSC-523836,NSC 523836,醋酸睾酮
Target: Others
Nandrolone propionate
Cat.No: T19470
Synonym:
Target: Others, Androgen Receptor
Nandrolone phenylpropionate
Cat.No: T8709
Synonym: Nandrolone phenpropionate,苯丙酸诺龙
Target: Androgen Receptor
Isocurcumenol
Cat.No: T5S0543
Synonym:
Target: Apoptosis, Estrogen Receptor/ERR, Reductase
4',7-Dimethoxyisoflavone
Cat.No: T3329
Synonym: 4',7-二甲氧基异黄酮,Dimethoxydaidzein,Daidzein dimethyl ether
Target: Endogenous Metabolite, Antifungal
Estrone
Cat.No: T1009
Synonym: Oestrone,雌酮,Fluoroethyl,Aquacrine
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite
(-)-Aspartic acid
Cat.No: T4885
Synonym: (R)-Aspartic acid,Asp,D-(-)-Aspartic acid,D-天门冬氨酸,Aminosuccinic acid,asparagic acid,L-Homoproline,D-Aspartic acid
Target: Endogenous Metabolite, NMDAR, iGluR
Androsterone
Cat.No: T5264
Synonym: 5alpha-Androsterone,Androkinin,5α-Androstan-3α-ol-17-one,雄甾酮,雄酮
Target: FXR, Endogenous Metabolite, Autophagy
Clostebol acetate
Cat.No: T20976
Synonym: Clostebolacetate,Clostene,Alfa-Trofodermin,4-CLTA
Target:
Myricanone
Cat.No: TN4604
Synonym:
Target: BCL, HSP, NF-κB, ROS, Caspase, STAT
Resveratroloside
Cat.No: TN2144
Synonym:
Target: P450, NO Synthase
2,6,4'-Trihydroxy-4-methoxybenzophenone
Cat.No: TN5682
Synonym:
Target:
Stephacidin B
Cat.No: T37452
Synonym:
Target:
Torilin
Cat.No: TN5153
Synonym:
Target: MMP, ERK, IκB/IKK, p38 MAPK, NF-κB, Tyrosinase, Reductase, DNA/RNA Synthesis, JNK
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